Central Nervous System Stimulants
A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
Substance Abuse Detection
Dopamine Plasma Membrane Transport Proteins
One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action.
Dopamine Uptake Inhibitors
Gas Chromatography-Mass Spectrometry
Vesicular Monoamine Transport Proteins
Striped GRAY MATTER and WHITE MATTER consisting of the NEOSTRIATUM and paleostriatum (GLOBUS PALLIDUS). It is located in front of and lateral to the THALAMUS in each cerebral hemisphere. The gray substance is made up of the CAUDATE NUCLEUS and the lentiform nucleus (the latter consisting of the GLOBUS PALLIDUS and PUTAMEN). The WHITE MATTER is the INTERNAL CAPSULE.
A phenethylamine found in EPHEDRA SINICA. PSEUDOEPHEDRINE is an isomer. It is an alpha- and beta-adrenergic agonist that may also enhance release of norepinephrine. It has been used for asthma, heart failure, rhinitis, and urinary incontinence, and for its central nervous system stimulatory effects in the treatment of narcolepsy and depression. It has become less extensively used with the advent of more selective agonists.
Dose-Response Relationship, Drug
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.
Drugs designed and synthesized, often for illegal street use, by modification of existing drug structures (e.g., amphetamines). Of special interest are MPTP (a reverse ester of meperidine), MDA (3,4-methylenedioxyamphetamine), and MDMA (3,4-methylenedioxymethamphetamine). Many drugs act on the aminergic system, the physiologically active biogenic amines.
Drug and Narcotic Control
The observable, measurable, and often pathological activity of an organism that portrays its inability to overcome a habit resulting in an insatiable craving for a substance or for performing certain acts. The addictive behavior includes the emotional and physical overdependence on the object of habit in increasing amount or frequency.
Drugs capable of inducing illusions, hallucinations, delusions, paranoid ideations, and other alterations of mood and thinking. Despite the name, the feature that distinguishes these agents from other classes of drugs is their capacity to induce states of altered perception, thought, and feeling that are not experienced otherwise.
The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.
A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl.
Drugs designed to treat inflammation of the nasal passages, generally the result of an infection (more often than not the common cold) or an allergy related condition, e.g., hay fever. The inflammation involves swelling of the mucous membrane that lines the nasal passages and results in inordinate mucus production. The primary class of nasal decongestants are vasoconstrictor agents. (From PharmAssist, The Family Guide to Health and Medicine, 1993)
Collection of pleomorphic cells in the caudal part of the anterior horn of the LATERAL VENTRICLE, in the region of the OLFACTORY TUBERCLE, lying between the head of the CAUDATE NUCLEUS and the ANTERIOR PERFORATED SUBSTANCE. It is part of the so-called VENTRAL STRIATUM, a composite structure considered part of the BASAL GANGLIA.
Highly sensitive quantitation of methamphetamine by time-resolved fluoroimmunoassay using a new europium chelate as a label. (1/1448)A simple and highly sensitive time-resolved fluoroimmunoassay of methamphetamine (MA) using a new fluorescent europium chelate (BHHCT-Eu3+) as a label is described. Two variations of competitive immunoassay were attempted. In the first (one-step) assay, microtiter plates coated with anti-MA were used, and the new label was bound to a conjugate of bovine serum albumin and N-(4-aminobutyl)-MA (MA-BSA). In the second (two-step) assay, instead of the labeled MA-BSA, biotinylated MA-BSA and BHHCT-Eu3+-labeled streptavidin-BSA were used. The lowest measurable concentrations of MA for the one-step and the two-step methods were 1 ng/mL (25 pg/assay) and 1 pg/mL (25 fg/assay), respectively. These were 10 to 1000 times superior to the detection limits of MA in any other immunoassay. Intra-assay coefficient of variation was approximately 2-8% at eight different concentrations (n = 4). Analysis of 34 urine samples with the new method and conventional gas chromatography showed a good correlation (r = 0.954). The high detectability of the present assay also enabled segmental hair analysis with a few centimeters of a hair. (+info)
Determination of pyrolysis products of smoked methamphetamine mixed with tobacco by tandem mass spectrometry. (2/1448)This study examines the pyrolysis products of smoked methamphetamine mixed with tobacco that was trapped with a C8 adsorbent cartridge and then detected by gas chromatography-tandem mass spectrometry. According to the results, the mainstream smoke contains 2-methylpropyl-benzene, 2-chloropropyl-benzene, 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one, 3-ethyl-phenol, methamphetamine, dimethylamphetamine, hydroquinone, 3-methyl-5-(1-methylethyl)-methylcarbamate phenol, N-methyl-N-(2-phenylethyl)-acetamide, 4-(3-hydroxy-1-butenyl)-3,5,5-trimethyl-2-cyclohexene-1-one, propanoic acid, N-acetylmethamphetamine, phenyl ester, and furfurylmethylamphetamine. In addition, the compounds in sidestream smoke are 2-propenyl benzene, phenylacetone, methamphetamine, dimethylamphetamine, benzyl methyl ketoxime, 3,4-dihydro-2-naphthalenone, N-folmyamphetamine, N-acetylamphetamine, bibenzyl, N-folmylmethamphetamine, N-acetylmethamphetamine, N-propionymethamphetamine, and furfurylmethylamphetamine. Moreover, the presence of methamphetamine promotes the oxidation of the tobacco components. (+info)
Toxicological findings in a fatal ingestion of methamphetamine. (3/1448)This paper presents the case history of a fatality caused by the complications brought about by the presence of methamphetamine and ethanol. Drug concentrations are reported from samples obtained approximately 15 min after the subject was last observed to be chewing what was then believed to be gum, 3 h after the initial toxic symptoms were displayed, 6, 11, and 22 h later. The subjects conditions deteriorated over the course of this time, and he was declared dead 33 h after the initial display of toxic symptoms. The toxicological findings and concentration levels of the reported biological specimens concurred with the expected findings in a case of methamphetamine toxicity. (+info)
Effects of stimulants of abuse on extrapyramidal and limbic neuropeptide Y systems. (4/1448)Neuropeptide Y (NPY), an apparent neuromodulating neuropeptide, has been linked to dopamine systems and dopamine-related psychotic disorders. Because of this association, we determined and compared the effects of psychotomimetic drugs on extrapyramidal and limbic NPY systems. We observed that phencyclidine, methamphetamine (METH), (+)methylenedioxymethamphetamine (MDMA), and cocaine, but not (-)MDMA, similarly reduced the striatal content of NPY-like immunoreactivity from 54% (phencyclidine) to 74% [(+) MDMA] of control. The effects of METH on NPY levels in the nucleus accumbens, caudate nucleus, globus pallidus, and substantia nigra were characterized in greater detail. We observed that METH decreased NPY levels in specific regions of the nucleus accumbens and the caudate, but had no effect on NPY in the globus pallidus or the substantia nigra. The dopamine D1 receptor antagonist SCH-23390 blocked these effects of METH, suggesting that NPY levels throughout the nucleus accumbens and the caudate are regulated through D1 pathways. The D2 receptor antagonist eticlopride did not appear to alter the METH effect, but this was difficult to determine because eticlopride decreased NPY levels by itself. A single dose of METH was sufficient to lower NPY levels, in some, but not all, regions examined. The effects on NPY levels after multiple METH administrations were substantially greater and persisted up to 48 h after treatment; this suggests that synthesis of this neuropeptide may be suppressed even after the drug is gone. These findings suggest that NPY systems may contribute to the D1 receptor-mediated effects of the psychostimulants. (+info)
N-oxygenation of amphetamine and methamphetamine by the human flavin-containing monooxygenase (form 3): role in bioactivation and detoxication. (5/1448)(+)- And (-)-amphetamine and methamphetamine were N-oxygenated by the cDNA expressed adult human flavin-containing monooxygenase form 3 (FMO3), their corresponding hydroxylamines. Two major polymorphic forms of human FMO3 were studied, and the results suggested preferential N-oxygenation by only one of the two enzymes. Chemically synthesized (+/-)-amphetamine hydroxylamine was also a substrate for the human FMO3 and it was converted to phenylpropanone oxime with a stereoselectivity ratio of trans/cis of 5:1. Human FMO3 also N-oxygenated methamphetamine to produce methamphetamine hydroxylamine. Methamphetamine hydroxylamine was also N-oxygenated by human FMO3, and the ultimate product observed was phenylpropanone. For amphetamine hydroxylamine, studies of the biochemical mechanism of product formation were consistent with the production of an N, N-dioxygenated intermediate that lead to phenylpropanone oxime. This was supported by the observation that alpha-deutero (+/-)-amphetamine hydroxylamine gave an inverse kinetic isotope effect on product formation in the presence of human FMO3. For methamphetamine, the data were consistent with a mechanism of human FMO3-mediated N,N-dioxygenation but the immediate product, a nitrone, rapidly hydrolyzed to phenylpropanone. The pharmacological activity of amphetamine hydroxylamine, phenylpropanone oxime, and methamphetamine hydroxylamine were examined for effects at the human dopamine, serotonin, and norepinephrine transporters. Amphetamine hydroxylamine and methamphetamine hydroxylamine were apparent substrates for the human biogenic amine transporters but phenylpropanone oxime was not. Presumably, phenylpropanone oxime or nitrone formation from amphetamine and methamphetamine, respectively, represents a detoxication process. Because of the potential toxic nature of amphetamine hydroxylamine and methamphetamine hydroxylamine metabolites and the polymorphic nature of N-oxygenation, human FMO3-mediated metabolism of amphetamine or methamphetamine may have clinical consequences. (+info)
Behavioral, toxic, and neurochemical effects of sydnocarb, a novel psychomotor stimulant: comparisons with methamphetamine. (6/1448)Sydnocarb (3-(beta-phenylisopropyl)-N-phenylcarbamoylsydnonimine) is a psychostimulant in clinical practice in Russia as a primary and adjunct therapy for a host of psychiatric disorders, including schizophrenia and depression. It has been described as a stimulant with an addiction liability and toxicity less than that of amphetamines. The present study undertook to evaluate the psychomotor stimulant effects of sydnocarb in comparison to those of methamphetamine. Sydnocarb increased locomotor activity of mice with reduced potency (approximately 10-fold) and efficacy compared with methamphetamine. Sydnocarb blocked the locomotor depressant effects of haloperidol at doses that were inactive when given alone. The locomotor stimulant effects of both methamphetamine and sydnocarb were dose-dependently blocked by the dopamine D1 and D2 antagonists SCH 39166 and spiperone, respectively; blockade generally occurred at doses of the antagonists that did not depress locomotor activity when given alone. In mice trained to discriminate methamphetamine from saline, sydnocarb fully substituted for methamphetamine with a 9-fold lower potency. When substituted for methamphetamine under self-administration experiments in rats, 10-fold higher concentrations of sydnocarb maintained responding by its i.v. presentation. Sydnocarb engendered stereotypy in high doses with approximately a 2-fold lower potency than methamphetamine. However, sydnocarb was much less efficacious than methamphetamine in inducing stereotyped behavior. Both sydnocarb and methamphetamine increased dialysate levels of dopamine in mouse striatum; however, the potency and efficacy of sydnocarb was less than methamphetamine. The convulsive effects of cocaine were significantly enhanced by the coadministration of nontoxic doses of methamphetamine but not of sydnocarb. Taken together, the present findings indicate that sydnocarb has psychomotor stimulant effects that are shared by methamphetamine while demonstrating a reduced behavioral toxicity. (+info)
Does nicotine modify the psychotoxic effect of methamphetamine? Assessment in terms of locomotor sensitization in mice. (7/1448)In this study, effects of nicotine on locomotor sensitization to methamphetamine in mice were investigated to assess whether nicotine modified induction and expression of psychotoxic action of methamphetamine. Although nicotine (0.03-1 mg/kg s.c.) had no effect at first administration, 5-time nicotine administrations at 3-day intervals progressively developed a significant locomotor stimulant effect, and caused an enhanced sensitivity (cross-sensitization) to methamphetamine (2 mg/kg s.c.). Five-time administrations of methamphetamine (2 mg/kg) at 3-day intervals produced not only a locomotor sensitization to methamphetamine itself, but also a cross-sensitization to nicotine (0.1-1 mg/kg). Nicotine (0.03-1 mg/kg) did not affect the locomotor stimulant effect of methamphetamine (2 mg/kg) in the drug-naive mice. However, nicotine acted dose-dependently to reduce the progressive enhancement of the locomotor stimulant effect of methamphetamine during 5-time repeated administrations. Mice treated with coadministration of methamphetamine with nicotine (1 mg/kg) showed less sensitization to methamphetamine than mice treated with methamphetamine alone. In addition, nicotine (1 mg/kg) inhibited the locomotor stimulant effect of methamphetamine in mice sensitized to methamphetamine. These results suggest that methamphetamine and nicotine produce a symmetrical cross-sensitization, although nicotine may act to inhibit the induction and expression of locomotor sensitization to methamphetamine in mice. (+info)
Synergistic interactions between ampakines and antipsychotic drugs. (8/1448)Tests were made for interactions between antipsychotic drugs and compounds that enhance synaptic currents mediated by alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid-type glutamate receptors ("ampakines"). Typical and atypical antipsychotic drugs decreased methamphetamine-induced hyperactivity in rats; the effects of near or even subthreshold doses of the antipsychotics were greatly enhanced by the ampakines. Interactions between the ampakine CX516 and low doses of different antipsychotics were generally additive and often synergistic. The ampakine did not exacerbate neuroleptic-induced catalepsy, indicating that the interaction between the different pharmacological classes was selective. These results suggest that positive modulators of cortical glutamatergic systems may be useful adjuncts in treating schizophrenia. (+info)
Study of Medical Treatment for Methamphetamine Addiction - Full Text View - ClinicalTrials.gov
Currently there are no medications approved for the treatment of methamphetamine addiction. Bupropion is an antidepressant that is approved by the Food and Drug Administration (FDA) for the treatment of depression and for cigarette smoking cessation but is not approved by the FDA for the treatment of methamphetamine addiction. Preliminary research studies suggest that bupropion may help people receiving treatment for methamphetamine addiction to reduce or to stop their methamphetamine use. But results of these studies also suggest that bupropion may help certain groups of patients more than others, such as men versus women and light versus heavy methamphetamine users, although the reasons for this difference are not known. One possibility is that a persons genetic make up may influence whether or not they respond to treatment with bupropion for methamphetamine addiction.. The purpose of the study is to determine if bupropion is can help people reduce or stop their methamphetamine use and to ...
Prenatal Methamphetamine Exposure | Drug War Facts
(Prenatal Methamphetamine Exposure) Although research on the medical and developmental effects of prenatal methamphetamine exposure is still in its early stages, our experience with almost 20 years of research on the chemically related drug, cocaine, has not identified a recognizable condition, syndrome or disorder that should be termed crack baby nor found the degree of
Effects of chronic methamphetamine exposure on heart function in uninfected and retrovirus-infected mice<...
TY - JOUR. T1 - Effects of chronic methamphetamine exposure on heart function in uninfected and retrovirus-infected mice. AU - Yu, Qianli. AU - Montes, Sergio. AU - Larson, Douglas F. AU - Watson, Ronald R. PY - 2002/7/12. Y1 - 2002/7/12. N2 - Methamphetamine (MA) increases catecholamine levels, which have detrimental effects on heart function through vasoconstriction, myocardial hypertrophy, and fibrosis. Murine retrovirus infection induces dilated cardiomyopathy (DCM). The present study investigated the cardiovascular effects of chronic MA treatment on uninfected and retrovirus-infected mice. C57BL/6 mice were studied after 12 weeks treatment. The four study groups were (group I) uninfected, MA placebo; (group II) infected, MA placebo; (group III) uninfected, MA treatment; and (group IV) infected and MA treatment. MA injections were given i.p. once a day for 5 days/week with a increasing dose from 15 mg/kg to 40 mg/kg. Left ventricular mechanics were measured in situ a using Millar conductance ...
The role of system Xc<sup>−</sup> in methamphetamine-induced dopaminergic neurotoxicity...
TY - JOUR. T1 - The role of system Xc− in methamphetamine-induced dopaminergic neurotoxicity in mice. AU - Dang, Duy Khanh. AU - Shin, Eun Joo. AU - Tran, Hai Quyen. AU - Kim, Dae Joong. AU - Jeong, Ji Hoon. AU - Jang, Choon Gon. AU - Nah, Seung Yeol. AU - Sato, Hideyo. AU - Nabeshima, Toshitaka. AU - Yoneda, Yukio. AU - Kim, Hyoung Chun. PY - 2017/9. Y1 - 2017/9. N2 - The cystine/glutamate antiporter (system Xc−, Sxc) transports cystine into cell in exchange for glutamate. Since xCT is a specific subunit of Sxc, we employed xCT knockout mice and investigated whether this antiporter affected methamphetamine (MA)-induced dopaminergic neurotoxicity. MA treatment significantly increased striatal oxidative burdens in wild type mice. xCT inhibitor [i.e., S-4-carboxy-phenylglycine (CPG), sulfasalazine] or an xCT knockout significantly protected against these oxidative burdens. MA-induced increases in Iba-1 expression and Iba-1-labeled microglial immunoreactivity (Iba-1-IR) were significantly ...
Higher cortical and lower subcortical metabolism in detoxified methamphetamine abusers<...
TY - JOUR. T1 - Higher cortical and lower subcortical metabolism in detoxified methamphetamine abusers. AU - Volkow, N. D.. AU - Chang, L.. AU - Wang, G. J.. AU - Fowler, J. S.. AU - Franceschi, D.. AU - Sedler, M. J.. AU - Gatley, S. J.. AU - Hitzemann, R.. AU - Ding, Y. S.. AU - Wong, C.. AU - Logan, J.. PY - 2001/3/21. Y1 - 2001/3/21. N2 - Objective: Methamphetamine has raised concerns because it may be neurotoxic to the human brain. Although prior work has focused primarily on the effects of methamphetamine on dopamine cells, there is evidence that other neuronal types are affected. The authors measured regional brain glucose metabolism, which serves as a marker of brain function, to assess if there is evidence of functional changes in methamphetamine abusers in regions other than those innervated by dopamine cells. Method: Fifteen detoxified methamphetamine abusers and 21 comparison subjects underwent positron emission tomography following administration of [18F]fluorodeoxyglucose. Results: ...
Prenatal methamphetamine exposure - Wikipedia
Prenatal methamphetamine exposure (PME) is the exposure of a fetus to methamphetamine when a woman uses the drug during her pregnancy. Methamphetamine (MA) has shown increasing popularity in the past two decades among women of childbearing age. Methamphetamine is second only to cannabis as the most widely used illegal drug, which may be because it is relatively cheap and easy to manufacture. Yet, to this date, the effects of PME on the developing fetus have not been well characterized and even less is known regarding the effects on development in childhood. Although few studies have established a pattern of MA use in pregnant users, it is important that researchers seek to determine this pattern to examine a possible dose-response relationship between MA use and neonatal outcomes. The recent increase in MA use in the United States, particularly in the South and Midwest, highlights the need for a better understanding of the short-term and long-term effects of MA use during pregnancy upon newborns ...
Sabinet | A comparative study of the effects of methamphetamine on memory in existing and recovering addicts from a South...
Memory is a complex of systems by which an organism registers, stores and retrieves exposure to an event or experience. Literature purports that methamphetamine users and dependents have been found to exhibits signs of memory impairment. The aim of the research was to establish the possible existence of significant differences in memory in current methamphetamine users, recovering methamphetamine users, and a matched drug naïve control group. Cognitive functioning was assessed via a neurocognitive test battery that examined the memory of 14 current methamphetamine users, 17 recovering methamphetamine addicts, and 18 drug naïve control participants who were matched according to the demographic variables of age, gender and educational status. The results indicated that recovering methamphetamine users experienced the greatest impairment in memory in comparison to both the control group and current users of methamphetamine. The current users of methamphetamine also experienced some impairment in memory
Methamphetamine self-administration causes persistent striatal dopaminergic alterations and mitigates the deficits caused by a...
TY - JOUR. T1 - Methamphetamine self-administration causes persistent striatal dopaminergic alterations and mitigates the deficits caused by a subsequent methamphetamine exposure. AU - McFadden, Lisa M.. AU - Hadlock, Greg C.. AU - Allen, Scott C.. AU - Vieira-Brock, Paula L.. AU - Stout, Kristen A.. AU - Ellis, Jonathan D.. AU - Hoonakker, Amanda J.. AU - Andrenyak, David M.. AU - Nielsen, Shannon M.. AU - Wilkins, Diana G.. AU - Hanson, Glen R.. AU - Fleckenstein, Annette E.. PY - 2012/2/1. Y1 - 2012/2/1. N2 - Preclinical studies have demonstrated that repeated methamphetamine (METH) injections (referred to herein as a binge treatment) cause persistent dopaminergic deficits. A few studies have also examined the persistent neurochemical impact of METH self-administration in rats, but with variable results. These latter studies are important because: 1) they have relevance to the study of METH abuse; and 2) the effects of noncontingent METH treatment do not necessarily predict effects of ...
Methamphetamine Abuse - American Family Physician
Methamphetamine is a stimulant commonly abused in many parts of the United States. Most methamphetamine users are white men 18 to 25 years of age, but the highest usage rates have been found in native Hawaiians, persons of more than one race, Native Americans, and men who have sex with men. Methamphetamine use produces a rapid, pleasurable rush followed by euphoria, heightened attention, and increased energy. Possible adverse effects include myocardial infarction, stroke, seizures, rhabdomyolysis, cardiomyopathy, psychosis, and death. Chronic methamphetamine use is associated with neurologic and psychiatric symptoms and changes in physical appearance. High-risk sexual activity and transmission of human immunodeficiency virus are also associated with methamphetamine use. Use of methamphetamine in women who are pregnant can cause placental abruption, intrauterine growth retardation, and preterm birth, and there can be adverse consequences in children exposed to the drug. Treatment of methamphetamine
Varenicline as a Treatment for Methamphetamine Dependence - Full Text View - ClinicalTrials.gov
This study is part of an effort to develop treatments for methamphetamine abuse. Varenicline is a drug that changes levels of certain brain chemicals that may also be useful in helping people to stop using methamphetamine. Our goal is to determine the safety and effects of varenicline (1 and 2 mg, daily, vs. a placebo) when it is used before experimental administration of methamphetamine, on a number of physical and psychological measures; specifically blood pressure, heart rate, and how you feel after taking methamphetamine. The secondary purpose is to determine the effects of treatment with varenicline (1 and 2 mg daily), compared to treatment with placebo, on the reinforcing effects of methamphetamine by measuring methamphetamine self-administration in methamphetamine-dependent human volunteers ...
Crystal Meth Treatment Burnsville MN - meth treatment, Burnsville MN meth addiction, Burnsville MN post-mortem shot,...
Crystal Meth Treatment in Burnsville, MN. Find phone numbers, addresses and information about Crystal Meth Treatment in Burnsville.
Methamphetamines | Methamphetamine Abuse.org
Methamphetamine can increase the release and even block the reuptake of the brain chemical dopamine. This leads to higher levels of dopamine in the brain which is common for drug abusers. Dopamine is responsible for reward, experience of pleasure, motivation and motor function. Since methamphetamine has the ability to release dopamine quickly in the brain, the reward sections of the brain experience an intense euphoria or a rush once the drug has been smoked, snorted, or injected into the body.. Using methamphetamine for a long period of time can significantly change how the brain is able to function. These functions can include reduced motor skills and impaired verbal learning. In other studies conducted, it also shows that chronic methamphetamine abusers have severe structural and even functional changes in the brain; in the memory and emotion areas. This is why many of the abusers of the drug have problems with emotional and cognitive situations.. Using methamphetamine for an extended period ...
Buy Methamphetamine (Crystal Meth) < resultsbyrw...
Purchase Cheap Methamphetamine (Crystal Meth) For Sale Without A Prescription. , Methamphetamine) you may experience long-term effects such as: dizziness or lightheadedness; headache; blurred vision; fatigue; low energy; heartburn; nausea; vomiting; muscle aches; dizziness and nausea; vomiting, diarrhea, muscle pain or muscle cramps; headache; sleepiness and difficulty concentrating; tingling in your left arm or legs; increased sensitivity to light and heat; trouble sleeping; dizziness and shortness of breath; muscle weakness. Some symptoms of abuse with Methamphetamine are not completely eliminated after the next dose takes effect. , Methamphetamine) and stop using Methamphetamine for a minimum of 6 months. It is illegal to sell or give Methamphetamine online without medical clearance. However, you can buy Methamphetamine online with legal credit cards online, so you dont need to worry about paying a fee.
History of Amphetamine and Methamphetamine
During the 1950s, methamphetamine use became associated with the Beat Generation. People associated with the Beat Generation were said to use methamphetamine recreationally. Methamphetamine was readily, legally available during this time period. Luminaries of the Beat Generation like author Jack Kerouac and poet W.H. Auden were said to use methamphetamine and other stimulants. In addition to use recreationally among the Beat Generation community, methamphetamine was used to treat depression and as a diet aid. Methamphetamine became widely used among college students, athletes, and truck drivers as a perceived means of enhancing their stamina and alertness.. During this area, addiction to methamphetamine became more commonplace. By 1959, methamphetamine was on the radar of regulatory authorities and others. ...
Methamphetamine Dependence - Effects of Methamphetamine Abuse - Methamphetamine Addiction Treatment
If you take methamphetamine, you should understand its potential for dependence and addiction. Learn the signs and symptoms and how to treat it.
Dynamics of Retail Methamphetamine Markets in New York City, 2007-2009
Study Purpose: The purpose of the study was to provide information about markets, distribution, and use of methamphetamine in New York City, both inside and outside of the MSM (men who have sex with men)/gay community. The study had four specific aims. (1) Pilot a research design using mixed qualitative/quantitative data collection methods in New York City methamphetamine markets with participants recruited using Respondent Driven Sampling. (2) Document, describe, and analyze the demographics and methamphetamine abuse behaviors of a sample of methamphetamine market participants. (3) Document, describe, and analyze the social networks of New York City methamphetamine market participants as users, buyers, and sellers of methamphetamine. (4) Document, describe, and analyze the market behaviors of New York City methamphetamine market participants as users, buyers, and sellers of methamphetamine. Study Design: Researchers piloted a version of Respondent Driven Sampling (RDS) to recruit different ...
Unmet healthcare need among women who use methamphetamine in San Francisco | RTI
Methamphetamine use has increased substantially in the United States since the 1990s. Few studies have examined the healthcare service needs of women who use methamphetamine. This study describes unmet medical needs in a community-based sample of women who use methamphetamine in San Francisco, CA. Women who use methamphetamine were recruited in San Francisco and participated in a computer-assisted survey (N = 298 HIV-negative women).
Methamphetamine Abuse Symptoms 800-303-2482 | Methamphetamine Abuse
Many people that struggle with Methamphetamine Abuse care for nothing but their high, so their unaware of the deadly Methamphetamine Abuse Symptoms.
Treatment for Crystal Methamphetamine (Meth) Addiction Des Moines IA - crystal meth, Des Moines IA neurochemical mechanisms,...
Treatment for Crystal Methamphetamine (Meth) Addiction in Des Moines, IA. Find phone numbers, addresses and information about Treatment for Crystal Methamphetamine (Meth) Addiction in Des Moines.
Methamphetamine Chiral Analysis, Urine
Methamphetamine exists as two enantiomers. The S(+) form, which is also called d methamphetamine, is an ingredient in a few legitimate pharmaceutical products available only by prescription, and can be illicitly synthesized from (-) ephedrine or (+) pseudoephedrine. The S(+) or d form of methamphetamine is generally considered a drug of abuse. On the other hand, the R(-) form, which is also called l-desoxyephedrine or l methamphetamine, is the active ingredient in Vicks inhalers, is a metabolite of the anti-Parkinson drug Selegiline, and is not a drug of abuse. When a specimen gives a confirmed positive result for methamphetamine, this test can be ordered. This test separates the enantiomers and will provide percentage-based information to help determine the source of methamphetamine in the specimen. Note that this test does not provide quantitations; it only provides the percentage(s) of each methamphetamine found in the urine. The urine should be previously tested for methamphetamine and ...
Use of methamphetamine increases risk of stroke in young people - News Lume
Recent studies and research shows that People who use methamphetamine are almost five times more likely to have a stroke caused by a bleed in the brain, many of which are fatal. We can add stroke to the list of terrible and devastating things that methamphetamine does, says Damian Zuloaga, of the University at Albany, New York.. Beyond the signature tooth decay known as meth mouth, methamphetamine also increases heart rate and blood pressure, and can trigger heart attacks. The drug can lead to psychosis, and has been linked to anxiety disorders, depression, and problems with movement similar to those seen in Parkinsons disease.. A handful of studies have also linked methamphetamine use to strokes. To explore further, Julia Lappin and her colleagues at the Australian National Drug and Alcohol Research Centre in Sydney sifted through published research on the topic.. The team specifically looked for research into people under the age of 45 - a group less likely to be affected by age-related ...
DEA - Publications - Methamphetamine Situation - Administrators Message
In June 1994, the law enforcement community was starkly reminded of the violence that surrounds methamphetamine trafficking and the changing nature of the methamphetamine trade that is spreading across the United States. Drug Enforcement Administration (DEA) Special Agent Richard Fass, acting in an undercover capacity, was attempting to make a purchase of methamphetamine in a Glendale, Arizona, strip-mall when he was ambushed, shot, and killed by four methamphetamine traffickers whose sole intent was to rob him. This incident ended in violence and tragedy, as do so many of the cases involving methamphetamine. Law enforcement officers are not the only ones to suffer from the violence and danger associated with methamphetamine innocent victims all too often are brought into the fray. Over the past year, two separate methamphetamine-related tragedies have captured the publics attention. First, during the summer in New Mexico, a father, while high on methamphetamine, beheaded his 14-year-old son. ...
Methamphetamine Treatment Project - Extended treatment for females 18-21 years old who are addicted to methamphetamine. |...
The Methamphetamine Treatment Project is collaborative effort between community and state to address the growing incidence of Methamphetamine use and abuse among youth in the state of South Dakota. The project is comprised of four phases, (1) stabilization, (2) intensive treatment, (3) structured living, and (4) community placement. Each phase will build on the proceeding phase. Most treatment programs do not adequately address the special needs of the Methamphetamine dependent adolescent client.
Study Shows High Rate of Dental Disease in Methamphetamine Users
The article describes a study done by eight professors from UCLA where they observed methamphetamine users dental health. The article provides statistics from the study about the prevalence of gum disease and cavities in methamphetamine users.
Methamphetamine Use and Sexual Risk Behavior among High School Students in Cape Town, South Africa
Objective: To investigate whether methamphetamine use is associated with sexual risk behavior among adolescents. Method: A cross-sectional survey of 1,561 male and female high school students in Cape Town (mean age 14.9 years) was conducted using items from the Problem Oriented Screening Instrument for Teenagers (POSIT) HIV Risk Scale. Results: Nine percent of the students had tried methamphetamine and 30% of male and 17% of female students reported sexual debut. Multinomial logistic regression analyses showed that methamphetamine use in the past year was significantly associated with being in a higher HIV/STI risk category (RRR = 2.1, 95% CI: 1.10-4.03, p & 0.05). Conclusions: Methamphetamine use, coupled with a high HIV prevalence in South Africa, raises serious cause for concern about the potential for methamphetamine to further exacerbate the prevalence and spread of HIV in Cape Town. © 2012 Taylor and Francis Group, LLC.. ...
Methamphetamine - Hawaii Drug Threat Assessment
Mexican criminal groups have replaced traditional Asian criminal groups as the primary transporters of methamphetamine. Mexican criminal groups are the primary transporters of Mexico-produced methamphetamine as well as methamphetamine produced in California. Law enforcement officials report that Mexican criminal groups transport methamphetamine into Hawaii from the West Coast, primarily California. Mexican criminal groups transport both powdered and crystal methamphetamine. Some powdered methamphetamine is converted to crystal methamphetamine in Mexico and on the West Coast for transportation to Hawaii.. Traditional Asian transporters of crystal methamphetamine--primarily Korean, Japanese, Filipino, and Vietnamese criminal groups--also transport the drug into Hawaii, but to a lesser extent than during the mid-1980s to early 1990s. In the early 1990s law enforcement authorities in Hawaii dismantled several large Asian, primarily Korean, criminal groups that dominated the transportation of crystal ...
KCSO Major Violators Unit drug lab investigation results in 40 pound Meth seizure. Two in custody. « Methamphetamine in the...
Within the past week, the Kern County Sheriffs Office Major Violators Unit concluded a Methamphetamine- to-Ice conversion narcotics lab investigation. The investigation led to a search warrant being served on Saturday, June 4th, at an auto-body repair business located near the intersection of Chamberlain and California Avenue, in Bakersfield. The search warrant resulted in the seizure of approximately four gallons of Methamphetamine solution and several pounds of Methamphetamine. The four gallons of Methamphetamine solution is estimated to contain/produce approximately 32 to 33 pounds of Methamphetamine. The estimated street value of the seized Methamphetamine is approximately 1.8 million dollars. Jose Cachu, age 44, of Lamont, and Jose Salinas, age 40, of Bakersfield, were both arrested at the business where the conversion lab was located. Both suspects were booked into the Kern County Jail for possession for sales, and manufacturing Methamphetamine. The investigation was a multi-agency ...
Early adversity strongly mediates relationship between prenatal Methamphetamine exposure, behavioral issues « Methamphetamine...
The prevalence of methamphetamine abuse during pregnancy in women seeking treatment tripled from 1994 to 2006, rising to 24% of all pregnant women admitted to federally funded treatment centers, according to the researchers. Eze and colleagues defined early adversity as the sum of multiple binary indicators, including self-reported maternal postnatal substance abuse, an annual household income less than $10,000, reported sexual or physical abuse by a caregiver, a maternal score on the Brief Symptom Inventory, maternal depression above average for the Beck Depression Inventory, quality of living environment below average on the HOME Inventory, community violence above average on the Lifestyle Interview, and social position below average for the Index of Social Position.. The researchers began recruiting for the Infant Development, Environment, and Lifestyle (IDEAL) longitudinal study in 2002. They enrolled 412 mother and infant pairs at four sites and identified participants as ...
Amphetamine and Methamphetamine Increase NMDAR-GluN2B Synaptic Currents in Midbrain Dopamine Neurons<...
TY - JOUR. T1 - Amphetamine and Methamphetamine Increase NMDAR-GluN2B Synaptic Currents in Midbrain Dopamine Neurons. AU - Li, Ming Hua. AU - Underhill, Suzanne M.. AU - Reed, Cheryl. AU - Phillips, Tamara J.. AU - Amara, Susan G.. AU - Ingram, Susan L.. PY - 2017/6/1. Y1 - 2017/6/1. N2 - The psychostimulants amphetamine (AMPH) and methamphetamine (MA) are widely abused illicit drugs. Here we show that both psychostimulants acutely increase NMDA receptor (NMDAR)-mediated synaptic currents and decrease AMPA receptor (AMPAR)/NMDAR ratios in midbrain dopamine neurons. The potentiation depends on the transport of AMPH into the cell by the dopamine transporter. NMDAR-GluN2B receptor inhibitors, ifenprodil, RO 25-6981, and RO 04-5595, inhibit the potentiation without affecting basal-evoked NMDA currents, indicating that NMDAR-GluN2B receptors are activated by AMPH. A selective peptide inhibitor of AMPH-dependent trafficking of the neuronal excitatory amino acid transporter 3 (EAAT3) blocks ...
Methamphetamine meaning in Hindi - मेथाम्फेटामिने मतलब हिंदी में - Translation
Methamphetamine meaning in Hindi : Get meaning and translation of Methamphetamine in Hindi language with grammar,antonyms,synonyms and sentence usages. Know answer of question : what is meaning of Methamphetamine in Hindi? Methamphetamine ka matalab hindi me kya hai (Methamphetamine का हिंदी में मतलब ). Methamphetamine meaning in Hindi (हिन्दी मे मीनिंग ) is मेथैंफ़ेटामीन.English definition of Methamphetamine : an amphetamine derivative (trade name Methedrine) used in the form of a crystalline hydrochloride; used as a stimulant to the nervous system and as an appetite suppressant
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Body dissatisfaction and methamphetamine use among HIV-positive gay and bisexual men: A pilot study<...
TY - JOUR. T1 - Body dissatisfaction and methamphetamine use among HIV-positive gay and bisexual men. T2 - A pilot study. AU - Theodore, Peter S.. AU - Achiro, Richard P.. AU - Duran, Ron E.F.. AU - Antoni, Michael H.. PY - 2011/10/24. Y1 - 2011/10/24. N2 - Methamphetamine use is strongly associated with risky sex and increased reports of HIV and other sexually transmitted infections among gay and bisexual men (GBM) who attend dance/circuit parties. The psychological mechanisms underlying methamphetamine use in this subculture, however, remain unclear. These exploratory findings are from a 2004 dataset measuring body dissatisfaction and drug use among 42 HIV-positive GBM in South Florida who attended at least one bar/club/circuit party within 3 months of participating. A multivariate regression model revealed that body dissatisfaction accounted for a small but significant amount of variance in methamphetamine use. Treatment implications and recommendations for future research are ...
Top 9 states for methamphetamine use
Last decade, positive drug tests among U.S. workers for methamphetamine had started to drop. That trend may be reversing, with positive rates dramatically higher in some states compared to others. The new statistics come from Quest Diagnostics annual report on U.S. worker drug use, based on more than six million urine tests collected from January-December 2010.. Positives for methamphetamine use in the U.S. general workforce dropped dramatically from 0.18% in 2006 to 0.11% in 2008. However, the rate remained the same in 2009 and 2010 at 0.10%.. Dr. Steven Shoptaw, a researcher who studies therapies for methamphetamine dependence, says, Ive worked with patients who, paralyzed by the recession and juggling multiple jobs and family responsibilities, started using methamphetamine for its functional stimulant benefit.. Shoptaw notes that, even when its used as a stimulant by people who work more than one job, meth can wreak havoc on their judgment.. For these sort of people, we now provide ...
Perspectives on drugs: health and social responses for methamphetamine users in Europe | www.emcdda.europa.eu
Although at low levels, methamphetamine is being used by diverse groups of drug users in different ways, and this is clearly raising a variety of challenges and initial responses from service providers. Services currently identified as responding to problems include mental health, low-threshold, drug treatment, youth and sexual health.. Methamphetamine has long been used by problem drug users in both the Czech Republic and Slovakia, with injection as the most common route of administration. In the Czech Republic mental health care and residential treatment programmes applying the therapeutic community model have been at the centre of the response (Kalina, 2007). The focus has been on client assessment, the use of psychosocial interventions and medical treatment, and social reintegration initiatives. Services offering information, including harm reduction advice to methamphetamine users, are also available. An innovative intervention has involved the distribution of empty gelatine capsules by ...
Neurotoxic effects of methamphetamine<...
TY - JOUR. T1 - Neurotoxic effects of methamphetamine. AU - Thrash, Bessy. AU - Karuppagounder, Senthilkumar S.. AU - Uthayathas, Subramaniam. AU - Suppiramaniam, Vishnu. AU - Dhanasekaran, Muralikrishnan. PY - 2010/1/1. Y1 - 2010/1/1. N2 - In Parkinsons disease, depletion of dopamine in the striatum leads to various symptoms such as tremor, rigidity and akinesia. Methamphetamine use has significantly increased in USA and around the world and there are several reports showing that its long-term use increases the risk for dopamine depletion. However, the toxic mechanisms of methamphetamine are not well understood. This study was undertaken to gain greater mechanistic understanding of the toxicity induced by methamphetamine. We evaluated the effect of methamphetamine on the generation of reactive oxygen species, mitochondrial monoamine oxidase, complex I & IV activities. Behavioral analysis evaluated the effect on catalepsy, akinesia and swim score. Neurotransmitter levels were evaluated using ...
Prenatal Methamphetamine Exposure and Childhood Behavior Problems at 3 and 5 Years of Age
From Pediatrics: OBJECTIVE: We evaluated behavior problems in children who were prenatally exposed to methamphetamine (MA) at ages 3 and 5 years. METHODS: The Infant Development, Environment, and Lifestyle study, a prospective, longitudinal study of prenatal MA exposure and child outcome, enrolled subjects postpartum in Los Angeles, California; Honolulu, Hawaii; Des Moines, Iowa; and Tulsa, Oklahoma. Prenatal…
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In the study published in Addiction Biology, researchers from three Taiwanese institutions explored the potential role of declining levels of a protein called BDNF in promoting the brain damage found in chronic methamphetamine abusers and addicts. Under normal circumstances, BDNF provides the brain with critical protection by helping nerve cells grow, reach maturity and stay in good working order. In addition, the protein plays an essential role in basic brain functionality by supporting the chemical and physical adaptations required for learning new information and storing that information in memory.. For their study, the researchers recruited 59 people diagnosed with methamphetamine abuse, as well as a second group of 59 generally healthy individuals who did not use the drug. The methamphetamine abusers had stopped actively taking the drug and were in the early stages of withdrawal. Over a period of three weeks, the researchers used blood tests to measure the levels of BDNF in both groups of ...
Long-term consequenses of methamphetamine exposure in young adults are exacerbated in glial cell line-derived neurotrophic...
Methamphetamine abuse in young adults has long-term deleterious effects on brain function that are associated with damage to monoaminergic neurons. Administration of glial cell line-derived neurotrophic factor (GDNF) protects dopamine neurons from the toxic effects of methamphetamine in animal models. Therefore, we hypothesized that a partial GDNF gene deletion would increase the susceptibility of mice to methamphetamine neurotoxicity during young adulthood and possibly increase age-related deterioration of behavior and dopamine function. Two weeks after a methamphetamine binge (4x10 mg/kg, i.p., at 2 h intervals), GDNF+/- mice had a significantly greater reduction of tyrosine hydroxylase immunoreactivity in the medial striatum, a proportionally greater depletion of dopamine and 3,4-dihydroxyphenylacetic acid (DOPAC) levels in the striatum, and a greater increase in activated microglia in the substantia nigra than wild-type mice. At 12 months of age, methamphetamine-treated GDNF+/-mice exhibited ...
High rates of dental and gum disease occur among methamphetamine users | National Institute on Drug Abuse (NIDA)
A new study funded by the National Institute on Drug Abuse (NIDA) documents the high rates and unique patterns of dental decay and gum disease in people who use the illicit drug methamphetamine. The large study of 571 methamphetamine users found that 96 percent had experienced dental cavities and 58 percent had untreated tooth decay. Only 23 percent retained all of their natural teeth, compared to a tooth retention rate of 48 percent among the U.S. general population. The study was conducted by investigators at the University of California, Los Angeles (UCLA).. The study found that adults reporting moderate or heavy methamphetamine use were twice as likely to have untreated dental cavities than were light users (less than 10 days of use over the past month). Older subjects (ages 30+), women, and current cigarette smokers were disproportionately affected by dental and periodontal disease. In addition, a significant percentage of participants (40 percent) indicated they were often self-conscious ...
Linkage disequilibrium and association with methamphetamine dependence/psychosis of μ-opioid receptor gene polymorphisms<...
TY - JOUR. T1 - Linkage disequilibrium and association with methamphetamine dependence/psychosis of μ-opioid receptor gene polymorphisms. AU - Ide, S.. AU - Kobayashi, H.. AU - Ujike, H.. AU - Ozaki, N.. AU - Sekine, Y.. AU - Inada, T.. AU - Harano, M.. AU - Komiyama, T.. AU - Yamada, M.. AU - Iyo, M.. AU - Iwata, N.. AU - Tanaka, K.. AU - Shen, H.. AU - Iwahashi, K.. AU - Itokawa, M.. AU - Minami, M.. AU - Satoh, M.. AU - Ikeda, K.. AU - Sora, Ide. N1 - Funding Information: We are grateful to the Japanese Ministry of Health, Labour and Welfare (MHLW) as well as to the Japanese Ministry of Education, Culture, Sports, Science and Technology (MEXT) for support in part by Grants MHLW13-040, MHLW15-7, MHLW17-pharmaco-001, MEXT15025206 and MEXT15029204.. PY - 2006/5. Y1 - 2006/5. N2 - Several studies indicate that the μ-opioid receptor plays a role in addiction not only to opiate drugs but also to alcohol and non-opiate addictive drugs. Our studies aim to reveal the associations between gene ...
Man from Albuquerque Sentenced to 30 Years in Federal Prison for Methamphetamine Trafficking | Bureau of Alcohol, Tobacco,...
ALBUQUERQUE, N.M. - Gaspar Leal, 49, of Albuquerque, New Mexico was sentenced yesterday in federal court in Albuquerque to 30 years (360 months) in prison after juries found him guilty of conspiracy to distribute methamphetamine at two separate trials.. On July 12, 2016, a grand jury returned an indictment charging Leal and two others with conspiracy to distribute and distribution of 50 grams or more of methamphetamine on June 8, 2016. On Dec. 6, 2017, a jury returned a verdict finding Leal guilty of conspiracy and not guilty of distribution. Two co-defendants pleaded guilty in this case. Candace Tapia, 24, of Albuquerque received a sentence of 18 months in prison for distribution of methamphetamine and Bernadette Aurora Tapia, 51, of Albuquerque received a sentence of 21 months in prison for conspiracy to distribute methamphetamine.. On Dec. 20, 2017, a grand jury returned a separate indictment charging Leal with conspiracy to distribute 50 grams or more of methamphetamine between July 21, ...
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Oklahoma Methamphetamine Prevention Initiative. :: Documents.OK.Gov
Four of the counties have been through the SPF and have selected evidence-based programs to implement in their county. The counties are implementing Too Good for Drugs, Project Alertand Creating Lasting Family Connections. For all of these programs, the NOMs survey will be used to evaluate overall effectiveness of the intervention. These counties have also chosen to implement a media campaign in order to create a comprehensive prevention approach using multiple strategies. Oklahoma Methamphetamine Prevention Initiative v Results The Oklahoma Prevention of Methamphetamine Abuse Initiative began in October of 2006 and is funded through a grant by the Substance Abuse and Mental Health Services Administration, Center for Substance Abuse Prevention. This initiative addresses the growing problem of methamphetamine abuse and addiction in Oklahoma. The goals of the project are to: 1. Reduce the incidence and prevalence of methamphetamine abuse and addiction through conducting community-based prevention ...
Methamphetamine and amphetamine concentrations in postmortem rabbit tissues<...
TY - JOUR. T1 - Methamphetamine and amphetamine concentrations in postmortem rabbit tissues. AU - Nagata, T.. AU - Kimura, K.. AU - Hara, K.. AU - Kudo, K.. PY - 1990/11. Y1 - 1990/11. N2 - The feasibility of detecting methamphetamine and its major metabolite, amphetamine, in postmortem tissues over a 2-year period was examined. It is important to determine if the abuse and toxic effects of drugs can be proved from evidence found in decayed, submerged, or stained tissue materials. The blood, urine, liver, skeletal muscle, skin and extremity bones from rabbits given methamphetamine intravenously were kept at room temperature, under 4 different conditions: sealed in a test tube, dried in the open air, submerged in tap water and stained on gauze. Methamphetamine was present in all the samples, with slight change in concentration in case of sealed and air dried tissues. Changes varied in bones kept in water. There were considerable decreases in methamphetamine in blood and urine stains. Despite long ...
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Methamphetamine | National Institute on Drug Abuse (NIDA)
Brief Description Methamphetamine is a stimulant drug usually used as a white, bitter-tasting powder or a pill. Crystal methamphetamine is a form of the drug that looks like glass fragments or shiny, bluish-white rocks. It is chemically similar to amphetamine [a drug used to treat attention-deficit hyperactivity disorder (ADHD) and narcolepsy, a sleep disorder]. Read the DrugFacts Learn more: Research Report on Methamphetamine Health Effects of Methamphetamine
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Progress in Understanding Basal Ganglia Dysfunction as a Common Target for Methamphetamine Abuse and HIV-1 Neurodegeneration |...
Title: Progress in Understanding Basal Ganglia Dysfunction as a Common Target for Methamphetamine Abuse and HIV-1 Neurodegeneration. VOLUME: 5 ISSUE: 3. Author(s):Shaji Theodore, Wayne A. Cass, Avindra Nath and William F. Maragos. Affiliation:Department of Neurology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama, Birmingham 1719, 6th Avenue South, CIRC 516, Birmingham, AL-35294, USA.. Keywords:Drug abuse, AIDS, glia, cytokines, dopamine, striatum, neurodegeneration. Abstract: HIV-1 infection with concurrent methamphetamine (MA) abuse results in exacerbated neurodegenerative changes and rapid progression of a form of sub-cortical dementia termed HIV-1 associated dementia (HAD). A notable feature of HAD is the involvement of the dopaminergic system manifested as parkinsonian like movement abnormalities. The HIV-1 transactivator of transcription (Tat) protein is very often used in experimental studies trying to understand neurotoxic consequences of HIV-1 ...
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Methamphetamine, frequently referred to as meth, is a highly-addictive neurotoxic stimulant that is commonly referred to as the most dangerous medicine in the world, due to the broad accessibility, simplicity of usage, and capability to make the drug from ordinary home items. Frequently, methamphetamine comes in two forms, Crystal Meth as well as powdered meth, both create similar impacts on the customer.. Meth generates an incorrect sense of well-being as well as joy. It provides the customer a rush, as well as a boost in sensations of power, confidence, and also wakefulness. These effects typically last 6 to 8 hours, however can be sustained for upwards of twelve hours.. Methamphetamine is merely as well as cheaply used different household products in regarding 2 days- start to end up. The vital active ingredient in methamphetamine is pseudoephedrine or ephedrine, both which are found in a wide variety of non-prescription chilly treatments.. ...
A Study of Impurities Found in Methamphetamine Synthesized From Ephedrine
Allen and Kiser considered the stereochemistry, mechanism and by-products which result from the conversion of ephedrine to methamphetamine . In that process, ephedrine is converted to its chloro analog followed by catalytic reduction to methamphetamine, Fig. 1 (route I). In the present article, we discuss the conversion of ephedrine to methamphetamine via hydriodic acid reduction (route II). The chemistry involved in route II was advanced by information gathered from Allen and Kisers article.. Illustration of the commonality of these syntheses is seen in the following facts. Stereochemistry implicit in the first route I also applies with hydriodic acid/red phosphorus reduction. That is, only (-)ephedrine and (+)pseudoephedrine yield (+)methamphetamine. Furthermore, the intermediate in route I (chloroephedrine from ephedrine with thionyl chloride) is a halo analog, and such is the case in route II. Ephedrine reacted with HI initially creates iodoephedrine in situ. Finally, the by-products of ...
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City-Centers urges everyone to visit MontanaMeth.org and/or http://www.notevenonce.com/ and to tell everyone you know to visit! Missouri Web Portal To Methamphetamine - GET EDUCATED NOW - GET YOUR CHILDREN EDUCATED! Methamphetamine is not just the a meth addicts problem, it is a Missouri and all of our problem! Methamphetamine is not just a problem in your state, it is a problem in the city where you live and in every city across America. Education is the only solution to the growing Methamphetamine problem in this country. GET EDUCATED NOW - GET YOUR CHILDREN EDUCATED!
Deputies Arrest Three for Trafficking Methamphetamine... - Press Releases - Cherokee County Sheriff AL
According to Cherokee County Sheriff Jeff Shaver, three suspects were arrested on U.S. Highway 411 just north of Centre on Tuesday, October 24, 2017, afternoon for trafficking methamphetamine. Sgt. Gene Knowles, assisted by Investigator Jeremy Stepps, stopped a vehicle for a traffic violation. The deputies located a large amount of methamphetamine and a handgun inside the vehicle and took three suspects into custody. Jacob C. Hill, 28, of New Hope and Keondrick I. Patterson, 20, of Huntsville were both charged with trafficking methamphetamine, unlawful possession of a controlled substance, and certain persons prohibited to possess a pistol. Katherine Antenor, 20, of Huntsville was charged with trafficking methamphetamine, unlawful possession of a controlled substance, and carrying a pistol without a permit. Deputies later learned two of the suspects are currently on bond from Madison County, Patterson for attempted murder and Hill for drug trafficking. Sheriff Shaver said the arrests were made ...
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Research Festival | Intramural Research Program | National Institutes of Health
Repeated administration of high doses of methamphetamine induces dopaminergic degeneration and reduction in locomotor activity. The purpose of this study was to examine the role of endogenous peroxisome proliferator-activated receptor gamma (PPARr) in protecting against methamphetamine toxicity. Adeno-associated virus (AAV) encoding the Cre recombinase gene was injected into the left substantia nigra of loxP-PPARr or wild type mice. Animals were treated with high doses of methamphetamine 1-month after viral injection. Administration of AAV-Cre selectively removed PPARr in left nigra in loxP-PPARr mice but not in the wild type mice. The loxP-PPARr/AAV-Cre mice that received methamphetamine showed a significant reduction in rotarod time. In vivo voltammetry was used to examine dopamine release/clearance and at 2 months after methamphetamine injection. The peak of dopamine release induced by local application of KCl and the rate of dopamine clearance were significantly attenuated in the left ...
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You let it sit for forty-five days without touching it. New York: Cambridge University Press; Our investigation into cold cook methods of producing methamphetamine emerged from an ethnographic study on suburban methamphetamine use.. Official decisions on policy and public health are influenced when facts are labelled as myths, which could result in adverse health repercussions for those affected by such decisions. However, one respondent who was recently introduced to methamphetamine in the suburbs described a noteworthy variation: Looks like little ice crystals…on a mop head. The meth cook extracts ingredients from those pills and to increase its strength combines the substance with chemicals such as battery acid, drain cleaner.. Because lab operators almost always illegally dump this waste in ways that damage the environment, national parks and other nature preserves and parks have been adversely affected. Dismantling the La Familia cartel, once the top meth producer, methamphtamine ...
What You Need to Know About Drugs: Methamphetamines
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Methamphetamine</span></span> <i class=x-anchor-sub-indicator aria-hidden=true data-x-icon-s= ></i> <span class=...
Currently, most methamphetamine in the United States is produced by transactional criminal organizations (TCOs) in Mexico. This methamphetamine is highly pure, potent, and low in price. The drug can be easily made in small clandestine laboratories, with relatively inexpensive over-the-counter ingredients such as pseudoephedrine, a common ingredient in cold medications. To curb this kind of production, the law requires pharmacies and other retail stores to keep a purchase record of products containing pseudoephedrine, and take steps to limit sales.. Methamphetamine production also involves a number of other very dangerous chemicals. Toxic effects from these chemicals can remain in the environment long after the lab has been shut down, causing a wide range of health problems for people living in the area. These chemicals can also result in deadly lab explosions and house fires.. ...
Alleged Members of Grant County Methamphetamine Trafficking Ring Arrested on Federal Charges | USAO-NM | Department of Justice
ALBUQUERQUE - Twelve individuals are facing methamphetamine trafficking charges as the result of a DEA-led investigation targeting a methamphetamine trafficking ring operating in Grant County, N.M. The 13-month investigation culminated this morning when all 12 defendants were arrested during an early morning law enforcement operation. The charges were announced by U.S. Attorney Damon P. Martinez, Special Agent in Charge Will R. Glaspy of the DEAs El Paso Division, Special Agent in Charge Waldemar Rodriguez of HSIs El Paso Division, and Special Agent in Charge Carol K.O. Lee of the FBIs Albuquerque Division.. The charges against the defendants are the result of an investigation that began in March 2014, and targeted a drug trafficking organization allegedly led by Daniel Lee Jacquez, 33, of Silver City, N.M., that distributed methamphetamine in Grant County, N.M. The investigation was designated as part of the Organized Crime Drug Enforcement Task Force (OCDETF) program, a nationwide ...
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Methamphetamine. Main article: Methamphetamine. Methamphetamine (contracted from N-methyl-alpha-methylphenethylamine) is ... Methamphetamine is known to have a high potential for abuse and addiction. Recreational use of methamphetamine may ... "Methamphetamine facts". DrugPolicy.org. Archived from the original on 17 April 2018. Retrieved 7 January 2014.. ... Methamphetamine may be sold illicitly, either as pure dextromethamphetamine or in an equal parts mixture of the right- and left ...
Methamphetamine. Talent cosponsored the Combat Meth Act with Sen. Dianne Feinstein (D-CA). The legislation, which was ...
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Methamphetamine production. After the fall of the Amezcua brothers - founders of the Colima Cartel - in 1999 on methamphetamine ... Guzmán oversaw operations whereby mass cocaine, methamphetamine, marijuana, and heroin were produced, smuggled into, and ... Until this point, the Sinaloa Cartel had been a joint venture between Guzmán and Ismael Zambada García; the methamphetamine ... Importantly, for the first time, the Colombians would not have to be paid - they simply joined methamphetamine with cocaine ...
Methamphetamine. Following the death of Congressman Charlie Norwood (R-GA) in February, 2007, Simpson has become a ... The advocacy inspired Simpson to introduce legislation regarding methamphetamine, specifically how the drug affects tooth decay ... with the purpose to understand and address the oral health problems associated with methamphetamine. The bill's goals are to ...
Methamphetamine. Prenatal methamphetamine exposure has shown to negatively impact brain development and behavioral ... This study had two groups, one containing children who were prenatally exposed to methamphetamine but no other illicit drugs ... The study results also suggest that prenatal exposure to methamphetamine may negatively impact processing speed as children ... A 2019 study further investigated neurocognitive and neurodevelopmental effects of prenatal methamphetamine exposure. ...
In 1893, Methamphetamine was first synthesised from ephedrine by Nagayoshi Nagai and in 1919, Akira Ogata was the first to ... Ogata's synthesis of methamphetamine replaced much more complicated earlier syntheses, and continues to be used as the basis ... Hillstrom, Kevin (2015). Methamphetamine. Farmington Hills, MI: Greenhaven Publishing LLC. p. 9. ISBN 978-1-4205-0872-7. Elaine ... was a Japanese chemist and the first to synthesize methamphetamine in crystalline form in 1919. In 1912, Ogata graduated from ...
"Methamphetamine , InfoFacts , The National Institute on Drug Abuse (NIDA)". Archived from the original on 28 September 2011. ... Dopaminergic stimulants like amphetamine, methamphetamine, cocaine, MDMA, and methylphenidate are euphoriants. Nicotine is a ...
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Methamphetamine is known to have a high potential for abuse and addiction. Recreational use of methamphetamine may result in ... Methamphetamine may be sold illicitly, either as pure dextromethamphetamine or in an equal parts mixture of the right- and left ... Recreationally, methamphetamine is used to increase sexual desire, lift the mood, and increase energy, allowing some users to ... Abuse of methamphetamine produces similar effects as well as marked degeneration of dopaminergic neurons, resulting in an ...
"Treatment & Management". Methamphetamine Toxicity. Medscape. WebMD. Archived from the original on April 9, 2016. Retrieved ... has not been reported with the use of beta blockers for treatment of methamphetamine toxicity. Other appropriate ... penetration such as metoprolol and labetalol may be useful for treating CNS and cardiovascular toxicity from a methamphetamine ... blocker labetalol is especially useful for treatment of concomitant tachycardia and hypertension induced by methamphetamine. ...
Risk factors of schizophrenia
Methamphetamine, a potent neurotoxic amphetamine derivative, induces psychosis in a substantial minority of regular users which ... March 2012). "Methamphetamine-associated psychosis". J Neuroimmune Pharmacol. 7 (1): 113-139. doi:10.1007/s11481-011-9288-1. ... Individuals who develop a long lasting psychosis, despite abstinence from methamphetamine, more commonly have a family history ...
"Methamphetamine (And Amphetamine)". Archived from the original on 31 October 2011. Retrieved 1 November 2011. Sulzer D, Chen TK ...
Those who have had a short-lived psychosis from methamphetamine can have a relapse of the methamphetamine psychosis years later ... Individuals who have a long history of methamphetamine use and who have experienced psychosis in the past from methamphetamine ... Methamphetamine induces a psychosis in 26-46 percent of heavy users. Some of these people develop a long-lasting psychosis that ... Methamphetamine-induced psychosis is likely gated by genetic vulnerability, which can produce long-term changes in brain ...
Capital punishment in Singapore
Methamphetamine (§6, (5)). Under the Act: any person who is proved to have had in his possession or custody or under his ... 250 grams of methamphetamine (§5 and §7, (9)(b)). Death sentences are also mandatory for any person caught manufacturing: ...
Most was methamphetamine; they also seized 3,750 liters (990 gallons) of liquid methylfentanyl that can be used to manufacture ...
Illegal drug trade
Methamphetamine is sometimes used intravenously, placing users and their partners at risk for transmission of HIV and hepatitis ... During this period, methamphetamine lab incidents increased in mid-western States (Illinois, Michigan, Missouri, and Ohio), and ... This method is reported to give "an unnatural high" and a "brief intense rush". In South Africa methamphetamine is called "tik ... I talian Police Make Major Heroin Haul On Ship From Iran Street Terms: Methamphetamine Office of National Drug Control Policy ...
F14.5 cocaine F15.5 other stimulants: amphetamines;[pages needed] methamphetamine; methylphenidate. See also stimulant ...
List of dopaminergic drugs
Methamphetamine (desoxyephedrine, methedrine; dextromethamphetamine, levomethamphetamine) • Methcathinone (methylpropion) • ...
Median lethal dose
Kiyatkin, Eugene A.; Sharma, Hari S. (2009). "Acute Methamphetamine Intoxication". New Concepts of Psychostimulant Induced ...
What is methamphetamine? Revised May 2019. Oct. 29, 2019 MDR Mitteldeutsches Fernsehen. Kokain des Ostens - Crystal Meth in ...
Attention deficit hyperactivity disorder management
The body metabolizes methamphetamine into amphetamine (in addition to less active metabolites). A quarter of methamphetamine ... "Methamphetamine and Amphetamine Pharmacokinetics in Oral Fluid and Plasma after Controlled Oral Methamphetamine Administration ... "methamphetamine (Rx) - Desoxyn". Medscape Drugs & Diseases. "methylphenidate (Rx) - Ritalin, Ritalin SR". Medscape Drugs & ... 2003). "Neurochemical and Behavioral Differences Between D-Methamphetamine and D-Amphetamine in Rats". Psychopharmacology. 165 ...
"Information Bulletin: Crystal Methamphetamine". www.justice.gov. Retrieved 20 January 2018. DeLeon-Rodriguez N, Lathem TL, ... It is sometimes used as a cutting agent for illicitly manufactured methamphetamine. It is also commonly found in the atmosphere ...
Hamamoto, DT; Rhodus, NL (January 2009). "Methamphetamine abuse and dentistry". Oral Diseases. 15 (1): 27-37. doi:10.1111/j. ... a condition potentially associated with long term methamphetamine use. Wassell R, Naru A, Steele J, Nohl F (2008). Applied ...
List of drugs by year of discovery
"Historical overview of methamphetamine". Vermont Department of Health. Government of Vermont. Archived from the original on 5 ... Shortly after amphetamine, methamphetamine was synthesized from ephedrine in 1893 by Japanese chemist Nagai Nagayoshi. Three ... Grobler SR, Chikte U, Westraat J (2011). "The pH Levels of Different Methamphetamine Drug Samples on the Street Market in Cape ... "Historical overview of methamphetamine". Vermont Department of Health. Retrieved 15 January 2012. CS1 maint: discouraged ...
List of Japanese inventions and discoveries
Methamphetamine Methamphetamine was first synthesized from ephedrine in Japan in 1894 by chemist Nagayoshi Nagai. In 1919, ... "Historical overview of methamphetamine". Vermont Department of Health. Retrieved 1 January 2012. Sakabe K, Okazaki R (December ... methamphetamine hydrochloride was synthesized by pharmacologist Akira Ogata. Nihonium Element 113. Named after Nihon, the local ...
... trifluoroacetylprolyl chloride allows for the detection of methamphetamine in urine. GC-MS of amphetamine and methamphetamine ... "Historical overview of methamphetamine". Vermont Department of Health. Government of Vermont. Archived from the original on 5 ... Outside Europe, the illicit market for amphetamine is much smaller than the market for methamphetamine and MDMA. As a result of ... Amphetamine and its derivatives like methamphetamine are weak base compounds that are the only widely used class of drugs known ...
"Methamphetamine and Benzodiazepines: Methamphetamine & Benzodiazepines". Erowid Experience Vaults. Retrieved 26 September 2006 ... or methamphetamine Used in treatment of organophosphate poisoning and reduces the risk of seizure induced brain and cardiac ...
Myanmar National Democratic Alliance Army
The area also produces methamphetamine. The MNDAA and other paramilitary groups control the cultivation areas, making them an ...
Richard Sanders (writer)
"Crystal Meth Facts - Methamphetamine Information". Chemistry.about.com. Retrieved 2011-01-13. "Google Health - Alcoholism". ... Sanders has written and spoken extensively about his own experiences with dropping LSD, injecting crystal methamphetamine and ...
Strawberry Quik meth myth
Crystal methamphetamine-based preparations may be colorless but flavored, may contain coloring but no flavoring, and may be ... It is also possible for poorly synthesized batches of methamphetamine to have a pink or very light reddish color. This is most ... Drug dealers were allegedly using coloring and flavoring to disguise methamphetamine as Strawberry Quik, thus making them more ... "Strategic Findings - National Methamphetamine Threat Assessment 2008 (UNCLASSIFIED)". Justice.gov. National Drug Intelligence ...
CMEA General Information
The Combat Methamphetamine Epidemic Act of 2005 (Title VII of the USA PATRIOT Improvement and Reauthorization Act of 2005, P.L ... General Information Regarding the Combat Methamphetamine Epidemic Act of 2005. [Title VII of Public Law 109-177]. Drug ... General Information Regarding the Combat Methamphetamine Epidemic Act of 2005 [Title VII of Public Law 109-177] PDF Version ... This document discusses those changes made by the Combat Methamphetamine Epidemic Act which primarily affect persons selling ...
Methamphetamine in Bangladesh - Wikipedia
Methamphetamine in Bangladesh is an illegal substance that is often consumed in the form of Yaba. Yaba is a drug made by ... "Inside Bangladeshs methamphetamine problem". Nikkei Asian Review. Retrieved 2018-05-30. "Bangladesh cricket player in police ... Drug gangs in Myanmar shifted from Heroin to Methamphetamine manufacturing in the late 1990s. Bangladesh shares a 250 ... combining methamphetamine and caffeine. They are sold as colorful pills. There are three forms of Yaba in Bangladesh, they are ...
Methamphetamine in the United States - Wikipedia
Mexican drug manufacturers began bringing methamphetamine north of the border, and forms of methamphetamine that could be ... Doses of 200 mg or more of methamphetamine are considered lethal. Symptoms of methamphetamine toxicity include difficulty ... p. 3. "A Brief History of Methamphetamine - Methamphetamine Prevention in Vermont". Vermont Department of Health. Archived from ... The crystalline form of methamphetamine contained at least 80 percent purity. The Illinois Methamphetamine Precursor Control ...
A famous experiment studied the effect of methamphetamine use on lab animals, who were given a dose of methamphetamine every ... Users who inject methamphetamine may damage their blood vessels, in addition to causing skin abscesses known as "speed bumps" ... Continued methamphetamine use can damage the brains ability to produce dopamine. Chronic use may also result in violent ... Methamphetamine has been known to cause premature osteoporosis, whereby teeth and bones become more brittle and prone to ...
Methamphetamine (also known as meth or crystal meth) is a very addictive drug. Read about the signs of meth addiction and ... Methamphetamine (Meth) (Nemours Foundation) Also in Spanish * Methamphetamine (Meth) (National Institute on Drug Abuse) Also in ... Methamphetamine Use and Oral Health (American Dental Association) - PDF * Methamphetamine Use and Pulmonary Hypertension ( ... Methamphetamine overdose (Medical Encyclopedia) Also in Spanish * Substance use -- amphetamines (Medical Encyclopedia) Also in ...
Prenatal methamphetamine exposure - Wikipedia
Prenatal methamphetamine exposure (PME) is the exposure of a fetus to methamphetamine when a woman uses the drug during her ... Methamphetamine (MA) has shown increasing popularity in the past two decades among women of childbearing age. Methamphetamine ... Methamphetamine is a highly addictive drug that can make users crave more as soon as the end of the last dose, which makes it ... Street methamphetamine is referred to by many names, such as "speed," "meth," and "chalk". The drug can be injected, smoked, ...
... is a amphetamines (CHEBI:35338) methamphetamine (CHEBI:6809) is a secondary amine (CHEBI:32863) ... methamphetamine (CHEBI:6809) has functional parent (S)-amphetamine (CHEBI:4469) methamphetamine (CHEBI:6809) has role central ... methamphetamine (CHEBI:6809) has role neurotoxin (CHEBI:50910) methamphetamine (CHEBI:6809) has role psychotropic drug (CHEBI: ... 4-hydroxymethamphetamine (CHEBI:76833) has functional parent methamphetamine (CHEBI:6809). methamphetamine(1+) (CHEBI:132297) ...
Methamphetamine - Multiple Languages: MedlinePlus
Category:Methamphetamine - Wikimedia Commons
Media in category "Methamphetamine". The following 95 files are in this category, out of 95 total. ... Methamphetamine-intoxication-in-a-dog-case-report-1746-6148-10-139-S1.ogv 9.0 s, 320 × 240; 186 KB. ... CBP Officers Seize $1.1 Million in Liquid Methamphetamine at Laredo Port of Entry (26241046741).jpg 3,600 × 3,968; 4.72 MB. ... Border Patrol Discovers Methamphetamine inside Cars Frame (21707796584).jpg 3,840 × 2,160; 2.26 MB. ...
Methamphetamine - Hawaii Drug Threat Assessment
Crystal Methamphetamine. Crystal methamphetamine is a colorless, odorless, smokable form of d-methamphetamine resembling glass ... Conversion to Crystal Methamphetamine. The conversion of powdered methamphetamine to crystal methamphetamine involves ... methamphetamine produced in Asia and locally produced methamphetamine also are available. Two types of methamphetamine are ... Autopsy Shows Man in Police Standoff Had Taken Crystal Methamphetamine. In January 2000 a crystal methamphetamine user held a ...
Blog Posts in Methamphetamine | RAND
Combat Methamphetamine Epidemic Act of 2005 - Wikipedia
The Combat Methamphetamine Epidemic Act of 2005 (CMEA) is federal legislation enacted in the United States on March 9, 2006, to ... Curbing Production of Methamphetamine Bill. Long title. An Act to further regulate and punish illicit conduct relating to ... It was argued that the CMEA would curtail the clandestine production of methamphetamine. The U.S. Department of Justice claims ... Combat Methamphetamine Epidemic Act of 2005. Other short titles. ... Methamphetamine Epidemic Elimination Act. Enacted by. the 109th ...
Methamphetamine use linked to heart condition | Reuters
Research suggests a link between a disease of the heart muscle called cardiomyopathy and use of methamphetamine -- a powerfully ... Methamphetamine use more than triples the risk of cardiomyopathy, report Dr. Khung-Keong Yeo of the University of California, ... A policeman guards bags of methamphetamine pills at a ceremony to destroy narcotics in Ayutthaya province, nearly 50 miles ... Research suggests a link between a disease of the heart muscle called cardiomyopathy and use of methamphetamine -- a powerfully ...
Filed Under: Crime & Courts, News Tagged With: Drugs, Methamphetamine. Methamphetamine makes a comeback with new baking methods ... You are here: Home / Archives for Methamphetamine. Manchester man sentenced to prison for making meth. August 4, 2015. By Dar ... The use of methamphetamine is falling in Iowa when compared to cocaine, but the number of meth lab busts is again on the rise. ... Filed Under: Crime & Courts, News Tagged With: Drugs, Methamphetamine. Men from Boone and Sioux City face prison time on meth ...
Which cutaneous findings suggest methamphetamine toxicity?
Drugs & Diseases , Emergency Medicine , Methamphetamine Toxicity Q&A Which cutaneous findings suggest methamphetamine toxicity? ... Evaluating the impact of community-based treatment options on methamphetamine use: findings from the Methamphetamine Treatment ... Characterizing methamphetamine withdrawal in recently abstinent methamphetamine users: a pilot field study. Am J Drug Alcohol ... Methamphetamine abuse and rhabdomyolysis in the ED: a 5-year study. Am J Emerg Med. 1999 Nov. 17(7):681-5. [Medline]. ...
National Methamphetamine Threat Assessment 2008 (UNCLASSIFIED)
Methamphetamine Prices by State and City--January Through June 2007. Preface. The National Methamphetamine Threat Assessment ... DEA - Ice methamphetamine. Inset photos from top:. Snohomish (Washington) Regional Task Force - Methamphetamine clandestine ... DEA - Ice methamphetamine crystals with pipe. Snohomish (Washington) Regional Drug Task Force - Methamphetamine clandestine ... Some methamphetamine produced in Canada is distributed in U.S. drug markets, including methamphetamine tablets sold as MDMA (3, ...
DEA - Publications - Methamphetamine Situation - Chemical Diversion
It generally is agreed that the most effective way of controlling the traffic in methamphetamine is to control the diversion of ... Other chemicals used in the manufacture of methamphetamine which are not under Federal regulation include iodine, used to make ... Traffickers from Mexico had established a virtually unlimited supply of chemicals for their clandestine methamphetamine ... provided law enforcement with an effective tool to attack the clandestine methamphetamine production problem. The CDTA imposed ...
Methamphetamine decontamination of houses
The director of Drug Screeners Ltd Shannon Balzat talks about the incidences of methamphetamine contamination and how easy it ... Methamphetamine decontamination of houses. From The Panel, 4:39 pm on 9 November 2015 ... The director of Drug Screeners Ltd Shannon Balzat talks about the incidences of methamphetamine contamination and how easy it ...
Methamphetamine and Parkinson's Disease
Methamphetamine is the second most widely used illicit drug in the world. In rodents, methamphetamine exposure damages ... Biochemical and neuroimaging studies in human methamphetamine users have shown decreased levels of dopamine and dopamine ... Consistent with these similarities, recent epidemiological studies have shown that methamphetamine users are almost twice as ... likely as non-users to develop PD, despite the fact that methamphetamine abuse and PD have distinct symptomatic profiles. ...
Methamphetamine -- Hazelden
... this is the definitive book about methamphetamines impact on individuals, communities, and sociaety. Meth ... The definitive book on the impact of methamphetamine on people, communities, and society, written by two of Americas leading ... Methamphetamine Its History, Pharmacology and Treatment Softcover, 296 pp. Item: 3923 Author: Ralph Weisheit, Ph.D.. Author: ... In Methamphetamine: Its History, Pharmacology, and Treatment, the first book in Hazeldens Library of Addictive Drugs series, ...
Methamphetamine lab busted in Framingham
Police last week made their first crystal methamphetamine lab bust of the year in Massachusetts , as law enforcement in New ... Methamphetamine lab busted in Framingham Share this:. *Click to share on Facebook (Opens in new window) ... Police last week made their first crystal methamphetamine lab bust of the year in Massachusetts , as law enforcement in New ...
Methamphetamine King [Explicit] - Ginger Bronson | Last.fm
Methamphetamine Facts | Drug Policy Alliance
Their chemical structures are similar, although the effect of methamphetamine on the central nervous system is more pronounced. ... The history of the use of methamphetamine is intertwined with the history of its chemical cousin amphetamine. ... Methamphetamine can be swallowed, snorted, smoked and injected by users. The effects usually last from four to eight hours or ... Nationally, methamphetamine use is not on the rise, though there are regional differences. The number of Americans who report ...
Desoxyn (Methamphetamine). *FDA approved for ADHD and Obesity. *Risk of diversion and misuse (crushed and snorted or injected) ... Most Methamphetamine users are white (0.7% of white population). *Pacific islanders (e.g. Hawaii) and Native Americans (2.2 to ... Yaba (Methamphetamine and Caffeine). *More common in southeast Asia, but growing use in the U.S. ... Methamphetamine Hydrochloride (crystalline). *High potency agent that is typically smoked. *Street Names: Crystal Meth, Glass, ...
... Topic Overview. Methamphetamine is a powerful stimulant. Its like amphetamine, which doctors use to treat ... Illegal methamphetamine is often made in makeshift laboratories from inexpensive ingredients.. Methamphetamine can be smoked, ... Methamphetamines high lasts from 8 to 24 hours. The drug can be detected in a urine drug screen up to 48 hours after use. ... Methamphetamine use can lead to stimulant use disorder. If use is stopped, it can lead to depression, anxiety, and paranoia. ...
Transcript: Combat Methamphetamine Epidemic Act (March 2017) | FDA
It can also be used illegally to produce methamphetamine - a powerful, highly addictive stimulant. FDA Drug Info Rounds ... It can also be used illegally to produce methamphetamine - a powerful, highly addictive stimulant. Im joined by Dr. Renu Lal ... CAPT Chew: The CMEA was enacted in an effort to combat illicit methamphetamine production while still permitting continued ... CAPT Chew: Administered by the Drug Enforcement Administration, the Combat Methamphetamine Epidemic Act of 2005, also known as ...
Neuroscience for Kids - Long Term Effects of Methamphetamine
Methamphetamine May Cause. Long-Lasting Brain Damage. May 5, 2000. It can be smoked, injected, or snorted.. It is known as ice ... Koch Crime Institute - Methamphetamine *clubdrugs.org GO TO:. Neuroscience In The News. Explore the Nervous System. Table of ... "It" is the drug called methamphetamine.. Areas of the basal ganglia examined.. A new study (Neurology, March 2000) by ... Compared to healthy people, methamphetamine abusers had reduced levels of NA in the basal ganglia and the white matter of the ...
MethAmphetamineAddictionProduction of methamphetamineAmount of MethamphetamineEffects of MethamphetaminePositive for methamphetamineConspiracy to distribute methamphetamineDesoxynDistribute methamphetamineABUSE2016DrugsAmphetaminesForm of methamphetamineDose of methamphetamineTons of MethamphetaminePounds of methamphetaminePossession of methamphetamineDistribution of methamphetamineSeizure2017Former methamphetamineDopamineClandestineCrystallineCombat Methamphetamine Epidemic ActChanges persist long after methamphetamineStimulant drugAbusersHeroinCentral nervous system sLaboratoriesSmall amounts of methamphetamineLong-term methamphetamineSearchPowerfully addictiveDependenceDrugYabaBags of methamphetamineEffect of methamphetamineSupply of methamphetamineSeizures of methamphetamineArrestsGramsNeuronsWithdrawalNeurotoxicityStimulantsLabsHuman methamphetamineProduce methamphetamineTransport methamphetamineManufacture methamphetamineToxicity
- Methamphetamine - meth for short - is a very addictive stimulant drug. (medlineplus.gov)
- Research suggests a link between a disease of the heart muscle called cardiomyopathy and use of methamphetamine -- a powerfully addictive illegal stimulant drug, also known as meth, crank, crystal, and speed. (reuters.com)
- Hydrochloride methamphetamine, known as "meth" or "speed", can be found in the powder state, compressed into tablets or capsules of 10 to 15 mg, or in a purer crystalline form. (hindawi.com)
- In recent years, the media have inundated us with coverage of the horrors that befall methamphetamine users, and the fires, explosions, and toxic waste created by meth labs that threaten the well-being of innocent people. (hazelden.org)
- In Methamphetamine: Its History, Pharmacology, and Treatment , the first book in Hazelden's Library of Addictive Drugs series, Ralph Weisheit and William L. White examine the nature and extent of meth use in the United States, from meth's early reputation as a "wonder drug" to the current perception that it is a "scourge" of society. (hazelden.org)
- The Voluntary Guidelines for Methamphetamine Laboratory Cleanup provides technical guidance for state and local personnel responsible for methamphetamine (meth) lab cleanup. (epa.gov)
- The Methamphetamine Remediation Research Act of 2007 (PDF) (56pp, 5.7M, About PDF ) required EPA to develop these guidelines, based on the best currently available knowledge in the field of meth lab remediation. (epa.gov)
- The guidelines are geared towards state and local government personnel charged with remediating or otherwise addressing former methamphetamine (meth) labs. (epa.gov)
- Although the prevalence of amphetamines, particularly methamphetamine (meth), has recently increased, meth is not nearly as much a part of the national discussion as cocaine, heroin, marijuana, and prescription-drug abuse are. (rand.org)
- In Thailand the use of methamphetamine has become a major public health issue, said Kelley, with signs that traffickers are pushing "promotional sales" of the more potent crystal meth to develop the market. (medindia.net)
- Methamphetamine (meth) is a prescription stimulant medication--synthesized from amphetamine--that is highly addictive, so its use in medical settings has declined. (soberrecovery.com)
- Methamphetamine (Meth) is an addictive stimulant that strongly activates certain systems in the brain. (smore.com)
- Methamphetamine ( methyl amphetamine or desoxyephedrine ), popularly shortened to meth and also nicknamed " ice " and Tina , is a psychostimulant and sympathomimetic drug . (bionity.com)
- It looks like white crystal and is known as crystal meth, meth, methamphetamine, methamphetamine crystal and so on. (hubpages.com)
- Methamphetamine (METH) is a highly addictive drug that is also neurotoxic to central dopamine (DA) systems. (nih.gov)
- Anhydrous ammonia is also a key ingredient for illicit methamphetamine (meth) production in makeshift laboratories. (cdc.gov)
- Methamphetamine (meth), a powerfully addictive stimulant, can be easily produced in illicit, makeshift laboratories and generally is considered the fastest-growing illicit drug in the United States (1). (cdc.gov)
- Methamphetamine (also called meth, crystal, chalk, and ice, among other terms) is an extremely addictive stimulant drug that is chemically similar to amphetamine. (streetdrugs.org)
- Long-term methamphetamine use has many negative consequences for physical health, including extreme weight loss, severe dental problems ("meth mouth"), and skin sores caused by scratching. (streetdrugs.org)
- Methamphetamine has been shown to have a higher affinity and, as a result, higher toxicity toward serotonergic neurons than amphetamine. (wikipedia.org)
- Methamphetamine belongs to the substituted phenethylamine and substituted amphetamine chemical classes. (wikipedia.org)
- Ephedrine, pseudoephedrine, and phenylpropanolamine are precursor chemicals used in the illicit manufacture of methamphetamine or amphetamine . (wikipedia.org)
- Association of Stimulant Use With Dopaminergic Alterations in Users of Cocaine, Amphetamine, or Methamphetamine: A Systematic Review and Meta-analysis. (medscape.com)
- The history of the use of methamphetamine is intertwined with the history of its chemical cousin amphetamine. (drugpolicy.org)
- Amphetamine was first synthesized in 1887, and methamphetamine was discovered in 1919. (drugpolicy.org)
- Following World War II, during which amphetamine was widely used to keep combat duty soldiers alert, both amphetamine (Adderall, Benzedrine, Dexidrine) and methamphetamine (Methedrine, Desoxyn) became more available to the public. (drugpolicy.org)
- In 1971, Congress passed the Comprehensive Drug Abuse Prevention and Control Act, which classified amphetamine and methamphetamine as Schedule II drugs, the most restricted category for prescription drugs. (drugpolicy.org)
- Like amphetamine, methamphetamine increases activity, decreases appetite and causes a general sense of well-being. (drugpolicy.org)
- Methamphetamine is a highly addictive psychostimulant drug that is chemically related to amphetamine. (medscape.com)
- In patients known to be hypersensitive to amphetamine, or other components of methamphetamine. (nih.gov)
- Methamphetamine is powerful stimulant drug, related to amphetamine, i.e. it speeds up the body's reactions and functions. (release.org.uk)
- Unlike amphetamine , methamphetamine is neurotoxic to human midbrain dopaminergic neurons . (wikipedia.org)
- People who abused methamphetamine or other amphetamine-like stimulants were more likely to develop Parkinson's disease than those who did not, in a new study from the Centre for Addiction and Mental Health (CAMH). (redorbit.com)
- Patients admitted to hospital for methamphetamine or amphetamine-use disorders had a 76 per cent higher risk of developing Parkinson's disease compared to those with no disorder. (redorbit.com)
- In total, 40,472 people, at least 30 years of age, had been hospitalized due to a methamphetamine- or amphetamine-use disorder during this period. (redorbit.com)
- Given that methamphetamine and other amphetamine stimulants are the second most widely used illicit drugs in the world, the current study will help us anticipate the full long-term medical consequences of such problematic drug use," said Dr. Callaghan. (redorbit.com)
- Methamphetamine is a prescription medication, synthesized from an amphetamine base and used primarily for treating Attention Deficit Hyperactivity Disorder (ADHD). (soberrecovery.com)
- Methamphetamine is known to possess a high addiction liability (i.e., a high likelihood that long-term or high dose use will lead to compulsive drug use) and high dependence liability (i.e. a high likelihood that withdrawal symptoms will occur when methamphetamine use ceases). (wikipedia.org)
- Methamphetamine hydrochloride dispensed in the United States is required to include a boxed warning regarding its potential for recreational misuse and addiction liability. (wikipedia.org)
- The definitive book on the impact of methamphetamine on people, communities, and society, written by two of America's leading addiction and criminal justice experts. (hazelden.org)
- Most people who use methamphetamine do not develop an addiction. (drugpolicy.org)
- For those individuals who do develop an addiction, treatment for methamphetamine addiction is similar to that for cocaine and other stimulants and just as likely to succeed. (drugpolicy.org)
- It has been a challenge to establish this link, because Parkinson's disease develops in middle and old age, and it is necessary to track a large number of people with methamphetamine addiction over a long time span. (redorbit.com)
- Methamphetamine is known to have a high potential for abuse and addiction. (smore.com)
- Methamphetamine addiction. (illinois.edu)
- Repeated methamphetamine abuse can also lead to addiction, which is accompanied by chemical and molecular changes in the brain. (smore.com)
- Methamphetamine abuse affects the human organism at many levels: brain, body, thoughts, genes… Our research allows deeper understanding of why and how methamphetamine addiction develops. (ohsu.edu)
- Anyone affected by methamphetamine addiction is urged to seek help through the Alcohol and Drug Helpline 0800 787797 or free text 1737 to speak with a trained counsellor. (scoop.co.nz)
- That very day a very bright engineering student who was an asset to our country all of a sudden due to methamphetamine addiction became liability upon his parents. (hubpages.com)
- What is the Cliffside Malibu methamphetamine addiction program and why do its patients succeed in kicking their addiction? (cliffsidemalibu.com)
- The experts at Cliffside Malibu understand the unique requirements for treating methamphetamine addiction and our program recognizes this: for example, the initial detox period at Cliffside may last for up to 30 days, ensuring the lingering chemical effects of the drug are purged completely from the body. (cliffsidemalibu.com)
- After medically supervised detox, our methamphetamine addiction program includes extended care and sober living sessions, with individual and group therapy sessions to address the physical and mental aspects of this particularly debilitating addiction. (cliffsidemalibu.com)
- Overcoming a methamphetamine addiction is a long and difficult battle, but Cliffside Malibu's staff has the experience and the commitment to help you win the battle, while our exclusive residence ensures privacy and the highest degree of comfort possible. (cliffsidemalibu.com)
- What can Cliffside Malibu do to help you beat your methamphetamine addiction? (cliffsidemalibu.com)
- they can even put you into immediate contact with an experienced therapist from our methamphetamine addiction program for advice over the telephone. (cliffsidemalibu.com)
- Repeated methamphetamine use can easily lead to addiction-a chronic, relapsing disease characterized by compulsive drug seeking and use. (streetdrugs.org)
- There is currently no effective treatment for methamphetamine addiction. (innovations-report.com)
- It is the only drug that has been shown to block any behavior associated with methamphetamine use, and is currently being tested by Catalyst Pharmaceutical Partners (http://www.catalystpharma.com/) for safety and efficacy against cocaine and methamphetamine addiction in humans in Phase II clinical trials across the U.S. (innovations-report.com)
Production of methamphetamine4
- It was argued that the CMEA would curtail the clandestine production of methamphetamine. (wikipedia.org)
- Methamphetamine use has stabilized nationally since 2002 after increasing during much of the 1990s, and domestic production of methamphetamine has decreased dramatically since 2004. (justice.gov)
- Working as partners, the York Regional Police and the York Region Health Services Substance Abuse Prevention Program jointly developed the York Region Methamphetamine Strategy to proactively address the production of methamphetamine and reduce its use within this region. (cmaj.ca)
- West Africa is believed to be a locus for production of methamphetamine that finds it way to Europe and to points abroad, and Nigerian gangs are thought to be heavily involved in the trade. (businessinsider.com)
Amount of Methamphetamine5
- Members of the task force, which is run by the sheriff's office, found a small amount of methamphetamine, as well as materials used to produce. (calcoastnews.com)
- Federal authorities in San Diego report a big increase in the amount of methamphetamine they seized along the border in fiscal 2010 compared with the previous year. (kpbs.org)
- U.S. border officials say the amount of methamphetamine seized at San Diego border crossings jumped 48 percent in fiscal 2010 compared with the previous year. (kpbs.org)
- Officials say the amount of methamphetamine they caught between the ports of entry also shot up, by 28 percent. (kpbs.org)
- Detectives searched the adjacent apartment and recovered a small amount of methamphetamine, an AK-47 assault rifle, two handguns and 5 gallons of a flammable solvent used to manufacture methamphetamine. (lapdonline.org)
Effects of Methamphetamine4
- The effects of methamphetamine abuse on Farrell's life are as painfully obvious as the burgundy scars lining her arms. (chicagotribune.com)
- What Are the Other Health Effects of Methamphetamine? (streetdrugs.org)
- Sarah's study was the first to show that oxytocin significantly reduced the rewarding effects of methamphetamine when locally administered into the nucleus accumbens core or subthalamic nucleus. (edu.au)
- This is the first research to show a functional role of oxytocin receptors in the region and provides insight into how oxytocin can reduce the rewarding effects of methamphetamine. (edu.au)
Positive for methamphetamine3
- Honolulu had the highest percentage of adult male arrestees who tested positive for methamphetamine among cities reporting to the Arrestee Drug Abuse Monitoring (ADAM) program in 2000. (justice.gov)
- FONTANA, Calif., July 13 (UPI) -- A California police department said a man was arrested on cruelty charges after his erratic-behaving chihuahua tested positive for methamphetamine. (upi.com)
- While the number of teens who have tried this deadly drug and the number of people testing positive for methamphetamine in the workplace have decreased in recent years, methamphetamine use is still a dangerous public health problem. (archives.gov)
Conspiracy to distribute methamphetamine3
- Forty-six-year-old Kurt Brookhart was sentenced to just over nine years in prison and 30-year-old Nahida Bucheit was sentenced to nearly six years in prison for conspiracy to distribute methamphetamine. (radioiowa.com)
- Bobek, 31, who won the U.S. figure skating title in 1995, was arrested at her home in Jupiter, Florida, last week on a charge of conspiracy to distribute methamphetamine in Hudson County, New Jersey, according to Guy Gregory of the Hudson County prosecutor's office. (cnn.com)
- On January 11, 2017, Tamasoa pled guilty to conspiracy to distribute methamphetamine and dealing firearms without a license. (dea.gov)
- Pharmaceutical methamphetamine is still available legally under the brand name Desoxyn, but only infrequently prescribed to treat severe obesity, narcolepsy and ADHD. (drugpolicy.org)
- Street gangs, local independent dealers, and outlaw motorcycle gangs (OMGs) distribute methamphetamine at the retail level. (justice.gov)
- The number of treatment admissions for methamphetamine abuse more than doubled from 1994 through 2000. (justice.gov)
- Violence associated with the distribution and abuse of methamphetamine is a serious concern for law enforcement officials and healthcare professionals in Hawaii. (justice.gov)
- Admissions to publicly funded treatment facilities for methamphetamine abuse are increasing in Hawaii. (justice.gov)
- According to TEDS, admissions for methamphetamine abuse increased overall from 644 in 1994 to 1,548 in 2000. (justice.gov)
- Those admitted to treatment for methamphetamine abuse accounted for 17.0 percent of all admissions in 1994 compared with 27.3 percent in 2000, when 73.8 percent were aged 21 to 40, and 8.5 percent were 17 or younger. (justice.gov)
- Lifetime methamphetamine abuse remained stable at low levels among the adult population in Hawaii from 1995 to 1998 but increased among young adult males. (justice.gov)
- According to the Center for Substance Abuse Treatment, during that timeframe the number of treatment admissions to publicly funded facilities for methamphetamine abuse increased among Caucasians, Japanese Americans, and Native Hawaiians, while the number of admissions decreased among Filipinos. (justice.gov)
- Less than 1 percent of all adult respondents in Hawaii reported lifetime methamphetamine abuse, according to the 1995 and 1998 Center for Substance Abuse Treatment surveys. (justice.gov)
- Data from ADAM indicate that methamphetamine abuse among adult male arrestees is a serious problem in Hawaii. (justice.gov)
- Despite the significance of the methamphetamine problem among the adult population, Hawaii school age youths have lower rates of lifetime methamphetamine abuse than youths nationwide. (justice.gov)
- According to the 2000 Hawaii Student Alcohol, Tobacco, and Other Drug Use Study, 2 percent of eighth grade, 5 percent of tenth grade, and 6 percent of twelfth grade students reported lifetime methamphetamine abuse. (justice.gov)
- According to the Hawaii study, 4 percent of eighth grade, 7 percent of tenth grade, and 8 percent of twelfth grade students nationwide reported lifetime methamphetamine abuse. (justice.gov)
- According to the 1999 Youth Risk Behavior Survey (YRBS), 7.7 percent of high school students in Hawaii reported lifetime methamphetamine abuse compared with 9.1 percent of high school students nationwide. (justice.gov)
- Due to budget concerns the federal government just shut down a critical data source that provides insights into abuse, dependence on, and spending on heroin and other hard drugs like crack and methamphetamine. (rand.org)
- A chart review of patients aged 45 and younger discharged from a medical center in Honolulu, Hawaii, with a diagnosis of cardiomyopathy or heart failure revealed a high prevalence of methamphetamine abuse in this population. (reuters.com)
- Methamphetamine abuse and emergency department utilization. (medscape.com)
- Consistent with these similarities, recent epidemiological studies have shown that methamphetamine users are almost twice as likely as non-users to develop PD, despite the fact that methamphetamine abuse and PD have distinct symptomatic profiles. (hindawi.com)
- Researchers do not yet know if the changes in brain chemistry caused by methamphetamine abuse are permanent or how these changes might affect behavior later in life. (washington.edu)
- [ 1 , 2 ] Fortunately, this trend seems to have reached a plateau in some areas, with the National Institute on Drug Abuse reporting that from 2015 to 2016, methamphetamine use in the past year by those 12 years of age and older decreased from 0.6% to 0.5% of the population. (medscape.com)
- Methamphetamine should not be given to patients who are in an agitated state or who have a history of drug abuse. (nih.gov)
- National Institute on Drug Abuse , , https://www.drugabuse.gov/drugs-abuse/methamphetamine. (drugabuse.gov)
- Methamphetamine abuse shatters families and threatens our communities. (archives.gov)
- On National Methamphetamine Awareness Day, we underscore the dangers of methamphetamine and reaffirm our collective responsibility to combat all forms of drug abuse. (archives.gov)
- My Administration is committed to fighting the spread of methamphetamine abuse throughout our country. (archives.gov)
- To help reach these objectives, my proposed 2007 budget includes $25 million to help ensure that Americans have access to effective methamphetamine abuse recovery services and programs. (archives.gov)
- To find out how to raise awareness and to learn more about the battle against methamphetamine abuse, concerned citizens may visit theantidrug.com and methresources.gov . (archives.gov)
- Illicit methamphetamine laboratories in the Delaware valley a report of the Select Committee on Narcotics Abuse and Control, Ninety-sixth Congress, second session. (illinois.edu)
- Some of these changes persist long after methamphetamine abuse is stopped. (smore.com)
- The Methamphetamine Abuse Research Center (MARC) at OHSU and the Portland VA Medical Center is a new NIDA center approaching drug research at all these levels, in a truly translational context. (ohsu.edu)
- Meet the Methamphetamine Abuse Research Center team and see an introduction to what we do. (ohsu.edu)
- But there is no way of knowing what the toll will be on her daughter, a bright-eyed, apparently healthy infant with a thick crown of dark hair born here in San Diego County, which has the highest rate of methamphetamine use in the country, according to the Maryland-based National Institute on Drug Abuse. (chicagotribune.com)
- Fifteen years after widespread cocaine abuse raised fears that a generation of so-called crack babies had suffered profound and possibly irreparable damage because they had been exposed to drugs in their mothers' wombs, the nation's changing drug abuse patterns are leading to similar concerns about methamphetamine. (chicagotribune.com)
- The federal drug abuse agenda, historically dominated by drugs that plague Eastern urban areas, was slow to address the emergence of methamphetamine, said Richard Rawson, associate director of the Integrated Substance Abuse Program at the University of California-Los Angeles School of Medicine. (chicagotribune.com)
- Drug Enforcement Agency: Domestic methamphetamine production, trafficking, and abuse are concentrated in the western, southwestern, and midwestern United States. (cdc.gov)
- Inasmuch as this association applies to methamphetamine (MA) abuse, an understanding of the course of MA withdrawal symptoms may help to direct treatment for MA dependence. (ingentaconnect.com)
- This initiative promotes the use and development of evidence-based and practice-based models that represent culturally-appropriate prevention and treatment approaches to methamphetamine abuse and suicide prevention from a community-driven context. (ihs.gov)
- Admissions to treatment for methamphetamine abuse more than double in the last 10 years. (stopaddiction.com)
- Uncovering the brain mechanisms of how oxytocin administration can reduce methamphetamine abuse provides future avenues for drug development. (edu.au)
- According to the National Institute on Drug Abuse, methamphetamine is a very addictive stimulant that is quickly becoming an American public health epidemic. (innovations-report.com)
- Aptamer-Based, Exonuclease-Amplified, Paper Device for Point of Collection Screening of Cocaine and Methamphetamine in Oral Fluid , NIJ-Sponsored, September 2016, NCJ 250564. (ncjrs.gov)
- A member of the Philippine National Police (PNP) shows confiscated methamphetamine, known locally as Shabu, seized from suspected drug pushers during an operation by the police in Quiapo city, metro Manila, Philippines July 3, 2016. (businessinsider.com)
- Certain illicit drugs, such as cocaine and methamphetamine, are restricted at both the federal and state level. (findlaw.com)
- Explanation of the illegality of growing or manufacturing illegal drugs, such as marijuana and methamphetamine. (findlaw.com)
- As with many other drugs including cocaine, methamphetamine works by releasing large amounts of dopamine into the section of the brain that controls the feeling of pleasure. (asu.edu)
- As with other addictive drugs, chronic use of methamphetamine can cause a tolerance to develop within the user. (asu.edu)
- Identification of impurities and statistical classification of methamphetamine hydrochloride drugs seized in China. (medscape.com)
- Methamphetamine production is a relatively simple process, especially when compared to many other recreational drugs. (drugpolicy.org)
- By studying trends of methamphetamine and other illicit drugs in communities in Canada and the United States, law enforcement professionals anticipate the use and production of the drug will increase in Ontario in coming years. (cmaj.ca)
- Globally, methamphetamine and similar stimulants are the second most commonly used class of illicit drugs. (redorbit.com)
- Last year 227 million methamphetamine pills were seized in East and Southeast Asia -- up 59 percent from the year before and a more than seven-fold increase compared with 2008, the United Nations Office on Drugs and Crime (UNODC) said. (medindia.net)
- A study published in CMAJ found that the use of crystal methamphetamine by street-involved youth is linked to an increased risk of injecting drugs. (medindia.net)
- Because the effects are long-lasting, overdose is most often treated with other drugs that counter the effects of the methamphetamine. (soberrecovery.com)
- Methamphetamine is also indicated as a short-term (i.e., a few weeks) treatment for obesity as an adjunct in a regimen of weight reduction based on caloric restriction, for patients in whom obesity is refractory to alternative therapy , e.g., repeated diets, group programs, and other drugs. (rxlist.com)
- What Other Drugs Interact with Methamphetamine? (rxlist.com)
- Methamphetamine has serious interactions with at least 36 different drugs. (rxlist.com)
- Methamphetamine has moderate interactions with at least 204 different drugs. (rxlist.com)
- A Texas grandfather was allegedly smuggling heroin, methamphetamine and other illegal drugs while crossing the U.S.-Mexico border in a taxi cab with his 6-year-old grandson. (chron.com)
- Results of a study by radiology professor Dr. Jody Tanabe, published in the journal Radiology July 14, showed that among people previously dependent on cocaine, amphetamines and/or methamphetamine, women showed significant loss of gray matter. (denverpost.com)
- Taking even small amounts of methamphetamine can result in many of the same physical effects as those of other stimulants, such as cocaine or amphetamines. (streetdrugs.org)
Form of methamphetamine3
- The illegal form of methamphetamine is a white, odorless, bitter-tasting, crystalline powder that can be dissolved easily in water or alcohol. (rexhealth.com)
- The smokable form of methamphetamine ("ice") produces an immediate euphoria similar to that of crack cocaine, but the effects may last much longer. (medscape.com)
- Crystalline methamphetamine is the purest form of methamphetamine available in Australia. (nsw.gov.au)
Dose of methamphetamine3
- A famous experiment studied the effect of methamphetamine use on lab animals, who were given a dose of methamphetamine every time they pushed a lever. (asu.edu)
- Do not use more than the recommended dose of methamphetamine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. (drugs.com)
- They pre-treated animals with vigabatrin two-and-a-half hours before giving them another priming dose of methamphetamine followed by free access to all three chambers. (innovations-report.com)
Tons of Methamphetamine1
- Mexican troops seized 15 tons of methamphetamine in a western state of Mexico, the Associated Press reported Thursday , which if sold in the U.S. would be worth $4 billion. (theatlantic.com)
Pounds of methamphetamine3
- A San Luis Obispo County deputy's investigative skills led to the arrest of a woman transporting 13 pounds of methamphetamine floating in her gas tank. (calcoastnews.com)
- An American woman was arrested walking across the Mexican border near El Paso with three pounds of methamphetamine hidden inside her underwear, officials said Friday. (chron.com)
- Detectives estimate the operation was capable of producing enough ephedrine to manufacture approximately 20 pounds of methamphetamine. (lapdonline.org)
Possession of methamphetamine5
- Internationally, the production, distribution, sale, and possession of methamphetamine is restricted or banned in many countries, due to its placement in schedule II of the United Nations Convention on Psychotropic Substances treaty. (wikipedia.org)
- The production, distribution, sale, and possession of methamphetamine is restricted or illegal in many jurisdictions. (smore.com)
- A 42-year-old local man was arrested and charged with possession of methamphetamine for supply. (scoop.co.nz)
- A 45-year-old Waitara man and 32-year-old Opunake woman have been charged with possession of methamphetamine. (scoop.co.nz)
- A traffic stop of a Lucia Mar Unified School District school bus on Thursday led to the arrest of the driver for possession of methamphetamine for sale. (calcoastnews.com)
Distribution of methamphetamine3
- Three men are facing prison time in two cases involving the distribution of methamphetamine. (radioiowa.com)
- The key criminal incentive to becoming involved in the production and distribution of methamphetamine is profit. (cmaj.ca)
- BOISE - Alfredo Esparza, Jr. of Nampa, Idaho, was sentenced in U.S. District Court to 60 months in prison for distribution of methamphetamine. (irs.gov)
- Within a month following enactment of the CDTA and the controls it placed upon ephedrine powder, the first encounter in the United States with ephedrine tablets at a clandestine methamphetamine laboratory seizure occurred. (fas.org)
- In severe overdoses, termination of methamphetamine-induced seizure activity and arrhythmias are of immediate importance. (medscape.com)
- MEXICO CITY - Mexican authorities announced their largest methamphetamine seizure ever late Wednesday: 15 tons, found in pure powder form at a ranch outside Guadalajara. (nytimes.com)
- They say it is the biggest methamphetamine seizure this year. (radionz.co.nz)
- Just Science Podcast: Special Release: Just One Pot Methamphetamine , NIJ-Sponsored, July 2017, NCJ 250949. (ncjrs.gov)
- On April 26, 2017, Malauulu was sentenced to 20 years in prison, and on May 17, 2017, Ortiz was sentenced to 10 years in prison for the methamphetamine trafficking activity. (dea.gov)
- Researchers used brain-imaging methods to compare chemicals in the brains of 26 former methamphetamine abusers and 24 healthy, age-matched people. (washington.edu)
- The Methamphetamine Remediation Research Act of 2007 required EPA to develop guidelines for remediating former methamphetamine labs. (epa.gov)
- This document provides those guidelines for States and local agencies to improve "our national understanding of identifying the point at which former methamphetamine laboratories become clean enough to inhabit again. (epa.gov)
- Adaptive changes in chemical activity in certain regions of the brain of former methamphetamine users who have not used the drug for a year or more suggest some recovery of neuronal structure and function, according to an article in the April issue of Archives of General Psychiatry . (news-medical.net)
- In fact, it is suggested that methamphetamine produces the equivalent of 600 times the normal amount of dopamine normally released by the brain during pleasurable events. (asu.edu)
- In addition to the pleasurable effects users may experience, methamphetamine has a number of other short-term effects and even a single high dose of the drug has been shown to damage nerve terminals in the dopamine-containing regions of the brain. (asu.edu)
- Continued methamphetamine use can damage the brain's ability to produce dopamine. (asu.edu)
- Methamphetamine (MA), a potent central nervous system stimulant, causes a rush of dopamine, norepinephrine, and serotonin release in the brain when ingested. (wikipedia.org)
- In rodents, methamphetamine exposure damages dopaminergic neurons in the substantia nigra, resulting in a significant loss of dopamine in the striatum. (hindawi.com)
- Biochemical and neuroimaging studies in human methamphetamine users have shown decreased levels of dopamine and dopamine transporter as well as prominent microglial activation in the striatum and other areas of the brain, changes similar to those observed in PD patients. (hindawi.com)
- Because animal studies have shown that methamphetamine damages dopamine-producing areas in the brain, scientists have worried that the same might happen in humans. (redorbit.com)
- Because cocaine is another type of stimulant that affects dopamine, this group could be used to determine whether the risk was specific to methamphetamine stimulants. (redorbit.com)
- Methamphetamine enters the brain and triggers a cascading release of norepinephrine , dopamine and serotonin . (bionity.com)
- Methamphetamine induces or stimulates our brain to release large amounts of dopamine which in turns makes us euphoric. (hubpages.com)
- Methamphetamine-induced neurotoxicity disrupts naturally occurring phasic dopamine signaling. (nih.gov)
- Methamphetamine increases the amount of the neurotransmitter dopamine, leading to high levels of that chemical in the brain. (streetdrugs.org)
- The amending of the Controlled Substances Act of 1970 (CSA) in 1988 to include the provisions of the Chemical Diversion and Trafficking Act (CDTA) provided law enforcement with an effective tool to attack the clandestine methamphetamine production problem. (fas.org)
- Traffickers and clandestine laboratory operators quickly discovered the ease with which ephedrine tablets could be converted to methamphetamine and began to take advantage of this loophole in the law. (fas.org)
- Information on children found at methamphetamine labs can be found in Children at Clandestine Metham. (ncjrs.gov)
- On March 29, 2001, Detectives assigned to the Narcotics Division, Clandestine Lab Squad received information regarding a possible methamphetamine producing laboratory in an apartment located on the 7500 block of Vineland Avenue in North Hollywood. (lapdonline.org)
- Methamphetamine is available in powder and crystalline forms. (medscape.com)
Combat Methamphetamine Epidemic Act5
- The Combat Methamphetamine Epidemic Act of 2005 ( Title VII of the USA PATRIOT Improvement and Reauthorization Act of 2005, P.L. 109-177 ) was signed into law March 9, 2006. (usdoj.gov)
- This document discusses those changes made by the Combat Methamphetamine Epidemic Act which primarily affect persons selling products containing the List I chemicals ephedrine, pseudoephedrine, and phenylpropanolamine. (usdoj.gov)
- Other actions taken by the Combat Methamphetamine Epidemic Act are not discussed here. (usdoj.gov)
- Administered by the Drug Enforcement Administration, the Combat Methamphetamine Epidemic Act of 2005, also known as the CMEA, sets legal requirements for the sale and purchase of certain nonprescription drug products. (fda.gov)
- Earlier this year, I also signed into law the Combat Methamphetamine Epidemic Act of 2005, which makes manufacturing the drug more difficult and imposes tougher penalties on those who smuggle or sell it. (archives.gov)
Changes persist long after methamphetamine1
- Some of these brain changes persist long after methamphetamine use is stopped, although some may reverse after being off the drug for a sustained period (e.g., more than 1 year). (streetdrugs.org)
- Abusers prefer high purity--averaging over 90 percent--crystal methamphetamine, which is smoked in glass pipes. (justice.gov)
- Methamphetamine is taken by abusers for several desired effects: euphoria and a sense of well-being, increased physical activity and energy, and decreased anxiety. (hindawi.com)
- Compared to healthy people, methamphetamine abusers had reduced levels of NA in the basal ganglia and the white matter of the frontal lobe. (washington.edu)
- Significant increases in these chemicals were found in the gray matter of the frontal lobes of methamphetamine abusers. (washington.edu)
- North American methamphetamine abusers are predominantly white males in their 30s and 40s. (medscape.com)
- Methamphetamine abusers can transform homes into places of danger and despair by neglecting or endangering the lives of their children, spouses, and other loved ones. (archives.gov)
- Drug gangs in Myanmar shifted from Heroin to Methamphetamine manufacturing in the late 1990s. (wikipedia.org)
- Although methamphetamine use is currently less prevalent than the use of marijuana, ecstasy, crack, cocaine and heroin across Canada, its low cost, easy availability and higher dependency levels have led health officials and police to prepare for the dangers that increased use could bring. (cmaj.ca)
- The purpose of this award is to support outstanding basic and/or clinical researchers with the vision and expertise to translate research discoveries into medications for the treatment of Substance Use Disorders (SUDs) stemming from tobacco, cannabis, cocaine, methamphetamine, heroin, or prescription opiate use. (medworm.com)
- There has been more research on the effects of alcohol, heroin and cocaine on the developing fetus than on methamphetamine, and no reliable estimate exists for the number of infants prenatally exposed to the drug. (chicagotribune.com)
Central nervous system s2
- Production workers in illicit methamphetamine laboratories may present with extensive thermal and/or chemical burns. (medscape.com)
- Illegal methamphetamine is often made in makeshift laboratories from inexpensive ingredients. (rexhealth.com)
- According to the Royal Canadian Mounted Police, between 1999 and 2004, the highest number of laboratories producing methamphetamine in Canada were located in British Columbia, followed by Alberta, Ontario, Quebec, Manitoba and Saskatchewan. (cmaj.ca)
- 1 Table 1 shows the number of identified and dismantled methamphetamine laboratories in Canada in 2005. (cmaj.ca)
- The experience of the police in the York Region, a jurisdiction of about 1 000 000 people in the Greater Toronto Area, puts the emerging societal impact of methamphetamine laboratories into perspective. (cmaj.ca)
- What harms exist for children found at methamphetamine laboratories? (ncjrs.gov)
- Detection of One Pot Methamphetamine Laboratories via Wastewater Sampling , NIJ-Sponsored, 2019, NCJ 254674. (ncjrs.gov)
- Illicit methamphetamine laboratories in the Delaware valley. (illinois.edu)
- Methamphetamine, which also goes by the street names "speed" and "crank", is an addictive stimulant often made in home laboratories. (bbc.com)
Small amounts of methamphetamine1
- In 2001, York Regional Police made 3 seizures of small amounts of methamphetamine that were intended for personal use. (cmaj.ca)
- Recent animal and human studies suggest that neuronal changes associated with long-term methamphetamine use may not be permanent but may partially recover with prolonged abstinence . (news-medical.net)
- A search on thomas.loc.gov turned up no pending legislation on methamphetamine proliferation , and of the two hits (hehe) relevant to drug policy turned up by a search on "methamphetamine" alone, neither contained the blatantly unconstitutional restrictions on speech found in the old MAPA. (everything2.com)
- A subsequent search of the suspect's vehicle uncovered chemicals used in the manufacture of methamphetamine. (lapdonline.org)
- Methamphetamine is a powerfully addictive drug that dramatically affects users' minds and bodies. (archives.gov)
- To put the study findings into numbers, if 10,000 people with methamphetamine dependence were followed over 10 years, 21 would develop Parkinson's, compared with 12 people out of 10,000 from the general population. (redorbit.com)
- Methamphetamine (MA) dependence is a source of continuing danger for both individuals and society. (clinicaltrials.gov)
- To date, there are no medications available to treatment methamphetamine dependence. (clinicaltrials.gov)
- Everyone will receive talk therapy for methamphetamine dependence. (clinicaltrials.gov)
- Methamphetamine (MA) dependence is a significant source of deleterious consequences to individual and public health including HIV infection, psychological distress, and cardiovascular disease. (clinicaltrials.gov)
- There are no current pharmacotherapies that have been approved by the Food and Drug Administration or the Therapeutic Goods Administration for methamphetamine dependence. (edu.au)
- Methamphetamine use in Australia and the associated social and economic burden means that an urgent treatment for reducing dependence is required. (edu.au)
- Users who inject methamphetamine may damage their blood vessels, in addition to causing skin abscesses known as "speed bumps" by accidentally injecting the drug under the skin. (asu.edu)
- Prenatal methamphetamine exposure (PME) is the exposure of a fetus to methamphetamine when a woman uses the drug during her pregnancy. (wikipedia.org)
- Methamphetamine is second only to cannabis as the most widely used illegal drug, which may be because it is relatively cheap and easy to manufacture. (wikipedia.org)
- Methamphetamine (contracted from N-methylamphetamine) is a potent central nervous system (CNS) stimulant that is mainly used as a recreational drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder and obesity. (wikipedia.org)
- While dextromethamphetamine is a more potent drug, racemic methamphetamine is sometimes illicitly produced due to the relative ease of synthesis and limited availability of chemical precursors. (wikipedia.org)
- As methamphetamine is associated with a high potential for misuse, the drug is regulated under the Controlled Substances Act and is listed under Schedule II in the United States. (wikipedia.org)
- Methamphetamine, particularly high purity crystal methamphetamine also known as ice, poses the greatest drug threat to Hawaii. (justice.gov)
- Mexican criminal groups transport crystal and powdered methamphetamine from the West Coast into Hawaii and distribute the drug at the wholesale level. (justice.gov)
- It discusses a wide range of issues, including methamphetamine production in Mexico, the increasing availability of Mexican ice methamphetamine in domestic drug markets, and apparent methamphetamine shortages in some western markets. (justice.gov)
- However, the increasing prevalence of high-purity ice methamphetamine throughout the country and the expansion of methamphetamine networks operated by Mexican and, more recently, Asian drug trafficking organizations (DTOs) have largely sustained methamphetamine markets in the United States. (justice.gov)
- Despite heightened chemical import restrictions in Mexico, methamphetamine production in that country has increased since 2004, and Mexico is now the primary source of methamphetamine to U.S. drug markets. (justice.gov)
- The director of Drug Screeners Ltd Shannon Balzat talks about the incidences of methamphetamine contamination and how easy it is to fool the drug detectors. (radionz.co.nz)
- Methamphetamine is the second most widely used illicit drug in the world. (hindawi.com)
- Thoroughly researched and highly readable, Methamphetamine offers a comprehensive understanding of medical, social, and political issues concerning this highly impactful drug. (hazelden.org)
- Written for professionals and serious lay readers by nationally recognized experts, Methamphetamine is a thoroughly researched and highly readable book on the medical, social, and political issues concerning this impactful drug. (hazelden.org)
- Yaba is a drug made by combining methamphetamine and caffeine. (wikipedia.org)
- Police last week made their first crystal methamphetamine lab bust of the year in Massachusetts , as law enforcement in New England continues its battle against the addictive drug. (bostonherald.com)
- Inadvertent absorption of methamphetamine may occur in "body packers", who swallow packages of the drug for transportation purposes, or "body stuffers", who insert bags of methamphetamine rectally or vaginally in an attempt to elude drug enforcement. (medscape.com)
- This includes methamphetamine seized from drug dealers associated with criminal organizations. (cmaj.ca)
- The York Region Methamphetamine Strategy is based on the 4-pillar approach of prevention, treatment, enforcement and harm reduction in A Framework for Action, A Four-Pillar Approach to Drug Problems in Vancouver . (cmaj.ca)
- According to the 2010 National Survey on Drug Use and Health, the number of Americans 12 and older who said they had used methamphetamine in the past 12 months declined 46 percent from 2002 to 2010, to 954,000 from an estimated 1.8 million. (nytimes.com)
- This article is about the free base and salts of methamphetamine, a recreational drug. (wikipedia.org)
- A new report into alcohol and drug use among police detainees shows a reduction in cannabis and alcohol consumption, while the demand for methamphetamine is on the rise. (nzherald.co.nz)
- The 2015 New Zealand Arrestee Drug Use Monitoring Programme Report reveals the proportion of detainees who felt dependent on methamphetamine increased from 20 per cent in 2011 to 35 per cent last year. (nzherald.co.nz)
- Significant increases in the use of methamphetamine were noted in Wellington and Christchurch, with over 40 per cent of detainees in Wellington Central watch houses having used the drug in the past year. (nzherald.co.nz)
- Crystal methamphetamine is a form of the drug that looks like glass fragments or shiny, bluish-white rocks. (drugabuse.gov)
- Explains to young teens how methamphetamine acts in the body and the brain and what happens with long-term use of the drug. (drugabuse.gov)
- New Zealand authorities say they believe they've disrupted a major international drug syndicate, after seizing up to $6 million worth of methamphetamine being smuggled into the country. (radionz.co.nz)
- A ustralian officials have seized the nation's largest haul of methamphetamine at the Melbourne waterfront in a shipment of almost 1.8 tons of the illicit drug hidden in stereo speakers shipped from Bangkok, authorities said on Friday. (telegraph.co.uk)
- In the Synthetic Drug Control Strategy released earlier this year, my Administration set goals of a 15 percent decrease in methamphetamine use and 25 percent reduction in domestic methamphetamine labs over the next 3 years. (archives.gov)
- The United Nations sounded the alarm over record seizures of methamphetamine across much of Asia as the illegal drug floods clubs and streets. (medindia.net)
- In its pill form, methamphetamine -- known in Thailand as "yaba", which means "crazy medicine" -- is used both as a party drug and pick-me-up for those working long hours. (medindia.net)
- Methamphetamine or ice users are more likelier to suffer psychotic symptoms while taking the drug, finds study. (medindia.net)
- Most often, teens become aware of methamphetamine in high school or college, when they take the drug to stay awake for hours on end to study. (soberrecovery.com)
- In United States, Methamphetamine has been approved by the Food and Drug Administration (FDA) in treating ADHD and exogenous obesity (obesity originating from factors outside of the patient's control) in both adults and children. (smore.com)
- Methamphetamine causes numerous neurotransmitters to be released in the brain, producing a sense of euphoria that may last as long as 12 hours, depending on how the drug was taken. (smore.com)
- MONTICELLO, Ill. (AP) - A dozen people are facing drug conspiracy charges following a five-month investigation into an alleged methamphetamine ring in the Cerro Gordo area. (washingtontimes.com)
- The newspaper reports that Belleville told investigators on Tuesday that he had not used methamphetamine in several months, but he later admitted to using the drug in January. (washingtontimes.com)
- Methamphetamine use in Spain is very low, but a concentration of users in Barcelona and recent busts have caused concern that the drug could spread to other communities in the country. (businessinsider.com)
- Spanish police broke up a drug ring smuggling methamphetamine using packages of chocolates, December 2014. (businessinsider.com)
- Rizwan Shah, medical director of the Drug Affected Babies Clinic at Blank Children's Hospital in Des Moines, is one of the few U.S. pediatricians to study children exposed to methamphetamine in the womb. (chicagotribune.com)
- The limited usefulness of methamphetamine should be weighed against possible risks inherent in use of the drug, such as those described below. (rxlist.com)
- The researchers found elevated Cho levels in the methamphetamine users who had not used the drug in one to six months, but normalized levels in the longer abstainers. (news-medical.net)
- Law enforcement used a confidential informant to purchase methamphetamine from Esparza, who has a history of drug dealing. (irs.gov)
- Monterey County Sheriff's deputies served a warrant Tuesday at the home of Sheriff Scott Miller's 25-year-old son, Jacob, for felony possession of a controlled substance for sale (methamphetamine), an infraction for marijuana possession, and a misdemeanor for possession of drug. (calcoastnews.com)
- That very day I thought that no one is spared from the perils and iron clutches of this drug world and I must write about methamphetamine effects and its cruelness to mankind. (hubpages.com)
- Methamphetamine is a highly addictive drug with becoming addict with just a single use. (hubpages.com)
- Investigators seized close to half a tonne of the drug methamphetamine just outside the city of Atlanta in one of the biggest such finds in US history, authorities have said. (bbc.com)
- Crystal methamphetamine and liquid methamphetamine oil were discovered in a large drug lab, the authorities said. (bbc.com)
- Of those visits, over 1.7 million were drug related and approximately 80,000 were for issues where methamphetamine was involved. (stopaddiction.com)
- The National Drug Intelligence Center reports that there are almost 5,000 Federal arrests each year for methamphetamine charges. (stopaddiction.com)
- Methamphetamine use also raises the risk of contracting infectious diseases like HIV and hepatitis B and C. These can be contracted both by sharing contaminated drug injection equipment and through unsafe sex. (streetdrugs.org)
- Studies indicate that HIV causes more injury to neurons and greater cognitive impairment in individuals who are HIV-positive and use methamphetamine than it does in HIV-positive people who do not use the drug. (streetdrugs.org)
- A new study at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory suggests that vigabatrin (a.k.a. gamma vinyl-GABA, or GVG) blocks drug-seeking behavior in animals previously trained to associate methamphetamine with a particular environment. (innovations-report.com)
Bags of methamphetamine1
- A policeman guards bags of methamphetamine pills at a ceremony to destroy narcotics in Ayutthaya province, nearly 50 miles north of Bangkok, June 24, 2005. (reuters.com)
Effect of methamphetamine1
- Their chemical structures are similar, although the effect of methamphetamine on the central nervous system is more pronounced. (drugpolicy.org)
Supply of methamphetamine2
- In mid-1995, a government effort to reduce the supply of methamphetamine precursors successfully disrupted the methamphetamine market and interrupted a trajectory of increasing usage. (marginalrevolution.com)
- Detective Senior Sergeant Brent Matuku says the arrests follow an investigation into the sale and supply of methamphetamine in the Taranaki area. (scoop.co.nz)
Seizures of methamphetamine1
- In 2007, the York Regional Police made 25 seizures of methamphetamine totalling 3445 g. (cmaj.ca)
- Although felony methamphetamine arrests fell 50 percent, there is no evidence of substantial reductions in property or violent crime. (marginalrevolution.com)
- Police have made three arrests, seized methamphetamine, cash and a luxury vehicle following an operation targeting organised crime in Taranaki. (scoop.co.nz)
- Police intercepted one package that had 200 grams of ice methamphetamine in it. (radioiowa.com)
- Following a five-day jury trial in August, Alejandro Ramirez-Suarez, 38 of San Jose, was convicted of conspiracy to possess with intent to distribute and to distribute 500 grams and more of methamphetamine. (mercurynews.com)
- Marcos Martinez-Corcuera, of the 600 block of Cleveland Street, was arrested Wednesday and charged with unlawful delivery of more than 400 grams of methamphetamine. (dailyherald.com)
- Getty's occasional girlfriend, Lanessa DeJonge, 32, told investigators that he consumed an "8 ball," or about 3.5 grams of methamphetamine, per day, according to the report. (chicagotribune.com)
- In one of the vehicles 11 grams of methamphetamine was found as well as an envelope containing a large quantity of cash. (scoop.co.nz)
- Withdrawal off of methamphetamine after heavy use may lead to a post-acute-withdrawal syndrome, which can persist for months beyond the typical withdrawal period. (wikipedia.org)
- The discontinued use of methamphetamine by heavy users will create withdrawal symptoms, including severe depression, lethargy, anxiety and fearfulness. (drugpolicy.org)
- Withdrawal symptoms in abstinent methamphetamine-dependent subjec. (ingentaconnect.com)
- Depressive and psychotic symptoms accompany acute withdrawal from methamphetamine but resolve within 1 week. (ingentaconnect.com)
- Methamphetamine neurotoxicity causes adverse changes in brain structure and function, such as reductions in grey matter volume in several brain regions, as well as adverse changes in markers of metabolic integrity. (wikipedia.org)
- The 2014 legislative cycle in a number of states will witness efforts to curtail the methamphetamine labs that cause so much death, destruction and environmental despoliation from West Virginia to Oklahoma. (washingtonmonthly.com)
- See the Methamphetamine Labs link). (streetdrugs.org)
- You can also get the Methamphetamine Labs Production Chart. (streetdrugs.org)
- This animal study suggests that vigabatrin could potentially prevent human methamphetamine addicts from relapsing. (innovations-report.com)
- Mexican and Asian criminal groups transport methamphetamine typically using couriers on commercial flights or via package delivery services. (justice.gov)
- At the end of 2014, Spanish police busted a smuggling ring mostly made up of Nigerians that was using human couriers to transport methamphetamine from Spain to Japan, usually hidden in chocolates. (businessinsider.com)
- Forty-two-year-old Roger Hettinger of Manchester pleaded guilty in May to importation of pseudoepherine, possession of illegal silencers and possession of pseudoepherine with the intent to manufacture methamphetamine. (radioiowa.com)
- Which cutaneous findings suggest methamphetamine toxicity? (medscape.com)
- Methamphetamine toxicity and messengers of death. (medscape.com)
- Kashani J, Ruha AM. Methamphetamine toxicity secondary to intravaginal body stuffing. (medscape.com)
- Most cases of methamphetamine toxicity can be managed supportively. (medscape.com)
- Toxicity from these chemicals can remain in the environment around a methamphetamine production lab long after the lab has been shut down, causing a wide range of health problems for people living in the area. (streetdrugs.org)