Arteries which arise from the abdominal aorta and distribute to most of the intestines.
A large vessel supplying the whole length of the small intestine except the superior part of the duodenum. It also supplies the cecum and the ascending part of the colon and about half the transverse part of the colon. It arises from the anterior surface of the aorta below the celiac artery at the level of the first lumbar vertebra.
The artery supplying nearly all the left half of the transverse colon, the whole of the descending colon, the sigmoid colon, and the greater part of the rectum. It is smaller than the superior mesenteric artery (MESENTERIC ARTERY, SUPERIOR) and arises from the aorta above its bifurcation into the common iliac arteries.
The vessels carrying blood away from the heart.
Obstruction of the flow in the SPLANCHNIC CIRCULATION by ATHEROSCLEROSIS; EMBOLISM; THROMBOSIS; STENOSIS; TRAUMA; and compression or intrinsic pressure from adjacent tumors. Rare causes are drugs, intestinal parasites, and vascular immunoinflammatory diseases such as PERIARTERITIS NODOSA and THROMBOANGIITIS OBLITERANS. (From Juergens et al., Peripheral Vascular Diseases, 5th ed, pp295-6)
DUODENAL OBSTRUCTION by the superior mesenteric artery (MESENTERIC ARTERY, SUPERIOR) which travels in the root of the MESENTERY and crosses over the DUODENUM. The syndrome is characterized by the dilated proximal duodenum and STOMACH, bloating, ABDOMINAL CRAMPS, and VOMITING. Often it is observed in patient with body casts after spinal surgery.
The arterial trunk that arises from the abdominal aorta and after a short course divides into the left gastric, common hepatic and splenic arteries.
The short wide vessel arising from the conus arteriosus of the right ventricle and conveying unaerated blood to the lungs.
A branch of the abdominal aorta which supplies the kidneys, adrenal glands and ureters.
The arterial blood vessels supplying the CEREBRUM.
The nonstriated involuntary muscle tissue of blood vessels.
The physiological widening of BLOOD VESSELS by relaxing the underlying VASCULAR SMOOTH MUSCLE.
Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.
The physiological narrowing of BLOOD VESSELS by contraction of the VASCULAR SMOOTH MUSCLE.
The main artery of the thigh, a continuation of the external iliac artery.
The circulation of blood through the BLOOD VESSELS supplying the abdominal VISCERA.
The artery formed by the union of the right and left vertebral arteries; it runs from the lower to the upper border of the pons, where it bifurcates into the two posterior cerebral arteries.
Endogenously-synthesized compounds that influence biological processes not otherwise classified under ENZYMES; HORMONES or HORMONE ANTAGONISTS.
Drugs used to cause constriction of the blood vessels.
Drugs used to cause dilation of the blood vessels.
Veins which return blood from the intestines; the inferior mesenteric vein empties into the splenic vein, the superior mesenteric vein joins the splenic vein to form the portal vein.
Either of two large arteries originating from the abdominal aorta; they supply blood to the pelvis, abdominal wall and legs.
The largest branch of the celiac trunk with distribution to the spleen, pancreas, stomach and greater omentum.
Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
The first branch of the SUBCLAVIAN ARTERY with distribution to muscles of the NECK; VERTEBRAE; SPINAL CORD; CEREBELLUM; and interior of the CEREBRUM.
Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.
A branch of the celiac artery that distributes to the stomach, pancreas, duodenum, liver, gallbladder, and greater omentum.
The recording of muscular movements. The apparatus is called a myograph, the record or tracing, a myogram. (From Stedman, 25th ed)
An alpha-1 adrenergic agonist used as a mydriatic, nasal decongestant, and cardiotonic agent.
The direct continuation of the brachial trunk, originating at the bifurcation of the brachial artery opposite the neck of the radius. Its branches may be divided into three groups corresponding to the three regions in which the vessel is situated, the forearm, wrist, and hand.
Arteries originating from the subclavian or axillary arteries and distributing to the anterior thoracic wall, mediastinal structures, diaphragm, pectoral muscles and mammary gland.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
Branch of the common carotid artery which supplies the anterior part of the brain, the eye and its appendages, the forehead and nose.
Artery arising from the brachiocephalic trunk on the right side and from the arch of the aorta on the left side. It distributes to the neck, thoracic wall, spinal cord, brain, meninges, and upper limb.
Surgical formation of an opening into the DUODENUM.
A strain of Rattus norvegicus used as a normotensive control for the spontaneous hypertensive rats (SHR).
That phase of a muscle twitch during which a muscle returns to a resting position.
Pathological conditions involving the CAROTID ARTERIES, including the common, internal, and external carotid arteries. ATHEROSCLEROSIS and TRAUMA are relatively frequent causes of carotid artery pathology.
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
The veins and arteries of the HEART.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Radiography of blood vessels after injection of a contrast medium.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
The continuation of the axillary artery; it branches into the radial and ulnar arteries.
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
The relationship between the dose of an administered drug and the response of the organism to the drug.
Paracrine substances produced by the VASCULAR ENDOTHELIUM with VASCULAR SMOOTH MUSCLE relaxation (VASODILATION) activities. Several factors have been identified, including NITRIC OXIDE and PROSTACYCLIN.
The two principal arteries supplying the structures of the head and neck. They ascend in the neck, one on each side, and at the level of the upper border of the thyroid cartilage, each divides into two branches, the external (CAROTID ARTERY, EXTERNAL) and internal (CAROTID ARTERY, INTERNAL) carotid arteries.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
A strain of Rattus norvegicus with elevated blood pressure used as a model for studying hypertension and stroke.
Pathological outpouching or sac-like dilatation in the wall of any blood vessel (ARTERIES or VEINS) or the heart (HEART ANEURYSM). It indicates a thin and weakened area in the wall which may later rupture. Aneurysms are classified by location, etiology, or other characteristics.
Narrowing or occlusion of the RENAL ARTERY or arteries. It is due usually to ATHEROSCLEROSIS; FIBROMUSCULAR DYSPLASIA; THROMBOSIS; EMBOLISM, or external pressure. The reduced renal perfusion can lead to renovascular hypertension (HYPERTENSION, RENOVASCULAR).
Artery originating from the internal carotid artery and distributing to the eye, orbit and adjacent facial structures.
A stable prostaglandin endoperoxide analog which serves as a thromboxane mimetic. Its actions include mimicking the hydro-osmotic effect of VASOPRESSIN and activation of TYPE C PHOSPHOLIPASES. (From J Pharmacol Exp Ther 1983;224(1): 108-117; Biochem J 1984;222(1):103-110)
A 37-amino acid residue peptide isolated from the scorpion Leiurus quinquestriatus hebraeus. It is a neurotoxin that inhibits calcium activated potassium channels.
A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.
A non-selective inhibitor of nitric oxide synthase. It has been used experimentally to induce hypertension.
The flow of BLOOD through or around an organ or region of the body.
Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.
Specialized arterial vessels in the umbilical cord. They carry waste and deoxygenated blood from the FETUS to the mother via the PLACENTA. In humans, there are usually two umbilical arteries but sometimes one.
The largest of the cerebral arteries. It trifurcates into temporal, frontal, and parietal branches supplying blood to most of the parenchyma of these lobes in the CEREBRAL CORTEX. These are the areas involved in motor, sensory, and speech activities.
Arteries originating from the subclavian or axillary arteries and distributing to the anterior thoracic wall, mediastinal structures, diaphragm, pectoral muscles, mammary gland and the axillary aspect of the chest wall.
Elements of limited time intervals, contributing to particular results or situations.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.
The condition of an anatomical structure's being constricted beyond normal dimensions.
Arteries arising from the external carotid or the maxillary artery and distributing to the temporal region.
Left bronchial arteries arise from the thoracic aorta, the right from the first aortic intercostal or the upper left bronchial artery; they supply the bronchi and the lower trachea.
A non-steroidal anti-inflammatory agent (NSAID) that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids. It also inhibits the motility of polymorphonuclear leukocytes.
Ultrasonography applying the Doppler effect, with frequency-shifted ultrasound reflections produced by moving targets (usually red blood cells) in the bloodstream along the ultrasound axis in direct proportion to the velocity of movement of the targets, to determine both direction and velocity of blood flow. (Stedman, 25th ed)
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
A powerful vasodilator used in emergencies to lower blood pressure or to improve cardiac function. It is also an indicator for free sulfhydryl groups in proteins.
The continuation of the femoral artery coursing through the popliteal fossa; it divides into the anterior and posterior tibial arteries.
The main trunk of the systemic arteries.
The larger of the two terminal branches of the brachial artery, beginning about one centimeter distal to the bend of the elbow. Like the RADIAL ARTERY, its branches may be divided into three groups corresponding to their locations in the forearm, wrist, and hand.
An NADPH-dependent enzyme that catalyzes the conversion of L-ARGININE and OXYGEN to produce CITRULLINE and NITRIC OXIDE.
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
The portion of the descending aorta proceeding from the arch of the aorta and extending to the DIAPHRAGM, eventually connecting to the ABDOMINAL AORTA.
The neural systems which act on VASCULAR SMOOTH MUSCLE to control blood vessel diameter. The major neural control is through the sympathetic nervous system.
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
A highly neurotoxic polypeptide from the venom of the honey bee (Apis mellifera). It consists of 18 amino acids with two disulfide bridges and causes hyperexcitability resulting in convulsions and respiratory paralysis.
A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
A branch arising from the internal iliac artery in females, that supplies blood to the uterus.
An inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity. Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced alterations in brain energy and ammonia metabolites. (Neurochem Res 1995:200(4):451-6)
The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.
A steroid metabolite that is the 11-deoxy derivative of CORTICOSTERONE and the 21-hydroxy derivative of PROGESTERONE.
The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Radiography of the vascular system of the heart muscle after injection of a contrast medium.
The aorta from the DIAPHRAGM to the bifurcation into the right and left common iliac arteries.
A CALCIUM-dependent, constitutively-expressed form of nitric oxide synthase found primarily in ENDOTHELIAL CELLS.
The state of activity or tension of a muscle beyond that related to its physical properties, that is, its active resistance to stretch. In skeletal muscle, tonus is dependent upon efferent innervation. (Stedman, 25th ed)
Branch of the common carotid artery which supplies the exterior of the head, the face, and the greater part of the neck.
Surgical insertion of BLOOD VESSEL PROSTHESES to repair injured or diseased blood vessels.
A class of drugs that act by inhibition of potassium efflux through cell membranes. Blockade of potassium channels prolongs the duration of ACTION POTENTIALS. They are used as ANTI-ARRHYTHMIA AGENTS and VASODILATOR AGENTS.
A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
Damages to the CAROTID ARTERIES caused either by blunt force or penetrating trauma, such as CRANIOCEREBRAL TRAUMA; THORACIC INJURIES; and NECK INJURIES. Damaged carotid arteries can lead to CAROTID ARTERY THROMBOSIS; CAROTID-CAVERNOUS SINUS FISTULA; pseudoaneurysm formation; and INTERNAL CAROTID ARTERY DISSECTION. (From Am J Forensic Med Pathol 1997, 18:251; J Trauma 1994, 37:473)
Adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to the tissue (REPERFUSION), including swelling; HEMORRHAGE; NECROSIS; and damage from FREE RADICALS. The most common instance is MYOCARDIAL REPERFUSION INJURY.
An unstable intermediate between the prostaglandin endoperoxides and thromboxane B2. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of platelet aggregation and causes vasoconstriction. It is the principal component of rabbit aorta contracting substance (RCS).
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)
Operative procedures for the treatment of vascular disorders.
Use of electric potential or currents to elicit biological responses.
A potassium-channel opening vasodilator that has been investigated in the management of hypertension. It has also been tried in patients with asthma. (Martindale, The Extra Pharmacopoeia, 30th ed, p352)
A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage.
Application of a ligature to tie a vessel or strangulate a part.
The degree to which BLOOD VESSELS are not blocked or obstructed.
Muscular contractions characterized by increase in tension without change in length.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.
Not an aneurysm but a well-defined collection of blood and CONNECTIVE TISSUE outside the wall of a blood vessel or the heart. It is the containment of a ruptured blood vessel or heart, such as sealing a rupture of the left ventricle. False aneurysm is formed by organized THROMBUS and HEMATOMA in surrounding tissue.
Calcitonin gene-related peptide. A 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in neural tissue of the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator.
Use of a balloon catheter for dilation of an occluded artery. It is used in treatment of arterial occlusive diseases, including renal artery stenosis and arterial occlusions in the leg. For the specific technique of BALLOON DILATION in coronary arteries, ANGIOPLASTY, BALLOON, CORONARY is available.
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
An alpha-1 adrenergic agonist that causes prolonged peripheral VASOCONSTRICTION.
Any of the large interior organs in any one of the three great cavities of the body, especially in the abdomen.
An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
Non-striated, elongated, spindle-shaped cells found lining the digestive tract, uterus, and blood vessels. They are derived from specialized myoblasts (MYOBLASTS, SMOOTH MUSCLE).
Aneurysm caused by a tear in the TUNICA INTIMA of a blood vessel leading to interstitial HEMORRHAGE, and splitting (dissecting) of the vessel wall, often involving the AORTA. Dissection between the intima and media causes luminal occlusion. Dissection at the media, or between the media and the outer adventitia causes aneurismal dilation.
Drugs that selectively bind to and activate alpha adrenergic receptors.
A subclass of alpha-adrenergic receptors that mediate contraction of SMOOTH MUSCLE in a variety of tissues such as ARTERIOLES; VEINS; and the UTERUS. They are usually found on postsynaptic membranes and signal through GQ-G11 G-PROTEINS.
A short thick vein formed by union of the superior mesenteric vein and the splenic vein.
Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.
NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
The continuation of the subclavian artery; it distributes over the upper limb, axilla, chest and shoulder.
A layer of the peritoneum which attaches the abdominal viscera to the ABDOMINAL WALL and conveys their blood vessels and nerves.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Pentacyclic triterpene saponins, biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of AESCULUS. It inhibits edema formation and decreases vascular fragility.
Sudden ISCHEMIA in the RETINA due to blocked blood flow through the CENTRAL RETINAL ARTERY or its branches leading to sudden complete or partial loss of vision, respectively, in the eye.
Short thick veins which return blood from the kidneys to the vena cava.
The tearing or bursting of the weakened wall of the aneurysmal sac, usually heralded by sudden worsening pain. The great danger of a ruptured aneurysm is the large amount of blood spilling into the surrounding tissues and cavities, causing HEMORRHAGIC SHOCK.
Hindrance of the passage of luminal contents in the DUODENUM. Duodenal obstruction can be partial or complete, and caused by intrinsic or extrinsic factors. Simple obstruction is associated with diminished or stopped flow of luminal contents. Strangulating obstruction is associated with impaired blood flow to the duodenum in addition to obstructed flow of luminal contents.
Potassium channels whose activation is dependent on intracellular calcium concentrations.
Blood clot formation in any part of the CAROTID ARTERIES. This may produce CAROTID STENOSIS or occlusion of the vessel, leading to TRANSIENT ISCHEMIC ATTACK; CEREBRAL INFARCTION; or AMAUROSIS FUGAX.
A class of drugs that act by selective inhibition of calcium influx through cellular membranes.
Compounds that bind to and activate ADRENERGIC ALPHA-1 RECEPTORS.
An abnormal balloon- or sac-like dilatation in the wall of the ABDOMINAL AORTA which gives rise to the visceral, the parietal, and the terminal (iliac) branches below the aortic hiatus at the diaphragm.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Arteries which supply the dura mater.
The section of the alimentary canal from the STOMACH to the ANAL CANAL. It includes the LARGE INTESTINE and SMALL INTESTINE.
Cell membrane glycoproteins that are selectively permeable to potassium ions. At least eight major groups of K channels exist and they are made up of dozens of different subunits.
Ultrasonography applying the Doppler effect combined with real-time imaging. The real-time image is created by rapid movement of the ultrasound beam. A powerful advantage of this technique is the ability to estimate the velocity of flow from the Doppler shift frequency.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
An antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.
Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.
Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.
A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
Radiographic visualization of the aorta and its branches by injection of contrast media, using percutaneous puncture or catheterization procedures.
Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)
21-Amino-acid peptides produced by vascular endothelial cells and functioning as potent vasoconstrictors. The endothelin family consists of three members, ENDOTHELIN-1; ENDOTHELIN-2; and ENDOTHELIN-3. All three peptides contain 21 amino acids, but vary in amino acid composition. The three peptides produce vasoconstrictor and pressor responses in various parts of the body. However, the quantitative profiles of the pharmacological activities are considerably different among the three isopeptides.
Compounds with a core of fused benzo-pyran rings.
A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
A compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue color. Methylene blue is used as a bacteriologic stain and as an indicator. It inhibits GUANYLATE CYCLASE, and has been used to treat cyanide poisoning and to lower levels of METHEMOGLOBIN.
The synapse between a neuron (presynaptic) and an effector cell other than another neuron (postsynaptic). Neuroeffector junctions include synapses onto muscles and onto secretory cells.
A derivative of the NIACINAMIDE that is structurally combined with an organic nitrate. It is a potassium-channel opener that causes vasodilatation of arterioles and large coronary arteries. Its nitrate-like properties produce venous vasodilation through stimulation of guanylate cyclase.
A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
Minimally invasive procedures, diagnostic or therapeutic, performed within the BLOOD VESSELS. They may be perfomed via ANGIOSCOPY; INTERVENTIONAL MAGNETIC RESONANCE IMAGING; INTERVENTIONAL RADIOGRAPHY; or INTERVENTIONAL ULTRASONOGRAPHY.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
An essential amino acid that is physiologically active in the L-form.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels.
A method of delineating blood vessels by subtracting a tissue background image from an image of tissue plus intravascular contrast material that attenuates the X-ray photons. The background image is determined from a digitized image taken a few moments before injection of the contrast material. The resulting angiogram is a high-contrast image of the vessel. This subtraction technique allows extraction of a high-intensity signal from the superimposed background information. The image is thus the result of the differential absorption of X-rays by different tissues.
Reconstruction or repair of a blood vessel, which includes the widening of a pathological narrowing of an artery or vein by the removal of atheromatous plaque material and/or the endothelial lining as well, or by dilatation (BALLOON ANGIOPLASTY) to compress an ATHEROMA. Except for ENDARTERECTOMY, usually these procedures are performed via catheterization as minimally invasive ENDOVASCULAR PROCEDURES.
A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.
Radiography of the vascular system of the brain after injection of a contrast medium.
A diverse group of agents, with unique chemical structures and biochemical requirements, which generate NITRIC OXIDE. These compounds have been used in the treatment of cardiovascular diseases and the management of acute myocardial infarction, acute and chronic congestive heart failure, and surgical control of blood pressure. (Adv Pharmacol 1995;34:361-81)
A competitive inhibitor of nitric oxide synthetase.
Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.
A major class of calcium-activated potassium channels that were originally discovered in ERYTHROCYTES. They are found primarily in non-excitable CELLS and set up electrical gradients for PASSIVE ION TRANSPORT.
Drugs that bind to and block the activation of ADRENERGIC ALPHA-1 RECEPTORS.
Rhythmic, intermittent propagation of a fluid through a BLOOD VESSEL or piping system, in contrast to constant, smooth propagation, which produces laminar flow.
A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
Surgical formation of an opening through the ABDOMINAL WALL into the JEJUNUM, usually for enteral hyperalimentation.
Any of the tubular vessels conveying the blood (arteries, arterioles, capillaries, venules, and veins).
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Cell surface proteins that bind ENDOTHELINS with high affinity and trigger intracellular changes which influence the behavior of cells.
Delivery of drugs into an artery.
A branch of the external carotid artery which distributes to the deep structures of the face (internal maxillary) and to the side of the face and nose (external maxillary).
The portion of the GASTROINTESTINAL TRACT between the PYLORUS of the STOMACH and the ILEOCECAL VALVE of the LARGE INTESTINE. It is divisible into three portions: the DUODENUM, the JEJUNUM, and the ILEUM.
Cell surface proteins that bind PURINES with high affinity and trigger intracellular changes which influence the behavior of cells. The best characterized classes of purinergic receptors in mammals are the P1 receptors, which prefer ADENOSINE, and the P2 receptors, which prefer ATP or ADP.
Benzopyrroles with the nitrogen at the number one carbon adjacent to the benzyl portion, in contrast to ISOINDOLES which have the nitrogen away from the six-membered ring.
Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)
The act of constricting.
The circulation of blood through the CORONARY VESSELS of the HEART.
The splitting of the vessel wall in one or both (left and right) internal carotid arteries (CAROTID ARTERY, INTERNAL). Interstitial hemorrhage into the media of the vessel wall can lead to occlusion of the internal carotid artery and aneurysm formation.
A group of compounds derived from unsaturated 20-carbon fatty acids, primarily arachidonic acid, via the cyclooxygenase pathway. They are extremely potent mediators of a diverse group of physiological processes.
Ultrasonography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image. This type of ultrasonography is well-suited to identifying the location of high-velocity flow (such as in a stenosis) or of mapping the extent of flow in a certain region.
Cell surface proteins that bind THROMBOXANES with high affinity and trigger intracellular changes influencing the behavior of cells. Some thromboxane receptors act via the inositol phosphate and diacylglycerol second messenger systems.
Blocking of a blood vessel by an embolus which can be a blood clot or other undissolved material in the blood stream.
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
Coronary artery bypass surgery on a beating HEART without a CARDIOPULMONARY BYPASS (diverting the flow of blood from the heart and lungs through an oxygenator).
A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.
Direct myocardial revascularization in which the internal mammary artery is anastomosed to the right coronary artery, circumflex artery, or anterior descending coronary artery. The internal mammary artery is the most frequent choice, especially for a single graft, for coronary artery bypass surgery.

Observations on some additional abnormalities in situs inversus viscerum. (1/2143)

The abnormal findings in a case of Situs inversus totalis are described. The duodenum was placed abnormally and retained its primitive mesentery. The proximal 22 in of jejunum were retroperitoneal. The attachment of the root of the mesentery to the posterior abdominal wall had a 7-shaped appearance, and there was a partial failure of the primitive mesocolon to adhere to the posterior abdominal wall. The common hepatic artery arose from the superior meseneric artery, which also provided a branch to the proximal jejunal loop. The right vagus nerve was found anterior to the oesophagus at the oesophageal hiatus in the diaphragm, and the left vagus was posterior. A double ureter was present on the right side. The findings are discussed in relation to mid-gut development.  (+info)

Acetylcholine-induced relaxation in blood vessels from endothelial nitric oxide synthase knockout mice. (2/2143)

1. Isometric tension was recorded in isolated rings of aorta, carotid, coronary and mesenteric arteries taken from endothelial nitric oxide synthase knockout mice (eNOS(-/-) mice) and the corresponding wild-type strain (eNOS(+/+) mice). The membrane potential of smooth muscle cells was measured in coronary arteries with intracellular microelectrodes. 2. In the isolated aorta, carotid and coronary arteries from the eNOS(+/+) mice, acetylcholine induced an endothelium-dependent relaxation which was inhibited by N(omega)-L-nitro-arginine. In contrast, in the mesenteric arteries, the inhibition of the cholinergic relaxation required the combination of N(omega)-L-nitro-arginine and indomethacin. 3. The isolated aorta, carotid and coronary arteries from the eNOS(-/-) mice did not relax in response to acetylcholine. However, acetylcholine produced an indomethacin-sensitive relaxation in the mesenteric artery from eNOS(-/-) mice. 4. The resting membrane potential of smooth muscle cells from isolated coronary arteries was significantly less negative in the eNOS(-/-) mice (-64.8 +/- 1.8 mV, n = 20 and -58.4 +/- 1.9 mV, n = 17, for eNOS(+/+) and eNOS(-/-) mice, respectively). In both strains, acetylcholine, bradykinin and substance P did not induce endothelium-dependent hyperpolarizations whereas cromakalim consistently produced hyperpolarizations (- 7.9 +/- 1.1 mV, n = 8 and -13.8 +/- 2.6 mV, n = 4, for eNOS(+/+) and eNOS(-/-) mice, respectively). 5. These findings demonstrate that in the blood vessels studied: (1) in the eNOS(+/+) mice, the endothelium-dependent relaxations to acetylcholine involve either NO or the combination of NO plus a product of cyclo-oxygenase but not EDHF; (2) in the eNOS(-/-) mice, NO-dependent responses and EDHF-like responses were not observed. In the mesenteric arteries acetylcholine releases a cyclo-oxygenase derivative.  (+info)

Studies of the role of endothelium-dependent nitric oxide release in the sustained vasodilator effects of corticotrophin releasing factor and sauvagine. (3/2143)

1. The mechanisms of the sustained vasodilator actions of corticotrophin-releasing factor (CRF) and sauvagine (SVG) were studied using rings of endothelium de-nuded rat thoracic aorta (RTA) and the isolated perfused rat superior mesenteric arterial vasculature (SMA). 2. SVG was approximately 50 fold more potent than CRF on RTA (EC40: 0.9 +/- 0.2 and 44 +/- 9 nM respectively, P < 0.05), and approximately 10 fold more active in the perfused SMA (ED40: 0.05 +/- 0.02 and 0.6 +/- 0.1 nmol respectively, P < 0.05). Single bolus injections of CRF (100 pmol) or SVG (15 pmol) in the perfused SMA caused reductions in perfusion pressure of 23 +/- 1 and 24 +/- 2% that lasted more than 20 min. 3. Removal of the endothelium in the perfused SMA with deoxycholic acid attenuated the vasodilatation and revealed two phases to the response; a short lasting direct action, and a sustained phase which was fully inhibited. 4. Inhibition of nitric oxide synthase with L-NAME (100 microM) L-NMMA (100 microM) or 2-ethyl-2-thiopseudourea (ETPU, 100 microM) had similar effects on the vasodilator responses to CRF as removal of the endothelium, suggesting a pivotal role for nitric oxide. However the selective guanylate cyclase inhibitor 1H-[l,2,4]oxadiazolo[4,3-alpha]quinoxalin-1-one (ODQ, 10 microM) did not affect the response to CRF. 5. High potassium (60 mM) completely inhibited the vasodilator response to CRF in the perfused SMA, indicating a role for K channels in this response. 6. Compared to other vasodilator agents acting via the release of NO, the actions of CRF and SVG are strikingly long-lasting, suggesting a novel mechanism of prolonged activation of nitric oxide synthase.  (+info)

Altered vascular reactivity following partial nephrectomy in the rat: a possible mechanism of the blood-pressure-lowering effect of heparin. (4/2143)

BACKGROUND: This study was designed to assess whether the antihypertensive effect of heparin in rats after renal mass reduction (RMR) is related to changes in nitric oxide activity, and to study in vitro the altered behaviour of resistance-sized arteries induced by chronic administration of heparin. METHODS: Male Wistar rats were assigned to one of two experimental protocols. In the first protocol, RMR rats received heparin (250 units/day s.c.) and tail systolic blood pressure (SBP) was measured weekly for 4 weeks. In a subgroup, urinary nitrate excretion (UNO3) and in vitro vascular reactivity of isolated perfused mesenteric arterial beds were measured 2 weeks after RMR. The second protocol assessed whether inhibition of NO synthesis with L-NAME (70 mg/l added to the drinking water) prevents the blood-pressure-lowering effect of heparin. RESULTS: In untreated RMR rats SBP increased from 111+/-3 mmHg to 127+/-5 mmHg at 2 weeks and 139+/-5 mmHg at 4 weeks. In contrast, in RMR rats treated with heparin, SBP was 114 +/-3 mmHg at 2 weeks and 115+/-4 mmHg at 4 weeks (P<0.05 for both). Treatment with L-NAME increased SBP both in untreated and heparin-treated RMR groups. Two weeks after nephrectomy daily urinary nitrate increased significantly more in RMR rats treated with heparin than in untreated RMR rats (22+/-2 vs 14.2+/-2.3 micromol/day, P<0.05). In vitro studies performed at 2 weeks showed that vessels of untreated RMR rats had a blunted vasodilator response to acetylcholine that was restored to levels similar to that of controls in the heparin-treated group. CONCLUSIONS: These results suggest that, in rats after renal ablation, heparin may exert its antihypertensive effect, at least in part, by affecting the altered behaviour of resistance vessels during the development phase of hypertension. Increased NO production may contribute to this effect.  (+info)

Maintenance of normal agonist-induced endothelium-dependent relaxation in uraemic and hypertensive resistance vessels. (5/2143)

BACKGROUND: The nitric oxide system has been implicated in several diseases with vascular complications including diabetes mellitus and hypertension. Despite the high prevalence of hypertension and cardiovascular complications in renal failure few studies have examined vascular and endothelial function in uraemia. We therefore chose to study possible abnormalities of the nitric oxide vasodilator system in an animal model of chronic renal failure. METHODS: Adult spontaneous hypertensive rats and Wistar Kyoto rats were subjected to a 5/6 nephrectomy with control animals having sham operations. After 4 weeks blood pressure was recorded and the animals were sacrificed. Branches of the mesenteric arteries were isolated and mounted on a Mulvany myograph. All experiments were performed in the presence of indomethacin (10(-5) M). The vessels were first preconstricted with noradrenaline, exposed to increasing concentrations of acetylcholine (10(-8) to 10(-4) M) and subsequently to sodium nitroprusside (10(-5) M). RESULTS: There was no difference in the relaxation of the four groups of vessels to any of the concentrations of acetylcholine used nor was there any significant difference in the EC50s (control Wistar Kyoto 6.1+/-1.4 x 10(-8) M; uraemic Wistar Kyoto 5.4+/-0.8 x 10(-8) M; control spontaneous hypertensive rats 4.5+/-0.6 x 10(-8) M; uraemic spontaneous hypertensive rats 6+/-0.7 x 10(-8) M). Vasodilatation in response to sodium nitroprusside was unchanged in uraemic vessels. In addition the vascular responses to both acetylcholine and sodium nitroprusside were unaltered in spontaneous hypertensive rats. CONCLUSIONS: We conclude that normal agonist-induced endothelium-dependent relaxation is maintained in experimental uraemia and hypertension.  (+info)

Modulation of temperature-induced tone by vasoconstrictor agents. (6/2143)

One of the primary cardiovascular adjustments to hyperthermia is a sympathetically mediated increase in vascular resistance in the viscera. Nonneural factors such as a change in vascular tone or reactivity may also contribute to this response. Therefore, the aim of this study was to determine whether vascular smooth muscle tone is altered during heating to physiologically relevant temperatures >37 degrees C. Gradually increasing bath temperature from 37 degrees C (normothermia) to 43 degrees C (severe hyperthermia) produced graded contractions in vascular ring segments from rat mesenteric arteries and thoracic aortae. In untreated rings these contractions were relatively small, whereas hyperthermia elicited near-maximal increases in tension when rings were constricted with phenylephrine or KCl before heating. In phenylephrine-treated mesenteric arterial rings, the contractile responses to heating were markedly attenuated by the Ca2+ channel antagonists nifedipine and diltiazem. Diltiazem also blocked the contractile responses to heating in thoracic aortic rings. These results demonstrate that hyperthermia has a limited effect on tension generation in rat vascular smooth muscle in the absence of vascular tone. However, in the presence of agonist-induced tone, tension generation during heating is markedly enhanced and dependent on extracellular Ca2+. In conclusion, these data suggest that local regulation of vascular tone can contribute to the hemodynamic adjustments to hyperthermia.  (+info)

Kir2.1 encodes the inward rectifier potassium channel in rat arterial smooth muscle cells. (7/2143)

1. The molecular nature of the strong inward rectifier K+ channel in vascular smooth muscle was explored by using isolated cell RT-PCR, cDNA cloning and expression techniques. 2. RT-PCR of RNA from single smooth muscle cells of rat cerebral (basilar), coronary and mesenteric arteries revealed transcripts for Kir2.1. Transcripts for Kir2.2 and Kir2.3 were not found. 3. Quantitative PCR analysis revealed significant differences in transcript levels of Kir2.1 between the different vascular preparations (n = 3; P < 0.05). A two-fold difference was detected between Kir2.1 mRNA and beta-actin mRNA in coronary arteries when compared with relative levels measured in mesenteric and basilar preparations. 4. Kir2.1 was cloned from rat mesenteric vascular smooth muscle cells and expressed in Xenopus oocytes. Currents were strongly inwardly rectifying and selective for K+. 5. The effect of extracellular Ba2+, Ca2+, Mg2+ and Cs2+ ions on cloned Kir2.1 channels expressed in Xenopus oocytes was examined. Ba2+ and Cs+ block were steeply voltage dependent, whereas block by external Ca2+ and Mg2+ exhibited little voltage dependence. The apparent half-block constants and voltage dependences for Ba2+, Cs+, Ca2+ and Mg2+ were very similar for inward rectifier K+ currents from native cells and cloned Kir2.1 channels expressed in oocytes. 6. Molecular studies demonstrate that Kir2.1 is the only member of the Kir2 channel subfamily present in vascular arterial smooth muscle cells. Expression of cloned Kir2.1 in Xenopus oocytes resulted in inward rectifier K+ currents that strongly resemble those that are observed in native vascular arterial smooth muscle cells. We conclude that Kir2.1 encodes for inward rectifier K+ channels in arterial smooth muscle.  (+info)

Mechanisms of hypoxic vasodilatation of isolated rat mesenteric arteries: a comparison with metabolic inhibition. (8/2143)

1. Hypoxia (PO2 < 5 mmHg) decreased vessel tone in isolated rat mesenteric arteries precontracted with either high [K+] or the thromboxane analogue U46619. This response was not altered by N-nitro-L-arginine (L-NA) and indomethacin. 2. Simultaneous measurement of pHi and tension showed that the decrease in vessel tone was accompanied by an intracellular acidification. Similar reductions in tone and pHi were observed with the metabolic inhibitors 2,4-dinitrophenol (DNP) and sodium azide. 3. The presence of the lactate transport inhibitor alpha-cyano-4-hydroxy-cinnamic acid (CHC) increased the magnitude of the acidification and resulted in a significantly faster reduction in tone in response to hypoxia. Addition of CHC to normoxic tissues caused both a vasodilatation and a reduction of pHi. 4. A decrease in pHi induced on washout of ammonium chloride (NH4Cl) resulted in an increase in tone. 5. Relaxation to hypoxia or metabolic inhibition was unaffected when the change in pHi was neutralized by addition of the weak base trimethylamine (TMA). 6. It is concluded that severe hypoxia decreases tone in isolated rat mesenteric arteries by a mechanism which is independent of nitric oxide and prostaglandins. Both severe hypoxia and metabolic inhibition reduced pHi, although this does not appear to be contributing to the changes in tone observed.  (+info)

TY - JOUR. T1 - The GPR55 agonist lysophosphatidylinositol relaxes rat mesenteric resistance artery and induces Ca2+ release in rat mesenteric artery endothelial cells. AU - Alsuleimani, Y. M.. AU - Hiley, C. R.. PY - 2015/6/1. Y1 - 2015/6/1. N2 - Background and Purpose Lysophosphatidylinositol (LPI), a lipid signalling molecule, activates GPR55 and elevates intracellular Ca2+. Here, we examine the actions of LPI in the rat resistance mesenteric artery and Ca2+ responses in endothelial cells isolated from the artery. Experimental Approach Vascular responses were studied using wire myographs. Single-cell fluorescence imaging was performed using a MetaFluor system. Hypotensive effects of LPI were assessed using a Biopac system. Key Results In isolated arteries, LPI-induced vasorelaxation was concentration- and endothelium-dependent and inhibited by CID 16020046, a GPR55 antagonist. The CB1 receptor antagonist AM 251 had no effect, whereas rimonabant and O-1918 significantly potentiated LPI ...
TY - JOUR. T1 - Assessing myogenic response and vasoactivity in resistance mesenteric arteries using pressure myography. AU - Jadeja, Ravirajsinh N.. AU - Rachakonda, Vikrant. AU - Bagi, Zsolt. AU - Khurana, Sandeep. PY - 2015/7/6. Y1 - 2015/7/6. N2 - Small resistance arteries constrict and dilate respectively in response to increased or decreased intraluminal pressure; this phenomenon known as myogenic response is a key regulator of local blood flow. In isobaric conditions small resistance arteries develop sustained constriction known as myogenic tone (MT), which is a major determinant of systemic vascular resistance (SVR). Hence, ex vivo pressurized preparations of small resistance arteries are major tools to study microvascular function in near-physiological states. To achieve this, a freshly isolated intact segment of a small resistance artery (diameter ~260 μm) is mounted onto two small glass cannulas and pressurized. These arterial preparations retain most in vivo characteristics and ...
We have investigated effects of altered extracellular sodium, intracellular sodium concentration, and membrane potential on the contractile responses of rat isolated mesenteric small arteries (internal diameter ca. 200 microns), when mounted as ring preparations on an isometric myograph. To avoid possible neural effects, all vessels were denervated in vitro using 6-hydroxydopamine. In unstimulated vessels, exposure to low-Na+ solutions (25 mM sodium, sucrose, or choline-substituted) did not cause any response nor did exposure to ouabain (1 mM) for 1 hour [when intracellular sodium concentration increased to 64 mmol/(liter-cell)]. However, a response was obtained if ouabain-exposed vessels were subjected to low-sodium solutions (ca. 15% of maximal response). The magnitude of the response was dependent on the ratio of intracellular to extracellular sodium and was not inhibitable by the calcium blockers, felodipine (1 nM) or D600 (10 microM). This response could therefore be explained in terms of ...
TY - JOUR. T1 - Mechanisms of vasorelaxation induced by oleoylethanolamide in the rat small mesenteric artery. AU - Alsuleimani, Yousuf M.. AU - Hiley, C. Robin. PY - 2013/2/28. Y1 - 2013/2/28. N2 - The actions of the anandamide-like mono-unsaturated fatty acid oleoylethanolamide (OEA) were first linked to satiety and control of food intake and recently reported to relax resistance vessels. This study characterizes its vasorelaxant mechanisms. Vasorelaxation to OEA were assessed in third order branches of rat superior mesenteric artery using a wire myograph. The roles of the endothelium, KCa channels, perivascular sensory nerves, NO, cannabinoid receptors, and the phospholipase C (PLC)/inositol trisphosphate (InsP3) and RhoA/ROCK signalling pathways, were assessed. OEA caused concentration- and endothelium-dependent vasorelaxation (pEC50=6.7±0.1, Rmax=93.1±2. 5%). L-NAME greatly reduced the response (residual relaxation of only 24.6±12.8%). Capsaicin and pertussis toxin significantly reduced ...
In WT mice, endothelium-dependent relaxations of small mesenteric arteries were mainly mediated by EDHF, whereas those of the aorta were mediated by NO, a finding that is consistent with our previous studies (2, 4, 14). Interestingly, EDHF-mediated relaxations were progressively reduced in accordance with the number of disrupted NOS genes in mesenteric arteries and were absent in n/i/eNOS−/− mice, indicating that EDHF-mediated relaxations are totally mediated by the endothelial NOSs system in mouse mesenteric arteries.. In this study, after the classical definition of EDHF (1-3), we evaluated EDHF-mediated responses in mouse mesenteric arteries in the presence of indomethacin and l-NNA. It is known that eNOS generates superoxide anions under normal conditions from reductase domain and only when uncoupled (e.g., BH4 and/or l-arginine depletion) from the oxidase domain, and that l-arginine analogues only inhibit the latter process (40). Indeed, we were able to demonstrate that endothelial ...
In the isolated canine mesenteric artery relaxation caused by nicorandil [N-(2-hydroxyethyl)nicotinamide nitrate ester; SG-75] in the presence of noradrenaline was accompanied by a concomitant...
1. In order to examine the effects of experimental hypertension on intracellular pH in mesenteric resistance arteries, intracellular pH was measured in mesenteric resistance arteries from rats with coarctation 72 h, 9 days and 28 days after the aorta was partially constricted between the origins of the renal arteries. Carotid arterial pressure was significantly raised at all time points.. 2. Second-order mesenteric resistance arteries were mounted in a myograph and were loaded with the acetoxymethyl ester of the pH-sensitive dye 2′,7′-bis(carboxyethyl)-5,6-carboxyfluorescein. Morphological measurements demonstrated that arteries from rats with coarctation had an increased media volume at 9 days and at 28 days compared with vessels from sham-operated control animals, but this was only statistically significant at 28 days.. 3. Resting intracellular pH was not significantly different at any time point in arteries from rats with coarctation compared with control animals, although there was a ...
1 the alpha(2)-adrenoceptor function in mesenteric arteries of spontaneously hypertensive rats (SHR) was investigated by comparing membrane potential changes in response to adrenergic agonists in preparations from female SHR, Wistar-Kyoto (WKY) and normotensive Wistar rats (NWR).2 Resting membrane potential was found to be less negative in mesenteric arteries from SHR than in those from NWR and WKY. Apamin induced a decrease in the membrane potential of mesenteric artery rings without endothelium from NWR and WKY, but had no effects in those from SHR. Both UK 14,304 and adrenaline, in the presence of prazosin, induced a hyperpolarization that was significantly lower in de-endothelialized mesenteric rings from SHR than in those from NWR and WKY. in mesenteric rings with endothelium, however, similar hyperpolarization was observed in the three strains.3 in NWR mesenteric rings with endothelium the hyperpolarization induced by activation of alpha(2)-adrenoceptors was abolished by apamin, whereas in ...
1. The properties of isolated 150-μm mesenteric resistance vessels from chemically denervated 5-month spontaneously hypertensive and normotensive Wistar-Kyoto rats have been examined.. 2. Chemical denervation reduced the blood pressure of both strains of rats, but the denervated spontaneously hypertensive rats were still hypertensive with respect to their denervated Wistar-Kyoto controls.. 3. Chemical denervation did not affect the morphological characteristics or calcium sensitivity of the resistance vessels.. 4. The results suggest that the media hypertrophy and increased calcium sensitivity seen in resistance vessels from non-denervated spontaneously hypertensive rats are intrinsic defects unrelated to either blood pressure or neurogenic influences. ...
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Downregulation of L-type Ca2+ channel in rat mesenteric arteries leads to loss of smooth muscle contractile phenotype and inward hypertrophic ...
article{b05afb58-252f-4a27-a2c1-eeed80e365a7, author = {Möller, Sebastian and Uddman, Erik and Welsh, Nicola and Edvinsson, Lars and Adner, Mikael}, issn = {1879-0712}, language = {eng}, number = {2-3}, pages = {209--215}, publisher = {Elsevier}, series = {European Journal of Pharmacology}, title = {Analysis of the time course for organ culture-induced endothelin ET(B) receptor upregulation in rat mesenteric arteries.}, url = {http://dx.doi.org/10.1016/S0014-2999(02)02499-8}, volume = {454}, year = {2002 ...
Methods Rat mesenteric arteries were mounted in a wire myograph and pre-constricted with U46619; cumulative concentration response curves were then constructed for the vasodilator responses to DHA (100 nM-30 µM). Blockade of NO PGI2 and endothelium dependent hyperpolarization (EDH) vasodilator pathways on DHA induced relation were assessed using pharmacological blockade. The effect of DHA on endothelium-dependent and independent relaxation produced by ACh and NONOate, respectively, was also assessed.. ...
Evidence is provided for expression and a functional role for phosphodiesterase type V (PDE-V) in the rat isolated small mesenteric artery. The reverse transcription polymerase chain reaction (RT--PCR) demonstrated mRNA for PDE-V, while Western blotting and immunocytochemical studies showed corresponding protein expression. Smooth muscle relaxation to the nitric oxide donor, diethylamine NONOate (DEA NONOate; 1 nM - 10 microM; pEC(50)=6.7+/-0.3) was potentiated significantly by the specific inhibitor of PDE-V, 4-[[3,4-(methylenedioxy)benzyl]amino]-6-chloroquinazoline (MBCQ; 1 microM; pEC(50)=10.5+/-0.04). These data show that PDE-V is expressed in both the smooth muscle and endothelial cells of a resistance artery, and the enzyme can significantly influence nitric oxide-evoked vasorelaxation.
Vascular thiol redox state has been shown to modulate vasodilator functions in large conductance Ca2+-activated K+ channels and other related channels. However, the role of vascular redox in small resistance arteries is unknown. To determine how in vivo modulation of thiol redox state affects small resistance arteries relaxation, we generated a transgenic mouse strain that overexpresses thioredoxin, a small redox protein (Trx-Tg), and another strain that is thioredoxin-deficient (dnTrx-Tg). The redox state of the mesenteric arteries (MAs) in Trx-Tg mice is found to be predominantly in reduced state; in contrast, MAs from dnTrx-Tg mice remain in oxidized state. Thus, we created an in vivo redox system of mice and isolated the second-order branches of the main superior MAs from wild-type, Trx-Tg, or dnTrx-Tg mice to assess endothelium-dependent relaxing responses in a wire myograph. In MAs isolated from Trx-Tg mice, we observed an enhanced intermediate-conductance Ca2+-activated potassium channel ...
Ligating to induce ischemia: ligate the feeding branch of the anterior mesenteric artery and the corresponding vein simultaneously with a snare created by 2-0 silk suture or polyethylene tube for 10 min. Both artery and vein were ligated to stop blood supply and induce venule congestion to enhance ischemia.Sham-operated rats without I/R were used as control ...
Rho-kinase expression was investigated in the rat mesenteric artery and the effects of its inhibitors, (+)-(R)-trans-4-(1-aminoethyl)-N(4-pyridyl) cyclohexanecarboxamide dihydrochloride monohydrate (Y-27632) and fasudil (HA-1077), were examined on the increase in perfusion pressure induced by two different receptor agonists, namely the alpha-adrenoceptor agonist, phenylephrine and, the endothelin ETA and ETB receptor agonist, endothelin-1. Y-27632 and fasudil produced a concentration-dependent decrease in perfusion pressure. There was no difference between the concentration -response lines of these two inhibitors. The maximum decrease in the perfusion pressure induced by 10(-5) M Y-27632 was 85.8 +/- 3.7% when the tone was increased by phenylephrine. However, it was 48.1 +/- 5.4% ( ...
Video articles in JoVE about mesenteric artery superior include Assessing Myogenic Response and Vasoactivity In Resistance Mesenteric Arteries Using Pressure Myography.
TY - JOUR. T1 - Endothelial cell facilitation of longitudinal spreading hyperpolarization and dilatation in rat isolated mesenteric artery. AU - Takano, H. AU - Dora, K A. AU - Garland, C J. PY - 2003. Y1 - 2003. M3 - Article. VL - 547P. SP - C109. JO - Journal of Physiology and Pharmacology. JF - Journal of Physiology and Pharmacology. SN - 0867-5910. ER - ...
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Affiliation:筑波大学,基礎医学系,講師, Research Field:General pharmacology,血管生物学, Keywords:エンドセリン,腸管膜動脈,神経ペプチド,血管拡張神経,冠血管,mesenteric artery,血管内皮細胞,CGRP,脳脊髄液,骨格筋, # of Research Projects:4, # of Research Products:0
TY - JOUR. T1 - Endothelial dysfunction in rat mesenteric resistance artery after transient middle cerebral artery occlusion. AU - Martinez-Revelles, Sonia. AU - Jiménez-Altayó, Francesc. AU - Caracuel, Laura. AU - Pérez-Asensio, Fernando J.. AU - Planas, Anna M.. AU - Vila, Elisabet. PY - 2008/1/1. Y1 - 2008/1/1. N2 - Stroke triggers a local and systemic inflammatory response leading to the production of cytokines that can influence blood vessel reactivity. In this study, we aimed to assess whether cerebral ischemia/reperfusion could affect vasoconstriction and vasodilatation on mesenteric resistance arteries (MRA) from Wistar Kyoto rats. The right middle cerebral artery was occluded (90 min) and reperfused (24 h). Sham-operated animals were used as controls. Plasma levels of interleukin (IL)-6 and IL-1β were measured at 24 h. Vasoconstrictor and vasodilator responses were recorded in a wire myograph. Protein expression was determined by Western blot and immunofluorescence, and superoxide ...
TY - JOUR. T1 - The contribution of d-tubocurarine-sensitive and Apamin-sensitive K-channels to EDHF-mediated Relaxation of Mesenteric Arteries from eNOS-/- Mice. AU - Chen, Xiaoliang. AU - Li, Yang. AU - Hollenberg, Morley. AU - Triggle, Christopher. AU - Ding, Hong. PY - 2012/5. Y1 - 2012/5. N2 - The nature of the potassium channels involved in determining endothelium-derived hyperpolarizing factor-mediated relaxation was investigated in first-order small mesenteric arteries from male endothelial nitric oxide synthase (eNOS-/-)-knockout and control (+/+) mice. Acetylcholine-induced endothelium-dependent relaxation of small mesenteric arteries of eNOS-/- was resistant to N-nitro-L-arginine and indomethacin and the guanylyl cyclase inhibitor, 1H-(1,2,4) oxadiazolo (4,3-a) quinoxalin-1-one. Apamin and the combination of apamin and iberiotoxin or apamin and charybdotoxin induced a transient endothelium-dependent contraction of small mesenteric arteries from both eNOS-/- and +/+ mice. ...
Increasing evidence shows that sex hormones exert a protective effect on the vasculature, especially in the regulation of the active vasomotor responses. However, whether sex hormones affect vascular remodelling is currently unclear. In the present study, we tested the hypothesis that testosterone in males and β-oestradiol in females prevent inward remodelling, possibly through inhibition of cross-linking activity induced by enzymes of the TG (transglutaminase) family. Small mesenteric arteries were isolated from male and female Wistar rats. Dose-dependent relaxation to testosterone and β-oestradiol was inhibited by the NO synthase inhibitor L-NAME (NG-nitro-L-arginine methyl ester), confirming that these hormones induce NO release. When arteries were cannulated, pressurized and kept in organ culture with ET-1 (endothelin-1) for 3 days we observed strong vasoconstriction and inward remodelling. Remodelling was significantly inhibited by testosterone in males, and by β-oestradiol in females. ...
Many studies in recent years have implicated an altered microvascular structure in the genesis and maintenance of hypertension.4 5 6 7 8 9 10 11 In the present study we have provided further evidence that resistance arteries from genetically hypertensive rats have a reduced internal diameter compared with arteries from their normotensive controls. In order to do this, we used a pressure myograph. This technique has the advantage that it allows arteries to assume the stereological conformation they would attain in vivo,12 13 in contrast to some other methodologies used for examining resistance artery structure, such as wire myography.13 The media-to-lumen ratio of resistance arteries from DI/H rats was increased compared with DI/N controls. Although this could be taken as evidence for vascular growth, there was no difference in media cross-sectional surface area in arteries from DI/N and DI/H rats. Our results suggest, therefore, that the architecture of the mesenteric vasculature in DI/H rats ...
The novel findings of the present investigation in pressurized rat resistance mesenteric arteries with endothelium include the following: (1) raloxifene at therapeutically achievable concentrations reduces myogenic constriction in a concentration-dependent manner; (2) dilatations to raloxifene are rapid and nongenomic in nature, unrelated to ICI 182,780-sensitive estrogen receptor; (3) endothelium-derived NO accounts in large part for raloxifene-induced dilatations, as they are inhibited by l-NAME; (4) eNOS activation is causally controlled by Ca2+ influx stimulated by raloxifene without involving PI3K/Akt-related mechanisms; (5) raloxifene dose not modulate CTX/apamin-sensitive endothelium-derived hyperpolarizing factor-mediated dilatations; and (6) there is a marked gender difference in dilator responses to raloxifene, which is more effective on female arteries. The present study has provided the first line of experimental evidence exhibiting a potent vasodilating effect of raloxifene in ...
The objective of this study was to evaluate the changes in vascular reactivity of mesenteric arteries resulting from hyperbaric oxygen treatment. It was hypothesized that hyperbaric oxygen treatment alters vascular reactivity in mesenteric arteries due to enhanced production of ATP resulting in significantly larger responses to vasoactive stimuli. All arteries were dissected from porcine mesenteries and placed in Krebs- Henseleit solution. Arteries were initially mounted in isolated organ baths and passively loaded with tensions ranging from 1 to 25 grams at odd intervals to ascertain the optimal passive tension for studying mesenteric arteries. Following a 1-hour equilibration in Krebs-Henseleit solution, arteries were treated with potassium chloride (a nonreceptormediated vasoconstrictor; KCl; 15 - 60 mM) to assess vascular reactivity. Following determination of the optimal passive tension, additional arteries were dissected and tested for viability with KCl. Viable arteries were then subjected to a 2
Trykk myography brukes til å vurdere vasoactivity av små arterier som utvikler vedvarende innsnevring når trykk. Dette manuskriptet...
Yamawaki H, Sato K, Hori M, Ozaki H, Nakamura S, Nakayama H, Doi K, Karaki H. Impairment of EDR by a long-term PDGF treatment in organ-cultured rabbit mesenteric artery. Am J Physiol. 1999 07; 277(1):H318-23 ...
TY - JOUR. T1 - Gender differences in the effect of age on electrical field stimulation (EFS)-induced adrenergic vasoconstriction in rat mesenteric resistance arteries. AU - Sullivan, Jennifer C. AU - Davison, Cathy A.. PY - 2001/3/14. Y1 - 2001/3/14. N2 - The objective of this study was to examine the effects of gender and age on electrical field stimulation (EFS)-induced vasoconstriction. Fisher 344 rats were studied: young females (YF, n = 38), young males (YM, n = 29), old females (OF, n = 33), and old males (OM, n = 30). Isolated mesenteric resistance arteries (endothelium-intact or denuded) were pressurized, and outer diameter was monitored. Dose-response curves were performed to KCl and phenylephrine (PE). EFS (0.1-16 Hz) responses were expressed as percentage of constriction from baseline. Area under the curve (AUC) was calculated and comparisons were made using analysis of variance and t tests. Females became less responsive to EFS-induced constriction with age, whereas constrictor ...
Transient receptor potential (TRP) channels contribute to endothelial cytosolic calcium signaling. Roles for both transient receptor potential C3 (TRPC3) and vallinoid type4 (TRPV4) in agonist-evoked endothelium-dependent vascular relaxation have been proposed. Thus, in this study we have investigated the functional contribution of these channels to endothelium-dependent modulation of phenylephrine- and nerve-evoked increases in tone and to acetylcholine-evoked relaxation in rat mesenteric arteries. Using an immunohistochemical approach, TRPC3 and TRPV4 antibodies showed low level diffuse and punctate labeling in endothelial cells and absence in smooth muscle cells. 1-[4- [(2,3,3-Trichloro-1-oxo-2-propen-1-yl)amino]phenyl]-5- (trifluoromethyl)-1H-pyrazole-4-carboxylic acid (Pyr3), a selective inhibitor of TRPC3 channels enhanced nerve- and phenylephrine-induced increases in tone in endotheliumintact arteries but was without effect on acetylcholine-evoked relaxations. 1-(4-chloro-2-nitrophenyl) sulfonyl
In rat mesenteric arteries, the ability of ACh to evoke hyperpolarization of smooth muscle cells and consummate dilatation relies on an increase in endothelial cell cytosolic free [Ca2+] and activation of Ca2+-activated K+ channels (KCa). The time course of average and spatially organized rises in endothelial cell [Ca2+]i and concomitant effects on membrane potential were investigated in individual cells of pressurized arteries and isolated sheets of native cells stimulated with ACh. In both cases, ACh stimulated a sustained and oscillating rise in endothelial cell [Ca2+]i. Overall, the oscillations remained asynchronous between cells, yet occasionally localized intercellular coordination became evident. In pressurized arteries, repetitive waves of Ca2+ moved longitudinally across endothelial cells, and depended on Ca2+-store refilling. The rise in endothelial cell Ca2+ was associated with sustained hyperpolarization of endothelial cells in both preparations. This hyperpolarization was also evident when
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In rats with chronic neurogenic hypertension induced by sinoaortic baroreceptors denervation (SAD), dl-[3H]norepinephrine (dl-[3H]NE) release, metabolism and vascular response to nerve stimulation were studied in isolated perfused mesenteric arteries. Thirty weeks after SAD, systolic arterial pressure was increased and, in isolated mesenteric arteries, vascular resistance, vascular response to nerve stimulation and responses to exogenous NE were higher in hypertensive than in sham-operated normotensive rats. However, in the isolated mesenteric arteries labeled with dl-[3H]NE, the total increase in radioactivity elicited by nerve stimulation was similar in both SAD and sham-operated groups. Unmetabolized [3H]NE released in mesenteric arteries was higher than that observed in other peripheral noradrenergic tissues (such as cat nictitating membrane, cat spleen, guinea-pig atria) and deaminated glycol 3,4-dihydroxyphenylglycol was the main metabolite of [3H]NE released by nerve stimulation from the ...
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n either of two arteries arising from the aorta and passing between the two layers of the mesentery to the intestine: a) one that arises just above the bifurcation of the abdominal aorta into the common iliac arteries and supplies the left half…
Learn about diseases of the arteries to the kidneys and intestines, including diagnostic tests, and minimally invasive and traditional surgery treatments.
Results: Intrathecal injection of TRPV1 shRNA (6 μg kg−1 per day) for 3 days increased systolic blood pressure and MAP when compared to rats that received control shRNA (control shRNA: 112±2 vs TRPV1 shRNA: 123±2 mmHg). TRPV1 expression was suppressed in T8-L3 segments of dorsal horn and DRG as well as mesenteric arteries of rats given TRPV1 shRNA. Contents of tyrosine hydroxylase, a marker of sympathetic nerves, were increased in mesenteric arteries of rats treated with TRPV1 shRNA. Pretreatment with the 1-adrenoceptor blocker, prazosin (1 mg/kg/day, p.o.), abolished the TRPV1 shRNA-induced pressor effects ...
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Small artery function 2 years postpartum in women with altered glycaemic distributions in their preceding pregnancy Academic Article ...
In this study, our aims were to investigate transient receptor potential melastatin-8 channels (TRPM8) involvement in rotundifolone induced relaxation in the mesenteric artery and to increase the understanding of the role of these thermosensitive TRP channels in vascular tissue. Thus, message and protein levels of TRPM8 were measured by semi-quantitative PCR and western blotting in superior mesenteric arteries from 12 week-old Spague-Dawley (SD) rats. Isometric tension recordings evaluated the relaxant response in mesenteric rings were also performed. Additionally, the intracellular Ca2+ changes in mesenteric artery myocytes were measured using confocal microscopy. Using PCR and western blotting, both TRPM8 channel mRNA and protein expression was measured in SD rat mesenteric artery. Rotundifolone and menthol induced relaxation in the isolated superior mesenteric artery from SD rats and improved the relaxant response induced by cool temperatures. Also, this monoterpene induced an increase in transient
TY - JOUR. T1 - Inducible nitric oxide synthase-derived superoxide contributes to hypereactivity in small mesenteric arteries from a rat model of chronic heart failure. AU - Miller, A A. AU - Megson, I L. AU - Gray, G A. PY - 2000. Y1 - 2000. N2 - The aims of this study were to (a) determine whether inducible nitric oxide synthase (iNOS) is expressed in small mesenteric arteries from rats with chronic heart failure (CHF), (b) investigate the functional significance of this potential source of nitric oxide (NO) on vascular responsiveness and (c) investigate the role that superoxide plays in modulating vascular function in these arteries. CHF was induced in male Wistar rats by coronary artery ligation (CAL). In sham-operated rats the ligature was not tied but pulled under the artery. Six weeks after surgery CAL rats had left ventricular (LV) infarctions and elevated LV end-diastolic pressures. Immunoreactive iNOS was found in endothelial cells, vascular smooth muscle cells and in the adventitia of ...
The superior mesenteric artery is a major blood vessel in the digestive system. This artery branches off the abdominal aorta and supplies oxygenated blood to the pancreas and the lower parts of the intestine. This includes the lower duodenum, as well as transverse colon.
New pharmacotherapies are required to improve vessel graft protection and prevent vasoconstriction and spasm in CABG surgery. Previously we have studied adenosine (A) and lidocaine (L) relaxation in rat aortic rings, and reported a possible crosstalk between L relaxation and adenosine A(2a) receptor inhibition. The aim of the present study was to examine the effect of AL combination compared to A and L alone on relaxation in intact and denuded rat aortic rings and in guinea-pig pressurized mesenteric arterial segments. Aortic rings were harvested from Sprague-Dawley rats and equilibrated in an organ bath containing modified Krebs-Henseleit (KH) solution, pH 7.4, 37 degrees C. Rings were pre-contracted sub-maximally with 0.3 mu M norepinephrine, and the effects of increasing AL, A or L (up to 1.0 mM) were examined in intact and denuded rings. Mesenteric artery segments were isolated from guinea-pigs and mounted in an arteriograph containing KH solution and pressurised to 60 mmHg. Arteries were ...
Retrograde superior mesenteric artery stenting (ROMS) represents a significant development in the treatment of acute mesenteric ischemia. Compared to traditional surgical mesenteric bypass, ROMS is a less invasive technique that avoids many complicat
Approach and Results-Real-time polymerase chain reaction, immunohistochemistry, and Western analyses supported the synthesis and expression of chemerin in perivascular adipose tissue, whereas the primary chemerin receptor ChemR23 was expressed both in the tunica media and endothelial layer. The ChemR23 agonist chemerin-9 caused receptor, concentration-dependent contraction in the isolated rat thoracic aorta, superior mesenteric artery, and mesenteric resistance artery, and contraction was significantly amplified (more than 100%) when nitric oxide synthase was inhibited and the endothelial cell mechanically removed or tone was placed on the arteries. The novel ChemR23 antagonist CCX832 inhibited phenylephrine-induced and prostaglandin F2α-induced contraction (+perivascular adipose tissue), suggesting that endogenous chemerin contributes to contraction. Arteries from animals with dysfunctional endothelium (obese or hypertensive) demonstrated a pronounced contraction to chemerin-9. Finally, ...
The inferior mesenteric artery (IMA) brings oxygen-rich blood to the large intestine, specifically to the upper region of the rectum and the left colic flexure, a bend at the intestines left side. The upper part of the rectum should not be confused with the anus itself.
Inferior mesenteric artery angiogram (bottom image) and subsequent venous phase image (top image)demonstrates pooling of contrast material in the splenic flexur
In the current study, we found that type 2 diabetes impaired the ability of mesenteric arteries to remodel and improve NO-dependent dilation in response to a chronic increase in blood flow. Indeed, AGEs and RAGEs were overexpressed, whereas eNOS level and MMP activity were reduced in arteries from ZDF rats. Ongoing treatment with the AGE-breaker ALT-711 restored the ability of mesenteric arteries from ZDF rats to increase their diameter and improved endothelium-dependent dilation in response to a chronic rise in blood flow.. Physiologically, a chronic rise in blood flow in resistance arteries enlarges vascular diameter and improves endothelium-dependent dilation (9,19,34). This remodeling is essential to adjust organ perfusion during physiological processes, such as development (35), pregnancy (36), or exercise training (37), as well as during pathological processes (mainly ischemic diseases). A similar remodeling also occurs in response to vasodilator treatments (38,39). This remodeling plays a ...
The Arteriograph is a diagnostic instrument which is able to measure the severity of arteriosclerosis. This is the condition of arterial blockage caused by inflammation or damage within arteries followed by an over production of a compound known as plaque created by the body to repair the damage. Plaque is made up of cholesterol, minerals such as calcium, specialised red blood cells known as platelets and other clotting factors. The Arteriograph is a simple and painless, non invasive investigation that can diagnose arteriosclerosis at an early stage . Symptoms of arterial blockage include chest pain from blocking heart arteries, or the loss of sensation, numbness, or cramp in the lower limbs as the leg arteries block. These symptoms tend not to occur until a considerable amount of an artery is blocked and other arteries are no longer able to offer effective collateral circulation. Symptoms of cardiovascular disease leading to heart attacks and strokes usually appear only in the last and late ...
A 56--year-old man pre-sented -with com-plete occlu-sion of the -superior and infe-rior mes-en-teric -arteries -resulting in -chronic mes-en-teric -ischemia. -After a min-imal angio-plasty a Wall-stent was -inserted -across the -superior mes-en-teric -artery occlu-sion. -This pro-duced imme-diate clin-ical -relief, -with a suc-cessful angio-graphic -result. -Eight -months -later, an intra-stent occlu-sion -with -acute -bowel infarc-tion was -treated in emer-gency by saph-e-nous -vein -bypass -graft. -Despite the -death of the -patient a few -days -later -from a -multivis-ceral -failure syn-drome, -this -method -seemed to us fea-sible in -treating a chron-i-cally -occluded SMA in -patients -with -high oper-a-tive -risk.. ...
Details of the image Enlarged arc of Riolan and marginal artery of Drummond secondary to occluded coeliac axis and superior mesenteric artery Modality: CT (C+ arterial phase)
The pharmacological effects on the cardiovascular system of yangambin, a lignan isolated from Ocotea duckei Vattimo (Lauraceae), were studied in rats using combined functional and biochemical approaches. In non-anaesthetized rats, yangambin (1, 5, 10, 20, 30 mg/kg, i.v.) induced hypotension (−3.5 ± 0.2; −7.1 ± 0.8; −8.9 ± 1.3; −14 ± 2.3, −25.5% ± 2.6%, respectively) accompanied by tachycardia (5.9 ± 0.5; 5.9 ± 1.6; 8.8 ± 1.4; 11.6, 18.8% ± 3.4%, respectively). In isolated rat atria, yangambin (0.1 µM-1 mM) had very slight negative inotropic (Emax = 35.6% ± 6.4%) and chronotropic effects (Emax = 10.2% ± 2.9%). In endothelium-intact rat mesenteric artery, yangambin (0.1 µM-1 mM) induced concentration-dependent relaxation (pD2 = 4.5 ± 0.06) of contractions induced by phenylephrine and this effect was not affected by removal of the endothelium. Interestingly, like nifedipine, the relaxant effect induced by yangambin was more potent on the contractile response induced by KCl 80 mM
Vascular Disturbances A frequent misconception, despite abundant experience to the contrary, is that pain associated with intraabdominal vascular disturbances is sudden and catastrophic in nature. The pain of embolism or thrombosis of the superior mesenteric artery or that of impending rupture of an abdominal aortic aneurysm certainly may be severe and diffuse. Yet, just as frequently, the patient with occlusion of the superior mesenteric artery has only mild continuous diffuse pain for 2 or 3 days before vascular collapse or findings of peritoneal inflammation appear. ...
A review of the clinical presentation and sonographic diagnosis of mesenteric artery ischemia. Mesenteric artery insufficiency, Other mesenteric pathologies, Stents, Surgical management.
J Pediatr Orthop. 2018 Apr 17.. Spontaneous and isolated dissection of the superior mesenteric artery: proposal of a management algorithm. ROUSSEL A, PELLENC Q, CERCEAU P, TRESSON P, HOUBBALAH R, FRANCIS F, PARASKEVAS N, LESECHE G, CORCOS O, PASI N, CASTIER Y ...
Sigma-Aldrich offers abstracts and full-text articles by [Xianming Su, Xiaowen Zhi, Ting Cui, Qiaowei Zheng, Shixiang Wang, Yongxiao Cao, Changcong Cui, Weiyi Feng].
Results: Intrathecal injection of TRPV1 shRNA (6 μg kg−1 per day) for 3 days increased systolic blood pressure and MAP when compared to rats that received control shRNA (control shRNA: 112±2 vs TRPV1 shRNA: 123±2 mmHg). TRPV1 expression was suppressed in T8-L3 segments of dorsal horn and DRG as well as mesenteric arteries of rats given TRPV1 shRNA. Contents of tyrosine hydroxylase, a marker of sympathetic nerves, were increased in mesenteric arteries of rats treated with TRPV1 shRNA. Pretreatment with the 1-adrenoceptor blocker, prazosin (1 mg/kg/day, p.o.), abolished the TRPV1 shRNA-induced pressor effects ...
Free, official coding info for 2018 ICD-10-CM S35.291A - includes detailed rules, notes, synonyms, ICD-9-CM conversion, index and annotation crosswalks, DRG grouping and more.
Telezhkin, V. S., Yarova, P. L., Garland, C. J. and Dora, K. A., 2007. Isolated endothelial cells from rat mesenteric artery display spontaneous outward currents. In: The Physiological Society Meeting: Ion Channels and the Microcirculation ...
Inducible change in the behavior of resistance arteries from circulating factor in preeclampsia: an effect specific to myometrial vessels from pregnant women
An organs larger arteries and veins flow between its functional units. Often there is a generous amount of loose fibrous tissue separating an artery and the business cells of the organ. If youre interested in the layers of the arteries, they are: Intima: Inner layer, the endothelium, a bit of collagen, and perhaps a few other inconspicuous cells. Media: Middle layer, composed of smooth muscle oriented circumferentially. Adventitia: Fibrous tissue, merging with the surrounding fibrous tissue of the organ. ...
"Superior mesenteric artery syndrome , Radiology Reference Article , Radiopaedia.org". Radiopaedia. Retrieved 2020-11-11. Rueff ... However, the main causes are: Annular pancreas Adhesions Systemic sclerosis Superior mesenteric artery syndrome Aneurysm. ...
Opie, EL; Lynch, CJ; Tershakovec, M (April 1970). "Sclerosis of the mesenteric arteries of rats. Its relation to longevity and ...
Kornmehl, P.; Weizman, Z.; Liss, Z.; Bar-Ziv, J.; Joseph, A. (1988). "Superior mesenteric artery syndrome presenting as an ... It was subsequently proven to be MNGIE superior mesenteric artery syndrome (SMA syndrome) "is a gastrointestinal disorder ... "Superior Mesenteric Artery Syndrome". Digestive Surgery. 26 (3): 213-214. doi:10.1159/000219330. PMID 19468230. ... by the compression of the third or transverse portion of the duodenum against the aorta by the superior mesenteric artery ...
Anorexia nervosa Conatus , Wiktionary Metabolism Starvation Superior mesenteric artery syndrome Wasting "Metabolic Pathways , ...
Busquet J (1997). "Intravascular stenting in the superior mesenteric artery for chronic abdominal angina". Journal of ... "Transient relief of abdominal angina by Wallstent placement into an occluded superior mesenteric artery". The Journal of ... Abdominal pain Ischemic colitis Kapadia S, Parakh R, Grover T, Agarwal S (2005). "Side-to-side aorto-mesenteric anastomosis for ... a type of chest pain due to obstruction of the coronary artery), angina by itself can also mean "any spasmodic, choking, or ...
"Mechanism of the vasodilator effect of Euxanthone in rat small mesenteric arteries". Phytomedicine. 17 (8-9): 690-692. doi: ...
The rectum receives blood from both the inferior mesenteric artery and the internal iliac artery; the rectum is rarely involved ... The colon receives blood from both the superior and inferior mesenteric arteries. The blood supply from these two major ... In a 1991 review concerning 2137 patients the accidental inferior mesenteric artery ligation was the most common cause (74%) of ... The complication can be prevented through careful selection of subjects that may require replanting inferior mesenteric artery ...
This antagonistic activity was responsible for the ability of 12(S)-HETE and 12(R)-HETE to relax mouse mesenteric arteries pre- ... 12(S)-HETE and 12(S)-HpETE stimulate the dilation of rat mesenteric arteries; 12(S)-HETE stimulates the dilation of coronary ... The vasodilating effect on mouse mesenteric arteries appears due to 12S-HETE's ability to act as a Thromboxane receptor ... "Impaired arachidonic acid-mediated dilation of small mesenteric arteries in Zucker diabetic fatty rats". AJP: Heart and ...
Because of collateral blood flow from the superior mesenteric artery (SMA) via the marginal artery, the inferior mesenteric ... from the left subclavian to below the renal artery; Extent III, from the sixth intercostal space to below the renal artery; and ... extending from the left subclavian artery to just below the renal artery; Extent II, ... Disease of the aorta proximal to the left subclavian artery in the chest lies within the specialty of cardiac surgery, and is ...
... it receives dual blood supply from the terminal branches of the superior mesenteric artery and the inferior mesenteric artery, ... It receives blood supply from the superior mesenteric artery. The left colic flexure or splenic flexure (as it is close to the ...
... celiac artery) and superior mesenteric artery, passes behind the pancreas, and enters the upper part of the mesentery, ... and duodenojejunal flexure to connective tissue surrounding the superior mesenteric artery and coeliac artery. It is also known ... Superior mesenteric artery syndrome is a rare abnormality caused by a congenitally short suspensory muscle. The duodenum and ... Superior mesenteric artery syndrome (SMA) is an extremely rare life-threatening condition that can either be congenital and ...
The jejunum and ileum receive blood from the superior mesenteric artery.[14] Branches of the superior mesenteric artery form a ... Embolus or thrombus of the superior mesenteric artery or the superior mesenteric vein ... via the superior pancreaticoduodenal artery and from the superior mesenteric artery via the inferior pancreaticoduodenal artery ... The small intestine receives a blood supply from the celiac trunk and the superior mesenteric artery. These are both branches ...
Lymph from the midgut drains to prevertebral superior mesenteric nodes located at the origin of the superior mesenteric artery ... After it bends around the superior mesenteric artery, it is called the "midgut loop". It comprises the portion of the ... Arterial supply to the midgut is from the superior mesenteric artery, an unpaired branch of the aorta. Venous drainage is to ... Parasympathetic innervation of the midgut is from the superior mesenteric plexus, while sympathetic innervation is from the ...
Arterial supply to the colon comes from branches of the superior mesenteric artery (SMA) and inferior mesenteric artery (IMA). ... a branch of the superior mesenteric artery (SMA), while the latter third is supplied by branches of the inferior mesenteric ... A literature survey of the connection(s) between the superior and inferior mesenteric arteries". Am J Surg. 193 (6): 742-748. ... Historically, a structure variously identified as the arc of Riolan or meandering mesenteric artery (of Moskowitz) was thought ...
Other lymph nodes in the abdomen are associated with the superior and inferior mesenteric arteries. The celiac lymph nodes are ... The celiac lymph nodes are associated with the branches of the celiac artery. ...
"Receptors for insulin-like growth factor-I in plasma membranes isolated from bovine mesenteric arteries". Acta Endocrinologica ...
Inferior Mesenteric Artery at The Anatomy Lesson by Wesley Norman (Georgetown University) Anatomy portal. ... Lumbar splanchnic nerves provide sympathetic innervation via the inferior mesenteric ganglion. Behind the sigmoid colon are the ...
The arcades are anastomoses of the jejunal and ileal arteries, branches of superior mesenteric artery. The vasa recta of the ... Intestinal arteries Loop of small intestine showing distribution of intestinal arteries. jejunumileum at The Anatomy Lesson by ... For the kidney structure, see straight arterioles of kidney Vasa recta are straight arteries coming off from arcades in the ...
"Splenic infarction complicating percutaneous transluminal coeliac artery stenting for chronic mesenteric ischaemia: a case ... Splenic infarction occurs when the splenic artery or one of its branches are occluded, for example by a blood clot. In one ... Examples include abdominal traumas, aortic dissection, torsion of the splenic artery (for example, in wandering spleen) or ... Any factor that directly compromises the splenic artery can cause infarction. ...
Complications may include seizures, disseminated intravascular coagulopathy, mesenteric artery occlusion, or rhabdomyolysis. ...
Infections and conditions associated with wasting include tuberculosis, chronic diarrhea, AIDS, and superior mesenteric artery ... Anorexia Atrophy Cachexia Superior mesenteric artery syndrome Weight loss United Nations Children's Fund, World Health ...
... cannulated mesenteric arteries show reduced flow-induced (or "shear stress" induced) dilation. PTPmu tyrosine phosphatase ... "Impaired flow-induced dilation in mesenteric resistance arteries from receptor protein tyrosine phosphatase-mu-deficient mice ... endothelial cells in capillaries and arteries throughout the body, and in retinal and brain cells. PTPmu has been shown to ... of PTPµ expression in animal tissues have demonstrated that PTPµ is preferentially expressed in endothelial cells of arteries ...
... is a known risk factor for the development of Superior mesenteric artery syndrome. Visceroptosis also is known as ...
In rat mesenteric artery, KCNE4 augments KCNQ4 channel activity to regulate arterial tone. A single polymorphism in the KCNE4 ... KCNE4 has no known effect on KCNQ2, KCNQ3 or KCNQ5 channels, but augments activity of KCNQ4 in HEK cells, mesenteric artery and ...
Damage to mesenteric arteries can cause abdominal pain, mesenteric ischemia, and bowel perforation. Abdominal pain may also be ... affecting medium-sized muscular arteries, typically involving the arteries of the kidneys and other internal organs but ... Involvement of the renal artery, which supplies the kidneys with highly oxygenated blood, often leads to high blood pressure in ... Cardiovascular System: Involvement of the arteries of the heart may cause a heart attack, heart failure, and inflammation of ...
... and postjunctional level of the canine mesenteric and pulmonary arteries". British Journal of Pharmacology. 124 (6): 1207-1212 ... little known as compared to arteries. All effects of the catecholamines adrenaline, noradrenaline, dopamine and isoprenaline ...
The superior mesenteric plexus includes the superior mesenteric ganglia and is located around the superior mesenteric artery. ... The inferior mesenteric plexus includes the inferior mesenteric ganglia and is located around the inferior mesenteric artery. ... Under the clavicle, the trunks reorganize to form cords (fasciculi) around the axillary artery (arteria axillaris). The lateral ...
... the arterial supply is from the superior mesenteric artery (SMA), and its branch the inferior pancreaticoduodenal artery ... The superior mesenteric artery and vein are anterior to the third part of duodenum. This part may be compressed between the ... The superior and inferior pancreaticoduodenal arteries (from the gastroduodenal artery and SMA respectively) form an ... the arterial supply is from the gastroduodenal artery and its branch the superior pancreaticoduodenal artery. Distal to this ...
Nutcracker syndrome - Compression of the left renal vein between aorta and upper mesenteric artery. Butros SR, Liu R, Oliveira ... Along this course, it goes under the right common iliac artery, which may compress it against the lumbar spine and limit the ... Specifically, the problem is due to left common iliac vein compression by the overlying right common iliac artery. This leads ... There are case reports of the inferior vena cava being compressed by the iliac arteries or right-sided compression syndromes, ...
Gadkari TV, Cortes N, Madrasi K, Tsoukias NM, Joshi MS (November 2013). "Agmatine induced NO dependent rat mesenteric artery ...
... also drained by the superior mesenteric vein) via the inferior mesenteric vein, which drains in the splenic vein shortly before ... It travels above the pancreas, alongside the splenic artery. It collects branches from the stomach and pancreas, and most ... The splenic vein ends in the portal vein, formed when the splenic vein joins the superior mesenteric vein. ...
... mesenteric, and coronary arteries.[8] to cause a reduction in systemic vascular resistance. Fenoldopam has a rapid onset of ... Hughes AD, Sever PS (1989). "Action of fenoldopam, a selective dopamine (DA1) receptor agonist, on isolated human arteries". ...
অন্ত্রধারক বা অন্ত্রাবরক (Mesenteric). *উপান্ত্র (Appendix). *বৃহদন্ত্র (Large intestine). *যকৃৎ (Liver). *পিত্তথলি (Gall ... ধমনী (Artery). *শিরা (Vein). *কৈশিকনালী (Capillary). *লোহিত রক্তকণিকা (Red blood cell). *অণুচক্রিকা (Platelet) ...
Prevention includes the use of breast milk and probiotics.[2] A 2012 policy by the American Academy of Pediatrics recommended feeding preterm infants human milk, finding "significant short- and long-term beneficial effects," including reducing the rate of NEC by a factor of two or more.[10] Small amounts of oral feeds of human milk starting as soon as possible, while the infant is being primarily fed intravenously, primes the immature gut to mature and become ready to receive greater intake by mouth.[11] Human milk from a milk bank or donor can be used if mother's milk is unavailable. The gut mucosal cells do not get enough nourishment from arterial blood supply to stay healthy, especially in very premature infants, where the blood supply is limited due to immature development of the capillaries, so nutrients from the lumen of the gut are needed. A Cochrane review in 2014 found that supplementation of probiotics enterally "prevents severe NEC as well as all-cause mortality in preterm ...
... including mesenteric and tail arteries from rats as well as genital arteries from rabbits. These findings together suggest that ... Although Nitric Oxide (NO) is recognized as the primary factor at level of arteries, increased evidence for the role of another ... In some arteries, eicosanoids and K+ ions may themselves initiate a conducted endothelial hyperpolarization, thus suggesting ... Since EDHF's contribution is greatest at level of small arteries, the changes in the EDHF action are of critical importance for ...
... including the umbilical arteries and vein. The differential vasoconstriction of these fetal vessels compared to the vasodilator ... "Association between kinin B(1) receptor expression and leukocyte trafficking across mouse mesenteric postcapillary venules" ...
The next branch from the abdominal aorta is the superior mesenteric artery, which supplies the regions of the digestive tract ... There are three main divisions - the left gastric artery, the common hepatic artery and the splenic artery. ... The final branch which is important for the digestive system is the inferior mesenteric artery, which supplies the regions of ... The celiac artery is the first major branch from the abdominal aorta, and is the only major artery that nourishes the digestive ...
Testicular artery. শিরা. Testicular vein, Pampiniform plexus. স্নায়ু. Spermatic plexus. লসিকা. Lumbar lymph nodes. ... অন্ত্রধারক বা অন্ত্রাবরক (Mesenteric). *উপান্ত্র (Appendix). *বৃহদন্ত্র (Large intestine). *যকৃৎ (Liver). *পিত্তথলি (Gall ...
Anatomy photo:39:03-0100 at the SUNY Downstate Medical Center - "Branches of Superior Mesenteric Artery" ... Appendicular artery. The appendicular artery (appendiceal artery) is a terminal branch of the ileocolic artery that descends ... Arteries of cecum and appendix (appendicular artery labeled at bottom center right) ... Retrieved from "https://en.wikipedia.org/w/index.php?title=Appendicular_artery&oldid=666118098" ...
Kanoe M, Yamanaka M, Inoue M (1989). "Effects of Fusobacterium necrophorum on the mesenteric microcirculation of guinea pigs". ... blocking branches of the pulmonary artery that carry blood with little oxygen from the right side of the heart to the lungs. ...
Lumbar arteries. Median sacral artery. Visceral branches:. Celiac trunk. Middle suprarenal arteries. Superior mesenteric artery ... and visceral arteries (the celiac trunk, the superior mesenteric artery and the inferior mesenteric artery). It ends in a ... Renal arteries. Gonadal arteries testicular in males, ovarian in females. Inferior mesenteric artery. Terminal branches: Common ... Left subclavian artery. Descending aorta, thoracic part: Left bronchial arteries. esophageal arteries to the thoracic part of ...
ACA (anterior communicating, Recurrent artery of Heubner, Orbitofrontal artery). *MCA (anterolateral central, Prefrontal artery ... The arteries and veins have three layers. The middle layer is thicker in the arteries than it is in the veins: *The inner layer ... In all arteries apart from the pulmonary artery, hemoglobin is highly saturated (95-100%) with oxygen. In all veins apart from ... In general, arteries and arterioles transport oxygenated blood from the lungs to the body and its organs, and veins and venules ...
testicular artery in males. *ovarian artery in females. lumbar[edit]. inferior mesenteric[edit]. *left colic artery *ascending ... internal carotid artery[edit]. *ophthalmic artery *Orbital group *Lacrimal artery *lateral palpebral arteries ... common hepatic artery *proper hepatic artery *Terminal branches *right hepatic artery *Cystic artery ... posterior tibial artery *fibular artery (sometimes from popliteal artery) *communicating branch to the anterior tibial artery ...
... the celiac artery, superior mesenteric artery, and inferior mesenteric artery. The areas supplied by these arteries are used to ... The sac is surrounded by a network of vitelline arteries. Over time, these arteries consolidate into the three main arteries ... From the bifurcation of the trachea downwards, the esophagus passes behind the right pulmonary artery, left main bronchus, and ... The upper parts of the esophagus and the upper esophageal sphincter receive blood from the inferior thyroid artery, the parts ...
This condition is not to be confused with superior mesenteric artery syndrome, which is the compression of the third portion of ... Compression of the left renal vein (marked by the arrow) between the superior mesenteric artery (above) and the aorta (below) ... The legs of this nutcracker, with some imagination, could represent the superior mesenteric artery and abdominal aorta in ... and superior mesenteric artery (SMA), although other variants exist. The name derives from the fact that, in the sagittal plane ...
... superior mesenteric artery syndrome.[124] Delayed stomach emptying, or gastroparesis, often develops following food restriction ...
... of the superior mesenteric artery can be useful in identifying malrotation.[3] ... widening the mesenteric pedicle by separation of the duodenum and cecum.. With this condition the appendix is often on the ... a twisting that can obstruct the mesenteric blood vessels and cause intestinal ischemia). ...
By calculating the frequency shift of a particular sample volume, for example flow in an artery or a jet of blood flow over a ... Compression is used in this ultrasonograph to get closer to the abdominal aorta, making the superior mesenteric vein and the ... Blood velocity can be measured in various blood vessels, such as middle cerebral artery or descending aorta, by relatively ... Ultrasound scanners have different Doppler-techniques to visualize arteries and veins. The most common is colour doppler or ...
... of a branch of the left coronary artery (LCA, right coronary artery = RCA). ... Brain ischemia · Ischaemic heart disease · Ischemic colitis/Mesenteric ischemia. Infarction. general: Anemic infarct · ... 2005). "Effects of antibiotic therapy on outcomes of patients with coronary artery disease: a meta-analysis of randomized ... is not associated with coronary artery disease or retinopathy in type 2 diabetes: the Fremantle Diabetes Study". Aust N Z J Med ...
In the case that the superior mesenteric artery, or another major intestinal artery, is occluded, large segments of bowel can ...
... the celiac artery, superior mesenteric artery, and inferior mesenteric artery. The areas supplied by these arteries are used to ... Artery. Right gastric artery, left gastric artery, right gastro-omental artery, left gastro-omental artery, short gastric ... The sac is surrounded by a network of vitelline arteries. Over time, these arteries consolidate into the three main arteries ... Schematic image of the blood supply to the human stomach: left and right gastric artery, left and right gastroepiploic artery ...
"Effect of estrogen plus progestin on risk for biliary tract surgery in postmenopausal women with coronary artery disease. The ...
... superior mesenteric artery, termination of spinal cord, beginning of filum terminalis, renal vessels, middle suprarenal ... arteries, and hila of kidneys. The fifth lumbar vertebra is characterized by its body being much deeper in front than behind, ...
The smaller arteries and arterioles have higher resistance, and confer the main blood pressure drop across major arteries to ... In the innominate artery, the average reading is 110/70 mmHg, the right subclavian artery averages 120/80 and the abdominal ... The shear stress at the wall that is associated with blood flow through an artery depends on the artery size and geometry and ... Other major arteries have similar levels of blood pressure recordings indicating very low disparities among major arteries. ...
Mesenteric vein thrombosis, which may cause mesenteric ischemia (insufficient blood flow to the intestine) ... Bauersachs RM, Lindhoff-Last E, Ehrly AM: [Ambulatory treatment of an acute pulmonary artery embolism in fresh thigh vein ...
This may be aided by fibrinolytic drugs such as Tissue Plasminogen Activator (tPA) in instances of coronary artery occlusion. ... This means that it is anterograde in veins or retrograde in arteries. ... and travel through the pulmonary artery, resulting in a pulmonary embolism. Arterial thrombosis resulting from hypertension or ... atherosclerosis can become mobile and the resulting emboli can occlude any artery or arteriole downstream of the thrombus ...
... with vessels originating as branches of both the coeliac artery and superior mesenteric artery. The splenic artery runs along ... Artery. Inferior pancreaticoduodenal artery, anterior superior pancreaticoduodenal artery, posterior superior ... The superior mesenteric artery passes down in front of the left half across the uncinate process; the superior mesenteric vein ... which extends to the back of the superior mesenteric vein and ends at the superior mesenteric artery.[5] ...
Major inflammatory lesions in the mesenteric arteries suggested that the worm larvae were ingested and migrated to the kidney.[ ... Infestations of the giant nematode Crassicauda boopis can cause inflammation of the renal arteries and potential kidney failure ...
Micrograph of a mesenteric lymph node with adenocarcinoma. Lymph nodes can be affected by both primary cancers of lymph tissue ...
Superior mesenteric artery Inferior mesenteric artery Gray, Henry (1918). "5a. 2. The Abdominal Aorta". Anatomy of the Human ... Both the superior and inferior mesenteric arteries arise from the abdominal aorta. Each of these arteries travel through the ... branches of these arteries join with the marginal artery of the colon, which means that occlusion of one of the main arteries ... The mesenteric arteries take blood from the aorta and distribute it to a large portion of the gastrointestinal tract. ...
Superior mesenteric artery Dissection showing the anatomical relationship between the superior mesenteric artery and ... This artery is completed by branches of the left colic which is a branch of the inferior mesenteric artery. Compared to other ... Located under this portion of the superior mesenteric artery, between it and the aorta, are the following: left renal vein - ... In human anatomy, the superior mesenteric artery (SMA) arises from the anterior surface of the abdominal aorta, just inferior ...
Mesenteric artery ischemia occurs when there is a narrowing or blockage of one or more of the three major arteries that supply ... mesenteric; Dead gut - mesenteric; Atherosclerosis - mesenteric artery; Hardening of the arteries - mesenteric artery ... Mesenteric artery ischemia occurs when there is a narrowing or blockage of one or more of the three major arteries that supply ... A mesenteric angiogram is a test that involves injecting a special dye into your bloodstream to highlight the arteries of the ...
... artery ischemia and infarction occurs when there is a narrowing or blockage of one or more branches of the major arteries that ... supply the small and large intestines, called the mesenteric arteries. ... called the mesenteric arteries. Narrowing of the arteries occurs when fat, cholesterol, and other substances build up in the ... Mesenteric artery ischemia and infarction occurs when there is a narrowing or blockage of one or more branches of the major ...
... portion of the duodenum between the aorta and the superior mesenteric artery. This results in chronic, intermittent, or acute ... Superior mesenteric artery (SMA) syndrome is an uncommon but well recognized clinical entity characterized by compression of ... encoded search term (Superior Mesenteric Artery (SMA) Syndrome) and Superior Mesenteric Artery (SMA) Syndrome What to Read Next ... Superior Mesenteric Artery (SMA) Syndrome. Updated: Dec 31, 2018 * Author: Frederick Merrill Karrer, MD, FACS; Chief Editor: ...
... Christos Bakoyiannis,1 Ioannis Anastasiou,2 ... Y. J. Park, K. B. Park, D. I. Kim et al., "Natural history of spontaneous isolated superior mesenteric artery dissection ... M. N. Tameo, M. J. Dougherty, and K. D. Calligaro, "Spontaneous dissection with rupture of the superior mesenteric artery from ... T. Nagai, R. Torishima, A. Uchida et al., "Spontaneous dissection of the superior mesenteric artery in four cases treated with ...
Mesenteric artery ischemia is a condition that restricts blood flow to your intestines. Find out what causes it and how to ... What Is Mesenteric Artery Ischemia?. Mesenteric artery ischemia is a condition that restricts blood flow to your intestines. ... What Are the Causes of Mesenteric Artery Ischemia?. People of any age can develop mesenteric artery ischemia (MAI), but its ... What Are the Symptoms of Mesenteric Artery Ischemia?. Mesenteric artery ischemia has two types: acute and chronic. The acute ...
This artery branches off the abdominal aorta and supplies oxygenated blood to the pancreas and the lower parts of the intestine ... The superior mesenteric artery is a major blood vessel in the digestive system. ... Superior mesenteric artery. Superior mesenteric artery. Medically reviewed by the Healthline Medical Network - Written by the ... The superior mesenteric artery is a major blood vessel in the digestive system. This artery branches off the abdominal aorta ...
The Southeastern Surgical Congress owns and publishes The American Surgeon monthly. It is the official journal of the Congress and the Southern California Chapter of the American College of Surgeons, which all members receive each month. The journal brings up to date clinical advances in surgical knowledge in a popular reference format. In addition to publishing papers presented at the annual meetings of the associated organizations, the journal publishes selected unsolicited manuscripts. If you have a manuscript youd like to see published in The American Surgeon select "Information for Authors" from the Related Information options below. A Copyright Release Form must accompany all manuscripts submitted ...
title = {Aneurysm of the superior mesenteric artery}. author = {Gebauer, A}. abstractNote = {This is a report about 4 patients ... Even though an aneurysm of the superior mesenteric artery is rare, it has to be considered in the differential diagnosis of ... Even though an aneurysm of the superior mesenteric artery is rare, it has to be considered in the differential diagnosis of ... This is a report about 4 patients with aneurysms of the superior mesenteric artery of arteriosclerotic, mycotic and probably ...
... of the third portion of the duodenum between the superior mesenteric artery and the aorta defines superior mesenteric artery ... Conclusion: Superior mesenteric artery syndrome determines an acute or chronic intestinal obstruction. Injected abdominal scan ... Aorto-mesenteric space and angle were reduced. At laparotomy internal derivation by duodenojejunostomy was done. Postoperative ... of the third portion of the duodenum between the superior mesenteric artery and the aorta defines superior mesenteric artery ...
Disorder: Superior Mesenteric Artery Syndrome. Superior Mesenteric Artery (SMA) Syndrome. Note: Many disorders can affect the ... Superior mesenteric artery syndrome is a rare digestive system disorder. The superior mesenteric artery […] ...
... Metin Keskin,1 Turgut Akgül,2 Adem ... Superior mesenteric artery syndrome is a rare condition that causes a proximal small intestinal obstruction due to contraction ... Scoliosis surgery is one of the 15 reasons for superior mesenteric artery syndrome, which can present with acute or chronic ... In this paper, we describe a patient who developed superior mesenteric artery syndrome after scoliosis surgery and was treated ...
The superior mesenteric artery is a large blood vessel that supplies oxygen and nutrients to the lower digestive tract. Its ... Superior mesenteric artery syndrome occurs when the duodenum is compressed by a large artery in the abdomen. As a rule, large ... Lastly, an ileocolic artery, the final terminal branch of the superior mesenteric artery, covers whatever remains, including ... The superior mesenteric artery does, however, further branch. An inferior pancreaticoduodenal artery supplies blood to the ...
Superior mesenteric artery syndrome is a rare digestive system disorder. The superior mesenteric artery provides blood to the ... Symptoms occur when the artery obstructs the duodenum.. Superior mesenteric artery syndrome may be referred to at SMA Syndrome ... Superior mesenteric artery syndrome is usually suspected based on signs and symptoms. A diagnosis can be confirmed by imaging ... Superior Mesenteric Artery Syndrome: Medscape Reference (free registration required). Sources:. National Institutes of Health ( ...
The superior mesenteric artery syndrome (SMAS) was first described by Von Rokitansky in 1861 as an obstruction of the third ... Superior mesenteric artery syndrome (SMAS) has been proposed as a rare cause of proximal bowel obstruction resulting from ... Superior mesenteric artery syndrome simulating acute pancreatitis: A case report. Am J Gastroenterol 1976;66:476-9. [ Links ]. ... Superior mesenteric artery syndrome: Spectrum of CT findings with multiplanar reconstructions and 3-D imaging. Abdom Imaging ...
Mesenteric Artery, Superior* / surgery. Middle Aged. Mitral Valve / surgery. Postoperative Complications / etiology. ... CT-scan showed a peripherally located ruptured aneurysm of a branch of the superior mesenteric artery. TREATMENT AND COURSE: ...
Laparoscopy is a safe, effective, and readily available alternative for patients with Superior Mesenteric Artery Syndrome, that ... Laparoscopic Duodenojejunostomy for Superior Mesenteric Artery Syndrome. Introduction:. Laparoscopy has become an invaluable ... This video illustrates the role of laparoscopy for Superior Mesenteric Artery Syndrome. ... hence superior mesenteric artery syndrome. Laparoscopic duodenojejunostomy was performed, highlighting various anatomic ...
Background: Superior mesenteric artery (SMA) injuries are rare and often lethal injuries incurring very high morbidity and ... Multiinstitutional experience with the management of superior mesenteric artery injuries J Am Coll Surg. 2001 Oct;193(4):354-65 ...
Superior Mesenteric Artery Syndrome Following Gastric Bypass. Luke Kinsinger, MD, Isaac Samuel, MD, Jessica Smith, MD, Peter ... She was diagnosed with superior mesenteric artery syndrome and treated with laparoscopic duodeno-jejunostomy with resolution of ...
... mesenteric artery embolism, mesenteric artery thrombosis, non-occlusive mesenteric ischemia, therapy Acute mesenteric artery ... Occlusions in the peripheral part of superior mesenteric artery are treated by means of resection of the affected parts of the ... Der akute Mesenterialarterienverschluss // Acute mesenteric artery occlusion. Journal f r Gastroenterologische und ... In case of occlusion of the central part of superior mesenteric artery embolectomy in combination with resection of the ...
... of retroperitoneal fat has been postulated as a major factor in the cause of the uncommon complication of superior mesenteric ... Superior Mesenteric Artery Syndrome / etiology, metabolism, therapy*. From MEDLINE®/PubMed®, a database of the U.S. National ... 8302259 - Superior mesenteric artery syndrome in a burn patient.. 17763899 - Hemoptysis complicating scimitar syndrome: from ... This case study describes the nutrition management of a burn patient who developed superior mesenteric artery syndrome.. ...
Superior mesenteric artery syndrome with hepatic portal venous gas. Chi-Lun Tsai, Ming-Jenn Chen, Che-Kim Tan, Khee-Siang Chan ... Superior mesenteric artery syndrome with hepatic portal venous gas was diagnosed. This syndrome occurs when the fat pad between ... The superior mesenteric artery syndrome. The disease that isnt, or is it? J Clin Gastroenterol 1985; 7: 113-116. ... 2. Ylinen P, Kinnunen J, Hockerstedt K. Superior mesenteric artery syndrome. A follow-up study of 16 operated patients. J Clin ...
... mesenteric artery superior include Assessing Myogenic Response and Vasoactivity In Resistance Mesenteric Arteries Using ... Mesenteric Artery, Superior: A large vessel supplying the whole length of the small intestine except the superior part of the ... Assessing Myogenic Response and Vasoactivity In Resistance Mesenteric Arteries Using Pressure Myography. Ravirajsinh N. Jadeja1 ... It arises from the anterior surface of the aorta below the celiac artery at the level of the first lumbar vertebra. ...
The Effects Of THC In Rat Mesenteric Vasculature, and Endocannabinoid Anandamide The effects of Δ9-tetrahydrocannabinol in rat ... 2005 June Abstract 1. Δ9-tetrahydrocannabinol (THC) produces varying effects in mesenteric... ... mesenteric vasculature, and its interactions with the endocannabinoid anandamide Saoirse E OSullivan, David A Kendall, and ...
The external iliac arteries are large arteries that connect the femoral arteries to the common iliac arteries. ... ... the inferior mesenteric artery (IMA) with the superior mesenteric artery (SMA). ... ... This artery is completed by branches of the left colic which is a branch of the inferior mesenteric artery. The inferior ... The middle colic artery is a branch of the superior mesenteric artery that mostly supplies the transverse colon. ... The Right ...
In the isolated canine mesenteric artery relaxation caused by nicorandil [N-(2-hydroxyethyl)nicotinamide nitrate ester; SG-75] ... In the isolated canine mesenteric artery relaxation caused by nicorandil [N-(2-hydroxyethyl)nicotinamide nitrate ester; SG-75] ... Relationship between relaxation and cyclic GMP formation caused by nicorandil in canine mesenteric artery. ... nitrate on smooth muscle cells and on adrenergic transmission in the guinea-pig and porcine mesenteric arteries. J Pharmacol ...
Superior mesenteric artery (SMA) syndrome is an atypical, rare cause of both acute and chronic high intestinal obstruction. ... Laparoscopic duodenojejunostomy for the treatment of superior mesenteric artery (SMA) Syndrome: case series.. Wyten R1, Kelty ...
Learn about diseases of the arteries to the kidneys and intestines, including diagnostic tests, and minimally invasive and ... If renal or mesenteric artery disease is very advanced, or if blockages develop in an artery that is difficult to reach with a ... Renal (kidney) and mesenteric (intestinal) artery disease are conditions that develop when the arteries in the abdomen that ... In mesenteric artery disease, the arteries supplying blood to the intestines are narrowed; people with this condition lose ...
  • In human anatomy , the superior mesenteric artery (SMA) arises from the anterior surface of the abdominal aorta , just inferior to the origin of the celiac trunk , and supplies the intestine from the lower part of the duodenum through two-thirds of the transverse colon , as well as the pancreas . (wikipedia.org)
  • The arteries that supply blood to the intestines run directly from the aorta. (medlineplus.gov)
  • The aorta is the main artery from the heart. (medlineplus.gov)
  • The blockage is removed and the arteries are reconnected to the aorta. (medlineplus.gov)
  • The mesenteric arteries take blood from the aorta and distribute it to a large portion of the gastrointestinal tract. (wikipedia.org)
  • Both the superior and inferior mesenteric arteries arise from the abdominal aorta. (wikipedia.org)
  • Located under this portion of the superior mesenteric artery, between it and the aorta, are the following: left renal vein - travels between the left kidney and the inferior vena cava (can be compressed between the SMA and the abdominal aorta at this location, leading to nutcracker syndrome). (wikipedia.org)
  • Superior mesenteric artery (SMA) syndrome is an uncommon but well recognized clinical entity characterized by compression of the third, or transverse, portion of the duodenum between the aorta and the superior mesenteric artery. (medscape.com)
  • The superior mesenteric artery usually forms an angle of approximately 45° (range, 38-56°) with the abdominal aorta, and the third part of the duodenum crosses caudal to the origin of the superior mesenteric artery, coursing between the superior mesenteric artery and aorta. (medscape.com)
  • Any factor that sharply narrows the aortomesenteric angle to approximately 6-25° can cause entrapment and compression of the third part of the duodenum as it passes between the superior mesenteric artery and aorta, resulting in SMA syndrome. (medscape.com)
  • The mesenteric arteries that deliver blood to your intestines branch off from the aorta, the heart's main artery. (healthline.com)
  • This artery branches off the abdominal aorta and supplies oxygenated blood to the pancreas and the lower parts of the intestine. (healthline.com)
  • The extrinsic compression of the third portion of the duodenum between the superior mesenteric artery and the aorta defines superior mesenteric artery syndrome. (scirp.org)
  • Superior mesenteric artery syndrome is a rare condition that causes a proximal small intestinal obstruction due to contraction of the angle between the superior mesenteric artery and the aorta. (hindawi.com)
  • A diagram of the aorta, including the superior mesenteric artery. (wisegeek.com)
  • Superior mesenteric artery syndrome (SMAS) has been proposed as a rare cause of proximal bowel obstruction resulting from compression of the third portion of the duodenum secondary to narrowing of the space between the aorta and superior mesenteric artery. (isciii.es)
  • The superior mesenteric artery syndrome (SMAS) was first described by Von Rokitansky in 1861 as an obstruction of the third portion of the duodenum between the superior mesenteric artery (SMA) and the aorta. (isciii.es)
  • This syndrome occurs when the fat pad between the superior mesenteric artery and its origin at the aorta is lost, causing a sharp, narrow angle at the aortomesentery junction. (mja.com.au)
  • In human anatomy , the superior mesenteric artery (SMA) arises from the anterior surface of the abdominal aorta , just inferior to the origin of the celiac trunk , and supplies the intestine from the lower part of the duodenum to the left colic flexure and the pancreas . (statemaster.com)
  • The celiac artery, also known as the celiac trunk, is the first major branch of the abdominal aorta and branches from the aorta around the level of the T12 vertebra in humans. (statemaster.com)
  • The mesenteric arteries run directly from the aorta, the main artery from the heart. (wakehealth.edu)
  • Superior mesenteric artery syndrome (SMAS) is an unusual presentation of small bowel obstruction that results from compression of the duodenum between the abdominal aorta, posteriorly, and the superior mesenteric artery, anteriorly. (neurologyadvisor.com)
  • The etiology of SMAS is thought to be the loss of the duodenal fat pad, thus changing the angle between the aorta and the superior mesenteric artery. (neurologyadvisor.com)
  • In summary, any process which changes the angle by which the superior mesenteric artery departs the aorta or results in the loss of the duodenal fat pad would predispose a patient to developing SMAS. (neurologyadvisor.com)
  • The development of SMAS has been correlated to a reduction of the angle of the superior mesenteric artery to the aorta to less than 20 degrees. (neurologyadvisor.com)
  • The aorta was mobilized at the level of the left inferior pulmonary ligament and below the renal arteries. (ctsnet.org)
  • The aorta was cross-clamped distally a few centimeters below the left renal artery. (ctsnet.org)
  • A 22 mm graft with three previously constructed branches corresponding to the celiac, SMA, and right renal arteries was anastomosed to the descending thoracic aorta in a continuous fashion. (ctsnet.org)
  • In a 78-year-old patient I would not prefer thoracophernolaparotomy and cardiopulmonary bypass when there is an easier alternative such as abdominal de-branching (implantation of the both renal arteries, celiac and superior mesenteric arteries with the use of a self made quadrifurcated ringed PTFE graft to the distal infra-renal abdominal aorta) and endovascular stent grafting. (ctsnet.org)
  • Arteries which arise from the abdominal aorta and distribute to most of the intestines. (umassmed.edu)
  • Vasorelaxant activities of Danhong injection and their differential effects on the rat abdominal aorta and mesenteric artery. (sigmaaldrich.com)
  • DHI relaxed NE-induced vasoconstriction probably through inhibition of the intracellular Ca2+ release through the inositol triphosphate receptor system in the abdominal aorta and mesenteric artery, along with blockage of extracellular Ca2+ influx through the receptor-linked Ca2+ channels in the mesenteric artery. (sigmaaldrich.com)
  • Abdominal radiography revealed the dilated stomach ( figure 2 ) and contrast-enhanced CT showed compression at the third part of the duodenum as well as left renal vein ( figures 3 and 4 ), resulted in angulation and reduction in the distance between the aorta and the superior mesenteric artery (SMA), suggesting SMA syndrome. (bmj.com)
  • The distance between the aorta and the superior mesenteric artery (SMA) was indicated (double headed arrow, 4.4 mm). (bmj.com)
  • We recommend that during multiorgan abdominal procurement, when the SMA is procured, it should be divided almost flush to the aorta, therefore preserving the aortic patch to be procured with the renal arteries ( Figs 1c and 1d ). (pubmedcentralcanada.ca)
  • Branch ventrally from the dorsal aorta and anastomose longitudinally along the dorsal wall of the hindgut, forming the caudal part of the supraintestinal artery. (zfin.org)
  • 2 We report a case of a post-traumatic dissection of the abdominal aorta extending into the superior mesenteric artery (SMA) managed successfully by percutaneous endovascular stent placement through a transradial approach. (invasivecardiology.com)
  • In some animals, including humans, branches of these arteries join with the marginal artery of the colon, which means that occlusion of one of the main arteries does not necessarily lead to the death of the part of the gut that it usually supplies. (wikipedia.org)
  • Acute mesenteric artery occlusion is the most common form of acute arterial visceral vessel occlusion. (kup.at)
  • In case of occlusion of the central part of superior mesenteric artery embolectomy in combination with resection of the affected intestine is indicated. (kup.at)
  • BACKGROUND: The outcome and prognostic factors after revascularization of acute thromboembolic occlusion of the superior mesenteric artery (SMA) are poorly documented. (lu.se)
  • These aneurysms usually occur in the presence of chronic stenosis or occlusion of either or both the coeliac artery and superior mesenteric artery (SMA) . (radiopaedia.org)
  • Associated stenosis or occlusion of the coeliac artery and SMA as well as the collateral vessels (e.g. arc of Riolan and marginal artery of Drummond) can also be demonstrated. (radiopaedia.org)
  • Inferior mesenteric artery aneurysm with occlusion of the superior mesenteric artery, coeliac trunk and right renal artery. (radiopaedia.org)
  • We report a combined technique consisting of thrombectomy and thromboaspiration for the treatment of acute embolic occlusion of the superior mesenteric artery (SMA) at the origin. (ovid.com)
  • We performed mechanical thrombectomy using the Solitaire FR revascularization device, a self-expanding and fully retrievable stent-based thrombectomy system for acute intracranial large artery occlusion, combined with manual aspiration through a 6F guiding sheath placed at the SMA origin via a right brachial approach. (ovid.com)
  • The purpose of this study was to characterize the outcome of attempted endovascular intervention in patients with acute embolic or thrombotic superior mesenteric artery (SMA) occlusion. (springermedizin.de)
  • Acosta S, Ögren M, Sternby N-H, Bergqvist D, Björck M (2004) Incidence of acute thromboembolic occlusion of the superior mesenteric artery: a population-based study. (springermedizin.de)
  • Sonesson B, Hinchcliffe R, Dias N, Resch T, Malina M, Ivancev K (2008) Hybrid recanalization of superior mesenteric artery occlusion in acute mesenteric ischemia. (springermedizin.de)
  • Acute thrombo-embolic occlusion of the superior mesenteric artery (SMA) with intestinal infarction is a lethal disease, difficult to diagnose in time, with unknown incidence and cause-specific mortality. (diva-portal.org)
  • There is no accurate non-invasive method available for the diagnosis of acute thromboembolic occlusion of the superior mesenteric artery (SMA). (diva-portal.org)
  • The aim of this study was to measure changes in MBF in the jejunum during stepwise occlusion of the superior mesenteric artery (SMA). (biomedcentral.com)
  • Angiography showed a partially occluded ileiocolic artery in the first patient and a total proximal occlusion of the SMA in the second patient. (openarchives.gr)
  • Spontaneous recanalization of superior mesenteric artery occlusion following angioplasty and stenting of inferior mesenteric artery. (lenus.ie)
  • Regulation of Na+/H+ exchange in mesenteric arteries from spontaneously hypertensive rats. (umassmed.edu)
  • Alterations in Na(+)-H+ exchange in mesenteric arteries from spontaneously hypertensive rats. (umassmed.edu)
  • Arteries from spontaneously hypertensive rats (SHR), stroke-prone spontaneously hypertensive rats (SHRSP) and Wistar-Kyoto controls (WKY) were fixed by immersion and plastic embedded. (lu.se)
  • Inhibition of soluble epoxide hydrolase reduces portal pressure by protecting mesenteric artery myogenic responses in cirrhotic rats. (sigmaaldrich.com)
  • We investigated the effects of soluble epoxide hydrolase (sEH) inhibition on portal pressure and the myogenic response of mesenteric arteries isolated from cirrhotic rats using the sEH inhibitor t-TUCB (trans-4-{4-[3-(4-trifluoromethoxyphenyl)-ureido]cyclohexyloxy}benzoic acid). (sigmaaldrich.com)
  • In comparison with controls, myogenic responses of mesenteric arteries from cirrhotic rats were attenuated at 80-140mmHg, while inhibition of sEH partly reversed the impaired myogenic constriction at 100-140mmHg and exhibited better feedback of vascular smooth muscle to pressure variation. (sigmaaldrich.com)
  • We hypothesized that breaking advanced glycation end product (AGE) cross-links could improve remodeling in mesenteric resistance arteries in Zucker diabetic fatty (ZDF) rats compared with lean Zucker (LZ) rats. (diabetesjournals.org)
  • In LZ rats, HF artery diameter was larger than for NF vessels, but this was not the case in ZDF rats. (diabetesjournals.org)
  • Endothelium-mediated dilation in ZDF rats, which was lower than in LZ rats, was further decreased in HF arteries. (diabetesjournals.org)
  • Nevertheless, we have previously shown that the ability of resistance arteries to adapt their structure and function in response to a chronic rise in blood flow is impaired in Zucker diabetic fatty (ZDF) rats ( 6 ). (diabetesjournals.org)
  • Abstract In this study we examined the structural and functional properties of mesenteric resistance arteries isolated from normotensive and hypertensive vasopressin-deficient rats. (ahajournals.org)
  • First- and second-order mesenteric resistance arteries from hypertensive rats displayed a reduced internal diameter and increased media-to-lumen ratio compared with their normotensive controls. (ahajournals.org)
  • Both first- and second-order mesenteric arteries from hypertensive rats displayed enhanced sensitivity to norepinephrine compared with their normotensive controls. (ahajournals.org)
  • No evidence was found for an impaired endothelium-dependent vasodilatation in arteries from hypertensive rats. (ahajournals.org)
  • Indeed, in hypertensive vasopressin-deficient rats responses to acetylcholine were increased in first-order arteries compared with those from normotensive rats. (ahajournals.org)
  • Responses to papaverine were similar in arteries isolated from either normotensive or hypertensive rats. (ahajournals.org)
  • Third branch mesenteric arteries were isolated from 12 weeks old male Sprague-Dawley (SD) control and (mRen2)27 hypertensive rats and mounted on a wire Multi Myograph (Model 620, DMT) for determination of isometric force. (ahajournals.org)
  • 0.05) arteries from (mRen2)27 rats with no change in sensitivity. (ahajournals.org)
  • Third order mesenteric arteries from male F344 rats, aged 2.5-3 months (young) and 22-26 months (old) were mounted on wire myograph to measure the tension during isometric contraction. (frontiersin.org)
  • Relaxation-concentration response curves produced by cumulative concentrations of three different CCBs in arteries of old rats were shifted to the right with statistically significant IC50s. (frontiersin.org)
  • Parallel to this reduction, the expression of Ca v 1.2 protein was reduced by 57 ± 5% in arteries from old rats compared to those from young rats. (frontiersin.org)
  • In this study, we aimed to assess whether cerebral ischemia/reperfusion could affect vasoconstriction and vasodilatation on mesenteric resistance arteries (MRA) from Wistar Kyoto rats. (aspetjournals.org)
  • In this study, we investigated the mechanism(s) of resveratrol-induced vasorelaxation in resistance mesenteric arteries from male lean and dietary-induced obese rats. (portlandpress.com)
  • Resveratrol (5-35 µ mol/l) induced concentration-dependent relaxation of mesenteric arteries preconstricted with noradrenaline (8 µ mol/l) or KCl (125 mmol/l) from both lean and dietary-obese rats. (portlandpress.com)
  • However, L -NAME (100 and 300 µ mol/l) did not alter the effects of reseveratrol on arteries from dietary-obese rats, giving superimposed concentration-responses curves. (portlandpress.com)
  • Indomethacin was also ineffective in altering resveratrol activity in arteries from both lean and dietary-obese rats. (portlandpress.com)
  • In noradrenaline-precontracted arteries from dietary-obese rats, responses to resveratrol were not attenuated by endothelial denudation, indicating an action independent of the endothelium. (portlandpress.com)
  • This study indicates that: (a) the maximal effects of resveratrol on resistance arteries from lean and dietary-obese rats are not effected by endothelial dysfunction, and (b) the effects of resveratrol in lean animals (where endothelial function is not impaired), but not in dietary-obese rats, are mediated via NO. (portlandpress.com)
  • Here, we tested whether PBR associated with OH affects the α-adrenergic receptor-induced CPI-17 signaling pathway in mesenteric arteries using rats treated by head-down tail-suspension hindlimb unloading (HDU), an experimental OH model. (ebscohost.com)
  • Small mesenteric arteries were isolated from male and female Wistar rats. (clinsci.org)
  • In arteries from female rats, ET-1 increased TG activity, and this effect was prevented by β-oestradiol. (clinsci.org)
  • As anandamide has been implicated in the vasodilated state in advanced cirrhosis, the study investigated whether the mesenteric bed from cirrhotic rats has an altered and selective vasodilator response to anandamide. (bmj.com)
  • We assessed vascular sensitivity to anandamide, mRNA and protein expression of cannabinoid CB1 receptor and TRPV1 receptor, and the topographical distribution of cannabinoid CB1 receptors in resistance mesenteric arteries of cirrhotic and control rats. (bmj.com)
  • Blood flow was increased in vivo in mesenteric resistance arteries after ligating side arteries in 3- and 12-month old male and female rats. (inserm.fr)
  • Arterial diameter and cross sectional area increased in HF, compared to NF arteries, in 3-month old male and female rats. (inserm.fr)
  • Ovariectomy in 12-month old female rats induced a similar pattern with an increased contractility without diameter increase in HF arteries. (inserm.fr)
  • Thus, we found that FMR of resistance arteries remains efficient in 12-month old female rats compared to age-matched male rats. (inserm.fr)
  • In the present study, we investigated the effect of reactive oxygen species (ROS) on the mesenteric artery contractility in CCl 4 -induced cirrhotic rats, and the roles of G protein-coupled receptors (GPCRs) desensitization and RhoA /Rho associated coiled-coil forming protein kinase (ROCK) pathways. (ijbs.com)
  • Pretreatment with apocynin or PEG-catalase in cirrhotic rats, the hydrogen peroxide level in the mesenteric arteriole was significantly decreased, and the dose-response curve of mesenteric arteriole to NE moved to the left with EC 50 decreased. (ijbs.com)
  • The H 2 O 2 decrease in mesenteric artery from rats with cirrhosis resulted in down regulation of the β-arrestin-2 expression and its binding ability with α1 adrenergic receptor, thereby affecting the agonist-induced ROCK activation and improving the contractile response in blood vessels. (ijbs.com)
  • People with acute mesenteric ischemia often do poorly because parts of the intestine may die before surgery can be done. (medlineplus.gov)
  • However, with prompt diagnosis and treatment, acute mesenteric ischemia can be treated successfully. (medlineplus.gov)
  • Due to initially substantially unremarkable abdominal medical reports, acute mesenteric ischemia is frequently diagnosed too late. (kup.at)
  • Aschoff A, Stuber G, Becker BW, Hoffman M, Schmitz B, Schelzig H et al (2008) Evaluation of acute mesenteric ischemia: accuracy of biphasic mesenteric multi-detector CT angiography. (springermedizin.de)
  • Baltazar U, Dunn J, Floresguerra C. Superior mesenteric artery syndrome: an uncommon cause of intestinal obstruction. (medscape.com)
  • The artery branches into several other blood vessels, including the inferior pancreaticoduodenal, the ileocolic, the intestinal, and the right and left colic arteries. (healthline.com)
  • Superior mesenteric artery syndrome determines an acute or chronic intestinal obstruction. (scirp.org)
  • Intestinal arteries - jejunal and ileal - branch and spread throughout the convoluted coils of the small intestine. (wisegeek.com)
  • Obstruction of the superior mesenteric artery, such as a blood clot, can cause intestinal ischemia, which is potentially fatal. (wisegeek.com)
  • The inferior pancreaticoduodenal artery is given off from the superior mesenteric or from its first intestinal branch, opposite the upper border of the inferior part of the duodenum. (statemaster.com)
  • Superior mesenteric artery (SMA) syndrome is an atypical, rare cause of both acute and chronic high intestinal obstruction. (nih.gov)
  • Renal (kidney) and mesenteric (intestinal) artery disease are conditions that develop when the arteries in the abdomen that supply either the kidneys or the intestines become narrowed, or blocked, by an accumulation of a fatty substance called plaque. (nyp.org)
  • After birth, in the first 24 hours of life, and in the transitional period, between the 48th and 72nd hours of life, all infants' intestinal perfusion will be evaluated with NIRS and a doppler of the superior mesenteric artery will be executed. (clinicaltrials.gov)
  • Small Intestinal Injury - Adhesions Blocking Mesenteric Arteries with Bowel Necrosis (Death). (smartimagebase.com)
  • Chronic mesenteric ischemia is a rare intestinal disorder, with a potential evolution toward intestinal infraction. (readbyqxmd.com)
  • Hence, this study was designed to evaluate the effect of aging on the sensitivity of small mesenteric arteries to L-type voltage-gated calcium channel (LTCC) blockers and also to investigate whether there was a concomitant change in calcium current density. (frontiersin.org)
  • In conclusion, our results suggest that aging reduces the response of small mesenteric arteries to the vasodilatory effect of the CCBs and this may be due to, at least in part, reduced current density of LTCC. (frontiersin.org)
  • Previously, we showed that CPI-17, a regulatory protein for myosin phosphatase, mediates α-adrenergic receptor-induced rapid contraction of small mesenteric arteries. (ebscohost.com)
  • Leukotriene D4 relaxes canine renal and superior mesenteric arteries. (ahajournals.org)
  • Isolated dissection of the origin of both celiac and superior mesenteric arteries is a rare vascular pathology with limited management guidelines. (eurekamag.com)
  • The ileal branch of the ileocolic artery is one of five branches that exist in the ileocolic artery. (healthline.com)
  • Lastly, an ileocolic artery, the final terminal branch of the superior mesenteric artery, covers whatever remains, including the appendix . (wisegeek.com)
  • The Right Colic Artery arises from about the middle of the concavity of the superior mesenteric artery, or from a stem common to it and the ileocolic. (statemaster.com)
  • The Ileocolic Artery is the lowest branch arising from the concavity of the superior mesenteric artery. (statemaster.com)
  • What are the branches of the Ileocolic artery? (brainscape.com)
  • If renal or mesenteric artery disease is very advanced, or if blockages develop in an artery that is difficult to reach with a catheter, arterial bypass surgery may be necessary to restore blood flow. (nyp.org)
  • To characterize the influences of leukotriene D4 on regional vascular smooth muscle, effects of leukotriene D4 on vasomotor tone of canine renal and superior mesenteric arterial rings were determined. (ahajournals.org)
  • After tone had been induced with norepinephrine, leukotriene D4, in concentrations of 10(-8) M to 10(-7) M, produced dose-dependent relaxation of renal and superior mesenteric arterial rings. (ahajournals.org)
  • These results demonstrate that leukotriene D4 possesses the capacity to relax canine superior mesenteric and renal arterial rings in an endothelial-dependent manner. (ahajournals.org)
  • Because relaxation of renal and superior mesenteric arterial rings in response to leukotriene D4 was not altered after incubation with indomethacin (10(-5) M), the observed endothelial-dependent relaxation induced by leukotriene D4 did not appear to be related to release of a cyclooxygenase metabolite(s). (ahajournals.org)
  • At seven months of age the ratio was significantly increased in mesenteric arterial branches of SHR and SHRSP and in renal arterial branches of SHRSP. (lu.se)
  • The media to radius ratio was markedly increased in the renal and superior mesenteric arterial trunks of adult SHR (P less than 0.001 in both) and SHRSP (P less than 0.001 and P less than 0.01). (lu.se)
  • Typical features of localized arterial dissection with resultant aneurysmal dilatation of the superior mesenteric artery. (radiopaedia.org)
  • Arteries, exposed to high (HF) or normal (NF) blood flow after alternate arterial ligation in vivo, were collected after 2 weeks. (diabetesjournals.org)
  • First- and second-order mesenteric resistance arteries were set up in a pressure myograph and pressurized to the mean arterial pressure of the rat from which they had been isolated. (ahajournals.org)
  • Rapid constriction of splanchnic resistance arteries in response to a sudden increase in sympathetic tone contributes to the recovery of orthostatic arterial pressure upon standing. (ebscohost.com)
  • The entire arterial blood supply to the liver, therefore, was derived from the superior mesenteric artery. (springermedizin.de)
  • the third part of the duodenum , a segment of the small intestines (can be compressed by the SMA at this location, leading to superior mesenteric artery syndrome ). (wikipedia.org)
  • and/or the third (horizontal) part of the duodenum , leading to superior mesenteric artery syndrome . (wikipedia.org)
  • [ 1 ] Superior mesenteric artery syndrome was first described in 1861 by Von Rokitansky, who proposed that its cause was obstruction of the third part of the duodenum as a result of arteriomesenteric compression. (medscape.com)
  • Alternatively, other causes implicated in superior mesenteric artery syndrome include high insertion of the duodenum at the ligament of Treitz, a low origin of the superior mesenteric artery, and compression of the duodenum due to peritoneal adhesions. (medscape.com)
  • This is not the same as superior mesenteric artery syndrome, which involves the artery compressing the duodenum. (healthline.com)
  • An inferior pancreaticoduodenal artery supplies blood to the pancreas and most of the duodenum, which connects the stomach to the small intestine. (wisegeek.com)
  • Superior mesenteric artery syndrome, which is potentially fatal, depending on the degree of obstruction, arises when the digestive tract is disrupted by a compressed duodenum. (wisegeek.com)
  • Superior mesenteric artery syndrome occurs when the duodenum is compressed by a large artery in the abdomen. (wisegeek.com)
  • Exhaustive preoperative workup identified the source to be duodenal obstruction secondary to external compression of the third portion of the duodenum by the superior mesenteric artery, hence superior mesenteric artery syndrome. (sages.org)
  • It shows a complete duodenal obstruction due to exterior compression of the third part of the duodenum by the superior mesenteric artery. (elsevier.es)
  • DUODENAL OBSTRUCTION by the superior mesenteric artery (MESENTERIC ARTERY, SUPERIOR) which travels in the root of the MESENTERY and crosses over the DUODENUM. (curehunter.com)
  • The superior mesenteric artery takes off from the duodenum at an angle of 45 degrees to 60 degrees in normal individuals. (luriechildrens.org)
  • A mesh tube called a stent is inserted into the narrowed artery to hold it open. (healthline.com)
  • Spontaneous dissection of the superior mesenteric artery in four cases treated with anticoagulation therapy," Internal Medicine , vol. 43, no. 6, pp. 473-478, 2004. (hindawi.com)
  • Spontaneous isolated dissection of the superior mesenteric artery (SIDSMA) is a rare vascular disease. (minervamedica.it)
  • Saisho H, Okazaki T, Shimoishi K, Hori H, Tayama K. Two cases of spontaneous isolated dissection of the superior mesenteric artery treated with conservative therapy. (minervamedica.it)
  • Several major blood vessels branch from it, and just 0.4 inches (1 cm) below the celiac trunk, which services the stomach, liver and spleen, is the junction of the superior mesenteric artery. (wisegeek.com)
  • Bianchi C., Ballard J.L. (2006) Transaortic Celiac and Superior Mesenteric Artery Endarterectomy. (springer.com)
  • The celiac, superior mesenteric, and right and left renal arteries were divided and cannulated. (ctsnet.org)
  • Dear Murat, That is another alternative for the case like that, however abdominal debranching is major undertaking and still requires reimplantation of celiac, SMA and renal arteries. (ctsnet.org)
  • 6. Tsukioka K, Nobara H, Nishimura K. A case of inferior mesenteric artery aneurysm with an occlusive disease in superior mesenteric artery and the celiac artery. (radiopaedia.org)
  • In addition, an obstructive disease of the superior mesenteric artery and celiac axis was observed. (celiac.com)
  • 2201F08circulation2post - iliac common iliac Celiac artery. (coursehero.com)
  • iliac common iliac Celiac artery Superior mesenteric artery Inferior mesenteric artery Gonadal (testicular, ovarian) renal renal hepatic veins deep femoral a fibular a radial v ulnar v fibular v post. (coursehero.com)
  • The gastroduodenal artery and the right inferior phrenic artery took origin from the celiac trunk. (springermedizin.de)
  • The celiac trunk gave off three branches: the splenic, left gastric, and gastroduodenal arteries. (springermedizin.de)
  • This case report details the clinical course of a 57-year-male who presented with a 2-week history of epigastric discomfort with back pain and was found to have focal celiac artery dissection with aneurysmal dilation of 1.2 cm. (eurekamag.com)
  • There are 71 cases of SMA and 12 cases of celiac artery dissection in the literature. (eurekamag.com)
  • This report outlines this rare presentation of isolated, proximal sequential celiac artery and SMA dissection. (eurekamag.com)
  • 3D-rendered computed tomography of abdominal aortic branches, showing exit of superior mesenteric artery between the kidneys. (wikipedia.org)
  • Mesenteric artery disease is a type of peripheral vascular disease, which also includes peripheral artery disease , carotid artery disease , renal artery disease , aortic disease, venous problems , and some other conditions, such as vasculitis. (wakehealth.edu)
  • The results showed that DHI significantly inhibited rat-hindquarters and rabbit-ear vasoconstriction elicited by norepinephrine (NE) perfusion and markedly relaxed KCl-contracted and NE-contracted rat abdominal aortic and mesenteric artery rings. (sigmaaldrich.com)
  • Abdominal ultrasound demonstrated a reduced superior mesenteric-aortic angle and distance. (kuleuven.be)
  • Acute aortic dissection extending into the superior mesenteric artery (SMA) following a blunt trauma is an extremely rare complication. (invasivecardiology.com)
  • We report our early experience with a novel approach using a tissue expander (TE) to lengthen the normal native arteries in children with MAS, allowing primary aortic repair without the need for prosthetic graft material. (readbyqxmd.com)
  • He had previously experienced thoracic and abdominal aortic dissections, which were treated with thoracic and abdominal aortic grafts and superior mesenteric artery revascularization. (readbyqxmd.com)
  • Atherosclerosis affects up to 35 percent of Americans, and can cause narrowing (also called stenosis) of any of the arteries throughout the body. (nyp.org)
  • Although superior mesenteric artery stenosis is a relatively common situation, it is rarely symptomatic due to the fact that in a significant number of cases an adequate collateral circulation exists. (spandidos-publications.com)
  • The 47‑year‑old patient was investigated for chronic postprandial pain and was diagnosed with superior mesenteric artery stenosis. (spandidos-publications.com)
  • Although superior mesenteric artery stenosis represents a relatively frequent pathological condition with increasing prevalence with age, it rarely becomes symptomatic due to the fact that most often the presence of an adequate collateral circulation will prevent the apparition of chronic mesenteric ischemia ( 1-3 ). (spandidos-publications.com)
  • Renal artery stenosis (RAS) of the anastomosis may lead to deterioration of graft function, hypertension and graft failure. (pubmedcentralcanada.ca)
  • Usefulness of angioplasty in a patient with biopsy-proven giant cell arteritis and severe stenosis of the superior mesenteric artery. (jrheum.org)
  • We present a case of reperfusion hemorrhage complicating endovascular repair of superior mesenteric artery stenosis. (lenus.ie)
  • Although a recognized complication following repair of carotid stenosis, hemorrhage has not previously been reported following mesenteric endovascular reperfusion. (lenus.ie)
  • Superior mesenteric artery stenosis treated with percutaneous transluminal angioplasty and stent placement. (lenus.ie)
  • Superior mesenteric artery stent fracture producing stenosis and recurrent chronic mesenteric ischemia: case report. (lenus.ie)
  • Chronic mesenteric ischemia due to superior mesenteric artery stenosis. (lenus.ie)
  • Tissue death from lack of blood flow (infarction) in the intestines is the most serious complication of mesenteric artery ischemia. (medlineplus.gov)
  • The loss of retroperitoneal fat has been postulated as a major factor in the cause of the uncommon complication of superior mesenteric artery syndrome. (biomedsearch.com)
  • Laparoscopic duodenojejunostomy for the treatment of superior mesenteric artery (SMA) Syndrome: case series. (nih.gov)
  • Surgical treatment of superior mesenteric artery syndrome]. (semanticscholar.org)
  • article{Yang1991SurgicalTO, title={[Surgical treatment of superior mesenteric artery syndrome]. (semanticscholar.org)
  • [ 2 ] Approximately 0.013-0.78% of barium upper GI studies evaluating for superior mesenteric artery syndrome support the diagnosis. (medscape.com)
  • indeed, some investigators have suggested that superior mesenteric artery syndrome is overdiagnosed because it is confused with other causes of megaduodenum. (medscape.com)
  • In addition, the aortomesenteric distance in superior mesenteric artery syndrome is decreased to 2-8 mm (normal is 10-20 mm). (medscape.com)
  • In a review of the literature, approximately 0.013-0.78% of the findings from upper GI tract barium studies support a diagnosis of superior mesenteric artery syndrome. (medscape.com)
  • Gerasimidis T, George F. Superior Mesenteric Artery Syndrome. (medscape.com)
  • Clinical and nutritional outcomes in children with idiopathic superior mesenteric artery syndrome. (medscape.com)
  • Merrett ND, Wilson RB, Cosman P, Biankin AV. Superior mesenteric artery syndrome: diagnosis and treatment strategies. (medscape.com)
  • Kyslan K, Barla J, Kyslan K, Stanislayova M. [Superior mesenteric artery (SMAS/AMS) syndrome and its management]. (medscape.com)
  • There are two known pathological conditions associated with the superior mesenteric artery: nutcracker syndrome and superior mesenteric artery syndrome. (healthline.com)
  • Nutcracker syndrome occurs when the artery compresses the renal vein. (healthline.com)
  • Superior Mesenteric Artery Syndrome Presenting with Pneumoperiton. (ingentaconnect.com)
  • We report the first case of superior mesenteric artery syndrome in Chad and discuss the etiopathogenic aspects, the diagnostic and therapeutic means. (scirp.org)
  • Superior mesenteric artery syndrome is a rare digestive system disorder. (iffgd.org)
  • Scoliosis surgery is one of the 15 reasons for superior mesenteric artery syndrome, which can present with acute or chronic manifestations. (hindawi.com)
  • In this paper, we describe a patient who developed superior mesenteric artery syndrome after scoliosis surgery and was treated with duodenojejunostomy due to failure and complications of conservative treatment. (hindawi.com)
  • This video illustrates the role of laparoscopy for Superior Mesenteric Artery Syndrome. (sages.org)
  • Laparoscopy is a safe, effective, and readily available alternative for patients with Superior Mesenteric Artery Syndrome, that fails to resolve with alternative approaches. (sages.org)
  • She was diagnosed with superior mesenteric artery syndrome and treated with laparoscopic duodeno-jejunostomy with resolution of symptoms. (sages.org)
  • Superior mesenteric artery syndrome in a burn patient. (biomedsearch.com)
  • This case study describes the nutrition management of a burn patient who developed superior mesenteric artery syndrome. (biomedsearch.com)
  • Superior mesenteric artery syndrome with hepatic portal venous gas was diagnosed. (mja.com.au)
  • 2. Ylinen P, Kinnunen J, Hockerstedt K. Superior mesenteric artery syndrome. (mja.com.au)
  • One possible misdiagnosis is the failure to correctly diagnose Mesenteric artery syndrome leading to a person remaining with undiagnosed Mesenteric artery syndrome. (rightdiagnosis.com)
  • Diagnosis: Superior mesenteric artery syndrome or Wilkie's syndrome. (elsevier.es)
  • Are you sure your patient has Superior Mesenteric Artery Syndrome? (neurologyadvisor.com)
  • superior mesenteric artery syndrome is a topic covered in the Taber's Medical Dictionary . (tabers.com)
  • Taber's Online , www.tabers.com/tabersonline/view/Tabers-Dictionary/729140/all/superior_mesenteric_artery_syndrome. (tabers.com)
  • Superior mesenteric artery syndrome may cause acute abdominal pain. (bmj.com)
  • Pediatric orthopedists are familiar with this entity, as the association between superior mesenteric artery syndrome and spinal fusion or body casting has been well established. (luriechildrens.org)
  • Only 2 cases of superior mesenteric artery syndrome in patients with sagittal plane spinal deformity have been described in the literature. (luriechildrens.org)
  • In patients with concomitant superior mesenteric artery syndrome and spinal deformity, correction of the deformity may help alleviate the obstruction and result in faster recovery. (luriechildrens.org)
  • Fourty-two patients with superior mesenteric artery syndrome were treated surgically. (semanticscholar.org)
  • Clinical and Radiologic Considerations for Idiopathic Superior Mesenteric Artery Syndrome. (readbyqxmd.com)
  • Superior mesenteric artery (SMA) syndrome often occurs in the setting of rapid weight loss and scoliosis corrective spinal surgery. (readbyqxmd.com)
  • Tests for mesenteric artery disease help confirm a diagnosis or rule it out. (wakehealth.edu)
  • Sonographic diagnosis of inferior mesenteric artery aneurysm and marginal artery of Drummond. (radiopaedia.org)
  • Rupture of a superior mesenteric artery aneurysm]. (biomedsearch.com)
  • CT-scan showed a peripherally located ruptured aneurysm of a branch of the superior mesenteric artery. (biomedsearch.com)
  • Atherosclerosis can also cause an aneurysm-a weakened, bulging part of the artery that can rupture and cause internal bleeding. (nm.org)
  • A case of atherosclerotic inferior mesenteric artery aneurysm secondary to high flow state. (radiopaedia.org)
  • Inferior mesenteric artery aneurysm: case report and literature review. (radiopaedia.org)
  • Superior mesenteric artery aneurysm i. (ugent.be)
  • This is a presentation of a 33 year old female who underwent laparoscopic Roux-en-Y gastric bypass in 2006 who developed recurrent pancreatitis and abdominal. (sages.org)
  • Over the period of November 2015 to November 2016, 18 patients underwent laparoscopic pancreaticoduodenectomy with major venous resection and reconstruction using the anterior superior mesenteric artery (SMA)-first approach at our institution. (unboundmedicine.com)
  • Short-term and long-term results of a randomized study comparing high tie and low tie inferior mesenteric artery ligation in laparoscopic rectal an. (nih.gov)
  • Short-term and long-term results of a randomized study comparing high tie and low tie inferior mesenteric artery ligation in laparoscopic rectal anterior resection: subanalysis of the HTLT (High tie vs. low tie) study. (nih.gov)
  • This artery is completed by branches of the left colic which is a branch of the inferior mesenteric artery . (wikipedia.org)
  • Anatomy figure: 39:02-01 at Human Anatomy Online, SUNY Downstate Medical Center - "Branches of the inferior mesenteric artery. (wikipedia.org)
  • Superior mesenteric artery Inferior mesenteric artery Gray, Henry (1918). (wikipedia.org)
  • In an attempt to determine whether "high ligation" of the inferior mesenteric artery during surgery for cancer of the rectum and rectosigmoid confers any significant 5-year survival advantage over "low ligation," the outcome of 1370 patients was reviewed. (nih.gov)
  • There were 784 patients in whom the inferior mesenteric artery was ligated below the origin of the left colic artery (low ligation) and 586 in whom it was ligated above this level (high ligation). (nih.gov)
  • In conclusion, high ligation of the inferior mesenteric artery has not been found to improve 5-year survival in patients with cancer of the rectum or rectosigmoid. (nih.gov)
  • Inferior mesenteric artery aneurysms are among the rarest of all visceral artery aneurysms . (radiopaedia.org)
  • In rectal anterior resection, a clear consensus regarding the optimal level of inferior mesenteric artery (IMA) ligation does not exist because of a lack of randomized trials. (nih.gov)
  • left colic inferior mesenteric B. left colic superior mesenteric C. (coursehero.com)
  • Each of these arteries travel through the mesentery, within which they branch several times before reaching the gut. (wikipedia.org)
  • The superior mesenteric artery does, however, further branch. (wisegeek.com)
  • The middle colic artery is a branch of the superior mesenteric artery that mostly supplies the transverse colon. (statemaster.com)
  • Right branch of middle colic artery. (brainscape.com)
  • The descending colon is supplied by the artery, a branch of the _ artery. (coursehero.com)
  • Narrowing of the arteries occurs when fat, cholesterol, and other substances build up in the walls of arteries (atherosclerosis). (medlineplus.gov)
  • The fatty build-up leading to atherosclerosis is not an issue with this artery as it is with other vessels in the body. (healthline.com)
  • As plaque builds up inside the artery walls, the arteries can become hardened and narrowed (a process called atherosclerosis). (nyp.org)
  • As atherosclerosis affects the whole body, people with renal or mesenteric artery narrowing often have other cardiovascular conditions such as carotid artery disease and heart disease. (nyp.org)
  • Risk factors for renal and mesenteric artery disease include smoking - the number one risk factor for all cardiovascular diseases - a family history of atherosclerosis, high blood pressure, diabetes, high cholesterol, advanced age, obesity, and a sedentary lifestyle. (nyp.org)
  • Chronic (long-term) - Mesenteric artery disease that results from fatty deposits, called plaque, building up in the arteries, causing them to become narrow and blocked (a process called atherosclerosis). (wakehealth.edu)
  • The buildup of plaque in the arteries (atherosclerosis) is common in people who are smokers, have high blood pressure or high cholesterol . (wakehealth.edu)
  • Chronic mesenteric artery disease may be caused by atherosclerosis (hardening of the arteries). (nm.org)
  • People with hardening of the arteries that supply the intestines often have the same problems in blood vessels that supply the heart, brain, kidneys, or legs. (medlineplus.gov)
  • The term mesenteric artery is also used to describe smaller branches of these vessels which, particularly in smaller animals, provide a significant source of vascular resistance. (wikipedia.org)
  • by constricting the smaller mesenteric vessels, the resistance of blood flow to the gut increases, and hence blood flows more readily to other organs. (wikipedia.org)
  • The posterior scrotal artery is made up of a group of blood vessels found near the external genitalia of the male human body. (healthline.com)
  • To perform these tests, doctors place a tiny, soft plastic tube called a catheter into the artery or vein, usually in the groin, and inject a dye that makes the blood vessels clearly visible on an x-ray image. (nyp.org)
  • The mesenteric arteries are blood vessels that carry blood to the intestines. (nm.org)
  • 4 5 6 7 8 9 10 11 Data from many studies have indicated that the internal diameter of arteries from hypertensive animals is smaller than that of equivalent vessels from normotensive controls. (ahajournals.org)
  • Mesenteric vessels of cirrhotic animals displayed greater sensitivity to anandamide than control vessels. (bmj.com)
  • Surgery can treat chronic mesenteric artery ischemia, if needed. (healthline.com)
  • Most people with chronic mesenteric artery ischemia recover well with treatment and lifestyle changes. (healthline.com)
  • However, there was no evidence for an increased media content, indicating that the reduced internal diameter of hypertensive arteries was consequent to either remodeling of similar amounts of wall material or a reduced artery distensibility but not vascular growth. (ahajournals.org)
  • 2 3 In particular, isometric recording systems have been used extensively for examination of the properties of arteries isolated from hypertensive animals compared with their normotensive controls. (ahajournals.org)
  • In addition, DHI completely relaxed KCl-induced contraction in both of the arteries, suggesting that inhibition of Ca2+ influx through voltage-gated Ca2+ channels is involved in the vasorelaxant effect of DHI. (sigmaaldrich.com)
  • The ionic basis of the UTP induced contraction was studied by measuring the effect of UTP on various ionic currents measured in enzymatically isolated mesenteric artery smooth muscle cells using the whole-cell patch-clamp technique. (bl.uk)
  • The HDU treatment resulted in 68% reduction in contraction in parallel with 83% reduction in CPI-17 phosphorylation in denuded mesenteric arteries 10 s after α-agonist stimulation. (ebscohost.com)
  • Endothelin-1 causes long-lasting contraction via endothelin type A receptor (ETAR) in isolated rat mesenteric arteries (RMA) that cannot be readily terminated by removing the agonist, or by adding the ETAR antagonist BQ123 or the NO donor sodium nitroprusside. (eur.nl)
  • The mesenteric artery contraction to norepinephrine (NE) was determined by vessel perfusion system following treatments with apocynin, tempol or PEG-catalase. (ijbs.com)
  • This allows the superior mesenteric artery to rest directly on the small intestine, resulting in obstruction. (neurologyadvisor.com)
  • Mesenteric artery ischemia occurs when there is a narrowing or blockage of one or more of the three major arteries that supply the small and large intestines. (medlineplus.gov)
  • This can show the location of the blockage in the artery. (medlineplus.gov)
  • A stent may be used as an alternative to surgery to enlarge the blockage in the artery or to deliver medicine directly to the affected area. (medlineplus.gov)
  • A complete blockage may also occur when a blood clot obstructs all blood flow through the artery, causing tissue death of that segment of intestine (infarction). (medlineplus.gov)
  • In cases of total blockage, sometimes the blocked artery is bypassed altogether. (healthline.com)
  • In case of a nonocclusive blockage of the superior mesenteric artery, an intraaterial infusion of vasoactive substances will be administered during the early stage. (kup.at)
  • When the catheter reaches the blockage, the balloon is inflated to widen the narrowed artery. (nyp.org)
  • A stent is a small tube that holds open the artery at the site of the blockage. (nyp.org)
  • Ishigami K, Zhang Y, Rayhill S et al (2004) Does variant hepatic artery anatomy in a liver a transplant recipient increase the risk of hepatic artery complications after transplantation? (springermedizin.de)
  • therefore, it was crucial to identify the primary feeding artery and vascular anatomy before and during surgery. (readbyqxmd.com)
  • If you or someone you love is diagnosed with mesenteric artery disease, the Northwestern Medicine Center for Vascular Disease offers leading-edge diagnostic testing as well as advanced medical and surgical treatment options. (nm.org)
  • We therefore characterised the vasodilator mechanisms of a major constituent of fish oils, DHA in vascular relaxation of rat mesenteric artery. (bmj.com)
  • ALT-711 also improved endothelium nitric oxide-dependent relaxation in mesenteric resistance arteries. (diabetesjournals.org)
  • For this purpose, resistance arteries can adapt to chronic increases in blood flow, leading to diameter enlargement (outward remodeling) and higher endothelium nitric oxide (NO)-dependent relaxation ( 7 - 9 ). (diabetesjournals.org)
  • Endothelial NO-synthase expression and endothelium-mediated relaxation were higher in HF than in NF arteries in all groups. (inserm.fr)
  • What is the path of the left colic artery? (brainscape.com)
  • What are the branches of the left colic artery? (brainscape.com)
  • We conducted a randomized trial to determine if the IMA should be tied at the origin (high tie, HT) or distal to the left colic artery (low tie, LT) (HTLT study). (nih.gov)
  • With mesenteric artery disease, patients can experience weight loss and severe abdominal pain when they eat. (nyp.org)
  • Spontaneous superior mesenteric artery (SMA) dissection: an unusual cause of abdominal pain. (radiopaedia.org)
  • Two weeks later, recurrent abdominal pain prompted a repeat computed tomographic scan that revealed sequential superior mesenteric artery (SMA) dissection. (eurekamag.com)
  • A left retroperitoneal approach via the 8th intercostal space was performed and the left common femoral artery and vein were cannulated. (ctsnet.org)
  • This often leads to a deficient CP on the anterosuperior aspect of the renal arteries and at worst, damage to the main renal artery (Figs 1a and 1b). (pubmedcentralcanada.ca)
  • Histamine, norepinephrine and KCl each evoke contractile responses in isolated guinea-pig mesenteric artery. (aspetjournals.org)
  • We have investigated effects of altered extracellular sodium, intracellular sodium concentration, and membrane potential on the contractile responses of rat isolated mesenteric small arteries (internal diameter ca. 200 microns), when mounted as ring preparations on an isometric myograph. (ahajournals.org)
  • The research presented in this thesis describes the measurement of isometric contractile responses of rat mesenteric arteries to UTP and of the electrophysiological measurements of ionic currents of smooth muscle cells isolated from these arteries. (bl.uk)
  • Mice are increasingly used in vascular research for studying perturbations and responses to vasoactive agents in small artery preparations. (ku.dk)
  • Second, by surveying the literature, we aimed to evaluate the overall translatability of observed pharmacological vasomotor responses of mouse MRA to those obtained in rat MRA as well as corresponding and different arteries in terms of vessel size and species origin. (ku.dk)
  • Furthermore, we found that the observed concentration-dependent vasomotor responses of mouse MRA to noradrenaline, phenylephrine, angiotensin II, sarafotoxin 6c, 5-hydroxytryptamine, carbachol, sodium nitroprusside, and retigabine were generally similar to those described in rat MRA as well as arteries of different sizes and species origin. (ku.dk)
  • It was hypothesized that hyperbaric oxygen treatment alters vascular reactivity in mesenteric arteries due to enhanced production of ATP resulting in significantly larger responses to vasoactive stimuli. (gvsu.edu)
  • The outlook for chronic mesenteric ischemia is good after a successful surgery. (medlineplus.gov)
  • Natural history of spontaneous isolated superior mesenteric artery dissection derived from follow-up after conservative treatment," Journal of Vascular Surgery , vol. 54, no. 6, pp. 1727-1733, 2011. (hindawi.com)
  • Current strategy for the treatment of symptomatic spontaneous isolated dissection of superior mesenteric artery," Journal of Vascular Surgery , vol. 54, no. 2, pp. 461-466, 2011. (hindawi.com)
  • Surgery can create scar tissue that narrows the arteries. (healthline.com)
  • In more severe cases, we may recommend surgery to open your arteries and restore blood flow. (wakehealth.edu)
  • Mesenteric artery ischemia is a condition that restricts blood flow to your intestines. (healthline.com)
  • Blood clots can block the mesenteric arteries and reduce blood flow to the digestive tract. (healthline.com)
  • In renal artery disease, the narrowed arteries reduce blood flow to the kidneys, causing progressive kidney failure or difficult-to-control high blood pressure in a significant number of patients. (nyp.org)
  • To surgically correct the decreased blood flow through the artery, doctors place a bypass graft made of synthetic material or a natural vein taken from another part of the body. (nyp.org)
  • Mesenteric artery disease occurs when blood flow to one of the arteries to the intestines is blocked. (nm.org)
  • Plaque made of fat, cholesterol and calcium builds up in an artery over time, reducing blood flow to the intestines. (nm.org)
  • Type 2 diabetes is associated with an increase in ROS production ( 13 ) that might impair the ability of resistance arteries to adapt their structure and function in response to chronic increases in blood flow attributed to decreased NO bioavailability ( 14 ). (diabetesjournals.org)
  • Learn the causes and risk factors for mesenteric ischemia, which is decreased or blocked blood flow to the intestines. (nm.org)
  • In resistance arteries a chronic increase in blood flow induces hypertrophic outward remodeling. (inserm.fr)