Small uniformly-sized spherical particles, of micrometer dimensions, frequently labeled with radioisotopes or various reagents acting as tags or markers.
A biocompatible polymer used as a surgical suture material.
Dosage forms of a drug that act over a period of time by controlled-release processes or technology.
Relating to the size of solids.
Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.
The preparation, mixing, and assembling of a drug. (From Remington, The Science and Practice of Pharmacy, 19th ed, p1814)
A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).
Deacetylated CHITIN, a linear polysaccharide of deacetylated beta-1,4-D-glucosamine. It is used in HYDROGEL and to treat WOUNDS.
Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.
Systems for the delivery of drugs to target sites of pharmacological actions. Technologies employed include those concerning drug preparation, route of administration, site targeting, metabolism, and toxicity.
Holmium. An element of the rare earth family of metals. It has the atomic symbol Ho, atomic number 67, and atomic weight 164.93.
Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.
The application of scientific knowledge or technology to pharmacy and the pharmaceutical industry. It includes methods, techniques, and instrumentation in the manufacture, preparation, compounding, dispensing, packaging, and storing of drugs and other preparations used in diagnostic and determinative procedures, and in the treatment of patients.
A product formed from skin, white connective tissue, or bone COLLAGEN. It is used as a protein food adjuvant, plasma substitute, hemostatic, suspending agent in pharmaceutical preparations, and in the manufacturing of capsules and suppositories.
Term used to designate tetrahydroxy aldehydic acids obtained by oxidation of hexose sugars, i.e. glucuronic acid, galacturonic acid, etc. Historically, the name hexuronic acid was originally given to ascorbic acid.
A sugar acid formed by the oxidation of the C-6 carbon of GLUCOSE. In addition to being a key intermediate metabolite of the uronic acid pathway, glucuronic acid also plays a role in the detoxification of certain drugs and toxins by conjugating with them to form GLUCURONIDES.
A polymer prepared from polyvinyl acetates by replacement of the acetate groups with hydroxyl groups. It is used as a pharmaceutic aid and ophthalmic lubricant as well as in the manufacture of surface coatings artificial sponges, cosmetics, and other products.
Polymerized forms of styrene used as a biocompatible material, especially in dentistry. They are thermoplastic and are used as insulators, for injection molding and casting, as sheets, plates, rods, rigid forms and beads.
Unstable isotopes of yttrium that decay or disintegrate emitting radiation. Y atoms with atomic weights 82-88 and 90-96 are radioactive yttrium isotopes.
Hard or soft soluble containers used for the oral administration of medicine.
Salts of alginic acid that are extracted from marine kelp and used to make dental impressions and as absorbent material for surgical dressings.
Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.
The flow of BLOOD through or around an organ or region of the body.
Scandium. An element of the rare earth family of metals. It has the atomic symbol Sc, atomic number 21, and atomic weight 45.
The circulation of blood through the CORONARY VESSELS of the HEART.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Poly-2-methylpropenoic acids. Used in the manufacture of methacrylate resins and plastics in the form of pellets and granules, as absorbent for biological materials and as filters; also as biological membranes and as hydrogens. Synonyms: methylacrylate polymer; poly(methylacrylate); acrylic acid methyl ester polymer.
Usually inert substances added to a prescription in order to provide suitable consistency to the dosage form. These include binders, matrix, base or diluent in pills, tablets, creams, salves, etc.
Unstable isotopes of cerium that decay or disintegrate emitting radiation. Ce atoms with atomic weights 132-135, 137, 139, and 141-148 are radioactive cerium isotopes.
Characteristics or attributes of the outer boundaries of objects, including molecules.
A gamma-emitting radionuclide imaging agent used for the diagnosis of diseases in many tissues, particularly in cardiovascular and cerebral circulation.
Colloids formed by the combination of two immiscible liquids such as oil and water. Lipid-in-water emulsions are usually liquid, like milk or lotion. Water-in-lipid emulsions tend to be creams. The formation of emulsions may be aided by amphiphatic molecules that surround one component of the system to form MICELLES.
Isotopes that exhibit radioactivity and undergo radioactive decay. (From Grant & Hackh's Chemical Dictionary, 5th ed & McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Implants constructed of materials designed to be absorbed by the body without producing an immune response. They are usually composed of plastics and are frequently used in orthopedics and orthodontics.
A polyester used for absorbable sutures & surgical mesh, especially in ophthalmic surgery. 2-Hydroxy-propanoic acid polymer with polymerized hydroxyacetic acid, which forms 3,6-dimethyl-1,4-dioxane-dione polymer with 1,4-dioxane-2,5-dione copolymer of molecular weight about 80,000 daltons.
Condition of having pores or open spaces. This often refers to bones, bone implants, or bone cements, but can refer to the porous state of any solid substance.
Unstable isotopes of strontium that decay or disintegrate spontaneously emitting radiation. Sr 80-83, 85, and 89-95 are radioactive strontium isotopes.
A subclass of iridoid compounds that include a glycoside moiety, usually found at the C-1 position.
The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Polymers of organic acids and alcohols, with ester linkages--usually polyethylene terephthalate; can be cured into hard plastic, films or tapes, or fibers which can be woven into fabrics, meshes or velours.
A vessel that directly interconnects an artery and a vein, and that acts as a shunt to bypass the capillary bed. Not to be confused with surgical anastomosis, nor with arteriovenous fistula.
A network of cross-linked hydrophilic macromolecules used in biomedical applications.
Colloids with liquid continuous phase and solid dispersed phase; the term is used loosely also for solid-in-gas (AEROSOLS) and other colloidal systems; water-insoluble drugs may be given as suspensions.
Elimination of ENVIRONMENTAL POLLUTANTS; PESTICIDES and other waste using living organisms, usually involving intervention of environmental or sanitation engineers.
A branch of the celiac artery that distributes to the stomach, pancreas, duodenum, liver, gallbladder, and greater omentum.
Serum albumin from cows, commonly used in in vitro biological studies. (From Stedman, 25th ed)
The study of MAGNETIC PHENOMENA.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage.
Unstable isotopes of tin that decay or disintegrate emitting radiation. Sn atoms with atomic weights 108-111, 113, 120-121, 123 and 125-128 are tin radioisotopes.
Hard, amorphous, brittle, inorganic, usually transparent, polymerous silicate of basic oxides, usually potassium or sodium. It is used in the form of hard sheets, vessels, tubing, fibers, ceramics, beads, etc.
Introduction of substances into the body using a needle and syringe.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
Tablets coated with material that delays release of the medication until after they leave the stomach. (Dorland, 28th ed)
The circulation of the BLOOD through the LUNGS.
Water swollen, rigid, 3-dimensional network of cross-linked, hydrophilic macromolecules, 20-95% water. They are used in paints, printing inks, foodstuffs, pharmaceuticals, and cosmetics. (Grant & Hackh's Chemical Dictionary, 5th ed)
Maintenance of blood flow to an organ despite obstruction of a principal vessel. Blood flow is maintained through small vessels.
A spectroscopic technique in which a range of wavelengths is presented simultaneously with an interferometer and the spectrum is mathematically derived from the pattern thus obtained.
Methylester of cellulose. Methylcellulose is used as an emulsifying and suspending agent in cosmetics, pharmaceutics and the chemical industry. It is used therapeutically as a bulk laxative.
Unctuous combustible substances that are liquid or easily liquefiable on warming, and are soluble in ether but insoluble in water. Such substances, depending on their origin, are classified as animal, mineral, or vegetable oils. Depending on their behavior on heating, they are volatile or fixed. (Dorland, 28th ed)
Delivery of drugs into an artery.
A mammalian pancreatic extract composed of enzymes with protease, amylase and lipase activities. It is used as a digestant in pancreatic malfunction.
Stable cerium atoms that have the same atomic number as the element cerium, but differ in atomic weight. Ce-136, 138, and 142 are stable cerium isotopes.
Derivatives of ACETIC ACID which contain an hydroxy group attached to the methyl carbon.
The mineral component of bones and teeth; it has been used therapeutically as a prosthetic aid and in the prevention and treatment of osteoporosis.
The tendency of a gas or solute to pass from a point of higher pressure or concentration to a point of lower pressure or concentration and to distribute itself throughout the available space. Diffusion, especially FACILITATED DIFFUSION, is a major mechanism of BIOLOGICAL TRANSPORT.
Polymers of ETHYLENE OXIDE and water, and their ethers. They vary in consistency from liquid to solid depending on the molecular weight indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are NONOXYNOLS, OCTOXYNOLS, and POLOXAMERS.

5'-Nucleotidase activity of mouse peritoneal macrophages. II. Cellular distribution and effects of endocytosis. (1/3739)

The diazonium salt of sulfanilic acid (DASA) can inactivate about 80% of the total 5'-nucleotidase of viable macrophages. The remaining 20% can be inactivated if the cells are first lysed in detergent, and presumably represents an intracellular pool of 5'-nucleotidase. The bulk of this pool may represent cytoplasmic vesicles derived from plasma membrane by endocytosis. This internal compartment is expanded up to threefold immediately after the cells have ingested a large latex load. This is consistent with previous observations on the internalization of 5'-nucleotidase in latex phagosomes. In latex-filled cells this intracellular pool of enzyme is inactivated over a few hours, and the cells then slowly increase their enzyme activity to nearly normal levels. However, 24 h after latex ingestion the metabolism of 5'-nucleotidase in these recovered cells is abnormal, as the rate of enzyme degradation is about twice the normal rate, and the DASA-insensitive enzyme pool in these cells is strikingly diminished. This may reflect effects of the accumulated indigestible particles on the fate of incoming pinocytic vesicles or on newly synthesized plasma membrane precursor. Another endocytic stimulus, concanavalin A, also reduces the total cell 5'-nucleotidase activity. This effect, which is time and temperature dependent, can be prevented by the competitive sugar alpha-methyl mannose. The concanavalin A inhibition can be reversed in the absence of new protein synthesis or in cells cultivated in serum-free conditions. It is not known whether the effect of concanavalin A on 5'-nucleotidase depends upon the interiorizaiton of plasma membrane or is strictly associated with events at the cell surface.  (+info)

In vitro and in vivo activities of NS-718, a new lipid nanosphere incorporating amphotericin B, against Aspergillus fumigatus. (2/3739)

We evaluated the in vitro and in vivo potencies of a new lipid nanosphere that incorporates amphotericin B (AmB), NS-718, against Aspergillus fumigatus. The in vitro activity of NS-718 (the MIC at which 90% of strains are inhibited [MIC90], 0.25 microgram/ml) against 18 isolates of A. fumigatus was similar to that of deoxycholate AmB (D-AmB; Fungizone; MIC90, 0.25 microgram/ml), but NS-718 was more potent than liposomal AmB (L-AmB; AmBi-some; MIC90, 1.0 microgram/ml). The in vivo efficacy of NS-718 in a rat model of invasive pulmonary aspergillosis was compared with those of D-AmB and L-AmB. A low dose (1 mg/kg of body weight) of L-AmB was ineffective (survival rate, 0%), although equivalent doses of D-AmB and NS-718 were more effective (survival rate, 17%). However, a higher dose of NS-718 (3 mg/kg) was more effective (survival rate, 100%) than equivalent doses of D-AmB and L-AmB (survival rate, 0%). To explain these differences, pharmacokinetic studies showed higher concentrations of AmB in the plasma of rats treated with NS-718 than in the plasma of those treated with D-AmB. Our results suggest that NS-718, a new preparation of AmB, is a promising antifungal agent with activity against pulmonary aspergillosis.  (+info)

Quantitative study of polymer conformation and dynamics by single-particle tracking. (3/3739)

We present a new method for analyzing the dynamics of conformational fluctuations of individual flexible polymer molecules. In single-particle tracking (SPT), one end of the polymer molecule is tethered to an immobile substratum. A microsphere attached to the other end serves as an optical marker. The conformational fluctuations of the polymer molecule can be measured by optical microscopy via the motion of the microsphere. The bead-and-spring theory for polymer dynamics is further developed to account for the microsphere, and together the measurement and the theory yield quantitative information about molecular conformations and dynamics under nonperturbing conditions. Applying the method to measurements carried out on DNA molecules provides information complementary to recent studies of single DNA molecules under extensional force. Combining high precision measurements with the theoretical analysis presented here creates a powerful tool for studying conformational dynamics of biological and synthetic macromolecules at the single-molecule level.  (+info)

Adhesion energy of receptor-mediated interaction measured by elastic deformation. (4/3739)

We investigated the role of receptor binding affinity in surface adhesion. A sensitive technique was developed to measure the surface energy of receptor-mediated adhesion. The experimental system involved a functionalized elastic agarose bead resting on a functionalized glass coverslip. Attractive intersurface forces pulled the two surfaces together, deforming the bead to produce an enlarged contact area. The Johnson-Kendall-Roberts (JKR) model was used to relate the surface energy of the interaction to the elasticity of the bead and the area of contact. The surface energies for different combinations of modified surfaces in solution were obtained from reflection interference contrast microscopy (RICM) measurements of the contact area formed by the bead and the coverslip. Studies with surfaces functionalized with ligand-receptor pairs showed that the relationship between surface energy and the association constant of the ligand binding has two regimes. At low binding affinity, surface energy increased linearly with the association constant, while surface energy increased logarithmically with the association constant in the high affinity regime.  (+info)

A region of the Yersinia pseudotuberculosis invasin protein enhances integrin-mediated uptake into mammalian cells and promotes self-association. (5/3739)

Invasin allows efficient entry into mammalian cells by Yersinia pseudotuberculosis. It has been shown that the C-terminal 192 amino acids of invasin are essential for binding of beta1 integrin receptors and subsequent uptake. By analyzing the internalization of latex beads coated with invasin derivatives, an additional domain of invasin was shown to be required for efficient bacterial internalization. A monomeric derivative encompassing the C-terminal 197 amino acids was inefficient at promoting entry of latex beads, whereas dimerization of this derivative by antibody significantly increased uptake. By using the DNA-binding domain of lambda repressor as a reporter for invasin self-interaction, we have demonstrated that a region of the invasin protein located N-terminal to the cell adhesion domain of invasin is able to self-associate. Chemical cross-linking studies of purified and surface-exposed invasin proteins, and the dominant-interfering effect of a non-functional invasin derivative are consistent with the presence of a self-association domain that is located within the region of invasin that enhances bacterial uptake. We conclude that interaction of homomultimeric invasin with multiple integrins establishes tight adherence and receptor clustering, thus providing a signal for internalization.  (+info)

Effect of acute normovolemic hemodilution on distribution of blood flow and tissue oxygenation in dog skeletal muscle. (6/3739)

Acute normovolemic hemodilution (ANH) is efficient in reducing allogenic blood transfusion needs during elective surgery. Tissue oxygenation is maintained by increased cardiac output and oxygen extraction and, presumably, a more homogeneous tissue perfusion. The aim of this study was to investigate blood flow distribution and oxygenation of skeletal muscle. ANH from hematocrit of 36 +/- 3 to 20 +/- 1% was performed in 22 splenectomized, anesthetized beagles (17 analyzed) ventilated with room air. Normovolemia was confirmed by measurement of blood volume. Distribution of perfusion within skeletal muscle was determined by using radioactive microspheres. Tissue oxygen partial pressure was assessed with a polarographic platinum surface electrode. Cardiac index (3.69 +/- 0.79 vs. 4.79 +/- 0.73 l. min-1. m-2) and muscle perfusion (4.07 +/- 0.44 vs. 5.18 +/- 0.36 ml. 100 g-1. min-1) were increased at hematocrit of 20%. Oxygen delivery to skeletal muscle was reduced to 74% of baseline values (0.64 +/- 0.06 vs. 0.48 +/- 0.03 ml O2. 100 g-1. min-1). Nevertheless, tissue PO2 was preserved (27.4 +/- 1.3 vs. 29.9 +/- 1. 4 Torr). Heterogeneity of muscle perfusion (relative dispersion) was reduced after ANH (20.0 +/- 2.2 vs. 13.9 +/- 1.5%). We conclude that a more homogeneous distribution of perfusion is one mechanism for the preservation of tissue oxygenation after moderate ANH, despite reduced oxygen delivery.  (+info)

Estimation of rat muscle blood flow by microdialysis probes perfused with ethanol, [14C]ethanol, and 3H2O. (7/3739)

We used the perfused rat hindquarter to evaluate whether the microdialysis ethanol technique can be used to qualitatively estimate nutritive skeletal muscle blood flow. Four microdialysis probes were inserted in different hindlimb muscles in each of 16 rats. Hindquarters were perfused at blood flow rates ranging from 0 to 21 ml. 100 g-1. min-1. The microdialysis probes were perfused at 2 microliter/min with perfusate containing ethanol, [14C]ethanol, and 3H2O. Within and between experiments outflow-to-inflow ratios (o/i) generally varied inversely with blood flow. When a low flow or no flow was maintained in hindquarters, o/i ratios first increased with time (for at least 60 min) and then leveled off. The long time constant impaired detection of rapid oscillations in blood flow, especially at low blood flow rates. Contractions per se apparently decreased o/i ratios independent of blood flow. Ethanol and [14C]ethanol o/i ratios did not differ. 3H2O o/i paralleled ethanol and [14C]ethanol o/i ratios but it was significantly lower. In conclusion, differences in skeletal muscle blood flow can be detected by the microdialysis technique. However, the slow changes in o/i, in particular at low blood flow rates, limit the usefulness of the technique for measuring dynamic changes in blood flow; caution must also be exerted during muscle contractions. 3H2O and [14C]ethanol are good alternatives to ethanol in the determination of blood flow by microdialysis.  (+info)

DNA hybridization on microparticles: determining capture-probe density and equilibrium dissociation constants. (8/3739)

Many DNA-probe assays utilize oligonucleotide-coated microparticles for capture of complementary nucleic acids from solution. During development of these assays, as well as in other particle-based nucleic acid applications, it is useful to know both the amount of duplex formation expected under various experimental conditions and the coating density of the capture oligonucleotide on the particle surface. We examined the simplest form of a DNA-probe microparticle assay: hybridization of a particle-bound capture oligonucleotide to its solution-phase complement. Fluorescein-labeled solution-phase oligonucleotide was hybridized to varying amounts of particles, and the amount of labeled oligonucleotide remaining in solution at equilibrium was measured. We present a simple two-state, all-or-none model for bimolecular hybridization of non-self-complementary sequences that can be used to calculate the equilibrium dissociation constant ( Kd ) from hybridization data. With experimental conditions where both the Kd value and the concentration of capture probe in the reaction are small relative to the concentration of labeled complementary oligonucleotide in the reaction, density of the capture probe on the particle's surface can also be determined. Kd values for particle-based hybridization were different from those obtained from solution-phase thermodynamic parameters. At higher temperatures, hybridization on particles was more efficient than hybridization in solution.  (+info)

TY - JOUR. T1 - Simultaneous detection and quantification of six equine cytokines in plasma using a fluorescent microsphere immunoassay (FMIA). AU - Hall, SA. AU - Stucke, D. AU - Morrone, B. AU - Lebelt, D. AU - Zanella, AJ. N1 - 1023306. PY - 2015. Y1 - 2015. N2 - Cytokines are cell signalling proteins that mediate a number of different physiological responses. They are also biomarkers for inflammatory conditions and potential diagnostic references for diseases. Until recently, simultaneous quantification of cytokine profiles had not been possible. Now however, fluorescent microsphere immunoassays (FMIA) are able to measure multiple cytokines in a single sample. The following pro-inflammatory and anti inflammatory cytokines were quantified in equine plasma and serum samples: Interleukin (IL)-2, IL-4, IL-6, IL-10, Interferon (IFN)-γ, Tumor necrosis factor (TNF)-α.. AB - Cytokines are cell signalling proteins that mediate a number of different physiological responses. They are also biomarkers ...
The poly(orthoester) (POE)-poly(D,L-lactide-co-glycolide) (50:50) (PLGA) double-walled microspheres with 50% POE in weight were loaded with hydrophilic bovine serum albumin (BSA) and hydrophobic cyclosporin A (CyA). Most of the BSA and CyA was entrapped within the shell and core, respectively, because of the difference in their hydrophilicity. The morphologies and release mechanisms of proteins-loaded double-walled POE/PLGA microspheres were investigated. Scanning electron microscope studies revealed that the CyA-BSA-loaded double-walled POE/PLGA microspheres yielded a more porous surface and PLGA shell than those without BSA. The neat POE and PLGA yielded slow and incomplete CyA and BSA release. In contrast, nearly complete BSA and more than 95% CyA were released in a sustained manner from the double-walled POE/PLGA microspheres. Both the BSA- and CyA-BSA-loaded POE/PLGA microspheres yielded a sustained BSA release over 5 days. The CyA release pattern of the CyA-loaded double-walled POE/PLGA ...
Cellulose/Guar Gum Hydrogel Microspheres as a Magnetic Anticancer Drug Carrier. Yanli Li,a,b Yucheng Feng,a,b Jun Jing,a and Fei Yang *,a,b. A novel magnetic anticancer drug carrier based on cellulose, guar gum, and Fe3O4 hydrogel microspheres was synthesized by chemical crosslinking. These microspheres were crosslinked with epoxy chloropropane and loaded with 5-fluorouracil (5-fu). The effect of the ratio of cellulose to guar gum on bead size, drug loading, and in vitro release behaviors were investigated. The influence of the magnetic content on drug loading and in vitro release behaviors were also evaluated. The magnetic hydrogel microspheres were characterized via an optical microscope, Fourier transform infrared spectroscopy, swelling behavior analysis, vibrating sample magnetometer, and ultraviolet absorption spectroscopy. The results showed that as the ratio of cellulose to guar gum increased from 3:1 to 5:1, the particle size increased from 395 to 459 um. Moreover, the drug loading ...
Provided are a fluorescent microsphere comprised of a plurality of fluorescent nanocrystals embedded in a polymeric microsphere; a kit prepared from the fluorescent microspheres; and a method of producing the fluorescent microspheres comprising swelling the polymeric microsphere so that into its pores can enter fluorescent nanocrystals, and then unswelling the polymeric micropsheres so that the fluorescent nanocrystals become physically entrapped in the pores of the unswelled polymeric microsphere. Also provided is a method of using the fluorescent microspheres comprising affinity ligand for determining the presence or absence of a predetermined number of analytes in a sample by contacting the sample with the fluorescent microspheres, and detecting the fluorescence signal pattern of excited fluorescent microspheres bound to one or more analytes of the predetermined number of analytes, if present in the sample.
Abstract: Novel carbon nanotubes/activated carbon (CNTs/AC) composite microspheres were prepared by inverse emulsion polymerization, carbonization, and activation, and were applied to the adsorption of VB12, a representative of middle molecular weight toxins found in the human body. Results show that CNTs/AC composite microspheres with 70%(w) CNTs have good sphericity and their adsorption of VB12 reaches 23.59 mg·g-1, which is 5.4 and 2.7 times as much as that of activated carbon and macroporous resin, respectively. This is attributed to the more developed mesopores found in the microspheres.. Key words: CNTs, Chitosan, Composite microsphere, Adsorption ...
The in vitro controlled release kinetics of human immunoglobulin G (IgG) of different loadings from microspheres of the biodegradable polymers poly(L-lactide) (PLA) and poly(D,L-lactide-co-glycolide) (PLGA) were investigated. The microspheres were prepared by a double-emulsion technique. The release profiles exhibited an initial burst followed by a period of slow release, with PLA microspheres showing a faster rate of release than PLGA microspheres. The release rate increased with an increase in drug loading. Scanning electron microscopy (SEM) observations revealed wide differences in the morphology of microspheres made from different polymers. Drug loading had no significant effect on the morphology of the microspheres. Laser scanning confocal micrographs demonstrated a homogeneous drug distribution within the microspheres. Results from SEM and mass loss studies revealed no significant extent of polymer erosion after 50 days of release. Modeling studies within the first 50 days of incubation ...
Hollow glass microspheres made from a low heat conductivity glass composition containing a high vacuum and a thin metal coating deposited on the inner wall surface of the microspheres are described. The hollow glass microspheres are used to make superior insulation materials in the construction of highly efficient solar energy collectors. The hollow glass microspheres are made by forming a liquid film of molten glass across a coaxial blowing nozzle, applying a metal vapor blowing gas at a positive pressure on the inner surface of the glass film to blow the film and form an elongated cylinder shaped liquid film of molten glass. A transverse jet is used to direct an inert entraining fluid over and around the blowing nozzle at an angle to the axis of the blowing nozzle. The entraining fluid as it passes over and around the blowing nozzle fluid dynamically induces a pulsating or fluctuating pressure field at the opposite or lee side of the blowing nozzle in the wake or shadow of the coaxial blowing nozzle.
Fluoresbrite® carboxylate microspheres are fluorescent monodispersed polystyrene microspheres that have carboxylate groups on their surfaces which can be activated for the covalent coupling of proteins. Polysciences Fluoresbrite® particl
RNP : Recombinant RNP-68 and RNP-A antigens are bound to polystyrene microspheres, which are impregnated with fluorescent dyes to create a unique fluorescent signature. RNP antibodies, if present in diluted serum, bind to the RNP antigens on the microspheres. The microspheres are washed to remove extraneous serum proteins. Phycoerythrin (PE)-conjugated antihuman IgG antibody is then added to detect IgG anti-RNP bound to the microspheres. The microspheres are washed to remove unbound conjugate, and bound conjugate is detected by laser photometry. A primary laser reveals the fluorescent signature of each microsphere to distinguish it from microspheres that are labeled with other antigens, and a secondary laser reveals the level of PE fluorescence associated with each microsphere. Results are calculated by comparing the median fluorescence response for RNP microspheres to a 4-point calibration curve.(Package insert: Bioplex 2200 ANA Screen. Bio-Rad Laboratories, Hercules, CA 11/2011)
D=Drug, EU=Eudragit, M=Methocel. Assay methods of prepared microspheres:. Approximately 20 mg equivalent amount of Glibenclamide Microspheres was taken in a 100 ml volumetric flask and dissolved with minimum quantity of methanol. Few ml of phosphate buffer pH 7.4 was added and sonicated for 15 minutes in a sonicator to make a clear solution and made it 100 ml with phosphate buffer. Then the solution was finally filtered. Approximately 10 ml of the above solution was taken (if further dilution is necessary) in another volumetric flask and made it 100 ml with phosphate buffer. Absorbance value was determined using UV spectrophotometer at a wavelength of 242 nm. Using the absorbance value, the amount of drug entrapped was determined with the help of standard curve. Percent drug loading and drug entrapment efficiency was calculated by using the following equation. % drug Loading = (Actual drug loading / Weighed quantity of microspheres) X 100. Drug entrapment efficiency (%) = (Actual drug loading / ...
DNA vaccines or proteins are capable of inducing specific immunity; however, the translation to the clinic has generally been problematic, primarily due to the reduced magnitude of immune response and poor pharmacokinetics. Herein we demonstrate a composite microsphere formulation, composed of mesoporous silica spheres (MPS) and poly(d,l-lactide-co-glycolide) (PLGA), enables the controlled delivery of a prime-boost vaccine via the encapsulation of plasmid DNA (pDNA) and protein in different compartments. Method with modified dual-concentric-feeding needles attached to a 40 kHz ultrasonic atomizer was studied. These needles focus the flow of two different solutions, which passed through the ultrasonic atomizer. The process synthesis parameters, which are important to the scale-up of composite microspheres, were also studied. These parameters include polymer concentration, feed flowrate, and volumetric ratio of polymer and pDNA-PEI/MPS-BSA. This fabrication technique produced composite ...
The subject invention pertains to novel materials and methods for use in treating patients afflicted with oncological disorders, such as tumors. One aspect of the invention concerns methods for treating tumors comprising the administration of drug loaded pH-sensitive microspheres to a patient in need of anticancer therapy. The pH-sensitive microspheres have a swelling transition with the pH range found in or near tumor tissue. When the microspheres swell, the loaded drug is released into the microenvironment of the tumor tissue. The subject invention also pertains to novel microspheres useful in the methods of the invention. The microspheres are capable of effectively releasing a loaded substance at a pre-determined pH. The subject invention also concerns novel methods for synthesizing the microspheres of the present invention.
TY - JOUR. T1 - The organ targetability of small and large albumin microspheres containing free and HSA conjugated methotrexate. AU - Kim, Chong Kook. AU - Hwang, Sung Joo. AU - Lee, Myung Gull. PY - 1993/1/15. Y1 - 1993/1/15. N2 - The organ-targeting ability of [3H]methotrexate ([3H]MTX), [3H]MTX-human serum albumin (HSA) conjugates, and small (mean volume diameter, 10.0 μm) and large (mean volume diameter, 22.4 μm) size hydrophilic albumin microspheres (HAMs) containing different ratios of [3H]MTX-HSA conjugates to [3H]MTX was evaluated after i.v. administration of the compounds, equivalent to 150 nCi via the tail vein of mice. The total radioactivity in the lung increased immediately in a few minutes after i.v. injection of the both small and large HAMs, and then declined for up to 3-4 weeks, apparently reaching a plateau thereafter. However, the radioactivity in the liver, spleen and kidney increased slowly during the rapid decrease in radioactivity in the lung. This suggested that the ...
Page contains details about nitrogen-doped nanofibrous microsphere-based supercapacitor . It has composition images, properties, Characterization methods, synthesis, applications and reference articles : nano.nature.com
Objectives: The efficacy of rifampicin-loaded polymeric microspheres (RPLGA) delivered to guinea pigs infected with Mycobacterium tuberculosis (H37Rv) was compared with a daily dose of nebulized rifampicin suspension. Methods: Aerosol-infected animals were subjected to multiple dose or single dose treatment with RPLGA, PLGA microspheres or micronized rifampicin suspension
Magneticaly-responsive microspheres having Protein A associated with the outer surfaces thereof are reacted with antibodies selective to the cells, bacteria, or viruses to be separated from a mixed population to attach the antibodies in oriented relation with their Fab arms extending outwardly, and the microspheres are then used in a magnetic separation procedure. The preferred microspheres are prepared from a mixture of albumin, Protein A, and magnetic particles, the microspheres being prepared so that the Protein A is present in the exterior surfaces for antibody binding.
Novel magnetic-antimicrobial-fluorescent multifunctional hybrid microspheres with well-defined nanostructure were synthesized by the aid of a poly(glycidyl methacrylate) (PGMA) template. The hybrid microspheres were fully characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier transform infrared (FTIR), X-ray diffraction (XRD) and digital fluorescence microscope. The as-synthesized microspheres PGMA, amino-modified PGMA (NH2-PGMA) and magnetic PGMA (M-PGMA) have a spherical shape with a smooth surface and fine monodispersity. M-PGMA microspheres are super-paramagnetic, and their saturated magnetic field is 4.608 emu·g−1, which made M-PGMA efficiently separable from aqueous solution by an external magnetic field. After poly(haxemethylene guanidine hydrochloride) (PHGH) functionalization, the resultant microspheres exhibit excellent antibacterial performance against both Gram-positive and Gram-negative bacteria. The fluorescence feature originating from the
TY - JOUR. T1 - Focal release of neurotrophic factors by biodegradable microspheres enhance motor and sensory axonal regeneration in vitro and in vivo. AU - Santos, Daniel. AU - Giudetti, Guido. AU - Micera, Silvestro. AU - Navarro, Xavier. AU - Del Valle, Jaume. PY - 2016/4/1. Y1 - 2016/4/1. N2 - © 2016 Elsevier B.V. All rights reserved. Neurotrophic factors (NTFs) promote nerve regeneration and neuronal survival after peripheral nerve injury. However, drawbacks related with administration and bioactivity during long periods limit their therapeutic application. In this study, PLGA microspheres (MPs) were used to locally release different NTFs and evaluate whether they accelerate axonal regeneration in comparison with free NTFs or controls. ELISA, SEM, UV/visible light microscopy, organotypic cultures of DRG explants and spinal cord slices were used to characterize MP properties and the bioactivity of the released NTFs. Results of organotypic cultures showed that encapsulated NTFs maintain ...
Functional magnetic particles are formed by dissolving a mucopolysaccharide such as chitosan in acidified aqueous solution containing a mixture of ferrous chloride and ferric chloride. As the pH of the solution is raised magnetite is formed in situ in the solution by raising the pH. The dissolved chitosan is a polyelectrolyte and forms micelles surrounding the granules at pH of 8-9. The chitosan precipitates on the granules to form microspheres containing the magnetic granules. On addition of the microspheres to waste aqueous streams containing dissolved ions, the hydroxyl and amine functionality of the chitosan forms chelates binding heavy metal cations such as lead, copper, and mercury and the chelates in turn bind anions such as nitrate, fluoride, phosphate and borate.
The process of creating these beads is quite simple, according to Sathe. The surface of the beads contains a long-chain carbon molecule that makes the beads hydrophobic, meaning they repel water. The beads are dissolved in butanol and washed several times. Then the beads are counted and optical and magnetic nanocrystals are added to the suspension either simultaneously or sequentially. After 15-20 minutes, the butanol is removed to get rid of any remaining nanoparticles that didnt get incorporated into the beads and the beads are washed with ethanol. Then the beads are coated with a polymer that creates a hydrophilic surface on the beads. This allows the beads to be functionalized by adding antibodies or DNA molecules to the surface that will capture the target molecules.. These beads are dual-function -- both optical and magnetic -- but according to Sathe, more functions can be added to the beads. Adding them is as easy as adding the nanoparticles into the solution. You just have to make sure ...
The treatment of PVT-WGA SPA beads with positively charged polyethyleneimine (PEI) blocks potential non-specific binding sites on the SPA bead surface. There are two SPA bead types available with PEI treatment. The PVT-WGA-PEI type A SPA beads are treated with PEI prior to the coupling of WGA to the PVT SPA bead. The PVT-WGA PEI type B SPA beads are treated with PEI after the WGA coupling stage. The PVT-WGA-PEI type A and type B SPA beads exhibit different characteristics with regard to the non-specific binding of radiolabelled ligand directly to the SPA bead. Therefore, both bead types should be evaluated when deciding which SPA bead to use and both are included in the Select-a-Bead Kit. The binding capacity of both bead types for cell membrane protein remains 10-30 μg membrane protein per milligram of SPA bead.. SPA Scintillation beads are microspheres containing scintillant which emit light in the blue region of the visible spectrum. As a result, these beads are ideally suited to use with ...
PFH, which is a liquid at ambient temperature, is non-toxic and has been used in the preparation of multifunctional microspheres for medical and pharmaceutical applications (Giesecke & Hynynen 2003). The mechanism for the preparation of hollow microspheres takes advantage of its properties of immiscibility and volatility (Pisani et al. 2006). PFH and PMSQ were injected with appropriate flow rates under an applied voltage, in which the electrical forces acted on the driving liquid and led to the establishment of the cone. The PMSQ solution was accelerated by the electrical field, while the flow of PFH was dominated by viscous stresses. Hence, the electrical forces acting on the PMSQ film drive the inner viscous liquid so that both liquids flow steadily with the same velocity. Thus, concentric droplets can be obtained with PMSQ around the PFH; these are stable and retain their integrity owing to their immiscibility. The core material (PFH) can change phase from liquid to gas at ambient temperature ...
A Luminex (Luminex Corp., Austin, TX) multiplex swine cytokine assay was developed to measure 8 cytokines simultaneously in pig serum for use in assessment of vaccine candidates. The fluorescent microsphere immunoassay (FMIA) was tested on archived sera in a porcine reproductive and respiratory syndrome virus (PRRSV) vaccine/challenge study. This FMIA simultaneously detects innate (IL-1β, IL-8, IFN-α, TNF-α, IL-12), regulatory (IL-10), Th1 (IFN-γ) and Th2 (IL-4) cytokines. These proteins were measured to evaluate serum cytokine levels associated with vaccination strategies that provided for different levels of protective immunity against PRRSV. Pigs were vaccinated with a modified-live virus (MLV) vaccine and subsequently challenged with a non-identical PRRSV isolate (93% identity in the glycoprotein (GP5) gene). Protection (as defined by no serum viremia) was observed in the MLV vaccinated pigs after PRRSV challenge but not those vaccinated with killed virus vaccine with adjuvant (KV/ADJ) (99%
Interest in quantitative imaging of Y-90 is growing because transarterial radioembolization (RE) with Y-90 loaded microspheres is a promising and minimally invasive treatment that is FDA approved for unresectable primary and metastatic liver tumors. These cancers are a leading cause of cancer mortality and morbidity. Radioembolization is a therapy that irradiates liver tumors with radioactive microspheres administered through a microcatheter placed in the hepatic arterial vasculature. Radioembolization is based on the principle that healthy liver and tumor are mainly vascularized by the portal vein and the hepatic artery respectively. As a result, radioactive microspheres are preferentially located in the lesions after they are administered via the hepatic artery. ...
Interest in quantitative imaging of Y-90 is growing because transarterial radioembolization (RE) with Y-90 loaded microspheres is a promising and minimally invasive treatment that is FDA approved for unresectable primary and metastatic liver tumors. These cancers are a leading cause of cancer mortality and morbidity. Radioembolization is a therapy that irradiates liver tumors with radioactive microspheres administered through a microcatheter placed in the hepatic arterial vasculature. Radioembolization is based on the principle that healthy liver and tumor are mainly vascularized by the portal vein and the hepatic artery respectively. As a result, radioactive microspheres are preferentially located in the lesions after they are administered via the hepatic artery. ...
EPS puffed beads are created by applying steam to EPS resin in an enclosed chamber. The Pentane gas in each piece of resin expands from the heat causing the beads to grow by 30 to 35 times their original size. When they are fully puffed the beads are primarily made up of air. The puffed beads are then transferred to a drying chamber where they are subjected to dry air and from there into large poly bags for shipping. For very large applications the puffed beads can be blown directly into a 53 trailer.. Another major application for puffed EPS beads today is in the manufacture of bean bag chairs and poufs. Bean bag chairs, popular in the 60s, have seen resurgence in popularity in the past several years. The puffed EPS beads are sold to manufacturers in truckload quantities and blown or poured into the shells using specialized equipment.. ...
Practical design of composite materials suggests a need for an improved quantitative understanding of the interaction between acoustic waves and microspheres. In this work, we first investigate the Mie resonance of a single spherical microsphere embedded in polymer by referring to the elements of the scattering matrices. It shows that a hollow glass microsphere presents a similar monopole resonance as an air microsphere, but the resonance of a hollow glass microsphere occurs at a higher frequency with a wider bandwidth than that of an air microsphere. Then, using the multiple scattering method, we show that the low-frequency gap of a periodic array of microspheres in polymer is mainly induced by the monopole resonance of the single microsphere, and find a wide band gap under very low concentrations of the microspheres. The viscosity of the components induces the energy dissipation under the resonant scattering, and the attenuation of ultrasonic longitudinal waves in the polymer slab is dominated ...
The pH-responsive core-shell microspheres of poly(styrene-co-methylacrylic acid) (PS-co-PMAA) containing a polystyrene (PS) core and a poly(methylacrylic acid) (PMAA) shell are synthesized by one-stage soap-free copolymerization and the catalyst system palladium-iminodiacetic acid (IDA-Pd) is immobilized on the outer shell-layer of the core-shell microspheres to form the quasi-homogeneous and easily accessible catalyst PS-co-PMAA-IDA-Pd. This quasi-homogeneous PS-co-PMAA-IDA-Pd catalyst is highly dispersed in the reaction medium just like a homogeneous one and can be separated like a heterogeneous catalyst by adjusting the pH of the reaction medium. Suzuki reactions employing the quasi-homogeneous PS-co-PMAA-IDA-Pd catalyst are efficiently performed in water as the sole solvent under mild conditions such as room temperature. The PS-co-PMAA-IDA-Pd catalyst is also used in Heck reactions of a wide range of aryl halides with styrene and proves to be efficient in aqueous solution. The ...
From this point, the microspheres demagnetize and redisperse easily. This property allows efficient washing steps, low background and good reproducibility.
0008] In yet another aspect, a device is provided for producing a low-noise RF signal based on regenerating light via optical nonlinearity in an optical whispering gallery mode resonator. This device includes a laser that produces laser light at an optical pump frequency; an optical whispering gallery mode resonator that supports whispering gallery modes and exhibits optical nonlinearity to cause nonlinear optical mixing by taking energy from the laser light at the optical pump frequency to generate light at one or more new optical frequencies different from the optical pump frequency, the optical whispering gallery mode resonator exhibiting an opto-electric effect; an electrode formed on the optical whispering gallery mode resonator to apply an RF signal containing an RF frequency and one or more RF harmonics of the RF frequency to the optical whispering gallery mode resonator to cause optical modulation of light inside the optical whispering gallery mode resonator via the opto-electric effect; ...
JJ Crowley, HWL Bethall, AA Grace, A Kenny, C Wisbey, LM Shapiro; Use of Novel Stable Albumen Microspheres to Produce Enhancement of Echocardiographic Images of the Myocardium. Clin Sci (Lond) 1 February 1996; 90 (s34): 28P. doi: https://doi.org/10.1042/cs090028Pa. Download citation file:. ...
Longo W.E.; Iwata H.; Lindheimer T.A.; Goldberg E.P., 1982: Preparation of hydrophilic albumin microspheres using polymeric dispersing agents
Zepto™ Mag Ultra Blue Carboxyl Microspheres (2.5µm), 1ML (Magnetic Microspheres). 2.5µm magnetic carboxylated fluorescent beads with emission at 450nm and excitation below 435nm, 1ml.
Dev, V., Zeng, H., Forrester, J. S., Eigler, N., Tian, Y. Q., Hickey, A. J., ... Litvack, F. (1994). Microspheres for Drug-Delivery to the Arterial-Wall - A Study of Kinetics, Toxicity and Effects of Corticosteroid Loaded Microspheres. In pp. A19-A19. .. ...
A total of 47 Sprague-Dawley rats (25-35 days old) of either sex were used. Animals were subdivided into the following six groups. In group 1 (n = 6) or control, no injections were performed on the gastric walls. In group 2(n = 8), tetramethylrhodamine isothiocyanate (TRITC)-filled latex microspheres were injected into the wall of the gastric fundus. In group 3 (n = 10), TRITC-filled latex microspheres were injected into the wall of the gastric corpus. In group 4 (n = 8), TRITC-filled latex microspheres were injected into the wall of the antral/pyloric area (see below). In group 5(n = 10), double immunocytochemistry (TH and NOS) was carried out, and no injections were performed on the gastric walls. Ingroup 6 (n= 5), esophageal distension followed by double immunocytochemistry (TH and c-Fos) took place, and no injections were performed on the gastric walls. Unless otherwise specified, all rats were injected with fluorogold (Fluorochrome, Englewood, CO; 20 μg/1 ml saline/rat, ip) to label vagal ...
Molecularly imprinted microspheres comprising specific binding site are described. These microspheres can be obtained by a method comprising polymerising functional monomers and crosslinkers in a reac
Hierarchical N-doped TiO2 microspheres with exposed (001) facets [N-TiO2-(001)] were synthesized through a simple, fluorine-free solvothermal reaction with subsequent thermal treatment. The results show that the hierarchical N-TiO2-(001) microspheres are made up of numerous TiO2 nanosheets, and that isopropylamine (IPAN) acts as both the nitrogen source and the capping and shape-controlling agent that generates the high-energy (001) facets. In addition, IPAN is also effective in increasing the onset temperature of the phase transformation of TiO2 from anatase to rutile. Compared with the commercially available P25 TiO2, the as-prepared TiO2 microspheres exhibit good photocatalytic activity and high stability under visible-light irradiation. The high photocatalytic performance is derived from the synergy effect of N-doping and the separation of photogenerated electrons and holes among different facets, as evidenced by surface photovoltage spectroscopy. ...
Silver Coated Glass Microspheres work well for increasing the conductivity of bond lines, but they lack the capability to deform when compressed to give increased conductive contact between the surfaces of the bond line. These newly released Silver Coated PMMA Microspheres offer the low weight deformable pmma cores, and 250nm thick silver coating for high conductivity.. Conductivity of this product has been measured at ,0.5ohm per square with a 30% by volume preparation. Sizes available cover both the common 50 micron (45-53um) and 100 micron (90-106um) sizes and many others.. These spheres are perfect for producing anisotropic (only conductive in one direction) conductive bond lines.. Actual bond line thickness achieved will be a function of the assembly pressure and the size spheres selected.. In addition to being high conductive these silver coated PMMA is bio-compatible.. ...
What a creative alternative to power-hungry digital displays. This large outdoor billboard is totally environmentally friendly because compared to LCD and LED displays that run on electricity, this display takes no energy to run. This creative outdoor billboard is made with reflective tape, visible only when illuminated by headlights in the darkness, created by ad agency Cossette. To promote a local 24-hour McDonalds in Canada, Cossette Vancouver designed this reflective billboard thats only visible at night when cars pass by. By day, the billboard appears blank with no message, but at night, motorists driving along the highway reveal Mickey-Ds clever advertisement with their car headlights. Not only does this display save energy, it can be put anywhere, even in cities with strict requirements on flashing and lit displays.. Even though this particular display was made using reflective tape, many types of retroreflective media can be made by incorporating retroreflective microspheres in a ...
With over 35 years experience, Estapor® Microspheres is a leading brand of polymeric supports for in vitro diagnostics, life sciences, biotechnology, cosmetics, electronics and environment applications.
With over 35 years experience, Estapor® Microspheres is a leading brand of polymeric supports for in vitro diagnostics, life sciences, biotechnology, cosmetics, electronics and environment applications.
The present study investigates the feasibility of nasal delivery of ciprofloxacin microspheres formulated with various methods with acrylic acid co polymers and evaluates the mechanistic aspects of nasal route. The result based on In vitro drug release studies microspheres prepared with 3% Eudragit S100 found to be an optimized formulation. The optimized formulation released 98% of the ciprofloxacin with in 6 hrs, and found to follow Higuchi model of drug release. In near future this route of administration will become the alternative route of administration to the oral route for administering microspheres.
Lookup HS Codes for Thailand xiii 70.18.20 Glass microspheres not exceeding 1 mm in diameter. Avalara LandedCosts helps determine your duty rates and other import taxes for Thailand.
Purchase this Report (Price 2900 USD for Single-User License) at https://www.industryresearch.co/purchase/14997787. Some major points from Table of Content:. 1 Microcarrier Equipment Market Overview. 1.1 Product Overview and Scope of Microcarrier Equipment. 1.2 Microcarrier Equipment Segment by Type. 1.3 Microcarrier Equipment Segment by Application. 1.4 Global Microcarrier Equipment Market by Region. 1.4.1 Global Microcarrier Equipment Market Size Estimates and Forecasts by Region: 2020 VS 2026. 1.4.2 North America Estimates and Forecasts (2015-2026). 1.4.3 Europe Estimates and Forecasts (2015-2026). 1.4.4 China Estimates and Forecasts (2015-2026). 1.4.5 Japan Estimates and Forecasts (2015-2026). 1.5 Global Microcarrier Equipment Growth Prospects. 1.5.1 Global Microcarrier Equipment Revenue Estimates and Forecasts (2015-2026). 1.5.2 Global Microcarrier Equipment Production Capacity Estimates and Forecasts (2015-2026). 1.5.3 Global Microcarrier Equipment Production Estimates and Forecasts ...
TY - JOUR. T1 - Preparation of cross-linked chitosan microspheres by spray drying. T2 - Effect of cross-linking agent on the properties of spray dried microspheres. AU - Desai, K. G H. AU - Park, Hyun Jin. PY - 2005/6/1. Y1 - 2005/6/1. N2 - Chitosan microspheres cross-linked with three different cross-linking agents viz, tripolyphosphate (TPP), formaldehyde (FA) and gluteraldehyde (GA) have been prepared by spray drying technique. The influence of these cross-linking agents on the properties of spray dried chitosan microspheres was extensively investigated. The particle size and encapsulation efficiencies of thus prepared chitosan microspheres ranged mainly between 4.1-4.7 μm and 95.12-99.17%, respectively. Surface morphology, % erosion, % water uptake and drug release properties of the spray dried chitosan microspheres was remarkably influenced by the type (chemical or ionic) and extent (1 or 2%w/w) of cross-linking agents. Spray dried chitosan microspheres cross-linked with TPP exhibited ...
Page contains details about polydopamine-coated sulfonated polystyrene microspheres . It has composition images, properties, Characterization methods, synthesis, applications and reference articles : nano.nature.com
TY - JOUR. T1 - Detection of antibodies to West Nile virus in equine sera using microsphere immunoassay. AU - Balasuriya, Udeni B R. AU - Shi, Pei-Yong. AU - Wong, Susan J.. AU - Demarest, Valerie L.. AU - Gardner, Ian A.. AU - Hullinger, Pamela J.. AU - Ferraro, Gregory L.. AU - Boone, Joshua D.. AU - De Cino, Casey L.. AU - Glaser, Amy L.. AU - Renshaw, Randall W.. AU - Ledizet, Michel. AU - Koski, Raymond A.. AU - MacLachlan, N. James. PY - 2006/7. Y1 - 2006/7. N2 - One hundred and ninety-one sera from horses that recently were exposed to West Nile virus (WNV) by either vaccination or natural infection or that were not vaccinated and remained free of infection were used to evaluate fluorescent microsphere immunoassays (MIAs) incorporating recombinant WNV envelope protein (rE) and recombinant nonstructural proteins (rNS1, rNS3, and rNS5) for detection of equine antibodies to WNV. The rE MIA had a diagnostic sensitivity and specificity, respectively, of 99.3% and 97.4% for detection of WNV ...
Currently, there are several strategies for attaching biological ligands to polystyrene particles used as solid phase support in immunological tests and assays, including adsorption to plain polystyrene particles, covalent attachment to surface functionalized particles, and attachment of the ligand of interest to particles that are pre-coated with a binding protein such as Streptavidin, Protein A or Protein G. Fluorescent Polystyrene Particles are internally dyed, which free the surface of the beads for protein adsorption or covalent linking via functional groups.. Creative Diagnostics DiagPoly™ Fluorescent Polystyrene Particles are prepared by either incorporation of selected fluorophores into monodisperse polystyrene particles by means of swelling processes or by copolymerization of styrene with various organic fluorescent dyes, and these processes generate fluorophores labeled polystyrene particles with favorable properties, which have many advantages, such as low density, high particle ...
Currently, there are several strategies for attaching biological ligands to polystyrene particles used as solid phase support in immunological tests and assays, including adsorption to plain polystyrene particles, covalent attachment to surface functionalized particles, and attachment of the ligand of interest to particles that are pre-coated with a binding protein such as Streptavidin, Protein A or Protein G. Fluorescent Polystyrene Particles are internally dyed, which free the surface of the beads for protein adsorption or covalent linking via functional groups.. Creative Diagnostics DiagPoly™ Fluorescent Polystyrene Particles are prepared by either incorporation of selected fluorophores into monodisperse polystyrene particles by means of swelling processes or by copolymerization of styrene with various organic fluorescent dyes, and these processes generate fluorophores labeled polystyrene particles with favorable properties, which have many advantages, such as low density, high particle ...
Currently, there are several strategies for attaching biological ligands to polystyrene particles used as solid phase support in immunological tests and assays, including adsorption to plain polystyrene particles, covalent attachment to surface functionalized particles, and attachment of the ligand of interest to particles that are pre-coated with a binding protein such as Streptavidin, Protein A or Protein G. Fluorescent Polystyrene Particles are internally dyed, which free the surface of the beads for protein adsorption or covalent linking via functional groups.. Creative Diagnostics DiagPoly™ Fluorescent Polystyrene Particles are prepared by either incorporation of selected fluorophores into monodisperse polystyrene particles by means of swelling processes or by copolymerization of styrene with various organic fluorescent dyes, and these processes generate fluorophores labeled polystyrene particles with favorable properties, which have many advantages, such as low density, high particle ...
Currently, there are several strategies for attaching biological ligands to polystyrene particles used as solid phase support in immunological tests and assays, including adsorption to plain polystyrene particles, covalent attachment to surface functionalized particles, and attachment of the ligand of interest to particles that are pre-coated with a binding protein such as Streptavidin, Protein A or Protein G. Fluorescent Polystyrene Particles are internally dyed, which free the surface of the beads for protein adsorption or covalent linking via functional groups.. Creative Diagnostics DiagPoly™ Fluorescent Polystyrene Particles are prepared by either incorporation of selected fluorophores into monodisperse polystyrene particles by means of swelling processes or by copolymerization of styrene with various organic fluorescent dyes, and these processes generate fluorophores labeled polystyrene particles with favorable properties, which have many advantages, such as low density, high particle ...
Currently, there are several strategies for attaching biological ligands to polystyrene particles used as solid phase support in immunological tests and assays, including adsorption to plain polystyrene particles, covalent attachment to surface functionalized particles, and attachment of the ligand of interest to particles that are pre-coated with a binding protein such as Streptavidin, Protein A or Protein G. Fluorescent Polystyrene Particles are internally dyed, which free the surface of the beads for protein adsorption or covalent linking via functional groups.. Creative Diagnostics DiagPoly™ Fluorescent Polystyrene Particles are prepared by either incorporation of selected fluorophores into monodisperse polystyrene particles by means of swelling processes or by copolymerization of styrene with various organic fluorescent dyes, and these processes generate fluorophores labeled polystyrene particles with favorable properties, which have many advantages, such as low density, high particle ...
Currently, there are several strategies for attaching biological ligands to polystyrene particles used as solid phase support in immunological tests and assays, including adsorption to plain polystyrene particles, covalent attachment to surface functionalized particles, and attachment of the ligand of interest to particles that are pre-coated with a binding protein such as Streptavidin, Protein A or Protein G. Fluorescent Polystyrene Particles are internally dyed, which free the surface of the beads for protein adsorption or covalent linking via functional groups.. Creative Diagnostics DiagPoly™ Fluorescent Polystyrene Particles are prepared by either incorporation of selected fluorophores into monodisperse polystyrene particles by means of swelling processes or by copolymerization of styrene with various organic fluorescent dyes, and these processes generate fluorophores labeled polystyrene particles with favorable properties, which have many advantages, such as low density, high particle ...
Currently, there are several strategies for attaching biological ligands to polystyrene particles used as solid phase support in immunological tests and assays, including adsorption to plain polystyrene particles, covalent attachment to surface functionalized particles, and attachment of the ligand of interest to particles that are pre-coated with a binding protein such as Streptavidin, Protein A or Protein G. Fluorescent Polystyrene Particles are internally dyed, which free the surface of the beads for protein adsorption or covalent linking via functional groups.. Creative Diagnostics DiagPoly™ Fluorescent Polystyrene Particles are prepared by either incorporation of selected fluorophores into monodisperse polystyrene particles by means of swelling processes or by copolymerization of styrene with various organic fluorescent dyes, and these processes generate fluorophores labeled polystyrene particles with favorable properties, which have many advantages, such as low density, high particle ...
TY - JOUR. T1 - Triptorelin acetate-loaded poly(lactide-co-glycolide) (PLGA) microspheres for controlled drug delivery. AU - Park, Kyonghee. AU - Jung, Goo Young. AU - Kim, Myong Ki. AU - Park, Mork Soon. AU - Shin, Yong Kook. AU - Hwang, Jae Kwan. AU - Yuk, Soon Hong. PY - 2012/8. Y1 - 2012/8. N2 - Triptorelin acetate-loaded poly(lactide-co-glycolide) (PLGA) microspheres have been prepared in binary solvent mixtures composed of dichloromethane (DCM) and acetone (AC). The surface morphology of PLGA microspheres was examined by scanning electron microscopy with varying solvent composition, and the size distribution of PLGA microspheres was measured using a particle size analyzer. Triptorelin acetate is a luteinizing hormonereleasing hormone analog that is used as a model peptide drug. With the increase of AC content in the binary solvent mixture, PLGA microspheres with smooth surface were obtained and this led to an increased loading efficiency with the decreased particle size. For the ...
This prospective, open-label phase II study assessed the impact of liver-directed therapy with selective internal radiation therapy (SIRT) and systemic chemotherapy on progression-free survival (PFS) in liver-dominant metastatic pancreatic adenocarcinoma. Patients received yttrium-90-labelled (90Y) resin microspheres (SIR-Spheres; Sirtex Medical Limited, Sydney, Australia) as a single procedure on day 2 of the first weekly cycle of 5-fluorouracil (5FU; 600 mg/m2) with the option to switch to gemcitabine (1000 mg/m2) after 8 weeks of 5FU. Statistical analysis was conducted using Microsoft Excel (Microsoft Corporation, Redmond, Washington, USA). The primary endpoint of the study was PFS in the liver, with a median of ≥16 weeks defined as the threshold for clinical significance. PFS and overall survival (OS) were summarised by the Kaplan-Meier method using non-parametric estimates of the survivor function. Fourteen eligible patients were enrolled; ten had primary tumour in situ and eight had liver-only
In this work, [email protected] magnetic microspheres were designed and prepared by a novel strategy, and the microwave absorption properties of the materials were investigated. Four kinds of monodisperse P(MAA/St) microspheres with different carboxyl content were synthesized via facile dispersion polymerization. The Fe3O4 nanoparticles were grown on the surface of P(MAA/St) to obtain P(MAA/St)@Fe3O4 microspheres. Using P(MAA/St)@Fe3O4 as the precursors, after vacuum carbonization, [email protected] were obtained. It was observed that the carboxyl content on the microspheres’ surface increased with the increasing of MAA, which made the magnetic content and maximum specific saturation magnetization of P(MAA/St)@Fe3O4 and [email protected] increase. The obtained four kinds of [email protected] microspheres had a particle size range of 4–6 μm. The microwave absorption properties indicated that the magnetic content made a difference to the microwave absorption properties of [email protected] magnetic microspheres. The microwave absorption
Selective Internal Radiation Therapy or SIRT destroys cancer tumors with targeted radiation. Call now to learn more about this treatment- (877) 566-4660.
INTRODUCTION: Cancer is a major cause of death in cats and dogs. Tumours are often discovered by owner or veterinarian when it is too late for surgical removal. In that case a promising alternative treatment option could be internal radiation therapy by using radioactive holmium microspheres. There are two ways ... read more in which these radioactive microspheres can be administered: by interstitial microbrachytherapy (intratumoral injection) or intra-arterial microbrachytherapy (transcatheter injection). This study is divided into two substudies. SUBSTUDY 1: Holmium microspheres (HoPLLA-MS) are injected into the hepatic arteries of human livers with tumours and without tumours to examine the distribution of microspheres in these livers. This distribution is visualized by different imaging modalities (CT, SPECT, MR imaging and phosphor imaging). SUBSTUDY 2: Holmium microspheres (HoAcAc-MS and HoPLLA-MS) are used for intratumoral injection in veterinary patients with different kinds of ...
Kök FN, Wilkins RM, Cain RB, Arica MY, Alaeddinoğlu G, Hasirci V. Department of Biological Sciences, Middle East Technical University, Ankara, Turkey. Aldicarb loaded microspheres of carboxymethyl cellulose, CMC, of various compositions were prepared with the crosslinking action of Al(III). Into these microspheres, lignin was introduced as a filler to further regulate the rate of release. The encapsulation efficiency was low (4.15-13.00%) due to the high water solubility of aldicarb. Release into aqueous media was quite rapid and almost complete within 24h. Initial stages of the release (60% of AS released) was investigated to determine the release mechanism and it was found that release from the microspheres was governed by Fickian diffusion. Among the various parameters, the ratio of lignin to CMC and aldicarb to CMC were found to be influential on the rate of release from the crosslinked CMC-lignin microspheres. The soil behaviour confirmed the delayed release effect of the controlled ...
Sand column experiments were conducted to investigate the efficacy of colloidal particles (microspheres) as hydrological tracers. Two main questions were investigated: 1. What is the relationship between breakthrough volume and column height for latex microspheres in a sand column? 2. Is the fraction of latex microspheres filtered out by sand a function of column length? Small-scale sand column experiments were carried out under both saturated and unsaturated conditions. Carboxylated latex microspheres were used as test-tracers. The pore volume of water that flows out of the column before the microspheres breakthrough was linearly related to column height in all trials. The fraction of latex microspheres filtered out by the sand column was not a function of column height unless the water is salty. In one set of unsaturated experiments using 10 mM of NaCl solution, the fraction of microspheres retained in the sand column was linearly related to column height. As this was a only a proof-of-concept ...
High mobility group box 1 (HMGB1) is a family of endogenous molecules that is released by necrotic cells and causes neuronal damages by triggering inflammatory processes In the cerebral ischemic brain sustained and regulated suppression of HMGB1 has been emerged as a therapeutic means to grant neuroprotection HMGB1 consists of two HMG boxes (A and B) and an acidic C-terminal tail and the A box peptide antagonistically competes with HMGB1 for its receptors In the middle cerebral artery occlusion (MCAO) in rats a murine model of transient cerebral ischemia administration of HMGB1 A box intraparenchymally after encapsulated in biodegradable gelatin microspheres (GMS) which enhances the stability of peptide inside and allows its sustained delivery at 1 h 3 h or 6 h after MCAO reduced mean infarct volumes by respectively 81 3% 42 6% and 30 7% of the untreated MCAO-brain along with remarkable improvement of neurological deficits Furthermore the administration of HMGB1 A box/GMS suppressed ...
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This resin is functionalized with a modified Rink Amide linker and is ideal for the Fmoc SPPS of peptide amides. Cleavage from this support is achieved with 95% TFA to give peptide amides. The special properties (monosized, microspheric) recommend this resin for the use in high-speed syntheses and applications in automated sorters. ...
TY - JOUR. T1 - Measurement of bronchial blood flow with radioactive microspheres in awake sheep. AU - Wu, C. H.. AU - Lindsey, D. C.. AU - Traber, D. L.. AU - Cross, C. E.. AU - Herndon, D. N.. AU - Kramer, G. C.. PY - 1988. Y1 - 1988. N2 - Distribution of bronchial blood flow was measured in unanesthetized sheep by the use of two modifications of the microsphere reference sample technique that correct for peripheral shunting of microspheres: 1) A double microsphere method in which simultaneous left and right atrial injections of 15μm microspheres tagged with different isotopes allowed measurement of both pulmonary blood flow and shunt-corrected bronchial blood flow, and 2) a pulmonary arterial occlusion method in which left atrial injection and transient occlusion of the left pulmonary artery prevented delivery to the lung of microspheres shunted through the peripheral circulation and allowed systemic blood flow to the left lung to be measured. Both methods can be performed in unanesthetized ...
What is Selective Internal Radiation Therapy?. SIRT is a revolutionary treatment for cancers of the liver that uses new technology to deliver radiation directly to the site of the tumor. SIRT delivers millions of microscopic radioactive spheres, called SIR-Spheres or Therasphere, directly to the site of the liver tumors, where they selectively irradiate the tumors. The targeted nature of SIRT lets doctors deliver up to 40 times more radiation to the liver tumors than would be possible using conventional radiotherapy.. What to expect before, during, and after treatment. Selective Internal Radiation Therapy is known by a number of names that include: SIRT, Sir-spheres, Therasphere, radioembolization, Yttrium 90, Y90, brachytherapy, and has been coined by YES co-founder as little magic beads. We understand that being diagnosed with liver cancer or metastases to the liver from other cancer is terrifying, to say the least. Exploring the treatment options available and choosing the one best suited ...
AccessGUDID - TheraSphere Y90 Glass Microspheres 14.0 GBq (05060116920529)- TheraSphere Yttrium-90 Glass Microspheres 14.0 GBq Dose
Porous microspheres have fixed on the exterior surface thereof a coating of at least one of a perfluorinated oil, a fluorinated silicone oil or a silicone gum. The pores of the microspheres can be charged with a hydrophilic, lipophilic or perfluorinated phase. The microspheres are employed in cosmetic compositions.
Urea formaldehyde (UF) resins are important for wood industry due to their attractive properties at reasonable price. Particulate fillers added to UF are of interest with regard to improving the functionality of UF and also in terms of reduced UF consumption. To study their potential as filler, solid UF microspheres were synthesized and characterised respecting its morphology, chemical curing and thermal stability. Marigold flower structured spheres with diameters between 5 and 20 µm are presented and application trials demonstrated that high amounts of UF may be replaced by solid microspheres without impairing adhesive bond strength of solid wood bond lines. Fluorescence microscopy showed that microspheres greatly reduce adhesive penetration into the wood substrate, retaining the modified adhesive in the bondline. UF microspheres may thus be considered as viable filler for UF adhesives, particularly with regard to the possibility of endowing them with added functionality like self-healing properties.
Urea formaldehyde (UF) resins are important for wood industry due to their attractive properties at reasonable price. Particulate fillers added to UF are of interest with regard to improving the functionality of UF and also in terms of reduced UF consumption. To study their potential as filler, solid UF microspheres were synthesized and characterised respecting its morphology, chemical curing and thermal stability. Marigold flower structured spheres with diameters between 5 and 20 µm are presented and application trials demonstrated that high amounts of UF may be replaced by solid microspheres without impairing adhesive bond strength of solid wood bond lines. Fluorescence microscopy showed that microspheres greatly reduce adhesive penetration into the wood substrate, retaining the modified adhesive in the bondline. UF microspheres may thus be considered as viable filler for UF adhesives, particularly with regard to the possibility of endowing them with added functionality like self-healing properties.
Rivastigmine tartrate is an anticholine esterase inhibitor that used in the treatment of Alzheimers disease. In this study an attempt was made to encapsulate the Rivastigmine tartrate in sodium alginate microspheres for controlled delivery of it. Microspheres were prepared by the emulsion cross linking method were Glutaraldehyde saturated toluene (GST) was used as a cross linker. Total four batches were prepared with different amount of Glutaraldehyde. It was found that GST had no significant effect on % yield, also increase in amount of GST decrease the particle size and increases the entrapment. GST had shown significant effect on the in vitro drug release and found that increase in amount of GST prolongs the drug release from 36 to 96 hrs. Microspheres shown to be follow the Higuchi model.
Nanosheets-based ZnO-NiO microspheres were synthesized by a simple hydrothermal route combined with subsequent heat treatment at moderate temperature. The physical properties of the resulting samples...
Monodisperse polystyrene particles that offer a higher level of surface sulfate groups than our standard polystyrene microspheres.
Under x-ray guidance the plastic tube (catheter) is passed through the femoral arteries to be positioned in the liver arteries close to the liver tumours. Once in position, the SIR spheres® are infused through the catheter into the arteries. The SIR spheres® are prepared by Nuclear Medicine and brought to Mercy Angiography in a special Perpex box on the day of your procedure. The catheter is then connected to the Perpex box to begin infusion. The radiologists inject contrast media in between infusions to check the position of the catheter ...
Background. Stem cell therapy to improve cardiac function after myocardial infarction is hampered by poor cell retention, while it may also increase the risk of arrhythmias by providing an arrhythmogenic substrate. We previously showed that porcine adipose tissue-derived-stromal cells (pASC) induce conduction slowing through paracrine actions, whereas rat ASC (rASC) and human ASC (hASC) induce conduction slowing by direct coupling. We postulate that biomaterial microspheres mitigate the conduction slowing influence of pASC by interacting with paracrine signaling.. Aim. To investigate the modulation of ASC-loaded recombinant human collagen-based microspheres, on the electrophysiological behavior of neonatal rat ventricular myocytes (NRVM).. Method. Unipolar extracellular electrograms, derived from microelectrode arrays (8x8 electrodes) containing NRVM, co-cultured with ASC or ASC loaded microspheres, were used to determine conduction velocity (CV) and conduction heterogeneity. Conditioned medium ...
We have achieved low threshold lasing of self-assembled InAs/GaAs quantum dots coupled to the evanescent wave of the high-Q whispering gallery modes of a silica microsphere. In spite of high temperature and Q-spoiling of whispering gallery modes due to diffusion and refraction on the high index semiconductor sample, room temperature lasing is obtained with less than 100 quantum dots. This result highlights the feasibility and interest of combining self-assembled quantum dots and microspheres in view of cavity-quantum electrodynamics experiments.. ©2007 Optical Society of America. Full Article , PDF Article ...
SPA Scintillation beads are microspheres containing scintillant which emit light in the blue region of the visible spectrum. As a result, these beads are ideally suited to use with photomultiplier tube (PMT) counters such as the MicroBeta2 or TopCount.. Two types of core SPA Scintillation bead are available - yttrium silicate (YSi) and Polyvinyltoluene (PVT). PVT beads are plastic, larger in size, and stay in suspension longer than the crystalline YSi beads.. Scintillation proximity assay (SPA) is a homogeneous and versatile technology for the rapid and sensitive assay of a wide range of biological processes, including applications using enzyme and receptor targets, radioimmunoassays, and molecular interactions. When 3H, 14C, 33P, and 125I radioisotopes decay, they release β-particles (or Auger electrons, in the case of 125I). The distance these particles travel through an aqueous solution is dependent on the energy of the particle. If a radioactive molecule is held in close enough proximity to ...
SPA Scintillation beads are microspheres containing scintillant which emit light in the blue region of the visible spectrum. As a result, these beads are ideally suited to use with photomultiplier tube (PMT) counters such as the MicroBeta2 or TopCount.. Two types of core SPA Scintillation bead are available - yttrium silicate (YSi) and Polyvinyltoluene (PVT). PVT beads are plastic, larger in size, and stay in suspension longer than the crystalline YSi beads.. Scintillation proximity assay (SPA) is a homogeneous and versatile technology for the rapid and sensitive assay of a wide range of biological processes, including applications using enzyme and receptor targets, radioimmunoassays, and molecular interactions. When 3H, 14C, 33P, and 125I radioisotopes decay, they release β-particles (or Auger electrons, in the case of 125I). The distance these particles travel through an aqueous solution is dependent on the energy of the particle. If a radioactive molecule is held in close enough proximity to ...
SPA Scintillation beads are microspheres containing scintillant which emit light in the blue region of the visible spectrum. As a result, these beads are ideally suited to use with photomultiplier tube (PMT) counters such as the MicroBeta2 or TopCount.. Two types of core SPA Scintillation bead are available - yttrium silicate (YSi) and Polyvinyltoluene (PVT). PVT beads are plastic, larger in size, and stay in suspension longer than the crystalline YSi beads.. Scintillation proximity assay (SPA) is a homogeneous and versatile technology for the rapid and sensitive assay of a wide range of biological processes, including applications using enzyme and receptor targets, radioimmunoassays, and molecular interactions. When 3H, 14C, 33P, and 125I radioisotopes decay, they release β-particles (or Auger electrons, in the case of 125I). The distance these particles travel through an aqueous solution is dependent on the energy of the particle. If a radioactive molecule is held in close enough proximity to ...
Creative Diagnostics provides DiagPoly™ Fluorescent Poly(lactic-co-glycolic acid) PLGA Microspheres, Green, 30 µm, L/G=50/50 for immunoassay, bioseparation and medical imaging applications.
Creative Diagnostics provides DiagPoly™ Fluorescent Poly(lactic-co-glycolic acid) PLGA Microspheres, Green, 125 µm, L/G=50/50 for immunoassay, bioseparation and medical imaging applications.
Type I collagen peptides were prepared by hydrolysis of type I collagen protein with different enzyme combinations and this study found that the peptides obtained by papain/pepsin/trypsin combination hydrolysis were of the strongest anti-X-ray capability. The collagen peptides-carboxymethyl chitosan (CP-CMC-CaCl2) microspheres were prepared by emulsification method and used to investigate the effects on mice skin damages in vitro and in vivo. In vitro experiments indicated that the CP-CMC-CaCl2 microspheres had a protective effect on the X-ray irradiated damages of mice thymus lymphocytes. The mice skin surface texture morphological and histomorphological analysis showed a consistent result that the CP-CMC-CaCl2 microspheres played a certain role in the prevention of UV-B irradiated skin damages and could also improve ultraviolet prevention ability. Besides, the preventive function was better than its repair function. It is possible to improve the preventive function to skin photoaging and play ...
Agarose bead size in affinity chromatography - posted in Protein Expression and Purification: Hello everybody, I have a quick question regarding agarose bead size in affinity chromatography, specifically nickel-coated beads for purification of his-tagged proteins. Im using small columns (1 ml) on an FPLC. If I have a selection of the same column size with the same binding affinity, only differing in bead size (i.e. 34 µm or 165 µm), what is the advantage of smaller beads?...
TY - JOUR. T1 - Microsphere passage through intestinal circulation. T2 - via shunts or capillaries?. AU - Maxwell, L. C.. AU - Shepherd, A. P.. AU - McMahan, C. A.. PY - 1985/2. Y1 - 1985/2. N2 - Significant quantities of 9-micron microspheres (20-30%) are not trapped in the intestine following intracardiac or intra-arterial injection, but reach venous blood. Some investigators propose that the passage of 9-micron spheres measures blood flow through noncapillary connections. Because frequency distributions of intestinal capillary diameters and 9-micron spheres overlap, microspheres could simply pass through capillaries. Therefore, we developed simple probabilistic models to predict both the size distribution and the percentage of injected spheres [9 +/- 1 (SD) micron] that should appear in venous blood. Chief assumptions in models are that microsphere delivery and sphere diameter are independent and that microspheres pass through capillaries of equal or larger size. The passage predicted by the ...
"Fluorescent Microspheres" (PDF). Fluorescent Microsphere Resource Center. Archived from the original (PDF) on 2012-10-02.. ... Microspheres[edit]. Microspheres that are labeled with radioactive isotopes have been widely used since the 1960s. ... In the 1990s, methods for using fluorescent microspheres became a common substitute for radioactive particles.[9] ... Studies of the Circulation with Radioactive Microspheres., Wagner et al, Invest. Radiol., 1969. 4(6): p. 374-386. ...
"Polyethylene Microspheres , Microspheres Online". Retrieved 2020-08-20. Kemshead, JT, Ugelstad, J (1985). "Magnetic separation ... "Paramagnetic Particles , Microspheres Online". Retrieved 2020-08-20. "Fluorescent Microspheres, Microparticles and Spherical ... "Microspheres for biomedical applications: preparation of reactive and labelled microspheres", Biomaterials, 14(1):5-15. Fonnum ... Microspheres that appear to be invisible in the daylight can be illuminated to display a bright fluorescent response under UV ...
Microspheres CT MRI Nuclear medicine or NM Using radioactive microspheres is an older method of measuring perfusion than the ... "Fluorescent Microspheres" (PDF). Fluorescent Microsphere Resource Center. Archived from the original (PDF) on 2012-10-02. CS1 ... Later, techniques were developed to substitute radioactively labeled microspheres for fluorescent microspheres. The method by ... This process involves labeling microspheres with radioactive isotopes and injecting these into the test subject. Perfusion ...
Fox called these "microspheres". His protobionts were not cells, although they formed clumps and chains reminiscent of bacteria ... Proteinoid microspheres are today being considered for use in pharmaceuticals, providing microscopic biodegradable capsules in ... When present in certain concentrations in aqueous solutions, proteinoids form small microspheres. This is because some of the ... Fox thought that the microspheres may have provided a cell compartment within which organic molecules could have become ...
Cenosphere Expandable microsphere Glass microsphere Microplastics Glitter Plastic particle water pollution Arthur et al. (eds ... Colored microspheres add visual appeal to cosmetic products. When microbeads are washed down the drain, they subsequently pass ... Solid Polyethylene Microspheres for effects in color cosmetics Archived 2012-03-04 at the Wayback Machine Cosmetics and ... "Opaque Polyethylene Microspheres for Coatings Applications". Kieler, Ashlee (2015-12-29). "Say Goodbye To Microbeads: President ...
Magnetochromatic microspheres: rotating photonic crystals. Journal of the American Chemical Society, 131(43), 15687-15694. doi: ...
Microspheres are made from the addition of water or salt solution to the appropriate proteinoids. To prepare microspheres, Fox ... The microspheres were able to asexually divide via binary fission, could form junctions with other microspheres, and developed ... Microspheres have multiple properties that are similar to those of cells. The microspheres produced were mostly uniformly ... Fox says that the assembly of microspheres takes about twenty minutes and is more immediate and produces better microspheres if ...
ISBN 978-1-4244-8031-9. Bolopion, A.; Hui Xie; Haliyo, D. S.; Regnier, S. (2010). "3D haptic handling of microspheres". 2010 ...
Microspheres. Juvenum-E, Juvenum. ?. -. 1 mg ≈ 30 days Estradiol benzoate. Oil solution. Progynon-B. 25-35 mg. -. 5 mg ≈ 3-6 ... Estradiol valerate 5 mg + megestrol acetate 15 mg in an aqueous suspension of gelatin microspheres (50-80 μm)[17][15][39][24] ... Estradiol 5 mg and progesterone 100 to 300 mg in an aqueous suspension of monolithic microspheres or in a macrocrystalline ... Estradiol 5 mg + levonorgestrel 7 mg in an aqueous suspension of monolithic microspheres (80 μm) or in a macrocrystalline ...
Examples of fillers used for this purpose include hyaluronic acid; poly(methyl methacrylate) microspheres with collagen; human ...
I. Polyacrolein microspheres covalently bonded onto polyethylene". Journal of Polymer Science Part A: Polymer Chemistry. 30 (6 ... Margel, S.; Beitler, U.; Offarim, M. (1982). "Polyacrolein microspheres as a new tool in cell biology". Journal of Cell Science ... Margel earlier interests included electrochemistry of vinylic monomer and polymers, polyaldehyde microspheres and self-assembly ... Shmuel Yaroslavsky Memorial Prize for Study on the Development of Microspheres for Medical Applications, awarded by the ...
The microspheres become lodged in blood vessels surrounding the tumor and the resulting radiation damages the nearby tissue. ... 90Y has also found uses in tumor diagnosis by imaging the Bremsstrahlung radiation released by the microspheres. Positron ... "Understanding SIR-Spheres Y-90 Resin Microspheres". Colorectal Cancer Alliance. Retrieved 2019-10-21. Salem R, Gordon AC, Mouli ... Trans-arterial radioembolization is a procedure performed by interventional radiologists in which microspheres are impregnated ...
Microspheres of human albumin. *Microparticles of galactose. *Perflenapent. *Microspheres of phospholipids. *Sulfur ...
Microspheres of human albumin. *Microparticles of galactose. *Perflenapent. *Microspheres of phospholipids. *Sulfur ...
Microspheres or Beads. Once the artificial emboli have been successfully introduced, another set of DSA images are taken to ... Embolization microspheres - These are superior permanent or resorbable particulate embolic agents available in different well- ... Embolization microspheres may comprise additional functionality such as drug loading and elution capability, specific ... "Quantification and reduction of reflux during embolotherapy using an antireflux catheter and tantalum microspheres: ex vivo ...
Perflutren lipid microspheres (trade name Definity) are composed of octafluoropropane encapsulated in an outer lipid shell.[6] ... Perflexane lipid microspheres (trade name Imagent or previously Imavist) is an injectable suspension developed by Alliance ... Klibanov A.L. (1999). "Targeted delivery of gas-filled microspheres, contrast agents for ultrasound imaging". Adv Drug Deliv ... with techniques such as dual-ligand targeting of distinct receptors to polymer microspheres,[16][17] and biomimcry of the ...
Stephen Arnold (2001). "Microspheres, Photonic Atoms and the Physics of Nothing". American Scientist. 89 (5): 414-421. doi: ... S. Arnold; M. Khoshsima; I. Teraoka; S. Holler; F. Vollmer (2003). "Shift of whispering gallery modes in microspheres by ... PMID 18214098.CS1 maint: multiple names: authors list (link) Arnold Stephen (2001). "Microspheres, Photonic Atoms and the ... of Photons Orbiting within a Microsphere). He was a vising scholar at Harvard University from January until June 2013. Arnold ...
Glass microspheres, polymer microspheres, metal microspheres, and ceramic microspheres are commercially available. Solid and ... In general microspheres are solid or hollow and do not have a fluid inside, as opposed to microcapsules. Microspheres can be ... Expandable microspheres are polymer microspheres that are used as a blowing agent in e.g. puff ink, automotive underbody ... Hollow microspheres are typically used as additives to lower the density of a material. Solid microspheres have numerous ...
qiaexpressionist Lauer, Sabine A.; Nolan, John P. (2002). "Development and characterization of Ni-NTA-bearing microspheres". ...
PCL is used in the rapidly growing field of human esthetics following the recent introduction of a PCL-based microsphere dermal ... Sinha VR, Bansal K, Kaushik R, Kumria R, Trehan A (June 2004). "Poly-epsilon-caprolactone microspheres and nanospheres: an ... Bhavsar MD, Amiji MM (2008). "Development of novel biodegradable polymeric nanoparticles-in-microsphere formulation for local ...
Medina, D. D.; Goldshtein, J.; Margel, S.; Mastai, Y., Enantioselective crystallization on chiral polymeric microspheres. ...
Widder DJ, Greif WL, Widder KJ, Edelman RR, Brady TJ (February 1987). "Magnetite albumin microspheres: a new MR contrast ...
Some examples of possible syntheses are the creation of semiconductor microspheres and nanoparticles. Chemical detection is ... "The preparation of dextran microspheres in an all-aqueous system: effect of the formulation parameters on particle ... "Fabrication of conducting polyaniline microspheres using droplet microfluidics". RSC Advances. 3 (46): 24423. doi:10.1039/ ...
de Block S, de Bries C, Prinssen HM (2003). "Fatal Sepss after Uterine Artery Embolization with Microspheres". Journal of ... resulting in lengthy hospitalization for administration of intravenous antibiotics Misembolization from microspheres or ...
These microspheres are then incorporated into fiber optics. Other methods for fabricating colorimetric sensor arrays include ... One method for colorimetric sensor array fabrication involves preparation of microspheres by suspending dyes into an inert, and ... signal transduction of colorimetric data measurements in real-time of colorimetric and fluorescent data from microsphere or ...
Microspheres and electronic brachytherapy comprised the remaining 30%. One analysis predicts that the brachytherapy market may ... Microspheres and electronic brachytherapy commanded the remaining 30%. CSIntell. "Brachytherapy Market Recovery to Reach US$ ... mainly driven by the microspheres market as well as electronic brachytherapy, which is gaining significant interest worldwide ... reach over US$2.4 billion in 2030, growing by 8% annually, mainly driven by the microspheres market as well as electronic ...
The microspheres are delivered into the liver tumor through a catheter placed into the hepatic artery that supplies blood to ... The microspheres are unable to pass through the vasculature of the liver due to arteriolar capillary blockade and are trapped ... These microspheres then embolize, lodging themselves in the liver's capillaries and bathing the malignancy in high levels of ... Each milligram contains between 22,000 and 73,000 microspheres. Yttrium-90 is a pure beta emitter (physical half-life of 64.2 ...
Retrieved January 8, 2011.[dead link] "US Patent 3691140A Acrylate copolymer microspheres". Google Patents. Google Inc. ...
Shimizu, M.; K. Torigoe; I. Akazaki; T. Nakashima (2001). "Preparation of monodispersed solder microspheres by membrane ... mono dispersed polymer microspheres (for analytical column packing, enzyme carriers, liquid crystal display spacers, toner core ... "Application of porous microspheres prepared by SPG (Shirasu porous glass) emulsification as immobilizing carriers of ...
This will become a microsphere. Due to metabolic reaction, osmotic pressure will build up inside the microsphere, and this will ...
Micro.Spheres by Julius Popp takes place in a room, containing around 16 autonomously acting robots, which visitors are allowed ...
This specification covers carbon in the form of hollow microspheres. This product has been used typically as a filler material ...
Pharmaceuticals or other aldehyde reactive materials can be coupled to the microspheres. The microspheres directly form ... Microspheres of acrolein homopolymers and copolymer with hydrophillic comonomers such as methacrylic acid and/or ... The acrolein microspheres exhibited direct binding of about 7-9% by weight of antibody whereas a control HEMA-BAM microsphere ... The metal containing microspheres can be synthesized by, in situ, polymerization of the microspheres in presence of a ...
Magnetic Dipole Hydroxyethyl Methacrylate Cell Separation Magnetite Particle Magnetic Microsphere These keywords were added by ... Molday, R. S., Yen, S. P. S., and Rembaum, A., 1977, Application of magnetic microspheres in labelling and separation of cells ... Widder, K. J., Senyei, A. E., and Scarpelli, D. G., 1978, Magnetic microspheres: A model system for site specific drug delivery ... Kronick, P. L., Campbell, G. LeM., and Joseph, K., 1978, Magnetic microspheres prepared by redox polymerization used in a cell ...
On addition of the microspheres to waste aqueous streams containing dissolved ions, the hydroxyl and amine functionality of the ... The chitosan precipitates on the granules to form microspheres containing the magnetic granules. ... A method according to claim 10 in which the particles are in the form of microspheres containing from 0.1 to 90% iron and have ... A method according to claim 12 in which the microspheres contain from 1 to 25% metal and have a diameter from 500 angstroms to ...
Ceramic Microspheres White Grade W-210 are solid, engineered particles with a typical whiteness (L Value) of 90 or greater and ... What are Ceramic Microspheres? Our 3M™ Ceramic Microspheres White Grade W-210 (PDF, 452.69 Kb) are made of alkali alumino ... 3M ceramic microspheres white grade W-210 are typically chosen over other 3M ceramic microspheres for higher gloss formulations ... Ceramic microspheres have a low polymeric binder demand, meaning because of their shape and size, they do not bind with as much ...
Solar Micro-Spheres Catch 360° of Sunlight. An ingenious new solar cell design can capture the suns energy from a full 360° ... These micro-spheres are said to reach an efficiency of 20%, outpacing most flat panel designs, and can be mounted on curved ... But the latest innovation in solar technology comes in the form of spheres - micro-spheres, to be exact - which can continue to ...
Purchase Microencapsulation and Microspheres for Food Applications - 1st Edition. Print Book & E-Book. ISBN 9780128003503, ... Microencapsulation and Microspheres for Food Applications 1st Edition. 0.0 star rating Write a review ... Microencapsulation and Microspheres for Food Applications is a solid reflection on the latest developments, challenges, and ... Section I: Microcapsules and Microspheres Produced for Application in Food *Chapter 1. Microcapsules Produced from Zein *1.1 ...
MagPlex Microspheres are carboxylated polystyrene micro-particles that have been dyed into spectrally distinct sets to be ... MagPlex® Microspheres. Similar to MicroPlex® Microspheres, MagPlex® Microspheres are carboxylated polystyrene microparticles, ... MagPlex Microspheres have a maximum shelf life of five years from the date of manufacture and all MagPlex Microspheres are ... MagPlex Microspheres are available at a concentration of 2.5 million and 12.5 million beads/mL and can be ordered in one mL and ...
Microspheres, which have been optimized to reduce non-specific binding in serology assays.SeroMAP™ Microspheres are a special ... Microspheres are a special formulation of MicroPlex® Microspheres, which have been optimized to reduce non-specific binding in ... serology assays.SeroMAP™ Microspheres are a special formulation of MicroPlex™ Microspheres, which have been optimized to reduce ... formulation of MicroPlex® Microspheres, which have been optimized to reduce non-specific binding in serology assays.SeroMAP™ ...
Stainless steel microspheres including both hollow (H1) and solid ones (S1) were produced with dispersing... ... Stainless steel hollow microsphere H1 was a promising mediator for AEH for its high efficiency in heating tumor region and ... Given the same condition, heating power per unit mass was greater in hollow microsphere than solid one. Microscopic ... Stainless steel (SS) Microscaled Hollow Microsphere Magnetically induced hyperthermia (MIH) Arterial embolization hyperthermia ...
... less porous hollow microspheres can be prepared by spray-drying dispersions of film-forming solids that contain certain organic ... Method for producing protein microspheres. US5281408 *. Jan 19, 1993. Jan 25, 1994. Unger Evan C. Low density microspheres and ... Protein microspheres and methods of using them. US5723077 *. Jun 10, 1996. Mar 3, 1998. Reica Corp.. Manufacturing apparatus ... Microspheres made with just a sodium silicate and a "polysalt" may have as much as 50% difference between the bulk density and ...
Silicon microspheres enable new applications where silica microspheres fall short. Due to their semiconducting properties, new ... Experiment Figure 1. Experimental setup for silicon microsphere fabrication The silicon microspheres were created by using a ... 3, indicates that the microspheres are single crystalline. The maximum production rate was measured for this microsphere ... 2. Microsphere Formation Using an Excimer Laser The focused beam impinges onto a silicon wafer at a rate of 100 pulses per ...
M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission ...
Ceramic Microspheres White Grade W-610 are solid, engineered particles with a typical whiteness (L Value) of 90 or greater and ... What are Ceramic Microspheres? Our 3M™ Ceramic Microspheres White Grade W-610 are made of alkali alumino silicate ceramic and ... 3M ceramic microspheres white grade W-610 are typically chosen over other 3M ceramic microspheres for increased durability. ... Ceramic microspheres have a low polymeric binder demand, meaning because of their shape and size, they do not bind with as much ...
Microspheres Approved for Tumor Embolotherapy. May 18th, 2010 Aaron Rulseh Oncology, Radiology ... After being injected into a vessel supplying the tumor, the microspheres form a platelet-rich clot interrupting its blood ... One advantage of the biodegradable agent is that the microspheres degrade over time, allowing the vessel to re-canalize, ... Press release: IMBiotechnologies Receives FDA Clearance to Market Occlusin® 500 Biodegradable Microspheres in the U.S…. ...
The hollow glass microspheres are made by forming a liquid film of molten glass across a coaxial blowing nozzle, applying a ... The hollow glass microspheres are used to make superior insulation materials in the construction of highly efficient solar ... smooth hollow glass microsphere and to cool and condense the metal vapor and to deposit the metal vapor on the inner wall ... Hollow glass microspheres made from a low heat conductivity glass composition containing a high vacuum and a thin metal coating ...
This study is devoted to the synthesis and the characterization of porous metal oxide microsphere from metal loaded ion ... Those millimetric oxide microspheres incorporating uranium and americium were synthesized and characterizations showed a very ... This study is devoted to the synthesis and the characterization of porous metal oxide microsphere from metal loaded ion ... The advantage of such microsphere precursor compared to classical oxide powder is the diminution of the risk of fine ...
Patients got a total of 120 Gy of radiation in one or two doses from the glass encased microspheres, which Salem said did not ...
These microspheres can be obtained by a method comprising polymerising functional monomers and crosslinkers in a reac ... Molecularly imprinted microspheres comprising specific binding site are described. ... The microspheres are finally dried in vacuo. The reference (control) microspheres are prepared and treated in exactly the same ... Molecularly imprinted microspheres comprising specific binding site are described. These microspheres can be obtained by a ...
These microspheres expand when heated, producing many applications. Because they have unknown biological persistence and ... Expancel microspheres are thermoplastic microspheres enclosing hydrocarbon. These microspheres expand when heated, producing ... Expanded, but not unexpanded microspheres, also caused eosinophilic bronchitis and bronchiolitis, mucous metaplasia of airways ... By histopathology, both unexpanded and expanded microspheres caused granulomatous bronchopneumonia characterized by macrophages ...
microsphere synonyms, microsphere pronunciation, microsphere translation, English dictionary definition of microsphere. n a ... microsphere. Also found in: Medical, Encyclopedia, Wikipedia. microsphere. (ˈmaɪkrəʊˌsfɪə) n. a very small medical particle, ... BSA microsphere sizes are approximately 80 [micro]m for all samples.. Cross-linked bovine serum albumin microspheres prepared ... We were successful with large microspheres in initial trials and need to bring down the microsphere size for the proposed use ...
Metal-Coated Hollow Ceramic Microspheres,p,Accumet Materials Co.. Thermoplastic Microspheres. Ceramic Grinding Beads. Masonry ...
... chitosan microspheres were prepared by a suspension cross-linking technique. A petroleum ether/mineral oil mixture was used as ... 5-fluorouracil loaded chitosan microspheres for chemoembolization J Microencapsul. Nov-Dec 1999;16(6):741-9. doi: 10.1080/ ... It was possible to load the chitosan microspheres with 5-FU to a concentration of 10.4 mg 5-FU/g chitosan. Around 60% of the ... Smaller microspheres with narrower size distributions were obtained when the chitosan/solvent ratio and drug/chitosan ratio ...
Existing customers who want to order Microspheres by EDI, web, phone, or fax: ... New customers who want to order Microspheres or make a price inquiry: ...
The ceramic microspheres formed by various sol gel techniques are characterized by having: A. at least one metal oxide phase; ... said microspheres being solid, transparent, non-vitreous, ceramic particles which serve as lens elements in the retroreflective ... Pavement marking comprising ceramic microspheres held by a binder, ... SiO2 microspheres made by a thermal fusion process were obtained. These microspheres as well as the sol gel microspheres had a ...
Microspheres Could Save Patients Whose Lungs Have Stopped Working. Doctors could eventually use the method to quickly reverse ... Kheirs oxygen-filled microspheres, reported today in Science Translational Medicine, are around three micrometers in diameter ... The team is also working on making the microspheres more stable, with the ultimate goal of creating an off-the-shelf solution ... Kheir says that more lab animal work is needed to explore the clinical utility of the microsphere technology, which he and some ...
... for isolating specific antibody hybridomas from a hybridoma cell mixture employing antigen-conjugated labeled microspheres and ... but only 0.4 C.BPC-101 microspheres, and the anti-Ig-1b line binds 21 C.BPC-101 microspheres but only 0.2GPC-8 microspheres. ... was coupled to the microspheres, indicating about 25,000 IgG molecules per microsphere. The microspheres were dispersed by ... followed by separating bound microspheres from unbound microspheres;. selectively segregating by means of said microsphere ...
In vitro experiments indicated that the CP-CMC-CaCl2 microspheres had a protective effect on the X-ray irradiated damages of ... Keywords: CARBOXYMETHYL CHITOSAN; COLLAGEN PEPTIDES; HISTOLOGICAL ANALYSIS; IRRADIATION RESISTANCE; MICROSPHERES Document Type: ... The collagen peptides-carboxymethyl chitosan (CP-CMC-CaCl2) microspheres were prepared by emulsification method and used to ... function to skin photoaging and play a better effectiveness of cosmetic skin care by adding the CP-CMC-CaCl2 microspheres into ...
divided by the amount of microspheres . The could be obtained via filtration and distillation after the PU shells were ... Use of Novel Polyurethane Microspheres in a Curcumin Delivery System. Yongmei Hu,1 Qingshan Li,1 Wei Hong,2 Guangzhong Xing,1 ... J. F. Zhang, Q. Tang, X. Y. Xu, and N. Li, "Development and evaluation of a novel phytosome-loaded chitosan microsphere system ... Using these parameters, the microspheres were prepared and characterized with variations in . The effect of this variation on ...
  • 4. A composition according to claim 1 in which the particles are in the form of chitosan microspheres containing a dispersion of magnetite granules. (google.co.uk)
  • 12. A method according to claim 10 in which the particles are in the form of microspheres containing from 0.1 to 90% iron and have a diameter from 100 angstroms to 1000 microns. (google.co.uk)
  • More particularly, the present invention relates to easily recoverable, functional magnetic microspheres comprising magnetic particles which are coated with a glucosamine polysaccharide such as chitosan, and to a method for forming the microspheres. (google.co.uk)
  • 3M™ Ceramic Microspheres White Grade W-210 are solid, engineered particles with a typical whiteness (L Value) of 90 or greater and an effective d90 particle size of 12 μm. (3m.com)
  • A reproducible process to quickly fabricate uniform microsphere particles with a narrow distribution of diameters and high yield is presented in this paper. (slideshare.net)
  • Pavement marking comprising ceramic microspheres held by a binder, said microspheres being solid, transparent, non-vitreous, ceramic particles which serve as lens elements in the retroreflective pavement markings. (google.ca)
  • Glass microspheres can be scratched or chipped by grit and dirt particles on the highway. (google.ca)
  • Kheir's oxygen-filled microspheres, reported today in Science Translational Medicine, are around three micrometers in diameter and are diluted in a solution commonly used in transfusions so that the particles can flow through even small capillaries in the body. (technologyreview.com)
  • Rat alveolar macrophages and IgG-opsonized and non-opsonized polystyrene microspheres were used as model macrophages and drug delivery particles. (nih.gov)
  • The microscopic particles are sphere shaped, due to this, in the ceramic microsphere production it only fewer quantity of resin. (pr.com)
  • In addition to microspheres and nanocrystals, we also are a leading provider of magnetic particles. (thermofisher.com)
  • Our Dynospheres® microspheres are monodisperse, unstained polystyrene particles, ranging in size from about 1 μm to about 30 μm in diameter. (thermofisher.com)
  • Our IDC microspheres are ultraclean, surfactant-free polystyrene particles that range in diameter from about 20 nm to about 5 μm. (thermofisher.com)
  • All of these particles can be customized with respect to diameter, density (very small microspheres, below 1 μm in diameter, can be designed to remain in suspension indefinitely), surface charge density, type of surface group, and other properties. (thermofisher.com)
  • We offer a broad range of Molecular Probes® fluorescent particles, including our FluoSpheres® microspheres, each containing an individual fluorescent dye to meet your desired combination of excitation and emission wavelength maxima, intensity, and CV. (thermofisher.com)
  • Meet the newest addition to our family of magnetic particles-Magnefy™ ~1µm carboxylated superparamagnetic microspheres. (bangslabs.com)
  • To provide a useful tool for studying the mechanisms of retention and translocation of respirable-sized, alpha-emitting particles, we have developed a method of incorporating {sup 244}Cm into fluorescent polystyrene latex microspheres. (osti.gov)
  • misc{etde_20547778, title = {Production and testing of {sup 244}Cm-labeled fluorescent polystyrene latex microspheres} author = {Guilmette, R A, Mueller, H L, and Brodbeck, R D} abstractNote = {To provide a useful tool for studying the mechanisms of retention and translocation of respirable-sized, alpha-emitting particles, we have developed a method of incorporating {sup 244}Cm into fluorescent polystyrene latex microspheres. (osti.gov)
  • We report here for the first time efficient transfection of mdx mice myofibers with dystrophin gene constructs delivered in vivo by the microsphere particles MF-2. (nature.com)
  • High preferential intranuclei incorporation of gene-loaded microsphere particles was observed. (nature.com)
  • A single-screw design for incorporating iM30K microspheres into thermoplastic resins should contain a dispersive mixing element, which typically serves to break up agglomerates of fine particles. (ptonline.com)
  • Microspheres are spherically shaped particles within the size range of 1-1000 μm in diameter. (diva-portal.org)
  • Several strategies have been developed to circumvent the limitations of curcumin, including encapsulation in liposomes, biodegradable microspheres, cyclodextrin, hydrogels, polymeric nanoparticles, and lipid-based nanoparticles [ 9 ]. (hindawi.com)
  • and a method of producing the fluorescent microspheres comprising swelling the polymeric microsphere so that into its pores. (google.es)
  • and a method of producing the fluorescent microspheres comprising swelling the polymeric microsphere so that into its pores can enter fluorescent nanocrystals, and then unswelling the polymeric micropsheres so that the fluorescent nanocrystals become physically entrapped in the pores of the unswelled polymeric microsphere. (google.es)
  • 1. A fluorescent microsphere comprised of a plurality of fluorescent nanocrystals physically entrapped in a polymeric microsphere, wherein the fluorescent nanocrystals are functionalized with a plurality of molecules selected from the group consisting of carboxylic acid, diaminocarboxylic acid, monoaminocarboxylic acid, and a combination thereof. (google.es)
  • 2. The fluorescent microsphere according to claim 1 , wherein the polymeric microsphere comprises multiple molecules of reactive functionality comprising a free chemical group. (google.es)
  • 3. The fluorescent microsphere according to claim 1 , wherein physically entrapped in the polymeric microsphere is a homogenous population of fluorescent nanocrystals. (google.es)
  • 11. The fluorescent microsphere according to claim 1 , wherein the polymeric micro6sphere further comprises carbon black in a weight percentage of from about 0.5 to about 5. (google.es)
  • 12. The fluorescent microsphere according to claim 1 , wherein the polymeric microsphere comprises a combination of a polymeric material and a magnetic material selected from the group consisting of a polymeric material into which is embedded the magnetic material, a magnetic material core and a polymeric material coating, a polymeric material coating over the magnetic layer, and a magnetic material dispersed within a polymeric material. (google.es)
  • Role of particle size in phagocytosis of polymeric microspheres. (nih.gov)
  • Polymeric microspheres are extensively researched for applications in drug and vaccine delivery. (nih.gov)
  • Professor Bai Yang, director of the The Key Laboratory for Supramolecular Structure and Materials of Ministry of Education at Jilin University/PR China, and his group have developed a number of methods to organize polymeric, inorganic, even composite microspheres into various structures, generating various properties and functions. (nanotech-now.com)
  • Aerosols of biodegradable polymeric microspheres containing antitubercular agents may be delivered to the lungs to improve the treatment of tuberculosis. (rti.org)
  • DUALITE ® U products are heat expandable polymeric microspheres that posses a wide range of performance characteristics with applicability to a broad spectrum of end uses. (chasecorp.com)
  • Glass microspheres have been used as low-density fillers for various kinds of polymeric compounds since the mid-1960s. (ptonline.com)
  • The pavement marking industry has long desired transparent, solid microspheres or beads that would be useful as brighter and more durable retroreflective lens elements in pavement markings. (google.ca)
  • Based on the type, market is segmented into hollow and solid microspheres. (sbwire.com)
  • The application of solid microspheres depends on their size and construction. (grandviewresearch.com)
  • Microspheres are also used in composites to fill polymer resins for specific characteristics such as weight, sandability and sealing surfaces. (wikipedia.org)
  • 4. A method according to claim 1, wherein said microspheres are organic polymer microspheres of from about 0.1 to 2 micrometer diameter having fluorescent chromophore functionalities having excitation at greater than 450 nm. (google.es)
  • CeloNova's Embozene(TM) Microspheres consist of a hydrogel core and an exterior shell made from Polyzene®-F, CeloNova's proprietary polymer which is known to be anti-inflammatory and bacterial-resistant. (medgadget.com)
  • From the outset, we took a different approach to developing our Embozene(TM) Microspheres by asking physicians and medical scientists for the qualities and characteristics that the ideal embolic device should have," said Thomas A. Gordy, President and Chief Executive Officer, CeloNova BioSciences, Inc. "Then, we engineered Embozene(TM) Microspheres to have those properties, which are made even better with Polyzene®-F, our proprietary polymer. (medgadget.com)
  • We have used a long-acting nitric oxide (NO)-releasing polymer to develop injectable biodegradable microspheres capable of localized NO release over prolonged periods of time. (nih.gov)
  • Referred to as super-absorbent polymer (SAP) microspheres, QuadraSphere Microspheres are packaged dry, but once exposed to aqueous-based media, they swell to approximately 4x the size printed on the product label. (merit.com)
  • It includes many small and big chemical and material companies who provide raw materials such as glass, ceramic, polymer, and other chemicals involved in the manufacture of microspheres. (marketsandmarkets.com)
  • Protein bioactivity and polymer orientation is affected by stabilizer incorporation for double-walled microspheres. (nih.gov)
  • The consequences of AOT on protein bioactivity are also assessed and provide strong implications for the importance of appropriate stabilizer analysis in future studies involving drug co-encapsulates in polymer based microsphere systems. (nih.gov)
  • The Global Polymer Microspheres Market is poised to grow strong during the forecast period 2017 to 2027. (reportlinker.com)
  • Fluorescent polymer microspheres are available in four standard volumes: 1mL, 5mL, 10mL, and 100mL. (bangslabs.com)
  • The most common types are solid and hollow glass or polymer microspheres, as well as ceramic. (cosmeticsandtoiletries.com)
  • Glass, polymer and ceramic microspheres are well-known in the cosmetics and personal care industry for advantages such as sensorial benefits and optical effects, among others. (cosmeticsandtoiletries.com)
  • A line of colored, solid polyethylene microspheres was recently developed a via a proprietary process to produce polymer microspheres that are smooth, highly spherical, non-soluble in water and most solvents, and that withstand temperatures of up to 100°C. These spheres can be manufactured with specific gravities from 0.96 g/cc to 1.3 g/cc, which provides for optimal suspension in a solution. (cosmeticsandtoiletries.com)
  • Solid polymer microspheres incorporate pigments and additives to achieve colorful fillers that serve multiple functions in a cosmetic formula by acting as colorant, opacifier and texture enhancer simultaneously. (cosmeticsandtoiletries.com)
  • Herein, macroporous polymer microspheres were fabricated, and further functionalized by polyoxometalate. (rsc.org)
  • Although the S60HS microspheres have found some injection molding applications, the higher strength and smaller size of the newest iM30K grade provide polymer composites with much better physical and mechanical properties while at the same time offering better crush survivability when processed by extrusion or injection molding or other high-shear processes. (ptonline.com)
  • Microspheres were characterised by Fourier transform infrared (FTIR) spectroscopy and differential scanning calorimetry (DSC) to confirm the absence of chemical interactions between drug and polymer and to know the formation of microspheres structure. (unboundmedicine.com)
  • On the basis of raw material, the global microspheres market is segmented intoglass, fly ash, ceramic, polymer and metallic component. (sbwire.com)
  • Microspheres industry is also characterized by continuous research and development activities in the polymer industry. (grandviewresearch.com)
  • Glass, ceramic, polymer, fly ash and metallic are the materials used for producing microspheres. (grandviewresearch.com)
  • In this study, chitosan microspheres were prepared by a suspension cross-linking technique. (nih.gov)
  • The size and size distribution of the chitosan microspheres varied in the size range of 100-200 microns, by changing the emulsifier concentration, stirring rate, chitosan/solvent ratio and drug/chitosan solution ratio. (nih.gov)
  • It was possible to load the chitosan microspheres with 5-FU to a concentration of 10.4 mg 5-FU/g chitosan. (nih.gov)
  • Effect of collagen peptides-carboxymethyl chitosan microspheres o. (ingentaconnect.com)
  • This study aimed to research the preparation and content determination of capsaicin-chitosan microspheres (CCMS) enteric coated tablets. (mdpi.com)
  • Su, Z.-Q. The Preparation of Capsaicin-Chitosan Microspheres (CCMS) Enteric Coated Tablets. (mdpi.com)
  • Chen J, Huang G-D, Tan S-R, Guo J, Su Z-Q. The Preparation of Capsaicin-Chitosan Microspheres (CCMS) Enteric Coated Tablets. (mdpi.com)
  • Aceclofenac, a NSAID, was successfully encapsulated into chitosan microspheres. (unboundmedicine.com)
  • Eudragit coated chitosan microspheres prevented the release of the aceclofenac in the physiological environment of the stomach and small intestine and released 95.9±0.34% in the colon. (unboundmedicine.com)
  • The findings of the present study conclusively state that chitosan microspheres are promising for colon targeting of aceclofenac to synchronise with chronobiological symptoms of rheumatoid arthritis. (unboundmedicine.com)
  • QuiremSpheres® is based on Holmium-166 microspheres, which were developed in the clinic as an alternative to Yttrium-90 microspheres for treating unresectable liver tumors with selective internal radiation therapy (SIRT). (terumo-europe.com)
  • Microsphere treatment is based on the concept of selective internal radiation therapy (SIRT), a technique that minimizes the risk of nontargeted radiation by delivering radiation doses directly to the tumor site, utilizing a tumor's own hypervascularity. (fortherecordmag.com)
  • Sirtex's expansion into Latin America is a pivotal step in our strategy to bring the SIR-Spheres microspheres treatment to more patients who will benefit from this technology," said Michael Mangano, president of Sirtex Medical Inc. "In the past, patients with inoperable liver tumors in Latin America have had few options and Selective Internal Radiation Therapy (SIRT) has not been available. (mdtmag.com)
  • About Selective Internal Radiation Therapy using SIR-Spheres microspheres Selective Internal Radiation Therapy (SIRT), also known as radioembolization, is a proven technology for inoperable liver cancer that delivers doses of radiation directly to the site of tumors. (mdtmag.com)
  • Seza A. Gulec, M.D., F.A.C.S., director of the Goshen Cancer Institute Hepatic Oncology Program at Goshen Health System, and Yuman Fong, M.D., chief of gastric and mixed tumor service at Memorial Sloan Kettering Cancer Center, partnered to discuss the basic concepts involved in development of Yttrium 90 (Y-90) microsphere Selective Internal Radiation Therapy (SIRT) and review clinical data pertaining to its application. (redorbit.com)
  • Due to their smaller particle size, 3M ceramic microspheres white grade W-210 are typically chosen over other 3M ceramic microspheres for higher gloss formulations. (3m.com)
  • 31. A method according to claim 1, wherein a desired size of the microspheres is achieved by controlling the nucleation and particle growth process. (freepatentsonline.com)
  • 33. A method according to claim 31, wherein the control of the nucleation and particle growth process is intended to avoid aggregation of the microspheres. (freepatentsonline.com)
  • 1. A pavement marking comprising ceramic microspheres held by a binder said microspheres being solid, transparent, non-vitreous microspheres having an average particle size of up to 125 micrometers, comprising zirconia and silica, and containing at most only minor amounts of titanium dioxide. (google.ca)
  • 7. A coating composition comprising a mixture of binder material and ceramic microspheres which are solid, transparent, non-vitreous microspheres having an average particle size of up to 125 micrometers and which are comprised of zirconia and silica and contain at most only minor amounts of titania. (google.ca)
  • 6. The fluorescent microsphere according to claim 1 , wherein the fluorescent nanocrystals have an average particle size of approximately 1 nm to approximately 20 nm. (google.es)
  • The basic process of manufacturing glass microspheres consists of extracting glass at high temperature from soda lime borosilicate and then milling it to fine particle size, following which the fine powder is mixed with trace amounts of sulfur containing compounds such as sodium sulfate. (prweb.com)
  • Ceramic microspheres are single, semi-transparent fine particle size high-strength ceramic microspheres. (pr.com)
  • COMPEL™ are highly uniform superparamagnetic microspheres ideal for applications that demand uniform particle response. (bangslabs.com)
  • The quality of the microspheres ranges from monodispersed microspheres produced under tight specifications, to microsphere grades with variations in particle size and sphere uniformity. (cosmeticsandtoiletries.com)
  • Transmission spectrum of microsphere biosensor without particle attachment [17]. (intechopen.com)
  • The microspheres were evaluated for particle size, encapsulation efficiency, drug loading capacity, mucoadhesion studies, stability studies, in vitro and in vivo drug release studies. (unboundmedicine.com)
  • The collagen peptides-carboxymethyl chitosan (CP-CMC-CaCl 2 ) microspheres were prepared by emulsification method and used to investigate the effects on mice skin damages in vitro and in vivo . (ingentaconnect.com)
  • In vitro experiments indicated that the CP-CMC-CaCl 2 microspheres had a protective effect on the X-ray irradiated damages of mice thymus lymphocytes. (ingentaconnect.com)
  • NO-releasing microspheres were incubated in physiologic buffer, and in vitro NO release was measured using a Griess assay. (nih.gov)
  • Under physiologic conditions in vitro, microspheres continued NO release for up to 4 weeks. (nih.gov)
  • This study also highlighted the challenge in finding manufacturing assays that even enable comparative evaluation of in vitro drug release profiles for establishing equivalence among various microsphere formulations. (pharmamanufacturing.com)
  • As a result of the coating the permeability of the copolymer-GO hybrid microspheres was reduced to an extent that suppressed the initial burst release and enabled sustained drug release in in vitro testing. (rsc.org)
  • Effect of stirring rate on size distribution, effect of albumin concentration, effect of cross linking agent on microspheres were the parameters investigated Angle of repose, drug content, in vitro and in vivo release rate studies were also carried out. (ijpsonline.com)
  • In vitro release profile for formulations containing metronidazole-loaded albumin microspheres with cross linking agent shows slow sustained release up to 24 h.lt also obeys first order kinetics. (ijpsonline.com)
  • The purpose of this research was to test the hypothesis that starch-entrapped microspheres would produce favourable fermentation profiles and microbial shifts during in vitro fermentation with the faecal microbiota from patients with inflammatory bowel disease (IBD). (cambridge.org)
  • Human bone marrow mesenchymal stromal cells (BMSCs) and rabbit implant models were used to test the bioactivity of the microspheres in vitro and in vivo, respectively. (medworm.com)
  • Also provided is a method of using the fluorescent microspheres comprising affinity ligand for determining the presence or absence of a predetermined number of analytes in a sample by contacting the sample with the fluorescent microspheres, and detecting the fluorescence signal pattern of excited fluorescent microspheres bound to one or more analytes of the predetermined number of analytes, if present in the sample. (google.es)
  • 5. The fluorescent microsphere according to claim 2 , further comprising affinity ligand operably bound thereto. (google.es)
  • 7. The fluorescent microsphere according to claim 1 , wherein the fluorescent nanocrystals comprise semiconductor nanocrystals. (google.es)
  • 9. The fluorescent microsphere according to claim 1 , wherein the fluorescent nanocrystals comprise doped metal oxide nanocrystals. (google.es)
  • 10. The fluorescent microsphere according to claim 9 , wherein the fluorescent microsphere is magnetic. (google.es)
  • 13. The fluorescent microsphere according to claim 3 , wherein the homogenous population of fluorescent nanocrystals, when excited with an excitation light source, emit a fluorescence signal pattern observable as a single color. (google.es)
  • 14. The fluorescent microsphere according to claim 4 , wherein the heterogeneous population of fluorescent nanocrystals, when excited with an excitation light source, emit a fluorescence signal pattern observable as more than one color. (google.es)
  • 15. The fluorescent microsphere according to claim 14 , wherein the fluorescence signal pattern comprises multicolor fluorescence and detectably distinguishable intensities. (google.es)
  • We use our proprietary fluorescent dyes and incorporate our stains internally, making our fluorescent microspheres the brightest available . (thermofisher.com)
  • Our patented FocalCheck ™ fluorescent microspheres are specifically designed for examining the alignment, sensitivity, and stability of confocal laser-scanning microscopes. (thermofisher.com)
  • Focal alignment is also possible simultaneously in three colors by aligning the green orange and dark red rings of the FocalCheck™ microspheres containing fluorescent green orange dark red ring stains. (thermofisher.com)
  • To ensure no migration, microspheres were fluorescently tagged and injected into the corpus cavernosum of adult rats, and fluorescent imaging was performed weekly for 4 weeks, at which point rats were sacrificed. (nih.gov)
  • Our MultiSpeck™ and TetraSpeck™ microspheres contain multiple fluorescent dyes, each exciting and emitting at distinct wavelengths in the same bead, which can be used to calibrate multiplexed imaging assays. (thermofisher.com)
  • Fluorescent microspheres are a mainstay in diagnostics and life sciences research, finding use as fluorescent markers, assay substrates, and instrument standards. (bangslabs.com)
  • In order to meet the unique performance criteria required of microparticles in these different applications, Bangs stocks an extensive array of fluorescent microspheres. (bangslabs.com)
  • Guilmette, R A, Mueller, H L, and Brodbeck, R D. Production and testing of {sup 244}Cm-labeled fluorescent polystyrene latex microspheres. (osti.gov)
  • Solid polyethylene microspheres can also be manufactured in most colors, including flesh tone, clear, gray, fluorescent (see Figure 2 ), glow-in-the-dark and multicolor, among others, which suggests several options for color effects as well as an array of color-matching possibilities (see Figure 3 ). (cosmeticsandtoiletries.com)
  • Microencapsulation and Microspheres for Food Applications is a solid reflection on the latest developments, challenges, and opportunities in this highly expanding field. (elsevier.com)
  • Microencapsulation And Microspheres For Food Applications, Book by Leonard M.c. (indigo.ca)
  • The chitosan precipitates on the granules to form microspheres containing the magnetic granules. (google.co.uk)
  • Currently, the typical methods used to form microspheres include forcing molten silicon out of a nozzle [10] or melting the end of a fiber [1]. (slideshare.net)
  • An oily matrix was used as a CH vehicle and to form microspheres, as well as an alginate outer coating, aiding in the slow release of ions. (umich.edu)
  • Silicon microspheres enable new applications where silica microspheres fall short. (slideshare.net)
  • We demonstrate the quality factor Q = (0.8 ± 0.1) × 10 10 of whispering-gallery modes in fused-silica microspheres at 633 nm, close to the ultimate level determined by fundamental material attenuation as measured in optical fibers. (osapublishing.org)
  • In a minimally invasive treatment, millions of radioactive SIR-Spheres microspheres are infused via a catheter into the liver where they selectively target liver tumors with a dose of internal radiation up to 40 times higher than conventional radiotherapy, while sparing healthy tissue. (mdtmag.com)
  • This radioactive tracer is a low energy tracer which imitates the high energy radioactive SIR-Spheres microspheres. (thelondonclinic.co.uk)
  • In contrast, alveolar macrophage activation, polymorphonuclear leukocytes, LDH and albumin in bronchoalveolar laveage fluid were initially elevated but returned to near control levels at 28 days, and did not reflect the persistent granulomatous bronchopneumonia caused by Expancel microspheres. (cdc.gov)
  • A sterile non-pyrogenic suspension of microspheres of human serum albumin with the stable, high-molecular-weight fluorocarbon gas perflutren, used as a contrast enhancement agent for ultrasound procedures. (cancer.gov)
  • The albumin microspheres sonicated preparation contains very small gas-filled albumin microspheres that reflect the sound waves and help create a better picture. (mayoclinic.org)
  • British Library EThOS: Development and pharmacology of mitomycin C albumin microspheres. (bl.uk)
  • Various formulations of metronidazole loaded albumin microspheres were prepared by heat stabilization process and chemical stabilization process. (ijpsonline.com)
  • Hence albumin microspheres prepared by the heat stabilization process and chemical stabilization process could be used for the treatment of hepatic amoebiasis where the sustained action is needed. (ijpsonline.com)
  • This performance additive, called iM30K, is said to be the first hollow glass microsphere capable of withstanding injection molding and extrusion pressures of 30,000 psi. (thefreedictionary.com)
  • Hollow glass microspheres Improve flow properties Hollow glass microsphere is a tiny sphere with high ball-type rate. (bushorchimp.com)
  • We will share best practices to troubleshoot antibody conjugation to AnteoBind™ activated Estapor® europium microspheres in assay development and the initial scale-up procedure. (sigmaaldrich.com)
  • CeloNova BioSciences out of Newnan, Georgia has received FDA clearance for the firm's Embozene Color-Advanced Microspheres for treatment of hypervascularized tumors. (medgadget.com)
  • Embosphere Microspheres are indicated for use in embolization of arteriovenous malformations, hypervascular tumors, symptomatic uterine fibroids, and the prostate arteries for relief of symptoms related to Benign Prostatic Hyperplasia (BPH). (merit.com)
  • The HEPAR study is aimed at determining the safety of radioactive holmium containing microspheres for the treatment of tumors in the liver. (clinicaltrials.gov)
  • Sirtex's SIR-Spheres ® microspheres are now available to treat inoperable liver tumors in Argentina. (mdtmag.com)
  • 1 "The radioactive microspheres are a powerful resource for treating unresectable primary and secondary tumors," said Dr. Ricardo García-Mónaco, Head of Angiography and Endovascular Therapy, Hospital Italiano de Buenos Aires. (mdtmag.com)
  • Internal radiation therapy, also called (90)Y radioembolization ((90)Y-RE), consists in delivering implantable microspheres labeled with (90)Y into the arteries that feed liver tumors in order to provide a high dose of radiation to tumor nodules irrespective of their number, size and location, while preserving the non-tumoral liver tissue from receiving a harmful level of radiation. (cun.es)
  • Keywords: excimer, MDR, microcavity, microsphere, resonators, silicon photonics, WGM I. Introduction The need for low-cost photonic devices has stimulated a significant amount of research in silicon photonics. (slideshare.net)
  • The experimentally measured quality factors are limited by the sensitivity of the experimental setup, however, the microsphere quality factor is several orders of magnitude higher than current micro-ring resonators. (slideshare.net)
  • Microspheres made of high quality optical glass, can be produced for research on the field of optical resonators or cavities. (wikipedia.org)
  • In recent years, many temperature sensing devices based on microsphere resonators have emerged, attracting an increasing research interest. (mdpi.com)
  • For the purpose of this review article, microsphere resonators are divided according to their constituting materials, namely silicone, silica, compound glass, and liquid droplet. (mdpi.com)
  • Wang, P. Temperature Sensing Performance of Microsphere Resonators. (mdpi.com)
  • Yu J, Lewis E, Brambilla G, Wang P. Temperature Sensing Performance of Microsphere Resonators. (mdpi.com)
  • Several years ago, microspheres gained [FDA] approval for the treatment of metastatic colorectal cancer. (fortherecordmag.com)
  • Clinical studies have confirmed that patients with metastatic colorectal cancer treated with SIR-Spheres microspheres have response rates higher than with other forms of treatment, resulting in increased life expectancy, greater periods without tumor activity and improved quality of life. (mdtmag.com)
  • 1Sirtex Medical Inc.'s SIR-Spheresà ® microspheres are indicated for the treatment of non-resectable metastatic colorectal cancer in combination with intra-arterial FUDR chemotherapy. (redorbit.com)
  • The report " Polyurethane (PU) Microspheres Market by Applications (Encapsulation, Coatings, Adhesives, and Cosmetics) - Global Trends & Forecasts to 2020" , The global Polyurethane (PU) microspheres market is projected to reach USD 74.4 Million by 2020 from USD 47.6 Million in 2014, growing at a CAGR of 7.8% from 2015 to 2020. (marketsandmarkets.com)
  • The hybrid microspheres showed improved drug encapsulation by 46.4% which was attributed to the diffusion barrier properties and π-conjugated structure of GO. (rsc.org)
  • Approximately 90 physicians in the United States use Sirtex's SIR-Spheres microspheres in more than 86 medical centers. (redorbit.com)
  • Hollow glass microspheres made from a low heat conductivity glass composition containing a high vacuum and a thin metal coating deposited on the inner wall surface of the microspheres are described. (google.ca)
  • These materials are high-strength, low-density hollow glass microspheres made from soda-lime borosilicate glass. (imcdgroup.com)
  • 142 Pages Report] The Global Microspheres Market size was valued USD 3.98 Billion in 2016 and is projected to reach USD 6.68 Billion by 2022, at a CAGR of 9.02% between 2017 and 2022. (marketsandmarkets.com)
  • This report categorizes the global microspheres market based on type, application, and region. (marketsandmarkets.com)
  • Pune, India -- ( SBWIRE ) -- 01/18/2018 -- The Global Microspheres Market accounted to USD 840.1 Millionin 2016 and is projected to grow at a CAGR of 7.8% during the forecast period of 2017 to 2024.e upcoming market report contains data for historic year 2015, the base year of calculation is 2016 and the forecast period is 2017 to 2024. (sbwire.com)
  • On the basis of geography, global microspheres market report covers data points for 28 countries across multiple geographies namely North America & South America, Europe, Asia-Pacific, and Middle East & Africa. (sbwire.com)
  • The global microspheres market is consolidated due to the presence of limited number of players concentrated in few countries. (sbwire.com)
  • Some of the major players operating in global microspheres market are 3M, AkzoNobel N.V., Sigmund Lindner GmbH, Potters Industries LLC, Luminex Corporation, Momentive, Chase Corporation, Cospheric LLC and TrelleborgABamong others. (sbwire.com)
  • The global microspheres market size was valued at USD 3.2 billion in 2015 and is expected to grow at a CAGR of 10.4% over the forecast period. (grandviewresearch.com)
  • com)-- A new report has been added to the database of the Market Research Hub (MRH), titled "Global Ceramic Microsphere Industry 2016, Trends and Forecast Report. (thefreedictionary.com)
  • The ceramic microsphere industry report is a professional and in-depth research report on the regional market conditions of the Ceramic Microsphere industry, focusing on the key regions including North America, Europe and Asia. (pr.com)
  • Then research estimates 2016-2021 market development trends of ceramic microsphere industry for the future growth. (pr.com)
  • This study examines the safety and efficacy of transarterial chemoembolization using doxorubicin-loaded 30-60 µm QuadraSphere microspheres (DEM-TACE) for the treatment of hepatocellular carcinoma. (dovepress.com)
  • Treatment of hepatocellular carcinoma by radioembolization using 90Y microspheres. (cun.es)
  • Radiologic-pathologic correlation of hepatocellular carcinoma treated with internal radiation using yttrium-90 microspheres. (biomedsearch.com)
  • According to the research, growing fiberglass demand is higher due to its durability, light-weighted and non-corrosive components in construction industry which is projected to increase ceramic microspheres demand during forecast period of 2016-2020. (pr.com)
  • Stainless steel hollow microsphere H1 was a promising mediator for AEH for its high efficiency in heating tumor region and killing cancer cells as well as good biocompatibility. (springer.com)
  • After being injected into a vessel supplying the tumor, the microspheres form a platelet-rich clot interrupting its blood supply. (medgadget.com)
  • Radioembolization with 166 Ho microspheres induced a tumor response with an acceptable toxicity profile in patients with liver metastases. (terumo-europe.com)
  • Embosphere Microspheres are available in six size ranges to allow physicians to target the microvasculature of the tumor and shut down the feeder network while maintaining patency of the major artery feeding the organ. (merit.com)
  • Given the known risk of recurrence in patients with persistent tumor enhancement after UAE, it is concluded that tris-acryl gelatin microspheres should be the preferred agent for UAE at this time. (merit.com)
  • Angiographies of hypervascularized tumor pre- and post-embolization illustrate the ability of QuadraSphere Microspheres to perform a targeted embolization. (merit.com)
  • That's when the microspheres are injected through the catheter and into the tumor blood supply," explains Wahab, who uses the TheraSphere product. (fortherecordmag.com)
  • The blood carries the microspheres to the tumor area of greatest vascularity where they become trapped. (fortherecordmag.com)
  • TheraSphere glass microspheres take advantage of a tumor's hypervascularity and prioritize microsphere flow to the tumor. (bostonscientific.com)
  • Because TheraSphere has high activity per sphere, fewer microspheres are needed to achieve the desired dose. (bostonscientific.com)
  • The report "Polymethyl Methacrylate (PMMA) Microspheres Market by Application (Displays, Coatings, Cosmetics, Medical, 3D Printing Inks, and Films), & Size (0 To 30 Microns, Above 30 Microns) - Global Forecast to 2020" , The global PMMA microsphere market is projected to reach USD 191.7 Million by 2020 from USD 118.1 Million in 2014, at a CAGR of 8.5% during the period 2015 to 2020. (pitchengine.com)
  • Formulators may be able to extend resin in their formulation by adding 3M ceramic microspheres and potentially reduce cost. (3m.com)
  • SeroMAP™ Microspheres are a special formulation of MicroPlex® Microspheres , which have been optimized to reduce non-specific binding in serology assays. (luminexcorp.com)
  • The great innovation in this field relies on the formulation of microspheres and nanoparticles to encapsulate the peptide in order to enhance its bioavailability and therapeutic efficacy. (bachem.com)
  • To discover more on how Bachem is part of this technology in achieving successful formulation of APIs, please join our webinar on the benefits and challenges of microspheres and nanoparticles for peptide delivery. (bachem.com)
  • Its prominent role in the treatment paradigm is largely attributed to improved compliance with treatment derived from the administration of the long-acting, injectable PLGA microsphere formulation every two weeks in a physician's office - compared with self-administration of the oral formulation on a daily or every-other-day basis. (pharmamanufacturing.com)
  • Sodium depletion has also allowed hollow glass microspheres to be used in chemically sensitive resin systems, such as long pot life epoxies or non-blown polyurethane composites Additional functionalities, such as silane coatings, are commonly added to the surface of hollow glass microspheres to increase the matrix/microspheres interfacial strength (the common failure point when stressed in a tensile manner). (wikipedia.org)
  • This study is devoted to the synthesis and the characterization of porous metal oxide microsphere from metal loaded ion exchange resin. (springer.com)
  • Their application concerns the fabrication of uranium-americium oxide pellets using the powder-free process called Calcined Resin Microsphere Pelletization (CRMP). (springer.com)
  • 4. The pavement marking of claim 1 which comprises sheeting having a binder film wherein the binder is a thermoplastic resin containing the ceramic microspheres both within the body of the binder and exposed at the sheeting surface. (google.ca)
  • By using fewer quantity of resin, it involves low budget which invites makers to use ceramic microspheres as an alternative for non-soluble extracts in process of paints & coatings production. (pr.com)
  • In single-screw extruders, the iM30K microspheres should be added at a downstream feed port after the resin has been melted, just before the beginning of the metering zone, to minimize potential breakage of the spheres. (ptonline.com)
  • The glass microspheres within the molten resin are apt to break when exposed to excessive injection speed and pressure. (ptonline.com)
  • Microspheres are resin spheres that each contains millions of radioactive atoms, or 'beads' (yttrium-90). (thelondonclinic.co.uk)
  • Similar to MicroPlex® Microspheres , MagPlex® Microspheres are carboxylated polystyrene microparticles, or "beads," that have been dyed into spectrally distinct sets, or "regions," allowing them to be individually identified by an xMAP® instrument . (luminexcorp.com)
  • MagPlex Microspheres are available at a concentration of 2.5 million and 12.5 million beads/mL and can be ordered in one mL and four mL vial sizes. (luminexcorp.com)
  • Similar to MicroPlex Microspheres, these beads are carboxylated polystyrene microparticles that have been color coded into 100 spectrally distinct sets, or "regions. (luminexcorp.com)
  • SeroMAP Microspheres are available at a concentration of 12.5 million beads/mL and are only available in a 4 mL vial size. (luminexcorp.com)
  • The beads are not free of surfactant and contain surface carboxylic acid groups at higher concentration than the standard Polybead Polystyrene Carboxylate Microspheres. (polysciences.com)
  • Microspheres are glass beads bonded with Yttrium 90 [Y-90], an isotope that emits beta radiation," explains T. Clark Gamblin, MD, an assistant professor of surgery at the University of Pittsburgh School of Medicine, where the devices are being put to clinical use. (fortherecordmag.com)
  • Also known as spheres, balls, beads or micro-balloons, microspheres are manufactured from a variety of raw materials. (cosmeticsandtoiletries.com)
  • Poly(lactide-co-glycolide) (PLGA) microspheres containing rifampicin were prepared using solvent evaporation and spray drying methods. (rti.org)
  • Respirable rifampicin loaded PLGA microspheres were produced by both solvent evaporation and spray drying methods. (rti.org)
  • Portland, OR -- ( SBWIRE ) -- 08/01/2017 -- The methods used for the preparation of microspheres include spray drying, solvent evaporation, single emulsion technique, double emulsion technique, phase separation concertation technique, spray drying and spray congealing, solvent extraction, quassi emulsion solvent diffusion. (sbwire.com)
  • To address this, through solvent extraction (EMS), solvent evaporation (SMS) and cosolvent methods (CMS), we prepared three types of PLGA microspheres with various internal structures, but similar size distribution. (medworm.com)
  • During this minimally invasive procedure, millions of radioactive microspheres are placed in the liver via a catheter infusion. (fortherecordmag.com)
  • The measurement of dye absorption with the suspension inside the integrating sphere detector required a correction for dye fluorescence which yielded an estimate of the microsphere fluorescence quantum yield. (thefreedictionary.com)
  • Temperature monitoring relies mainly on the thermo-optic/thermal expansion of the microspheres and on the fluorescence of the doped ions. (mdpi.com)
  • Microsphere Technology coats borosilicate glass microspheres and aluminosilicate ceramic cenospheres with coatings based on metals, metal oxides, pigments, and dyes. (thefreedictionary.com)
  • 5. A composition according to claim 1 in which the microspheres contain from 1 to 25% metal and have a diameter from 500 angstroms to 1 micron. (google.co.uk)
  • Glass microspheres are usually between 1 and 1000 micrometers in diameter, although the sizes can range from 100 nanometers to 5 millimeters in diameter. (wikipedia.org)
  • A measurable enhancement of the backscattered light in the visible range was obtained when a gold nanoparticle was placed inside the photonic nanojet region produced by a dielectric microsphere with a 4.4 μm diameter. (wikipedia.org)
  • Because they have unknown biological persistence and toxicity, we investigated the toxicity of two unexpanded (11.1 and 15.4 m mean diameter) and two expanded (3.1 and 5.5 m mass median aerodynamic diameter) Expancel microspheres in intratracheally-instilled, male, Sprague-Dawley rats. (cdc.gov)
  • Embosphere Microspheres exhibit a consistent cross-sectional diameter for targeted delivery. (merit.com)
  • The in vivo median diameter of occluded arteries is significantly different between sizes of QuadraSphere Microspheres,* providing targeted occlusion. (merit.com)
  • Glass microspheres are spheres of glass, between 1 to 1000 micrometers in diameter, manufactured for a wide variety of uses in the research, medicine, and consumer goods industries, among others. (prweb.com)
  • Microsphere refers to a spherical microparticle between 1 and 1,000 microns (μm) in diameter (see Figure 1 ). (cosmeticsandtoiletries.com)
  • Extrusion from a syringe is influenced by the paste's viscosity, drying time, microsphere diameter and gel strength of the carrier phase. (europa.eu)
  • Glass microspheres are microscopic spheres of glass manufactured for a wide variety of uses in research, medicine, consumer goods and various industries. (wikipedia.org)
  • The Asia-Pacific Glass Microspheres Market report defines and segments the glass microspheres market in Asia-Pacific with analysis and forecast of revenue. (prweb.com)
  • Increasing demand in other applications such as cosmetics & personal care, oil & gas, and life science is expected to boost the growth of microsphere market during the forecast period. (sbwire.com)
  • Hollow microsphere segment is expected to register high growth rate during the forecast period. (sbwire.com)
  • Growing need for advanced drug delivery systems and drug carriers is expected to be a major factor for the growth of microspheres over the forecast period. (grandviewresearch.com)
  • PLA/PLGA microspheres have been incorporated into a multitude of pharmaceutical products used for the treatment of a wide array of indications, including cancer, psychiatric disorders, endocrine disorders and periodontal disease. (pharmamanufacturing.com)
  • The complexity of manufacturing PLA/PLGA microspheres creates a similar challenge when planning to develop new extended-release therapies or generic versions of branded products. (pharmamanufacturing.com)
  • Uniform-sized insulin-loaded PLGA microspheres for improved early-stage peri-implant bone regeneration. (medworm.com)
  • Unlike embolic microspheres currently on the market that remain in the patient's body for life, OCL 500 microspheres are designed to completely biodegrade over time. (businesswire.com)
  • There are several advantages to MagPlex Microspheres over traditional MicroPlex Microspheres . (luminexcorp.com)
  • A use of nanojets produced by transparent microspheres in order to excite optical active materials, under upconversion processes with different numbers of excitation photons, has been analyzed as well. (wikipedia.org)
  • This invention relates to the field of pavement markings containing transparent microspheres for reflectorizing the markings. (google.ca)
  • The transparent microspheres now most widely used for pavement markings are made of certain glasses, which are amorphous vitreous materials. (google.ca)
  • We can prepare unstained, colored, magnetic and fluorescently stained polystyrene microspheres for a variety of industrial and research applications. (thermofisher.com)
  • In this study, novel polyurethane microspheres containing curcumin (Cur-PUMs) were prepared using carboxymethyl cellulose sodium to improve the bioavailability and prolong the retention time of curcumin. (hindawi.com)
  • Polyurethane microspheres finds its largest application as an encapsulating agent for various end use industries which include pharmaceutical, paints & coating, and agro chemical industries. (marketsandmarkets.com)
  • Advantages such as coating with uniform thickness without defects or thick edges drives the demand of polyurethane microspheres in the paints & coatings industry. (marketsandmarkets.com)
  • Controlled release of chemicals of interest from encapsulants increases the effectiveness of delivery which drives the demand of polyurethane microspheres in the pharmaceutical and agrochemical industries. (marketsandmarkets.com)
  • Lead product, OCL 500 embolization microspheres is the first biodegradable embolic agent cleared by the US FDA. (businesswire.com)
  • Just a small amount of spacer grade monodisperse microspheres can create a controlled gap, as well as define and maintain specified bond line thickness. (wikipedia.org)
  • 35. A method according to claim 1, wherein the reaction conditions are controlled so that the microspheres become monodisperse. (freepatentsonline.com)
  • Pulmonary toxicity of Expancel microspheres in the rat. (cdc.gov)
  • Expancel microspheres are thermoplastic microspheres enclosing hydrocarbon. (cdc.gov)
  • These findings emphasize the importance of histopathology for evaluating pulmonary toxicity, suggest that Expancel microspheres are a potential occupational hazard, and indicate a need for additional studies on their potential pulmonary toxicity. (cdc.gov)
  • AkzoNobel is opening a new Expancel microsphere production line within its paint and coatings complex in Jundiai, Sao Paulo State, with the aim of serving both the Brazilian and regional market demand. (thefreedictionary.com)
  • Engineering hydrogel microspheres for healthy and tasty foods 8. (indigo.ca)
  • The microsphere/hydrogel paste was cured by UV light before transfer. (europa.eu)
  • Thermo Fisher Scientific, through its legacy IDC, Dynal, Molecular Probes, and Quantum Dot Corporation businesses, is an industry-leading provider of microspheres and nanocrystals for commercial use, with more than 35 years of expertise. (thermofisher.com)
  • Embozene(TM) Microspheres are precisely calibrated, they retain their shape after passing through a catheter, and they can stay in suspension for an extended time. (medgadget.com)
  • The hydrophilic surface and spherical shape of Embosphere Microspheres prevent aggregation in the catheter lumen and vasculature. (merit.com)
  • These microspheres will be administered by infusion in the liver artery using a arterial catheter in the femoral artery. (clinicaltrials.gov)
  • Microspheres are then administered through the catheter and travel along the hepatic artery and into the small blood vessels located around the tumour surface as shown in the figure below. (thelondonclinic.co.uk)
  • We were successful with large microspheres in initial trials and need to bring down the microsphere size for the proposed use in tissue engineering for the TMJ, especiallyfor use with the animal models for early stage (rabbit) and pre-clinical studies (pig) beyond my project scope. (thefreedictionary.com)
  • Kheir says that more lab animal work is needed to explore the clinical utility of the microsphere technology, which he and some of the study coauthors are patenting. (technologyreview.com)
  • Flexion has successfully used this technology to produce clinical trial microsphere product for its lead drug candidate FX006, which has been tested in more than 200 patients. (biospace.com)
  • The growth of the market is largely attributed toward the increasing demand for flat panel display, architectural coatings, and medical applications in which PMMA microspheres are majorly used. (pitchengine.com)
  • These microspheres are used in formulators for paints & coatings because of higher viscidness, Shrinkage, reduced costs and volatile organic compounds emissions. (pr.com)
  • The European region is a major consumer for wood coatings, architectural coatings, and plastic coatings for automotive underbody coatings, and hence commands the major share of the PU microspheres market by value. (marketsandmarkets.com)
  • Industry players like 3M, AkzoNobel are investing and conducting advanced research in the field of microspheres to support end-use industries such healthcare and coatings and others. (grandviewresearch.com)
  • The size of above 30 microns facilitates medical procedures such as cell sorting and immunoprecipitation, thus making these microspheres suitable for medical research and biological laboratory experiments. (pitchengine.com)
  • Major value is added during the manufacturing process, where a great amount of effort and expertise, mainly in terms of balancing the ingredients is required to manufacture microspheres suitable for different applications. (marketsandmarkets.com)
  • Our non-functionalized microspheres are suitable for coating via adsorption. (bangslabs.com)
  • Therefore, DOX-linker-Fbg microspheres could be a suitable drug carrier for safer and effective drug delivery. (dovepress.com)