OrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesInformation ScienceHealth Care
Microbial Sensitivity TestsSulfamethoxazoleSensitivity and SpecificityAnti-Bacterial AgentsTrimethoprimDrug Resistance, MicrobialAntitubercular AgentsCulture MediaBacteriological TechniquesMethodsBacteriaReproducibility of ResultsParasitic Sensitivity TestsContrast SensitivityPredictive Value of TestsInsulin ResistanceROC CurveTime FactorsMultiple Chemical SensitivityMutationSensory ThresholdsReagent Kits, DiagnosticInsulinPolymerase Chain ReactionMolecular Sequence DataDose-Response Relationship, DrugFalse Positive Reactions
Microbial Sensitivity Tests
Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
Sulfamethoxazole
A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Anti-Bacterial Agents
Substances that reduce the growth or reproduction of BACTERIA.
Trimethoprim
A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
Drug Resistance, Microbial
The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).
Antitubercular Agents
Drugs used in the treatment of tuberculosis. They are divided into two main classes: "first-line" agents, those with the greatest efficacy and acceptable degrees of toxicity used successfully in the great majority of cases; and "second-line" drugs used in drug-resistant cases or those in which some other patient-related condition has compromised the effectiveness of primary therapy.
Culture Media
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
Bacteriological Techniques
Techniques used in studying bacteria.
Methods
A series of steps taken in order to conduct research.
Bacteria
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
Reproducibility of Results
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Parasitic Sensitivity Tests
Tests that demonstrate the relative effectiveness of chemotherapeutic agents against specific parasites.
Contrast Sensitivity
The ability to detect sharp boundaries (stimuli) and to detect slight changes in luminance at regions without distinct contours. Psychophysical measurements of this visual function are used to evaluate visual acuity and to detect eye disease.
Predictive Value of Tests
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Insulin Resistance
Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
ROC Curve
A graphic means for assessing the ability of a screening test to discriminate between healthy and diseased persons; may also be used in other studies, e.g., distinguishing stimuli responses as to a faint stimuli or nonstimuli.
Time Factors
Elements of limited time intervals, contributing to particular results or situations.
Multiple Chemical Sensitivity
An acquired disorder characterized by recurrent symptoms, referable to multiple organ systems, occurring in response to demonstrable exposure to many chemically unrelated compounds at doses below those established in the general population to cause harmful effects. (Cullen MR. The worker with multiple chemical sensitivities: an overview. Occup Med 1987;2(4):655-61)
Mutation
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
Sensory Thresholds
The minimum amount of stimulus energy necessary to elicit a sensory response.
Reagent Kits, Diagnostic
Commercially prepared reagent sets, with accessory devices, containing all of the major components and literature necessary to perform one or more designated diagnostic tests or procedures. They may be for laboratory or personal use.
Insulin
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
Polymerase Chain Reaction
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Dose-Response Relationship, Drug
The relationship between the dose of an administered drug and the response of the organism to the drug.
False Positive Reactions
Positive test results in subjects who do not possess the attribute for which the test is conducted. The labeling of healthy persons as diseased when screening in the detection of disease. (Last, A Dictionary of Epidemiology, 2d ed)

Effect of a staphylococcin on Neisseria gonorrhoeae. (1/26286)

Phage group 2 staphylococcal strain UT0002 contains a large 56S virulence plasmid with genes that code for both exfoliative toxin and a specific staphylococcin termed Bac R(1). Four penicillinase-producing strains and three penicillin-susceptible strains of Neisseria gonorrhoeae were killed by Bac R(1). After 30 min of growth of the penicillin-resistant TR1 strain in 62.5 arbitrary units of Bac R(1) per ml, loss of viability was approximately 90%, and, after 5 h, an approximately 99.99% loss of viability was observed. Lysis did not accompany cell death, and 84% of the Bac R(1) added to the growth medium was adsorbed to the gonococcal cells. The extracellular supernatant fluid from a substrain of staphylococcal strain UT0002 cured of the plasmid for Bac R(1) production had no lethal effect on the gonococcal strains. Bac R(1) was also shown to have bactericidal activity against an L-form of N. meningitidis, indicating that the outer envelope of a neisserial cell is not needed for bacteriocin activity. Ten different normal human sera were unable to neutralize Bac R(1) activity. The bacteriocin lacks adsorption specificity. It binds to but does not kill Escherichia coli cells, indicating that the cell envelope of gram-negative organisms can provide protection against the staphylococcin.  (+info)

UK-18892, a new aminoglycoside: an in vitro study. (2/26286)

UK-18892 is a new aminoglycoside antibiotic, a derivative of kanamycin A structurally related to amikacin. It was found to be active against a wide range of pathogenic bacteria, including many gentamicin-resistant strains. The spectrum and degree of activity of UK-18892 were similar to those of amikacin, and differences were relatively minor. UK-18892 was about twice as active as amikacin against gentamicin-susceptible strains of Pseudomonas aeruginosa. Both amikacin and UK-18892 were equally active against gentamicin-resistant strains of P. aeruginosa. There were no appreciable differences in the activity of UK-18892 and amikacin against Enterobacteriaceae and Staphylococcus aureus. Cross-resistance between these two antimicrobials was also apparent.  (+info)

Emergence of vancomycin resistance in Staphylococcus aureus. Glycopeptide-Intermediate Staphylococcus aureus Working Group. (3/26286)

BACKGROUND: Since the emergence of methicillin-resistant Staphylococcus aureus, the glycopeptide vancomycin has been the only uniformly effective treatment for staphylococcal infections. In 1997, two infections due to S. aureus with reduced susceptibility to vancomycin were identified in the United States. METHODS: We investigated the two patients with infections due to S. aureus with intermediate resistance to glycopeptides, as defined by a minimal inhibitory concentration of vancomycin of 8 to 16 microg per milliliter. To assess the carriage and transmission of these strains of S. aureus, we cultured samples from the patients and their contacts and evaluated the isolates. RESULTS: The first patient was a 59-year-old man in Michigan with diabetes mellitus and chronic renal failure. Peritonitis due to S. aureus with intermediate resistance to glycopeptides developed after 18 weeks of vancomycin treatment for recurrent methicillin-resistant S. aureus peritonitis associated with dialysis. The removal of the peritoneal catheter plus treatment with rifampin and trimethoprim-sulfamethoxazole eradicated the infection. The second patient was a 66-year-old man with diabetes in New Jersey. A bloodstream infection due to S. aureus with intermediate resistance to glycopeptides developed after 18 weeks of vancomycin treatment for recurrent methicillin-resistant S. aureus bacteremia. This infection was eradicated with vancomycin, gentamicin, and rifampin. Both patients died. The glycopeptide-intermediate S. aureus isolates differed by two bands on pulsed-field gel electrophoresis. On electron microscopy, the isolates from the infected patients had thicker extracellular matrixes than control methicillin-resistant S. aureus isolates. No carriage was documented among 177 contacts of the two patients. CONCLUSIONS: The emergence of S. aureus with intermediate resistance to glycopeptides emphasizes the importance of the prudent use of antibiotics, the laboratory capacity to identify resistant strains, and the use of infection-control precautions to prevent transmission.  (+info)

Acinetobacter bacteremia in Hong Kong: prospective study and review. (4/26286)

The epidemiological characteristics of 18 patients with acinetobacter bacteremia were analyzed. Patients (mean age, 55.5 years) developed bacteremia after an average of 14.1 days of hospitalization. Fifteen of 16 patients survived bacteremia caused by Acinetobacter baumannii. Cultures of blood from the remaining two patients yielded Acinetobacter lwoffii. Most patients (78%) resided in the general ward, while four patients (22%) were under intensive care. Genotyping by arbitrarily primed polymerase chain reaction analysis and the temporal sequence of isolation were more useful than phenotyping by antimicrobial susceptibility in the determination of the source of bacteremia, and the intravascular catheter was the leading infection source (39% of cases). The possibility of an association of glucose with the pathogenesis of acinetobacter infection was raised.  (+info)

A new rapidly growing mycobacterial species, Mycobacterium murale sp. nov., isolated from the indoor walls of a children's day care centre. (5/26286)

Scotochromogenic mycobacterial isolates from water-damaged parts of indoor building materials of a children's day care centre represented a phenetically and genetically distinct group of strains. A 16S rDNA dendrogram (1243 bp) showed that the closest species to the new strain MA112/96T was Mycobacterium abscessus. Phylogenetic and phenetic analyses (100 characteristics) grouped the new isolates with M. abscessus, Mycobacterium vaccae, Mycobacterium aurum and Mycobacterium austroafricanum. Ribotyping with Pvull restriction distinguished the 5 isolates from the other 12 most closely related species by the major bands at 6.5-7 kb and 13-15 kb. The cell morphology of the new isolates was typical of mycobacteria, electron microscopy revealed a triple-layered cell wall with an irregular electron-dense outer layer. They grew at 10-37 degrees C, with no growth at 45 degrees C in 5 d. The gene encoding the secreted 32 kDa protein, specific to mycobacteria, was detected by PCR. The main whole-cell fatty acids were characterized by high tuberculostearic acid 10Me-C18:0 (17% at 28 degrees C), which increased with increasing growth temperature (22% at 37 degrees C). The other main fatty acids were C18:1 cis9 and C16:0 (21-20% each), followed by, C17:1 cis9 (14%), C16:1 cis10 (8%) and also a high amount of C20 alcohol (9%). alpha-Mycolic acids, keto-mycolates and wax esters were present (C60-C90), MK-9(H2) (90%) and MK-8(H2) were the main menaquinones. The cellular phospholipids were phosphatidylethanolamine, phosphatidylinositol, phosphatidyl inositolmannosides and diphosphatidylglycerol. Polyamine content was low. G+C content was 72.9 mol%. The new isolates are proposed as a new species, Mycobacterium murale sp. nov. The type strain is MA112/96T (= DSM 44340T).  (+info)

Emergence of multidrug-resistant Salmonella enterica serotype Typhimurium phage-type DT104 among salmonellae causing enteritis in Israel. (6/26286)

The relative frequency of salmonella strains isolated from hospitalized and non-hospitalized patients in Southern Israel changed during the period, 1994-6. Salmonella enterica serotype Typhimurium definitive phage-type 104 (DT104) appeared in Israel in 1994 and became the most prevalent strain in 1996. An outbreak of enteritis due to Salmonella enterica serotype Agona occurred in Israel, in October 1994 and lasted for 4 months. The relative frequency of Salmonella enterica serotype Enteritidis remained almost constant during these years, with seasonal fluctuations only. The importance of the increase in the prevalence of Typhimurium DT104 has been the epidemic spread of a multiresistant strain of R-type ACT (A, ampicillin; C, chloramphenicol; T, tetracycline) belonging to this phage-type. Since 1995 the frequency of Typhimurium DT104 isolates that possess, in addition to the above R-type, a chromosomally encoded resistance to the quinolone drug, nalidixic acid, increased tenfold. In 1996, 27% of the Typhimurium DT104 isolates were of R-type ACTN. S. Enteritidis exhibited over 95% susceptibility to at least eight of the most commonly used antibiotic drugs, and none of the isolates was resistant to quinolone or fluoroquinoline.  (+info)

Apicularens A and B, new cytostatic macrolides from Chondromyces species (myxobacteria): production, physico-chemical and biological properties. (7/26286)

A novel macrolide, apicularen A, was produced by several species of the genus Chondromyces. Initially it was discovered by bioassay-guided RP-HPLC-fractionation of culture extracts of Chondromyces robustus, strain Cm a13. Apicularen A showed no antimicrobial activity, but was highly cytotoxic for cultivated human and animal cells, with IC50 values ranging between 0.1 and 3 ng/ml. A cometabolite of apicularen A, the N-acetylglucosamine glycoside apicularen B, was distinctly less cytotoxic with IC50 values between 0.2 and 1.2 microg/ml, and showed weak activity against a few Gram-positive bacteria. Apicularen A is chemically closely related to the salicylihalamides A and B from the marine sponge Haliclona sp.  (+info)

BE-31405, a new antifungal antibiotic produced by Penicillium minioluteum. I. Description of producing organism, fermentation, isolation, physico-chemical and biological properties. (8/26286)

A new antifungal antibiotic, BE-31405, was isolated from the culture broth of a fungal strain, Penicillium minioluteum F31405. BE-31405 was isolated by adsorption on high porous polymer resin (Diaion HP-20), followed by solvent extraction, precipitation and crystallization. BE-31405 showed potent growth inhibitory activity against pathogenic fungal strains such as Candida albicans, Candida glabrata and Cryptococcus neoformans, but did not show cytotoxic activity against mammalian cells such as P388 mouse leukemia. The mechanism studies indicated that BE-31405 inhibited the protein synthesis of C. albicans but not of mammalian cells.  (+info)

Evaluation of a new Rapid Antimicrobial Susceptibility system for Gram-negative and Gram-positive bloodstream infections: speed...Evaluation of a new Rapid Antimicrobial Susceptibility system for Gram-negative and Gram-positive bloodstream infections: speed...
Blood stream infections (BSIs) are a major cause of morbidity and mortality. The time from taking blood cultures to obtain results of antibiotic sensitivity can be up to five days which impacts patient care. The Alfred 60 AST™ can reduce laboratory time from positive culture bottle to susceptibility results from 16 to 25 h to 5-6 h, transforming patient care. To evaluate the diagnostic accuracy of a rapid antimicrobial susceptibility system, the Alfred 60 AST™, in clinical isolates from patients with BSIs and confirm time to results. 301 Gram-negative and 86 Gram-positive isolates were analysed directly from positive blood culture bottles following Gram staining. Antimicrobial susceptibility results and time-to-results obtained by rapid Alfred 60 AST system and BD Phoenix were compared . A total of 2196 antimicrobial susceptibility test results (AST) were performed: 1863 Gram-negative and 333 Gram-positive. AST categorical agreement (CA) for Alfred 60 AST™ was 95% (1772/1863) for Gram-negative and
https://bmcmicrobiol.biomedcentral.com/articles/10.1186/s12866-019-1654-9
Evaluation of wild-type MIC distributions as a tool for determination of clinical breakpoints for Mycobacterium tuberculosisEvaluation of wild-type MIC distributions as a tool for determination of clinical breakpoints for Mycobacterium tuberculosis
article{5cf566a8-21ef-4c37-927c-b4548bf4fe7f, abstract = {Objectives: The aim of this study was to establish wild-type MIC distributions of first-line drugs for Mycobacterium tuberculosis, as well as to explore the usefulness of such distributions when setting clinical breakpoints. Methods: We determined the MICs of rifampicin, isonlazid and ethambutol for M. tuberculosis using a Middlebrook 7H10 dilution method for 90 consecutive clinical isolates, 8 resistant strains and 16 isolates from the WHO proficiency test panel. M. tuberculosis H37Rv was used for quality control and susceptibility results using 7H10 were compared with the results obtained with BACTEC460. Results: The agreement with BACTEC460 was very high for isonlazid (99.1%) and rifampicin (99.1%) but lower for ethambutol (94.7%). Intra- and inter-assay variation was below one MIC dilution. The MIC distributions for isoniazid and rifampicin provided a clear separation between susceptible and resistant strains. Regarding ethambutol, ...
https://lup.lub.lu.se/search/publication/1507321
Evaluation of CLSI Agar Dilution Method and Trek Sensititre Broth Microdilution Panel for Determining Antimicrobial...Evaluation of CLSI Agar Dilution Method and Trek Sensititre Broth Microdilution Panel for Determining Antimicrobial...
Both the CLSI agar dilution method and Trek Sensititre broth microdilution panel for Streptococcus pneumoniae antimicrobial susceptibility testing were evaluated against the reference CLSI broth microdilution method using the most recently published CLSI breakpoints. While agar dilution was not an optimal method, the commercial panel appeared to be an acceptable method, with minor errors encountered for ceftriaxone, penicillin, and meropenem. ...
https://jcm.asm.org/content/49/2/704.abstract
AID 447039 - Antibacterial activity against Escherichia coli ATCC 11230 after 24 hrs by agar disk diffusion assay - PubChemAID 447039 - Antibacterial activity against Escherichia coli ATCC 11230 after 24 hrs by agar disk diffusion assay - PubChem
BioAssay record AID 447039 submitted by ChEMBL: Antibacterial activity against Escherichia coli ATCC 11230 after 24 hrs by agar disk diffusion assay.
https://pubchem.ncbi.nlm.nih.gov/bioassay/447039
Antibiotics | Free Full-Text | Impact of Reappraisal of Fluoroquinolone Minimum Inhibitory Concentration Susceptibility...
The Clinical Laboratory Standards Institute lowered the fluoroquinolone minimum inhibitory concentration (MIC) susceptibility breakpoints for Enterobacteriaceae and glucose non-fermenting Gram-negative bacilli in January 2019. This retrospective cohort study describes the impact of this reappraisal on ciprofloxacin susceptibility overall and in patients with risk factors for antimicrobial resistance. Gram-negative bloodstream isolates collected from hospitalized adults at Prisma Health-Midlands hospitals in South Carolina, USA, from January 2010 to December 2014 were included. Matched pairs mean difference (MD) with 95% confidence intervals (CI) were calculated to examine the change in ciprofloxacin susceptibility after MIC breakpoint reappraisal. Susceptibility of Enterobacteriaceae to ciprofloxacin declined by 5.2% (95% CI: −6.6, −3.8; p < 0.001) after reappraisal. The largest impact was demonstrated among Pseudomonas aeruginosa bloodstream isolates (MD −7.8, 95% CI: −14.6,
https://0-www-mdpi-com.brum.beds.ac.uk/2079-6382/9/4/189
AID 572901 - Antibacterial activity against blaVIM-2-positive Pseudomonas aeruginosa by CLSI broth microdilution method -...AID 572901 - Antibacterial activity against blaVIM-2-positive Pseudomonas aeruginosa by CLSI broth microdilution method -...
BioAssay record AID 572901 submitted by ChEMBL: Antibacterial activity against blaVIM-2-positive Pseudomonas aeruginosa by CLSI broth microdilution method.
https://pubchem.ncbi.nlm.nih.gov/bioassay/572901
Evaluation of the e test system versus a microtitre broth method for antifungal susceptibility testing of yeasts against...Evaluation of the e test system versus a microtitre broth method for antifungal susceptibility testing of yeasts against...
TY - JOUR. T1 - Evaluation of the e test system versus a microtitre broth method for antifungal susceptibility testing of yeasts against fluconazole and itraconazole. AU - Colombo, Arnaldo L.. AU - Barchiesi, Francesco. AU - Mcgough, Deanna A.. AU - Fothergill, Annette W.. AU - Rinaldi, Michael G.. PY - 1995/7/1. Y1 - 1995/7/1. N2 - The E test strip (AB Biodisk, Solna, Sweden) as an antimicrobial susceptibility testing method is a new and promising tool with broad application in microbiology. This method is less labour intensive than broth dilution methods and may be useful for testing individual clinical isolates.In contrast to several publications comparing E test antibacterial strips with NCCLS reference methods, there is littleinformation about the performance of E test antifungal strips. This study compared fluconazole and itraconazole MICs obtained by E test with a microbroth dilution method performed to NCCLS guidelines.Fluconazole and itraconazole E test results exhibited good ...
https://scholars.uthscsa.edu/en/publications/evaluation-of-the-e-test-system-versus-a-microtitre-broth-method-
Enterobacteriaceae Sepsis Outcome Programme annual report, 2013Enterobacteriaceae Sepsis Outcome Programme annual report, 2013
The Australian Group on Antimicrobial Resistance performs regular period-prevalence studies to monitor changes in antimicrobial resistance in selected enteric Gram-negative pathogens. The 2013 survey focussed for the first time on blood stream infections. Four thousand nine hundred and fifty-eight Enterobacteriaceae species were tested using commercial automated methods (Vitek® 2, BioMérieux; Phoenix™, BD). The results were analysed using Clinical and Laboratory Standards Institute (CLSI) and European Committee on Antimicrobial Susceptibility Testing (EUCAST) breakpoints (January 2014). Of the key resistances, non-susceptibility to the third-generation cephalosporin, ceftriaxone, was found in 7.5%/7.5% (CLSI/EUCAST criteria respectively) of Escherichia coli; 6.3%/6.3% of Klebsiella pneumoniae, and 7.4%/7.4% of K. oxytoca. Non-susceptibility rates to ciprofloxacin were 10.3%/11.3% for E. coli, 4.6%/7.5% for K. pneumoniae, 0.6%/0.6% for K. oxytoca, and 3.6%/6.1% in Enterobacter cloacae. ...
https://espace.curtin.edu.au/handle/20.500.11937/41357
Mueller Hinton Agar with Lysed Horse BloodMueller Hinton Agar with Lysed Horse Blood
Mueller and Hinton developed Mueller Hinton Agar in 1941 to be a protein free medium for isolating pathogenic strains of Neisseria . (3) It was found that Mueller Hinton Agar was useful in identifying sulfonimide-resistant and responsive strains of gonococci. (3) Additionally, in recent times this media has been used in standardized antimicrobial disk susceptibility testing, as described by Bauer, Kirby, et al. (1) Barry and Fay investigated the effects of altering the depth of plated Mueller Hinton Agar on disk diffusion testing, and determined a standardized depth of approximately four millimeters to be sufficient. (2) In 1970 Dewees, et al., studied the effect of storage on Mueller Hinton Agar plates used for antimicrobial disk diffusion zone sizes. Their findings indicated commercially manufactured Mueller Hinton Agar plates were suitable for use in routine susceptibility testing. (6) Mueller Hinton Agar with Lysed Horse Blood is a modification to the traditional Mueller Hinton Agar ...
https://catalog.hardydiagnostics.com/cp_prod/Content/hugo/MuellerHintonAgarLysedHorseBlood.html
A Reference Broth Microdilution Method for Dalbavancin In Vitro Susceptibility Testing of Bacteria that Grow Aerobically |...A Reference Broth Microdilution Method for Dalbavancin In Vitro Susceptibility Testing of Bacteria that Grow Aerobically |...
Here, we present a protocol for determination of dalbavancin susceptibility of clinically relevant Gram-positive bacteria using a broth ...
https://www.jove.com/v/53028/a-reference-broth-microdilution-method-for-dalbavancin-vitro
Euro Clinical Microbiology2019: What have we learned from in vitro antimicrobial susceptibility/resistance and time kill...Euro Clinical Microbiology2019: What have we learned from in vitro antimicrobial susceptibility/resistance and time kill...
Minimum inhibitory concentration (MIC) and mutant prevention concentration (MPC) assays determine either the minimum amount of antimicrobial dru..
https://www.alliedacademies.org/abstract/euro-clinical-microbiology2019-what-have-we-learned-from-in-vitro-antimicrobial-susceptibilityresistance-and-time-kill-measurement-12302.html
Evaluation of Petrifilm™ Select E. coli Count Plate medium to discriminate antimicrobial resistant Escherichia coli |...Evaluation of Petrifilm™ Select E. coli Count Plate medium to discriminate antimicrobial resistant Escherichia coli |...
Screening and enumeration of antimicrobial resistant Escherichia coli directly from samples is needed to identify emerging resistant clones and obtain quantitative data for risk assessment. Aim of this study was to evaluate the performance of 3M™ Petrifilm™ Select E. coli Count Plate (SEC plate) supplemented with antimicrobials to discriminate antimicrobial-resistant and non-resistant E. coli. A range of E. coli isolates were tested by agar dilution method comparing the Minimal Inhibitory Concentration (MIC) for eight antimicrobials obtained by Mueller-Hinton II agar, MacConkey agar and SEC plates. Kappa statistics was used to assess the levels of agreement when classifying strains as resistant, intermediate or susceptible. SEC plate showed that 74% of all strains agreed within ± 1 log2 dilution when comparing MICs with Mueller-Hinton II media. High agreement levels were found for gentamicin, ampicillin, chloramphenicol and cefotaxime, resulting in a kappa value of 0.9 and 100% agreement within ±
https://rd.springer.com/article/10.1186/1751-0147-50-38?error=cookies_not_supported&code=df05fe90-490a-4715-990f-e62db56ed707
Effects of systemic administration of sitafloxacin on subgingival microflora and antimicrobial susceptibility profile in acute...
TY - JOUR. T1 - Effects of systemic administration of sitafloxacin on subgingival microflora and antimicrobial susceptibility profile in acute periodontal lesions. AU - Tomita, Sachiyo. AU - Kasai, Shunsuke. AU - Ihara, Yuichiro. AU - Imamura, Kentaro. AU - Kita, Daichi. AU - Ota, Koki. AU - Kinumatsu, Takashi. AU - Nakagawa, Taneaki. AU - Saito, Atsushi. PY - 2014/6. Y1 - 2014/6. N2 - The aim of this study was to assess the effect(s) of systemic administration of sitafloxacin on subgingival microbial profiles of acute periodontal lesions. Antimicrobial susceptibility of clinical isolates was also investigated. Patients with acute phases of chronic periodontitis were subjected to clinical examination and microbiological assessment of their subgingival plaque samples by culture technique. Sitafloxacin was then administered (100mg/day for 5 days) systemically. The clinical and microbiological examinations were repeated 6-8 days after administration. Susceptibilities of clinical isolates to various ...
https://keio.pure.elsevier.com/ja/publications/effects-of-systemic-administration-of-sitafloxacin-on-subgingival
Biofilm production and antibiotic susceptibility profile of Escherichia coli isolates from HIV and AIDS patients in the...Biofilm production and antibiotic susceptibility profile of Escherichia coli isolates from HIV and AIDS patients in the...
Biofilm production and antibiotic susceptibility profile of Escherichia coli isolates from HIV and AIDS patients in the Limpopo Province
https://www.ajol.info/index.php/ajb/article/view/127605
Multicenter laboratory evaluation of the bioMérieux Vitek antimicrobial susceptibility testing system with 11 antimicrobial...
A four-center study in which a total of 1,082 recent clinical isolates of members of the family Enterobacteriaceae and Pseudomonas aeruginosa were examined versus 11 antimicrobial agents with the bioMérieux Vitek susceptibility test system (Hazelwood, Mo.) and the GNS-F6 card was conducted. In addition, a challenge set consisting of the same 200 organisms was examined in each of the four participating laboratories. Results obtained with the Vitek system were compared to MICs determined by a standardized broth microdilution method. For purposes of comparison, susceptibility categories (susceptible, intermediate, or resistant) were assigned on the basis of the results of both methods. The result of the broth microdilution test was considered definitive. The total category error rate with the Vitek system and the recent clinical isolates (11,902 organism-antimicrobial comparisons) was 4.5%, i.e., 1.7% very major errors, 0.9% major errors, and 1.9% minor errors. The total category error rate calculated
https://www.ndm.ox.ac.uk/publications/384056
Studies on the postantibiotic effect and the postantibiotic sub-MIC effect of meropenem. - PubMed - NCBIStudies on the postantibiotic effect and the postantibiotic sub-MIC effect of meropenem. - PubMed - NCBI
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
https://www.ncbi.nlm.nih.gov/pubmed/8360126?dopt=Abstract
The Kirb-Bauer Disk Diffusion TechniqueThe Kirb-Bauer Disk Diffusion Technique
The Kirb-Bauer Disk Diffusion Technique was performed on 2 different Mueller-Hinton Agar plates. One plate had Escherichia Coli spread on it and the other plate has Staphylococcus Epidermidis spread on it. Both plates had.
https://brainmass.com/biology/pharmacology-and-toxicology/kirb-bauer-disk-diffusion-technique-509553
Evaluation of usefulness and PK-PD analysis of meropenem in children with various infections<...
TY - JOUR. T1 - Evaluation of usefulness and PK-PD analysis of meropenem in children with various infections. AU - Sato, Yoshitake. AU - Sandoh, Mitsuru. AU - Hanaki, Hideaki. AU - Suzuki, Yumiko. AU - Yoshida, Mikinobu. AU - Kizu, Junko. PY - 2012/5. Y1 - 2012/5. N2 - We conducted a study of meropenem(MEPM) in a total of 29 children with various infections (moderate to severe pneumonia in 25, upper respiratory infection in 3, and urinary tract infection in 1) to demonstrate the efficacy and safety and assess the relationship between the time above the minimal inhibitory concentration (MIC) (T , MIC), calculated based on the pharmacokinetic simulation analysis using blood concentration data from subjects, and the clinical response. In accordance with the package insert in Japan, MEPM was administered at a dose of 20 mg/kg three times daily, the highest dose in the usual dosage range. Each dose was administered by infusion over 30 minutes. The minimum inhibitory concentration (MIC) values of MEPM ...
https://keio.pure.elsevier.com/en/publications/evaluation-of-usefulness-and-pk-pd-analysis-of-meropenem-in-child
Biopolymers and CellBiopolymers and Cell
Aim. The screening of antimicrobial and cytotoxic activities of thiazolo[4,5-b]pyridine derivatives was accomplished. Methods. The antibacterial and antifungal activities of synthesized thiazolopyridines were evaluated in vitro with the agar diffusion and broth microdilution methods using clinical and reference strains of Gram-positive, Gram-negative bacteria and yeasts. The structure-antibacterial/antifungal activity relationships of the screened compounds were established. The target compounds were screened for their cytotoxicity effects on HaCaT and HEK293 cells using MTT assay. Results. The highest antimicrobial activity was observed for compound V 2-oxo-7-thiophen-2-yl-2,3-dihydrothiazolo[4,5-b]pyridine-5-carboxylic acid with minimal inhibitory concentration (MIC) 12.5 μg/mL against Candida albicans. At the same time, the synthesized compounds were explored in the interaction with amoxicillin against multidrug resistant clinical isolates of ESβL+ Klebsiella pneumonie and Staphylococcus ...
http://biopolymers.org.ua/content/37/2/153/
AAOHN : Blogs : Clinician Outreach and Communication Activity (CDC): HAN 401-CDC Recommendations for Diagnosing and Managing...AAOHN : Blogs : Clinician Outreach and Communication Activity (CDC): HAN 401-CDC Recommendations for Diagnosing and Managing...
Summary. This Health Advisory describes the identification of emerging Shigella strains with elevated minimum inhibitory concentration values for ciprofloxacin and outlines new recommendations for clinical diagnosis, management, and reporting, as well as new recommendations for laboratories and public health officials. Current interpretive criteria provided by the Clinical and Laboratory Standards Institute (CLSI) categorize these strains as susceptible to ciprofloxacin, which is a fluoroquinolone antibiotic and a key agent in the management of Shigella infections.. However, recent data from the Centers for Disease Control and Prevention (CDC) and state and local public health partners show that these strains often have a quinolone resistance gene that may lead to clinically significant reduced susceptibility to fluoroquinolone antibiotics. Clinicians treating patients with multidrug-resistant shigellosis for whom antibiotic treatment is indicated should avoid prescribing fluoroquinolones if the ...
http://aaohn.org/blog/clinician-outreach-and-communication-activity-
microbiology Protocols and Video...microbiology Protocols and Video...
Video articles in JoVE about microbiology include Unraveling the Unseen Players in the Ocean - A Field Guide to Water Chemistry and Marine Microbiology, The WinCF Model - An Inexpensive and Tractable Microcosm of a Mucus Plugged Bronchiole to Study the Microbiology of Lung Infections, Aseptic Laboratory Techniques: Plating Methods, Whole Genome Sequencing of Candida Glabrata for Detection of Markers of Antifungal Drug Resistance, Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction, Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS, Subtyping of Campylobacter jejuni ssp. doylei Isolates Using Mass Spectrometry-based PhyloProteomics (MSPP), A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii, A Reference Broth Microdilution Method for Dalbavancin In Vitro Susceptibility Testing of
https://www.jove.com/keyword/microbiology
Ceftolozane/tazobactam susceptibility testing in extended-spectrum betalactamase- and carbapenemase-producing gram-negative...Ceftolozane/tazobactam susceptibility testing in extended-spectrum betalactamase- and carbapenemase-producing gram-negative...
In the last 10 to 20 years, we have witnessed a dramatic increase in the proportion of bacterial pathogens resistant to multiple antimicrobial agents. Indeed, the driving force behind the increasing rates of resistance is ultimately the abuse and misuse of antimicrobial agents, whether inadequately administered to patients and livestock or unintentionally released into the environment. This issue is very important regarding the resistance towards quinolones, carbapenems, and third-generation cephalosporins. The latter relates to the increased prevalence of extended-spectrum β-lactamases among Enterobacterales. Surveillance studies of antimicrobial resistance and antibiotic consumption have drawn attention to this phenomenon and should be used to drive political campaigns to contain resistance [18, 19]. Ceftolozane/tazobactam (C/T) has been approved few years ago and represents a therapy option in particular infections associated with Gram-negative bacteria, including ESBL-producing isolates. ...
https://akjournals.com/view/journals/1886/9/1/article-p1.xml?rskey=PBIYob&result=71
Papers with the keyword ampC betalactamase | Read by QxMDPapers with the keyword ampC betalactamase | Read by QxMD
PURPOSE: Extended spectrum β-lactamase (ESBL) and AmpC β-lactamase are important mechanisms of betalactam resistance among Enterobacteriaceae . The ESBL confirmation test described by Clinical Laboratory Standards Institute (CLSI) is in routine use. This method fails to detect ESBL in the presence of AmpC. Therefore, we compared two different ESBL detection methods against the CLSI confirmatory test. MATERIALS AND METHODS: A total 200 consecutive clinical isolates of Enterobacteriaceae from various clinical samples were tested for ESBL production using (i) CLSI described phenotypic confirmatory test (PCT), (ii) boronic acid disk potentiation test and (iii) cefepime-CA disk potentiation method ...
https://www.readbyqxmd.com/keyword/110318
and : Susceptibility Testing of 120 Isolates to Six Antimicrobial Agents Using Disk Diffusion (EUCAST), Etest, and Broth...and : Susceptibility Testing of 120 Isolates to Six Antimicrobial Agents Using Disk Diffusion (EUCAST), Etest, and Broth...
and : Susceptibility Testing of 120 Isolates to Six Antimicrobial Agents Using Disk Diffusion (EUCAST), Etest, and Broth Microdilution Techniques
https://openmicrobiologyjournal.com/VOLUME/11/PAGE/160/FULLTEXT/
Bristol AMR funded projects | Antimicrobial Resistance | University of BristolBristol AMR funded projects | Antimicrobial Resistance | University of Bristol
This project builds on an initial pump-priming project funded by EPSRC BristolBridge and subsequent funding (via the EBI, the Longitude Prize and many others) to develop a rapid antimicrobial susceptibility test to inform antibiotic prescribing. This new work will scope the parameters for the constraints for end-users, particularly GPs and other community health workers working in primary care and urgent care. A Knowledge Mobilisation approach will be taken to co-produce a stakeholder informed plan to outline the challenges of designing, prototyping and economically evaluating a novel SCFI antimicrobial resistance device to help combat AMR in community healthcare settings. The projects industry partner is Vitamica Ltd - a University of Bristol spin out company formed after the development of the SCFI technology. ...
https://www.bristol.ac.uk/amr/bristol-amr-funded-projects-/
Characterization of antimicrobial resistance of Pseudomonas aeruginosa isolated from canine infections - Lin - 2012 - Journal...Characterization of antimicrobial resistance of Pseudomonas aeruginosa isolated from canine infections - Lin - 2012 - Journal...
Clinical and Laboratory Standards Institute (2008) Performance standards for antimicrobial disk and dilution susceptibility test for bacteria isolated from animals; approved standard, 3rd edn. In CLSI Document M31-A3. ed. Watts, J.L., Shryock, T.R., Apley, M., Bade, D.J., Brown, S.D., Gray, J.T., Heine, H., Hunter, R.P. et al. , pp. 32-35. Wayne, PA: Clinical and Laboratory Standards Institute ...
http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2672.2012.05304.x/references
Isolation and characterization of metal and antibiotic resistant psychrotrophic bacteria from refrigerated spoiled food -...Isolation and characterization of metal and antibiotic resistant psychrotrophic bacteria from refrigerated spoiled food -...
The aim of this study was to isolate and characterize psychrotrophic bacteria resistant to antibiotic and metals from cold samples of refrigerated spoiled food and ice. Two isolates named H and F were successfully isolated from samples incubated at 10°C and 4°C, respectively. Both isolates were able to grow at 4°C, 10°C, 20°C and 30°C and exhibited multidrug resistance to antibiotics (chloramphenicol, ampicillin, tetracycline and kanamycin). Bacteria H and F were then further tested for their resistance to metal ions such as Cd2+, Zn2+, Cr 6+ and As 3+ at concentrations ranging from 0-10 mM. The results of the test revealed that the minimum inhibitory concentration (MIC) for isolate H was determined at 2 mM for all the metal ions. By comparison, isolate F was highly resistant to Cr6+, Cd2+ and Zn2+ with MIC of 10 mM for these cations, while MIC for As3+ was 4 mM. The results of comparing 16S rRNA gens demonstrated that isolate F has 98% identity match with Bacillus sp. This strain could be ...
http://eprints.utm.my/id/eprint/53275/
Antibiotic Resistance Among Ocular Pathogens - Results from the ARMOR Surveillance Study 2013-Present | IOVS | ARVO JournalsAntibiotic Resistance Among Ocular Pathogens - Results from the ARMOR Surveillance Study 2013-Present | IOVS | ARVO Journals
Purpose: The Antibiotic Resistance Monitoring in Ocular micRoorganisms (ARMOR) study was initiated in 2009 to survey resistance levels among ocular pathogens on a nationwide scale. Here we report the complete study results for 2013 compared to preliminary 2014 data.. Methods: Isolates of Streptococcus pneumoniae, Staphylococcus aureus, coagulase-negative staphylococci (CoNS), Pseudomonas aeruginosa, and Haemophilus influenzae were subjected to antibiotic susceptibility testing. In 2013, 543 isolates were collected from 22 sites; 140 isolates have been collected from 7 sites to date in 2014. Minimum inhibitory concentrations were determined by broth microdilution for up to 16 representative antibiotics per CLSI methods. Systemic breakpoints (where available) were used to categorize isolates as susceptible or non-susceptible (intermediate and resistant).. Results: With the exception of a fluoroquinolone-resistant isolate and an azithromycin-resistant isolate observed in 2014, all H. influenzae ...
http://iovs.arvojournals.org/article.aspx?articleid=2332649
CLSI Blog: Clinical & Laboratory Standards ArticlesCLSI Blog: Clinical & Laboratory Standards Articles
Read the latest articles on clinical and laboratory standards from the Clinical & Laboratory Standards Institute (CLSI). Find great content from CLSI.
https://clsi.org/about/blog/?page=10
CLSI Blog: Clinical & Laboratory Standards ArticlesCLSI Blog: Clinical & Laboratory Standards Articles
Read the latest articles on clinical and laboratory standards from the Clinical & Laboratory Standards Institute (CLSI). Find great content from CLSI.
https://clsi.org/about/blog/?page=8
Antimicrobial susceptibility testing of dermatophytes--comparison of the agar macrodilution and broth microdilution tests. -...Antimicrobial susceptibility testing of dermatophytes--comparison of the agar macrodilution and broth microdilution tests. -...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
https://www.ncbi.nlm.nih.gov/pubmed/9444406?dopt=Abstract
FASTinovFASTinov
Next Generation PHENOTYPIC SUSCEPTIBILITY TESTING Assays. ​FASTinov is a R&D intensive Startup with a patented disruptive technology to perform fast and reliable antimicrobial susceptibility tests in acute care settings. Context : The global emergence and spread of antimicrobial resistance is a major medical and economic problem . When an infection is diagnosed, the physician is required to start an empiric larg e spectrum therapy, since current comprehensive and proven susceptibility profile methods require, at least, 48h. FASTinov approach : In order to support clinical decisions with a fast turnaround time, FASTinov offers a unique time-saving and comprehensive solution starting directly from positive blood cultures. FASTinov innovative approach allows for the determination of the susceptibility phenotype in 2 hours, compared with +48 hours needed for current standard methods. Disruptive Technology : FAST patented methodology (Flow Cytometry Antimicrobial Susceptibility Test) fills a gap ...
http://fastinov.com
Bacteriological Profiles and Antibiotic Susceptibility Patterns in Complicated Bacterial Infections of the Ears, Nose and ThroatBacteriological Profiles and Antibiotic Susceptibility Patterns in Complicated Bacterial Infections of the Ears, Nose and Throat
Florin Anghelina, Ovidiu Zlatian, Mircea Sorin Ciolofan, Daniela Calina, Anca Oana Docea, Razvan Hainarosie, Octavian Dragos Palade, Liliana Anghelina, Cristian Dragos Stefanescu, Laura Mazilu, Andra Iulia Suceveanu, Catalina Pietrosanu, Andrei Osman - Bacteriological Profiles and Antibiotic Susceptibility Patterns in Complicated Bacterial Infections of the Ears, Nose and Throat
https://revistadechimie.ro/Articles.asp?ID=7770
Ashlynn VanatterAshlynn Vanatter
Antibiotic resistance is the ability of bacteria to survive exposure to antibiotics that were designed to kill them or inhibit their growth This experiment aimed to answer the question if chronic low-grade usage of amoxicillin, ciprofloxacin, or trimethoprim promoted antibiotic-resistant Escherichia coli over time. This in vitro study tested if the concentration of antibiotics and the type of antibiotic affected the minimum inhibitory concentration (MIC) required for each antibiotic to inhibit bacterial growth. To find these measurements a MIC assay was used, and the bacterial concentrations in each well were recorded and compared. The expectation of this study was that as the bacteria were treated with high concentration antibiotics for a longer amount of time, a lower bacterial growth would be observed. A 2-Factor ANOVA reported that in a full factorial model, there was not a significant interaction between antibiotic exposure and type of bacterial concentration (F= 1.597, df=2,12, p= 0.2428), ...
https://researchsymposium.mssu.edu/ashlynn-vanatter/
Search by cephalosporin | The Antimicrobial Index Knowledgebase - TOKU-ESearch by cephalosporin | The Antimicrobial Index Knowledgebase - TOKU-E
The Antimicrobial Index is comprised of literature-based minimum inhibitory concentration values collected from hundreds of scientific papers as well as other relevant antimicrobial potency data.
http://antibiotics.toku-e.com/m/?w=cephalosporin
Spatiotemporal microbial evolution on antibiotic landscapes | ScienceSpatiotemporal microbial evolution on antibiotic landscapes | Science
Challenging bacteria in spatial gradients of antibiotics leads to large increases in resistance through sequential adaptive steps across competing lineages (Fig. 1 and movie S1). We first set up the MEGA-plate with symmetric four-step gradients of trimethoprim (TMP) or ciprofloxacin (CPR) proceeding inward with order-of-magnitude increases in concentration per step [Fig. 1A; TMP: 0, 3, 30, 300, and 3000 × wild-type minimum inhibitory concentration (MIC); CPR: 0, 20, 200, 2000, and 20,000 × MIC] and inoculated the drug-free regions with Escherichia coli. Bacteria swim and spread until they reach a concentration in which they can no longer grow (TMP, Fig. 1C and movies S1 and S2; CPR, movie S3). As resistant mutants arise in the population, their descendants migrate into the next step of drug concentration and fan out (Fig. 1C, 88 hours). Adjacent mutant lineages exclude each other and compete for limited space, resulting in some lineages entirely blocking off growth of others (Fig. 1C). When ...
https://science.sciencemag.org/content/353/6304/1147
Product References - Tagged Animal Whole Blood - Innovative ResearchProduct References - Tagged Animal Whole Blood - Innovative Research
Innovative Grade US Origin Horse Whole Blood Lysed from Innovative Research was used in the following study: Mathematical modeling of the inoculum effect: six applicable models and the MIC advancement point concept Jessica R. Salas, Majid Jaberi-Douraki, Xuesong Wen, Victoriya V. Volkova FEMS Microbiology Letters 21 January 2020 …Antimicrobial treatment regimens against bacterial pathogens are designed using the drugs minimum inhibitory concentration (MIC) measured at the bacterial density of 5.7 log10(colonyforming units (CFU)/mL) in vitro. However, MIC changes with pathogen density, which varies among infectious diseases and during treatment. Incorporating this into treatment design requires realistic mathematical models of.... ...
https://www.innov-research.com/blogs/product-references/tagged/animal-whole-blood
IntermediateIntermediate
Scattergram #2 -- Correlation of TMP/SMX MIC and zone diameters for S. pneumoniae. Horizontal and vertical lines represent MIC and zone diameter breakpoints. In this case, the isolates form a continuum, with the breakpoint for resistant and susceptible not being obvious. In this case one can not predict how the isolates which fall into the intermediate zone will behave in vivo. The breakpoints are set to maximize the predictive value of the test while minimizing errors (ie. it is preferable to call an isolate intermediate, than to incorrectly call it sensitive or resistant ...
http://www.uphs.upenn.edu/bugdrug/antibiotic_manual/int.html
Microbiology Society Journals | ARIBA: rapid antimicrobial resistance genotyping directly from sequencing readsMicrobiology Society Journals | ARIBA: rapid antimicrobial resistance genotyping directly from sequencing reads
Antimicrobial resistance (AMR) is one of the major threats to human and animal health worldwide, yet few high-throughput tools exist to analyse and predict the resistance of a bacterial isolate from sequencing data. Here we present a new tool, ARIBA, that identifies AMR-associated genes and single nucleotide polymorphisms directly from short reads, and generates detailed and customizable output. The accuracy and advantages of ARIBA over other tools are demonstrated on three datasets from Gram-positive and Gram-negative bacteria, with ARIBA outperforming existing methods.
http://mgen.microbiologyresearch.org/content/journal/mgen/10.1099/mgen.0.000131
Jundishapur Journal of Microbiology - 10, 3Jundishapur Journal of Microbiology - 10, 3
Ashraf Mohamadkhani, Sima Besharat, Golnosh Gol-Jah Rad, Akbar Pour Dadash Asiabar, Gholamreza Roshandel, Akram Pourshams, Hossein Poustchi ...
http://jjmicrobiol.com/en/issue/1529.html
Antibiotic resistance profiling | Applied MathsAntibiotic resistance profiling | Applied Maths
The Antibiotics susceptibility plugin in BIONUMERICS automatically converts inhibition zone diameters and MIC values into SIR categories for antibiotic resistance typing.
https://www.applied-maths.com/applications/antibiotic-resistance-profiling
Indian Patents. 249237:PROCESS FOR THE PREPARATION OF THIAZOLO PYRIMIDINES OF FORMULA I
Appropriate medium(a blood agar plate)and incubated overnight at 35C Inoculate a tube that contains 2 ml of saline or Mueller-hinton broth With five or more colonies from the agar plate and adjust turbidity to Match a McFarland standard(approximately 10 CFU/ml) Transfer 0.1 ml of the turbid broth into 10 ml of Mueller-Hinton Broth,inoculate in shaking water bath or equivalent at 35C until Turbid(5 to 6 hours for rapid growth).The relevant control organism Should be inoculated into 3 ml of broth and incubated without shaking Until turbid.This represents a midexponential phase of growth. Prepare twofold serial dilutions of the antibiotic in 2 ml of Mueller-Hinton broth.Use acid washed borosilicated glass tubes. Standardise the inoculum of the patients organism and the ...
http://www.allindianpatents.com/patents/249237-process-for-the-preparation-of-thiazolo-pyrimidines-of-formula-i
McFarland Tutoring: Tutors in McFarland, WIMcFarland Tutoring: Tutors in McFarland, WI
Rating: 4.8/5. Many top tutors available in McFarland, WI and surrounding suburbs for award-winning private in-home or online tutoring.
https://www.varsitytutors.com/tutoring-mcfarland-wi
rapidmicrobiology » First Automated Phenotypic Test for Carbapenemase Producing Organismsrapidmicrobiology » First Automated Phenotypic Test for Carbapenemase Producing Organisms
Fully integrated within BD Phoenix panels, the new BD Phoenix CPO detect test enables laboratories to offer a more comprehensive antimicrobial susceptibility test profile while improving laboratory process efficiency.
http://www.rapidmicrobiology.com/news/first-automated-phenotypic-test-for-carbapenemase-producing-organisms/
such clinical keflex sibo Rosenbaum ALsuch clinical keflex sibo Rosenbaum AL
HayrehSS,PeвerJ,ZimmermanMBMorphologicchangesinchronichigh-pressureexperi- mental glaucoma in rhesus monkeys. Prostate Cancer Trialistsв Collaborative Group. Fig. 4 In Vitro Antimicrobial Susceptibility Testing Therapy keflx active pertussis keflex sibo prophylaxis of close contacts is considered to minimize transmission (6).
http://moizveri.ru/buy-tabs-online-discount-prices/keflex-sibo.html
Studies Confirm Rapid Phenotypic Susceptibility Results Enable Earlier Antimicrobial Intervention and Better Patient Outcomes |...Studies Confirm Rapid Phenotypic Susceptibility Results Enable Earlier Antimicrobial Intervention and Better Patient Outcomes |...
The first of the studies is RAPIDS-GN (ClinicalTrials.gov # NCT03218397), a randomized controlled trial conducted at Mayo Clinic and UCLA. RAPIDS-GN focused on Gram-negative bacteremia and randomized patients to be tested by the BC kit or legacy methods. The study met the primary endpoint of therapy optimization, reporting time to first Gram-negative antibiotic change a full 24 hours sooner than legacy methods (17.4 hours vs. 42.1 hours, p,0.01) and time to any antibiotic change 6 hours sooner (8.6 hours vs. 14.9 hours, p=0.02). ...
https://acceleratediagnostics.com/news/studies-confirm-rapid-phenotypic-susceptibility-results-enable-earlier-antimicrobial-intervention-better-patient-outcomes/
Antimicrobial Susceptibility Testing Market | 2020-2027 | Industry Report | Covid InsightsAntimicrobial Susceptibility Testing Market | 2020-2027 | Industry Report | Covid Insights
The Antimicrobial Susceptibility Testing Market is expected to register a CAGR of over 5.3 % during the forecast period. This report is segmented by Products, by Type, by application and Geography.
https://www.mordorintelligence.com/industry-reports/antimicrobial-susceptibility-testing-market
McFarland Cascade (Stella-Jones) to acquire Lufkin Creosoting - 2016/02/03 - MarketLine Financial Deals
Stella-Jones, Inc., wholly-owned subsidiary McFarland Cascade Holdings, Inc., has signed a non-binding letter of intent to acquire the shares of Lufkin Creosoting Co., Inc.
http://www.alacrastore.com/storecontent/MarketLine-Financial-Deals/McFarland-Cascade-Stella-Jones-to-acquire-Lufkin-Creosoting-2052-117822
Antimicrobial Susceptibility Pattern of Staphylococcus aureus Isolated from Clinical Specimens from Wound SamplesAntimicrobial Susceptibility Pattern of Staphylococcus aureus Isolated from Clinical Specimens from Wound Samples
Staphylococcus aureus (S. aureus) is a major pathogen associated with serious community and hospital-acquired infections. Methicillin resistant S. aureus (MRSA) is now endemic in India. Methicillin-resistant Staphylococcus aureus (MRSA) has recently emerged as a major nosocomial pathogen worldwide with a significant morbidity and mortality. Early detection of emerging trends in antimicrobial resistance may facilitate implementation of effective control measures. The present study thus attempts to characterize the MRSA isolates and explore the antibiotic susceptibility pattern of MRSA isolated from wound samples at a tertiary care hospital, Central India. The present study was conducted to characterize 120 MRSA isolates, isolated from wound samples and their antibiotic susceptibility patterns. MRSA was identified by oxacillin disc diffusion test, cefoxitin disc diffusion test and resistance to oxacillin by the Minimum inhibitory concentration (MIC) method. Study also detected inducible clindamycin
https://www.ijcmas.com/abstractview.php?ID=7057&vol=7-3-2018&SNo=230
Effects of various antimicrobial agents on multi-directional differentiation potential of bone marrow-derived mesenchymal stem...Effects of various antimicrobial agents on multi-directional differentiation potential of bone marrow-derived mesenchymal stem...
Effects of various antimicrobial agents on multi-directional differentiation potential of bone marrow-derived mesenchymal stem cells
https://www.wjgnet.com/1948-0210/coretip/v11/i6/322.htm
Comparison Of Susceptibility Test Methods For Determining Oxacillin Resistance In Clinical Isolates | Asian Journal of...Comparison Of Susceptibility Test Methods For Determining Oxacillin Resistance In Clinical Isolates | Asian Journal of...
Abstract:. To compare conventional phenotypic methods for the detection of methicillin in Staphylococci aureus in routine laboratory practice with reference to an established molecular method. This study was conducted on a selection of 30 isolates of methicillin resistant Staphylococci aureus (MRSA) from clinical specimens. The Kirby- Bauer disc diffusion tests and oxacillin screen ager method were performed on all isolates using the presence of penicillin binding protein (PBP2a) as the reference standard. A commercial latex agglutination test (Oxoid, UK) was assessed for the detection of penicillin binding protein 2a (PBP2a), the Mec A gene product. Twenty of 30 isolates were positive to PBP2a and concomitant manifest resistance to (oxacillin) was confirmed using Kirby-Bauer diffusion test. All the thirty isolates were resistant using disk diffusion method. The specificity and sensitivity of this method, in comparison with PBP2a was 100% in our examined strains, whereas the specificity and ...
http://ajphs.com/article/2011/1/1/26-29
View of DETECTION OF AMINOGLYCOSIDE AND QUINOLONE RESISTANCE GENES AND EVALUATION OF POLYMYXIN B SUSCEPTIBILITY PROFILE IN...View of DETECTION OF AMINOGLYCOSIDE AND QUINOLONE RESISTANCE GENES AND EVALUATION OF POLYMYXIN B SUSCEPTIBILITY PROFILE IN...
Acinetobacter baumannii is an important opportunistic pathogen, responsible for approximately 10% of all gram-negative nosocomial infection. The aim of this study was to determine aminoglycoside and quinolone resistance genes and their antimicrobial susceptibility profile in the clinically A. baumannii. In this cross-sectional study, a total of 100 nonduplicative A. baumannii isolates were collected from different clinical samples. Antimicrobial susceptibility test was performed by disk diffusion method. QnrA, anrB, qnrS, aac(3)-IIa, and aac(6′)-Ib genes were identified using PCR method. The results of antibiotic susceptibility test showed that polymyxin B was the most effective antimicrobial against A. baumannii. 97%, 95% and 82% of isolates were resistant to cefepime, ceftriaxone, and amikacin, respectively. The molecular distribution of aac(3)-IIa, aac(6′)-Ib, and qnrA genes were 45%, 50%, and 50% of isolates, respectively. However, qnrB and qnrS genes could not be detected in any strain. ...
https://www.mjhid.org/index.php/mjhid/article/view/2018.044/html
Antibiotic sensitivity test - definition of antibiotic sensitivity test by The Free DictionaryAntibiotic sensitivity test - definition of antibiotic sensitivity test by The Free Dictionary
Define antibiotic sensitivity test. antibiotic sensitivity test synonyms, antibiotic sensitivity test pronunciation, antibiotic sensitivity test translation, English dictionary definition of antibiotic sensitivity test. n. A substance, such as penicillin or erythromycin, produced by or derived from certain microorganisms, including fungi and bacteria, that can destroy or...
https://www.thefreedictionary.com/antibiotic+sensitivity+test
Invasive Candida guilliermondii infection: In vitro susceptibility studies and molecular analysis<...
TY - JOUR. T1 - Invasive Candida guilliermondii infection. T2 - In vitro susceptibility studies and molecular analysis. AU - Vazquez, J. A.. AU - Lundstrom, T.. AU - Dembry, L.. AU - Chandrasekar, P.. AU - Boikov, D.. AU - Perri, M. B.. AU - Zervos, M. J.. PY - 1995/12/1. Y1 - 1995/12/1. N2 - Candida guilliermondii is rarely isolated from humans. We describe a case of disseminated C. guilliermondii with associated purulent pericarditis, despite high-dose amphotericin B (AmB), in a 19-year-old female with aplastic anemia who underwent BMT. In vitro susceptibility studies of the 13 clinical isolates, two control strains and one environmental isolate revealed a minimum inhibitory concentration (MIC) range of (0.19-1.56 μg/ml) for AmB and (1.25-10 μg/ml) for fluconazole. Pulsed-field gradient gel electrophoresis was performed to evaluate possible similarities between strains. This case is significant for several reasons, the high degree and prolonged duration of fungemia despite high-dose AmB and ...
https://augusta.pure.elsevier.com/en/publications/invasive-candida-guilliermondii-infection-in-vitro-susceptibility
Sub-inhibitory concentrations of vancomycin prevent quinolone-resistance in a penicillin-resistant isolate of Streptococcus...Sub-inhibitory concentrations of vancomycin prevent quinolone-resistance in a penicillin-resistant isolate of Streptococcus...
The continuous spread of penicillin-resistant pneumococci represents a permanent threat in the treatment of pneumococcal infections, especially when strains show additional resistance to quinolones. The main objective of this study was to determine a treatment modality impeding the emergence of quinolone resistance. Exposure of a penicillin-resistant pneumococcus to increasing concentrations of trovafloxacin or ciprofloxacin selected for mutants resistant to these drugs. In the presence of sub-inhibitory concentrations of vancomycin, development of trovafloxacin-resistance and high-level ciprofloxacin-resistance were prevented. Considering the risk of quinolone-resistance in pneumococci, the observation might be of clinical importance.
https://bmcmicrobiol.biomedcentral.com/articles/10.1186/1471-2180-1-9
Antibiotic susceptibility profile of uropathogens isolated from pregnant women in selected hospitals in Ilorin |...Antibiotic susceptibility profile of uropathogens isolated from pregnant women in selected hospitals in Ilorin |...
Background: Urinary tract infection (UTI) is one of the most common infections among pregnant women and if untreated could lead to serious complications.. Objective: This work was carried out to determine the prevalence rate of Enterobacteriaceae uropathogens and their antibiotics susceptibility profile among pregnant women attending two ante-natal clinics in Ilorin, Nigeria.. Materials and Methods: A total of 111 pregnant women between the ages of 18-50 attending ante-natal clinic at University of Ilorin Teaching Hospital and Civil Service Hospital, Ilorin participated in the study. Mid-stream urine samples were collected and cultured on Cysteine-Lactose-Electrolyte Deficient agar. Presence of significant bacteriuria (, 105 cfu/mL) was determined using the plate count method. Antibiotic susceptibility testing was done using Kirby-Bauer disk diffusion technique.. Results: Of the 111 urine samples collected, 27.9% of them were found positive on culture. Among the isolated organisms, Klebsiella ...
https://www.ajol.info/index.php/njpr/article/view/188240
Bacteriology and Antibiotic Susceptibility Profile of Isolates from Suya Samples in Khana Local Government Area, Rivers State,...Bacteriology and Antibiotic Susceptibility Profile of Isolates from Suya Samples in Khana Local Government Area, Rivers State,...
This study centred on the assessment of Suyas ready-to - eat (RTE) bacteriology and antibiotic susceptibility profile. Samples were bought randomly from manufacturing sources and vendors, and a number of putative bacterial pathogens were isolated according to traditional microbiological protocols. Roasted and sold Suya aerobic plate counts (APCs) ranged from 2.4×104-1.39×105 CFUg-1 while total coliform counts (TCCs) ranged from 1.5×104-6.2×104 CFU / g. Ten (10) bacterial species, including six (6) Gram-positive and four (4) Gram-negative bacteria, were described in total. Staphylococcus aureus (20%), Escherichia coli and Micrococcus luteus (16%), respectively, were the most commonly isolated bacteria. Results of the antibiotic susceptibility test showed that Ciprofloxacin and Levofloxacin had the highest inhibition zones ranging from 21-41 mm (among others) for Gram positive and negative bacteria with high sensitivity and broad spectrum levels. Action. Action In comparison, Klebsiella ...
https://journalgazett.com/2020/10/09/bacteriology-and-antibiotic-susceptibility-profile-of-isolates-from-suya-samples-in-khana-local-government-area-rivers-state-nigeria/
In vitro activity of gemifloxacin against recent clinical isolates of bacteria in Korea.<...In vitro activity of gemifloxacin against recent clinical isolates of bacteria in Korea.<...
TY - JOUR. T1 - In vitro activity of gemifloxacin against recent clinical isolates of bacteria in Korea.. AU - Yong, Dong Eun. AU - Cheong, Hee Jin. AU - Kim, Yang Soo. AU - Park, Yeon Joon. AU - Kim, Woo Joo. AU - Woo, Jun Hee. AU - Lee, Kyung Won. AU - Kang, Moon Won. AU - Choo, Youn Sung. PY - 2002/12. Y1 - 2002/12. N2 - Gemifloxacin is an enhanced-affinity fluoroquinolone with broad-spectrum antibacterial activity. In Korea, resistant bacteria are relatively more prevalent than in other industrialized countries. In this study, we studied the in vitro activities of gemifloxacin, gatifloxacin, moxifloxacin, levofloxacin, ciprofloxacin, and other commonly used antimicrobial agents against 1,689 bacterial strains isolated at four Korean university hospitals during 1999-2000. Minimum inhibitory concentrations (MICs) were determined using the agar dilution method of National Committee for Clinical Laboratory Standards. Gemifloxacin had the lowest MICs for the respiratory pathogens: 90% of ...
https://yonsei.pure.elsevier.com/en/publications/in-vitro-activity-of-gemifloxacin-against-recent-clinical-isolate
Update to CDCs Sexually Transmitted Diseases Treatment Guidelines, 2010: Oral Cephalosporins No Longer a Recommended Treatment...Update to CDCs Sexually Transmitted Diseases Treatment Guidelines, 2010: Oral Cephalosporins No Longer a Recommended Treatment...
GISP is a CDC-supported sentinel surveillance system that has monitored N. gonorrhoeae antimicrobial susceptibilities since 1986, and is the only source in the United States of national and regional N. gonorrhoeae antimicrobial susceptibility data. During September-December 2011, CDC and five external GISP principal investigators, each with N. gonorrhoeae-specific expertise in surveillance, antimicrobial resistance, treatment, and antimicrobial susceptibility testing, reviewed antimicrobial susceptibility trends in GISP through August 2011 to determine whether to update CDCs current recommendations (2) for treatment of uncomplicated gonorrhea. Each month, the first 25 gonococcal urethral isolates collected from men attending participating STD clinics (approximately 6,000 isolates each year) were submitted for antimicrobial susceptibility testing. The minimum inhibitory concentration (MIC), the lowest antimicrobial concentration that inhibits visible bacterial growth in the laboratory, is used ...
https://medspecial.ru/news/1/780/
Evaluation of Polymerase Chain Reaction for Direct Detection of Streptococcus Pneumoniae in Clinical Samples & Antimicrobial...Evaluation of Polymerase Chain Reaction for Direct Detection of Streptococcus Pneumoniae in Clinical Samples & Antimicrobial...
Abstract:. Introduction: Streptococcus pneumoniae (S.pneumoniae) is an important cause of morbidity and mortality in people of extreme age. Drug resistant pneumococci are emerging and causing treatment failure. In the present study we evaluated Polymerase Chain Reaction (PCR) for rapid detection of S. pneumoniae directly from the clinical samples and antimicrobial susceptibilities of the culture isolates Material & methods: A total of 90 clinical samples from sterile sites were cultured. Direct detection of S.pneumoniae from the samples was done using PCR. The isolates were tested for antimicrobial susceptibility by disc diffusion method and Minimum Inhibitory Concentration (MIC) of penicillin was determined by microbroth dilution method. Results: Out of 90 samples 34 were positive for S. pneumoniae by PCR and 23 samples showed growth in culture. Of these 23 isolates, disc diffusion method showed that 61%, 0%, 13%, 35%, 83%, 4.3%, 0% of the isolates were resistant to penicillin, erythromycin, ...
https://ijrhs.org/article/2017/5/4-5
In vitro Evaluation of Biofield Treatment on Enterobacter cloacae: Impact on Antimicrobial Susceptibility and Biotype - Trivedi...In vitro Evaluation of Biofield Treatment on Enterobacter cloacae: Impact on Antimicrobial Susceptibility and Biotype - Trivedi...
This research work investigated the influence of biofield treatment on Enterobacter cloacae (ATCC 13047) against antimicrobial susceptibility. Two sets of ATCC samples were taken in this experiment and denoted as A and B. ATCC A sample was revived and divided into two parts Gr. I (control) and Gr. II (revived); likewise, ATCC B was labeled as Gr. III (lyophilized). Group II and III were given with biofield treatment. The control and treatment groups of E. cloacae cells were tested with respect to antimicrobial susceptibility, biochemical reactions pattern and biotype number. The result showed significant decrease in the minimum inhibitory concentration (MIC) value of aztreonam and ceftazidime (≤ 8 μg/mL), as compared to control group (≥ 16 μg/mL). It was observed that 9% reaction was altered in the treated groups with respect to control out of the 33 biochemical reactions. Moreover, biotype number of this organism was substantially changed in group II (7731 7376) and group III (7710 3176) ...
https://www.trivedieffect.com/science/in-vitro-evaluation-of-biofield-treatment-on-enterobacter-cloacae-impact-on-antimicrobial-susceptibility-and-biotype/
Apitherapy News: Honey Glycoproteins are a Novel Antibacterial with Broad Spectrum Activity Against Multi-Drug Resistant...Apitherapy News: Honey Glycoproteins are a Novel Antibacterial with Broad Spectrum Activity Against Multi-Drug Resistant...
Here, we used semi-quantitative radial diffusion assay and broth microdilution assay to evaluate susceptibility of a number of multi-drug resistant (MDR) clinical isolates to the MRJP1-contaning honey glycoproteins. The MDR bacterial strains comprised three methicillin-resistant Staphylococcus aureus (MRSA), four Pseudomonas aeruginosa, two Klebsiella pneumoniae, two vancomycin-resistant Enterococci (VRE), and five ESBL identified as one Proteus mirabilis, three E. coli, and one E. coli NDM. Their resistance to different classes of antibiotics was confirmed using automated system Vitek 2. MDR isolates differed in their susceptibility to glps with MIC90 values ranging from 4.8 μg/ml against B. subtilis to 14.4 μg/ml against ESBL K. pneumoniae, Klebsiella spp. ESBL and E. coli and up to 33 μg/ml against highly resistant strains of P. aeruginosa ...
http://apitherapy.blogspot.com/2015/08/honey-glycoproteins-are-novel.html
Salmonella spp. isolates causing bloodstream infections in Latin America: report of antimicrobial activity from the SENTRY...
Recent years have seen a dramatic rise in the incidence and severity of cases of human salmonellosis, in addition, multidrug resistant strains have arisen. the objective of this study as to characterize the antimicrobial susceptibility profile of Salmonella spp. clinical isolates collected from Latin American medical centers as part of the SENTRY Antimicrobial Surveillance System. A total of 144 bloodstream Salmonella spp. isolates were collected between 1997 and 2000. the susceptibility to diverse antimicrobial agents was tested by broth microdilution techniques according to the NCCLS recommendations. the Salmonella spp. strains were more frequently collected from adult patients (67.0%; 21-60 years) and isolated from Chile (28.5%) , Brazil (25.0%) , Mexico , Colombia ( 11,8%). Ampicillin (MIC50, 1 mug/ml) showed good in vitro activity (92.4% susceptibility). Meropenem (MIC50. 0.06 mug/ml) and gatifloxacin (MIC50, 0.03 mug/ml) were the most Potent compounds against the Salmonella spp. isolates ( ...
http://repositorio.unifesp.br/handle/11600/27028
Antimicrobial susceptibility profiles of Gram-negative bacilli isolated from patients with hepatobiliary infections in Taiwan:...
TY - JOUR. T1 - Antimicrobial susceptibility profiles of Gram-negative bacilli isolated from patients with hepatobiliary infections in Taiwan. T2 - Results from the Study for Monitoring Antimicrobial Resistance Trends (SMART), 2006-2010. AU - Toh, Han Siong. AU - Chuang, Yin Ching. AU - Huang, Chi Chang. AU - Lee, Yu Lin. AU - Liu, Yuag Meng. AU - Ho, Cheng Mao. AU - Lu, Po Liang. AU - Liu, Chun Eng. AU - Chen, Yen Hsu. AU - Wang, Jen Hsien. AU - Ko, Wen Chien. AU - Yu, Kwok Woon. AU - Liu, Yung Ching. AU - Chen, Yao Shen. AU - Tang, Hung Jen. AU - Hsueh, Po Ren. PY - 2012/6. Y1 - 2012/6. N2 - We investigated the trends in antimicrobial resistance among species of Gram-negative bacilli isolated from patients with hepatobiliary tract infections in Taiwan during the period 2006-2010 as part of the Study for Monitoring Antimicrobial Resistance Trends (SMART). During the study period, 1032 isolates of Gram-negative bacilli that had been collected from patients with hepatobiliary infections were ...
https://tmu.pure.elsevier.com/en/publications/antimicrobial-susceptibility-profiles-of-gram-negative-bacilli-is
In vitro activity of tigecycline, a new glycylcycline, tested against 1,326 clinical bacterial strains isolated from Latin...
The in vitro activity of tigecycline (former GAR-936), a new semisynthetic tetracycline, was evaluated in comparison with tetracycline and other antimicrobial agents. MATERIAL AND METHODS: A total of 1,326 contemporary clinical isolates collected from the Latin American region were collected in 2000-2002 period and tested with microdilution broth according to the CLSI guidelines. The bacterial pathogens evaluated included Staphylococcus aureus (505), Streptococcus pneumoniae (269), coagulase-negative staphylococci (CoNS; 227), Haemophilus influenzae (129), Enterococcus spp. (80), Moraxella catarrhalis (54), beta-haemolytic streptococci (28), viridans group streptococci (26), and Neisseria meningitidis (8) RESULTS:Tigecycline demonstrated excellent activity against all Gram-positive cocci, with 90% of penicillin-resistant S. pneumoniae strains being inhibited at 0.12 µg/mL, while the same isolates had an MIC90 of , 16 µg/mL for tetracycline. All Enterococcus spp. were inhibited at 0.25 µg/mL ...
http://repositorio.unifesp.br/handle/11600/2706
Surveying the Effect of the Phenol Compounds on Antibacterial Activity of Herbal Extracts: In vitro Assessment of Herbal...Surveying the Effect of the Phenol Compounds on Antibacterial Activity of Herbal Extracts: In vitro Assessment of Herbal...
Background & Objectives: Due to increase in  bacterial drug resistance, discovering new antibacterial compounds is really important. The objective of this study is to evaluate the phenol compounds effect on antibacterial activity of herbal extracts of Fasa-Fars province in vitro. Materials & Methods: The antibacterial activity of 26 plants was ...
http://journal.fums.ac.ir/browse.php?a_code=A-10-76-3&slc_lang=en
Microbial Profile and Antimicrobial Susceptibility Pattern of Pus Culture Isolates from a Teaching Tertiary Care Hospital,...Microbial Profile and Antimicrobial Susceptibility Pattern of Pus Culture Isolates from a Teaching Tertiary Care Hospital,...
Pyogenic infections are one of the most common clinical complications following surgery and trauma. Prompt antimicrobial therapy is needed to reduce the morbidity of these infections. Rationale use of antibiotics is the need of the hour to curb the rising antimicrobial resistance. A retrospective study was undertaken to identify the microbial profile with their antibiogram among the pus culture isolates in a teaching tertiary care hospital from January 2017 to June 2017.504 pus culture samples processed at the microbiology lab were analyzed. The isolates from positive pus culture were identified by standard protocols and antimicrobial susceptibility patterns were identified by CLSI guidelines. Positive pus cultures were obtained in 59.92% (302/504). Gram positive bacteria accounted for 31.9 % (97), Gram negative bacteria 67.12% (204) and Candida spp 0.99% (3) with predominance of S. aureus 26.32% (80) followed by E. coli 13.82% (42) and K. pneumoniae 13.49% (41). 17.5% of S. aureus was MRSA and 100%
https://www.ijcmas.com/abstractview.php?ID=7392&vol=7-4-2018&SNo=126
sub-inhibitory concentrations of different antibiotics elicit certain phenotypic and even metabolic observed changes in...sub-inhibitory concentrations of different antibiotics elicit certain phenotypic and even metabolic observed changes in...
Basically, antibiotic compounds play an important role of effector molecules in their natural environments, then their mechanism of action could be seen as using their specific targets as signal relays. For example, tetracyclines binding to the ribosome cause a breakdown in translation that ultimately lead to cell death at high concentrations; but at sub-inhibitory concentrations, the binding to the ribosomes causes a temporary stall in translation that leads to an mRNA build up thereby stabilizing mRNA transcript concentrations in target cells. (Fajardo et al., 2008). Therefore, the action of antibiotic is actually an interesting way of using ribosomes, DNA, RNA, carbohydrates (peptidoglycan) as signal effector receptors and transducers .If antibiotic compounds play the role of effector molecules in their natural environments, then their mechanism of action could be seen as using their specific targets as signal relays. An example, is when tetracyclines binding to the ribosome cause a breakdown ...
https://youmademydayphotography.com/sub-inhibitory-concentrations-of-different-antibiotics-elicit-certain-phenotypic-and-even-metabolic-observed-changes-in-specific-bacterial-species/
Detection of DNA Gyrase Mutation and Multidrug Efflux Pumps Hyperactivity in Ciprofloxacin Resistant Clinical Isolates of...Detection of DNA Gyrase Mutation and Multidrug Efflux Pumps Hyperactivity in Ciprofloxacin Resistant Clinical Isolates of...
Target modification and reduced drug accumulation are the main resistance mechanisms against fluoroquinolone antibiotics in Pseudomonas aeruginosa. We performed a genotypic characterization of three major Mex multidrug efflux pumps (MexAB-OprM, MexXY-OprM and MexCD-OprJ) in ciprofloxacin resistant clinical isolates of P. aeru-ginosa, collected from Tehran, Iran this was followed by sequencing and ...
http://jommid.pasteur.ac.ir/article-1-33-en.html
Peer Evaluation : Antimicrobial Susceptibility Pattern and Biochemical Characteristics of Staphylococcus aureus : Impact of...
Abstract : Study background: Staphylococci are widespread in nature, mainly found on the skin and mucous membranes. Staphylococcus aureus (S. aureus) is the key organism for food poisoning due to massive production of heat stable exotoxins. The current study was attempted to investigate the effect of biofield treatment on antimicrobial susceptibility pattern and biochemical characteristics of S. aureus (ATCC 25923). Methods: S. aureus cells were procured from MicroBioLogics in sealed packs bearing the American Type Culture Collection (ATCC 25923) number and stored according to the recommended storage protocols until needed for experiments. Revived and lyophilized state of ATCC strains of S. aureus were selected for the study. Both revived (Group; Gr. II) and lyophilized (Gr. III) strain of S. aureus were subjected to Mr. Trivedis biofield treatment. Revived treated cells were assessed on day 5 and day 10 while lyophilized treated cells on day 10 only. After biofield treatment both treated cells ...
http://www.peerevaluation.org/read/libraryID:30464
Peer Evaluation : Antimicrobial Susceptibility Pattern and Biochemical Characteristics of Staphylococcus aureus : Impact of...
Abstract : Study background: Staphylococci are widespread in nature, mainly found on the skin and mucous membranes. Staphylococcus aureus (S. aureus) is the key organism for food poisoning due to massive production of heat stable exotoxins. The current study was attempted to investigate the effect of biofield treatment on antimicrobial susceptibility pattern and biochemical characteristics of S. aureus (ATCC 25923). Methods: S. aureus cells were procured from MicroBioLogics in sealed packs bearing the American Type Culture Collection (ATCC 25923) number and stored according to the recommended storage protocols until needed for experiments. Revived and lyophilized state of ATCC strains of S. aureus were selected for the study. Both revived (Group; Gr. II) and lyophilized (Gr. III) strain of S. aureus were subjected to Mr. Trivedis biofield treatment. Revived treated cells were assessed on day 5 and day 10 while lyophilized treated cells on day 10 only. After biofield treatment both treated cells ...
http://peerevaluation.org/read/libraryID:30464
SENTRY antimicrobial surveillance program report: latin american and brazilian results for 1997 through 2001SENTRY antimicrobial surveillance program report: latin american and brazilian results for 1997 through 2001
In addition, data collected in the participating Brazilian centers were analyzed separately from the data of the entire Latin American region (including Brazil). Minimum antimicrobial concentrations that inhibits 50% and 90% of the organism collection (MIC50 and MIC90, respectively) were presented only for the data of the entire region. Isolates collected from bloodstream infections and from lower respiratory tract infections (mainly pneumonia) in hospitalized patients were also analyzed separately (Tables 3, 5, 7 and 9). Two groups of pathogens, streptococci and extended-spectrum (ESBL)-producing strains, were analyzed separately due to their importance in community-acquired and nosocomial-acquired infections, respectively. Table 10 presents the antimicrobial susceptibility of streptococcal species, while Table 11 presents the antimicrobial susceptibility of ESBL-producing E. coli and Klebsiella pneumoniae. Discussion. We made a comprehensive analysis of the Latin American SENTRY Program data ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702004000100004&lng=en&nrm=iso&tlng=en
Prevalence and Antimicrobial Susceptibility Profile of Metallo-β-Lactamase Producing Pseudomonas aeruginosa Isolates at...Prevalence and Antimicrobial Susceptibility Profile of Metallo-β-Lactamase Producing Pseudomonas aeruginosa Isolates at...
Pseudomonas aeruginosa is a major cause of nosocomial infections with high mortality rates. The organism is highly resistant to most classes of drugs used and can develop resistance during treatment. One of the resistance mechanisms of P. aeruginosais is Metallo-β-Lactamase (MBL) production. MBL producing P. aeruginosa is a major health concern given its resistance to almost all available drugs. The prevalence of this resistant strain is unknown since there is no standardized method for testing MBL production. This was a laboratory based cross-sectional prospective study that was carried out from September 2015 to March 2016 at Kenyatta National Hospital. Ninety-nine isolates of P. aeruginosa were collected during the period and tested for antimicrobial susceptibility and isolates found to be resistant to imipenem tested for MBL production. The results indicated high resistance of P. aeruginosa to commonly used drugs. Of the isolates tested 69.7% were resistant to piperacillin, 63.6% were resistant to
https://file.scirp.org/Html/6-2271171_88395.htm
Antimicrobial susceptibility and minimal inhibitory concentration of Pseudomonas aeruginosa isolated from septic ocular surface...Antimicrobial susceptibility and minimal inhibitory concentration of Pseudomonas aeruginosa isolated from septic ocular surface...
The purpose of this study was to evaluate the antibiotic susceptibility profile of Pseudomonas aeruginosa isolated from different animal species with septic ocular surface disease. Sixteen strains of P. aeruginosa were isolated from different species of animals (dog, cat, horse, penguin and brown bear) with ocular surface diseases such as conjunctivitis, keratocojnuctivits sicca and ulcerative keratitis. These isolates were tested against 11 different antimicrobials agents using the Kirby-Bauer disk-diffusion method. Minimum inhibitory concentrations (MICs) were determined using E-tests for two antibiotics (tobramycin and ciprofloxacin) commonly used in veterinary ophthalmology practice. Imipenem was the most effective antibiotic, with 100% of the strains being susceptible, followed by amikacin (87.5%), gentamicin, norfloxacin, gatifloxacin and polymyxin (both with 81.5%of susceptibility). MIC90 of ciprofloxacin was 2 µg/ml and the values found ranged from 0.094 µg/ml to 32 µg/ml. For tobramycin,
https://www.semanticscholar.org/paper/Antimicrobial-susceptibility-and-minimal-inhibitor-Leigue-Montiani-Ferreira/04ff075135c0a3114fc5bcd184f3778622d1849c
Study of routine antimicrobial susceptibility of clinical isolated Brucella melitenesis--《Chinese Journal of Infection Control...Study of routine antimicrobial susceptibility of clinical isolated Brucella melitenesis--《Chinese Journal of Infection Control...
Objective To study antimicrobial resistance of Brucella melitenesis and instruct rational use of antimicrobial agents for clinic.Methods Bacteria were cultured and identified by Bact/Alert 3D and VITEK Ⅱ automicrobic system.Drug susceptibility was detected by E-test method.Results Four strains Brucella melitenesis were isolated from blood of 4 patients with fever and MIC of gentamicin,ampicillin and ciprofloxacin was(0.5)～(0.75 mg/L),(1.5)～(2.0 mg/L) and (4.0)～(8.0 mg/L) respectively.MIC of ceftazidime,amikacin and doxycycline were all above(8.0 mg/L).Conclusion The preferred drug for treating brucellosis is gentamicin or plus ampicillin or ciprofloxacin,or choosing antimicrobial agents according to antimicrobial susceptibility test results.
http://en.cnki.com.cn/Article_en/CJFDTOTAL-GRKZ200601019.htm
New multidrug efflux inhibitors for gram-negative bacteria - Prestwick Chemical LibrariesNew multidrug efflux inhibitors for gram-negative bacteria - Prestwick Chemical Libraries
Active efflux of antibiotics preventing their accumulation to toxic intracellular concentrations contributes to clinically relevant multidrug resistance. Inhibition of active efflux potentiates antibiotic activity, indicating that efflux inhibitors could be used in combination with antibiotics to reverse drug resistance. Expression of ramA by Salmonella enterica serovar Typhimurium increases in response to efflux inhibition, irrespective of the mode of inhibition. We hypothesized that measuring ramA promoter activity could act as a reporter of efflux inhibition. A rapid, inexpensive, and high-throughput green fluorescent protein (GFP) screen to identify efflux inhibitors was developed, validated, and implemented. Two chemical compound libraries were screened for compounds that increased GFP production. Fifty of the compounds in the 1,200-compound Prestwick chemical library were identified as potential efflux inhibitors, including the previously characterized efflux inhibitors mefloquine and ...
https://www.prestwickchemical.com/success-story/new-multidrug-efflux-inhibitors-for-gram-negative-bacteria/
Mutant prevention concentrations of pradofloxacin for susceptible and mutant strains of Escherichia coli with reduced...Mutant prevention concentrations of pradofloxacin for susceptible and mutant strains of Escherichia coli with reduced...
Pharmacodynamic and mutant prevention properties of the fluoroquinolone pradofloxacin (PRA) were measured against a set of 17 Escherichia coli strains carrying no, one or two known mutations conferring reduced fluoroquinolone susceptibility. The strains included susceptible wild-types, isogenic constructed mutants, isogenic selected mutants and clinical isolates. The effectiveness of PRA was determined with regard to preventing the selection of resistant mutants, using static and changing concentrations of drug. Ciprofloxacin was used as a reference drug. Minimum inhibitory concentrations (MICs) and mutant prevention concentrations (MPCs) of PRA for the susceptible wild-type strains were in the range 0.012-0.016 mg/L and 0.2-0.3 mg/L, respectively, giving a mean +/- standard deviation mutant prevention index (MPI=MPC/MIC) of 17.7 +/- 1.1. The mean MPI PRA of the 14 mutant strains was 19.2 +/- 12, and the mean MPI across all 17 strains was 18.9 +/- 10.8. In an in vitro kinetic model in which PRA ...
http://uu.diva-portal.org/smash/record.jsf?pid=diva2:766012
In Vitro Activities of the Glycylcycline GAR-936 against Gram-Positive Bacteria | Antimicrobial Agents and ChemotherapyIn Vitro Activities of the Glycylcycline GAR-936 against Gram-Positive Bacteria | Antimicrobial Agents and Chemotherapy
Against streptococci other than pneumococci, the intrinsic potency of GAR-936, based on a comparison of MIC50s, was equivalent or slightly superior to that of minocycline. Median (modal) MICs for GAR-936 and minocycline were 0.06 (0.06) and 0.12 (0.12) μg/ml, respectively. However, all streptococcal isolates, including strains resistant to doxycycline or minocycline, were inhibited by GAR-936 at ≤0.25 μg/ml.. For pneumococci, the results shown in Table 1 were obtained by agar dilution. The activity of GAR-936 against 60 strains ofStreptococcus pneumoniae, half of which were not susceptible to penicillin, was also evaluated by microdilution. The MIC50 and MIC90 were 0.03 and 0.06 μg/ml. These were within 1 dilution of agar dilution results. Individually, microdilution results were 2 dilutions lower than the agar dilution results for 11 strains, 1 dilution lower for 27, equivalent for 13, and 1 dilution greater for 4. For S. pneumoniae ATCC 49619, the broth microdilution result was 1 dilution ...
https://aac.asm.org/content/44/8/2225?ijkey=29d2766495efbec2c297fe443b5978da5e20d1e2&keytype2=tf_ipsecsha
Global Health & Pharma - New Antimicrobial Tildipirosin LaunchedGlobal Health & Pharma - New Antimicrobial Tildipirosin Launched
New macrolide expands treatment options for bovine respiratory disease (BRD) in cattle.. The new antimicrobial tildipirosin is now available on veterinary microbroth dilution susceptibility plates, enabling veterinary microbiology laboratories to perform antimicrobial susceptibility testing on organisms that cause bovine respiratory disease (BRD) in beef and non-lactating dairy cattle.. The Thermo Scientific Sensititre System, recognized for including one of the largest and most up-to-date selections of antimicrobials for susceptibility testing, with more than 40 veterinary-specific antimicrobials, is now the first to offer tildipirosin on microbroth dilution susceptibility plates. Tildipirosin is available globally on Sensititre veterinary custom plates, and it will be featured on additional standard plates in the future. A variety of other species-specific, standard diagnostic formats are also available for applications related to avian and poultry, bovine and porcine, companion animals, ...
https://www.ghp-news.com/2016-new-antimicrobial-tildipirosin-launched
Journal of Medicinal Plants Research - in vitro antimicrobial activity of “antibact†, an herbal medicinal product against...Journal of Medicinal Plants Research - in vitro antimicrobial activity of “antibact†, an herbal medicinal product against...
In vitro antimicrobial activities of ethanol and aqueous “Antibact”, herbal products consisting of a combination of the leaves and branches of four different plants were evaluated against twenty one pathogenic bacteria. Saponins, reducing sugars, phenolics, polyuronides, and triterpenes were the major phyto-constituents of both the aqueous and ethanol “Antibact”. The LD50 analysis revealed the products were safe (LD50>5000 mg/kg bodyweight) for in vivo use. All the isolates (100%) were resistant to at least five of the 12 antibiotics used in the study. In total, the aqueous “Antibact” inhibited the growth of 5 out of the 21 (23.81%) microbes used with an average zone of inhibition of 9.73 ± 0.35 mm. Thirteen (61.90%) out of the 21 microbes used were susceptible to the ethanol “Antibact”, registering an average inhibition zone of 10.80 ± 0.18 mm. In the case of the minimum inhibitory concentration (MIC), the aqueous “Antibact&rdquo
https://academicjournals.org/journal/JMPR/article-abstract/A2692C951781
Welcome to CDC stacksWelcome to CDC stacks
Clinical antimicrobial susceptibility breakpoints are used to predict the clinical outcome of antimicrobial treatment. In contrast, microbiologic breakpoints are used to identify isolates that may be categorized as susceptible when applying clinical breakpoints but harbor resistance mechanisms that result in their reduced susceptibility to the agent being tested. Currently, the National Committee for Clinical Laboratory Standards (NCCLS) guidelines utilize clinical breakpoints to characterize the activity of the fluoroquinolones against Streptococcus pneumoniae. To determine whether levofloxacin breakpoints can identify isolates that harbor recognized resistance mechanisms, we examined 115 S. pneumoniae isolates with a levofloxacin MIC of >2 mg/mL for first-step parC mutations. A total of 48 (59%) of 82 isolates with a levofloxacin MIC of 2 mg/mL, a level considered susceptible by NCCLS criteria, had a first-step mutation in parC. Whether surveillance programs that use levofloxacin data can ...
https://stacks.cdc.gov/view/cdc/14124/Email
Yeast-like filamentous fungi: Molecular identification and in vitro susceptibility study<...
TY - JOUR. T1 - Yeast-like filamentous fungi. T2 - Molecular identification and in vitro susceptibility study. AU - Esposto, Maria Carmela. AU - Prigitano, Anna. AU - Lo Cascio, Giuliana. AU - Ossi, Cristina. AU - Grancini, Anna. AU - Cavanna, Caterina. AU - Lallitto, Fabiola. AU - Tejada, Milvana. AU - Bandettini, Roberto. AU - Mularoni, Alessandra. AU - Tortorano, Anna Maria. PY - 2019/10/1. Y1 - 2019/10/1. N2 - Yeast-like filamentous fungi, collected in Italy from 1985 to 2018, were submitted to molecular identification and antifungal susceptibility testings. Clinical isolates were identified as Magnusiomyces capitatus (28), M. clavatus (18), and Geotrichum candidum (2). M. clavatus was prevalent among blood isolates (18/24), M. capitatus among isolates from other biological materials. The intrinsic echinocandin resistance was confirmed. Both species had low minimum inhibitory concentrations (MICs) of itraconazole, posaconazole, and voriconazole, while M. clavatus had lower MIC of flucytosine ...
https://moh-it.pure.elsevier.com/en/publications/yeast-like-filamentous-fungi-molecular-identification-and-in-vitr-6
Mueller Hinton Agar I | NEOGENMueller Hinton Agar I | NEOGEN
Mueller Hinton Agar I is used for antimicrobial sensitivity testing by the disc diffusion method and is not intended for use in the diagnosis of disease or other conditions in humans.. A medium for antimicrobial sensitivity testing by the disc diffusion method. This medium, used in the technique of Bauer and Kirby, has been adopted by the Clinical and Laboratory Standard Institute (CLSI), formerly National Committee for Clinical Laboratory Standards (NCCLS) in the USA as the definitive method for susceptibility testing. The medium has a very low thymine and thymidine content, making it suitable for trimethoprim and sulphonamide testing, controlled to ensure correct zone sizes with aminoglycoside and tetracyline antibiotics. The medium was originally formulated as a heat labile protein free medium for the isolation of pathogenic Neisseriaceae.. ...
https://www.neogen.com/categories/microbiology/mueller-hinton-agar-1/?recommendationId=1383806683401
A multicenter study to evaluate ceftaroline breakpoints: Performance in an area with high prevalence of methicillin- resistant...A multicenter study to evaluate ceftaroline breakpoints: Performance in an area with high prevalence of methicillin- resistant...
ABSTRACT Ceftaroline (CPT) is a broad-spectrum agent with potent activity against methicillin-resistant Staphylococcus aureus (MRSA). The sequence type 5 (ST5) Chilean-Cordobés clone, associated with CPT nonsusceptibility, is dominant in Chile, a region with high rates of MRSA infections. Here, we assessed the in vitro activity of CPT against a collection of MRSA isolates collected between 1999 and 2018 from nine hospitals (n 320) and community settings (n 41) in Santiago, Chile, and evaluated performance across testing methodologies. We found that our hospitalassociated isolates exhibited higher CPT MIC distributions (MIC50 and MIC90 of 2 mg/liter) than the community isolates (MIC50 and MIC90 of 0.5 mg/liter), a finding that was consistent across time and independent of the culture source. High proportions (64%) of isolates were CPT nonsusceptible despite the absence of CPT use in Chile. Across methodologies, the Etest underestimated the MIC relative to the gold standard broth microdilution ...
https://repositorio.unbosque.edu.co/handle/20.500.12495/2020
mueller hinton agar plates price
Recommended for antimicrobial susceptibility testing of common, rapidly growing bacteria. Buy low price Mueller Hinton Agar Plate in Malakpet, Hyderabad. See My Price. Mueller Hinton Agar with Blood, 15x100mm plate, order by the package of 10, by Hardy Diagnostics (Mueller Hinton Agar with 5% Sheep Blood) For disk diffusion sensitivity testing of Streptococcus spp. Plate Size. Ambient shipping conditions. If you are viewing this page as a nonregistered user, the price(s) displayed is List Price. Mueller Hinton Medium Culture Plates Agar HARDY DIAGNOSTICS. ... Mueller Hinton II Agar Plates, Pkg of 20, 150 mm #M0026: Download SDS: SDS Request. 1 Product Result , Match Criteria: Product Name, Description 97580 ; for microbiology, NutriSelect ™ Plus; Millipore pricing. Mueller Hinton Agar Plate offered by Labline Trading Company is available with multiple payment options and easy delivery. Micro BCA Protein Assay Kit, 100-mm Mueller-Hinton agar plates, and Mueller-Hinton liquid broth were ...
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Surface plasmon biosensing technology for antimicrobial susceptibility test - References | InTechOpenSurface plasmon biosensing technology for antimicrobial susceptibility test - References | InTechOpen
Surface plasmon biosensing technology for antimicrobial susceptibility test - References | InTechOpen, Published on: 2011-07-19. Authors: How Foo Chen, Chi-Hung Lin, Chun-Yao Su, et
https://www.intechopen.com/books/references/biosensors-for-health-environment-and-biosecurity/surface-plasmon-biosensing-technology-for-antimicrobial-susceptibility-test
Antibiotics | Free Full-Text | Antimicrobial Activity of Five Apitoxins from Apis mellifera on Two Common Foodborne Pathogens ...Antibiotics | Free Full-Text | Antimicrobial Activity of Five Apitoxins from Apis mellifera on Two Common Foodborne Pathogens ...
Antimicrobial resistance is one of today’s major public health challenges. Infections caused by multidrug-resistant bacteria have been responsible for an increasing number of deaths in recent decades. These resistant bacteria are also a concern in the food chain, as bacteria can resist common biocides used in the food industry and reach consumers. As a consequence, the search for alternatives to common antimicrobials by the scientific community has intensified. Substances obtained from nature have shown great potential as new sources of antimicrobial activity. The aim of this study was to evaluate the antimicrobial activity of five bee venoms, also called apitoxins, against two common foodborne pathogens. A total of 50 strains of the Gram-negative pathogen Salmonella enterica and 8 strains of the Gram-positive pathogen Listeria monocytogenes were tested. The results show that the minimum inhibitory concentration (MIC) values were highly influenced by the bacterial genus. The MIC values ranged from
https://www.mdpi.com/2079-6382/9/7/367/htm
Molecular Characterization of Extended Spectrum β-Lactamase Genes in Clinical E. coli IsolatesMolecular Characterization of Extended Spectrum β-Lactamase Genes in Clinical E. coli Isolates
Extended Spectrum Beta-Lactamases (ESBLs) encoding genes (TEM, SHV and OXA) were amplified from multidrug resistance E. coli. The multidrug resistance E. coli isolates from different clinical sources were documented to be plasmid encoded and resistance against β-lactam and cephalosporin. Conventional laboratory analysis showed that seventy percent (70%) of the selected multidrug resistant clinical isolates were ESBLs positive, showing a ≥5 mm increase in zone diameter for either antibiotics compared to its zone when tested alone. The antibiotic susceptibility result showed that 100% of the isolates were resistant to amoxicillin-clavulanic acid, amoxicillin, cefuroxime and ampicillin-sulbactam while 90% of the isolates were resistant to ceftazidine and tetracycline, 80% to ofloxacin, 70% to ceftriazon, nalidixic acid, cefalexin, 60% to ciprofloxacin, 50% to nitrofurantoin, 40% to chloramphenicol and 20% to gentamicine. The multiplex PCR with primers TEM (931bp), SHV (868), OXA-2 (478), aac(3)-IIa (900
https://m.scirp.org/papers/44697
Microbiology Society Journals | In vitro and in vivo assessments of Rhodomyrtus tomentosa leaf extract as an alternative anti...Microbiology Society Journals | In vitro and in vivo assessments of Rhodomyrtus tomentosa leaf extract as an alternative anti...
Purpose. Rhodomyrtustomentosa is a Thai medicinal plant that has been attracting attention for its remarkable antibacterial properties against Gram-positive pathogenic bacteria. The purpose of this study was to evaluate the antibacterial properties of R. tomentosa leaf extract against Streptococcus agalactiae and Streptococcus iniae isolated from infected tilapia. Methodology. The anti-streptococcal activity of R. tomentosa was determined using broth microdilution assays. Results. The extract demonstrated strong antibacterial activity against the fish pathogens, with minimum inhibitory concentrations (MICs) ranging from 7.8‒62.5 µg ml−1. It was found to possess a dose-dependent bacteriostatic effect on this organism. Scanning electron microscopy revealed irregular and long chains of swollen cells, as well as corkscrew shapes andincomplete separation of cell division of S. agalactiae cells following the treatment at sub-MIC. Moreover, S. agalactiae cells pre-treated with the extract became more
http://jmm.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.000453
Comparative MIC evaluation of a generic ceftriaxone by broth microdilution on clinically relevant isolates from an academic...Comparative MIC evaluation of a generic ceftriaxone by broth microdilution on clinically relevant isolates from an academic...
LOWMAN, Warren et al. Comparative MIC evaluation of a generic ceftriaxone by broth microdilution on clinically relevant isolates from an academic hospital complex in South Africa. SAMJ, S. Afr. med. j. [online]. 2012, vol.102, n.2, pp.102-103. ISSN 2078-5135.. We evaluated the in vitro microbiological efficacy of a generic ceftriaxone product against several clinically significant organisms collected from sterile sites. The minimum inhibitory concentration (MIC) of each was determined simultaneously with the reference and the generic ceftriaxone product. Comparative analysis of MICs between the two products for each isolate was performed using both categorical (interpretive) agreement and essential (actual MIC value) agreement. A total of 260 isolates were tested. Overall, there was categorical agreement of 98.9% and essential agreement of 95.8%. The categorical agreement for all isolates (96.7 - 100%) accorded with international standards, as no very major errors were seen and the major error ...
http://www.scielo.org.za/scielo.php?script=sci_abstract&pid=S0256-95742012000200024&lng=en&nrm=iso
Equine lymphangitisEquine lymphangitis
... microbial culture and sensitivity testing should be performed, so the most efficacious antibiotic can be chosen. However, ... Aspiration of a fluid sample for microbial culture is worth trying, but is often unrewarding. The mainstays of treatment are ... OIE Manual of Diagnostic Tests and Vaccines for Terrestrial Animals 2004 Chapter 2.5.13, [1] . RR Pascoe, DC Knottenbelt, ...
https://en.wikipedia.org/wiki/Equine_lymphangitis
Antibiotic sensitivity testingAntibiotic sensitivity testing
If the antibiotic inhibits microbial growth, a clear ring, or zone of inhibition, is seen around the disc. The bacteria are ... Antibiotic sensitivity testing or antibiotic susceptibility testing is the measurement of the susceptibility of bacteria to ... in which the choice of antibiotic is based on knowledge of the organism and its sensitivities. Sensitivity testing usually ... Antibiotic sensitivity testing is also conducted at a population level in some countries as a form of screening. This is to ...
https://en.wikipedia.org/wiki/Antibiotic_sensitivity_testing
University of the Philippines Los Baños College of Veterinary MedicineUniversity of the Philippines Los Baños College of Veterinary Medicine
... water microbial analysis, blood parasite examination, antibiotic sensitivity test and the like; (3) Experimental Animal Farm ...
https://en.wikipedia.org/wiki/University_of_the_Philippines_Los_Baños_College_of_Veterinary_Medicine
List of MeSH codes (E05)List of MeSH codes (E05)
... limulus test MeSH E05.200.875.220 - colony count, microbial MeSH E05.200.875.595 - microbial sensitivity tests MeSH E05.200. ... microbial sensitivity tests MeSH E05.337.550.400.800 - serum bactericidal test MeSH E05.337.550.600 - parasitic sensitivity ... sensitivity and specificity MeSH E05.318.780.800.650 - predictive value of tests MeSH E05.318.780.800.750 - roc curve MeSH ... neutralization tests MeSH E05.196.922.750 - potentiometry MeSH E05.196.922.875 - skin test end-point titration MeSH E05.196. ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(E05)
Disk diffusion testDisk diffusion test
Kirby-Bauer test, disc-diffusion antibiotic susceptibility test, disc-diffusion antibiotic sensitivity test and KB test) is a ... In this setting, it is not the bacterial strain that must be characterized, but a test extract (e.g. a plant or microbial ... Antibiotic sensitivity testing Double-disk diffusion test Etest EUCAST (January 2021). "Antimicrobial susceptibility testing: ... Bauer AW, Perry DM, Kirby WM (August 1959). "Single-disk antibiotic-sensitivity testing of staphylococci: An analysis of ...
https://en.wikipedia.org/wiki/Disk_diffusion_test
EtestEtest
... (previously known as the Epsilometer test) is a way of determining antimicrobial sensitivity by placing a strip ... For some microbial and antimicrobial combinations, the results can be used to determine a minimum inhibitory concentration (MIC ... The time taken for a plate to be ready depends on the bacterium that is being tested, and the conditions of the agar plate. The ... Etest can be used with many different kinds of AST agar medium as long as the medium supports good growth of the test organism ...
https://en.wikipedia.org/wiki/Etest
List of MeSH codes (G01)List of MeSH codes (G01)
... parasitic sensitivity tests MeSH G01.273.738 - photobiology MeSH G01.273.789 - radiobiology MeSH G01.273.866 - sociobiology ... microbial MeSH G01.273.540.460 - industrial microbiology MeSH G01.273.540.553 - mycology MeSH G01.273.540.859 - virology MeSH ... microbial MeSH G01.273.343.335 - genetics, population MeSH G01.273.343.350 - genomics MeSH G01.273.343.350.700 - proteomics ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(G01)
Rapid strep testRapid strep test
Microbial culture from a throat swab is a reliable and affordable alternative to an RST which has high sensitivity and ... The sensitivity of lateral flow RSTs is somewhat low at 65% to 80%. Therefore, a negative result from such a test cannot be ... The rapid strep test (RST) is a rapid antigen detection test (RADT) that is widely used in clinics to assist in the diagnosis ... Screening (medicine) Diagnostic test Mersch, John (20 February 2015). "Rapid strep test". MedicineNet.com. Retrieved 4 November ...
https://en.wikipedia.org/wiki/Rapid_strep_test
Blood cultureBlood culture
MALDI-TOF has been explored as a rapid antimicrobial sensitivity testing method; principles involve measuring microbial growth ... To perform the test, blood is drawn into bottles containing a liquid formula that enhances microbial growth, called a culture ... Culturing remains necessary in order to carry out full antimicrobial sensitivity testing. Antimicrobial treatment of ... Some biochemical and immunologic tests can be performed directly on positive blood cultures, such as the tube coagulase test ...
https://en.wikipedia.org/wiki/Blood_culture
National TB Elimination Program (India)National TB Elimination Program (India)
... and Drug Susceptibility Testing are available at C&DST(Culture and Drug Sensitivity Testing) Labs are located at a few select ... Based on the nature of anti-microbial resistance to the disease different treatment regimen are offered through the program. ... test sensitivity as well. Cartridge Based Nucleic Acid Amplification Test (CBNAAT) using the GeneXpert Platform, and TruNat are ... rapid molecular tests for TB diagnosis and Rifampicin resistance detection . This test is the first choice of diagnostic test ...
https://en.wikipedia.org/wiki/National_TB_Elimination_Program_(India)
FluorochromasiaFluorochromasia
... in vitro chemo sensitivity testing of tumors, and fluorochrome intercellular translocation. It has been applied with plants, ... "Applicability of the fluorescein diacetate method of detecting active bacteria in freshwater." Microbial Ecology 10.2 (1984): ... Eugene A. Woltering, Tumor Chemosensitivity Testing An Evolving Technique. Lab Medicine 21, 82-84, 1990. (Cell biology). ... Fluorochromasia has many applications including histocompatibility testing, measurement of cytotoxic antibodies, ...
https://en.wikipedia.org/wiki/Fluorochromasia
Microtox bioassayMicrotox bioassay
This sensitive and rapid testing analyser has the ability to detect microbial contamination, as well as more than 2,700 ... The sensitivity of the reagent may become altered after the recommended time period. Microtox Osmotic Adjustment Solution (MOAS ... There are five major Microtox tests including the Basic Test, the 100% Test, the Solid Phase Test, the Comparison Test, and the ... Of these five tests, three are used for sediment and soil testing including the Basic Test, the 100% Test and the Solid-Phase ...
https://en.wikipedia.org/wiki/Microtox_bioassay
Smell as evidence of diseaseSmell as evidence of disease
Their sensitivity was lower in comparison to nucleic acid amplification tests (80%) and with culture (60-70%). The rats were ... Duffy, Emer; Morrin, Aoife (2019-02-01). "Endogenous and microbial volatile organic compounds in cutaneous health and disease ... VOCs are currently deemed as noninvasive diagnostic biomarkers with the potential for point-of-care (POC) testing and long-term ... They were also capable of surveilling C. difficile in the environment with 92.3% sensitivity and 95.4% specificity for both ...
https://en.wikipedia.org/wiki/Smell_as_evidence_of_disease
List of MeSH codes (H01)List of MeSH codes (H01)
... parasitic sensitivity tests MeSH H01.158.273.738 - photobiology MeSH H01.158.273.789 - radiobiology MeSH H01.158.273.943 - ... microbial genetics MeSH H01.158.273.343.335 - population genetics MeSH H01.158.273.343.350 - genomics MeSH H01.158.273.343. ... predictive value of tests MeSH H01.548.832.672.617 - proportional hazards models MeSH H01.548.832.672.734 - risk MeSH H01.548. ... hardness tests MeSH H01.671.368 - health physics MeSH H01.671.469 - lubrication MeSH H01.671.493 - magnetics MeSH H01.671. ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(H01)
Fastidious organismFastidious organism
This means that the sensitivity of the test is less than perfect. So, for example, culture alone may not be enough to help a ... Some microbial species' requirements for life include not only particular nutrients but chemical signals of various kinds, some ... The same problem also causes confounding errors in DNA testing in forensics; tiny amounts of one's DNA can end up almost ... So a positive on those tests can sometimes be a false positive regarding the important distinction of infection versus just ...
https://en.wikipedia.org/wiki/Fastidious_organism
Urinary bladderUrinary bladder
The urine specimen may be also sent for microbial culture and sensitivity to assess if a particular bacteria grows in the urine ... and identify its antibiotic sensitivities. Sometimes, additional investigations may be requested. These might include testing ... Urodynamic testing can help to explain the symptoms. An underactive bladder is the condition where there is a difficulty in ... Urodynamic testing can help to explain the symptoms. All mammals have a urinary bladder. This structure begins as an embryonic ...
https://en.wikipedia.org/wiki/Urinary_bladder
PICRUStPICRUSt
Additional tests examined sensitivity to errors in phylogenetic inference, lack of genomic data, and the accuracy of the ... The tool serves in the field of metagenomic analysis where it allows inference of the functional profile of a microbial ... Langille et al tested the accuracy of this genome prediction step using leave-one-out cross validation on the input set of ... Test datasets included human microbiome samples from the Human Microbiome Project, soil samples, diverse mammalian samples, and ...
https://en.wikipedia.org/wiki/PICRUSt
OleandrinOleandrin
This test is slower and has a lower sensitivity than digoxin immunoassay (Digoxin III). A direct analytic technique like liquid ... Enzyme and Microbial Technology. 41 (3): 331-66. doi:10.1016/j.enzmictec.2007.02.015. Wang, Xiaomin; Plomley, Jeffry B.; Newman ...
https://en.wikipedia.org/wiki/Oleandrin
Lab-on-a-chipLab-on-a-chip
Testing the safety and efficacy of new drugs, as with lung on a chip Total analysis system Volpatti, L. R.; Yetisen, A. K. (Jul ... A gold standard for diagnosing bacteriuria (urinary tract infections) is microbial culture. A recent study based on lab-on-a- ... In developed nations, the most highly valued traits for diagnostic tools include speed, sensitivity, and specificity; but in ... One of the most prominent and well known LOC devices to reach the market is the at home pregnancy test kit, a device that ...
https://en.wikipedia.org/wiki/Lab-on-a-chip
Ruth Ella MooreRuth Ella Moore
These reactions were not similar to those described in the Dick test and the Schick test, both of which were used to detect ... Briscoe, M. S.; Moore, Ruth E.; Puckett, Dewey E. (December 1963). "The Sensitivity to Antibiotics of Microorganisms Isolated ... The Microbial Menagerie. July 29, 2020. Retrieved April 6, 2021. "Ruth Ella Moore-Bacteriologist-UCI webfiles". The Faces of ... see Dick test and Schick test). Additionally, no toxins had been identified from L. acidophilus, leading Dr. Moore to conclude ...
https://en.wikipedia.org/wiki/Ruth_Ella_Moore
Halostagnicola larseniiHalostagnicola larsenii
Antibiotic sensitivity and resistance was determined using the agar diffusion test in which paper discs saturated with ... "Simplified protocols for the preparation of genomic DNA from bacterial cultures." Molecular microbial ecology manual 1.1 (1999 ... Tests revealed this organism is oxidase positive and catalase negative. Halostagnicola larsenii is a halophilic, neutrophilic, ... Growth substrates were determined through the use of the isolation medium, which contained the substrate being tested along ...
https://en.wikipedia.org/wiki/Halostagnicola_larsenii
Co-stimulationCo-stimulation
This complex is called the B cell coreceptor complex for such sensitivity enhancement to the antigen. Abatacept (Orencia) is a ... Belatacept is another novel molecule which is being tested as an anti-rejection medication for use in renal transplantation. A ... which continue to bind to microbial surface, B cells express complement receptor CR2 (CD21) to bind to iC3b, C3dg, or C3d. This ...
https://en.wikipedia.org/wiki/Co-stimulation
Mel RosenbergMel Rosenberg
Rosenberg, Mel (2006). "Microbial adhesion to hydrocarbons: twenty-five years of doing MATH". FEMS Microbiology Letters. 262 (2 ... Kozlovsky, A; Gordon, D; Gelernter, I; Rosenberg, M; Rosenberg, M (1994). "Correlation between the BANA test and oral malodor ... Rosenberg, M.; Kulkarni, G.V.; Bosy, A.; McCulloch, C.A. (1991). "Reproducibility and sensitivity of oral malodor measurements ... He is also the inventor or co-inventor of several other patents, including two microbial inoculation tools, the Quadloop and ...
https://en.wikipedia.org/wiki/Mel_Rosenberg
Water qualityWater quality
After a natural disaster, as far as water quality testing is concerned, there are widespread views on the best course of action ... Rainfall following a dry period can lead to microbial contamination of drinking water in piped water supplies. Floods intensify ... Biosensors have the potential for "high sensitivity, selectivity, reliability, simplicity, low-cost and real-time response". ... Sampling of water for physical or chemical testing can be done by several methods, depending on the accuracy needed and the ...
https://en.wikipedia.org/wiki/Water_quality
Pollution-induced community tolerancePollution-induced community tolerance
... sediment microbial diversity following chronic copper-exposure induce community copper-tolerance without increasing sensitivity ... Co-tolerance is the ability of an organism to develop a tolerance to a certain toxicant in short-term tests, and obtain that ... "Comparing the effect of Cu-based fungicides and pure Cu salts on microbial biomass, microbial community structure and bacterial ... Studies on soil microbial communities have been conducted in industrial and agricultural contexts (see the review of Boivin et ...
https://en.wikipedia.org/wiki/Pollution-induced_community_tolerance
ExoenzymeExoenzyme
Cell-free use of microbial exoenzymes as agents of bioremediation is also possible although their activity is often not as ... McGuffie EM, Fraylick JE, Hazen-Martin DJ, Vincent TS, Olson JC (July 1999). "Differential sensitivity of human epithelial ... "Lab 8: Identification of Bacteria Through Biochemical Testing". Biol 230 Lab Manual. Retrieved 9 December 2013. Erhardt M, ... Pandey A, Nigam P, Soccol CR, Soccol VT, Singh D, Mohan R (2000). "Advances in microbial amylases". Biotechnol. Appl. Biochem. ...
https://en.wikipedia.org/wiki/Exoenzyme
GonorrheaGonorrhea
In those failing initial treatment, culture should be done to determine sensitivity to antibiotics. Tests that use PCR (aka ... and gonococci and commensal Neisseria species can coexist for long time periods in the pharynx and share anti-microbial ... Diagnosis is by testing the urine, urethra in males, or cervix in females. Testing all women who are sexually active and less ... All people testing positive for gonorrhea should be tested for other sexually transmitted diseases such as chlamydia, syphilis ...
https://en.wikipedia.org/wiki/Gonorrhea
Monolithic HPLC columnMonolithic HPLC column
... advanced forensic testing in criminal trials, better environmental monitoring, and faster returns on medical tests. In the ... The sensitivity of multidimensional LC is therefore 2000 times greater than that of conventional HPLC. The liquid ... His group studied gut microbial metabolic profiles and were able to see distinct differences in reactions to drug toxicity and ... It is used in conjunction with online databases for rapid analysis of compounds in tests for blood alcohol, cause of death, ...
https://en.wikipedia.org/wiki/Monolithic_HPLC_column
BiopharmaceuticalBiopharmaceutical
The filing pathway requires more testing than for small-molecule generics, but less testing than for registering completely new ... They (or their precursors or components) are isolated from living sources-human, animal, plant, fungal, or microbial. They can ... Due to their heterogeneity and the high process sensitivity, originators and follow-on biosimilars will exhibit variability in ... in addition to physicochemical testing, biological testing for full characterisation. The characterisation of a biological ...
https://en.wikipedia.org/wiki/Biopharmaceutical
Empiric therapyEmpiric therapy
... likelihood for a certain microbial etiology and pre-test probability for antimicrobial resistance prior to therapy, risk of bad ... There is a chance the causal bacteria, or its sensitivity to antibiotics, may be different to community-acquired pneumonia. ... In this case, there may be little if any perceived benefit of using what may be costly and inconclusive tests that will only ... of indicating antibiotics empirically exists where a causative pathogen is likely albeit unknown and where diagnostic tests ...
https://en.wikipedia.org/wiki/Empiric_therapy
OxycodoneOxycodone
Deng Z, Liu T (2015). "Faculty Opinions recommendation of A microbial biomanufacturing platform for natural and semisynthetic ... Most common side effects of oxycodone include reduced sensitivity to pain, delayed gastric emptying, euphoria, anxiolysis, ... Many commercial opiate screening tests cross-react appreciably with oxycodone and its metabolites, but chromatographic ... Thodey K, Galanie S, Smolke CD (October 2014). "A microbial biomanufacturing platform for natural and semisynthetic opioids". ...
https://en.wikipedia.org/wiki/Oxycodone
BioluminescenceBioluminescence
"Philips launches 'Microbial Home' new forward looking design concepts". Retrieved 8 May 2017.[permanent dead link] Cha, Bonnie ... It proves to be a very good biosensor to test cell viability. Optical biosensors include process of measurement of luminescence ... Chris Riley, "Glowing plants reveal touch sensitivity", BBC 17 May 2000. Halverson, Nic (15 August 2013). "Bacteria-Powered ... In 2011, Philips launched a microbial system for ambience lighting in the home. An iGEM team from Cambridge (England) has ...
https://en.wikipedia.org/wiki/Bioluminescence
Environmental DNAEnvironmental DNA
Sensitivity is how likely the DNA marker will be present in the sampled water, and can be increased simply by taking more ... Orcutt, B. N.; Sylvan, J. B.; Knab, N. J.; Edwards, K. J. (2011). "Microbial Ecology of the Dark Ocean above, at, and below the ... This transport could take between 3 to 12 days depending on the size and morphology of test. However, it remains unclear how ... This method is effective as pH of the water does not affect the DNA as much as previously thought, and sensitivity can be ...
https://en.wikipedia.org/wiki/Environmental_DNA
Function-spacer-lipid Kode constructFunction-spacer-lipid Kode construct
High biovisibility - as the spacer holds the F moiety away for the membrane it is able to achieve increased sensitivity, ... These additional sequences may include unwanted microbial related sequences (as determined by a BLAST analysis) that can cause ... Chesla, S; Henry, S; Eatz, R; Sinor, L (2010). "Solid phase syphilis test utilizing KODE technology". Transfusion. 50: 196A- ... Consequently, the constructs are compatible in vivo use, and can improve diagnostic assay sensitivity by allowing for the use ...
https://en.wikipedia.org/wiki/Function-spacer-lipid_Kode_construct
MultiomicsMultiomics
... combining data collected by targeted tests ... and global assays (such as genome sequencing) with other patient-specific ... "Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases". Nature. 569 (7758): 655-662. Bibcode:2019Natur.569 ... "Homogenous 96-Plex PEA Immunoassay Exhibiting High Sensitivity, Specificity, and Excellent Scalability". PLOS ONE. 9 (4): ...
https://en.wikipedia.org/wiki/Multiomics
Viking lander biological experimentsViking lander biological experiments
The landers each used a robotic arm to pick up and place soil samples into sealed test containers on the craft. The two landers ... The first successful Mars landers, Viking 1 and Viking 2, then carried out experiments to look for biosignatures of microbial ... In 2006, scientist Rafael Navarro demonstrated that the Viking biological experiments likely lacked sensitivity to detect trace ... Sterilization control tests were subsequently carried out by heating various soil samples. Samples heated for 3 hours at 160 °C ...
https://en.wikipedia.org/wiki/Viking_lander_biological_experiments
Akkermansia muciniphilaAkkermansia muciniphila
It also maintains microbial balance by competing with and inhibiting the over growth of other mucin degrading bacteria. A. ... Then in 2019, the same team of Belgian researchers from the UCLouvain tested for the first time in humans the impact of an oral ... A study published in June 2015 showed a positive association between increased A. muciniphila abundance, insulin sensitivity, ... Microbial Pathogenesis. 106: 171-181. doi:10.1016/j.micpath.2016.02.005. hdl:10138/236401. PMID 26875998. Luo, Yuheng; Lan, ...
https://en.wikipedia.org/wiki/Akkermansia_muciniphila
MetforminMetformin
"Laboratory Tests - Metformin". U.S. Food and Drug Administration (FDA). 5 June 2020. Retrieved 5 June 2020. This article ... Metformin also induces a profound shift in the faecal microbial community profile in diabetic mice, and this may contribute to ... It works by decreasing glucose production in the liver, by increasing the insulin sensitivity of body tissues, and by ... "Laboratory Tests - Metformin". U.S. Food and Drug Administration (FDA). 3 February 2020. Retrieved 4 February 2020. "FDA ...
https://en.wikipedia.org/wiki/Metformin
Potential applications of graphenePotential applications of graphene
2014). Sensitivity and Offset Voltage Testing in the Hall-Effect Sensors Made of Graphene. Advances in Intelligent Systems and ... molecularly gateable structure make antibody-functionalized graphene sheets excellent candidates for mammalian and microbial ... In laboratory tests, the leading edge of a helicopter rotor blade was coated with the composite, covered by a protective metal ... In testing, the researchers charged and discharged the devices for thousands of cycles with almost no loss of capacitance. The ...
https://en.wikipedia.org/wiki/Potential_applications_of_graphene
SourdoughSourdough
Refreshment intervals of longer than three days acidify the dough and may change the microbial ecosystem. The intervals between ... C. milleri and C. holmii are physiologically similar, but DNA testing established them as distinct. Other yeasts reported found ... Sourdough fermentation reduces wheat components that may contribute to non-celiac wheat sensitivity and irritable bowel ... Micro-Organisms in Foods 6 Microbial Ecology of Food Commodities. New York: Kluwer Academic/Plenum Publishers. 2005. pp. 409- ...
https://en.wikipedia.org/wiki/Sourdough
InfluenzaInfluenza
Nucleic acid-based tests (NATs) amplify and detect viral nucleic acid. Most of these tests take a few hours, but rapid ... Initially, the microbial agent responsible for influenza was incorrently identified in 1892 by R. F. J. Pfeiffer as the ... For example, NATs have high sensitivity and specificity but are impractical in under-resourced regions due to their high cost, ... Rapid influenza diagnostic tests (RIDTs) are a simple way of obtaining assay results, are low cost, and produce results quickly ...
https://en.wikipedia.org/wiki/Influenza
Marine protistsMarine protists
... as well as generating hypotheses on microbial interactions based on correlations of estimated microbial abundances over ... Shelled and naked amoeba Naked amoeba showing food vacuoles and ingested diatom Shell or test of a testate amoeba, Arcella sp. ... Gafar, N.A., Eyre, B.D. and Schulz, K.G. (2019) "A comparison of species specific sensitivities to changing light and carbonate ... Giant kelp, a brown algae, is not a true plant, yet it is multicellular and can grow to 50m Interaction between microbial ...
https://en.wikipedia.org/wiki/Marine_protists
Root canal treatmentRoot canal treatment
... and the use of diagnostic tests. There are several diagnostic tests that can aid in the diagnosis of the dental pulp and the ... "sensitivity" in the area. Other studies have found that endodontic therapy patients report the maximum pain the day following ... is intended to result in the elimination of infection and the protection of the decontaminated tooth from future microbial ... Radiographs Dental pulp tests If a tooth is considered so threatened (because of decay, cracking, etc.) that future infection ...
https://en.wikipedia.org/wiki/Root_canal_treatment
List of skin conditionsList of skin conditions
Hanke, William (30 August 2010). "Dermatology In-Review Study Guide" (PDF). Educational Testing and Assessment Systems. ... lacquer sensitivity) Lanolin-induced Lipstick-induced Local anesthetic-induced Makassar ebony dermatitis Marine plant-induced ... microbial eczema, nummular eczema, nummular neurodermatitis) Nutritional deficiency eczema Sulzberger-Garbe syndrome (oid-oid ...
https://en.wikipedia.org/wiki/List_of_skin_conditions
AllergyAllergy
Some patients may believe they have determined their own allergic sensitivity from observation, but a skin test has been shown ... and thus normally benign microbial objects-like pollen-will trigger an immune response. The hygiene hypothesis was developed to ... Skin testing is also known as "puncture testing" and "prick testing" due to the series of tiny punctures or pricks made into ... Allergy blood tests are very safe since the person is not exposed to any allergens during the testing procedure. The test ...
https://en.wikipedia.org/wiki/Allergy
Protein detectionProtein detection
The current abstraction technique can control protein degradation through the microbial proteolytic enzymes. The microbial ... But it can not test protein in soybean existing in brewed soybean products. There are different studies to conduct experiments ... The enzyme-linked immunosorbent assay (ELISA) can be used as the technique to detect walnuts residues with great sensitivity ... The microbial proteolytic enzymes possibly restrain the detection of soybean protein storing in the brewed soybean products. ...
https://en.wikipedia.org/wiki/Protein_detection
Pesticide resistancePesticide resistance
EPPO's efficacy testing site: "EPPO database on PP1 Standards". EPPO (European and Mediterranean Plant Protection Organization ... Alternatively, the number and/or sensitivity of biochemical receptors that bind to the pesticide may be reduced. Behavioral ... or microbial degradation of the pesticide. The United Nations' World Health Organization established the Worldwide Insecticide ... a heritable change in the sensitivity of a pest population that is reflected in the repeated failure of a product to achieve ...
https://en.wikipedia.org/wiki/Pesticide_resistance
Third-generation sequencingThird-generation sequencing
... the study reported an exon detection sensitivity averaging to 69% and transcript detection sensitivity had an average of a mere ... A straightforward Mann-Whitney U test can detect modified portions of the E. coli sequence, as well as further split the ... For example, in one study, it was demonstrated that de novo assembly of a microbial genome using PacBio sequencing alone ... This approach has been previously tested and reported to reduce the error rate by more than 3 folds. Metagenomics is the ...
https://en.wikipedia.org/wiki/Third-generation_sequencing
SoybeanSoybean
... and the diagnosis of soy allergy is often based on symptoms reported by parents and results of skin tests or blood tests for ... The most common cause of this unusual disorder is a sensitivity to cow's milk, but soy formulas can also be the trigger. The ... The major product of daidzein microbial metabolism is equol. Only 33% of Western Europeans have a microbiome that produces ... An allergy test that is positive demonstrates that the immune system has formed IgE antibodies to soy proteins. However, this ...
https://en.wikipedia.org/wiki/Soybean
Campylobacter fetusCampylobacter fetus
Agglutination is primarily used when the sample is obtained from a vaginal mucous wash, and the test may reach a sensitivity of ... Veterinary Microbiology and Microbial Disease. John Wiley & Sons. ISBN 978-1-118-25116-4. Parkinson, Timothy J. (2019). " ... multiple samples are to be collected from each animal and multiple tests may be used simultaneously to increase sensitivity and ... Once cultured, molecular tests can be performed to obtain a more accurate diagnosis. Measuring IgA antibodies in vaginal mucus ...
https://en.wikipedia.org/wiki/Campylobacter_fetus
Trace Gas OrbiterTrace Gas Orbiter
This may indicate the presence of microbial life on Mars, or a geochemical process such as volcanism or hydrothermal activity. ... The Trace Gas Orbiter and descent module Schiaparelli completed testing and were integrated to a Proton rocket at the Baikonur ... The orbiter has very high sensitivity to (at least) the following molecules and their isotopomers: water (H2O), hydroperoxyl ( ... Gibney, Elizabeth (11 March 2016). "Mars launch to test collaboration between Europe and Russia". Nature. 531 (7594): 288-299. ...
https://en.wikipedia.org/wiki/Trace_Gas_Orbiter
Polymerase chain reactionPolymerase chain reaction
Prospective parents can be tested for being genetic carriers, or their children might be tested for actually being affected by ... The high sensitivity of PCR permits virus detection soon after infection and even before the onset of disease. Such early ... PCR Detection of Microbial Pathogens. Methods in Molecular Biology. Vol. 216. Totowa, New Jersey: Humana Press. pp. 3-29. doi: ... there is even a proposal to replace the traditional antibody-based tests for blood type with PCR-based tests. Many forms of ...
https://en.wikipedia.org/wiki/Polymerase_chain_reaction
Ancient proteinAncient protein
This pressured various groups of anaerobic prokaryotes, changing the microbial diversity and global metabolome, as well as ... yielded none of the previous findings despite extensive testing, and only the presence of protein breakdown products were ... these techniques also increase the sensitivities to contamination. Zooarcheology uses mass spectrometry and protein analyses to ...
https://en.wikipedia.org/wiki/Ancient_protein
Digital microfluidicsDigital microfluidics
In one application, microbial cultures have been transferred onto the chip and allowed to grow with the use of sterile ... In one example the use of a custom DMF system for urine drug testing enabled the creation of an instrument weighing only 25 kg ... A potential issue that arises through the use of NMR is low mass sensitivity, however this can be corrected for by employing ... To validate that this was a viable space for microbial growth, a transformation assay was carried out in the device. This ...
https://en.wikipedia.org/wiki/Digital_microfluidics
Neural codingNeural coding
The main drawback of such a coding scheme is its sensitivity to intrinsic neuronal fluctuations. In the primary visual cortex ... "Informational lesions: optical perturbations of spike timing and neural synchrony via microbial opsin gene fusions." Cambridge ... and thereby can test whether or not temporal coding occurs in specific neural circuits. Optogenetic technology also has the ...
https://en.wikipedia.org/wiki/Neural_coding
Loop-mediated isothermal amplificationLoop-mediated isothermal amplification
With its simplicity, researchers are able to test one or more samples with little hands on time which is helping cut down the ... ASTMH 2015 , Molecular detection of Plasmodium with Loop Mediated Isothermal Amplification (LAMP) and sensitivity comparison to ... J Microbial Methods. 132: 41-45. doi:10.1016/j.mimet.2016.10.020. PMID 27984058. Habibzadeh, Parham; Mofatteh, Mohammad; Silawi ... Walker, Peter (21 May 2020). "UK coronavirus test with 20-minute wait being trialled". The Guardian. Park, Gun-Soo; Ku, Keunbon ...
https://en.wikipedia.org/wiki/Loop-mediated_isothermal_amplification
Browsing by Subject Microbial Sensitivity TestsBrowsing by Subject "Microbial Sensitivity Tests"
Standardization of methods for conducting microbic sensitivity tests : second report of the Expert Committee on Antibiotics [‎ ... Requirements for antimicrobic susceptibility tests : 1. AGAR diffusion tests using antimicrobic susceptibility discs, ... In vitro micro-test (‎Mark III)‎ for the assessment of the response of Plasmodium falciparum to chloroquine, mefloquine, ... Accuracy of the VITEK 2 system for a rapid and direct identification and susceptibility testing of Gram-negative rods and Gram- ...
https://extranet.who.int/iris/restricted/browse?authority=Microbial+Sensitivity+Tests&type=mesh
Results of search for 'su:{Microbial sensitivity tests}' › WHO HQ Library catalog
Results of search for su:{Microbial sensitivity tests} Refine your search. *. Availability. * Limit to currently available ... Standardization of methods for conducting microbic sensitivity tests : second report of the Expert Committee on Antibiotics [ ... Field application of in vitro assays for the sensitivity of human malaria parasites to antimalarial drugs / Léonardo K. Basco. ... A rapid method for isolation cultivation and testing drug susceptiblity of M. tuberculosis / N. Veeraraghavan. by Veeraraghavan ...
https://kohahq.searo.who.int/cgi-bin/koha/opac-search.pl?q=su:%7BMicrobial%20sensitivity%20tests%7D
Browsing by Subject
Microbial Collagenase [‎1]‎. Microbial Interactions [‎2]‎. Microbial Sensitivity Tests [‎22]‎. Microbiological Phenomena [‎2]‎ ...
https://apps.who.int:80/iris/browse?rpp=20&offset=3774&etal=-1&sort_by=-1&type=mesh&starts_with_previous=K&order=ASC
Uncovering the Hidden Antibiotic Potential of CannabisUncovering the Hidden Antibiotic Potential of Cannabis
Microbial Sensitivity Tests * Polymyxin B / pharmacology * Staphylococcal Infections / blood * Staphylococcal Infections / drug ...
https://pubmed.ncbi.nlm.nih.gov/32017534/
Advanced Search Results - Public Health Image Library(PHIL)Advanced Search Results - Public Health Image Library(PHIL)
Categories: Microbial Sensitivity Tests Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...
https://phil.cdc.gov/AdvancedSearchResults.aspx?Search=Microbial+Sensitivity+Tests&parentid=16786&catid=16783
Chronic Sinusitis Medication: Penicillins, Cephalosporins, Macrolides, Fluoroquinolones, Tetracyclines, Anti-Infectives,...Chronic Sinusitis Medication: Penicillins, Cephalosporins, Macrolides, Fluoroquinolones, Tetracyclines, Anti-Infectives,...
Ideally, direct antibiotics against the organism obtained from endoscopic sampling and based on microbial sensitivity testing. ... Clinical implications of microbial biofilms in chronic rhinosinusitis and orbital cellulitis. BMC Ophthalmol. 2016 Sep 21. 16 ( ...
https://www.medscape.com/answers/232791-52548/which-medications-in-the-drug-class-corticosteroids-are-used-in-the-treatment-of-chronic-sinusitis
NIOSHTIC-2 Search Results - Full View
Sensitivity-testing; Aerosol-particles; Aerosol-sampling; Genes; Genetic-engineering; Cell-growth; Cellular-reactions; Samplers ... Sample-preparation; Microbial-test-systems; Microscopic-analysis; Disease-transmission; Cell-cultures; Quantitative-analysis; ... To increase the sensitivity for detecting infectious influenza virus in an aerosol sample, the viral replication assay was ... Current screening methodologies for detecting infectious airborne influenza virus are limited and lack sensitivity. ...
http://www2a.cdc.gov/nioshtic-2/BuildQyr.asp?s1=lindsley&f1=%2A&Startyear=&Adv=0&terms=1&EndYear=&Limit=10000&sort=&D1=10&PageNo=7&RecNo=65&View=f&
Opportunistic Pulmonary Bordetella hinzii Infection after Avian Exposure - Volume 21, Number 12-December 2015 - Emerging...
data). MIC testing should be performed to confirm the sensitivity of any such isolates. We can speculate about possible ... Further clinical and microbial investigations are necessary to understand the epidemiology and the pathogenicity of B. hinzii. ... The interpretation of antimicrobial sensitivity testing is not established and is usually done by inference from other ... According to in vitro sensitivity testing for human isolates described in the literature and pharmacology, piperacillin/ ...
https://wwwnc.cdc.gov/eid/article/21/12/15-0400
School of Medicine, Dentistry and Biomedical Sciences - Research output - Queen's University Belfast
Microbial Sensitivity Tests 27% * Poster presentation: The role of neck strength in mitigating sport related concussion: a ... 272 Point-of-care testing in paediatric settings in the UK and Ireland: a cross-sectional study. Pandey, M., Lyttle, M., Cathie ...
https://pure.qub.ac.uk/en/organisations/school-of-medicine-dentistry-and-biomedical-sciences/publications/?type=%2Fdk%2Fatira%2Fpure%2Fresearchoutput%2Fresearchoutputtypes%2Fcontributiontojournal%2Fabstract
FARMACIA Y BIOQUIMICA - Research output - San Luis Gonzaga National University of Ica
Agricultural Biotechnologies: Conference 11Agricultural Biotechnologies: Conference 11
... enhance the speed and sensitivity of microbial testing and are increasingly being applied in developing countries. ... sensitivity and speed of microbial testing. Molecular typing methodologies, commonly involving the polymerase chain reaction ( ... Microbial cultures can be genetically improved using both traditional and molecular approaches, and improvement of bacteria, ... 2.4 Biotechnology in diagnostics for food testing Many of the classical food microbiological methods used in the past were ...
https://www.fao.org/biotech/biotech-forum/conference-11/en/
Relationship Between Vancomycin Trough Concentrations and Nephrotoxici by John A. Bosso, Jean Nappi et al."Relationship Between Vancomycin Trough Concentrations and Nephrotoxici" by John A. Bosso, Jean Nappi et al.
Microbial Sensitivity Tests; Middle Aged; Multivariate Analysis; Prospective Studies; South Carolina (epidemiology); ...
https://scholarcommons.sc.edu/phar_facpub/40/
Frontiers | Methane Emission in a Specific Riparian-Zone Sediment Decreased with Bioelectrochemical Manipulation and...Frontiers | Methane Emission in a Specific Riparian-Zone Sediment Decreased with Bioelectrochemical Manipulation and...
... that govern microbial competition and coexistence in anaerobic soils and sediments, because subsurface microbial processes can ... We did not find a direct link between bioelectrochemical treatment and microbial community membership; however, we did find a ... because subsurface microbial processes can effect greenhouse gas emissions from soils, possibly resulting in impacts at the ... and we harvested biofilms from the electrodes to quantify microbial community dynamics. At the upstream site, which had a lower ...
https://www.frontiersin.org/articles/10.3389/fmicb.2015.01523/full
Activity of 5-chloro-pyrazinamide in mice infected with Mycobacterium tuberculosis or Mycobacterium bovis - Fingerprint -...Activity of 5-chloro-pyrazinamide in mice infected with Mycobacterium tuberculosis or Mycobacterium bovis - Fingerprint -...
Microbial Sensitivity Tests 19% * Serum 8% * Isoniazid 7% * Aerosols 6% * Punctures 6% ...
https://experts.umn.edu/en/publications/activity-of-5-chloro-pyrazinamide-in-mice-infected-with-mycobacte/fingerprints/
Provenge (Sipuleucel-T Suspension for Intravenous Infusion): Uses, Dosage, Side Effects, Interactions, WarningProvenge (Sipuleucel-T Suspension for Intravenous Infusion): Uses, Dosage, Side Effects, Interactions, Warning
Product Safety Testing. PROVENGE is released for infusion based on the microbial and sterility results from several tests: ... Dendreon will attempt to identify the microorganism, perform antibiotic sensitivity testing on recovered microorganisms, and ... In-process and final sterility tests are initiated prior to shipping, but the final results are not available for up to 7 days ... PROVENGE is not tested for transmissible infectious diseases. Therefore, patient leukapheresis material and PROVENGE may carry ...
https://www.rxlist.com/provenge-drug.htm
Bournemouth University Research Online [BURO] - Marine-derived quorum-sensing inhibitory activities enhance the antibacterial...Bournemouth University Research Online [BURO] - Marine-derived quorum-sensing inhibitory activities enhance the antibacterial...
Anti-Bacterial Agents ; Biofilms ; Chromobacterium ; Microbial Sensitivity Tests ; Pseudoalteromonas ; Pseudomonas aeruginosa ... was observed over the concentration range tested (MBC , 16 mg/mL). Sub-MIC concentrations (1 mg/mL) of KS8 crude organic ...
http://eprints.bournemouth.ac.uk/24479/
Synthesis and antimicrobial evaluation of new nitric oxide-donating fluoroquinolone/oxime hybrids<...
Microbial Sensitivity Tests Medicine & Life Sciences 38% View full fingerprint Cite this. * APA ...
https://jhu.pure.elsevier.com/en/publications/synthesis-and-antimicrobial-evaluation-of-new-nitric-oxide-donati
Publications | - CCMARPublications | - CCMAR
Filters: Keyword is Microbial Sensitivity Tests [Clear All Filters]. 2015. Castro J. Using an in-vitro biofilm model to assess ...
https://ccmar.ualg.pt/en/biblio2?f%5Bkeyword%5D=1061
Immunologic Tests for Infectious Disease - Infectious Diseases - Merck Manuals Professional EditionImmunologic Tests for Infectious Disease - Infectious Diseases - Merck Manuals Professional Edition
Immunologic Tests for Infectious Disease - Explore from the Merck Manuals - Medical Professional Version. ... Test sensitivities, although usually high, can vary, sometimes according to patient age, microbial serotype, specimen type, or ... Western blot test The Western blot test detects antimicrobial antibodies in the patients sample (eg, serum, other body fluid) ... The Western blot typically has good sensitivity, although often less than that of screening tests such as ELISA, but generally ...
https://www.merckmanuals.com/en-ca/professional/infectious-diseases/laboratory-diagnosis-of-infectious-disease/immunologic-tests-for-infectious-disease
A Novel Bioerodible Deep Scleral Lamellar Cyclosporine Implant for Uveitis | EmmesA Novel Bioerodible Deep Scleral Lamellar Cyclosporine Implant for Uveitis | Emmes
Microbial Sensitivity Tests; Panuveitis; Permeability; Recurrence; Sclera ...
https://emmes.com/publications/842
Search ResultsSearch Results
Complete ciprofloxacin resistance in gonococcal isolates in an urban Ugandan clinic: findings from a cross-sectional study.
Microbial Sensitivity Tests, Drug Resistance, Bacterial, Uganda, Female, Male ... Antimicrobial susceptibility testing was performed using disk diffusion and isolates were sent to a reference laboratory for ... AMR testing of N. gonorrhoeae isolates is needed to ensure optimal treatment and prevention of antibiotic resistance ... and to describe methodological challenges to carrying out AMR testing. The study was conducted at an HIV outpatient service for ...
https://www.repository.cam.ac.uk/handle/1810/287170
Reliability of microbial sampling in assuring food safety and calculation of prevalence following negative testsReliability of microbial sampling in assuring food safety and calculation of prevalence following negative tests
Microbial testing is still important but it is critical to understand its limitations in assuring food safety. ... Zwietering, M.H. and den Besten, H.M.W. (2016). Microbial testing in food safety: effect of specificity and sensitivity on ... Microbial testing is still important but it is critical to understand its limitations in assuring food safety.. Despite the ... Reliability of microbial sampling in assuring food safety and calculation of prevalence following negative tests ...
https://www.dairyscience.info/index.php/food-model/275-sampling.html
Pesquisa | Portal Regional da BVSPesquisa | Portal Regional da BVS
... as well as the use of antimicrobials without culture examination and sensitivity test. In this sense, it is concluded that it ... With the advance of medicine and the increase in the use of antimicrobials, microbial resistance has become a serious problem ... Ultimately, the library can serve both as the seed and as the test bed to create a machine-searchable virtual library of linked ... The indiscriminate use of antimicrobials is the main factor of microbial resistance, ...
https://pesquisa.bvsalud.org/portal/?lang=pt&q=mh:%22Bibliotecas%20Digitais%22
BF Parasit Dis F
Yes; better... though best would be to do a rudimentary sensitivity test/run... ,. I have a seeded identical QT and could treat ... microbial issues starting w/ other causes... mostly environmental, social, nutritional... and cured by fixing the same. Moving ... My water has been tested on average twice a week and I have just bought my own water test kit. My test last night showed a pH ... Not w/o testing for free copper daily,. and your good to go (if no signs of spots or symptoms), but do you think this is long ...
https://www.wetwebmedia.com/BFParasitDisF.htm
MESH TREE NUMBER CHANGES - 2012 MeSH. August 19, 2011MESH TREE NUMBER CHANGES - 2012 MeSH. August 19, 2011
D2.33.755.624.698.573 Microbial Sensitivity Tests E1.370.225.875.595 Microbiological Techniques E1.370.225.875 Microdissection ... E5.200.932.600 Parasitic Sensitivity Tests E1.370.225.940 Partial Thromboplastin Time E1.450.375.115.600 E1.370.225.625.115.600 ... G5.355.760.615.750 Skin Irritancy Tests E5.940.74.500 E5.940.790.500 Skin Test End-Point Titration E1.370.750.300.750 E1.370. ... C16.131.666.34.500 Acute Toxicity Tests E5.940.74 E5.940.790 (Replaced for 2012 by Toxicity Tests, Acute) Adenine Nucleotide ...
https://decs.bvs.br/P/mnchg2012.txt
Susceptibility rates of clinically important bacteria collected from intensive care units against colistin, carbapenems, and...
Microbial Sensitivity Tests 41% * Bacillus 38% * Enterobacteriaceae 28% * Pseudomonas aeruginosa 24% * Morganella morganii 20% ...
https://tmu.pure.elsevier.com/zh/publications/susceptibility-rates-of-clinically-important-bacteria-collected-f/fingerprints/
BacteriaInfectionsBacterialDrug ResistanceBiofilmsAntibioticsStrainsChanges in microbialBiochemicalSusceptibilityTuberculosisSpecificityAssayIsolatesContaminationAntibiotic sensitivitySerumGenomicsBioassaysEfficacyConcentrationsSkin sensitivityEnzymesNitrogenPermeabilityOrganismsInfectionBiogeochemicalAntibodySoilsFungusEnzymeAntigenLogistic regressionMetabolismSwabPathogensResultsScreeningAllergyMicrobiological2020DiffusionCulturePharmaceuticalSpecimen
Bacteria13
  • In agglutination tests (eg, latex agglutination, coaggregation), very small particles (latex beads, gelatin particles, bacteria) are coupled to a reagent antigen or antibody. (merckmanuals.com)
  • Furthermore, the essential oil exhibited antibacterial activity (MIC, more than 800 microg/mL versus 0.125 microg/mL for ampicillin) after it was tested against 6 Gram(+) bacteria and 8 Gram(-) bacteria. (unboundmedicine.com)
  • Develop methods for in vitro antimicrobial sensitivity testing and phenotypic and genotypic characteristics of bacteria. (fda.gov)
  • The global iron-related changes, confirmed by modulation of activity of the transcription factor Fur, may underlie enhanced siderophore excretion, diminished intracellular iron pools, and the sensitivity of CO-challenged bacteria to metal chelators. (essex.ac.uk)
  • Ear cytology - Swabbing your pet's ear to identify whether the infection was incited by a microbial infection due to bacteria or fungus. (vetericyn.com)
  • Culture or sensitivity testing - Creating an ear culture to determine the specific strain of bacteria responsible for the infection, and which antibiotics will be able to combat them. (vetericyn.com)
  • IMSEAR at SEARO: Antibiotic sensitivity pattern of the bacteria isolated from nosocomial infections in ICU. (who.int)
  • Singh AK, Sen MR, Anupurba S, Bhattacharya P. Antibiotic sensitivity pattern of the bacteria isolated from nosocomial infections in ICU. (who.int)
  • Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses). (bvsalud.org)
  • The identification of bacteria to species level was done using conventional biochemical identification tests scheme. (bvsalud.org)
  • The common microbial aetiology of postoperative inguinal hernia wound infection is Gram-positive bacteria. (bvsalud.org)
  • Seokheun "Sean" Choi, assistant professor of computer and electrical engineering at Binghamton University, along with two of his students, developed the device, a microbial fuel cell that runs on the bacteria available in a few drops of dirty water. (labmanager.com)
  • The short-term microbial toxicity tests involve bacteria, algae, protozoa and fungi (yeasts). (biomedcentral.com)
Infections8
  • Blood test - In some cases, ear infections are the result of a more pervasive underlying condition. (vetericyn.com)
  • The symptoms above could be caused by gluten or they cold be caused by another food sensitivity, gut infections, stress, low digestive enzymes or a number of other reasons. (planetnaturopath.com)
  • A fungal culture test helps diagnose fungal infections . (medlineplus.gov)
  • Both superficial and systemic fungal infections can be diagnosed with a fungal culture test. (medlineplus.gov)
  • Blood tests are often used to diagnose more serious fungal infections. (medlineplus.gov)
  • Antimicrobial resistance is currently a very big global problem, initially reported in human patients but it has spread to the animal population, making it a very serious risk due to rampart difficult to treat microbial infections. (mak.ac.ug)
  • In this work, we attempted to decipher the interplay between resistance profiles, high-risk clones, and virulence, testing a large (n = 140) collection of well-characterized P. aeruginosa isolates from different sources (bloodstream infections, nosocomial outbreaks, cystic fibrosis, and the environment) in a Caenorhabditis elegans infection model. (repositoriosaludmadrid.es)
  • This undermines the effectiveness of the available treatment options and thus contributes to the persistence of microbial infections. (who.int)
Bacterial2
  • Specimen handling varies, but if testing is to be delayed, the specimen should typically be refrigerated or frozen to prevent overgrowth of bacterial contaminants. (merckmanuals.com)
  • Only one bacterial isolate exhibited sensitivity to all the 20 test phages, which indicated low efficacy. (mak.ac.ug)
Drug Resistance1
  • Forty-six isolates (88.5%) were resistant to at least three classes of drugs (multi drug resistance) and these were tested for sensitivity to 20 stock bacteriophages. (mak.ac.ug)
Biofilms3
  • At two sites within the same stream riparian zone during the course of 6 weeks in the spring of 2013, we measured CH 4 and N 2 /N 2 O emissions from soil chambers containing either poised or unpoised electrodes, and we harvested biofilms from the electrodes to quantify microbial community dynamics. (frontiersin.org)
  • In addition, analyses performed on biofilms via confocal microscopy revealed that VLL-28 is differentially active on all the strains tested, with C. albicans and C. parapsilosis being the most sensitive ones. (univr.it)
  • Polymeric wound dressings which play an active role in wound healing by keeping the wound environment moist and preventing the formation of microbial biofilms, could be in alginate, hydrogel or hydrocolloid structure, film or foam form. (fabad.org.tr)
Antibiotics1
  • Use of antibiotics should be gradual and based on proper culture and sensitivity tests so that such resistant strains do not develop in future," a senior surgeon from Hinduja hospital told PTI. (indiatvnews.com)
Strains2
  • Certain microorganisms associated with fermented foods, in particular strains of the Lactobacillus species, are probiotic i.e. used as live microbial dietary supplements or food ingredients that have a beneficial effect on the host by influencing the composition and/or metabolic activity of the flora of the gastrointestinal tract. (fao.org)
  • Suspected Staphylococcus isolates were identified initially using standard biochemical tests, then strains that were confirmed by polymerase chain reaction [‎29 S, aureus and 17 S. saprophyticus]‎ were evaluated for their susceptibility to different antimicrobials. (who.int)
Changes in microbial2
  • While neutral effects such as drift, dispersal, and speciation influence microbial communities, selective pressures are the biogeochemical determinants that drive changes in microbial community composition based on variations in the relative fitness of microbial sub-populations [ 2 ]. (nature.com)
  • The land-use intensity, season, and geographic location were the main drivers of changes in microbial C-dynamics. (essopenarchive.org)
Biochemical3
  • During fermentation processes, microbial growth and metabolism (the biochemical processes whereby complex substances and food are broken down into simple substances) result in the production of a diversity of metabolites (products of the metabolism of these complex substances). (fao.org)
  • in addition to standard biochemical tests. (mak.ac.ug)
  • Samples were inoculated into bacteriological media and were identified by biochemical characterization followed by antimicrobial susceptibility tests. (researchsquare.com)
Susceptibility2
  • Studies on resistance to chloroquine by Plasmodium falciparum with potential application to the development of a modified in vitro susceptibility test / by Michael Davis Rogers. (who.int)
  • Antimicrobial susceptibility testing was performed using disk diffusion and isolates were sent to a reference laboratory for agar dilution direct susceptibility testing. (cam.ac.uk)
Tuberculosis1
  • A rapid method for isolation cultivation and testing drug susceptiblity of M. tuberculosis / N. Veeraraghavan. (who.int)
Specificity4
  • The ease of use, sensitivity, specificity, cost effectiveness and reduced preparation and running time all contribute to its prevalence over traditional or culture-based methods. (europeanpharmaceuticalreview.com)
  • 13 Some of these techniques, like Resistome Capture, ResCap, can assist with identifying antimicrobial genes with very low specificity and sensitivity. (europeanpharmaceuticalreview.com)
  • It is a fully automated, rapid, molecular diagnostic system which utilizes the power of real-time or quantitative Polymerase Chain Reaction (qPCR), considered the gold standard in the field, and known for its high sensitivity and specificity. (lexagene.com)
  • They have tested many hundreds of kits to establish the sensitivity and specificity of the tests to help evaluate the utility of a national testing programme. (me.uk)
Assay3
  • To increase the sensitivity for detecting infectious influenza virus in an aerosol sample, the viral replication assay was developed. (cdc.gov)
  • We used a lateral flow assay and ELISA to test serum samples from COVID-19 cases, confirmed by polymerase chain reaction assays (study group) and pre-pandemic stored serum samples (control group). (who.int)
  • Lateral flow assay and ELISA techniques gave consistent results for IgG/IgM antibody measurements towards spike and nucleocapsid proteins, suggesting that both methods can be used to detect COVID-19 where access to molecular test kits is difficult. (who.int)
Isolates7
  • The objectives of the study were to determine the AMR patterns of Neisseria gonorrhoeae clinical isolates to antimicrobial agents in patients with HIV or high risk of HIV acquisition, to compare the concordance of disk diffusion and agar dilution as methods for determining AMR to N. gonorrhoeae, and to describe methodological challenges to carrying out AMR testing. (cam.ac.uk)
  • AMR testing of N. gonorrhoeae isolates is needed to ensure optimal treatment and prevention of antibiotic resistance progression. (cam.ac.uk)
  • This study is an attempt to know the antibiotic sensitivity pattern of the common isolates in ICU. (who.int)
  • Daptomycin has been shown to improve clinical outcomes in patients with BSIs caused by MRSA isolates with vancomycin MICs of >1 mg/liter, but these studies relied on automated testing systems. (henryford.com)
  • Antibiotic sensitivity was performed on isolates using the modified Bauer Kirby disk diffusion test on plain Mueller Hinton (MH) agar and MH agar with 5% horse blood . (bvsalud.org)
  • Confirmatory tests including carbohydrate utilization were performed on isolates to determine species. (who.int)
  • Furthermore, our general high-throughput approach can be applied to other environments, isolates, and conditions to systematically help identify selective pressures on microbial communities. (nature.com)
Contamination4
  • Remove mold in Room 18 a nd women's damage and microbial contamination. (cdc.gov)
  • A container that loses, or does not have, good closure integrity is at risk for microbial contamination. (pharmtech.com)
  • Routine microbial contaminant testing during bioprocessing is imperative to maintain control over product yield, quality, safety, efficacy, and to correctly identify any microbial contamination (Figure 2). (lexagene.com)
  • Mycoplasma species, specifically Mycoplasma arginini, Mycoplasma orale, Mycoplasma hyorhinis, and Mycoplasma fermentans, as well as a close relative Acholeplasma laidlawii, are all a major concern for microbial contamination in bioprocessing.6 A mycoplasma test was designed to detect all the above mentioned five species of mycoplasmas. (lexagene.com)
Antibiotic sensitivity1
  • Antibiotic sensitivity test was done according to Kirby Bauer method. (who.int)
Serum3
  • The Western blot test detects antimicrobial antibodies in the patient's sample (eg, serum, other body fluid) by their reaction with target antigens (eg, viral components) that have been immobilized onto a membrane by blotting. (merckmanuals.com)
  • The determination of serum urea nitrogen is the most widely used test for the evaluation of kidney function. (cdc.gov)
  • The test is frequently requested in conjunction with the serum Creatinine test for the differential diagnosis of prerenal, renal, and postrenal uremia. (cdc.gov)
Genomics1
  • We have published a paper describing the dynamic data linkage in Microbial Genomics ( press release ). (me.uk)
Bioassays1
  • Therefore there is a need for novel eukaryotic microbial bioassays that will be relevant to higher eukaryotes such as animals and plants. (biomedcentral.com)
Efficacy2
  • A Practical handbook for antimalarial drug therapeutic efficacy testing for the district health worker. (who.int)
  • Postdoc Justine Rudkin has been working in the lab with Derrick Crook , Sir John Bell and others to measure the efficacy of antibody tests for the UK Government. (me.uk)
Concentrations2
  • To each well were placed 100mL of BHI doubly concentrated, 100μL of the tinctures in concentrations that ranged from 100 to 0.78 mg/mL and 10 mL of microbial inoculum (1.5x108 UFC/mL). (bvsalud.org)
  • NT-proBNP concentrations were the grea test with the smallest Hb (4.0-5.9 g/dl), hematocrit and red blood cell (RBC) concentrations, respectively. (nel.edu)
Skin sensitivity1
Enzymes2
  • Fermentation is the process of bioconversion of organic substances by microorganisms and/or enzymes (complex proteins) of microbial, plant or animal origin. (fao.org)
  • Many of these microbial metabolites (e.g. flavour compounds, amino acids, organic acids, enzymes, xanthan gums, alcohol etc.) are produced at the industrial level in both developed and developing countries for use in food processing applications. (fao.org)
Nitrogen3
  • We used a coupled carbon-climate model that accounts for the carbon cost to plants of supporting nitrogen-acquiring microbial symbionts to explore how nitrogen limitation affects global climate. (copernicus.org)
  • As such, our results suggest that carbon expenditures to support nitrogen-acquiring microbial symbionts have critical consequences for Earth's climate, and that carbon-climate models that omit these processes will overpredict the land carbon sink and underpredict climate change. (copernicus.org)
  • Nitrogen rates applied for the main crop promoted microbial biomass in spring soil sampling. (essopenarchive.org)
Permeability3
  • To officially test for intestinal permeability, the standard is to perform a lactulose/mannitol test. (robbwolf.com)
  • 2 Other permeability markers have been tested in a mice model including FITC-dextran 400 and ovalbumin measured in the plasma as well as polyethylene glycol measured in the urine. (robbwolf.com)
  • All oral permeability tests have been shown to be suitable in assessing intestinal barrier function. (robbwolf.com)
Organisms1
  • The close proximity of the middle ear to the brain and the increasing resistance of microbial organisms involved in otitis media make this pathology of great concern in children . (bvsalud.org)
Infection7
  • Usually, a blood specimen is mixed with test antigen to detect patient antibodies, most often in suspected fungal infection or pyogenic meningitis. (merckmanuals.com)
  • Your vet may run a blood test to rule out hormonal problems or endocrine diseases that may be to blame for your dog's ear infection. (vetericyn.com)
  • The combination of an initial cleaning, otoscopic examination of the ear canal and eardrum, and, if necessary, one of these five tests should be able to determine the root or underlying cause of your dog's ear infection. (vetericyn.com)
  • A fungal culture test is used to find out whether you have a fungal infection. (medlineplus.gov)
  • Your health care provider may order a fungal culture test if you have symptoms of a fungal infection. (medlineplus.gov)
  • You don't need any special preparations to test for a fungal infection. (medlineplus.gov)
  • BACKGROUND: With the potential impact of the COVID-19 pandemic on HIV preexposure prophylaxis (PrEP) care management, we assessed the number of PrEP users and sexually transmitted infection (STI) testing-eligible PrEP users, STI testing rates, and prevalence between prepandemic (January 1, 2018-March 31, 2020) and early-pandemic (April 1, 2020-September 30, 2020) periods. (cdc.gov)
Biogeochemical1
  • Thus, laboratory approaches to measure microbial fitness in biogeochemical gradients can be very useful to help identify likely selective pressures. (nature.com)
Antibody6
  • The test can measure IgM and IgG antibody titers or can be modified to detect certain antigens. (merckmanuals.com)
  • Precipitation tests measure an antigen or antibody in body fluids by the degree of visible precipitation of antigen-antibody complexes within a gel (agarose) or in solution. (merckmanuals.com)
  • Because a positive result requires a large amount of antibody or antigen, sensitivity is low. (merckmanuals.com)
  • Antibody testing can complement molecular assays for detecting COVID-19. (who.int)
  • This work was crucial in demonstrating the limitations of early blood-spot based tests, and the credibility of subsequent generations of antibody tests. (me.uk)
  • Justine has also been working in the lab with Sarah Walker to set up robots for her large antibody testing cohort study . (me.uk)
Soils3
  • It is critical to understand the complex relationships, including the absence or presence of terminal electron acceptors, that govern microbial competition and coexistence in anaerobic soils and sediments, because subsurface microbial processes can effect greenhouse gas emissions from soils, possibly resulting in impacts at the global scale. (frontiersin.org)
  • Soil carbon is intimately related to the living part of the organic matter, as represented by the soil microbial biomass, which mediates the decomposition, mineralization, and immobilization of organic carbon available in soils under different land-use systems. (essopenarchive.org)
  • We evaluated MBC and microbial respiration in soils under five different land-use systems and two contrasting seasons, at a regional scale in Santa Catarina State, Southern Brazil. (essopenarchive.org)
Fungus1
  • The test may help identify the type of fungus that you have. (medlineplus.gov)
Enzyme2
  • Because sensitivities of most enzyme immunoassays are high, they are usually used for screening. (merckmanuals.com)
  • COVID-19 can be diagnosed by detection of RNA gene targets (e.g. spike protein (S), an envelope protein (E), nucleocapsid protein (N), RNA-dependent RNA polymerase enzyme, and ORF1 gene) (4-6) either by nucleic acid amplification testing or detection of virus-specific proteins by antigen testing (7,8). (who.int)
Antigen1
  • The antigens (either dietary related or microbial or viral) pass through the weakened junctional complex(JC), they are presented by an antigen-presenting cell (APC) to the T-cells (a lymphocyte produced by the Thymus gland). (robbwolf.com)
Logistic regression2
  • Three-level logistic regression was performed between microbial richness/abundance/functional pathways and the occurrence of asthma and rhinitis symptoms. (biomedcentral.com)
  • A Whitney U test or t test, Pearson chi-square test, and multiple logistic regression analyses were gradually used for screening the adjusted factors of SSI. (bvsalud.org)
Metabolism2
  • Microbial bioluminescence is a branch of the electron transport chain [ 7 ] and as electron transport is involved in cell metabolism, any disruption to this system e.g. by the presence of toxins, will have an effect on light output. (biomedcentral.com)
  • The information greatly enriches our understanding on microbial oleaginicity and Pi-related metabolism. (biomedcentral.com)
Swab1
  • Thanks to a pre-existing collaboration between our group, Public Health England and UK Biobank , we were in a position to help rapidly facilitate COVID-19 research via SARS-CoV-2 PCR-based swab test results. (me.uk)
Pathogens1
  • Evaluate rapid screening tests for detecting foodborne pathogens in animal feed and the environment. (fda.gov)
Results9
  • Antimicrobial therapy should be based on culture and sensitivity results and should be pathogen-specific. (medscape.com)
  • In-process and final sterility tests are initiated prior to shipping, but the final results are not available for up to 7 days. (rxlist.com)
  • PROVENGE is released for shipping based on acceptable results from 2-day incubation of the in-process sterility test. (rxlist.com)
  • If results are positive, the body fluid is serially diluted and tested. (merckmanuals.com)
  • This article also provides access to three free On-Line calculators that enable the probability of detecting a pathogen in a food, the number of samples required to test to meet a food standard and how to calculate the prevalence of a pathogen when all the samples taken for testing return negative results. (dairyscience.info)
  • We conducted the first indoor microbiome survey in urban/rural environments with shotgun metagenomics, and the results revealed high-resolution microbial taxonomic and functional profiling and potential health effects. (biomedcentral.com)
  • Traditional CCIT methods, such as microbial challenge tests or blue dye ingress tests, are described as methods associated with probabilistic outcomes having some uncertainty in the results which, in turn, makes such methods difficult to quantitatively validate for the detection of critical leaks (1). (pharmtech.com)
  • These results clarify which ions are likely causal factors that impact the microbial community at this field site and are not merely correlated with taxonomic shifts. (nature.com)
  • Beginning mid-March, we worked to provide regular (usually weekly) updates of tests results, which were made available to all UK Biobank researchers beginning April 17th. (me.uk)
Screening9
  • Current screening methodologies for detecting infectious airborne influenza virus are limited and lack sensitivity. (cdc.gov)
  • The Western blot typically has good sensitivity, although often less than that of screening tests such as ELISA, but generally is highly specific. (merckmanuals.com)
  • Thus, it is usually used to confirm a positive result obtained with a screening test. (merckmanuals.com)
  • Evaluate screening tests for drug residues in animal-derived foods. (fda.gov)
  • The division is also responsible for reviewing drug residue diagnostic tests (screening tests) and for determining accurate product labeling. (fda.gov)
  • Among STI testing-eligible PrEP users who had 14 days between runout and next refill date, gonorrhea and chlamydia screening testing rates were 95.1% for prepandemic and 93.4% for early pandemic ( P = 0.1011). (cdc.gov)
  • Screening tests can be of use in eases are considered to be preventable. (cdc.gov)
  • Keywords Allergy Æ Hypersensitivity Æ Screening tests Æ many chemicals can produce irritant contact dermatitis. (cdc.gov)
  • It is also used as a sensitive screening test for occult alcoholism. (cdc.gov)
Allergy2
  • 3. Has a known sensitivity, intolerability, or allergy to eggs or any of the study product ingredients. (who.int)
  • [4] Positive tests, however, may not mean there is a significant allergy to the substance in question. (mdwiki.org)
Microbiological2
  • While the use of HACCP systems significantly reduces the need for microbiological end point testing of foods, sampling schemes and microbial analysis have important roles in system validation and quality assurance. (dairyscience.info)
  • The chemical-physical characteristics have shown correlations with microbiological variables related to the soil microbial C-dynamics. (essopenarchive.org)
20202
  • Método: revisión integradora, realizada de febrero a diciembre de 2020, en las bases de datos electrónicas US National Library of Medicine, Medical Literature Analysis and Retrieval System Online y Virtual Health Library. (bvsalud.org)
  • The health benefits highlighted for topical CBD skincare cosmetics are hard to believe sometimes, as consumers have every right to be skeptical in 2020 as regulations form and third party testing verification practices are standardized. (healthmj.com)
Diffusion1
  • There are many types of precipitation tests (eg, Ouchterlony double diffusion, counterimmunoelectrophoresis), but their applications are limited. (merckmanuals.com)
Culture5
  • Every effort should be made to obtain a specimen for culture and sensitivity. (medscape.com)
  • All subjects whose samples were sterile or contaminated (poly-microbial culture ) and those who received antibiotic - corticosteroid therapy were excluded. (bvsalud.org)
  • What is a Fungal Culture Test? (medlineplus.gov)
  • Why do I need a fungal culture test? (medlineplus.gov)
  • To do a fungal culture test you will need to provide a sample of cells or fluid from the part of your body where the fungi may be growing. (medlineplus.gov)
Pharmaceutical3
  • This article summarizes the current state of container closure integrity testing in the pharmaceutical and biopharmaceutical industries and outlines possible approaches for developing a CCIT strategy. (pharmtech.com)
  • Various enterprises, especially pharmaceutical companies and food industries, have been adopting RMM as they have demonstrated improved testing quality and generated considerable savings for businesses. (europeanpharmaceuticalreview.com)
  • Recirculating negative pressure cleanrooms are commonly selected for purity testing, weighing, capsulizing, and packaging pharmaceutical powders. (laboratory-equipment.com)
Specimen1
  • Titers can be determined by serially diluting the specimen as for agglutination tests. (merckmanuals.com)
Browsing by Subject Microbial Sensitivity Tests
Browsing by Subject "Microbial Sensitivity Tests" (extranet.who.int)
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Clinical and laboratory profile of patients with tuberculosis/HIV coinfection at a national referral centre: a case series
Clinical and laboratory profile of patients with tuberculosis/HIV coinfection at a national referral centre: a case series (extranet.who.int)
Manual for the laboratory identification and antimicrobial susceptibility testing of bacterial pathogens of public health...
Manual for the laboratory identification and antimicrobial susceptibility testing of bacterial pathogens of public health... (extranet.who.int)
Microbiological and chemical profile of Lebanese qishta [‎heat-coagulated milk]‎
Microbiological and chemical profile of Lebanese qishta [‎heat-coagulated milk]‎ (extranet.who.int)
Study of anti-bacterial effectiveness of acqueous extracts of garlic]‎
Study of anti-bacterial effectiveness of acqueous extracts of garlic]‎ (extranet.who.int)
Prevalence of asymptomatic bacteriuria in pregnant women in Sharjah, United Arab Emirates
Prevalence of asymptomatic bacteriuria in pregnant women in Sharjah, United Arab Emirates (extranet.who.int)
Standardisation de l'antibiogramme de Neisseria meningitidis : détection des souches relativement résistantes à la...
Standardisation de l'antibiogramme de Neisseria meningitidis : détection des souches relativement résistantes à la... (extranet.who.int)
Use of thermonuclease testing to identify Staphylococcus aureus by direct examination of blood cultures
Use of thermonuclease testing to identify Staphylococcus aureus by direct examination of blood cultures (extranet.who.int)
Prevalence and etiology of urinary stones in hospitalized patients in Baghdad
Prevalence and etiology of urinary stones in hospitalized patients in Baghdad (extranet.who.int)
Utilisation de l'artésunate-pyronaridine pour le traitement du paludisme non compliqué
Utilisation de l'artésunate-pyronaridine pour le traitement du paludisme non compliqué (extranet.who.int)
Manual de laboratorio para la identificación y prueba de ausceptibilidad a los antimicrobianos de patógenos bacterianos de...
Manual de laboratorio para la identificación y prueba de ausceptibilidad a los antimicrobianos de patógenos bacterianos de... (extranet.who.int)
Isolation of Yersinia enterocolitica from cases of acute appendicitis and ice-cream
Isolation of Yersinia enterocolitica from cases of acute appendicitis and ice-cream (extranet.who.int)
School of Medicine, Dentistry and Biomedical Sciences - Research output - Queen's University Belfast
School of Medicine, Dentistry and Biomedical Sciences - Research output - Queen's University Belfast (pure.qub.ac.uk)
FARMACIA Y BIOQUIMICA - Research output - San Luis Gonzaga National University of Ica
FARMACIA Y BIOQUIMICA - Research output - San Luis Gonzaga National University of Ica (cris.unica.edu.pe)
Immunologic Tests for Infectious Disease - Infectious Diseases - Merck Manuals Professional Edition
Immunologic Tests for Infectious Disease - Infectious Diseases - Merck Manuals Professional Edition (merckmanuals.com)
Details - Public Health Image Library(PHIL)
Details - Public Health Image Library(PHIL) (phil.cdc.gov)
BF Parasit Dis F
BF Parasit Dis F (wetwebmedia.com)
WHO EMRO | Bacterial etiologic agents of urinary tract infection in children in the Islamic Republic of Iran | Volume 3, issue...
WHO EMRO | Bacterial etiologic agents of urinary tract infection in children in the Islamic Republic of Iran | Volume 3, issue... (emro.who.int)