A genus of the family CORONAVIRIDAE which causes respiratory or gastrointestinal disease in a variety of vertebrates.
A species of CORONAVIRUS causing atypical respiratory disease (SEVERE ACUTE RESPIRATORY SYNDROME) in humans. The organism is believed to have first emerged in Guangdong Province, China, in 2002. The natural host is the Chinese horseshoe bat, RHINOLOPHUS sinicus.
A viral disorder characterized by high FEVER, dry COUGH, shortness of breath (DYSPNEA) or breathing difficulties, and atypical PNEUMONIA. A virus in the genus CORONAVIRUS is the suspected agent.
Virus diseases caused by the CORONAVIRUS genus. Some specifics include transmissible enteritis of turkeys (ENTERITIS, TRANSMISSIBLE, OF TURKEYS); FELINE INFECTIOUS PERITONITIS; and transmissible gastroenteritis of swine (GASTROENTERITIS, TRANSMISSIBLE, OF SWINE).
A class I viral fusion protein that forms the characteristic spikes, or peplomers, found on the viral surface that mediate virus attachment, fusion, and entry into the host cell. During virus maturation, it is cleaved into two subunits: S1, which binds to receptors in the host cell, and S2, which mediates membrane fusion.
A species in the genus CORONAVIRUS causing upper and lower RESPIRATORY TRACT INFECTIONS. It shares the receptor used by the SARS VIRUS.
A species in the genus CORONAVIRUS causing the common cold and possibly nervous system infections in humans. It lacks hemagglutinin-esterase.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
A mutant strain of TRANSMISSIBLE GASTROENTERITIS VIRUS causing mild or subclinical respiratory infections in young SWINE. It may also play a role in post-weaning porcine respiratory disease complex, especially when combined with other respiratory agents.
A neoplasm composed entirely of GRANULOSA CELLS, occurring mostly in the OVARY. In the adult form, it may contain some THECA CELLS. This tumor often produces ESTRADIOL and INHIBIN. The excess estrogen exposure can lead to other malignancies in women and PRECOCIOUS PUBERTY in girls. In rare cases, granulosa cell tumors have been identified in the TESTES.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
Hoofed mammals with four legs, a big-lipped snout, and a humped back belonging to the family Camelidae.
Order of mammals whose members are adapted for flight. It includes bats, flying foxes, and fruit bats.
A species in the genus CORONAVIRUS causing the common cold and possibly nervous system infections in humans. It contains hemagglutinin-esterase.
A group of deoxyribonucleotides (up to 12) in which the phosphate residues of each deoxyribonucleotide act as bridges in forming diester linkages between the deoxyribose moieties.
Viral proteins found in either the NUCLEOCAPSID or the viral core (VIRAL CORE PROTEINS).
The region of southwest Asia and northeastern Africa usually considered as extending from Libya on the west to Afghanistan on the east. (From Webster's New Geographical Dictionary, 1988)
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
Virus diseases caused by CORONAVIRIDAE.
Spherical RNA viruses, in the order NIDOVIRALES, infecting a wide range of animals including humans. Transmission is by fecal-oral and respiratory routes. Mechanical transmission is also common. There are two genera: CORONAVIRUS and TOROVIRUS.
Polymers made up of a few (2-20) nucleotides. In molecular genetics, they refer to a short sequence synthesized to match a region where a mutation is known to occur, and then used as a probe (OLIGONUCLEOTIDE PROBES). (Dorland, 28th ed)
Layers of protein which surround the capsid in animal viruses with tubular nucleocapsids. The envelope consists of an inner layer of lipids and virus specified proteins also called membrane or matrix proteins. The outer layer consists of one or more types of morphological subunits called peplomers which project from the viral envelope; this layer always consists of glycoproteins.
A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).
A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.
The spatial arrangement of the atoms of a nucleic acid or polynucleotide that results in its characteristic 3-dimensional shape.
Disruption of the secondary structure of nucleic acids by heat, extreme pH or chemical treatment. Double strand DNA is "melted" by dissociation of the non-covalent hydrogen bonds and hydrophobic interactions. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible.
A species of the CORONAVIRUS genus causing hepatitis in mice. Four strains have been identified as MHV 1, MHV 2, MHV 3, and MHV 4 (also known as MHV-JHM, which is neurotropic and causes disseminated encephalomyelitis with demyelination as well as focal liver necrosis).
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)
Polymers synthesized by living organisms. They play a role in the formation of macromolecular structures and are synthesized via the covalent linkage of biological molecules, especially AMINO ACIDS; NUCLEOTIDES; and CARBOHYDRATES.
Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin.
A CELL LINE derived from the kidney of the African green (vervet) monkey, (CERCOPITHECUS AETHIOPS) used primarily in virus replication studies and plaque assays.
A species of CERCOPITHECUS containing three subspecies: C. tantalus, C. pygerythrus, and C. sabeus. They are found in the forests and savannah of Africa. The African green monkey (C. pygerythrus) is the natural host of SIMIAN IMMUNODEFICIENCY VIRUS and is used in AIDS research.
Pairing of purine and pyrimidine bases by HYDROGEN BONDING in double-stranded DNA or RNA.
Glycoproteins found on the membrane or surface of cells.
Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.
Established cell cultures that have the potential to propagate indefinitely.
Ribonucleic acid that makes up the genetic material of viruses.
The parts of a macromolecule that directly participate in its specific combination with another molecule.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
Methods used for studying the interactions of antibodies with specific regions of protein antigens. Important applications of epitope mapping are found within the area of immunochemistry.
A peptidyl-dipeptidase that catalyzes the release of a C-terminal dipeptide, -Xaa-*-Xbb-Xcc, when neither Xaa nor Xbb is Pro. It is a Cl(-)-dependent, zinc glycoprotein that is generally membrane-bound and active at neutral pH. It may also have endopeptidase activity on some substrates. (From Enzyme Nomenclature, 1992) EC 3.4.15.1.
Immunoglobulins produced in response to VIRAL ANTIGENS.
The complete genetic complement contained in a DNA or RNA molecule in a virus.
A polynucleotide consisting essentially of chains with a repeating backbone of phosphate and ribose units to which nitrogenous bases are attached. RNA is unique among biological macromolecules in that it can encode genetic information, serve as an abundant structural component of cells, and also possesses catalytic activity. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are linear polypeptides that are normally synthesized on RIBOSOMES.
Short fragments of DNA or RNA that are used to alter the function of target RNAs or DNAs to which they hybridize.
A natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. It is found in the UMBILICAL CORD, in VITREOUS BODY and in SYNOVIAL FLUID. A high urinary level is found in PROGERIA.
A change from planar to elliptic polarization when an initially plane-polarized light wave traverses an optically active medium. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A rigorously mathematical analysis of energy relationships (heat, work, temperature, and equilibrium). It describes systems whose states are determined by thermal parameters, such as temperature, in addition to mechanical and electromagnetic parameters. (From Hawley's Condensed Chemical Dictionary, 12th ed)
Devices or objects in various imaging techniques used to visualize or enhance visualization by simulating conditions encountered in the procedure. Phantoms are used very often in procedures employing or measuring x-irradiation or radioactive material to evaluate performance. Phantoms often have properties similar to human tissue. Water demonstrates absorbing properties similar to normal tissue, hence water-filled phantoms are used to map radiation levels. Phantoms are used also as teaching aids to simulate real conditions with x-ray or ultrasonic machines. (From Iturralde, Dictionary and Handbook of Nuclear Medicine and Clinical Imaging, 1990)
Proteins found in any species of bacterium.
The relationships of groups of organisms as reflected by their genetic makeup.
The relative amounts of the PURINES and PYRIMIDINES in a nucleic acid.
Suspensions of attenuated or killed viruses administered for the prevention or treatment of infectious viral disease.
Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.
The process of intracellular viral multiplication, consisting of the synthesis of PROTEINS; NUCLEIC ACIDS; and sometimes LIPIDS, and their assembly into a new infectious particle.
A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.
The rate dynamics in chemical or physical systems.
The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.
The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.
Carbohydrates consisting of between two (DISACCHARIDES) and ten MONOSACCHARIDES connected by either an alpha- or beta-glycosidic link. They are found throughout nature in both the free and bound form.
The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).
Sites on an antigen that interact with specific antibodies.
Proteins found in any species of virus.
The process by which a DNA molecule is duplicated.
Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.
An imaging technique using compounds labelled with short-lived positron-emitting radionuclides (such as carbon-11, nitrogen-13, oxygen-15 and fluorine-18) to measure cell metabolism. It has been useful in study of soft tissues such as CANCER; CARDIOVASCULAR SYSTEM; and brain. SINGLE-PHOTON EMISSION-COMPUTED TOMOGRAPHY is closely related to positron emission tomography, but uses isotopes with longer half-lives and resolution is lower.
Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.
Partial proteins formed by partial hydrolysis of complete proteins or generated through PROTEIN ENGINEERING techniques.
The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.
The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.
Deoxyribonucleic acid that makes up the genetic material of bacteria.
Processes involved in the formation of TERTIARY PROTEIN STRUCTURE.
The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.
Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.
Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.
An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers.
Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.
Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
"WHO , MERS-CoV". WHO. Retrieved 19 October 2020. Robert Herriman (17 July 2013). "MERS does not constitute a Public Health ... David R Curry (20 July 2013). "WHO Statement: Second Meeting of the IHR Emergency Committee concerning MERS-CoV - PHEIC ... "WHO , Middle East respiratory syndrome coronavirus (MERS-CoV) - Saudi Arabia". WHO. Retrieved 19 October 2020. "Can the ... PHEIC was not invoked with the Middle Eastern Respiratory Syndrome (MERS) outbreak in 2013. Originating in Saudi Arabia, MERS ...
"MERS-CoV found in bat; hunt for other sources goes on , CIDRAP". Cidrap.umn.edu. 2013-08-21. Retrieved 2013-09-15. Koopman, ... An isolate of the MERS-CoV from the first patient identified was found in an Egyptian tomb bat near the victim's home in Saudi ...
MERS-CoV) infection. Collaborative efforts were used in the identification of the MERS-CoV. Egyptian virologist Dr. Ali Mohamed ... "MERS outbreaks". www.emro.who.int. Retrieved 7 February 2021. "MERS-CoV , Interim Guidelines for Clinical Specimens from PUI , ... Middle East respiratory syndrome is caused by the MERS coronavirus (MERS-CoV), a species with single-stranded RNA belonging to ... "Saudi Arabia: Farmers flout Mers warning by kissing camels". BBC News. 13 May 2014. Retrieved 22 May 2014. The Who Mers-Cov ...
Even the Middle East respiratory syndrome coronavirus (MERS-CoV) that was first identified in Saudi Arabia last year, it has ... ISBN 978-0-19-509305-6. Petherick, A (Jun 15, 2013). "MERS-CoV: in search of answers". Lancet. 381 (9883): 2069. doi:10.1016/ ... But MERS is not yet a pandemic, could become pervasive in genetic disease patient. Dr Thurman' guidebook about Rare genetic ...
In a press release on April 19, DOH announced that the OFW who was found by UAE doctors positive of MERS-CoV was found negative ... April 16 - An OFW who returned from Al Ain City, United Arab Emirates was found positive of the MERS-CoV at the Ninoy Aquino ... Ira Pedrasa (April 14, 2014). "DFA confirms OFW death in UAE due to MERS-CoV". ABS-CBN News. Retrieved April 14, 2014. Bong ... Nina Corpuz (April 29, 2014). "MERS-CoV remains a threat in PH". ABS-CBN News. Retrieved April 29, 2014. Rie Takumi (May 15, ...
"Middle East respiratory syndrome coronavirus (MERS-CoV)". www.who.int. 11 March 2019. Retrieved 2020-04-30. "MERS (Middle East ... In 2017, experimental infections of dromedaries with MERSCoV didn't show any evidence of virus in the urine. Therefore, the ... "Middle East respiratory syndrome coronavirus (MERS-CoV) - Qatar". World Health Organization. 12 March 2020. Retrieved 1 May ... MERS-CoV)". Transboundary and Emerging Diseases. 64 (2): 344-353. doi:10.1111/tbed.12401. ISSN 1865-1682. PMC 4749478. PMID ...
Animal viruses MERS-CoV Corman, V. M.; Kallies, R.; Philipps, H.; Gopner, G.; Muller, M. A.; Eckerle, I.; Brunink, S.; Drosten ...
MERS-CoV)". WHO. Retrieved 15 April 2020. Sharif-Yakan A, Kanj SS (December 2014). "Emergence of MERS-CoV in the Middle East: ... MERS-CoV is believed to have been circulating in these mammals for over 20 years, and it is thought that novel camel farming ... practices drove the spillover of MERS-CoV into humans. Studies have shown that humans can be infected with MERS-CoV via direct ... MERS-CoV gains cellular entry by using a spike surface protein to bind to the host DPP4 surface receptor; the core subdomain of ...
In 2013, he contributed to research on MERS-CoV during the first MERS outbreak in the Middle East, and its link with dromedary ... ISBN 978-0-10-844484-5. Roos, Robert (16 December 2013). "Nearly identical MERS-CoV strains found in camels, humans". CIDRAP. ... Ferguson, Neil M; Van Kerkhove, Maria D (2014). "Identification of MERS-CoV in dromedary camels". The Lancet Infectious ... Identification of MERS-CoV in dromedary camels Infectious disease: Tough choices to reduce Ebola transmission Modeling the ...
These zoonotic viruses include the rabies virus, SARS-CoV, MERS-CoV, Marburg virus, Nipah virus, and Hendra virus. While ... of coronaviruses SARS-CoV, MERS-CoV, and beyond". Trends in Microbiology. 23 (8): 468-478. doi:10.1016/j.tim.2015.06.003. PMC ... MERS-CoV). Severe acute respiratory syndrome coronavirus 2 is another zoonotic coronavirus likely originating in bats. SARS-CoV ... It is believed that MERS-CoV originated in bats, though camels are likely the intermediate host through which humans became ...
Identification of MERS-CoV in dromedary camels. . In: The Lancet. Infectious Diseases. . Jg. 14, Nr. 2, Dezember 2013. ... Im Jahre 2013 wurde sie Mitglied der MERS-CoV-Task-Force der WHO.[8] Seit 2015 ist Van Kerkhove als Ehrendozentin am Imperial ... Sie spezialisierte sich auf Ebolafieber, Grippe, Meningitis, MERS-CoV und Gelbfieber und stand seit April 2009 der WHO als ... MERS-CoV). World Health Organization, abgerufen am 1. Mai 2020. *↑ Institut Pasteur OMI Seminar in Salzburg: "Pandemics". ...
"Broad-Spectrum Antiviral Effective Against Ebola, MERS-CoV". Global Biodefense. March 3, 2014. Retrieved January 9, 2021. "HHS ... is a broad-spectrum antiviral in advanced development for the treatment of viruses including SARS-CoV-2 (the cause of COVID-19 ...
"DOH reports new MERS-CoV case in PHL". GMA News. July 6, 2015. Retrieved July 6, 2015. "DOH confirms first MERS-CoV case in the ... July 6 - DOH confirmed the second detected case of MERS-CoV in the country. The patient who had contracted the virus was from ... Jocelyn R. Uy (February 17, 2015). "All persons exposed to nurse with MERS-CoV test negative for virus - DOH". Philippine Daily ... "3 Pinoys infected with MERS-CoV in Saudi -DFA". GMA News. March 6, 2015. Retrieved March 6, 2015. Geronimo, Jee Y. (February 19 ...
MERS-CoV), a more deadly, SARS-CoV-2-like species of betacoronavirus. Televangelist Kenneth Copeland urged followers to touch ... "Middle East respiratory syndrome coronavirus (MERS-CoV) - Saudi Arabia". World Health Organization. May 5, 2020. Retrieved May ... "Middle East respiratory syndrome coronavirus (MERS-CoV) - Qatar". World Health Organization. March 12, 2020. Retrieved May 8, ... MERS-CoV) - Republic of Korea". WHO. Woodward, Alex (April 5, 2020). "Televangelist 'blows wind of God' at coronavirus". The ...
"Queensland tapped by US to develop MERS-CoV antibody". Queensland Health. 5 June 2015. Retrieved 6 October 2015.. ...
MERS-CoV)" (PDF). EDCE Risk Assessment. 1: 1-11. "New case of MERS-CoV identified in the United Kingdom". European Centre for ... MERS-CoV). The cases were most numerous in, and are believed to have originated from, Saudi Arabia. 250 cases of MERS were ... MERS-CoV) - Saudi Arabia". World Health Organization. Retrieved 2018-09-13. "First case of deadly MERS virus in five years ... MERS) www.emro.who.int, accessed 29 January 2020 "Rapid Risk Assessment: Middle East respiratory syndrome coronavirus (MERS-CoV ...
"Novel coronavirus update - new virus to be called MERS-CoV". World Health Organization Regional Office for Europe. May 16, 2013 ... The World Health Organization names the novel coronavirus Middle East respiratory syndrome (MERS). May 20 - A large and ...
The MERS-CoV outbreak in South Korea in 2015 also seriously hampered filming schedules. The outbreak claimed the lives of 33 ... "Middle East respiratory syndrome coronavirus (MERS-CoV) - Republic of Korea". World Health Organization. July 3, 2015. "Let's ...
The two viruses studied included MERS-CoV and SARS-CoV. Though this was an important discovery, neither enzyme can be used as a ... MERS-CoV) The article shows that differe coronaviruses work the same way, but are not the same efficiency. ... It was found that an adjacent Ubl domain was present in different CoV domains. Structural Basis for the Ubiquitin-Linkage ... Specificity and deISGylating Activity of SARS-CoV Papain-Like Protease This article shows the basis of the ubiquitin chain of ...
In 2013, she was a technical consultant for WHO as a member of the MERS-CoV task force. From 2015 to 2017, Van Kerkhove was the ... She has been Scientist, Technical Lead MERS-CoV at WHO in Geneva, Switzerland, since March 2017. As part of her work with WHO, ... She specialized in Ebola, influenza, meningitis, MERS-CoV, and yellow fever. In April 2009, she began working as a technical ... MERS-CoV, Ebola and Marburg. She specialized in field research to gather data on the highly pathogenic avian influenza H5N1 ( ...
"DOH reports new MERS-CoV case in PHL". GMA News. 6 July 2015. Retrieved 6 July 2015. "DOH confirms first MERS-CoV case in the ... Both MERS-CoV and SARS-CoV (severe acute respiratory syndrome) are betacoronaviruses. Global surveillance of potential ... MERS-CoV) - update". World Health Organization. 23 April 2014. Retrieved 23 April 2014. "Iran: MERS Virus Reaches Its 20th ... In a press release on 19 April, DOH announced that the OFW who UAE doctors found positive for MERS-CoV was found negative for ...
... mit MERS-CoV), Nobecovirus, Sarbecovirus (mit SARS-CoV) ...
August 2017). "Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen". Proceedings of the ... the first SARS-CoV-2 viral genomes were shared via GISAID on 10 January 2020 Thanh Le T, Andreadakis Z, Kumar A, Gómez Román R ... It is composed of nucleoside-modified mRNA (modRNA) encoding a mutated form of the full-length spike protein of SARS-CoV-2, ... The Pfizer-BioNTech COVID-19 vaccine is used to provide protection against infection by the SARS-CoV-2 virus in order to ...
I 2003 oppdaget man en ny variant, SARS-CoV. Flere lignende varianter, som MERS-CoV i 2012 (oppdaget i Midtøsten), og SARS-CoV- ... Fram til 2019 var 2468 tilfeller av MERS-CoV oppdaget, og 851 var døde som følge av dette svært farlige viruset. MERS-CoV ... Rapid advice note on home care for patients with Middle East respiratory syndrome coronavirus (MERS-CoV) infection presenting ... I september 2012 ble en ny variant, MERS-CoV oppdaget, som forårsaket 52 dødsfall i Saudi-Arabia i 2013. ...
MERS-CoV).[55] A 2013-14 study of dromedaries in Saudi Arabia concluded the unusual genetic stability of MERS-CoV coupled with ... match to the genomes of human clade B MERS-CoV.[56] Another study in Saudi Arabia showed the presence of MERS-CoV in 90% of the ... 3D image of MERS-CoV, of which the dromedary is possibly the animal source ... The full genome sequence of MERS-CoV from dromedaries in this study showed a 99.9% ...
"Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD". Cell Reports. 28 (13): 3395-3405.e6. doi: ... "A high-throughput inhibition assay to study MERS-CoV antibody interactions using image cytometry". Journal of Virological ... transplanted stabilizing mutations from SARS-CoV S protein into SARS-CoV-2 spike protein. She was part of the NIH team who ... MERS) vaccine antigens. During this time, she identified a simple way to make spike proteins that are stabilized in a ...
MERS-CoV) and Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2), the aetiological agent of the COVID-19 ... namely SARS-CoV and SARS-CoV-2. SARS-CoV emerged as an acute respiratory syndrome in Guangdong Province, southern China, during ... WHO referred to the virus as the Middle East respiratory syndrome coronavirus (MERS-CoV) on 23 May 2013. ICTV announced the ... MERS-CoV): announcement of the Coronavirus Study Group". Journal of Virology. 87 (14): 7790-7792. doi:10.1128/JVI.01244-13. ...
"Geographical distribution of confirmed MERS-CoV cases by country of infection and year". European Centre for Disease Prevention ...
Teicoplanin, SARS-CoV-2'yi ve akrabası olduğu MERS koronavirüslerini inhibe etmekte olup, COVID-19 tedavisi için potansiyel bir ... SARS-CoV-2 orijinal SARS-CoV ile yakından bağlantılıdır.[15] Hayvan kökenli olduğu düşünülmektedir (zoonotik). Genetik ... SARS-CoV-2'nin M proteini, yarasa SARS-CoV'nin M proteinine %98,6 benzerdir, pangolin SARS-CoV ile %98,2 homolojiyi korur ve ... U07.1 kodu SARS-CoV-2 enfeksiyon nedeniyle gerçekleşmiş labratuvarlarca onaylanmış ölümleri, U07.2 ise SARS-CoV-2 enfeksiyonu ...
Her research considers the biology of coronaviruses, including SARS, MERS and SARS-CoV-2. As of March 2020, Weiss serves as Co- ... The Center looks to accelerate research that focusses on SARS-CoV-2, become a centralised repository of SARS-CoV-2 research and ... Whilst MERS has a viral reservoir in camels and may have been transmitted to humans via camel handlers, SARS does not have such ... create new opportunities to fund research relating to SARS-CoV-2. SARS-CoV-2 is different to SARS; as there are many people who ...
MERS coronavirus bats, camels close contact Monkeypox Monkeypox virus rodents, primates contact with infected rodents, primates ... severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) bats, pangolins, felines, minks respiratory transmission 2019 ...
"We had previous experience on SARS-CoV in 2003 and MERS-CoV in 2014. These two viruses, which are closely related to SARS-CoV-2 ... The scientists measured the amount of antibodies and guessed it would be enough to fight off the SARS-CoV-2 virus if the mice ... The team took the spike protein from SARS-CoV-2 and put it on an adenovirus. Then they injected that virus into test patients. ... The nose and mouth are where most people are infected with SARS-CoV-2. Scientists are not sure why this works. As of July 2020 ...
Middle East Respiratory Syndrome coronavirus (MERS-CoV) - Saudi Arabia. World Health Organisation (2015-06-11). Retrieved on ...
Bližšie informácie v hlavnom článku: SARS-CoV-2. SARS-CoV-2 (predtým 2019-CoV) je betakoronavírus, patriaci do širokej skupiny ... Pacienti sú liečení symptomaticky, s prihliadnutím na skúsenosti z minulých koronavírusových epidémii SARS a MERS. V ťažkých ... Bližšie informácie v hlavnom článku: Pandémia koronavírusu SARS-CoV-2. SARS-CoV-2 spôsobil začiatkom roka 2020 epidémiu, ktorá ... COVID-19[1][2] (z angl. CoronaVirus Disease) je infekčné ochorenie, vyvolané koronavírusom SARS-CoV-2 (Severe Acute Respiratory ...
"How Does Wuhan Coronavirus Compare with MERS, SARS and the Common Cold?". NPR. Tinago mula sa orihinal noong 2 February 2020. ... Ang SARS-CoV-2 (mula sa Ingles: Severe acute respiratory syndrome coronavirus 2),[1][2] na dating kilala bilang 2019 novel ... 501.V2 variant - o '20C/501Y.V2, B.1.351 lineage' ang baryant na ito ay nakita sa Timog Aprika baryante ng SARS-CoV-2 na nag ... Variant of Concern 202012/01 o 'B117' ay isa sa tatlong baryant ng SARS-CoV-2 na sanhi ng COVID-19 na unang nakita noong ...
Aproveitáronse tamén os traballos previos sobre o SARS-CoV con este fin porque o SARS-CoV-2 e o SARS-CoV usan ambos o receptor ... MERS), pero carécense de datos suficientes para a COVID-19.[182][183] ... Artigo principal: SARS-CoV-2.. A enfermidade é causada polo virus SARS-CoV-2, previamente denominado 2019-nCoV,[44] que se ... marzo de 2020). "Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1". The New England Journal of Medicine ...
MERS = Middle East respiratory syndrome eller kamel-influenza forårsages af MERS-coronavirus MERS-CoV med proteinkappe og et ... SARS eller akut luftvejssyndrom forårsages af SARS-CoV, en Coronavirus med proteinkappe og et genom af +ssRNA med omkring ... COVID-19 forårsages af SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2, en Coronavirus med membrankappe, ... a b How does SARS-CoV-2 cause COVID-19?. Science 2020 ...
... e o recentemente identificado MERS-CoV únese á dipeptidil-peptidase 4 (DPP4) para conseguir entrar en células humanas (Ver ... SARS-CoV, o virus que causa o SARS,[12][13][14] e o SARS-CoV-2,[15] o virus que causa a COVID-19.[16][17][18][19] ... SARS-CoV-2. Ligazóns externas[editar , editar a fonte]. *Localización no xenoma humano de ACE2 e páxina con detalles sobre o ... Moitos α-coronavirus utilizan a aminopeptidase N (APN) como o seu receptor, o SARS-CoV e o HCoV-NL63 usan o enzima conversor da ...
Tila may kaugnayan ang SARS-CoV-2 sa orihinal na SARS-CoV.[60] Ipinapalagay na nanggaling ito sa hayop. Isinisiwalat ng pag- ... tulad ng SARS at MERS, ngunit kulang ang mga datos para sa COVID-19.[176][177] ... ay isang nakakahawang sakit dulot ng SARS-CoV-2, isang birus na may kaugnayan sa SARS-CoV.[6][7] Naitala ang mga unang kaso ... Ang SARS-CoV-2 ay isang novel severe acute respiratory syndrome coronavirus, unang ibinukod mula sa tatlong tao na may pulmonya ...
ತೀವ್ರ ಉಸಿರಾಟದ ತೊಂದರೆಯ ಕೊರೊನಾವೈರಸ್-೨ ( SARS-CoV-2 ),[೧] ಹಿಂದೆ ತಾತ್ಕಾಲಿಕ ಹೆಸರಿನಿಂದ ೨೦೧೯ರ ನೊವೆಲ್ ಕೊರೊನಾವೈರಸ್ ( 2019-nCoV ),[೨][೩] ... "How Does Wuhan Coronavirus Compare with MERS, SARS and the Common Cold?". NPR. 22 January 2020. Archived from the original on 2 ... SARS-CoV-2 ಅನ್ನು ತೀವ್ರ ಉಸಿರಾಟದ ತೊಂದರೆಯ ಕೊರೊನಾವೈರಸ್-ಸಂಬಂಧಿತ ಕೊರೊನಾವೈರಸ್ (SARSr-CoV) ಜಾತಿಯ ವೈರಸ್ ಎಂದು ವರ್ಗೀಕರಿಸಲಾಗಿದೆ . ... SARS-CoV-2 ಬ್ಯಾಟ್ ಕರೋನವೈರಸ್ಗಳಿಗೆ ನಿಕಟ ಆನುವಂಶಿಕ ಹೋಲಿಕೆಯನ್ನು ಹೊಂದಿದೆ, ಅದು ಹುಟ್ಟಿಕೊಂಡಿರಬಹುದು .[೮][೯][೧೦] ಪ್ಯಾಂಗೊಲಿನ್ ನಂತಹ ...
Tila may kaugnayan ang SARS-CoV-2 sa orihinal na SARS-CoV.[60] Ipinapalagay na nanggaling ito sa hayop. Isinisiwalat ng pag- ... tulad ng SARS at MERS, ngunit kulang ang mga datos para sa COVID-19.[176][177] ... Nakahahawang sakit sa paghinga na dulot ng SARS-CoV-2Padron:SHORTDESC:Nakahahawang sakit sa paghinga na dulot ng SARS-CoV-2 ... ay isang nakakahawang sakit dulot ng SARS-CoV-2, isang birus na may kaugnayan sa SARS-CoV.[6][7] Naitala ang mga unang kaso ...
MERS-CoV)". World Health Organization.. *^ Jack, A (2015). "Why the panic? South Korea's MERS response questioned". BMJ. 350: ... "Middle East respiratory syndrome coronavirus (MERS-CoV)". World Health Organization.. *^ (in Chinese). "疑中招韓男隱瞞病歷經港往惠州新沙士殺到". 蘋 ... MERS-CoV; Middle East respriatory syndrome coronavirus, HCW; health-care worker The number in circle indicated patient's case ... "Middle East respiratory syndrome coronavirus (MERS-CoV) - Republic of Korea". World Health Organization. Retrieved 2016-12-01
Transmission electron micrograph of several MERS-CoV virions, a close relative of 2019 nCov. ... SARS-CoV-2),[3][4] යනු, පෙරදී 2019 නව කොරෝනාවෛරසය [5](2019-එන්කොවී)[6] යන තාවකාලික නම මගින් හැඳින්වුනු ,[7] ධන-අභිදිශා තනි-පට ... "The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2". Nature ...
MERS-CoV nakkuse tuvastamine[muuda , muuda lähteteksti]. MERS-CoV viirust on võimalik rögaroovides 'välja kasvatada', kasutades ... MERS-i kliiniline pilt[muuda , muuda lähteteksti]. MERS-CoV põhjustab sagedamini ülemiste ja harvemini alumiste hingamisteede ... MERS-i ravi[muuda , muuda lähteteksti]. MERS-i ravi seni puudub. MERS-i-patsient saab vastavalt sümptomitele nn toetavat ravi. ... aasta MERS-i haiguspuhang Jiddah's. *7 2015. aasta MERS-i haiguspuhang Lõuna-Koreas *7.1 Üksikud MERS-i haigusjuhud maailmas ...
İlaç, SARS-CoV-2 ile Nipah ve Hendra virüs enfeksiyonlarında kullanımı için araştırma altındadır.[4][5][6] Diğer koronavirüs ... MERS ve SARS virüsleri dahil) yer aldığı diğer tek sarmallı RNA virüslerine karşı antivirütik aktivite gösterebildikleri ... enfeksiyonlarına karşı başarı göstermiş oldğundan ötürü Gilead, SARS-CoV-2 enfeksiyonlarına karşı Amerika'da doktorlara ilacı ...
MERS-CoV) ne-Severe Acute Respiratory Syndrome (SARS-CoV). Uhlobo olusha lwalamagciwane i-(SARS-COV-2) idala i-COVID-19.[12] ... Uphenyo olujulile luthole ukuthi i-SARS-COV yangena ebantwini ngamakati, bese kuthi i-MERS-CoV yangena ebantwini ngamakameli. ...
MERS-CoV)[18],有別於嚴重急性呼吸系統綜合症冠狀病毒和普通傷風冠狀病毒。[19]中東冠狀病毒具單鏈核糖核酸,為 β 冠狀病毒屬的新成員,按基因組區別被分為了甲、乙兩大系統發生分支;最早期的感染病例是由甲類病毒造成,與後來的不同。[20] ... 目前沒有藥物能夠有效地治療MERS[43]。多數的病例都是和單峰駱駝有親密接
MERS-CoV saguzarretatik eratorritako betakoronavirus bat da. Gameluek MERS-CoV antigorputzak dituztela frogatu ahal izan da, ... MERS koronabirusak (MERS-CoV) eragindako epidemia bat da. Sintomak arinetik larrietara izan litzazke, tartean sukarra, eztula, ... Ekialde Ertaineko arnas sindromea edo gamelu gripea, ingelesez: Middle East respiratory syndrome edo MERS, ...
MERS-CoV. *SARS-related coronavirus *SARS-CoV. *SARS-CoV-2. Primate. -borne. ...
MERS-CoV is a betacoronavirus derived from bats.[2] Camels have been shown to have antibodies to MERS-CoV but the exact source ... "MERS death count up to 29". HiDoc. 25 June 2015.. *^ "Middle East respiratory syndrome coronavirus (MERS-CoV) summary and ... "MERS-CoV , Prevention and Treatment of MERS , Coronavirus , CDC". www.cdc.gov. 13 July 2016. Retrieved 4 April 2017.. ... Middle East respiratory syndrome is caused by the newly identified MERS coronavirus (MERS-CoV), a species with single-stranded ...
Virus MERS-CoV je novi član beta skupine koronavirusov, (Beta koronavirus), linija C. Genomi MERS-cov se filogenetsko ... MERS-CoV. Delci MERS-CoV, negativno obarvani, pod elektronskim mikroskopom. Virioni kažejo značilne palčice, ki štrlijo iz ... The full-genome sequence of MERS-CoV from dromedaries in this study is 99.9% similar to genomes of human clade B MERS-CoV.. ... "Ali se MERS-CoV prenaša od človeka do človeka?" najti odgovor "Za MERS-CoV je dokazano, da se širi med ljudmi, ki so v ...
SARS-CoV-2 er nært i slekt med SARS-CoV, viruset som valdar SARS hjå menneske.[110] Ein reknar med at det er zoonotisk. ... Saey, Tina Hesman (24 January 2020). «How the new coronavirus stacks up against SARS and MERS». Arkivert frå originalen 25 ... mars.[3] Pandemien kjem av eit nytt koronavirus, SARS-CoV-2.[4][5][6] Virussmitta kan føra til sjukdommen covid-19.[7] 20. mai ... SARS-CoV-2 (engelsk Severe acute respiratory syndrome coronavirus 2) er eit nytt virus som først blei isolert frå tre menneske ...
Some coronaviruses, e.g. SARS-CoV-1, MERS-CoV, and SARS-CoV-2 are activated by TMPRSS2 and can thus be inhibited by TMPRSS2 ... "SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming.[10] A TMPRSS2 ... SARS-CoV-2)". Molecules. 25 (10): 2271. doi:10.3390/molecules25102271. PMC 7287752. PMID 32408547.. ... "SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor". Cell. 181 (2): ...
She has led the country through Middle East respiratory syndrome (MERS), Influenza A virus subtype H7N9 (bird flu) and Dengue ... "Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore". JAMA. 323 (15): 1488. doi: ...
"Synthesizing data and models for the spread of MERS-CoV, 2013: Key role of index cases and hospital transmission". Epidemics. 9 ... 1910-11 Manchurian plague tuberculosis Norovirus monkeypox SARS-CoV-1 MERS Avian flu Sexually transmitted infections (STIs) or ... "Nosocomial amplification of MERS-coronavirus in South Korea, 2015". Transactions of the Royal Society of Tropical Medicine and ... sexually transmitted diseases (STDs): Syphilis, aka French pox SARS-CoV-2 Chowell, Gerardo; Blumberg, Seth; Simonsen, Lone; ...
MERS) is a viral respiratory illness. First reported in Saudi Arabia in 2012, it has since spread to the U.S. ... CDC Commentary: Be on the Lookout for MERS-CoVexternal icon. CDCs Dr. Susan Gerber provides an update on MERS, including when ... MERS in the U.S.. Information about the MERS situation in the U.S. and about the two imported cases confirmed in the U.S. in ... Photos of MERS-CoV and additional information for general public, media, healthcare professionals and laboratories… ...
MERS-CoV photos show how coronaviruses get their name - each virion is surrounded by a ... Human serum antibodies react with MERS-CoV-infected Vero cells, indicating the patient has been infected with MERS-CoV. ... An electron micrograph of a thin section of MERS-CoV, showing the spherical particles within the cytoplasm of an infected cell. ... MERS-CoV particles as seen by negative stain electron microscopy. Virions contain characteristic club-like projections ...
... * 1. Source: Al Arabiya News (published 11 May 2014) and The Washington Post, ... MERS). The current outbreak of MERS evolved significantly and protecting human infections and preventing a human pandemic is ... both MERS and SARS are coronaviruses. "Youre blocking the attachment of the antibody to the human cell," said Dr. Gregory ... MERS). According to the study recently published in the April 13 issue of the medical journal Vaccine, researchers from the ...
All Member States are reminded to promptly assess and notify WHO of any new case of infection with MERS-CoV, along with ... Recent travellers returning from the Middle East who develop SARI should be tested for MERS-CoV as advised in the current ... MERS-CoV) infection in Qatar.. The patient is a 23-year-old man who was identified as a close contact of a previously ... WHO has been informed of a total of 145 laboratory-confirmed cases of infection with MERS-CoV, including 62 deaths. ...
All Member States are reminded to promptly assess and notify WHO of any new case of infection with MERS-CoV, along with ... Middle East respiratory syndrome coronavirus (MERS-CoV) - update. 13 July 2013 - The Ministry of Health (MoH) in the United ... Recent travelers returning from the Middle East who develop SARI should be tested for MERS-CoV as advised in the current ... Clinicians are reminded that MERS-CoV infection should be considered even with atypical signs and symptoms, such as diarrhea, ...
The case is a 33 year-old male healthcare worker in Dubai who was in contact with the confirmed MERS-CoV case reported to WHO ... People at high risk of severe disease due to MERS-CoV should avoid close contact with animals when visiting farms or barn areas ... All Member States are reminded to promptly assess and notify WHO of any new case of infection with MERS-CoV, along with ... Recent travellers returning from the Middle East who develop SARI should be tested for MERS-CoV as advised in the current ...
MERS-CoV) from Saudi Arabia and the United Arab Emirates (UAE). ... People at high risk of severe disease due to MERS-CoV should ... All Member States are reminded to promptly assess and notify WHO of any new case of infection with MERS-CoV, along with ... It is not always possible to identify patients with MERS-CoV early because some have mild or unusual symptoms. For this reason ... Recent travellers returning from the Middle East who develop SARI should be tested for MERS-CoV as advised in the current ...
Virology Down Under MERS-CoV page Naming of MERS-CoV from Science (May 6, 2013). Genetic sequence of MERS-CoV from PHE ... MERS-CoV Images European Centre for Disease Prevention and Control (ECDC). MERS-CoV page Updated rapid risk assessment (Apr 25 ... MERS-CoV page. Key facts (Oct 4, 2013). Risk assessment (May 2, 2014). Treatment of MERS-CoV: Decision support tool (Jul 14, ... MERS-CoV page. Press release on first US case (May 2, 2014). Press release on clearing of contacts of first 2 US cases (Jun 17 ...
MERS is a corona virus, related to the common cold but more deadly. Find out what it is, what the risks are, how it spreads, ... The MERS coronavirus is related to the common cold.. MERS-CoV belongs to the coronavirus family, the same family of viruses ... Where the Middle East respiratory syndrome coronavirus (MERS-CoV, or MERS) comes from remains a mystery, but it probably ... Two cases of MERS-CoV have so far been confirmed in the United States. One was in Indiana and the other in Florida. Both ...
MERS-CoV) represents a novel human coronavirus that was initially reported from Saudi Arabia in 2012. ... Reservoir of MERS-CoV and Modes of Transmission. MERS-CoV is an example of a zoonotic virus transmitted from animals to humans ... Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Overview. *Middle East Respiratory Syndrome Coronavirus (MERS-CoV) ... Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Diagnosis. *Middle East Respiratory Syndrome Coronavirus (MERS-CoV) ...
This novel coronavirus differs from the previously identified coronaviruses such as the SARS coronavirus (SARS-CoV), which ... MERS-CoV) is a new beta virus strain of an animal coronavirus that was first identified in Saudi Arabia in September 2012. ... Outbreaks of MERS-CoV in the Middle East. Since the disease was first identified in Saudi Arabia in September 2012, ... New case of MERS-CoV identified in the United Kingdom news - 24 Aug 2018. ...
MERS-CoV) updates. Globally, as of 3 July 2015, 1363 cases including 487 deaths due to MERS-CoV have been reported to WHO. The ... MERS-CoV) Middle East respiratory syndrome coronavirus (MERS-CoV) updates ... News - MERS-CoV in the Republic of Korea: risk for importation remains, but low risk for spread within Europe 09-06-2015 ... News - MERS-CoV outbreak in Republic of Korea: a wake-up call in a highly mobile world 19-06-2015 ...
MERS-CoV) infection in a a 78-year-old male residing in Al Ain city. This is the fourth case of MERS-CoV reported in Al Ain in ... Two New #MERS #Coronavirus Cases Reported by #Saudi Arabia (@SaudiMOH, August 30 17), a post from the blog A TIMES MEMORY, ... HK, Suspected #MERS #Coronavirus case reported (CHP, August 21 17), a post from the blog A TIMES MEMORY, written by Giuseppe ... One New #MERS #Coronavirus Case reported by #Saudi Arabia (@SaudiMOH, August 22 2017), a post from the blog A TIMES MEMORY, ...
MERS) whose respiratory specimen tested negative for MERS Coronavirus (MERS-CoV), and hence called on the public to stay alert ... Early identification of MERS-CoV is important, but not all cases can be detected in a timely manner, especially mild or ... HCWs should arrange MERS-CoV testing for them. Patients lower respiratory tract specimens should be tested when possible and ... His nasopharyngeal aspirate tested negative for MERS-CoV upon preliminary laboratory testing by the CHPs Public Health ...
MERS-CoV) Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Background Middle East Respiratory Syndrome (MERS) or Middle ... Severe complications of MERS include pneumonia and kidney failure. Among confirmed MERS-CoV cases reported to date, the case ... The incubation period for MERS (the time between exposed to MERS-CoV and the start of symptoms) is usually about 5 or 6 days, ... Most people with MERS-CoV infection present with symptoms of fever, cough, and shortness of breath that may progress to severe ...
Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen. Jesper Pallesen, Nianshuang Wang, ... Cryo-EM structures of the stabilized MERS-CoV S protein in complex with a stem-directed neutralizing antibody provide a ... We also determined high-resolution structures of the trimeric MERS-CoV S ectodomain in complex with G4, a stem-directed ... Middle East respiratory syndrome coronavirus (MERS-CoV) is a lineage C betacoronavirus that since its emergence in 2012 has ...
Filipino female nurse PHs 1st MERS case; DOH tracking contacts. 11 who had close contact with PH nurse showing Mers-CoV ... Mers-CoVs incubation period is usually 5-6 days but can also range from 2-14 days and patients initially show mild symptoms ... OFW back in North Cotabato exhibiting Mers-CoV symptoms. By: Edwin Fernandez - @inquirerdotnet ... Jordan is among countries in or near the Arabian Peninsula, where cases of Mers-CoV had been reported since 2012. The others ...
MERS-CoV) causes acute respiratory illness thats sometimes fatal. Help protect yourself with good hygiene practices. ... Unlike influenza or the common cold, MERS-CoV doesnt seem to spread readily among people in communities. Instead, MERS-CoV has ... called MERS-CoV.. MERS-CoV was first reported in Saudi Arabia in 2012. Since then, its been reported in other countries in the ... Middle East respiratory syndrome coronavirus (MERS-CoV): Fact sheet N 401. http://www.who.int/mediacentre/factsheets/mers-cov/ ...
MERS situation update, June 2021. At the end of June 2021, a total of 2574 laboratory-confirmed cases of Middle East ... respiratory syndrome (MERS), including 886 associated deaths, were reported globally since 2012, with a case-fatality ratio ( ...
The MERS situation is serious and of great concern but doesnt constitute a global public health emergency, experts said ... MERS-CoV emerged last year in Jordan and Saudi Arabia, and the vast majority of cases have occurred in the Middle East. The ... The MERS-CoV (Middle East respiratory syndrome coronavirus) situation is "serious and of great concern" but doesnt rise to the ... At a press conference, Fukuda also said the WHO does not plan to recommend any travel restrictions over MERS-CoV, but it will ...
... nose and throat to MERS-CoV isolated from a patient. Each camel developed a mild upper respiratory tract infection consistent ... D Adney et al. Replication and Shedding of MERS-CoV in Upper Respiratory Tract of Inoculated Dromedary Camels. Emerging ... NIH study supports camels as primary source of MERS-CoV transmission NIH/National Institute of Allergy and Infectious Diseases ... As of July 23rd, the World Health Organization has reported a total of 837 human cases of MERS-CoV infection, including at ...
MERS-CoV) as a cause of severe respiratory disease highlights the need for effective approaches to CoV vaccine development. ... Accepted Manuscript: Evaluation of candidate vaccine approaches for MERS-CoV. Title: Evaluation of candidate vaccine approaches ... Immunization of rhesus macaques confers protection against MERS-CoV-induced radiographic pneumonia, as assessed using ... through sequencing of neutralization escape viruses and by constructing MERS-CoV S variants for serological assays. ...
Scientists reported today that they found strong evidence of the MERS-CoV (Middle East respiratory syndrome coronavirus) in a ... match between a bat sequence and a human MERS-CoV sequence. Another is that the Columbia lab had no MERS-CoV samples when the ... match for MERS-CoV. The sample was collected just a few kilometers from the home of one of the first MERS victims. ... MERS-CoV found in bat; hunt for other sources goes on. August 22, 2013. ScienceBlog.com ...
... July 24, 2014 ... It is not always possible to identify patients with MERS-CoV ... The patient was laboratory-confirmed with MERS-CoV on July 5, 2014 and died on the same day. The patient had no history of ... The patient did not have known contact with a previously reported MERS-CoV case. However, during her first hospitalisation, the ... Globally, 837 laboratory-confirmed cases of infection with MERS-CoV including at least 291 related deaths have officially been ...
MERS-CoV). This is the first case of MERS-CoV infection in Greece. ... This is the first case of MERS-CoV infection in Greece.. Individuals who had close contacts with the patient in the plane, the ... Health topics Communicable diseases Influenza Middle East respiratory syndrome coronavirus (MERS-CoV) update: Greece reports ... Middle East respiratory syndrome coronavirus (MERS-CoV) update: Greece reports first case. 20-04-2014. On 18 April 2014, the ...
SARS-CoV, and MERS-CoV infections. We searched PubMed,... ...operators and search terms covering SARS-CoV-2, SARS-CoV, OR MERS- ... except SARS-CoV and MERS-CoV, which, in addition to... ..., NL63, OC43, HKU1, SARS-CoV, and MERS-CoV. We used paired human... ... suggesting that MERS-CoV enters into the host cell... ...inhibit MERS-CoV... ...MERS-CoV... ... MERS-CoV) are two highly transmissible... ...coronaviruses that are related to SARS-CoV and MERS-CoV were discovered in bats ...
Find below the links to the Frequently Asked Questions on Middle East respiratory syndrome coronavirus (MERSCoV) updated last ...
  • CDC's Dr. Susan Gerber provides an update on MERS, including when to evaluate patients, how to collect appropriate specimens, and infection control. (cdc.gov)
  • 29 October 2013 - WHO has been informed of an additional laboratory-confirmed case of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in Qatar. (who.int)
  • Globally, from September 2012 to date, WHO has been informed of a total of 145 laboratory-confirmed cases of infection with MERS-CoV, including 62 deaths. (who.int)
  • Health care facilities that provide care for patients suspected or confirmed with MERS-CoV infection should take appropriate measures to decrease the risk of transmission of the virus to other patients, health care workers and visitors. (who.int)
  • All Member States are reminded to promptly assess and notify WHO of any new case of infection with MERS-CoV, along with information about potential exposures that may have resulted in infection and a description of the clinical course. (who.int)
  • 13 July 2013 - The Ministry of Health (MoH) in the United Arab Emirates (UAE) has notified WHO of a laboratory-confirmed case of infection with Middle East respiratory syndrome coronavirus (MERS-CoV) in the country. (who.int)
  • Globally, from September 2012 to date, WHO has been informed of a total of 82 laboratory-confirmed cases of infection with MERS-CoV, including 45 deaths. (who.int)
  • Clinicians are reminded that MERS-CoV infection should be considered even with atypical signs and symptoms, such as diarrhea, in patients who are immunocompromised. (who.int)
  • 14 April 2014 - WHO has been informed of an additional 16 laboratory-confirmed cases of infection with Middle East respiratory syndrome coronavirus (MERS-CoV) from Saudi Arabia and the United Arab Emirates (UAE). (who.int)
  • Infection prevention and control measures are critical to prevent the possible spread of MERS-CoV in health care facilities. (who.int)
  • Contact precautions and eye protection should be added when caring for probable or confirmed cases of MERS-CoV infection. (who.int)
  • The study reveals that healthcare workers from Saudi Arabia suffer from a high level of anxiety due to a higher risk of acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. (news-medical.net)
  • An international team of researchers has provided further evidence to confirm the immunogenicity and efficacy of a recombinant adenovirus vaccine currently being tested in phase 3 trials for its ability to protect against infection with severe acute respiratory coronavirus 2 (SARS-CoV-2) - the agent that causes coronavirus disease 2019 (COVID-19). (news-medical.net)
  • Accordingly, a first case of MERS-CoV infection in the US was identified on May 2, 2014, in a traveler who returned from the Kingdom of Saudi Arabia. (news-medical.net)
  • Since September 2012, WHO has been alerted under the International Health Regulations (IHR 2005) to sporadic cases and occasional clusters/outbreaks of infection with a novel coronavirus, (MERS-CoV). (who.int)
  • To determine the Variability in incubation periods for infection with Middle association between incubation period and severity of East respiratory syndrome coronavirus (MERS-CoV) has disease, we first estimated the difference in mean incu- been described ( 4 - 8 ). (cdc.gov)
  • 2 days during which infection was believed We estimated a mean incubation period of MERS-CoV in to have occurred, rather than exact dates of presumed infec- all 170 patients of 6.9 days (95% credibility interval [CrI] tion. (cdc.gov)
  • To date only two patients in the U.S. have ever tested positive for MERS-CoV infection-both in May 2014. (scdhec.gov)
  • Most people with MERS-CoV infection present with symptoms of fever, cough, and shortness of breath that may progress to severe acute respiratory illness. (scdhec.gov)
  • Healthcare providers are advised to be aware of patients who should be evaluated for MERS-CoV infection based on the current epidemiology of the disease, using clinical judgment and as information about modes of transmission of MERS-CoV and the clinical presentation continues to evolve. (scdhec.gov)
  • I've heard about the MERS-CoV infection. (mayoclinic.org)
  • As of July 23rd, the World Health Organization has reported a total of 837 human cases of MERS-CoV infection, including at least 291 deaths. (eurekalert.org)
  • On July 12, 2014, the National IHR Focal Point of the Islamic Republic of Iran reported to the World Health Organization (WHO) an additional laboratory-confirmed case of infection with Middle East respiratory syndrome coronavirus (MERS-CoV). (infectioncontroltoday.com)
  • Globally, 837 laboratory-confirmed cases of infection with MERS-CoV including at least 291 related deaths have officially been reported to WHO. (infectioncontroltoday.com)
  • Until more is understood about MERS-CoV, people with diabetes, renal failure, chronic lung disease, and immunocompromised persons are considered to be at high risk of severe disease from MERS‐CoV infection. (infectioncontroltoday.com)
  • Here, we tested the efficacy of the broad-acting antiviral remdesivir in the rhesus macaque model of MERS-CoV infection. (pnas.org)
  • Here, we tested the efficacy of prophylactic and therapeutic remdesivir treatment in a nonhuman primate model of MERS-CoV infection, the rhesus macaque. (pnas.org)
  • The engagement of the MERS-CoV spike protein with CD26 mediates viral attachment to host cells and virus-cell fusion, thereby initiating infection. (nih.gov)
  • The rhesus macaque is the only known model organism for MERS-CoV infection, developing an acute localized to widespread pneumonia with transient clinical disease that recapitulates mild to moderate human MERS-CoV cases. (nih.gov)
  • As of 3 June 2015, 1179 laboratory-confirmed cases of human infection with Middle East respiratory syndrome coronavirus (MERS-CoV) have been reported to WHO since 2012. (emergencydispatch.org)
  • IMPORTANT: Alert the crew of any vehicle dispatched to a patient who is symptomatic of MERS-CoV to ensure that necessary infection control precautions and policies are followed. (emergencydispatch.org)
  • Wu J , Yi L , Zou L , Zhong H , Liang L , Song T , Song Y , Su J , Ke C . Imported case of MERS-CoV infection identified in China, May 2015: detection and lesson learned. (eurosurveillance.org)
  • At the end of May 2015, an imported case of Middle East respiratory syndrome coronavirus (MERS-CoV) infection was confirmed in China. (eurosurveillance.org)
  • Capitalizing on the wealth of public opinion data contained in posts on Weibo, this study used Weibo as a measure of the Chinese people's reactions to two different outbreaks: the 2012 Middle East Respiratory Syndrome Coronavirus (MERS-CoV) outbreak, and the 2013 outbreak of human infection of avian influenza A(H7N9) in China. (biomedsearch.com)
  • Disclosing the list of hospitals exposed to MERS-CoV was critical to the prevention of further infection. (mdpi.com)
  • Multiple studies suggest that dromedary camels are a source for human MERS-CoV infection. (unboundmedicine.com)
  • Israel's geographic location places Israel at risk for MERS-CoV infection. (unboundmedicine.com)
  • To date, MERS-CoV-related illness has not been reported and the burden of MERS-CoV infection in the Israeli population is unknown. (unboundmedicine.com)
  • Footnote 3 The current pattern of infection appears to be the result of repeated introduction of MERS-CoV from camels to humans, with limited secondary human-to-human transmission. (canada.ca)
  • The clinical manifestation of MERS-CoV infection ranges from asymptomatic or mild respiratory symptoms to severe acute respiratory disease and death. (nccid.ca)
  • Camels are likely to be a major reservoir host for MERS-CoV and an animal source of MERS infection in humans. (nccid.ca)
  • Although recent studies point to the role of camels as a primary source of MERS-CoV infection in humans through direct or indirect contact with infected camels or camel-related products (e.g. raw camel milk), the exact role of camels in transmission of the virus and the exact route(s) of transmission are unknown. (nccid.ca)
  • All experts thought that MERS-CoV-infected dromedaries and asymptomatic humans play the most important role in infection of humans, with bats and other species presenting a possible, but yet undefined, risk. (frontiersin.org)
  • These results show that AdC68-S can induce protective immune responses in mice and represent a promising candidate for further development against MERS-CoV infection in both dromedaries and humans. (unboundmedicine.com)
  • The first case of MERS Co-V infection in the United States, identified in a traveler, was reported to CDC by the Indiana State Department of Health (ISDH) on May 1, 2014, and confirmed by CDC on May 2. (montcopa.org)
  • Providers should notify the infection preventionist and local health department immediately if they are evaluating a person meeting the case definition for MERS-CoV. (wvoems.org)
  • Here, we analyzed the antiviral activities of resveratrol, a natural compound found in grape seeds and skin and in red wine, against MERS-CoV infection. (biomedcentral.com)
  • Resveratrol significantly inhibited MERS-CoV infection and prolonged cellular survival after virus infection. (biomedcentral.com)
  • We perceive that resveratrol can be a potential antiviral agent against MERS-CoV infection in the near future. (biomedcentral.com)
  • As a result, we tested whether a natural stilbene derivative, resveratrol ( trans -3, 5, 4′-trihydroxystilbene) inhibits the MERS-CoV infection in this study. (biomedcentral.com)
  • However, it remains unknown whether resveratrol can inhibit MERS-CoV infection. (biomedcentral.com)
  • MERS-CoV (HCoV-EMC/2012) was diluted to multiplicity of infection (M.O.I.) 0.1 with 2% FBS/DMEM and replaced the culture media in plates. (biomedcentral.com)
  • The source of MERS-CoV infection and the mode of transmission have not been identified, but the continued detection of cases in the Middle East indicates that there is an ongoing source of infection in the region. (flutrackers.com)
  • The team will be comprised of experts in epidemiology, virology, clinical management, infection prevention and control, as well as public health officers who have previously handled other MERS-CoV outbreaks in the Middle East. (healthcanal.com)
  • More detailed information on surveillance guidelines, including recommendations for surveillance objectives, activities, laboratory testing, and reporting of results, are described in the National Surveillance Guidelines for Human Infection with Middle East Respiratory Syndrome Coronavirus (MERS-CoV) . (canada.ca)
  • Note: Limited data suggests that MERS-CoV can present as a co-infection with other viral pathogens. (canada.ca)
  • A person with laboratory confirmation of MERS-CoV infection at Canada's National Microbiology Laboratory (NML). (canada.ca)
  • Rather, MERS-CoV infection is similar to Severe Acute Respiratory Syndrome coronavirus (SARS-CoV), as disease is associated with acute respiratory distress syndrome. (pubmedcentralcanada.ca)
  • In addition, MERS-CoV infection can result in kidney failure, ultimately leading to death [ 1 - 3 ]. (pubmedcentralcanada.ca)
  • The antibody responses were associated with blocking viral replication and upper and lower respiratory tract protection against MERS-CoV infection in rabbits. (eur.nl)
  • Using MERSpv-St16, we demonstrated the inability of rat DPP4 to serve as a functional receptor for MERS-CoV, suggesting that rats are not susceptible to MERS-CoV infection. (deepdyve.com)
  • Confirmed case - a person with laboratory confirmed infection with MERS-CoV. (vic.gov.au)
  • To search for evidence of autochthonous MERS-CoV infection in humans, we tested archived serum from livestock handlers in Kenya for MERS-CoV antibodies. (cdc.gov)
  • Between 18 and 28 August 2015, the National IHR Focal Point for the Kingdom of Saudi Arabia notified World Health Organization (WHO) of 42 additional cases of Middle East Respiratory Syndrome coronavirus (MERS-CoV) infection [1, 2], including 7 deaths. (travelhealthpro.org.uk)
  • The risk of infection with MERS-CoV to UK residents in the UK remains very low [4]. (travelhealthpro.org.uk)
  • Clinicians are reminded that MERS-CoV infection should be considered even with atypical signs and symptoms, especially in individuals with diabetes, kidney failure, chronic lung disease and immune compromised persons. (travelhealthpro.org.uk)
  • The Middle East respiratory syndrome (or MERS) is an infection caused by MERS-Coronavirus or MERS-CoV. (cresa.cat)
  • We inoculated 3 adult camels with a human isolate of MERS-CoV and a transient, primarily upper respiratory tract infection developed in each of the 3 animals. (blogspot.com)
  • Clinical signs of the MERS-CoV infection were benign, but each of the camels shed large quantities of virus from the upper respiratory tract. (blogspot.com)
  • Possible infection via consumption of camel milk or camel meat was not investigated, and remains an open question (see Eurosurveillance: MERS-CoV Antibodies & RNA In Camel's Milk - Qatar ). (blogspot.com)
  • Serologic studies in camels in the field have reported MERS-CoV neutralizing titers as high as 5,120 ( 14 , 16 ), potentially indicative of repeated exposure and re-infection. (blogspot.com)
  • Staff who are coordinating homecare and isolation or quarantine of people who are being evaluated for or are confirmed to have MERS-CoV infection can use this guidance to assess the suitability of the home care setting and provide guidance to the patient and household members. (hhs.gov)
  • The size of the population infected with MERS-CoV showed a gradual increase to June 2013, followed by a decline, possibly due to increased surveillance and infection control measures combined with a basic reproduction number (R0) for the virus that is less than 1. (ed.ac.uk)
  • Owing to improved infection prevention and control practices in hospitals, the number of hospital-acquired cases of MERS has dropped significantly since 2015. (blogspot.com)
  • A more detailed understanding of the kinetics of infection of MERS-CoV is needed in order to optimise the use of existing assays. (bmj.com)
  • 1 As of 30 October 2018, the WHO has been notified of more than 2254 laboratory-confirmed cases of MERS-CoV infection from 27 countries, including 800 deaths ( figures 1 and 2 ). (bmj.com)
  • As of 13 November 2015, 1618 laboratory-confirmed human cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection, including 579 deaths, had been reported to the World Health Organization. (umaryland.edu)
  • Administration of single doses of SAB-301 12 hours before or 24 and 48 hours after MERS-CoV infection (Erasmus Medical Center 2012 strain) of Ad5-hDPP4 receptor-transduced mice rapidly resulted in viral lung titers near or below the limit of detection. (umaryland.edu)
  • Tc bovines, combined with the ability to quickly produce Tc hIgG and develop in vitro assays and animal model(s), potentially offer a platform to rapidly produce a therapeutic to prevent and/or treat MERSCoV infection and/or other emerging infectious diseases. (umaryland.edu)
  • Feasibility of Using Convalescent Plasma Immunotherapy for MERS-CoV Infection, Saudi Arabia. (umaryland.edu)
  • A truncated receptor-binding domain of MERS-CoV spike protein potently inhibits MERS-CoV infection and induces strong neutralizing antibody responses: implication for developing therapeutics and vaccines. (umaryland.edu)
  • The MERS-CoV and respiratory viruses detection results at points of entry in China from 2013 to 2015 indicated that there were no MERS-CoV infection but a 5.7% positive influenza viruses in returning Chinese pilgrims. (biomedcentral.com)
  • Most cases of MERS-CoV infection were reported from the Kingdom of Saudi Arabia. (biomedcentral.com)
  • The age group of those aged 50-59 years continues to be the group at highest risk for 12 countries reported MERS since April 2012 acquiring infection as primary cases. (who.int)
  • 2 countries reported MERS since April 2012 risk for acquiring infection as primary cases. (who.int)
  • [14] However, it was later discovered that neutralization of ACE2 by recombinant antibodies does not prevent MERS-CoV infection. (wordpress.com)
  • If highly suspicious, repeat sample every 4 days until negative till 14 days Also pls request for influenza PCR/IF /sputum culture & sensitivity MERS-CoV Infection: Management Of Close Contacts To A Probable / Confirmed Case Asymptomatic ● Hand-out / pamphlet about MERS-CoV ● ● ● Mild symptoms ● ● Home Assessment Tool 14 days surveillance (i.e. from the date of last exposure ● ● no restriction of movement ● HOME SURVEILLANCE RESTRICTION on his / her daily movement. (studylib.net)
  • MERS-CoV is a new novel coronavirus that caused severe acute respiratory infection (SARI) first identified in Saudi Arabia in September 2012. (medicinenet.com)
  • Those who handle camels are at higher risk of MERS-CoV infection than people who do not have regular close contacts with camels. (medicinenet.com)
  • MERS-CoV infection should be suspected in travelers from the Arabian Peninsula or neighboring countries with symptoms compatible with MERS-CoV occurring within 10 days of traveling. (medicinenet.com)
  • MERS-CoV is a coronavirus that can cause severe acute respiratory infection in humans. (medicinenet.com)
  • Recently, it was reported that four doctors from a main hospital in the western city of Saudi Arabia have resigned after they refused to treat patients with MERS-CoV due to the fear of infection and some facilities have been temporarily shut down last month after numerous health staffs got infected with the virus (Times of Oman 2014). (rnspeak.com)
  • The Centers for Disease Control and Prevention defined MERS-CoV or Middle East Respiratory Syndrome CoronaVirus as a form of viral infection affecting the respiratory system (CDC 2014a). (rnspeak.com)
  • Middle East respiratory syndrome coronavirus (MERS-CoV) represents a novel human coronavirus that was initially reported from Saudi Arabia in 2012. (news-medical.net)
  • Since the disease was first identified in Saudi Arabia in September 2012, approximately 2 000 MERS-CoV cases have been detected in over 20 countries. (europa.eu)
  • MERS-CoV was first reported in Saudi Arabia in 2012. (mayoclinic.org)
  • The WHO announcement came hours after Saudi Arabia reported two more confirmed MERS-CoV cases, both of them mild. (umn.edu)
  • MERS-CoV emerged last year in Jordan and Saudi Arabia, and the vast majority of cases have occurred in the Middle East. (umn.edu)
  • Scientists reported today that they found strong evidence of the MERS-CoV (Middle East respiratory syndrome coronavirus) in a bat from Saudi Arabia, suggesting that, as suspected, bats are the virus's natural reservoir. (scienceblog.com)
  • During the October trip, the team interviewed the family of an index MERS patient in Bisha, Saudi Arabia, and collected samples from bats in an abandoned date palm orchard less than 12 kilometers from his home and also from a site near the hardware store where he worked, according to the report. (scienceblog.com)
  • Additionally, Saudi Arabia reported three deaths among previously reported MERS-CoV cases. (infectioncontroltoday.com)
  • In March, 7 laboratory-confirmed cases of MERS were reported in Saudi Arabia including 1 associated death. (who.int)
  • MERS-CoV was discovered in Saudi Arabia in 2012, and, as of June 9 , 2015 , has caused severe respiratory illness in 1218 laboratory-confirmed human cases, of which at least 449 resulted in death. (canada.ca)
  • MERS-CoV is circulating in the Arabian Peninsula, primarily in Saudi Arabia. (canada.ca)
  • The outbreak in the Republic of Korea (beginning May 20, 2015) is the largest outbreak outside of the Middle East, resulting from a single exported case with travel history in the Middle East (Saudi Arabia, Qatar, United Arab Emirates (UAE) and Bahrain) and subsequent human-to-human transmission to close contacts and health care workers providing care for patients before MERS was suspected or diagnosed. (nccid.ca)
  • Nearly 4 years after the first report of the emergence of Middle-East respiratory syndrome Coronavirus (MERS-CoV) in humans and more than 1800 human cases later ( 1 ), mainly in Saudi Arabia (~75% of cases and almost all of the primary cases), the ecology of MERS-CoV and its epidemiology remain poorly understood ( 2 ). (frontiersin.org)
  • This strain of coronavirus that causes MERS was first identified in 2012 in Saudi Arabia. (montcopa.org)
  • Only 28% of Australian Hajj pilgrims were aware of MERS-CoV in Saudi Arabia. (ovid.com)
  • As of 4 October 2013, (MERS-CoV) has been identified in 136 patients in or from Saudi Arabia, Qatar, UK, France, Italy, Germany, Tunisia, Jordan and the United Arab Emirates (UAE) associated in most cases with a severe acute pneumonia. (vic.gov.au)
  • Two health experts from the Research Institute for Tropical Medicine (RITM), meanwhile, have been sent to the United Arab Emirates and Saudi Arabia earlier this week to check on the status of OFWs amid cases of MERS-CoV there. (typepad.com)
  • ABSTRACT The Middle East respiratory syndrome coronavirus (MERS-CoV) was first documented in the Kingdom of Saudi Arabia (KSA) in 2012 and, to date, has been identified in 180 cases with 43% mortality. (ed.ac.uk)
  • At the same time, however, we've not seen a detailed WHO DON report from Saudi Arabia ( with case line listing ) since January of this year, easily the longest lull in reporting since the MERS virus emerged in 2012. (blogspot.com)
  • Two weeks ago, in WHO: UAE MERS-CoV Case & IHR Concerns, an updated line listing of cases was published, but it contained no new entries from Saudi Arabia since the middle of January. (blogspot.com)
  • All of which means that - for now, at least - we are pretty much dependent upon the abbreviated WHO EMRO monthly MERS summary reports to keep track MERS activity in Saudi Arabia. (blogspot.com)
  • During the month of May, a total of 12 laboratory-confirmed cases of MERS were reported globally: 11 cases in Saudi Arabia including 1 associated death and one case reported in United Arab Emirates. (blogspot.com)
  • The Middle East respiratory syndrome-coronavirus (MERS-CoV) is an emerging virus associated with severe respiratory illness, first detected in 2012 in Saudi Arabia. (bmj.com)
  • United Arab Emirates deaths reported from MERS since reported in Saudi Arabia including two associated deaths. (who.int)
  • Di Saudi Arabia telah ditemukan antibodi terhadap MERS - CoV yang cukup tinggi pada unta, virus diisolasi dari nasal dan kotoran unta. (wordpress.com)
  • An isolate of the MERS-CoV from the first patient identified was found in an Egyptian tomb bat near the victim's home in Saudi Arabia. (wikipedia.org)
  • The current outbreak of MERS evolved significantly and protecting human infections and preventing a human pandemic is currently part of the global agenda. (slideshare.net)
  • MERS-CoV is different from the coronavirus that caused the 2003 outbreak of SARS , but both viruses are similar to the types of coronavirus found in bats. (medicalnewstoday.com)
  • The MERS outbreak, which began in 2012, continues throughout the Middle East. (eurekalert.org)
  • Since May 2015, the Republic of Korea has been investigating an outbreak of MERS-CoV. (wisconsin.gov)
  • It is the largest known outbreak of MERS-CoV outside the Arabian Peninsula. (wisconsin.gov)
  • Although many coronaviruses cause only mild cases of the common cold, emerging species such as SARS-CoV-2 and SARS-CoV (the cause of the 2003 SARS outbreak) pose a serious risk to global health and security. (eurekalert.org)
  • This is the largest outbreak of MERS-CoV outside the Middle East. (emergencydispatch.org)
  • RESULTS: The results show that the Chinese people reacted significantly to both outbreaks online, where their social media reaction was two orders of magnitude stronger to the H7N9 influenza outbreak that happened in China than the MERS-CoV outbreak that was far away from China. (biomedsearch.com)
  • Noh J-W, Yoo K-B, Kwon YD, Hong JH, Lee Y, Park K. Effect of Information Disclosure Policy on Control of Infectious Disease: MERS-CoV Outbreak in South Korea. (mdpi.com)
  • As of June 24, the World Health Organization is reporting 179 cases of MERS-CoV, including 27 deaths from a large outbreak in Korea and China. (wvoems.org)
  • Human infections with MERS-CoV typically occur in countries located in the Middle East, but in May 2015 an outbreak was reported in South Korea, in which three super-spreaders were found to be responsible for the majority of infections, as well as evidence of tertiary human-to-human transmission [ 5 ]. (pubmedcentralcanada.ca)
  • Of the 42 cases reported, 36 cases are associated with a MERS-CoV outbreak currently occurring in a hospital in Riyadh city [1, 2]. (travelhealthpro.org.uk)
  • One of the cases is associated with a smaller MERS-CoV outbreak occurring at another hospital in Riyadh city [1]. (travelhealthpro.org.uk)
  • The risk of a MERS-CoV outbreak in Cambodia remains low as sustained human-to-human transmission of the virus has not been reported. (gov.kh)
  • In this review we identified sources for molecular and serological diagnostic tests used in MERS-CoV detection, case management and outbreak investigations, as well as surveillance for humans and animals (camels), and summarised the performance of currently available tests, diagnostic needs, and associated challenges for diagnostic test development and implementation. (bmj.com)
  • A defined set of Target Product Profiles for diagnostic technologies will be developed by WHO to address these gaps in MERS-CoV outbreak management. (bmj.com)
  • In this outbreak, transmission of MERS-CoV has been strongly associated with health care settings. (studylib.net)
  • Up to date, MERS disease mortality surged to 40% since its outbreak in 2012 and is considered deadlier but less transmissible compare to SARS or Severe Acute Respiratory Syndrome (Times of Oman 2014). (rnspeak.com)
  • MERS-CoV has so far been shown to infect humans, camels, and bats. (medicalnewstoday.com)
  • Correspondingly, published research indicates that the natural reservoirs of MERS-CoV are camels. (news-medical.net)
  • During August 2013 there was a report in the Lancet (Infectious Diseases) on the finding of specific antibodies against MERS-CoV in 100% of Oman and 14% of Spanish camels. (news-medical.net)
  • Initial enquiries by the CHP revealed that the patient had no contact with animals (including camels) and MERS patients. (gov.hk)
  • National Institutes of Health (NIH) and Colorado State University (CSU) scientists have provided experimental evidence supporting dromedary camels as the primary reservoir, or carrier, of Middle East respiratory syndrome coronavirus (MERS-CoV). (eurekalert.org)
  • The study, designed by scientists from CSU and NIH's National Institute of Allergy and Infectious Diseases, involved three healthy camels exposed through the eyes, nose and throat to MERS-CoV isolated from a patient. (eurekalert.org)
  • Replication and Shedding of MERS-CoV in Upper Respiratory Tract of Inoculated Dromedary Camels. (eurekalert.org)
  • Today's report comes less than 2 weeks after the report that a number of camels in Oman and the Canary Islands tested positive for antibodies to MERS-CoV, suggesting past exposure to the virus. (scienceblog.com)
  • Dromedary camels were identified as the reservoir for MERS-CoV. (nih.gov)
  • MERS-CoV appears to have been circulating in dromedary camels over 20 years. (nih.gov)
  • MERS-CoV replicates predominantly in the upper respiratory tract of dromedary camels. (nih.gov)
  • MERS-CoV-specific antibodies have been detected in the serum of dromedary camels across Northern Africa and across the Arabian Peninsula. (unboundmedicine.com)
  • The seroprevalence of MERS-CoV-specific antibodies in Israeli dromedary camels is unknown. (unboundmedicine.com)
  • The objective of this study was to determine the prevalence of MERS-CoV seropositivity in dromedary camels in Israel. (unboundmedicine.com)
  • The prevalence of MERS-CoV antibodies in Israeli camels was examined in 71 camel sera collected from four farms across Israel by MERS-CoV-specific microneutralization (Mnt) assay and confirmed by MERS-CoV-specific immunofluorescence assay (IFA). (unboundmedicine.com)
  • These findings extend the known range of MERS-CoV circulation in Middle Eastern camels. (unboundmedicine.com)
  • The high rate of MERS-CoV-specific antibody seropositivity in dromedary camels in the absence of any reported human MERS cases suggests that there is still much to be learned about the dynamics of camel-to-human transmission of MERS-CoV. (unboundmedicine.com)
  • An increasing incidence of MERS-CoV from March-April suggests a seasonal pattern which might be related to the weaning of young camels from their mothers in the spring of each year or corresponding to calving season and an increased pool of susceptible camels shedding virus in early spring. (nccid.ca)
  • Nearly 4 years after the first report of the emergence of Middle-East respiratory syndrome Coronavirus (MERS-CoV) and nearly 1800 human cases later, the ecology of MERS-CoV, its epidemiology, and more than risk factors of MERS-CoV transmission between camels are poorly understood. (frontiersin.org)
  • Fourteen experts with diverse and extensive experience in MERS-CoV relevant fields were enrolled and completed an online questionnaire that examined pathways based on several scenarios, e.g., camels-camels, camels-human, bats/other species to camels/humans, and the role of diverse biological substances (milk, urine, etc.) and potential fomites. (frontiersin.org)
  • Results indicated that camel-exposed cases occur under a narrower suite of environmental conditions than non-camel-exposed cases, suggesting perhaps a key role for camels in the transmission of the disease, and perhaps a narrower area of risk for 'primary,' camel-derived cases of MERS. (ku.edu)
  • Through a prospective cohort study the relationship between travellers' awareness of MERS-CoV, and compliance with preventive measures and exposure to camels was evaluated among Australian Hajj pilgrims who attended Hajj in 2015. (ovid.com)
  • MERS-CoV: dromedary camels clearly established as a host, dating at least to early 1990s. (hopkinsguides.com)
  • The case for camels being a likely route of MERS-CoV to humans has become a bit stronger with yesterday's publication of an EID journal study showing that camels intentionally inoculated with the human MERS strain shed copious amounts of the virus via nasal discharge for at least a week. (blogspot.com)
  • This isn't the first time camels have been implicated as an intermediate host ( bats are still eyed as the likely primary reservoir of the MERS virus ), but this study does show a plausible route of both camel-to-camel and camel-to-human transmission. (blogspot.com)
  • A couple of weeks ago, the KSA MOH Reiterated Camel Warnings On MERS , urging breeders and owners to limit their contact with camels, and to use PPEs ( masks, gloves, protective clothing ) when in close contact with their animals. (blogspot.com)
  • Today's study not only shows that infected camels can shed massive amounts of the MERS coronavirus from their nasal discharges, that they can do so without showing other signs of serious illness. (blogspot.com)
  • Epidemiologic investigations identified dromedary camels as the likely source of zoonotic transmission of Middle East respiratory syndrome coronavirus (MERS-CoV). (blogspot.com)
  • Here we provide experimental support for camels as a reservoir for MERS-CoV. (blogspot.com)
  • This is actually some pretty impressive work, and helps fill in some major gaps in our knowledge of the ecology of the MERS virus among camels. (blogspot.com)
  • The large quantities of MERS-CoV shed in nasal secretions by each of the 3 camels suggest that camel-to-camel and camel-to-human transmission may occur readily through direct contact and large droplet, or possibly fomite transmission. (blogspot.com)
  • Histopathologic examination revealed that the URT, specifically the respiratory epithelium in the nasal turbinates, is the predominant site of MERS-CoV replication in camels. (blogspot.com)
  • As such, this paper explores the geographic and environmental circumstances under which MERS-CoV has been transmitted from camels to humans, and where those high-risk circumstances are manifested (i.e., developing a risk map of transmission probabilities). (biomedcentral.com)
  • IF NO ( lungs clear, xray normal, clinically comfortable on room air) = Not PUI MERCOV STEP 5 ● Assess Severity IF 1 YES IS CONSIDERED MODERATE TO SEVERE ILLNESS AND NEEDS ADMISSION IF ALL NO, MILD ILLNESS Clinical Assessment of Severity STEP 6 ● ● IF Severity Mild, Not considered PUI MERSCOV However if severity Mild, with contact with camels or confirmed cases of MERCOV, To admit ward as PUI MERCOV. (studylib.net)
  • It has been detected in camels, and several cases of MERS-CoV in those who handle camels have been reported. (medicinenet.com)
  • Researchers suggest the MERS virus originated in animals (camels) and, like other viruses, mutated to be able to infect humans. (medicinenet.com)
  • MERS-CoV has been detected in camels in several countries but not in other livestock. (medicinenet.com)
  • Serum obtained from dromedary camels immunized with a MVA vaccine expressing the spike protein and challenged with MERS-CoV. (european-virus-archive.com)
  • The biotechnology firm Novavax (Gaithersburg, USA) and researchers of the University of Maryland School of Medicine have reportedly created an experimental vaccine against the Middle East Respiratory Syndrome (MERS). (slideshare.net)
  • There is currently no vaccine or cure for MERS-CoV, and so far it has been fatal in around 36 percent of cases. (medicalnewstoday.com)
  • A new study reports the preclinical testing of a recombinant MVA (rMVA) candidate vaccine against SARS-CoV-2, the agent that is causing the current COVID-19 pandemic. (news-medical.net)
  • There's currently no vaccine to prevent MERS-CoV. (mayoclinic.org)
  • The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) as a cause of severe respiratory disease highlights the need for effective approaches to CoV vaccine development. (osti.gov)
  • Immunization of rhesus macaques confers protection against MERS-CoV-induced radiographic pneumonia, as assessed using computerized tomography, supporting this strategy as a promising approach for MERS-CoV vaccine development. (osti.gov)
  • This is a clinical trial in which healthy volunteers will be administered an experimental MERS vaccine. (clinicaltrials.gov)
  • The vaccine ChAdOx1 MERS will be administered alone both as a single administration and with a homologous prime-booster. (clinicaltrials.gov)
  • The ChAdOx1 MERS vaccine consists of the replication-deficient simian adenovirus vector ChAdOx1, containing the MERS Spike protein antigen. (clinicaltrials.gov)
  • There is no vaccine available for MERS-CoV . (www.gov.uk)
  • The MERS-CoV envelope spike protein serves as a crucial target for neutralizing antibodies and vaccine development, as it plays a critical role in mediating viral entry through interactions with the cellular receptor, dipeptidyl peptidase 4 (DPP4). (unboundmedicine.com)
  • Up to date, there is no approved or licensed vaccine or antiviral medicines can be used to treat MERS-CoV-infected patients. (biomedcentral.com)
  • There is still no effective anti-MERS medicine or vaccine commercially available in the market. (biomedcentral.com)
  • This discovery not only provides more alternative vaccine development platforms for MERS-CoV vaccine development, but also provides a theoretical basis for our future selection of vaccine vector platforms for other specific pathogens. (medworm.com)
  • These data demonstrate that MERS-CoV VLPs have excellent immunogenicity in rhesus macaques, and represent a promising vaccine candidate. (pubmedcentralcanada.ca)
  • As such, there is an urgent need for the development of an efficacious vaccine against MERS-CoV. (pubmedcentralcanada.ca)
  • There are no reports of inactivated MERS-CoV being tested as a vaccine, but an inactivated SARS-CoV vaccine appears to have little effect in mice and domestic ferrets [ 6 - 8 ]. (pubmedcentralcanada.ca)
  • This arrayed multivalent presentation of the viral RBD using the antigen-SpyTag/LS-SpyCatcher is a promising MERS-CoV vaccine candidate and this platform may be applied for the rapid development of vaccines against other emerging viruses such as SARS-CoV-2. (eur.nl)
  • Negative stain electron microscopy shows a MERS-CoV particle with club-shaped surface projections surrounding the periphery of the particle, a characteristic feature of coronaviruses. (cdc.gov)
  • both MERS and SARS are coronaviruses. (slideshare.net)
  • As coronaviruses tend to mutate, there are concerns that MERS could become a pandemic. (medicalnewstoday.com)
  • Human coronaviruses were first classified in the mid-1960s, and six of them are known to affect humans, including severe acute respiratory syndrome (SARS) and MERS. (medicalnewstoday.com)
  • Coronaviruses typically infect a single species or species that are closely related, but SARS-CoV infects both humans and animals. (medicalnewstoday.com)
  • In an exciting, state-of-the-art study currently available on the medRxiv* preprint server, US researchers created a multi-coronavirus protein microarray containing full-length proteins, peptide libraries, and overlapping protein fragments from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well as four other human coronaviruses. (news-medical.net)
  • If it becomes endemic -- circulating in the general population -- and most people are exposed in childhood, SARS-CoV-2 may join the ranks of mild cold-causing coronaviruses that currently circulate in humans, according to a model developed by Emory and Penn State scientists. (news-medical.net)
  • Other known coronaviruses are SARS and MERS-CoV. (who.int)
  • Middle East Respiratory Syndrome (MERS) or Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is an illness caused by coronaviruses, a large family of viruses causing diseases ranging in severity from the common cold to Severe Acute Respiratory Syndrome (SARS). (scdhec.gov)
  • Currently available diagnostic tests for seasonal coronaviruses are not suitable for detecting MERS CoV. (wisconsin.gov)
  • A team of scientists has engineered antiviral compounds that can kill several types of coronaviruses, including SARS-CoV-2, the virus that causes COVID-19. (eurekalert.org)
  • Genetic sequence data indicate that MERS-CoV is a beta-coronavirus similar to bat coronaviruses, but distinct from SARS-CoV. (canada.ca)
  • Study design: Both sensitivity and specificity were assessed using 12 samples containing different viral loads of MERS-CoV or common coronaviruses (OC43, 229E, NL63, HKU1). (eur.nl)
  • His second postdoctoral position was at the University of Maryland School of Medicine where he worked on many aspects of highly pathogenic human coronaviruses SARS-CoV and MERS-CoV. (lshtm.ac.uk)
  • Middle East respiratory syndrome coronavirus (MERS-CoV) is a betacoronavirus infecting humans, but MERS-CoV disease is markedly different from other human coronaviruses including HCoV-HKU1, HCoV-NL63, HCoV-OC43 and HCoV-229E, which are known to cause mild respiratory infections. (pubmedcentralcanada.ca)
  • As it relates to countries with the ongoing MERS-CoV community cases and hospital acquired infections, there will be a huge challenge for HCWs to deal with both coronaviruses, especially with the lack of standardized and approved point of care testing. (atlantis-press.com)
  • MERS-CoV has never previously been detected in humans or animals but appears most closely related to coronaviruses previously found in bats. (vic.gov.au)
  • The recently reported Middle East respiratory syndrome coronavirus (MERS-CoV) is phylogenetically closely related to the bat coronaviruses (BatCoVs) HKU4 and HKU5. (semanticscholar.org)
  • Introduction: Coronaviruses (CoV) are a diverse group of viruses which has been described in the literature since 1960, SARS, MERS and the most recent SARS-CoV-2. (eurekaselect.com)
  • Like the SARS virus, MERS-CoV is most similar to coronaviruses found in bats. (medicinenet.com)
  • The new virus, Wuhan virus (also termed 2019-nCoV ), is an RNA virus related to both MERS and SARS coronaviruses. (medicinenet.com)
  • However, the MERS-CoV virus is different than other coronaviruses, including SARS-CoV, and had never been identified before 2012. (medicinenet.com)
  • Human serum antibodies react with MERS-CoV-infected Vero cells, indicating the patient has been infected with MERS-CoV. (cdc.gov)
  • Although this study cannot rule out potential antibody cross-reactivity by IFA, the presence of bovine coronavirus-specific antibodies do not appear to impact detection of MERS-CoV antibodies by Mnt. (unboundmedicine.com)
  • MERS-CoV neutralizing antibodies were detectable in 51 (71.8%) camel sera, and no association was observed between the presence of neutralizing antibodies and camel age or gender. (unboundmedicine.com)
  • Rhesus macaques inoculated with MERS-CoV VLPs and Alum adjuvant induced virus-neutralizing antibodies titers up to 1:40 and induced specific IgG antibodies against the receptor binding domain (RBD), with endpoint titers reaching 1:1,280. (pubmedcentralcanada.ca)
  • Convalescent serum with high neutralizing antibody titer against MERS-CoV may be of use as well as any specific monoclonal antibodies (not available). (hopkinsguides.com)
  • Two experimental MERS-CoV vaccines were used to vaccinate two groups of transchromosomic (Tc) bovines that were genetically modified to produce large quantities of fully human polyclonal immunoglobulin G (IgG) antibodies. (umaryland.edu)
  • Two cases of MERS-CoV have so far been confirmed in the United States. (medicalnewstoday.com)
  • Globally, as of 3 July 2015, 1363 cases including 487 deaths due to MERS-CoV have been reported to WHO. (who.int)
  • Suspected cases identified will be sent to public hospitals for isolation and management until their specimens test negative for MERS-CoV. (gov.hk)
  • Early identification of MERS-CoV is important, but not all cases can be detected in a timely manner, especially mild or atypical cases. (gov.hk)
  • Among confirmed MERS-CoV cases reported to date, the case fatality proportion is approximately 35% (Centers for Disease Control and Prevention [CDC], 2015). (scdhec.gov)
  • Jordan is among countries in or near the Arabian Peninsula, where cases of Mers-CoV had been reported since 2012. (inquirer.net)
  • Treatment for MERS-CoV is directed at relieving symptoms and includes rest, fluids, pain relievers and oxygen therapy in severe cases. (mayoclinic.org)
  • Given the wide distribution of MERS cases in the Middle East, the virus probably exists in other hosts besides T perforatus , the authors note. (scienceblog.com)
  • There is no evidence of direct exposure to bats in the majority of human cases of MERS," Memish commented in the release. (scienceblog.com)
  • The Ministry of Health in Italy, through the European Unions Early Warning Response System has notified the World Health Organization (WHO) of an additional two laboratory-confirmed cases with Middle East respiratory syndrome coronavirus (MERS-CoV) in the country. (infectioncontroltoday.com)
  • IRAN (ISLAMIC REPUBLIC OF) practices in hospitals, the number of hospital-acquired cases of MERS has dropped significantly since 2015. (who.int)
  • A history of being in a health care facility (as a patient, worker, or visitor) within 14 days before symptom onset in a country or territory in or near the Arabian Peninsula,¹ in which recent health care-associated cases of MERS have been identified. (wisconsin.gov)
  • The continued emergence of Middle East Respiratory Syndrome (MERS) cases with a high case fatality rate stresses the need for the availability of effective antiviral treatments. (pnas.org)
  • MERS-CoV emerged in 2012, and over 1,300 cases have been reported, with a 30 percent fatality rate (Milne-Price et. (nih.gov)
  • The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) is of global concern: the virus has caused severe respiratory illness, with 111 confirmed cases and 52 deaths at the time of this article's publication. (nih.gov)
  • As these two drugs are already used in combination in the clinic for other infections, IFN-α2b and ribavirin should be considered for the management of MERS-CoV cases. (nih.gov)
  • Guidance on investigating Middle East respiratory syndrome coronavirus (MERS-CoV), public health management of suspected UK cases and advice to travellers. (www.gov.uk)
  • The cluster of (MERS-CoV) continues to evolve in South Korea, where 153 confirmed (one of these is the case confirmed in China) cases and 11 deaths have been reported as of 16 June 2015. (emergencydispatch.org)
  • This study examined the effect of disclosing a list of hospitals with Middle East respiratory syndrome coronavirus (MERS-CoV) patients on the number of laboratory-confirmed MERS-CoV cases in South Korea. (mdpi.com)
  • It reduced the number of confirmed MERS-CoV cases. (mdpi.com)
  • All cases of MERS have been linked to countries in and near the Arabian Peninsula. (nccid.ca)
  • Other countries that have reported MERS-CoV cases include the United States, France, Italy, Germany, Greece, the United Kingdom and the Republic of Korea (South Korea)-all of these cases had history of travelling to the Middle East. (nccid.ca)
  • Human-to-human transmission of MERS-CoV accounts for approximately half of all the MERS-CoV cases reported to date ( 2 ). (frontiersin.org)
  • Since the last update was published (October MERS situation update), a total of 12 laboratory-confirmed cases of MERS were reported globally including one healthcare worker. (who.int)
  • Since April 2012 and as of 18 April 2014, 275 laboratory-confirmed cases of MERS-CoV have been reported by local health authorities worldwide, including 98 deaths and 64 healthcare workers. (flutrackers.com)
  • There is therefore a continued risk of cases presenting in Europe following exposure in the Middle East and international surveillance for MERS-CoV cases is essential. (flutrackers.com)
  • This data file contains individual information on laboratory-confirmed MERS cases in South Korea in 2015. (datadryad.org)
  • As of 29 October 2015, 628 deaths from 1635 cases of MERS-CoV had been identified worldwide, a case fatality rate of 39.02% [ 4 ]. (pubmedcentralcanada.ca)
  • We present a first analysis of the environmental circumstances under which MERS-CoV cases have occurred in the Middle East, covering all case occurrences through May 2015, using ecological niche modeling approaches to map transmission risk. (ku.edu)
  • We documented geographic and environmental distributions of MERS-CoV cases across the Middle East, and offer preliminary mapping of transmission risk. (ku.edu)
  • Recently, at the end of December 2019, a cluster of pneumonia cases were reported from Wuhan city, Hubei Province, China, linked to a wet seafood market with a new coronavirus identified as the etiologic agent currently named SARS-CoV-2. (atlantis-press.com)
  • Currently, KSA continues to report MERS-CoV cases on weekly basis, but the overall number of nosocomial transmissions has significantly been reduced [ 4 - 7 ]. (atlantis-press.com)
  • Recently, at the end of December 2019, a cluster of pneumonia cases were reported from Wuhan city, Hubei Province, China, linked to a wet seafood market with a new coronavirus identified as the etiologic agent currently named Severe Acute Respiratory Syndrome (SARS-CoV-2) [ 8 , 9 ]. (atlantis-press.com)
  • The first known cases of MERS-CoV occurred in March 2012, and were identified retrospectively. (vic.gov.au)
  • Globally 1,474 confirmed cases of MERS-CoV have been reported to WHO with at least 515 related deaths [2]. (travelhealthpro.org.uk)
  • MERS-CoV transmission can occur in health care settings if suspected cases are not promptly identified and isolated. (travelhealthpro.org.uk)
  • There is currently no advisory against travel to countries of the Arabian Peninsula, or to countries reporting imported cases of MERS-CoV. (gov.kh)
  • Given lack of therapeutics or vaccines so far, prevention is critical since MERS-CoV appears endemic with ongoing cases. (hopkinsguides.com)
  • These measures are expected to reduce the rate of new cases of SARS-CoV-2. (eurekaselect.com)
  • Respiratory samples from confirmed KSA MERS cases from May to September 2013 were subjected to whole-genome deep sequencing, and 32 complete or partial sequences (20 were ?99% complete, 7 were 50 to 94% complete, and 5 were 27 to 50% complete) were obtained, bringing the total available MERS-CoV genomic sequences to 65. (ed.ac.uk)
  • Four KSA MERS-CoV phylogenetic clades were found, with 3 clades apparently no longer contributing to current cases. (ed.ac.uk)
  • A household cluster of 8 laboratory-confirmed MERS cases was reported in Najran Region during the last week of May. (blogspot.com)
  • 2 MERS-CoV is one of the high-priority pathogens identified by the WHO R&D Blueprint because of its high fatality rate (~35%) for severe cases, large geographical range of the reservoir and lack of medical countermeasures, with critical knowledge gaps in veterinary and human epidemiology, immunity and pathogenesis. (bmj.com)
  • 27 countries reported MERS cases globally show any significant di erence compared with cases reported during the same period from 2012 to 2016. (who.int)
  • 14% cases are health care professionals Clinical Features About 3 to 4 out of every 10 people reported with MERS have died. (studylib.net)
  • Cases of MERS have also been reported in France, Italy, Tunisia, and the United Kingdom (UK). (adidarwinian.com)
  • Confirmed cases of MERS-CoV have originated in the Arabian Peninsula and surrounding areas. (medicinenet.com)
  • World Health Organization (WHO 2014b) reported that 1/3 of the people that was infected with MERS have died with fatal cases of severe respiratory symptoms involving elderly and patients with previous serious medical problems. (rnspeak.com)
  • Because of the small number of cases identified for each particular places, there is very limited information on transmission, epidemic issues, severity and clinical impact creating small patches to fill a big hole in the puzzle that creates craze and scare over MERS-CoV. (rnspeak.com)
  • Middle East Respiratory Syndrome (MERS) is viral respiratory illness that is new to humans. (cdc.gov)
  • MERS-CoV is thought to be a zoonotic virus, which means it can pass from animals to humans. (medicalnewstoday.com)
  • Researchers from the University of Cambridge and the Pirbright Institute in the UK have identified key genetic changes in SARS-CoV-2 that may be responsible for the virus's jump from bats to humans. (news-medical.net)
  • MERS-CoV is an example of a zoonotic virus transmitted from animals to humans. (news-medical.net)
  • MERS‐CoV is a zoonotic virus (passed between animals and humans). (scdhec.gov)
  • Bats have long been suspected as the source of MERS-CoV because of genetic likenesses between betacoronaviruses found in bats and the MERS virus in humans. (scienceblog.com)
  • Middle East respiratory syndrome coronavirus (MERS-CoV) continues to cause outbreaks in humans as a result of spillover events from dromedaries. (sciencemag.org)
  • In contrast to humans, MERS-CoV-exposed dromedaries develop only very mild infections and exceptionally potent virus-neutralizing antibody responses. (sciencemag.org)
  • The newly emergent Middle East respiratory syndrome coronavirus (MERS-CoV) can cause severe pulmonary disease in humans, representing the second example of a highly pathogenic coronavirus, the first being SARS-CoV. (nih.gov)
  • plan to conduct further research to see whether one of their compounds could effectively treat both MERS and COVID-19 in humans. (eurekalert.org)
  • Here, we have used expert-opinion elicitation in order to obtain ideas on relative importance of MERS-CoV risk factors and estimates of transmission risks from various types of contact between humans and dromedaries. (frontiersin.org)
  • The recently identified Middle East Respiratory Syndrome Coronavirus (MERS-CoV) causes severe and fatal acute respiratory illness in humans. (unboundmedicine.com)
  • Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe respiratory disease in humans with a case fatality rate of over 39%, and poses a considerable threat to public health. (pubmedcentralcanada.ca)
  • MERS-CoV has not been previously identified in humans. (medicinenet.com)
  • have caused three zoonotic outbreaks, SARS-CoV in 2002-2003, MERS-CoV in 2012, and the. (nature.com)
  • Chinese social media reaction to the MERS-CoV and avian influenza A(H7N9) outbreaks. (biomedsearch.com)
  • Diagnostics play a central role in the early detection and control of outbreaks and can enable a more nuanced understanding of the disease kinetics and risk factors for the Middle East respiratory syndrome-coronavirus (MERS-CoV), one of the high-priority pathogens identified by the WHO. (bmj.com)
  • The MERS coronavirus has caused disease outbreaks across the Arabian Peninsula and spread to Europe several times. (scoop.it)
  • She has led the country through Middle East respiratory syndrome (MERS), Influenza A virus subtype H7N9 (bird flu) and Dengue fever outbreaks. (wikipedia.org)
  • Since 2012, when the virus emerged, almost 2000 laboratory-proven human infections with MERS-CoV have been reported to the World Health Organization (WHO), appearing primarily in the countries of the Arabian peninsula. (news-medical.net)
  • MERS-CoV infections outside the Arabian Peninsula ( 6 ). (cdc.gov)
  • If you've traveled to the Arabian Peninsula or a neighboring country and you develop a fever and symptoms of MERS-CoV within 14 days of returning, see your doctor and discuss your recent travel. (mayoclinic.org)
  • In this study, we have determined the MERS-CoV evolutionary rate, documented genetic variants of the virus and their distribution throughout the Arabian peninsula, and identified the genome positions under positive selection, important features for monitoring adaptation of MERS-CoV to human transmission and for identifying the source of infections. (ed.ac.uk)
  • Middle East Respiratory Syndrome commonly known as MERS-CoV is a type of viral respiratory illness originated mainly in the Arabian Peninsula . (pharmasocialmedia.net)
  • Other countries, outside of the Arabian Peninsula and surrounding countries, have detected MERS-CoV only in travelers from these areas. (medicinenet.com)
  • Here we show that immunogens based on full-length S DNA and S1 subunit protein elicit robust serum-neutralizing activity against several MERS-CoV strains in mice and non-human primates. (osti.gov)
  • Therefore, we herein established a SARS-CoV -2 spike (S) protein. (nature.com)
  • binding domain (RBD) in SARS-CoV -2 S protein and found. (nature.com)
  • Here, using SARS-CoV -2 S protein pseudovirus system. (nature.com)
  • Here we delineate the molecular basis of this specific interaction by presenting the first crystal structures of both the free receptor binding domain (RBD) of the MERS-CoV spike protein and its complex with CD26. (nih.gov)
  • The viral RBD is composed of a core subdomain homologous to that of the SARS-CoV spike protein, and a unique strand-dominated external receptor binding motif that recognizes blades IV and V of the CD26 β-propeller. (nih.gov)
  • Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of MERS-CoV ORF4a. (genetex.com)
  • Here, we constructed a recombinant rare serotype of the chimpanzee adenovirus 68 (AdC68) that expresses full-length MERS-CoV S protein (AdC68-S). Single intranasal immunization with AdC68-S induced robust and sustained neutralizing antibody and T cell responses in BALB/c mice. (unboundmedicine.com)
  • We also found that the expression of nucleocapsid (N) protein essential for MERS-CoV replication was decreased after resveratrol treatment. (biomedcentral.com)
  • Using an immune-focusing approach, we created self-assembling particles multivalently displaying critical regions of the MERS-CoV spike protein ─fusion peptide, heptad repeat 2, and receptor binding domain (RBD) ─ and tested their immunogenicity and protective capacity in rabbits. (eur.nl)
  • A receptor binding domain (RBD) in the MERS-CoV envelope-embedded spike protein specifically engages human CD26 (hCD26) to initiate viral entry. (semanticscholar.org)
  • The antibody reacts with S2 subunit of MERS-CoV (NCoV/Novel coronavirus) Spike protein (S protein) and full-length S protein. (cd-bioparticles.com)
  • This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant MERS-CoV (NCoV/Novel coronavirus) Spike Protein S2. (cd-bioparticles.com)
  • SIOUX FALLS, S.D.--( Business Wire / Korea Newswire ) February 18, 2016 -- SAB Biotherapeutics, Inc. (SAB), a leading biopharmaceutical development company, announced today it has produced a new human antibody therapeutic to treat the deadly Middle East respiratory syndrome coronavirus (MERS-CoV) utilizing its novel DiversitAb™ production platform. (newswire.co.kr)
  • Non-transfected (-) and transfected (+) 293T whole cell extracts (30 μg) were separated by 15% SDS-PAGE, and the membrane was blotted with MERS-CoV ORF4a antibody (GTX134869) diluted at 1:5000. (genetex.com)
  • Non-infected and infected Vero B4 whole cell extracts (20 μg) were separated by gradient gel, and the membrane was blotted with MERS-CoV ORF4a antibody (GTX134869) diluted at 1:1000. (genetex.com)
  • There are currently no references for MERS-CoV ORF4a antibody (GTX134869) . (genetex.com)
  • RBD-LS vaccination induced antibody responses of high magnitude and quality (avidity, MERS-CoV neutralizing capacity, and mucosal immunity) with cross-clade neutralization. (eur.nl)
  • Antibody-mediated protection against MERS-CoV in the murine model. (umaryland.edu)
  • It is not always possible to identify patients with MERS-CoV early because some have mild or unusual symptoms. (who.int)
  • MERS is a flu-like illness with signs and symptoms of pneumonia. (medicalnewstoday.com)
  • Many individuals with MERS may have a mild respiratory illness or no symptoms. (medicalnewstoday.com)
  • The incubation period for MERS (the time between exposed to MERS-CoV and the start of symptoms) is usually about 5 or 6 days, but can range from 2-14 days. (scdhec.gov)
  • COTABATO CITY - A 20-year-old girl from North Cotabato is currently under isolation at the Cotabato Regional and Medical Center (CRMC) here after she showed symptoms of the Middle East respiratory syndrome coronavirus (Mers-CoV), the hospital's chief confirmed Saturday. (inquirer.net)
  • Mers-CoV's incubation period is usually 5-6 days but can also range from 2-14 days and patients initially show mild symptoms akin to colds or no symptoms at all, according to the US Center for Disease Control. (inquirer.net)
  • It is not always possible to identify patients with MERS-CoV early because like other respiratory infections, the early symptoms of MERS-CoV are non-specific. (infectioncontroltoday.com)
  • MERS-CoV is a serious respiratory disease with common symptoms in patients that include fever, cough, shortness of breath, and breathing difficulties. (wisconsin.gov)
  • The incubation period for MERS-CoV (from exposure to when signs or symptoms appear), ranges from 2 to 14 days (most commonly less than a week, 5-6 days). (emergencydispatch.org)
  • We identified 78 close contacts and after 14 days of monitoring and isolation, none of the contacts presented symptoms and all tested negative for MERS-CoV. (eurosurveillance.org)
  • The time between when a person is exposed to MERS-CoV and when he or she starts to have symptoms is usually about 5 or 6 days, but can range from 2 to 14 days. (nccid.ca)
  • Health Secretary Enrique Ona earlier said that the OFW and his relatives are asymptomatic, meaning without MERS-CoV symptoms. (abs-cbn.com)
  • All contacts of potential or confirmed MERS-CoV infected patient should be monitored for development of respiratory symptoms. (hopkinsguides.com)
  • Severe complications of MERS include pneumonia and kidney failure. (scdhec.gov)
  • A member of a cluster of patients with severe acute respiratory illness (e.g., fever and pneumonia requiring hospitalization) of unknown etiology, in which MERS-CoV is being evaluated, in consultation with state and local health departments in the US. (wisconsin.gov)
  • For many people with MERS-CoV, more severe complications followed, such as pneumonia and kidney failure. (emergencydispatch.org)
  • not necessarily pneumonia) and close contact with a confirmed MERS case while the case was ill. (mn.us)
  • MERSCOV Unlikely Step 4 ● ● Any evidence of lung parenchymal disease, either clinical ( pneumonia/ hypoxia/ tachypnoea/ ARDS) ) or chest xray finding of consolidation? (studylib.net)
  • Persons with pre-existing major illnesses, including chronic diseases such as diabetes, chronic lung disease and immunodeficiency, are more likely to develop severe infections for MERS if exposed to the virus," a spokesman for the DH said. (gov.hk)
  • The public may visit the CHP's MERS page (www.chp.gov.hk/en/view_content/26511.html), the DH's Travel Health Service (www.travelhealth.gov.hk/english/popup/popup.html) or the WHO's latest news (www.who.int/csr/don/archive/disease/coronavirus_infections/en/) for more information and health advice. (gov.hk)
  • The spread of SARS-CoV-2 has caused one of the most dangerous pandemics in modern history, and infections with its cousin MERS-CoV have a fatality rate of almost 35%, according to the World Health Organization. (eurekalert.org)
  • The Ministry of Health (MOH} of the Kingdom of Cambodia and the Worl.d Health Organization (WHO) wish to inform the public that currently, there is no case related to the Middle East Respiratory Syndrome Corona virus (MERS-CoV) infections and the Ebola Virus Disease have been detected in Cambodia, so far. (gov.kh)
  • Objective: Due to this new context, the present study aimed to conduct a systematic study review on the global status of the new coronavirus (COVID-2019) and its aspects in comparison to the previous SARS-CoV infections and MERS-CoV. (eurekaselect.com)
  • The study reported here was done on the basis of inoculation of 3 male animals with a human isolate of MERS-CoV, and the study design we used imposed several limitations on how these data inform what occurs in natural infections. (blogspot.com)
  • Coronavirus infections : MERS-CoV (Middle Eastern respiratory syndrome coronavirus) (Somali). (or.us)
  • Close contact between a person and an infected camel appears to be necessary for the transmission of MERS-CoV. (medicalnewstoday.com)
  • Three main elements play a role in the transmission of MERS-CoV: the virus, the host and the environment. (news-medical.net)
  • All transmission has been linked to health care facilities where MERS patients were treated. (who.int)
  • All modes of transmission are not well understood but MERS-CoV has spread from ill people to others through close contact, such as caring for or living with an infected person. (scdhec.gov)
  • http://www.cdc.gov/coronavirus/MERS/about/transmission.html. (mayoclinic.org)
  • These data suggest the potential of MERS-CoV to be transmitted via contact or fomite transmission due to prolonged environmental presence. (eurosurveillance.org)
  • To date, MERS-CoV has demonstrated limited and unsustained human-to-human transmission. (canada.ca)
  • The results of our study are consistent with available, yet very limited, published data regarding the potential pathways of transmission of MERS-CoV at the animal-human interface. (frontiersin.org)
  • Incubation period for MERS-CoV is still largely unknown but has been reported as prolonged in one documented instance of person-to-person nosocomial transmission (9- 14 days). (canada.ca)
  • Middle Eastern respiratory syndrome coronavirus (MERS-CoV) has spread rapidly across much of the Middle East, but no quantitative mapping of transmission risk has been developed to date. (ku.edu)
  • hence, camel exposure may be a key limiting element in MERS-CoV transmission. (ku.edu)
  • IMPORTANCE MERS-CoV adaptation toward higher rates of sustained human-to-human transmission appears not to have occurred yet. (ed.ac.uk)
  • While MERS-CoV transmission currently appears weak, careful monitoring of changes in MERS-CoV genomes and of the MERS epidemic should be maintained. (ed.ac.uk)
  • The observation of phylogenetically related MERS-CoV in geographically diverse locations must be taken into account in efforts to identify the animal source and transmission of the virus. (ed.ac.uk)
  • That said - despite the ongoing frustration over the lack of timely and accurate information - the good news is we've seen no signs of any sustained or efficient transmission of the MERS virus outside of health care facilities or ( rarely ) large households. (blogspot.com)
  • All studies to date of the host ecology and transmission biology of MERS-CoV have been based on case reports, serological studies, and molecular sequence data. (biomedcentral.com)
  • Notably, MERS-CoV point-of-care tests are needed in order to optimise supportive care and to minimise transmission risk. (bmj.com)
  • Researchers reveal transmission rate of MERS co. (scoop.it)
  • It would appear the MERS-CoV has been circulating in the human population for greater than one year without detection and suggests independent transmission from an unknown source. (wordpress.com)
  • The virus is taxonomically similar to the severe acute respiratory syndrome coronavirus (SARS-CoV) and has been associated with serious respiratory illness. (news-medical.net)
  • agent, severe acute respiratory syndrome coronavirus 2 ( SARS-CoV -2), also known as. (nature.com)
  • Remdesivir (GS-5734) effectively inhibited MERS coronavirus (MERS-CoV) replication in vitro, and showed efficacy against Severe Acute Respiratory Syndrome (SARS)-CoV in a mouse model. (pnas.org)
  • however, the severe acute respiratory syndrome coronavirus (SARS-CoV) can cause severe respiratory illness. (canada.ca)
  • Links within 14 days a prior to illness 2 onset to affected areas b (i.e. residence, travel history) OR close contact c with a confirmed or probable case of MERS-CoV or a traveller or resident with any acute respiratory illness returning from an affected area b . (canada.ca)
  • Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) causes Severe Acute Respiratory Syndrome (SARS). (adidarwinian.com)
  • MERS-CoV is a type of coronavirus, similar to the one that caused SARS ( severe acute respiratory syndrome ) and the common cold . (medicinenet.com)
  • Prophylactic remdesivir treatment initiated 24 h prior to inoculation completely prevented MERS-CoV−induced clinical disease, strongly inhibited MERS-CoV replication in respiratory tissues, and prevented the formation of lung lesions. (pnas.org)
  • Patients should be managed as potentially infected when the clinical and epidemiological clues strongly suggest MERS-CoV, even if an initial test on a nasopharyngeal swab is negative. (who.int)
  • Patients' lower respiratory tract specimens should be tested when possible and repeat testing should be undertaken when clinical and epidemiological clues strongly suggest MERS. (gov.hk)
  • Our data show that remdesivir is a promising antiviral treatment against MERS that could be considered for implementation in clinical trials. (pnas.org)
  • The data presented here support testing of the efficacy of remdesivir treatment in the context of a MERS clinical trial. (pnas.org)
  • Some EIDs including Middle East Respiratory Syndrome (MERS) and Crimean-Congo Hemorrhagic Fever (CCHF) have had experimental vaccines tested in fewer than six clinical trials. (prnewswire.com)
  • Taken together, these data suggest that treatment of MERS-CoV infected rhesus macaques with IFN-α2b and ribavirin reduces virus replication, moderates the host response and improves clinical outcome. (nih.gov)
  • Due to its clinical similarities with SARS-CoV , it gained its name SAUDI-SARS . (pharmasocialmedia.net)
  • People at high risk of severe disease due to MERS-CoV should avoid close contact with animals when visiting farms or barn areas where the virus is known to be potentially circulating. (who.int)
  • The team also determined which animals contain cellular receptors that allow the virus to enter cells more effectively, zoning in on potential animals that acted as an intermediary host in facilitating SARS-CoV-2's zoonosis. (news-medical.net)
  • What is the endgame for SARS-CoV-2, the virus that is causing worldwide devastation? (news-medical.net)
  • MERS is a statutorily notifiable infectious disease and the CHP's PHLSB is capable of detecting the virus. (gov.hk)
  • This virus has been named the Middle East Respiratory Syndrome Coronavirus (MERS-CoV). (wisconsin.gov)
  • Remdesivir reduced the severity of disease, virus replication, and damage to the lungs when administered either before or after animals were infected with MERS-CoV. (pnas.org)
  • Sequence alignment indicates, among betacoronaviruses, a possible structural conservation for the region homologous to the MERS-CoV RBD core, but a high variation in the external receptor binding motif region for virus-specific pathogenesis such as receptor recognition. (nih.gov)
  • The compounds neutralized viruses in human airway cells and improved survival in mice infected with a deadly, closely related virus that causes Middle East respiratory syndrome (MERS). (eurekalert.org)
  • Another potent compound named 6j boosted the odds of survival in mice infected with MERS-CoV, slashed the amount of virus in the lungs, and prevented dangerous complications like lung edema. (eurekalert.org)
  • MANILA - The Department of Health (DOH) has directed the passengers who traveled with the overseas Filipino worker (OFW) who tested positive for Middle East Respiratory Syndrome-Corona Virus (MERS-CoV) to take steps to rule out the possibility that they may have been similarly exposed to the virus. (abs-cbn.com)
  • The NML can confirm detection of the virus using MERS-CoV specific nucleic acid amplification tests (NAATs) and/or sequencing and though virus isolation in tissue culture. (canada.ca)
  • A common theme in his research has been the study of virus: host interactions, and he has now moved to the University of Leeds where he is starting a new research group studying the virus: host interactions of MERS-CoV. (lshtm.ac.uk)
  • Electron microscopy and immunoelectron microscopy results demonstrate that MERS-CoV VLPs are structurally similar to the native virus. (pubmedcentralcanada.ca)
  • In this study, we constructed a series of cytoplasmic deletion mutants of MERS-CoV S and compared the efficiency with which they formed pseudotypes with vesicular stomatitis virus. (deepdyve.com)
  • MERS-CoV is a coronavirus , newly described virus first isolated in 2012. (hopkinsguides.com)
  • Scientists have analyzed tissue samples of animals infected with the MERS-CoV virus to determine the pathway of the virus to the cells. (cresa.cat)
  • Earlier this summer, in mBio: Airborne Fragments Of MERS-CoV Detected In Saudi Camel Barn , we saw some limited evidence that MERS could be an airborne virus. (blogspot.com)
  • This is the first report of MERS-CoV and respiratory virus molecular screening of returning pilgrims at points of entry in China from 2013 to 2015. (biomedcentral.com)
  • MERS - CoV merupakan suatu penyakit yang disebabkan oleh corona virus -mirip dengan virus yang ditemukan pada kelelawar-, pertama kali ditemukan di Arab Saudi pada tahun 2012. (wordpress.com)
  • Penelitian terbaru menunjukkan bahwa MERS - CoV ada di dalam susu unta yang tidak dipasteurisasi, meskipun disimpan pada suhu 4°C, virus masih dapat menular lebih dari 72 jam. (wordpress.com)
  • MERS is caused by a virus called Middle East Respiratory Syndrome Coronavirus (MERS-CoV), which belongs to the Coronavirus family of viruses. (adidarwinian.com)
  • MERS Virus belongs to the genus Betacoronavirus. (adidarwinian.com)
  • The virus, like MERS, may cause moderate to severe respiratory problems in individuals and appears to spread from person to person. (medicinenet.com)
  • MERS-CoV adalah singkatan dari Middle East Respiratory Syndrome Corona Virus. (web.id)
  • MERS-CoV adalah penyakit sindrom pernapasan yang disebabkan oleh virus Corona yang menyerang saluran pernapasan mulai dari yang ringan sampai berat. (web.id)
  • Testing for MERS-CoV is available at the Office of Laboratory Services by consultation with DIDE. (wvoems.org)
  • Researchers provide an overview of SARS-CoV-2 and its life cycle pathways, addressing the functional changes in the viral proteins, providing important strategic clues to help that may help in the ongoing development of therapies against COVID-19. (news-medical.net)
  • A new study reports the virucidal and fusion-inhibiting attributes of snake venom against the COVID-19 agent SARS-CoV-2. (news-medical.net)
  • and found that SARS-CoV -2 showed a. (nature.com)
  • currently no effective drugs targeting 2019-nCoV / SARS-CoV -2. (nature.com)
  • newly emerged SARS-CoV -2 in late 2019. (nature.com)
  • known about the biology of SARS-CoV -2. (nature.com)
  • hACE2) is the receptor for SARS-CoV -2, find that SARS-CoV -2. (nature.com)
  • Here, they tested several 3C-like protease inhibitors in cells infected with SARS-CoV-2, SARS-CoV, or MERS-CoV. (eurekalert.org)
  • One of the compounds, named 6e, showed strong activity against SARS-CoV-2 and inhibited viral replication by tenfold in cultured human airway epithelial cells taken from infected donors. (eurekalert.org)
  • SARS-CoV-2: What ' s in a Name? (medworm.com)
  • It is genetically distinct from the SARS CoV, and appears to behave differently. (vic.gov.au)
  • Major findings and conclusion: In some countries the SARS-CoV-2 pandemic appears to be out of control. (eurekaselect.com)
  • MERS-CoV is distinct from SARS and distinct from the common-cold coronavirus and known endemic human betacoronaviruses HCoV-OC43 and HCoV-HKU1. (wordpress.com)
  • MERS and Wuhan coronavirus are two other coronavirus types that are related to SARS . (medicinenet.com)
  • Similar to SARS, there is no medication that is known to treat MERS-CoV. (medicinenet.com)
  • MERS-CoV illness and length of incubation period. (cdc.gov)
  • Middle East respiratory syndrome coronavirus (MERS-CoV) is a WHO priority pathogen for which vaccines are urgently needed. (eur.nl)
  • Those who were aware of MERS-CoV were more likely to receive recommended vaccines [odds ratio (OR) 3.1, 95% confidence interval (CI): 1.5-5.9, P (ovid.com)
  • Middle East respiratory syndrome (MERS): MERS in the U.S. Centers for Disease Control and Prevention. (mayoclinic.org)
  • 20 September 2018 Added 'MERS-CoV: advice for people visiting healthcare settings' to the collection. (www.gov.uk)
  • 3 January 2014 - On 31 December 2013, WHO has been informed of an additional laboratory-confirmed case of Middle East Respiratory Syndrome coronavirus (MERS-CoV) in United Arab Emirates. (who.int)
  • The case is a 33 year-old male healthcare worker in Dubai who was in contact with the confirmed MERS-CoV case reported to WHO on 20 December. (who.int)
  • The case was laboratory confirmed for MERS-CoV on 29 December 2013. (who.int)
  • On 20 May 2015, the Republic of Korea reported its first laboratory-confirmed case of MERS-CoV. (who.int)
  • The Centre for Health Protection (CHP) of the Department of Health (DH) is today (June 4) investigating a suspected case of Middle East Respiratory Syndrome (MERS) whose respiratory specimen tested negative for MERS Coronavirus (MERS-CoV), and hence called on the public to stay alert and maintain good personal, food and environmental hygiene during travel. (gov.hk)
  • A previous MERS case in Asir involved a 66-year-old man and was reported by the MOH on Jul 8. (umn.edu)
  • The patient did not have known contact with a previously reported MERS-CoV case. (infectioncontroltoday.com)
  • Close contact² with a confirmed MERS case while the case was ill. (wisconsin.gov)
  • Middle East Respiratory Syndrome, caused by the MERS coronavirus (MERS-CoV), continues to cause severe respiratory disease with a high case fatality rate. (pnas.org)
  • On the 20th of May, one case of MERS-CoV was reported from Republic of Korea. (emergencydispatch.org)
  • Patients with the following known pre-existing medical conditions (also called comorbidities) may be more likely to become infected with MERS-CoV, or have a severe case. (emergencydispatch.org)
  • Individuals with weakened immune systems are also at higher risk for getting MERS or having a severe case. (emergencydispatch.org)
  • All receiving health care facilities should be notified, in advance, when a suspected case of MERS-CoV is to be transported to the facility. (emergencydispatch.org)
  • MERS-CoV confirmed case to WHO. (scribd.com)
  • Close contacts of a confirmed case of MERS. (nccid.ca)
  • e.g., cough, shortness of breath) AND close contact with a confirmed MERS case while the case was ill. (wvoems.org)
  • National surveillance case definitions are provided below - these are subject to change with ongoing monitoring and as understanding of MERS-CoV characteristics and risk evolve. (canada.ca)
  • A person epidemiologically-linked through close contact 1c to a laboratory-confirmed case and meeting illness criteria 2 but in whom laboratory diagnosis of MERS-CoV is not available or negative (if specimen quality or timing is suspect). (canada.ca)
  • On 20th May 2015, the Republic of Korea notified WHO of the first laboratoryconfirmed case of MERS-CoV. (studylib.net)
  • Pandemic potential risk for MERS-CoV does not exceed 5% (Brban et al. (scribd.com)
  • Most people infected with MERS-CoV developed severe respiratory illness, including fever, cough, and shortness of breath. (cdc.gov)
  • MERS-CoV belongs to the coronavirus family, the same family of viruses that cause the common cold. (medicalnewstoday.com)
  • Middle East respiratory syndrome (MERS) is a viral respiratory illness caused by a coronavirus - the same family of viruses that causes the common cold - called MERS-CoV. (mayoclinic.org)
  • Multiple neutralization mechanisms were demonstrated by solving the atomic structure of a NAb-RBD complex, through sequencing of neutralization escape viruses and by constructing MERS-CoV S variants for serological assays. (osti.gov)
  • There have been several reports of finding MERS-like viruses in animals. (scienceblog.com)
  • Graphic representation of the interaction between the MERS-CoV spike glycoprotein (blue-purple) and its receptor dipeptidyl peptidase 4 (DPP4). (nih.gov)
  • An electron micrograph of a thin section of MERS-CoV, showing the spherical particles within the cytoplasm of an infected cell. (cdc.gov)
  • MERS-CoV particles as seen by negative stain electron microscopy. (cdc.gov)
  • An electron micrograph of a thin section of MERS-CoV, showing the spherical particles and cross-sections through the viral nucleocapsid. (cdc.gov)
  • These are MERS coronavirus particles (green) on camel epithelial cells. (eurekalert.org)
  • Conclusions: The first external quality assessment MERS-CoV panel gives a good insight in molecular diagnostic techniques and their performances for sensitive and specific detection of MERS-CoV RNA globally. (eur.nl)
  • MERS-CoV is a viral respiratory disease. (www.gov.uk)
  • MERS is a viral respiratory illness and stands for Middle East Respiratory Syndrome. (adidarwinian.com)
  • MERS-CoV primarily causes fever, cough and shortness of breath. (mayoclinic.org)
  • A usual presentation of MERS-CoV disease involves fever, cough, muscle aches and shortness of breath. (nccid.ca)
  • A person meeting exposure 1 and illness 2 criteria and in whom laboratory screening test for MERS-CoV was positive but not confirmed by the NML. (canada.ca)
  • Recent travellers returning from the Middle East who develop SARI should be tested for MERS-CoV as advised in the current surveillance recommendations. (who.int)
  • Nearly a month ago, due to what appears to be an ongoing redesign of the Saudi MOH website, daily updates to the MERS-CoV surveillance portal halted, and all existing data since January 23rd of this year vanished from the site. (blogspot.com)
  • Furthermore, resveratrol down-regulated the apoptosis induced by MERS-CoV in vitro . (biomedcentral.com)
  • In this study, we first demonstrated that resveratrol is a potent anti-MERS agent in vitro . (biomedcentral.com)
  • In this study, we evaluated the antiviral effectiveness of resveratrol against MERS-CoV with an in vitro model. (biomedcentral.com)
  • According to the WHO, the rapid spread of the disease in South Korea was because of - among other things - a lack of awareness among the public and healthcare workers about MERS, crowded hospitals and emergency rooms, visitation by too many friends and family members and the practice of 'doctor shopping', or seeking care in multiple hospitals. (studylib.net)
  • About 3-4 out of every 10 patients reported with MERS have died. (emergencydispatch.org)
  • MERS patients range in age from younger than 1 to 99 years old. (nccid.ca)
  • Patients meeting MERS-CoV criteria above should be placed in Airborne and Contact Precautions , in addition to Standard Precautions. (mn.us)
  • Among animal reservoirs, CoV has a large genetic diversity yet the samples from patients suggest a similar genome, and therefore common source, though the data are limited. (wordpress.com)
  • Reference: Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo. (newswire.co.kr)
  • Objectives: We set out to assess the quality of MERS-CoV molecular diagnostics worldwide. (eur.nl)
  • Laboratory: molecular diagnostics are the method of choice for MERS-CoV. (hopkinsguides.com)
  • Background: Since the discovery of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012, diagnostic protocols were quickly published and deployed globally. (eur.nl)