SARS Virus: A species of CORONAVIRUS causing atypical respiratory disease (SEVERE ACUTE RESPIRATORY SYNDROME) in humans. The organism is believed to have first emerged in Guangdong Province, China, in 2002. The natural host is the Chinese horseshoe bat, RHINOLOPHUS sinicus.Severe Acute Respiratory Syndrome: A viral disorder characterized by high FEVER, dry COUGH, shortness of breath (DYSPNEA) or breathing difficulties, and atypical PNEUMONIA. A virus in the genus CORONAVIRUS is the suspected agent.Spike Glycoprotein, Coronavirus: A class I viral fusion protein that forms the characteristic spikes, or peplomers, found on the viral surface that mediate virus attachment, fusion, and entry into the host cell. During virus maturation, it is cleaved into two subunits: S1, which binds to receptors in the host cell, and S2, which mediates membrane fusion.Nucleocapsid Proteins: Viral proteins found in either the NUCLEOCAPSID or the viral core (VIRAL CORE PROTEINS).RNA Viruses: Viruses whose genetic material is RNA.Vaccinia virus: The type species of ORTHOPOXVIRUS, related to COWPOX VIRUS, but whose true origin is unknown. It has been used as a live vaccine against SMALLPOX. It is also used as a vector for inserting foreign DNA into animals. Rabbitpox virus is a subspecies of VACCINIA VIRUS.Receptors, Virus: Specific molecular components of the cell capable of recognizing and interacting with a virus, and which, after binding it, are capable of generating some signal that initiates the chain of events leading to the biological response.Virus Replication: The process of intracellular viral multiplication, consisting of the synthesis of PROTEINS; NUCLEIC ACIDS; and sometimes LIPIDS, and their assembly into a new infectious particle.Virus Cultivation: Process of growing viruses in live animals, plants, or cultured cells.Virus Shedding: The expelling of virus particles from the body. Important routes include the respiratory tract, genital tract, and intestinal tract. Virus shedding is an important means of vertical transmission (INFECTIOUS DISEASE TRANSMISSION, VERTICAL).Virus Diseases: A general term for diseases produced by viruses.Simian virus 40: A species of POLYOMAVIRUS originally isolated from Rhesus monkey kidney tissue. It produces malignancy in human and newborn hamster kidney cell cultures.Virus Assembly: The assembly of VIRAL STRUCTURAL PROTEINS and nucleic acid (VIRAL DNA or VIRAL RNA) to form a VIRUS PARTICLE.Plant Viruses: Viruses parasitic on plants higher than bacteria.DNA Viruses: Viruses whose nucleic acid is DNA.Defective Viruses: Viruses which lack a complete genome so that they cannot completely replicate or cannot form a protein coat. Some are host-dependent defectives, meaning they can replicate only in cell systems which provide the particular genetic function which they lack. Others, called SATELLITE VIRUSES, are able to replicate only when their genetic defect is complemented by a helper virus.Sindbis Virus: The type species of ALPHAVIRUS normally transmitted to birds by CULEX mosquitoes in Egypt, South Africa, India, Malaya, the Philippines, and Australia. It may be associated with fever in humans. Serotypes (differing by less than 17% in nucleotide sequence) include Babanki, Kyzylagach, and Ockelbo viruses.Measles virus: The type species of MORBILLIVIRUS and the cause of the highly infectious human disease MEASLES, which affects mostly children.Influenza A Virus, H1N1 Subtype: A subtype of INFLUENZA A VIRUS with the surface proteins hemagglutinin 1 and neuraminidase 1. The H1N1 subtype was responsible for the Spanish flu pandemic of 1918.Coronavirus: A genus of the family CORONAVIRIDAE which causes respiratory or gastrointestinal disease in a variety of vertebrates.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Rabies virus: The type species of LYSSAVIRUS causing rabies in humans and other animals. Transmission is mostly by animal bites through saliva. The virus is neurotropic multiplying in neurons and myotubes of vertebrates.Influenza A Virus, H5N1 Subtype: A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 5 and neuraminidase 1. The H5N1 subtype, frequently referred to as the bird flu virus, is endemic in wild birds and very contagious among both domestic (POULTRY) and wild birds. It does not usually infect humans, but some cases have been reported.Influenza A Virus, H3N2 Subtype: A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 3 and neuraminidase 2. The H3N2 subtype was responsible for the Hong Kong flu pandemic of 1968.Hepatitis B virus: The type species of the genus ORTHOHEPADNAVIRUS which causes human HEPATITIS B and is also apparently a causal agent in human HEPATOCELLULAR CARCINOMA. The Dane particle is an intact hepatitis virion, named after its discoverer. Non-infectious spherical and tubular particles are also seen in the serum.West Nile virus: A species of FLAVIVIRUS, one of the Japanese encephalitis virus group (ENCEPHALITIS VIRUSES, JAPANESE). It can infect birds and mammals. In humans, it is seen most frequently in Africa, Asia, and Europe presenting as a silent infection or undifferentiated fever (WEST NILE FEVER). The virus appeared in North America for the first time in 1999. It is transmitted mainly by CULEX spp mosquitoes which feed primarily on birds, but it can also be carried by the Asian Tiger mosquito, AEDES albopictus, which feeds mainly on mammals.RNA, Viral: Ribonucleic acid that makes up the genetic material of viruses.Vero Cells: A CELL LINE derived from the kidney of the African green (vervet) monkey, (CERCOPITHECUS AETHIOPS) used primarily in virus replication studies and plaque assays.Respiratory Syncytial Viruses: A group of viruses in the PNEUMOVIRUS genus causing respiratory infections in various mammals. Humans and cattle are most affected but infections in goats and sheep have also been reported.Disease Outbreaks: Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS.Antigens, Viral: Substances elaborated by viruses that have antigenic activity.Viral Proteins: Proteins found in any species of virus.Cercopithecus aethiops: A species of CERCOPITHECUS containing three subspecies: C. tantalus, C. pygerythrus, and C. sabeus. They are found in the forests and savannah of Africa. The African green monkey (C. pygerythrus) is the natural host of SIMIAN IMMUNODEFICIENCY VIRUS and is used in AIDS research.Genes, Viral: The functional hereditary units of VIRUSES.Virus Activation: The mechanism by which latent viruses, such as genetically transmitted tumor viruses (PROVIRUSES) or PROPHAGES of lysogenic bacteria, are induced to replicate and then released as infectious viruses. It may be effected by various endogenous and exogenous stimuli, including B-cell LIPOPOLYSACCHARIDES, glucocorticoid hormones, halogenated pyrimidines, IONIZING RADIATION, ultraviolet light, and superinfecting viruses.Vesicular stomatitis Indiana virus: The type species of VESICULOVIRUS causing a disease symptomatically similar to FOOT-AND-MOUTH DISEASE in cattle, horses, and pigs. It may be transmitted to other species including humans, where it causes influenza-like symptoms.Virus Latency: The ability of a pathogenic virus to lie dormant within a cell (latent infection). In eukaryotes, subsequent activation and viral replication is thought to be caused by extracellular stimulation of cellular transcription factors. Latency in bacteriophage is maintained by the expression of virally encoded repressors.Hemagglutinin Glycoproteins, Influenza Virus: Membrane glycoproteins from influenza viruses which are involved in hemagglutination, virus attachment, and envelope fusion. Fourteen distinct subtypes of HA glycoproteins and nine of NA glycoproteins have been identified from INFLUENZA A VIRUS; no subtypes have been identified for Influenza B or Influenza C viruses.Saudi ArabiaEgypt: A country in northern Africa, bordering the Mediterranean Sea, between Libya and the Gaza Strip, and the Red Sea north of Sudan, and includes the Asian Sinai Peninsula Its capital is Cairo.Middle East: The region of southwest Asia and northeastern Africa usually considered as extending from Libya on the west to Afghanistan on the east. (From Webster's New Geographical Dictionary, 1988)Arabia: The great peninsula of southwest Asia comprising most of the present countries of the Middle East. It has been known since the first millennium B.C. In early times it was divided into Arabia Petraea, the northwest part, the only part ever conquered, becoming a Roman province; Arabia Deserta, the northern part between Syria and Mesopotamia; and Arabia Felix, the main part of the peninsula but by some geographers restricted to modern Yemen. (From Webster's New Geographical Dictionary, 1988, p63)Library Services: Services offered to the library user. They include reference and circulation.Libraries, MedicalHospitals, Voluntary: Private, not-for-profit hospitals that are autonomous, self-established, and self-supported.Patient Care Team: Care of patients by a multidisciplinary team usually organized under the leadership of a physician; each member of the team has specific responsibilities and the whole team contributes to the care of the patient.Hospitals, Proprietary: Hospitals owned and operated by a corporation or an individual that operate on a for-profit basis, also referred to as investor-owned hospitals.Accreditation: Certification as complying with a standard set by non-governmental organizations, applied for by institutions, programs, and facilities on a voluntary basis.Certification: Compliance with a set of standards defined by non-governmental organizations. Certification is applied for by individuals on a voluntary basis and represents a professional status when achieved, e.g., certification for a medical specialty.Coronavirus Infections: Virus diseases caused by the CORONAVIRUS genus. Some specifics include transmissible enteritis of turkeys (ENTERITIS, TRANSMISSIBLE, OF TURKEYS); FELINE INFECTIOUS PERITONITIS; and transmissible gastroenteritis of swine (GASTROENTERITIS, TRANSMISSIBLE, OF SWINE).Coronaviridae Infections: Virus diseases caused by CORONAVIRIDAE.Camels: Hoofed mammals with four legs, a big-lipped snout, and a humped back belonging to the family Camelidae.
SARS-CoV virus causes SARS disease, and MERS-CoV virus causes Middle East respiratory syndrome (MERS) disease. Coronaviruses ... and MERS-CoV of the C lineage. MERS-CoV is the first betacoronavirus belonging to lineage C that is known to infect humans. The ... Animal viruses Human coronavirus HKU1 Human coronavirus OC43 MERS-CoV Pipistrellus Bat coronavirus HKU5 RNA virus SARS-CoV ... and MERS-CoV (various species) Lineage D includes Rousettus bat coronavirus HKU9 (BtCoV-HKU9) The viruses of lineage A differ ...
"Second Dutchman infected with lung virus MERS". NRC Handelsblad. 15 May 2014. Retrieved 17 May 2014. "Middle East respiratory ... SARS), and it has been referred to as Saudi Arabia's SARS-like virus. The first person, in June 2012, had a "seven-day history ... MERS was also implicated in an outbreak in April 2014 in Saudi Arabia, where MERS has infected 688 people and 282 MERS-related ... "Egypt detects first case of MERS virus". Press TV. 26 April 2014. Retrieved 29 April 2014. "Lebanon Records First Case of MERS ...
Until 23 May 2013, MERS-CoV had frequently been referred to as a SARS-like virus, or simply the novel coronavirus, and early it ... Lastly, South Korea was infected recently. Viruses portal European Centre for Disease Prevention and Control Novel virus ... The virus MERS-CoV is a new member of the beta group of coronavirus, Betacoronavirus, lineage C. MERS-CoV genomes are ... "MERS". healthmap.org. Emergence of the Middle East Respiratory Syndrome Coronavirus MERS-CoV Complete Genome Emerging viruses ...
The six coronaviruses known to infect humans are in the alpha and beta genera. Both MERS-CoV and SARS-CoV (severe acute ... "Death toll from new SARS-like virus climbs to 9". CNN. Retrieved 13 March 2013. "Saudi Arabia: 7 Cases of SARS-like Virus Seen ... "Second Dutchman infected with lung virus MERS". NRC Handelsblad. 15 May 2014. Retrieved 17 May 2014. "Middle East respiratory ... On May 11, 2014, two persons on Medan were suspected infected by MERS-Cov (Middle Eastern Respiratory Syndrome-Corona Virus). ...
West Nile virus, Venezuelan equine encephalitis, SARS virus, MERS coronavirus, hantaviruses, tuberculosis, typhus, Rift Valley ... Host: The organism in which the microorganism Infect. The new host must be susceptible. Source: The host from which the ... Marburg virus, Ebola virus, Lassa fever virus, Crimean-Congo hemorrhagic fever, and other hemorrhagic diseases and rishibola. ... Research work (including co-cultivation, virus replication studies, or manipulations involving concentrated virus) can be done ...
"Egyptian Virologist Who Discovered New SARS-Like Virus Fears Its Spread". Mpelembe. 13 May 2013. Pridobljeno dne 25 May 2013.. ... Emerg Infect Dis 19(11):1819-23. doi: 10.3201/eid1911.131172. *^ Wang Q, Qi J, Yuan Y, Xuan Y, Han P, Wan Y, Ji W, Li Y, Wu Y, ... Virus MERS-CoV je novi član beta skupine koronavirusov, (Beta koronavirus), linija C. Genomi MERS-cov se filogenetsko ... Virus zgleda izvira iz netopirjev.[33] Virus sam je bil izoliran iz netopirja.[34] Ta virus je tesno povezan s koronavirusom ...
Second Dutchman infected with lung virus MERS. NRC Handelsblad. 15 May 2014 [2014-05-17].. ... Holy Bat Virus! Genome Hints At Origin Of SARS-Like Virus. NPR. 2012-09-28 [2012-09-29].. ... 目前沒有藥物能夠有效地治療MERS[43]。多數的病例都是和單峰駱駝有親密接觸而受到感染,受到MERS-CoV感染的駱駝可能不會有症狀,但口鼻和臉的分泌物、奶及尿液之中仍會出現病毒顆粒[7
64 patients were infected and 5 infected patients died, the central government finally disclosed the names of MERS exposed ... On 25 June, a South Korean man who had been treated at a Chinese hospital after being diagnosed with the MERS virus in late May ... The professor also said that they were too sensitive to the outbreak because of the history of SARS in Hong Kong in 2003. ... The virus, which causes Middle East Respiratory Syndrome (MERS), was a newly emerged betacoronavirus that was first identified ...
... is the sixth coronavirus known to infect humans and the first human virus within betacoronavirus lineage C. It is ... and is not the same beta-CoV as the SARS-CoV, but is distantly related. Novel virus Middle East respiratory syndrome ... or MERS-CoV. An investigation of bat roosts in Bisha, the hometown of the index patient, by the Saudi Ministry of Health ... the beginning of another SARS-like pandemic?". J Infect. 65 (6): 477-89. doi:10.1016/j.jinf.2012.10.002. PMID 23072791. ...
"Second Dutchman infected with lung virus MERS". NRC Handelsblad. 15 May 2014. Retrieved 17 May 2014.. ... SARS), and it has been referred to as Saudi Arabia's SARS-like virus.[8] The first person, in June 2012, had a "seven-day ... MERS was also implicated in an outbreak in April 2014 in Saudi Arabia, where MERS has infected 688 people and 282 MERS-related ... "Camels in Kenya test positive for MERS virus". Informer East Africa.. *^ "MERS antibody shows promise in rabbits; signs of ...
Research in his laboratory showed that the virus induces high levels of chemicals called cytokines when it infects a type of ... SARS) coronavirus outbreak and, currently, the Middle Eastern Respiratory Syndrome (MERS) coronavirus outbreak. Original ... In 2003, Hong Kong suffered another virus outbreak, this time from an unknown respiratory disease, termed SARS. Malik became ... antibodies may play in facilitating rather than blocking the entry of viruses such as the West Nile virus and the dengue virus ...
... including many pathogens such as the hepatitis C virus, West Nile virus, dengue virus, and SARS and MERS coronaviruses, as well ... These viruses likely infect single-celled eukaryotes. There are eight families of (+)ssRNA viruses that infect vertebrates, of ... Among known (+)ssRNA viruses, only the Leviviridae are bacteriophages (that is, viruses that infect bacteria). Known ... A positive-sense single-stranded RNA virus (or (+)ssRNA virus) is a virus that uses positive sense, single-stranded RNA as its ...
Junin virus, Lassa fever virus, and MERS-coronavirus. GS-5734 was rapidly pushed through clinical trials due to the 2013-2016 ... in Infected Non-human Primates". Open Forum Infect Dis. 2. Fall 2015. doi:10.1093/ofid/ofv130.02 (inactive 2017-01-29). Warren ... BCX4430 MK-608 NITD008 Investigators also found that the drug was effective against SARS in mice, according to the study in the ... It was developed by Gilead Sciences as a treatment for filovirus infections such as Ebola virus disease and Marburg virus, ...
... suggest that the coronaviruses have been coevolved with bats for a long time and the ancestors of SARS virus first infected the ... The final name for the virus is Middle East respiratory syndrome coronavirus (MERS-CoV). In May 2015, an outbreak of MERS-CoV ... "New SARS-like virus poses medical mystery". CNN Health. Retrieved 16 March 2013. "New SARS-like virus found in Middle East". Al ... The virus was officially named the SARS coronavirus (SARS-CoV). The epidemic resulted in over 8,000 infections, about 10% of ...
64 patients were infected and 5 infected patients died,[14] the central government finally disclosed the names of MERS exposed ... On 25 June, a South Korean man who had been treated at a Chinese hospital after being diagnosed with the MERS virus in late May ... The professor also said that they were too sensitive to the outbreak because of the history of SARS in Hong Kong in 2003. ... MERS Propagation Path, infographics by KBS News (in Korean).. *Anatomy of the South Korean MERS outbreak, infographics by ...
Nipah virus, Middle East Respiratory Syndrome (MERS), Rift Valley fever, and Ebola virus, among others. Working with ... "Bat Flight and Zoonotic Viruses - Volume 20, Number 5-May 2014 - Emerging Infectious Disease journal - CDC". Emerging Infect. ... The organization has researched the emergence of diseases such as Severe Acute Respiratory Syndrome (SARS), ... On an evolutionary scale, this host-virus interaction might have resulted in the large diversity of zoonotic viruses in bats, ...
Among the seven to ten specific viral mRNAs synthesized in virus-infected cells, only the full-length genomic RNA is packaged ... "MERS-CoV , Symptoms and Complications of MERS , Coronavirus , CDC". www.cdc.gov. Retrieved 2016-12-07. "MERS-CoV , About MERS ... Human infection by SARS coronavirus appears to be limited to the respiratory tract where infection of susceptible cells leads ... Many aspects of MERS are still being researched. Scientist have recently found that the cellular receptor for MERS-CoV is CD24 ...
SARS-CoV-2 (engelsk Severe acute respiratory syndrome coronavirus 2) er eit nytt virus som først blei isolert frå tre menneske ... Saey, Tina Hesman (24 January 2020). «How the new coronavirus stacks up against SARS and MERS». Arkivert frå originalen 25 ... Int J Infect Dis. 2020 Jan 14;91:264-266. doi:10.1016/j.ijid.2020.01.009. PMID 31953166. ... SARS-CoV-2 er nært i slekt med SARS-CoV, viruset som valdar SARS hjå menneske.[110] Ein reknar med at det er zoonotisk. ...
MERS, and SARS Viruses" (PDF). Berg, Paul (14 September 2012). "The Dual-Use Conundrum". Science. 337 (6100): 1273. doi:10.1126 ... A scientist claims she was infected by a genetically modified virus while working for Pfizer. In her federal lawsuit she says ... Genetically-modified virus explodes cancer cells GM virus shrinks cancer tumours in humans Leja, J.; Yu, D.; Nilsson, B.; Gedda ... Viruses that have been used for gene therapy are, adenovirus, lentivirus, retrovirus and the herpes simplex virus. Although ...
MERS in Saudi Arabia (2018). *Kerala Nipah virus (2018). *Équateur province Ebola (2018) ... Pneumonic plague occurs when plague infects the lungs and is transmissible person to person through infected droplets. This ... During this plague season, rats and fleas infect the soil. Evolution of bacteria[edit]. Scientists discovered three new strains ... Plague is caused by the bacterium Yersinia pestis and is most commonly transmitted through infected fleas.[20] There are three ...
MERS virus claims two more lives in Saudi Arabia, 7. september 2013 (vaadatud 12.09.2013) (inglise keeles) ... MERS-CoV) - possible lessons from a systematic review of SARS-CoV therapy, International Journal of Infectious Diseases, 17. ... Mohammed N. Al-Ahdal, Ahmed A. Al-Qahtani, Salvatore Rubino, Coronavirus respiratory illness in Saudi Arabia, J Infect Dev ... MERS-i ravi[muuda , muuda lähteteksti]. MERS-i ravi seni puudub. MERS-i-patsient saab vastavalt sümptomitele nn toetavat ravi. ...
Genus Betacoronavirus - Subgenera: Embecovirus, Hibecovirus, Merbecovirus (mit MERS-CoV), Nobecovirus, Sarbecovirus (mit SARS- ... a Newly Identified Virus Infecting the Pea Aphid, in: J Invertebr Pathol. November/Dezember 1997;70(3):169-76., doi:10.1006/ ... Usutu-Virus - en. Usutu virus (USUV), Zika-Virus - en. Zika virus (ZIKV), sowie Gelbfieber-Virus - en. Yellow fever virus (YFV) ... Genus ‚Negevirus', mit Species ‚Blackford virus', ‚Bofa virus', ‚Buckhurst virus', ‚Marsac virus', sowie ‚Muthill virus'[53] ...
Saudi Arabian MERS (2018). *Kerala Nipah virus (2018). *Équateur province Ebola (2018) ... As the disease swept north to the Rhine, it also infected Germanic and Gallic peoples outside the empire's borders. For years, ... "Origin of measles virus: divergence from rinderpest virus between the 11th and 12th centuries.", Virol. J., 7 (52). ... "Origin of the Measles Virus: Divergence from Rinderpest Virus Between the 11th and 12th Centuries". Virology. 7: 52-55. doi ...
MERS coronavirus bats, camels close contact Monkeypox Monkeypox virus rodents, primates contact with infected rodents, primates ... Saint Louis encephalitis virus birds mosquito bite Severe acute respiratory syndrome SARS coronavirus bats, civets close ... Nipah virus infection Nipah virus (NiV) bats, pigs direct contact with infected bats, infected pigs ... Eastern equine encephalitis virus, Venezuelan equine encephalitis virus, Western equine encephalitis virus horses, donkeys, ...
Junin virus, Lassa fever virus, and MERS-coronavirus.[1] Remdesivir was rapidly pushed through clinical trials due to the 2013- ... in Infected Non-human Primates". Open Forum Infect Dis. 2. doi:10.1093/ofid/ofv130.02.. ... Investigators also found that the drug was effective against SARS in mice, according to the study in the June 28 issue of the ... It was developed by Gilead Sciences as a treatment for Ebola virus disease and Marburg virus infections, though it has ...
RNA virus. *IV: SARS coronavirus *Severe acute respiratory syndrome. *MERS coronavirus *Middle East respiratory syndrome ... Kuniholm MH & Nelson KE (2008). "Of Organ Meats and Hepatitis E Virus: One Part of a Larger Puzzle Is Solved". J Infect Dis. ... DNA virus. HBV (B). RNA virus. CBV. HAV (A). HCV (C). HDV (D). HEV (E). HGV (G). ... DNA virus. Human polyomavirus 2 Progressive multifocal leukoencephalopathy. RNA virus. MeV Subacute sclerosing panencephalitis ...

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