A family of double-stranded DNA viruses containing one genus Asfivirus. It is the source of AFRICAN SWINE FEVER.
Viruses whose nucleic acid is DNA.
A family of DNA plant viruses that infect eukaryotic algae.
Usually refers to planned scientific data-gathering excursions.
A family of nucleocytoplasmic, large, double-stranded DNA viruses with extremely complex genomes.
The salinated water of OCEANS AND SEAS that provides habitat for marine organisms.
A body of water covering approximately one-fifth of the total ocean area of the earth, extending amidst Africa in the west, Australia in the east, Asia in the north, and Antarctica in the south. Including the Red Sea and the Persian Gulf, it constitutes the third largest ocean after the ATLANTIC OCEAN and the PACIFIC OCEAN. (New Encyclopaedia Britannica Micropaedia, 15th ed, 1990, p289)
A subclass of enzymes that aminoacylate AMINO ACID-SPECIFIC TRANSFER RNA with their corresponding AMINO ACIDS.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
A genus of free-living soil amoebae that produces no flagellate stage. Its organisms are pathogens for several infections in humans and have been found in the eye, bone, brain, and respiratory tract.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
The biosynthesis of PEPTIDES and PROTEINS on RIBOSOMES, directed by MESSENGER RNA, via TRANSFER RNA that is charged with standard proteinogenic AMINO ACIDS.
NATIONAL LIBRARY OF MEDICINE service for health professionals and consumers. It links extensive information from the National Institutes of Health and other reviewed sources of information on specific diseases and conditions.
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.
Disruption of structural continuity of the body as a result of the discharge of firearms.
Information intended for potential users of medical and healthcare services. There is an emphasis on self-care and preventive approaches as well as information for community-wide dissemination and use.
Platforms that provide the ability and tools to create and publish information accessed via the INTERNET. Generally these platforms have three characteristics with content user generated, high degree of interaction between creator and viewer, and easily integrated with other sites.
The terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.
Indolesulfonic acid used as a dye in renal function testing for the detection of nitrates and chlorates, and in the testing of milk.
The systematic arrangement of entities in any field into categories classes based on common characteristics such as properties, morphology, subject matter, etc.
International collective of humanitarian organizations led by volunteers and guided by its Congressional Charter and the Fundamental Principles of the International Red Cross Movement, to provide relief to victims of disaster and help people prevent, prepare for, and respond to emergencies.
A plant genus of the family ORCHIDACEAE that is the source of the familiar flavoring used in foods and medicines (FLAVORING AGENTS).
A plant genus of the family Paeoniaceae, order Dilleniales, subclass Dilleniidae, class Magnoliopsida. These perennial herbs are up to 2 m (6') tall. Leaves are alternate and are divided into three lobes, each lobe being further divided into three smaller lobes. The large flowers are symmetrical, bisexual, have 5 sepals, 5 petals (sometimes 10), and many stamens.
The origin of life. It includes studies of the potential basis for life in organic compounds but excludes studies of the development of altered forms of life through mutation and natural selection, which is BIOLOGICAL EVOLUTION.
RNA that has catalytic activity. The catalytic RNA sequence folds to form a complex surface that can function as an enzyme in reactions with itself and other molecules. It may function even in the absence of protein. There are numerous examples of RNA species that are acted upon by catalytic RNA, however the scope of this enzyme class is not limited to a particular type of substrate.
A polynucleotide consisting essentially of chains with a repeating backbone of phosphate and ribose units to which nitrogenous bases are attached. RNA is unique among biological macromolecules in that it can encode genetic information, serve as an abundant structural component of cells, and also possesses catalytic activity. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
An enzyme that catalyses RNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time, and can initiate a chain de novo. (Enzyme Nomenclature, 1992, p293)
Ribonucleic acid that makes up the genetic material of viruses.
The complete genetic complement contained in a DNA or RNA molecule in a virus.
Viruses whose genetic material is RNA.
The relationships of groups of organisms as reflected by their genetic makeup.
The functional hereditary units of VIRUSES.
The type species of ORTHOPOXVIRUS, related to COWPOX VIRUS, but whose true origin is unknown. It has been used as a live vaccine against SMALLPOX. It is also used as a vector for inserting foreign DNA into animals. Rabbitpox virus is a subspecies of VACCINIA VIRUS.
Traumatic injuries to the RECURRENT LARYNGEAL NERVE that may result in vocal cord dysfunction.
Endoscopic surgical procedures performed with visualization via video transmission. When real-time video is combined interactively with prior CT scans or MRI images, this is called image-guided surgery (see SURGERY, COMPUTER-ASSISTED).
Anomaly of the tooth, found chiefly in upper lateral incisors. It is characterized by invagination of the enamel at the incisal edge.

Ultrastructural characterization of the giant volcano-like virus factory of Acanthamoeba polyphaga Mimivirus. (1/41)

Acanthamoeba polyphaga Mimivirus is a giant double-stranded DNA virus defining a new genus, the Mimiviridae, among the Nucleo-Cytoplasmic Large DNA Viruses (NCLDV). We used utrastructural studies to shed light on the different steps of the Mimivirus replication cycle: entry via phagocytosis, release of viral DNA into the cell cytoplasm through fusion of viral and vacuolar membranes, and finally viral morphogenesis in an extraordinary giant cytoplasmic virus factory (VF). Fluorescent staining of the AT-rich Mimivirus DNA showed that it enters the host nucleus prior to the generation of a cytoplasmic independent replication centre that forms the core of the VF. Assembly and filling of viral capsids were observed within the replication centre, before release into the cell cytoplasm where progeny virions accumulated. 3D reconstruction from fluorescent and differential contrast interference images revealed the VF emerging from the cell surface as a volcano-like structure. Its size dramatically grew during the 24 h infectious lytic cycle. Our results showed that Mimivirus replication is an extremely efficient process that results from a rapid takeover of cellular machinery, and takes place in a unique and autonomous giant assembly centre, leading to the release of a large number of complex virions through amoebal lysis.  (+info)

Structural studies of the Sputnik virophage. (2/41)

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Cap analog substrates reveal three clades of cap guanine-N2 methyltransferases with distinct methyl acceptor specificities. (3/41)

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Giant Marseillevirus highlights the role of amoebae as a melting pot in emergence of chimeric microorganisms. (4/41)

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Vaccinia-like cytoplasmic replication of the giant Mimivirus. (5/41)

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mRNA deep sequencing reveals 75 new genes and a complex transcriptional landscape in Mimivirus. (6/41)

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Identification of an L-rhamnose synthetic pathway in two nucleocytoplasmic large DNA viruses. (7/41)

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The three-dimensional structure of Mimivirus. (8/41)

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Define Acanthamoeba polyphaga mimivirus. Acanthamoeba polyphaga mimivirus synonyms, Acanthamoeba polyphaga mimivirus pronunciation, Acanthamoeba polyphaga mimivirus translation, English dictionary definition of Acanthamoeba polyphaga mimivirus. n. pl. mim·i·vi·rus·es Any of a genus of double-stranded DNA viruses that are the largest of all known viruses. n a very large virus containing DNA
Mamavirus is a large and complex virus in the Group I family mimiviridae. The virus is exceptionally large, and larger than many bacteria. Mamavirus and other mimiviridae belong to nucleocytoplasmic large DNA virus (NCLDVs) family. Mamavirus can be compared to the similar complex virus mimivirus; mamavirus was so named because it is similar to but larger than mimivirus. Mamavirus was first reported in September 2008. Like mimivirus, mamavirus was isolated from an amoeba in a cooling tower. The mimiviridae were not discovered until recently because of their size; when filtered the mimiviridae stay with the bacteria which led scientists to believe they were also bacteria. Mimivirus was first isolated in 1992 when scientists were looking for the cause of a pneumonia outbreak in Bradford UK. Due to its size it was named Bradford coccus and put in a freezer with scientists thinking it was a bacterium. A decade later, Jean-Michel Claverie and Didier Raoult discovered Bradford coccus was no ...
During January 2010, a husband and wife returned from Laos to France with probable parasitic disease. Increased antibodies against an Acanthamoeba polyphaga mimivirus virophage indicated seroconversion. While in Laos, they had eaten raw fish, a potential source of the virophage. This virophage, associated with giant viruses suspected to cause pneumonia, could be an emerging pathogen.
The nucleocytoplasmic large DNA viruses, are a new order of viruses that contain the Megavirales or giant viruses. There are nine families of nucleocytoplasmic large DNA viruses (NCLDV) that all share certain genomic and structural characteristics; however, it is uncertain whether the similarities of the different families of this group have a common viral ancestor. One feature of this group is a large genome and the presence of many genes involved in DNA repair, DNA replication, transcription, and translation. Typically, viruses with smaller genomes do not contain genes for these processes. Most of the viruses in this family also replicate in both the nucleus and cytoplasm, thus the name nucleocytoplasmic. There are 47 NCLDV core genes currently recognised. These include four key proteins involved in DNA replication and repair: the enzymes DNA polymerase family B, the topoisomerase II A, the FLAP endonuclease and the processing factor proliferating cell nuclear antigen. Other proteins include ...
Acanthamoeba polyphaga mimivirus (APMV) is the first member of a new family of nucleocytoplasmic large DNA viruses called the Mimiviridae. Another giant virus, named mamavirus, was discovered in 2008 and is considered another APMV strain. Moreover, nosocomially acquired pneumonias account for 10 to 15% of all hospital-acquired infections, and pneumonia is actually the leading cause of nosocomial infection in intensive care units (ICU), where ventilator-associated pneumonias (VAP) are the most frequently observed hospital-acquired infections and are associated with high morbidity and mortality. Mimivirus was one of the agents investigated by serological testing, among other conventional pneumonia agents. Among pneumonia patients with amoeba-associated pathogens, more had seroconversion to mimivirus (5 cases) than to any other pathogen. In addition, mimivirus was second among the four most frequently encountered agents of pneumonia diagnosed with high levels of evidence (3.8%), behind Pseudomonas
Mimivirus. Transmission electron micrograph (TEM) of Acanthamoeba polyphaga mimivirus (APMV) particles. APMV is commonly known as the mimivirus. This virus consists of outer hairs, or fibrils (spikes), and a protein capsid (dark grey) enclosing a core (black) of DNA (deoxyribonucleic acid), the virus genetic material. APMVs classification as a pathogen is tentative, but it is now thought that it may cause viral pneumonia. Magnification: x9,300 when printed 10 centimetres wide. - Stock Image C001/4438
Since the discovery of giant viruses infecting amoebae in 2003, many dogmas of virology have been revised and the search for these viruses has been intensified. Over the last few years, several new groups of these viruses have been discovered in various types of samples and environments.In this work, we describe the isolation of 68 giant viruses of amoeba obtained from environmental samples from Brazil and Antarctica. Isolated viruses were identified by hemacolor staining, PCR assays and electron microscopy (scanning and/or transmission). A total of 64 viruses belonging to the Mimiviridae family were isolated (26 from lineage A, 13 from lineage B, 2 from lineage C and 23 from unidentified lineages) from different types of samples, including marine water from Antarctica, thus being the first mimiviruses isolated in this extreme environment to date. Furthermore, a marseillevirus was isolated from sewage samples along with two pandoraviruses and a cedratvirus (the third to be isolated in the world so far).
Unlabelled: Giant viruses able to replicate in Acanthamoeba castellanii penetrate their host through phagocytosis. After capsid opening, a fusion between the internal membranes of the virion and the phagocytic vacuole triggers the transfer in the cytoplasm of the viral DNA together with the DNA repair enzymes and the transcription machinery present in the particles. In addition, the proteome analysis of purified mimivirus virions revealed the presence of many enzymes meant to resist oxidative stress and conserved in the Mimiviridae. Megavirus chilensis encodes a predicted copper, zinc superoxide dismutase (Cu,Zn-SOD), an enzyme known to detoxify reactive oxygen species released in the course of host defense reactions. While it was thought that the metal ions are required for the formation of the active-site lid and dimer stabilization, megavirus chilensis SOD forms a very stable metal-free dimer. We used electron paramagnetic resonance (EPR) analysis and activity measurements to show that the
So when Didier Raoult and his colleagues in France one day observed that a virophage known as Zamilon was no longer able to successfully infect the giant virus it was previously known to attack (a mimivirus), they wondered if a CRISPR-like immune system was to blame. Sure enough, they found that Zamilon-resistant giant viruses contained snippets of the virophages DNA in their own genomes. Furthermore, when they studied the sequence of the DNA surrounding the Zamilon snippets in the mimivirus, they found that this DNA encoded a gene product that unwinds DNA, and another one that cleaves it. To test whether these two genes were responsible for the giant viruss ability to ward off Zamilon infection, the researchers silenced each flanking gene. The result? The mimiviruses were suddenly vulnerable to Zamilon. Raoult and his colleagues named the newly-identified immunity segment of viral DNA MIMIVIRE, which stands for mimivirus virophage-resistance element. They suggest MIMIVIRE acts as a viral ...
Acanthamoeba polyphaga mimivirus (APM), a virus of free-living amebae, has reportedly caused human respiratory disease. Using 2 newly developed real-time PCR assays, we screened 496 respiratory specimens from 9 pneumonia-patient populations for APM. This virus was not detected in any specimen, which suggests it is not a common respiratory pathogen ...
Acanthamoeba polyphaga mimivirus (APM), a virus of free-living amebae, has reportedly caused human respiratory disease. Using 2 newly developed real-time PCR assays, we screened 496 respiratory specimens from 9 pneumonia-patient populations for APM. This virus was not detected in any specimen, which suggests it is not a common respiratory pathogen.
The discovery of giant viruses with genome and physical size comparable to cellular organisms, remnants of protein translation machinery and virus-specific parasites (virophages) have raised intriguing questions about their origin. Evidence advocates for their inclusion into global phylogenomic studies and their consideration as a distinct and ancient form of life. Here we reconstruct phylogenies describing the evolution of proteomes and protein domain structures of cellular organisms and double-stranded DNA viruses with medium-to-very-large proteomes (giant viruses). Trees of proteomes define viruses as a fourth supergroup along with superkingdoms Archaea, Bacteria, and Eukarya. Trees of domains indicate they have evolved via massive and primordial reductive evolutionary processes. The distribution of domain structures suggests giant viruses harbor a significant number of protein domains including those with no cellular representation. The genomic and structural diversity embedded in the viral
Mimivirus, Acanthamoeba polyphaga, cryo-electron microscope, Atomic Force Microscope, fiber, DIGESTION, starfish-shaped feature, 5-fold symmetry, nucleocapsid, major capsid ...
Lineage: Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes; Imitervirales; Mimiviridae; unclassified Mimiviridae; Klosneuvirinae; ...
Researchers have found that mimiviruses, a class of giant viruses, have an immune system reminiscent of the CRISPR system used by bacteria to evade infection.. As CRISPR has been adapted by scientists as a powerful genome-editing tool, the finding raises the possibility that this newly discovered system - dubbed MIMIVIRE - could be harnessed in a similar way.. Mimiviruses were first discovered by the same team of researchers 13 years ago. They are around four times the size of other viruses like HIV or influenza and can contain hundreds more genes.. A few years ago, the researchers, led by Professor Didier Raoult of Aix-Marseille University in France, found that a type of virophage (a virus that infects other viruses) could infect mimiviruses and stop them replicating. However, some types of mimivirus were resistant to virophage infection.. Professor Raoult and his team suspected this resistance might have its origins in an immune system similar to that found in bacteria. CRISPR sequences are a ...
In freshwater lakes, microbes regulate the flow of carbon and determine if the bodies of water serve as carbon sinks or carbon sources. Algae and cyanobacteria in particular can trap and use carbon, but their capacity to do so may be impacted by viruses. Viruses exist amidst all bacteria, usually in a 10-fold excess, and are made up of various sizes ranging from giant viruses, to much smaller viruses known as virophages (which live in giant viruses and use their machinery to replicate and spread.)
Viruses have a ubiquitous presence in the world. Their population is estimated to be 1031, 10 times greater than the nonillion (1030) of microbes on the planet -- a figure that surpasses the number of stars in the Milky Way. Giant viruses are characterized by disproportionately large genomes and virions that house the viruses genetic material. They can encode several genes potentially involved in protein biosynthesis, a unique feature which has led to diverging hypotheses about the origins of these viruses. But after discovering a novel group of giant viruses with a more complete set of translation machinery genes than any other virus known to date, scientists at the U.S. Department of Energy Joint Genome Institute (DOE JGI), a DOE Office of Science User Facility, believe that this group (dubbed Klosneuviruses) significantly increases our understanding of viral evolution ...
Hidden in the permafrost https://www.france-bioinformatique.fr/en/training_material/hidden-permafrost https://tess.elixir-europe.org/materials/hidden-in-the-permafrost-c83267ed-68a6-4f10-b584-9f9eaae52009 The last decade witnessed the discovery of four families of giant viruses infecting Acanthamoeba. They have genome encoding from 500 to 2000 genes, a large fraction of which encoding proteins of unknown origin. These unique proteins meant to recognize and manipulate the same building blocks as cells raise the question on their origin as well as the role viruses played in the cellular word evolution. The Mimiviridae and the Pandoraviridae are increasingly populated by members from very diverse habitats and are ubiquitous on the planet. After prospecting the space, we went back in the past and isolated two other giant virus families from a 30,000 years old permafrost sample, Pithovirus and Mollivirus sibericum. A metagenomics study of the sample was performed to inventory its biodiversity and ...
Background The discovery of giant viruses with genome and physical size comparable to cellular organisms, remnants of protein translation machinery and virus-specific parasites (virophages) have raised intriguing questions about their origin. harbor a significant number of protein domains including those with no cellular representation. The genomic and structural diversity embedded in the viral proteomes is comparable to the cellular proteomes of organisms with parasitic lifestyles. Since viral domains are widespread among cellular species, we propose that viruses mediate gene transfer between cells and crucially enhance biodiversity. Conclusions Results call for a change in the way viruses are perceived. They likely represent a distinct form of life that either predated or coexisted with the last universal common ancestor (LUCA) and constitute a very crucial part of our planets biosphere. Background The last few years have seen a dramatic increase 1217448-46-8 supplier in our knowledge of ...
Acanthamoeba species are infected by the largest known DNA viruses. These include icosahedral Mimiviruses, amphora-shaped Pandoraviruses, and Pithovirus sibericum, the latter one isolated from 30,000-y-old permafrost. Mollivirus sibericum, a fourth type of giant virus, was isolated from the same permafrost sample. Its approximately spherical virion (0.6-µm diameter) encloses a 651-kb GC-rich genome encoding 523 proteins of which 64% are ORFans; 16% have their closest homolog in Pandoraviruses and 10% in Acanthamoeba castellanii probably through horizontal gene transfer. The Mollivirus nucleocytoplasmic replication cycle was analyzed using a combination of
Of all the Megavirales members, faustovirus shared the largest number of orthologs, as defined by the bidirectional best-hit strategy (45), with ASFV. Thus, the faustovirus and ASFV protein sequences comprised 52 pairs of orthologs that shared 21 to 50% identity; 13 of these 52 genes were not found in any other members of the Megavirales. In addition, phylogenies of several conserved genes of Megavirales, including that encoding the family B DNA polymerase, showed that faustovirus E12 and other faustovirus isolates were distantly related to ASFV (Fig. 3; see Fig. S5 at http://www.mediterranee-infection.com/article.php?laref=373&titer=faustovirus). Nevertheless, this evolutionary relationship was supported only by analysis of a relatively small number of shared genes, constituting only ≈12% of the faustovirus gene complement. In addition, several features were found to differ significantly between faustovirus and ASFV. They included an ≈3 times larger genome in faustovirus and a G+C content ...
A giant virus under a microscope looks like this. To keep abreast of the latest scientific discoveries, subscribe to our news channel in Telegram. In general, researchers believe that the newthe virus comes from an unknown isolated group of viruses or distant relatives of a giant virus, which acquired a reduced form during evolution. Giant viruses were discovered in the twenty-first century. These organisms reach the size of a bacterial cell. Because of capsid - the protein coat that encapsulates viral particles, the virus is called giant. The DNA of a giant virus exceeds 200,000 base pairs and contains Orfan genes that are not found in other organisms.. Read more interesting articles on our channel in Yandex.Zen Yaravirus is composed of small particles with a size of 80 nmand has a unique genome. According to the researchers, it is simple and does not contain giant particles, but at the same time, a significant amount of previously undescribed genes is observed in Yaravirus. Scientists intend ...
A new study of giant viruses supports the idea that viruses are ancient living organisms and not inanimate molecular remnants run amok. Learn more on EarthSky.
Study of giant viruses reveals that all viruses might have evolved from bacteria by shedding functions and DNA, but maintaing similar intelligence.
Two newly discovered giant viruses are bigger than many bacteria and carry massive and largely unique genomes that hint at new branches of life.
J.-P. Baudoin, S. Hari, D. Sahmi-Bounsiar, S. Traoré, J. Bou-Khalil, et al.. Correlative light electron microscopy of giant viruses with the SECOM system. New Microbes and New Infections, Wiley Online Library 2018, 26, pp.110-113. ⟨10.1016/j.nmni.2018.09.006⟩. ⟨hal-02006237⟩ ...
Although the mimivirus virion proteome has already been reported (28, 29), we were interested to reexamine the composition of mature virions by applying mass spectrometry procedures identical to those used for examination of the factories. A total of 236 mimivirus proteins were detected in mature viral particles (see Tables S1 and S2 in the supplemental material) in contrast to the 114 reported in reference 29, a discrepancy likely due to the higher sensitivity of the instrumentation used in this study. Comparison of the protein content of mature virions to the protein content of 4-h VFs (Fig. 4B) revealed that 139 proteins are shared, including six helicases and seven transcription factors (see Tables S1 and S2), supporting the notion that massive replication and transcription processes occur already at this stage (26). In comparisons of the protein content of 7-h viral factories to that of mature virions, 213 proteins were found to be common (Fig. 4C). There were 13 proteins in the virion that ...
Since the discovery of the giant mimivirus, evolutionarily related viruses have been isolated or identified from various environments. Phylogenetic analyses of this group of viruses, tentatively referred to as the family
Last week we discussed the second known virophage, but we didnt have any explanation of why such viruses might evolve. This week we have the discovery of a third virophage, hints of many more, and a hypothesis for what they might be doing in the global ecosystem. The newest virus eater is called Organic Lake
The unusual size and genetic content of enormous viruses could explain the origin of DNA-based life -- one could set up shop in a cell and simply never leave, gradually taking over the remaining functions once performed by its hosts genetic material. But a new study argues this scenario is backwards, as giant viruses may have once been cells.
A battle is brewing between two research groups over whether a CRISPR-like, DNA based defense system in mimivirus that confers resistance to virophage.
This episode: Giant virus in newly discovered microscopic marine predator encodes several light-harvesting proteins! Download Episode (7.8 MB, 11.4 minutes) Show notes: Microbe of the episode: Dolphin mastadenovirus A News item Takeaways Giant viruses are distinct in many ways from other viruses, even aside from their size. One way is the large number and variety of genes they carry in their genome. Though many of their genes are unknown in origin and function, many others appear to take the place of essential reproductive functions, such as translation and protein synthesis. This allows them to assume more control of their hosts metabolism and control its resources more optimally. In this study, the sequence of a giant virus was discovered seemingly infecting a newly discovered microscopic marine predator. The eukaryotic cell feeds on smaller microbes such as bacteria, but strangely, the virus carries genes for several light-harvesting proteins, possibly converting a heter…
PubMed journal article: Distant Mimivirus relative with a larger genome highlights the fundamental features of Megaviridae. Download Prime PubMed App to iPhone, iPad, or Android
From July 19 to 23, scientists lined up samples of some of the largest known viruses on the planet for an extensive X-ray photo shoot that may produce the highest-resolution 3-D images yet of these mysterious specimens - and bring researchers closer to understanding their functions and origins.
In the general excitement of a time when three-dimensional protein structures of whole genomes are being determined automatically, it is often forgotten that a structure in itself does not tell one how the molecule works or folds. For that, one needs to know a great deal about mechanism, intermediates, structural dynamics and molecular interactions. We gather this information using a wide range of biochemical and biophysical techniques, including molecular biology, transient kinetics and crystallography, mass spectrometry, and computation, to understand how the jigglings and wigglings of atoms underlie and contribute to biological function. We study light-induced reactions and those that make use of flavin or heme cofactors, the unique biochemical pathways in anamoxosomes, giant viruses and their virophages as well as their assembly. In addition, we are using X-ray free-electron lasers for structural biology, exploring and further developing their applications. ...
Its like Six Degrees of Kevin Bacon, except with virophages! And in my case, it seems to be closer to two or three degrees. Its happened again. Provirophages and transpovirons as the diverse mobilome of giant viruses Edited by James L. Van Etten, University of Nebraska-Lincoln, Lincoln, NE Dr. Van Etten is one of my…. ...
Genome of largest viruses yet discovered hints at fourth domain of life. | Bioinformatics, Comparative Genomics and Molecular Evolution
Since the isolation of the first giant virus, the Mimivirus, by T.J. Rowbotham in a cooling tower in Bradford, UK, and after its… Expand ...
tags: virology, mimivirus, sputnik, virophage, microbiology, molecular biology Now heres an astonishing discovery thats hot off the presses: a virus that infects other viruses! This amazing finding is being published tomorrow in the top-tier peer-reviewed journal, Nature.. ...
RAR-srodni orfan receptori (ROR) su članovi familije nuklearnih receptora intracelularnih transkripcionih faktora.[1][2] Postoje tre forme ROR, ROR-α, -β, i -γ i svaki je kodiran posebnim genom (RORA, RORB, i RORC respektivno). ROR proteini us donekle neuobičajeni u tome da se oni izgleda da se vezuju kao monomeri za elemente hormonskog odgovora što je u kontrastu sa većinom drugih nuklearnih receptora koji se vezuju kao dimeri.[3]. ...
This Week in Virology and Futures in Biotech join together in a science mashup to talk about a virophage at the origin of DNA transposons, and unintended spread
Plant vs Animal Hormones The form and function of multi cellular organisms requires efficient communication between cells, tissues, organs etc. In these
Résumé: Chrysochromulina ericina virus CeV-01B (CeV) was isolated from Norwegian coastal waters in 1998. Its icosahedral particle is 160 nm in diameter and encloses a 474-kb double-stranded DNA (dsDNA) genome. This virus, although infecting a microalga (the haptophyceae Haptolina ericina, formerly Chrysochromulina ericina), is phylogenetically related to members of the Mimiviridae family, initially established with the acanthamoeba-infecting mimivirus and megavirus as prototypes. This family was later split into two genera (Mimivirus and Cafeteriavirus) following the characterization of a virus infecting the heterotrophic stramenopile Cafeteria roenbergensis (CroV). CeV, as well as two of its close relatives, which infect the unicellular photosynthetic eukaryotes Phaeocystis globosa (Phaeocystis globosa virus [PgV]) and Aureococcus anophagefferens (Aureococcus anophagefferens virus [AaV]), are currently unclassified by the International Committee on Viral Taxonomy (ICTV). The detailed ...
TY - JOUR. T1 - Interactions of some common pathogenic bacteria with Acanthamoeba polyphaga. AU - Huws, Sharon A.. AU - Morley, Robert J.. AU - Jones, Martin V.. AU - Brown, Michael R. W.. AU - Smith, Anthony W.. N1 - ID number: ISI:000255137900016. PY - 2008. Y1 - 2008. N2 - Protozoan grazing is a major trophic pathway whereby the biomass re-enters the food web. Nonetheless, not all bacteria are digested by protozoa and the number known to evade digestion, resulting in their environmental augmentation, is increasing. We investigated the interactions of Bacillus cereus, Enterococcus faecalis, Enteropathogenic Escherichia coli (EPEC), Listeria monocytogenes, Salmonella enterica serovar Typhimurium, and methicillin-sensitive Staphylococcus aureus (MSSA), with the amoeba, Acanthamoeba polyphaga. There was evidence of predation of all bacterial species except L. monocytogenes and S. aureus, where extracellular numbers were significantly higher when cultured with amoebae compared with growth in the ...
Using metagenome data sets collected over several years in northern freshwater lakes, a team led by researchers at The Ohio State University and the U.S. Department of Energy Joint Genome Institute (DOE JGI), a DOE Office of Science User Facility, uncovered 25 novel sequences of virophages. Reported October 11, 2017 in Nature Communications, the identification of these novel sequences effectively doubles the number of virophages known since their discovery a decade ago.. Usually metagenome data sets are one-offs, said DOE JGI scientist and first author Simon Roux. People had started to see virophages in metagenomes, but no one had a long time-series until now. Was it here once? Always? We never really knew this, but its a critical piece of information to understand their importance.. The work stemmed from a Community Science Program (CSP) proposal involving northern freshwater lakes by KT (Trina) McMahon of the University of Wisconsin-Madison. Samples of microbial communities in Lake ...
View Notes - Unit 01 Flashcards from PSIO 201 at Arizona. Class I Double-stranded DNA T4; pox viruses; lambda phage; mimivirus (APMV); Sputnik (virophage) Class II Single-stranded DNA Chicken anemia
mRNA deep sequencing reveals 75 new genes and a complex transcriptional landscape in Mimivirus Matthieu Legendre, Stéphane Audic, Olivier Poirot, Pascal Hingamp, Virginie Seltzer, Deborah Byrne, Audrey Lartigue, Magali Lescot, Alain Bernadac, Julie Poulain, Chantal Abergel and Jean-Michel Claverie Published in Advance April 1, 2010, doi:10.1101/gr.102582.109Mimivirus, a virus infecting Acanthamoeba, is the prototype of the…
Virology Highlights features highlighted articles published in Virology, with posts summarizing the research in the authors words.
Regarding mechanisms. In the Leger et al. paper we cite many papers that discuss potential mechanisms in detail (inter-kingdom conjugation, viral transduction, gene transfer from endosymbionts). If one still finds it hard to believe that genes can get moved around between eukaryote genomes, then consider the rate of discovery of new eukaryotic viruses lately -- it is likely that we have only found the tip of the iceberg. Consider for example, a recently described giant virus in the green alga Tetraselmis (Schvarcz CR and Steward GF (2018) A giant virus infecting green algae encodes key fermentation genes. Virology 518:423-433). Two of the host-derived genes encoded in this virus are in fact involved in anaerobic pyruvate metabolism (pyruvate formate lyase and its activating enzyme). These are the same genes as found in anaerobic protists functioning in their mitochondria (see Stairs et al (2011) Mol. Biol. Evol. 28:2087-99 or Müller et al. (2012)). Couple this observation with the findings of ...
A dormant mega-virus in an ice core drilled in Siberia infected an amoeba, proving in theory that dangerous viruses could be revived.
Unlike most viruses circulating today, these ancient specimens dating from the last Ice Age are not only bigger, but far more complex genetically.
RAR-srodni orfan receptor beta (ROR-beta), ili NR1F2 (nuklearni receptor potfamilije 1, grupe F, član 2), je nuklearni receptor kodiran genom RORB. Protein kodiran ovim genom je član NR1 potfamilije nuklearnih hormonskih receptora. To je DNA-vezujući protein koji se može vezati kao monomer ili homodimer za elemente hormonskog odgovora uzvodno od nekoliko gena da bi pojačao ekspresiju tih gena. Specifične funkcije ovog proteina su nepoznate, ali se zna da ima interakciju sa NM23-2, nukleozid difosfat kinazom koja učestvuje u organogenezi i diferencijaciji.[1] ...
Entries in the haiku/limerick contest, and explain how a giant virus infects a host within another host (it has to do with predators!).
According to Reference.com, cellular organisms that do not have a distinct nucleus, such as bacteria, are called prokaryotes. They are distinct from the eukaryotes, which are the cellular organisms...
Virus nu geus katalungtik, lolobana boga ukuran kapsid 10 jeung 300 nanométer (diaméter). Pikeun babandingan, virion ukuran sedeng dibandingkeun jeung kutu téh sarua jeung ukuran manusa dibandingkeun jeung gunung nu badagna dua kalieun Gunung Everest. Sababaraha filovirus panjangna bisa nepi ka 1400 nm, tapi diaméter kapsidna mah kira ukur 80 nm. Najan lolobana mah moal katempo ku mikroskop cahya, aya ogé virus nu leuwih badag batan baktéri nu pangleutikna antukna bisa katempo mun maké pembesaran nu cukup. Pikeun nempo partikel virus, nu ilahar dipaké nyaéta mikroskop éléktron, boh transmisi atawa skén. Virus nu anyaran kapanggih, mimivirus, teu galib ti nu séjén, diaméterna 400 nm. Virus pangbadagna ieu ukuran génomna nepi ka 1000 gén (sababaraha baktéri ngan boga 400) nu panjangna 1,2 mégabasa. Génomna ieu ngandung loba gén nu homolog jeung gén prokaryote sarta eukaryote[2]. Papanggihan ieu ngajurung para élmuwan mikiran deui kontrovérsi sabudeureun organisme jeung ...
Herpesviruses constitute a family of large DNA viruses widely spread in vertebrates and causing a variety of different diseases. low sequence similarity, suggesting that function may be more conserved than sequence. By combining interactomes of 1818-71-9 different species we were able to systematically address the low coverage of the Y2H system and to extract biologically […]. ...
Lineage: cellular organisms; Bacteria; unclassified Bacteria; Bacteria candidate phyla; Candidatus Saccharibacteria; unclassified ...
Click on a taxon to see the following taxons, if there are any.. By placing the mouse over a node a tooltip will appear. This tootip contains the taxonomic path from Cellular organisms to the node and, in the case of a species, the number of peroxidases in the orthogroup, the total number of peroxidases for that species in the orthogroups class and where possible the names of those peroxidases. The common ancestor for the orthogroup is written in bold in the tooltip. Return to orthogroup ...
Click on a taxon to see the following taxons, if there are any.. By placing the mouse over a node a tooltip will appear. This tootip contains the taxonomic path from Cellular organisms to the node and, in the case of a species, the number of peroxidases in the orthogroup, the total number of peroxidases for that species in the orthogroups class and where possible the names of those peroxidases. The common ancestor for the orthogroup is written in bold in the tooltip. Return to orthogroup ...
Trypanonsome - a group of flagella|flagellated single cellular organisms (protozoa) which cause disease in vertebrate hosts The causative agents of many...
... part of extended Mimiviridae, a clade distinct from Mimiviridae proper; (Imitervirales) Dinodnavirus - possibly under ... For this reason it has been proposed adding them to legacy Mimiviridae as new subfamily Mesomimivirinae in order to form the ... 2013). "Mimiviridae: clusters of orthologous genes, reconstruction of gene repertoire evolution and proposed expansion of the ... For this reason, the term Mimiviridae was used sensu lato synonymous with Megaviridae. However, since the ICTV has created a ...
Phylogenetic tree topology of Mimiviridae is still under discussion. Some authors (CNS 2018) like to put Klosneuviruses ... Nucleocytoplasmic large DNA viruses Girus Mimiviridae Schulz, Frederik; Yutin, Natalya; Ivanova, Natalia N.; Ortega, Davi R.; ...
The genus is currently unassigned but hypothesized to be a member of the family Mimiviridae, along with the other amoeba- ... Unlike the other mimiviruses in the Mimiviridae, tupanvirus has a ~550 nm long cylindrical tail covered with fibrils that is ... Members of the family Mimiviridae includes the type species Acanthamoeba polyphaga mimivirus (APMV) that is known for its large ... phylogenomic results revealed that the genus Tupanvirus is separate from the other viruses in the family Mimiviridae. The ...
Phylogenetic tree topology of Mimiviridae is still under discussion. As Klosneuviruses are related to Mimivirus, it was ... Nucleocytoplasmic large DNA viruses Giant Virus Viral eukaryogenesis Mimiviridae Schulz, Frederik; Yutin, Natalya; Ivanova, ... a proposed subfamily of the Mimiviridae. Species in this clade include Bodo saltans virus infecting the kinetoplastid Bodo ...
ALV presumably parasitizes species of the Mimiviridae virus family. John Stewart: Antarctica - An Encyclopedia. Bd. 1, ...
Maruyama, Fumito; Ueki, Shoko (2016). "Evolution and Phylogeny of Large DNA Viruses, Mimiviridae and Phycodnaviridae Including ... Pandoraviridae and Mimiviridae) are named nucleocytoplasmic large DNA viruses. Because of their large genome sizes and various ...
All three Sputnik virophages share more than 99% of their DNA and can grow with viruses of any Mimiviridae group A, B, and C. ... Zamilon virophage was the first one found infecting a member of Mimiviridae group C (i. e. Mont1 virus), being able to grow ... Gaia M, Pagnier I, Campocasso A, Fournous G, Raoult D, et al: Broad spectrum of mimiviridae virophage allows its isolation ... Sputnik virophages were found infecting giant viruses of Mimiviridae group A. However, they are able to grow in amoebae ...
... is a genus of giant viruses, in the family Mimiviridae. Amoeba serve as their natural hosts. This genus contains a ... Viralzone: Mimiviridae International Committee on Taxonomy of Viruses (ICTV) picture gallery-images of mimivirus. Van Etten, ... has been placed into a viral family by the International Committee on Taxonomy of Viruses as a member of the Mimiviridae, and ...
The mimiviridae were not discovered until recently because of their size; when filtered the mimiviridae stay with the bacteria ... The mimiviridae contain very similar genomes due to gene duplications, and a fair piece of the genome is associated with ... Mamavirus and other mimiviridae belong to nucleocytoplasmic large DNA virus (NCLDVs) family. Mamavirus can be compared to the ... While the mimiviridae were a surprise themselves, mamavirus contained an even bigger surprise. While looking at mamavirus under ...
Pagnier, Isabelle; Reteno, Dorine-Gaelle Ikanga; Saadi, Hanene (2013). "A Decade of Improvements in Mimiviridae and ...
Zamilon is restricted in its range of helper viruses; it can be supported by viruses from Mimivirus-like Mimiviridae lineages B ... Of the 20 predicted products, 15 are similar to those of Sputnik, and three are similar to Mimiviridae: two to Megavirus ... Zamilon was first isolated in association with Mont1, a Mimivirus-like Mimiviridae classified in lineage C by its polymerase B ... All known virophages are associated with helpers in the giant DNA virus family Mimiviridae. ...
Figure 3) Maruyama, Fumito & Ueki, Shoko (30 November 2016). "Evolution and phylogeny of large DNA viruses, Mimiviridae and ... but in fact may rather be a member of an extended family Mimiviridae (aka Megaviridae) than of the family Phycodnaviridae. "' ...
Mimiviridae. Hidden categories: *Wikipedia introduction cleanup from February 2018. *All pages needing cleanup ...
It preys on Organic Lake phycodnaviruses, which in fact may rather belong to Mimiviridae than to Phycodnaviridae. The genome is ... and Organic Lake phycodnavirus a part of the Phycodnaviridae or Mimiviridae?, on ResearchGate, Jan. 8, 2016 "Organic Lake ...
m Mimiviridae‎; 00:12 . . (-239)‎ . . ‎. Tom.Reding. (talk , contribs)‎ (Add from=Q1378923 to {{Taxonbar}}; WP:GenFixes on, ...
CroV is the sole member of the genus Cafeteriavirus in the family Mimiviridae within the proposed order Megavirales. ...
The Bodo saltans virus is a giant virus of the Mimiviridae family that infects the protozoa Bodo saltans. It has a genome of ...
All giant viruses have dsDNA genomes and they are classified into several families: Mimiviridae, Pithoviridae, Pandoraviridae, ...
The species is known for being infected by a giant virus, the Bodo saltans virus, a member of the Mimiviridae family. Mitchell ...
In 2015,CeV was fully sequenced to classify it as a mimiviridae It was more recently proposed a group of mimiviridae infecting ... Chrysochromulina ericina virus 01B, or simply Chrysochromulina ericina virus (CeV) is a giant virus in the family Mimiviridae ... last enzyme is typically used for repairing DNA damage caused by UV light which is consistent with the habitat of a mimiviridae ... Microalga-Infecting Large DNA Viruses Highlights Their Intricate Evolutionary Relationship with the Established Mimiviridae ...
... both belonging to the Mimiviridae (aka Megaviridae) family, due to their having the largest capsid diameters of all known ... both species within the Mimiviridae family, as well as the discovery of seven aminoacyl tRNA synthetase genes, including the ... four genes present in Mimiviridae, in the megavirus genome provide evidence for a possible scenario in which these large DNA ...
... and Mimiviridae (1200 kb). Hytrosaviruses encode homologs to the core and highly conserved oral infectivity factor (PIF) genes ...
... is present in both Eukarya and Mimiviridae but not in Lokiarchaeota that are considered the nearest archaeal relatives of ...
Marseilleviridae Matonaviridae Mayoviridae Medioniviridae Megabirnaviridae Mesoniviridae Metaviridae Microviridae Mimiviridae ...
Mimiviridae Langkodede vira med tykke skaller, måske en overgang mellem bakterier og vira ...
The majority of Mimiviridae appear to belong to this subfamily (Mimiviruses). It is sometimes also referred to as Mimiviridae ... Mimiviridae is a family of viruses. Amoeba and other protists serve as natural hosts. The family is divided in up to 4 ... Viruses in Mimiviridae have icosahedral and round geometries, with between T=972 and T=1141, or T=1200 symmetry. The diameter ... Broad spectrum of mimiviridae virophage allows its isolation using a mimivirus reporter. Mimiviruses have been associated with ...
When retroviruses have integrated their own genome into the germ line, their genome is passed on to a following generation. These endogenous retroviruses (ERVs), contrasted with exogenous ones, now make up 5-8% of the human genome.[7] Most insertions have no known function and are often referred to as "junk DNA". However, many endogenous retroviruses play important roles in host biology, such as control of gene transcription, cell fusion during placental development in the course of the germination of an embryo, and resistance to exogenous retroviral infection. Endogenous retroviruses have also received special attention in the research of immunology-related pathologies, such as autoimmune diseases like multiple sclerosis, although endogenous retroviruses have not yet been proven to play any causal role in this class of disease.[8] While transcription was classically thought to occur only from DNA to RNA, reverse transcriptase transcribes RNA into DNA. The term "retro" in retrovirus refers to ...
The hepatitis envelope proteins are composed of subunits made from the viral preS1, preS2, and S genes. The L (for "large") envelope protein contains all three subunits. The M (for "medium") protein contains only preS2 and S. The S (for "small") protein contains only S. The genome portions encoding these envelope protein subuntis share both the same frame and the same stop codon (generating nested transcripts on a single open reading frame. The pre-S1 is encoded first (closest to the 5' end), followed directly by the pre-S2 and the S. When a transcript is made from the beginning of the pre-S1 region, all three genes are included in the transcript and the L protein is produced. When the transcript starts after the pro-S1 at the beginning of the pre-S2 the final protein contains the pre-S2 and S subunits only and therefore is an M protein. The smallest envelope protein containing just the S subunit is made most because it is encoded closest to the 3' end and comes from the shortest transcript. ...
Viruses in Betanodavirus are non-enveloped, with icosahedral geometries, and T=3 symmetry. The diameter is around 30 nm. Genomes are linear and segmented, bipartite, around 21.4kb in length.[8]. The crystal structure of a betanodavirus- T=3 Grouper nervous necrosis virus (GNNV)-like particle has been determined by X-ray crystallography. The virus-like particle contains 180 subunits of the capsid protein, and each capsid protein (CP) shows three major domains: (i) the N-terminal arm, an inter-subunit extension at the inner surface; (ii) the shell domain (S-domain), a jelly-roll structure; and (iii) the protrusion domain (P-domain) formed by three-fold trimeric protrusions. [10]. ...
Nucleic acid analysis suggests a very long association of the viruses with the wasps (greater than 70 million years).. Two proposals have been advanced for how the wasp/virus association developed. The first suggests that the virus is derived from wasp genes. Many parasitoids that do not use PDVs inject proteins that provide many of the same functions, that is, a suppression of the immune response to the parasite egg. In this model, the braconid and ichneumonid wasps packaged genes for these functions into the viruses-essentially creating a gene-transfer system that results in the caterpillar producing the immune-suppressing factors. In this scenario, the PDV structural proteins (capsids) were probably "borrowed" from existing viruses.. The alternative proposal suggests that ancestral wasps developed a beneficial association with an existing virus that eventually led to the integration of the virus into the wasp's genome. Following integration, the genes responsible for virus replication and the ...
The majority of Mimiviridae appear to belong to this subfamily (Mimiviruses). It is sometimes also referred to as Mimiviridae ... Mimiviridae is a family of viruses. Amoeba and other protists serve as natural hosts. The family is divided in up to 4 ... Viruses in Mimiviridae have icosahedral and round geometries, with between T=972 and T=1141, or T=1200 symmetry. The diameter ... Broad spectrum of mimiviridae virophage allows its isolation using a mimivirus reporter. Mimiviruses have been associated with ...
Mimiviridae References[edit]. * La Scola, B., Audic S., Robert, C., Jungang, L., de Lamballerie, X., Drancourt, M., Birtles, R ... Index of Viruses - Mimiviridae (2009). In: ICTVdB - The Universal Virus Database, version 4. Büchen-Osmond, C. (Ed), Columbia ... Familia: Mimiviridae Genera: Cafeteriavirus - Mimivirus Name[edit]. ... Retrieved from "https://species.wikimedia.org/w/index.php?title=Mimiviridae&oldid=3282400" ...
Tagged as: induced pluripotent stem cell, innate immunity, iPSC, lentille virus, mimiviridae, mimivirus, mobilome, nuclear ... mimiviridae, mimivirus, NCLDV, plaque assay, rhodopsin photosystem, single-cell genomics, viral, viral evolution, virology, ...
As Mimiviridae members are found to infect an increasing range of phytoplanckton species, their taxonomic position compared to ... During the 15 following years, the isolation of many Mimivirus-relatives, have made the Mimiviridae one of the largest and most ... Mimiviridae: A Rising Family of Highly Diverse Large Aquatic dsDNA Viruses Infecting a Wide Variety of Eukaryotes. Jean-Michel ... mimiviridae; algal virus; giant virus; phycodnaviridae; aquatic virus Copyright: This is an open access article distributed ...
Mimiviridae; Mimivirus). The fact that the majority of the 35 Megaviridae reads corresponded to D5 family primases may be ... Mimiviridae.) and the node for oomycetes (NCBI taxonomy: Eukaryota; stramenopiles; oomycetes.) attracted our attention, as ...
Mimiviridae. Hidden categories: *Wikipedia introduction cleanup from February 2018. *All pages needing cleanup ...
m Mimiviridae‎; 00:12 . . (-239)‎ . . ‎. Tom.Reding. (talk , contribs)‎ (Add from=Q1378923 to {{Taxonbar}}; WP:GenFixes on, ...
3.53% of the reads obtained were analogous to those of viruses denoting Siphoviridae, Myoviridae, Podoviridae, Mimiviridae, ...
Mimiviridae. Genus. Mimivirus. Family. Nimaviridae. Genus. Whispovirus. Family. Papillomaviridae. Genus. Alphapapillomavirus. ...
Mimiviridae: An Expanding Family of Highly Diverse Large dsDNA Viruses Infecting a Wide Phylogenetic Range of Aquatic ...
... part of extended Mimiviridae, a clade distinct from Mimiviridae proper; (Imitervirales) Dinodnavirus - possibly under ... For this reason it has been proposed adding them to legacy Mimiviridae as new subfamily Mesomimivirinae in order to form the ... 2013). "Mimiviridae: clusters of orthologous genes, reconstruction of gene repertoire evolution and proposed expansion of the ... For this reason, the term Mimiviridae was used sensu lato synonymous with Megaviridae. However, since the ICTV has created a ...
First Isolation of a Giant Virus from Wild Hirudo medicinalis Leech: Mimiviridae isolation in Hirudo medicinalis ...
First Isolation of a Giant Virus from Wild Hirudo medicinalis Leech: Mimiviridae isolation in Hirudo medicinalis ...
3 (Herpesviridae, Mimiviridae, unclassified virus). 9,181. 9,339. BH 81/11 DNA. 89,728. 79,742. 9. 44. 1 (Retroviridae). 3. ...
The family Mimiviridae, comprised by giant DNA viruses, has been increasingly studied since the isolation of the Acanthamoeba ... The family Mimiviridae, comprised by giant DNA viruses, has been increasingly studied since the isolation of the Acanthamoeba ... Keywords: Mimiviridae, pan-genome, genomics, giant virus, mimivirus. Citation: Assis FL, Franco-Luiz APM, dos Santos RN, Campos ... The family Mimiviridae, comprised by giant DNA viruses, has been increasingly studied since the isolation of the Acanthamoeba ...
Megavirales Composing a Fourth Domain of Life: Mimiviridae and Marseilleviridae Philippe Colson, Didier Raoult ...
Viruses › dsDNA viruses, no RNA stage › Mimiviridae › unclassified Mimiviridae. Proteomes (1) UniProtKB (996)- Unreviewed ( ... Viruses › dsDNA viruses, no RNA stage › Mimiviridae › unclassified Mimiviridae. Proteomes (1) UniProtKB (807)- Unreviewed ( ... Viruses › dsDNA viruses, no RNA stage › Mimiviridae › Mimivirus. Proteomes (5) UniProtKB (6,598)- Reviewed (Swiss-Prot) (909) ...
Lineage: Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes; Imitervirales; Mimiviridae; unclassified ...
Mimiviridae. VMC of Mimiviridae mimivirus (Q5UPV8). 2.A.29.27.1. The ATP exchanger/symporter, LcnP (secreted via the bacterial ...
Mimiviridae. ATPase of Tupanvirus soda lake. *3.A.3.8.23. Possible lipid flipping P-type ATPase of 809 aas and 7 putative TMSs ...
The Mimiviridae family is still expanding (6) and diversifying with more distant and smaller representatives (both in terms of ... the Mimiviridae. They share a unique external fiber layer enclosing a pseudoicosahedral protein capsid of about 0.5 μm in ... Acanthamoeba polyphaga moumouvirus represents a third lineage of the Mimiviridae that is close to the Megavirus lineage. Genome ... In contrast with Mimiviridae, Pandoraviruses replication cycle involves (and disrupts) the host nucleus. ...
Virophages seem to be highly abundant in the environment and occupy the same niches as the Mimiviridae and their hosts. ... Virophages seem to be highly abundant in the environment and occupy the same niches as the Mimiviridae and their hosts. ... 2009). Mimivirus and Mimiviridae: giant viruses with an increasing number of potential hosts, including corals and sponges. J. ... Virophages seem to be highly abundant in the environment and occupy the same niches as the Mimiviridae and their hosts. ...
Exploration of the propagation of transpovirons within Mimiviridae reveals a unique example of commensalism in the viral world ...
Tupanvirus, a new genus in the family Mimiviridae. Archives of Virology 164: 325-331. DOI: 10.1007/s00705-018-4067-4 Reference ...
Giant viruses infecting phagocytic protists are composed of mimiviruses, the record holders of particle and genome size amongst viruses, and marseilleviruses. Since the discovery in 2003 at our laboratory of the first of these giant viruses, the Mimivirus, a growing body of data has revealed that th …
Acanthamoeba polyphaga moumouvirus represents a third lineage of the Mimiviridae that is close to the megavirus lineage. Genome ...
Mimiviridae Langkodede vira med tykke skaller, måske en overgang mellem bakterier og vira ...
Zamilon, a novel virophage with Mimiviridae host specificity. PLoS One9:e94923. doi:10.1371/journal.pone.0094923. ... thus expanding the Mimiviridae family, especially the Mimivirus genus (3-7). These viruses have some genetic differences which ... Acanthamoeba polyphaga moumouvirus represents a third lineage of the Mimiviridae that is close to the Megavirus lineage. Genome ...
... is the first member of a new family of nucleocytoplasmic large DNA viruses called the Mimiviridae. Another giant virus, named ... Data for and against Mimiviridae pathogenicity. Citation: Colson P, Raoult D. 2010. Is Acanthamoeba polyphaga Mimivirus an ... Mimivirus and Mimiviridae: giant viruses with an increasing number of potential hosts, including corals and sponges. J. ... is the first member of a new family of nucleocytoplasmic large DNA viruses called the Mimiviridae. Another giant virus, named ...
  • Phycodnaviridae and Pandoraviridae of Algavirales are sister groups of Mimiviridae in many phylogenetic analyses. (wikipedia.org)
  • CeV 01) Aureococcus anophagefferens virus (AaV) Pyramimonas orientalis virus (PoV) Tetraselmis virus (TetV-1) This group seems to be closely related to Mimiviridae rather than to Phycodnaviridae and therefore is sometimes referred to as a further subfamily candidate Mesomimivirinae. (wikipedia.org)
  • As Mimiviridae members are found to infect an increasing range of phytoplanckton species, their taxonomic position compared to the traditional Phycodnaviridae (i.e. etymologically "algal viruses") became a source of confusion in the literature. (preprints.org)
  • by phylogeny Imitervirales Mimiviridae Algavirales Phycodnaviridae (Pandoraviridae? (wikipedia.org)
  • Viruses of the families Phycodnaviridae and Mimiviridae were present at significant levels in high-diversity soil samples and were found to co-occur, implying little competition between them. (biomedcentral.com)
  • We obtained 313 putative algal virus operational taxonomic units (vOTUs), all classified by phylogenetic analyses to either the Phycodnaviridae or Mimiviridae families, most of them in clades without any cultured or environmental reference sequences. (uib.no)
  • Among the 27 other cancers, viral sequences were detected in only 5 specimens by blast analysis, compared to in all 27 specimens by HMM (Mimiviridae, Poxviridae, Phycodnaviridae and virus-related sequences yet unclassified to any family). (cdc.gov)
  • Phycodnaviridae and Mimiviridae viruses were the second-most-abundant taxa and more numerous within open soil. (waikato.ac.nz)
  • Utilising a novel OTU based assessment, we also show a prevalence of dsDNA viruses belonging to the Mimiviridae, Caudovirales and Phycodnaviridae in reef environments and further highlight the abundance of ssDNA viruses belonging to the Circoviridae, Parvoviridae, Bidnaviridae and Microviridae in reef invertebrates. (bvsalud.org)
  • Sputnik virophages target the Mimiviridae , Mavirus was identified with the Cafeteria roenbergensis virus, and virophage genomes reconstructed by metagenomic analyses may be associated with the Phycodnaviridae . (wordpress.com)
  • Most sequences with matches to eukaryotic viruses were assigned to six viral families, including four Nucleocytoplasmic Large DNA Viruses (NCLDVs) families: Iridoviridae, Phycodnaviridae, Mimiviridae, and Poxviridae, as well as Retroviridae and Polydnaviridae. (univie.ac.at)
  • Mimiviridae is a family of viruses. (wikipedia.org)
  • With recognition of new order Imitervirales by the ICTV im march 2020 there is no longer need to extend the Mimiviridae family to comprise a group of viruses of the observed high diversity. (wikipedia.org)
  • Viruses in Mimiviridae have icosahedral and round geometries, with between T=972 and T=1141, or T=1200 symmetry. (wikipedia.org)
  • Index of Viruses - Mimiviridae (2009). (wikimedia.org)
  • Abergel, C. Mimiviridae: An Expanding Family of Highly Diverse Large dsDNA Viruses Infecting a Wide Phylogenetic Range of Aquatic Eukaryotes. (preprints.org)
  • During the 15 following years, the isolation of many Mimivirus-relatives, have made the Mimiviridae one of the largest and most diverse family of eukaryotic viruses isolated from aquatic environments. (preprints.org)
  • Traditionally only these viruses have been grouped into a family Mimiviridae. (wikipedia.org)
  • The family Mimiviridae , comprised by giant DNA viruses, has been increasingly studied since the isolation of the Acanthamoeba polyphaga mimivirus (APMV), in 2003. (frontiersin.org)
  • Author Affiliations Abstract Mimivirus, a virus infecting Acanthamoeba, is the prototype of the Mimiviridae, the latest addition to the nucleocytoplasmic large DNA viruses. (pearltrees.com)
  • Abstract Acanthamoeba polyphaga Mimivirus is a giant double-stranded DNA virus defining a new genus, the Mimiviridae, among the Nucleo-Cytoplasmic Large DNA Viruses (NCLDV). (pearltrees.com)
  • A multitude of viruses is readily detectable in specimens with cancers occurring among the immunosuppressed, with sequences related to Mimiviridae being the most prevalent. (cdc.gov)
  • We came back in April 2010, expecting to isolate additional members of the Mimiviridae, still believed to be the sole family of giant viruses. (nature.com)
  • Mimivirus is part of the Mimiviridae, a group of "giant viruses", which compared with viruses most people are for familiar, with such as influenza virus, HIV, or Ebola virus, are unusual in many ways. (blogspot.com)
  • Following a previous #MicroTwJC discussion on the largest discovered viruses, this fairly recent paper describes a satellite virus (or virophage) named Zamilon that is associated with the giant virus family Mimiviridae . (wordpress.com)
  • Despite the fact that the Sputnik virophages were isolated with viruses belonging to group A of the Mimiviridae , they can grow in amoebae infected by Mimiviridae from groups A, B or C. In this study we describe Zamilon, the first virophage isolated with a member of group C of the Mimiviridae family. (wordpress.com)
  • Group: dsDNA Order: Imitervirales Family: Mimiviridae *Cafeteria roenbergensis virus *Acanthamoeba polyphaga mimivirus Family Mimiviridae is currently divided into three subfamilies. (wikipedia.org)
  • Broad spectrum of mimiviridae virophage allows its isolation using a mimivirus reporter. (wikipedia.org)
  • The HMM analysis identified 86 additional previously not described viral contigs related to 11 virus families, with reads related to Mimiviridae being the most common (detected in 28/62 NMSCs) with the most prevalent contig (Mimivirus SE906, 1937 bp) detected in 17/62 NMSCs. (cdc.gov)
  • In addition, the proteome analysis of purified mimivirus virions revealed the presence of many enzymes meant to resist oxidative stress and conserved in the Mimiviridae. (archives-ouvertes.fr)
  • Some of the most well-studied ones include the mimivirus (Mimiviridae) and the marseillevirus (Marseilleviridae). (sciencewithevie.com)
  • Virophages seem to be highly abundant in the environment and occupy the same niches as the Mimiviridae and their hosts. (frontiersin.org)
  • Zamilon, a Novel Virophage with Mimiviridae Host Specificity. (mpg.de)
  • Furthermore, it has been proposed either to extend Mimiviridae by an additional tentative group III (subfamily Mesomimivirinae) or to classify this group as a sister family Mesomimiviridae instead, comprising legacy OLPG (Organic Lake Phycodna Group). (wikipedia.org)
  • Following a rapid history of the key discoveries that established the Mimiviridae family, we describe its current taxonomic structure and propose a set of operational criteria to help in the classification of future isolates. (preprints.org)
  • Tupanvirus , a new genus in the family Mimiviridae. (wikimedia.org)
  • Earlier this year, the discovery of two new strains in the Mimiviridae family in Brazil were found to have incredibly complex coding genes. (sciencealert.com)
  • Overall, the analyses revealed that Namao virus is a member of the Mimiviridae family with strong and consistent support for a clade containing NV and CroV as sister taxa. (usgs.gov)
  • Among the 62 NMSCs, the virus family detected in the largest proportion of specimens was Mimiviridae (9/62 NMSCs). (cdc.gov)
  • This virus founded the family Mimiviridae . (biomedcentral.com)
  • Lucky as all beginners, we brought back the first marine Mimiviridae from this trip, now known as Megavirus chilensis , establishing the world-wide distribution of the family, and a new world record for viral genome size ( 1,259,197 base pairs) (PNAS 2011) . (nature.com)
  • Cafeteria roenbergensis virus represents a second group, though the Mimiviridae family is still expanding. (ird.fr)
  • It is sometimes also referred to as Mimiviridae group I. The second subfamily (Cafeteriavirus or Mimiviridae group II) includes the Cafeteria roenbergensis virus (CroV). (wikipedia.org)
  • En biologisk virus består af et genom af DNA eller RNA og et antal enzymer, der er indlejret i en proteinkappe (kaldet en kapsid ), eventuelt omkrandset af membrankappe . (wikipedia.org)
  • Virus kan ikke formere sig alene, men overtager i stedet for en værtscelle og underkaster værtscellens molekylære maskineri for at fremstille kopier af sig selv og således producere den næste generation. (wikipedia.org)
  • Derfor bliver virus typisk ikke betragtet som levende organismer, fordi de alene ikke kan formere sig eller lave stofskifte , men kræver en vært . (wikipedia.org)
  • Dog har nye genetiske undersøgelser ændret på denne opfattelse, da det har vist sig at virus nedstammer fra en fælles stamform med moderne celler og har været en faktor, der har præget evolutionen . (wikipedia.org)
  • Virus består af et genom og nogle gange et par enzymer , der er indlejret i en proteinkappe (kaldet en kapsid ), eventuelt omkranset af membrankappe (en lipid-membran, eng. (wikipedia.org)
  • Virus kan ikke formere sig alene, men overtager i stedet for en værtscelle, dvs. (wikipedia.org)
  • Mimiviridae is the sole recognized member of order Imitervirales. (wikipedia.org)
  • Genus Tequatrovirus ( T4virus , T4-ähnliche Viren , en. (wikipedia.org)
  • The majority of Mimiviridae appear to belong to this subfamily (Mimiviruses). (wikipedia.org)
  • One group is composed of three lineages, referred to as A, B and C, which include the vast majority of the Mimiviridae members. (ird.fr)
  • alternatively the extended group may be referred to just as Mimiviridae. (wikipedia.org)