Medicago truncatula: A plant species of the family FABACEAE used to study GENETICS because it is DIPLOID, self fertile, has a small genome, and short generation time.Medicago: A plant genus of the family FABACEAE. It is distinct from Sweet Clover (MELILOTUS), from Bush Clover (LESPEDEZA), and from Red Clover (TRIFOLIUM).Medicago sativa: A plant species of the family FABACEAE widely cultivated for ANIMAL FEED.Sinorhizobium meliloti: A species of gram-negative, aerobic bacteria that causes formation of root nodules on some, but not all, types of sweet clover, MEDICAGO SATIVA, and fenugreek.Root Nodules, Plant: Knobbed structures formed from and attached to plant roots, especially of LEGUMES, which result from symbiotic infection by nitrogen fixing bacteria such as RHIZOBIUM or FRANKIA. Root nodules are structures related to MYCORRHIZAE formed by symbiotic associations with fungi.Symbiosis: The relationship between two different species of organisms that are interdependent; each gains benefits from the other or a relationship between different species where both of the organisms in question benefit from the presence of the other.Plant Roots: The usually underground portions of a plant that serve as support, store food, and through which water and mineral nutrients enter the plant. (From American Heritage Dictionary, 1982; Concise Dictionary of Biology, 1990)Mycorrhizae: Symbiotic combination (dual organism) of the MYCELIUM of FUNGI with the roots of plants (PLANT ROOTS). The roots of almost all higher plants exhibit this mutually beneficial relationship, whereby the fungus supplies water and mineral salts to the plant, and the plant supplies CARBOHYDRATES to the fungus. There are two major types of mycorrhizae: ectomycorrhizae and endomycorrhizae.Plant Proteins: Proteins found in plants (flowers, herbs, shrubs, trees, etc.). The concept does not include proteins found in vegetables for which VEGETABLE PROTEINS is available.Nitrogen Fixation: The process in certain BACTERIA; FUNGI; and CYANOBACTERIA converting free atmospheric NITROGEN to biologically usable forms of nitrogen, such as AMMONIA; NITRATES; and amino compounds.Gene Expression Regulation, Plant: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in plants.Sinorhizobium: A genus of gram-negative, aerobic, nonsporeforming rods which usually contain granules of poly-beta-hydroxybutyrate. (From Bergey's Manual of Determinative Bacteriology, 9th ed)Workload: The total amount of work to be performed by an individual, a department, or other group of workers in a period of time.Melilotus: A plant genus of the family FABACEAE.Rhizobium: A genus of gram-negative, aerobic, rod-shaped bacteria that activate PLANT ROOT NODULATION in leguminous plants. Members of this genus are nitrogen-fixing and common soil inhabitants.Lotus: A plant genus of the family FABACEAE. This genus was formerly known as Tetragonolobus. The common name of lotus is also used for NYMPHAEA and NELUMBO.Genome, Plant: The genetic complement of a plant (PLANTS) as represented in its DNA.Plants, Genetically Modified: PLANTS, or their progeny, whose GENOME has been altered by GENETIC ENGINEERING.Aphanomyces: A genus of OOMYCETES in the family Saprolegniaceae. It causes root rot in plants and is also a pathogen of FISHES.Fabaceae: The large family of plants characterized by pods. Some are edible and some cause LATHYRISM or FAVISM and other forms of poisoning. Other species yield useful materials like gums from ACACIA and various LECTINS like PHYTOHEMAGGLUTININS from PHASEOLUS. Many of them harbor NITROGEN FIXATION bacteria on their roots. Many but not all species of "beans" belong to this family.Trifolium: A plant genus of the family FABACEAE.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.DNA, Plant: Deoxyribonucleic acid that makes up the genetic material of plants.Seeds: The encapsulated embryos of flowering plants. They are used as is or for animal feed because of the high content of concentrated nutrients like starches, proteins, and fats. Rapeseed, cottonseed, and sunflower seed are also produced for the oils (fats) they yield.Plant Leaves: Expanded structures, usually green, of vascular plants, characteristically consisting of a bladelike expansion attached to a stem, and functioning as the principal organ of photosynthesis and transpiration. (American Heritage Dictionary, 2d ed)Synteny: The presence of two or more genetic loci on the same chromosome. Extensions of this original definition refer to the similarity in content and organization between chromosomes, of different species for example.Phylogeny: The relationships of groups of organisms as reflected by their genetic makeup.Proanthocyanidins: Dimers and oligomers of flavan-3-ol units (CATECHIN analogs) linked mainly through C4 to C8 bonds to leucoanthocyanidins. They are structurally similar to ANTHOCYANINS but are the result of a different fork in biosynthetic pathways.Expressed Sequence Tags: Partial cDNA (DNA, COMPLEMENTARY) sequences that are unique to the cDNAs from which they were derived.RNA, Plant: Ribonucleic acid in plants having regulatory and catalytic roles as well as involvement in protein synthesis.Trigonella: A plant genus of the family FABACEAE.Plant Shoots: New immature growth of a plant including stem, leaves, tips of branches, and SEEDLINGS.Seedling: Very young plant after GERMINATION of SEEDS.Indoleacetic Acids: Acetic acid derivatives of the heterocyclic compound indole. (Merck Index, 11th ed)Leghemoglobin: A hemoglobin-like oxygen-binding hemeprotein present in the nitrogen-fixing root nodules of leguminous plants. The red pigment has a molecular weight approximately 1/4 that of hemoglobin and has been suggested to act as an oxido-reduction catalyst in symbiotic nitrogen fixation.Chromosomes, Plant: Complex nucleoprotein structures which contain the genomic DNA and are part of the CELL NUCLEUS of PLANTS.Glomeromycota: A phylum of fungi that are mutualistic symbionts and form ARBUSCULAR MYCORRHIZAE with PLANT ROOTS.Plant Diseases: Diseases of plants.Cytokinins: Plant hormones that promote the separation of daughter cells after mitotic division of a parent cell. Frequently they are purine derivatives.Peas: A variable annual leguminous vine (Pisum sativum) that is cultivated for its rounded smooth or wrinkled edible protein-rich seeds, the seed of the pea, and the immature pods with their included seeds. (From Webster's New Collegiate Dictionary, 1973)Agrobacterium: A genus of gram negative, aerobic, rod-shaped bacteria found in soil, plants, and marine mud.Plant Growth Regulators: Any of the hormones produced naturally in plants and active in controlling growth and other functions. There are three primary classes: auxins, cytokinins, and gibberellins.Lignin: The most abundant natural aromatic organic polymer found in all vascular plants. Lignin together with cellulose and hemicellulose are the major cell wall components of the fibers of all wood and grass species. Lignin is composed of coniferyl, p-coumaryl, and sinapyl alcohols in varying ratios in different plant species. (From Merck Index, 11th ed)Ethylenes: Derivatives of ethylene, a simple organic gas of biological origin with many industrial and biological use.Plant Structures: The parts of plants, including SEEDS.Rhizobiaceae: A family of gram-negative bacteria which are saprophytes, symbionts, or plant pathogens.Plant Stems: Parts of plants that usually grow vertically upwards towards the light and support the leaves, buds, and reproductive structures. (From Concise Dictionary of Biology, 1990)Naphthaleneacetic Acids: Naphthalene derivatives containing the -CH2CCO2H radical at the 1-position, the 2-position, or both. Compounds are used as plant growth regulators to delay sprouting, exert weed control, thin fruit, etc.Colletotrichum: A genus of mitosporic Phyllachoraceae fungi which contains at least 40 species of plant parasites. They have teleomorphs in the genus Glomerella (see PHYLLACHORALES).Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Meristem: A group of plant cells that are capable of dividing infinitely and whose main function is the production of new growth at the growing tip of a root or stem. (From Concise Dictionary of Biology, 1990)Cicer: A plant genus of the family FABACEAE known for the edible beans.Gene Expression Profiling: The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.Plant Epidermis: A thin layer of cells forming the outer integument of seed plants and ferns. (Random House Unabridged Dictionary, 2d ed)Lupinus: A plant genus of the family FABACEAE that is a source of SPARTEINE, lupanine and other lupin alkaloids.Pulvinus: A group of cells at the base of a leaf in certain plants that, by rapidly losing water, brings about changes in the position of the leaves. (Concise Dictionary of Biology, 1990)Soybeans: An annual legume. The SEEDS of this plant are edible and used to produce a variety of SOY FOODS.Germination: The initial stages of the growth of SEEDS into a SEEDLINGS. The embryonic shoot (plumule) and embryonic PLANT ROOTS (radicle) emerge and grow upwards and downwards respectively. Food reserves for germination come from endosperm tissue within the seed and/or from the seed leaves (COTYLEDON). (Concise Dictionary of Biology, 1990)Aphids: A family (Aphididae) of small insects, in the suborder Sternorrhyncha, that suck the juices of plants. Important genera include Schizaphis and Myzus. The latter is known to carry more than 100 virus diseases between plants.Chromosome Mapping: Any method used for determining the location of and relative distances between genes on a chromosome.Entomophthora: A genus of fungi in the family Entomophthoraceae, order Entomorphthorales. They are primarily parasites of insects and spiders, but have been found to cause mycotic infections of the nose in man and horses.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Flowers: The reproductive organs of plants.Nitrogen: An element with the atomic symbol N, atomic number 7, and atomic weight [14.00643; 14.00728]. Nitrogen exists as a diatomic gas and makes up about 78% of the earth's atmosphere by volume. It is a constituent of proteins and nucleic acids and found in all living cells.Thioredoxin h: A thioredoxin subtype that is ubiquitously found in the plant kingdom. It reduces a variety of seed storage proteins and may play a role in the germination process of seeds.Multigene Family: A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed on different chromosomes. Examples of multigene families include those that encode the hemoglobins, immunoglobulins, histocompatibility antigens, actins, tubulins, keratins, collagens, heat shock proteins, salivary glue proteins, chorion proteins, cuticle proteins, yolk proteins, and phaseolins, as well as histones, ribosomal RNA, and transfer RNA genes. The latter three are examples of reiterated genes, where hundreds of identical genes are present in a tandem array. (King & Stanfield, A Dictionary of Genetics, 4th ed)Orobanche: A plant genus of the family OROBANCHACEAE. Lacking chlorophyll, they are nonphotosynthetic parasitic plants. The common name is similar to Broom or Scotch Broom (CYTISUS) or Butcher's Broom (RUSCUS) or Desert Broom (BACCHARIS) or Spanish Broom (SPARTIUM) or Brome (BROMUS).Plant Tumors: A localized proliferation of plant tissue forming a swelling or outgrowth, commonly with a characteristic shape and unlike any organ of the normal plant. Plant tumors or galls usually form in response to the action of a pathogen or a pest. (Holliday, P., A Dictionary of Plant Pathology, 1989, p330)Glutamate Synthase (NADH): A FLAVOPROTEIN enzyme for AMMONIA assimilation in BACTERIA, microorganisms and PLANTS. It catalyzes the oxidation of 2 molecules of L-GLUTAMATE to generate L-GLUTAMINE and 2-oxoglutarate in the presence of NAD+.Sequence Analysis, DNA: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.Lens Plant: A plant genus of the FABACEAE family known for the seeds used as food.Phloem: Plant tissue that carries nutrients, especially sucrose, by turgor pressure. Movement is bidirectional, in contrast to XYLEM where it is only upward. Phloem originates and grows outwards from meristematic cells (MERISTEM) in the vascular cambium. P-proteins, a type of LECTINS, are characteristically found in phloem.Phaseolus: A plant genus in the family FABACEAE which is the source of edible beans and the lectin PHYTOHEMAGGLUTININS.Plant Vascular Bundle: A strand of primary conductive plant tissue consisting essentially of XYLEM, PHLOEM, and CAMBIUM.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Pterocarpans: A group of compounds which can be described as benzo-pyrano-furano-benzenes which can be formed from ISOFLAVONES by internal coupling of the B ring to the 4-ketone position. Members include medicarpin, phaseolin, and pisatin which are found in FABACEAE.Sequence Alignment: The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.Sequence Homology, Amino Acid: The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.Arachis hypogaea: A plant species of the family FABACEAE that yields edible seeds, the familiar peanuts, which contain protein, oil and lectins.Cotyledon: A part of the embryo in a seed plant. The number of cotyledons is an important feature in classifying plants. In seeds without an endosperm, they store food which is used in germination. In some plants, they emerge above the soil surface and become the first photosynthetic leaves. (From Concise Dictionary of Biology, 1990)
On the species of origin: diagnosing the source of symbiotic transcripts. (1/168)BACKGROUND: Most organisms have developed ways to recognize and interact with other species. Symbiotic interactions range from pathogenic to mutualistic. Some molecular mechanisms of interspecific interaction are well understood, but many remain to be discovered. Expressed sequence tags (ESTs) from cultures of interacting symbionts can help identify transcripts that regulate symbiosis, but present a unique challenge for functional analysis. Given a sequence expressed in an interaction between two symbionts, the challenge is to determine from which organism the transcript originated. For high-throughput sequencing from interaction cultures, a reliable computational approach is needed. Previous investigations into GC nucleotide content and comparative similarity searching provide provisional solutions, but a comparative lexical analysis, which uses a likelihood-ratio test of hexamer counts, is more powerful. RESULTS: Validation with genes whose origin and function are known yielded 94% accuracy. Microbial (non-plant) transcripts comprised 75% of a Phytophthora sojae-infected soybean (Glycine max cv Harasoy) library, contrasted with 15% or less in root tissue libraries of Medicago truncatula from axenic, Phytophthora medicaginis-infected, mycorrhizal, and rhizobacterial treatments. Mycorrhizal libraries contained about 23% microbial transcripts; an axenic plant library contained a similar proportion of putative microbial transcripts. CONCLUSIONS: Comparative lexical analysis offers numerous advantages over alternative approaches. Many of the transcripts isolated from mixed cultures were of unknown function, suggesting specificity to symbiotic metabolism and therefore candidates likely to be interesting for further functional investigation. Future investigations will determine whether the abundance of non-plant transcripts in a pure plant library indicates procedural artifacts, horizontally transferred genes, or other phenomena. (+info)
A phosphate transporter gene from the extra-radical mycelium of an arbuscular mycorrhizal fungus Glomus intraradices is regulated in response to phosphate in the environment. (2/168)The majority of vascular flowering plants are able to form symbiotic associations with arbuscular mycorrhizal fungi. These symbioses, termed arbuscular mycorrhizas, are mutually beneficial, and the fungus delivers phosphate to the plant while receiving carbon. In these symbioses, phosphate uptake by the arbuscular mycorrhizal fungus is the first step in the process of phosphate transport to the plant. Previously, we cloned a phosphate transporter gene involved in this process. Here, we analyze the expression and regulation of a phosphate transporter gene (GiPT) in the extra-radical mycelium of the arbuscular mycorrhizal fungus Glomus intraradices during mycorrhizal association with carrot or Medicago truncatula roots. These analyses reveal that GiPT expression is regulated in response to phosphate concentrations in the environment surrounding the extra-radical hyphae and modulated by the overall phosphate status of the mycorrhiza. Phosphate concentrations, typical of those found in the soil solution, result in expression of GiPT. These data imply that G. intraradices can perceive phosphate levels in the external environment but also suggest the presence of an internal phosphate sensing mechanism. (+info)
Overlapping plant signal transduction pathways induced by a parasitic nematode and a rhizobial endosymbiont. (3/168)Root-knot nematodes and rhizobia establish interactions with roots characterized by the de novo induction of host structures, termed giant cells and nodules, respectively. Two transcription regulators, PHAN and KNOX, required for the establishment of meristems were previously shown to be expressed in tomato giant cells. We isolated the orthologues of PHAN and KNOX (Mt-phan and Mt-knox-1) from the model legume Medicago truncatula, and established the spatial distribution of their expression in situ. We confirmed that Mt-phan and Mt-knox-1 are expressed in lateral root initials and in nematode-induced giant cells and showed that they are expressed in nodules induced by Sinorhizobium meliloti. Expression of both genes becomes spatially restricted as the nodules develop. We further examined nematode feeding sites for the expression of two genes involved in nodule formation, ccs52 (encodes a mitotic inhibitor) and ENOD40 (encodes an early, nodulation mitogen), and found transcripts of both genes to be present in and around giant cells induced in Medicago. Collectively, these results reveal common elements of host responses to mutualistic and parasitic plant endosymbionts and imply that overlapping regulatory pathways lead to giant cells and nodules. We discuss these pathways in the context of phytohormones and parallels between beneficial symbiosis and disease. (+info)
Salmonella Typhimurium infections transmitted by chlorine-pretreated clover sprout seeds. (4/168)Raw seed sprouts have caused numerous outbreaks of enteric infections. Presoaking seeds in a 20,000 mg/liter (ppm) calcium hypochlorite solution before sprouting is recommended to reduce bacterial contamination and infection risk. In 1999, the authors investigated an outbreak of Salmonella serotype Typhimurium infections in Colorado. In a case-control study, they matched 20 cases with 58 controls by age, sex, and telephone prefix; 10 (52%) of 19 cases and no controls recalled eating raw alfalfa-style sprouts in the 5 days before the patient's illness (p < 0.00001). Traceback implicated clover sprouts grown from seeds shared by two sprouters. The time period and region over which these sprouts were sold matched the occurrences of 112 culture-confirmed illnesses. Only one of the sprouters presoaked seeds as recommended, and fewer infections were attributable to this sprouter (0.29 vs. 1.13 culture-confirmed infections/50-pound (110.1-kg) bag of seed). After recall of the implicated sprouts and seed, S. Typhimurium illnesses declined. Contaminated raw clover sprouts can cause outbreaks of enteric illness. Presoaking contaminated seeds in a 20,000 mg/liter calcium hypochlorite solution reduces, but does not eliminate, the risk of infection. Until safer production methods are developed, persons eating raw sprouts continue to risk developing potentially serious gastrointestinal illness. (+info)
Medicago truncatula plants overexpressing the early nodulin gene enod40 exhibit accelerated mycorrhizal colonization and enhanced formation of arbuscules. (5/168)The mutualistic symbiosis between flowering plants and arbuscular mycorrhizal fungi is extremely abundant in terrestrial ecosystems. In this symbiosis, obligately biotrophic fungi colonize the root of the host plants, which can benefit from these fungi by enhanced access to mineral nutrients in the soil, especially phosphorus. One of the main goals of research on this symbiosis is to find plant genes that control fungal development in the host plant. In this work, we show that mycorrhizal colonization is regulated by enod40, an early nodulin gene known to be involved in the nodule symbiosis of legumes with nitrogen-fixing bacteria. Medicago truncatula plants overexpressing enod40 exhibited stimulated mycorrhizal colonization in comparison with control plants. Overexpression of enod40 promoted fungal growth in the root cortex and increased the frequency of arbuscule formation. Transgenic lines with suppressed levels of enod40 transcripts, likely via a cosuppression phenomenon induced by the transgene, exhibited reduced mycorrhizal colonization. Hence, enod40 might be a plant regulatory gene involved in the control of the mycorrhizal symbiosis. (+info)
Immunodominant membrane proteins from two phytoplasmas in the aster yellows clade (chlorante aster yellows and clover phyllody) are highly divergent in the major hydrophilic region. (6/168)The mechanisms by which phytoplasmas interact with their hosts are not understood. Mollicute membrane proteins may play a role in such interactions and therefore the amp genes encoding immunodominant proteins from two phytoplasmas, aster yellows and clover phyllody, which fall within the largest taxonomic subclade of the phytoplasmas, have been cloned and characterized. The putative translation products, antigenic membrane proteins (Amps), of these genes have properties which are typical for bacterial membrane proteins, and which suggest that each has a single large extracellular hydrophilic domain held by a transmembrane region near the C-terminus, with only a short C-terminal intracellular sequence. Both of the Amps characterized here have bacterial leader sequences which are cleaved during maturation. Whilst the signal peptide and transmembrane regions of the two proteins are very similar, the major hydrophilic domains are highly divergent in both size and sequence. The Amps from the two phytoplasmas are also different in structure and sequence from the immunodominant membrane proteins of three other phytoplasmas whose genes have been cloned previously. (+info)
The molecular genetic linkage map of the model legume Medicago truncatula: an essential tool for comparative legume genomics and the isolation of agronomically important genes. (7/168)BACKGROUND: The legume Medicago truncatula has emerged as a model plant for the molecular and genetic dissection of various plant processes involved in rhizobial, mycorrhizal and pathogenic plant-microbe interactions. Aiming to develop essential tools for such genetic approaches, we have established the first genetic map of this species. Two parental homozygous lines were selected from the cultivar Jemalong and from the Algerian natural population (DZA315) on the basis of their molecular and phenotypic polymorphism. RESULTS: An F2 segregating population of 124 individuals between these two lines was obtained using an efficient manual crossing technique established for M. truncatula and was used to construct a genetic map. This map spans 1225 cM (average 470 kb/cM) and comprises 289 markers including RAPD, AFLP, known genes and isoenzymes arranged in 8 linkage groups (2n = 16). Markers are uniformly distributed throughout the map and segregation distortion is limited to only 3 linkage groups. By mapping a number of common markers, the eight linkage groups are shown to be homologous to those of diploid alfalfa (M. sativa), implying a good level of macrosynteny between the two genomes. Using this M. truncatula map and the derived F3 populations, we were able to map the Mtsym6 symbiotic gene on linkage group 8 and the SPC gene, responsible for the direction of pod coiling, on linkage group 7. CONCLUSIONS: These results demonstrate that Medicago truncatula is amenable to diploid genetic analysis and they open the way to map-based cloning of symbiotic or other agronomically-important genes using this model plant. (+info)
Pharmacological analysis of nod factor-induced calcium spiking in Medicago truncatula. Evidence for the requirement of type IIA calcium pumps and phosphoinositide signaling. (8/168)Bacterial Nod factors trigger a number of cellular responses in root hairs of compatible legume hosts, which include periodic, transient increases in cytosolic calcium levels, termed calcium spiking. We screened 13 pharmaceutical modulators of eukaryotic signal transduction for effects on Nod factor-induced calcium spiking. The purpose of this screening was 2-fold: to implicate enzymes required for Nod factor-induced calcium spiking in Medicago sp., and to identify inhibitors of calcium spiking suitable for correlating calcium spiking to other Nod factor responses to begin to understand the function of calcium spiking in Nod factor signal transduction. 2-Aminoethoxydiphenylborate, caffeine, cyclopiazonic acid (CPA), 2,5-di-(t-butyl)-1,4-hydroquinone, and U-73122 inhibit Nod factor-induced calcium spiking. CPA and U-73122 are inhibitors of plant type IIA calcium pumps and phospholipase C, respectively, and implicate the requirement for these enzymes in Nod factor-induced calcium spiking. CPA and U-73122 inhibit Nod factor-induced calcium spiking robustly at concentrations with no apparent toxicity to root hairs, making CPA and U-73122 suitable for testing whether calcium spiking is causal to subsequent Nod factor responses. (+info)
Scientists once gravitated toward thinking that non-legumes, which are not infected by rhizobia, just werent capable of receiving the NOD factor signal. But, a less popular theory guessed that plants like corn do receive the NOD factor signal but interpret it differently or have a problem with the mechanistic pathway.. Stacey said figuring out which is happening is like fixing a motion-detecting light.. "If you walk into a room and the light doesnt turn on, either the motion detector is broken or theres a breakdown of the electrical circuit between the detector and the light bulb," Stacey said. "The analogy in a corn plant would be that it either doesnt recognize the signal or recognizes the signal but lacks the ability to couple it with downstream developmental effects.". Staceys lab set out to determine which was true.. Corn, soybean, tomato and Arabidopsis were treated with bacterial flagellin, a protein known to cause a strong immune response, and also received doses of the NOD factor. ...
Nod factor-induced phospholipid signalling in legumes
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Salt stress alters DNA methylation levels in alfalfa (Medicago spp) - Fingerprint - Sultan Qaboos University: OMAN House...
Medicago truncatula Genome Project :: Mutant Information :: References
Frontiers | Ultrastructural and Cytological Studies on Mycosphaerella pinodes Infection of the Model Legume Medicago truncatula...
Ascochyta (Mycosphaerella) blight on cultivated peas is primarily caused by infection through asexual spores (pycnospores) of Mycosphaerella pinodes (Berk. et Blox.) Vestergren [recently renamed Peyronellaea pinodes (Berk. & A. Bloxam) Aveskamp, Gruyter & Verkley]. Using a recently developed model pathosystem involving Medicago truncatula and M. pinodes strain OMP-1, we examined the histology and ultrastructure of early infection events and fungal development including penetration by appressoria, vegetative growth of infection hyphae, and host responses. On the susceptible ecotype R108-1, pycnospores germinated and grew over the surface of the epidermis, then formed an appressoria and penetrated the cuticle. Beneath the cuticle, the infection peg expanded into a hyphae that grew within the outer wall of the epidermis. Subsequently, the hyphae penetrated down within mesophyll cells and proliferated vigorously, eventually, forming asexual fruiting bodies (pycnidia). In contrast, successful penetration and
Botany & Plant Biology 2007 - Abstract Search
Plant-Symbiont Interactions. Venkateshwaran, Muthusubramanian , Riely, Brendan K. , Peiter, Edgar , Sun, Jongho , Heckmann, Anne B. , Lougnon, Geraldine , Edwards, Anne , Otegui, Marisa , Freshour, Glenn , Hahn, Michael G. , Sanders, Dale , Oldroyd, Giles E. D. , Downie, Allan J. , Cook, Douglas R. , Ane, Jean-Michel . Medicago truncatula DMI1 localizes to the nuclear envelope and regulates Nod factor-induced calcium spiking.. In addition to establishing symbiotic relationships with arbuscular mycorrhizal fungi, legumes also enter into a nitrogen-fixing symbiosis with rhizobial bacteria that result in the formation of root nodules. Several genes required for the development of these symbioses have been cloned in model legumes. Among them, the M. truncatula DMI1 protein shares strong homologies with prokaryotic ion channels such as MthK. Two DMI1 homologs in L. japonicus, named CASTOR and POLLUX, have been localized in plastids. However our studies ...
Establishment of a root proteome reference map for the model legume Medicago truncatula using the expressed sequence tag...
Medicago truncatula ENOD11 protein Summary Report | CureHunter
Frontiers | Identification and Network-Enabled Characterization of Auxin Response Factor Genes in Medicago truncatula | Plant...
The Auxin Response Factor (ARF) family of transcription factors is an important regulator of environmental response and symbiotic nodulation in the legume Medicago truncatula. While previous studies have identified members of this family, a recent spurt in gene expression data coupled with genome update and reannotation calls for a reassessment of the prevalence of ARF genes and their interaction networks in M. truncatula. We performed a comprehensive analysis of the M. truncatula genome and transcriptome that entailed search for novel ARF genes and the co-expression networks. Our investigation revealed 8 novel M. truncatula ARF (MtARF) genes, of the total 22 identified, and uncovered novel gene co-expression networks as well. Furthermore, the topological clustering and single enrichment analysis of several network models revealed the roles of individual members of the MtARF family in nitrogen regulation, nodule initiation, and post-embryonic development through a specialized protein packaging and
Development of a software infrastructure to mine GeneChip expression data and to combine datasets from different Medicago...
Medicago truncatula is a model plant for studying legume biology. The ability to interact with beneficial microbial organisms leading to the formation of nitrogen fixing root nodules and to phosphate-acquiring arbuscular mycorriza (AM) is one of the main distinctive features of this family of plants. The two different symbioses of Medicago truncatula are investigated by various international research projects. Oligonucleotide microarrays are a robust technique to examine the expression of thousands of genes in parallel. Affymetrix GeneChips®, more recently designed gene-specific chips, make it easier for the researcher to compare and evaluate gene expression and thus will most certainly lead to more accurate results. Not surprisingly, Medicago GeneChips® are moving into the focus of gene expression analysis research in this model plant. Software applications for the analysis of GeneChips® are mostly commercial, or implemented as command-line tools without a user interface. Furthermore, a ...
Sinorhizobium medicae (strain WSM419) (Ensifer medicae)
Production and Characterization of Diverse Developmental Mutants of Medicago truncatula | Plant Physiology
The molecular dissection of plant growth and development in model plants such as Arabidopsis has largely relied on genetic approaches involving the isolation and subsequent characterization of mutants affected in specific biological processes. The utility of this approach now encompasses virtually every facet of plant biology, beginning from plant embryogenesis to flowering and senescence, and plant-pathogen interactions.. Despite the general validity of Arabidopsis as a model plant species, several biological processes do not occur in Arabidopsis and are better studied in other species. Examples of such species-processes combinations include tomato for climacteric fruit ripening, maize for regulation of seed storage protein biosynthesis, and legumes for study of plant symbiotic interactions with nitrogen-fixing bacteria (collectively termed rhizobia) and fungal symbionts (collectively termed mycorrhizae).. In contrast to the large impact plant mutants have had on a molecular dissection of plant ...
A genetic screen for plant mutants with altered nodulation phenotypes in response to rhizobial glycan mutants - Forskning -...
Nodule primordia induced by rhizobial glycan mutants often remain uninfected. To identify processes involved in infection and organogenesis we used forward genetics to identify plant genes involved in perception and responses to bacterial glycans. To dissect the mechanisms underlying the negative plant responses to the Mesorhizobium loti R7AexoU and ML001cep mutants, a screen for genetic suppressors of the nodulation phenotypes was performed on a chemically mutagenized Lotus population. Two mutant lines formed infected nitrogen-fixing pink nodules, while five mutant lines developed uninfected large white nodules, presumably altered in processes controlling organogenesis. Genetic mapping identified a mutation in the cytokinin receptor Lhk1 resulting in an alanine to valine substitution adjacent to a coiled-coil motif in the juxta-membrane region of LHK1. This results in a spontaneous nodulation phenotype and increased ethylene production. The allele was renamed snf5, and segregation studies of ...
All Publications | Max Planck Institute of Molecular Plant Physiology
Kuester, H.; Hohnjec, N.; Krajinski, F.; El Yahyaoui, F.; Manthey, K.; Gouzy, J.; Dondrup, M.; Meyer, F.; Kalinowski, J.; Brechenmacher, L. et al.; van Tuinen, D.; Gianinazzi-Pearson, V.; Puehler, A.; Gamas, P.; Becker, A.: Construction and validation of cDNA-based Mt6k-RIT macro- and microarrays to explore root endosymbioses in the model legume Medicago truncatula. Journal of Biotechnology 108 (2), pp. 95 - 113 (2004 ...
Medicago lupulina - Species Page - ISB: Atlas of Florida Plants
Medicago Reports Positive Phase I Results for its Avian Flu Pandemic Vaccine | Pressemitteilung Medicago
Comparative Genetic Mapping and Discovery of Linkage Disequilibrium Across Linkage Groups in White Clover (Trifolium repens L.)...
The original aim of this study was to develop EST-SSR markers and linkage maps for molecular genetics analysis in white clover. We achieved this by generating 1973 WCS markers and an integrated map with 1743 loci. WGS markers were designed based on the accumulated 7982 non-redundant white clover EST sequences. Although the number of accumulated EST sequences was limited, the proportion of KOG functional categories represented by the accumulated EST sequences was comparable to the proportion predicted in the genomes of Arabidopsis, L. japonicas, and rice. In addition, the distribution of the identified SSR motifs in the accumulated white clover EST sequences was basically similar to the distribution found in the genomes of other legume species, such as L. japonicas (Sato et al. 2008). Therefore, no specific bias should be observed in the accumulated white clover EST sequences.. In parallel, we discovered the existence of LD across linkage groups on the T17-349-specific map. Although the ...
Leaf anatomy of the South African Danthonieae (Poaceae). VII. Merxmuellera decora, M. lupulina and M. rufa | Ellis |...
Bothalia: African Biodiveristy & Conservation is published by AOSIS for the South African National Biodiversity Institute (SANBI) and aims to disseminate knowledge, information and innovative approaches that promote and enhanve the wise use and management of biodiversity in order to sustain the systems and species that support and benefit the people of Africa. The journal was previously publishd as Bothalia, and had served the South African botanical community since 1921. However the expande mandate of SANBI necessitated a broader scope for the journal, and in 2017, the subtitle, African Biodiversity & Conservation was added to reflect this change.
Medicago truncatula Genome Database | J. Craig Venter Institute
JCVI hosts the M. truncatula genome sequence and annotation in three forms: a Tripal database, JBrowse and an instance of InterMine named MedicMine. These databases also form part of a larger consortium of legume databases known as the Legume Federation (legumefederation.org). The Legume Federation is a joint project with USDA-ARS-Iowa State and the National Center for Genome Resources. Together, these three centers house genomic, genetic and phenotypic (QTL) data for around 10 legume crop species including soybean, common bean, peanut, chickpea, clover, lupin and others. The goal of the project is to provide cross-species links between these plants at the genomic, genetic and phenotypic levels to further legume research and breeding.. ...
White Clover (Trifolium repens) - 04 - Wild Flowers of Sleepy Hollow Lake From All-Creatures.org
The Marshall-Colon Lab » Amy and Katy funded by NSF to study medicago/rhizobia mutualisms!
NSF IOS Award #1645875 Systems genetics of symbiotic quality in legume-rhizobium mutualism.. We are going to build "symbiosis networks" using genomic, transcriptomic, and metabolomic data to determine the molecular underpinnings of high and low partner quality in the medicago/sinorhizobium mutualism.. ...
Medicago truncatula chromosome 6 clone mth2-43g7, WORKING DRAFT SEQUEN - Nucleotide - NCBI
DI-fusion Maturation of nematode-induced galls in Medicago truncatula...
Arabidopsis TAC clones « Experimental Plant Division (RIKEN BRC)
Following manuscript should be referred in the publication on a scientific journal.1. Liu YG, Shirano Y, Fukaki H, Yanai Y, Tasaka M, Tabata S, Shibata D. Complementation of plant mutants with large genomic DNA fragments by atransformation-competent artificial chromosome vector accelerates positionalcloning. Proc Natl Acad Sci U S A. 1999 May 25;96(11):6535-40. PubMed PMID:10339623 ...
Legume Information System
New genome browser for Medicago build 3.5.1. The focus is on relationships with other genomes. Added Medicago truncatula genome build 3.5.1 to Seqqle pages. This supports link-outs to the new Mt GBrowse site (above). Seqqle search reports now include full genome summaries depicting the mapping of query sequences onto the chromosomes of Gm, Lj, and Mt using the new Genome Drawing Engine and the Comparative Map and Trait Viewer.. Read More ». ...
Medicago arborea (Tree Medick) | BioLib.cz
Gene-silencing-induced changes in carbohydrate conformation in relation to bioenergy value and carbohydrate subfractions in...
Gene silencing with RNA interference (RNAi) technology may be capable of modifying internal structure at a molecular level. This structural modification could affect biofunctions in terms of biodegradation, biochemical metabolism, and bioactive compound availability. The objectives of this study were to (1) Detect gene silencing-induced changes in carbohydrate molecular structure in an alfalfa forage (Medicago sativa spp. sativa: alfalfa) with down-regulation of genes that encode transcription factors TT8 and HB12; (2) Determine gene silencing-induced changes in nutrient bioutilization and bioavailability in the alfalfa forage (Medicago sativa); and (3) Quantify the correlation between gene silencing-induced molecular structure changes and the nutrient bioutilization and bioavailability in animals of ruminants. The experimental treatments included: T1 = Non-transgenic and no-gene silenced alfalfa forage (code "NT"); T2 = HB12-RNAi forage with HB12 gene down regulation (code "HB12"); T3 = ...
Dr. Julia Frugoli, Research In My Lab - Clemson University
Untersuchungen zur Funktion de - Titel - sundoc Migration
Farm Journal - White Clover Farm
pewit: May 2009
for the last week Painted Lady butterflies have been everywhere locally with last weekend seeing a strong northerly movement through the area; with light SE winds today another arrival / movement seems to be underway; most of the ones I saw in the week were simply flying by but this morning some were stopping to feed on clover flowers along the Humber bank; most are old and faded / bleached individuals like the lower two but I did come across this brighter / fresher individual early this morning before the sun got too high ...
Nature ID: four-leaf clover ~ 06/30/11 ~ at home
It must be my lucky day, times 2! I never thought about what species of clover the "traditional" four-leaf lucky clover is. Ah, I have many fond memories laying in the warm school yard grass with my girlfriends, searching every recess for those 4 leaves of luck. Looking online for information was entertaining. Heres a "how-to" from wikiHow and its corresponding luck link - numbers 10 and 12 hold especially true for Nature ID. May you have the blessings of luck ...
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به منظور بررسی اثر شبدر ایرانی (Trifolium resupinatum L.) به عنوان گیاه پوششی در کنترل علفهای هرز کلزای پاییزه، آزمایشی بصورت مزرعه ای در قالب طرح بلوک کامل تصادفی با چهار تکرار در سال زراعی 1397-1396 در کیلومتر 35 نهاوند اجرا شد. شش تیمار شامل کاشت کلزای خالص (با و بدون علف هرز) و کلزا همراه با 25، 50، 75 و 100 درصد میزان کشت مطلوب شبدر (50 کیلوگرم در هکتار) به صورت افزایشی بودند. نتایج نشان داد که کاربرد گیاه پوششی اثر معنی داری در کاهش تراکم و وزن خشک علف های هرز در مقایسه با شاهد (تداخل تمام فصل با علف های هرز) دارد. به طوریکه تیمارهای کلزا+25، 50، 75 و 100 درصد تراکم مطلوب شبدر ایرانی ...
Genome sequence of Ensifer meliloti strain WSM1022, a highly effective microsymbiont of the model legume Medicago truncatula...
Ensifer meliloti WSM1022 is an aerobic, motile, Gram-negative, non-spore-forming rod that can exist as a soil saprophyte or as a legume microsymbiont of Medicago. WSM1022 was isolated in 1987 from a nodule recovered from the roots of the annual Medicago orbicularis growing on the Cyclades Island of Naxos in Greece. WSM1022 is highly effective at fixing nitrogen with M. truncatula and other annual species such as M. tornata and M. littoralis and is also highly effective with the perennial M. sativa (alfalfa or lucerne). In common with other characterized E. meliloti strains, WSM1022 will nodulate but fixes poorly with M. polymorpha and M. sphaerocarpos and does not nodulate M. murex. Here we describe the features of E. meliloti WSM1022, together with genome sequence information and its annotation. The 6,649,661 bp high-quality-draft genome is arranged into 121 scaffolds of 125 contigs containing 6,323 protein-coding genes and 75 RNA-only encoding genes, and is one of 100 rhizobial genomes ...
Molecular interactions between medicago truncatula and macrophomina phaseolina
Macrophomina phaseolina is a soil-borne fungal pathogen that causes a disease commonly known as charcoal rot. Currently, there is not an effective method for controlling the disease, because knowledge about the pathogen, the development of the disease and how it interacts with the plant host is limited. Therefore, a study is proposed to investigate the interactions between M. phaseolina and the plant species Medicago truncatula using a molecular genetics approach where the host genes involved in the disease development will be identified. We will first conduct a genetic screen in a mutant population of M. truncatula and look for strains that have altered susceptibility to M. phaseolina. We will then identify the genes that are involved in host-pathogen interactions ...
Medicago Inc. and Mitsubishi Tanabe Pharma Corporation Enter into a Strategic Alliance to Develop New Vaccines | AfricaBusiness...
Medicago to Receive up to $33 Million in Upfront and Milestone Payments as well as Royalties under a First Agreement to Develop a Rotavirus Vaccine QUEBEC CITY, March 6, 2012 /PRNewswire/ - Medicago Inc. (TSX: MDG), a biopharmaceutical company focused on developing highly effective and competitive vaccines based on proprietary manufacturing technologies and Virus-Like Particles (VLPs), today announced the establishment of a strategic alliance with Mitsubishi Tanabe Pharma Corporation (MTPC) through the execution of a Master Research Collaboration Agreement. The objectives are to develop and commercialize at least three new vaccines with MTPC who will provide funding for all research and development costs. In exchange for granting licensing rights, Medicago will be entitled to receive upfront and milestone payments as well as royalties for each product to be developed under this master agreement.. Under this first agreement to develop a Rotavirus Like Particle (RLP) vaccine target, MTPC will have ...
Exploring the nuclear proteome of Medicago truncatula at the switch towards seed filling
Medicago sativa MsPRP2 protein Summary Report | CureHunter
xseA - Exodeoxyribonuclease 7 large subunit - Rhizobium leguminosarum bv. trifolii (strain WSM2304) - xseA gene & protein
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Role of p21ras in growth factor signal transduction | Biochemical Society Transactions
Protein-protein interactions - Institute of Plant Genetics - Leibniz University Hannover
Regulatory networks controling the initiation and development of an arbuscular mycorrhiza (AM) symbiosis involve the interaction of different classes of transcription factors (TFs), primarily belonging to the NF-Y, GRAS, AP2/ERF, and Myb categories. To identify protein-protein interactions amongst selected, AM-activated TFs as well as between those TFs and their target promoters, yeast-2-hybrid (Y2H) and yeast-1-hybrid (Y1H) experiments are performed. To verify such protein-protein interactions in planta, split-YFP fusions of selected, AM-activated TFs are expressed in transgenic Medicago truncatula roots or Nicotiana benthamiana leaves.. ...
Medicago breaks ground on tobacco leaf vaccine facility | Vaccine News
A Tobacco-Based COVID-19 Vaccine? | SFNToday.com
Some might call it an organic approach to fighting COVID 19. A Canadian company is in the final stages of testing a plant-based COVID-19 virus vaccine that they hope can get approval for distribution later this year. Medicago, based near Quebec City, is using chloroplast proteins found in a plant within the tobacco family and native to Australia.. Using plant-chloroplast to create vaccines is not new, as the approach has been used to fight both viral and bacterial diseases. Plant-based virus fighting vaccines include rotavirus in humans and parvovirus in animals. Its bacterial disease vaccines including cholera, Lyme disease, anthrax and tetanus.. Dr. Nathalie Charland, a Medicago with Medicago, says the company is currently in phase three testing of its human trials. She said that, like most of the COVID vaccines already approved, this plant- based vaccine requires two doses, 21 days apart. But she says the Medicago vaccine is inherently different because it does not include COVID 19 genetic ...
User:Marcel Quint/Notebook/medicago/2008 - OpenWetWare
sibboleth --,,div id=y1 style=border:0px;,,div style=display:none; id=id,y1,/div,,div style=display:none; id=dtext,04/23/2008,04/24/2008,04/25/2008,04/26/2008,04/28/2008,04/29/2008,05/05/2008,05/28/2008,05/29/2008,/div,,div style=display:none; id=page,User:Marcel Quint/Notebook/medicago,/div,,div style=display:none; id=fmt,yyyy/MM/dd,/div,,div style=display:none; id=css,OWWNB,/div,,div style=display:none; id=month,1,/div,,div style=display:none; id=year,2008,/div,,div style=display:none; id=readonly,Y,/div,,/div ...
Medicago rugosa images
Author: 'Chen, Rujin' - PubAg Search Results
Plant organs such as seeds are primary sources of food for both humans and animals. Seed size is one of the major agronomic traits that have been selected in crop plants during their domestication. Legume seeds are a major source of dietary proteins and oils. Here, we report a novel and conserved role for BIG SEEDS1 (BS1) gene in the control of seed size and weight in the model legume Medicago tru ...
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Servint. They can also be useful for quick exploration and testing of new components: operating systems, frameworks, software, etc. Simply try us for 30 days risk-free. To clarify the mechanisms of symbiotic cell adaptation to intracellular bacteria, we first quantified cell, vacuole, and microsymbiont surface-volume dynamics during nodule development. ESTs sharing significant identity were also identified in mouse, rat, bovine, and pig databases. Choose a host that uses virtual private servers. Virtual Private Servers from Knownhost give you the flexibility, security and performance you need to run your website with added peace of mind. Web hosting accounting software, the mechanisms that enable the opportunistic fungus to become pathogenic have not been revealed yet. Your data is stored on access protected storage networks and is always available even if one storage node fails. If you need hosting for a short time periodвsay, less than a month or twoвyoull typically receive a refund should ...
Lobbying Spending Database - Medicago, 2017 | OpenSecrets
White clover | Pasture Improvement Initiative
Specimen Code: CUP-LP-000265; Determined By: J.F. Babcock; Date Determined: Sep 22,1999; Slant: no; -80° C Freezer: no; Herbarium: CCFB; d H2O: n/a; Collected By: J.F. Babcock; Date(s) Collected: 20 Sep 1999; Soil type: HdD; Source: on dead wood; Locality Code: Sector 8; Locality Name: Lindsay-Parsons Biodiversity Preserve; Township: West Danby, Tompkins Co.; State: NY; Country: USA; Elevation: 950 ft.-1050 ft.; Loc Latitude: 42°1853N; Loc Longitude: 76°3043W ...
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euskara | Txantxangorria-Euskal karaokeak - Part 2
Karaoke hau ahotsarekin: https://www.youtube.com/watch?v=t3pNc669RJk Nork esan du, ezinezkoa da? Nork onartu du,hori hala dela? Zaila bada,ez da ezinezkoa, zaila bada,badago lortzea Eta eroriz ikasten bada oinez has gaitezen bidea egiten. Ez gaitu inork geldituko Ez gaitu inork geldituko Nork esan du, ez dago lortzerik? Nork esan du, ez dut gaitasunik?… Read more"Ez gaitu inork geldituko (URTZ) Ahotsbakoa". ...
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Trifolium -- Discover Life
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List of the vascular plants in the Red Data Book of Russia
Sown Biodiverse Pastures
This mutualism has been observed with many plant species, including Medicago polymorpha and Medicago truncatula plants from ... S.medicae was first isolated from root nodules on plants in the Medicago genus. Some strains of S.medicae, like WSM419, are ... Because S. medicae associates well with plants in the Medicago genus and increases plants growth, crop fields are commonly ... nov., isolated from annual Medicago spp". International Journal of Systemic Bacteriology: 972-980. "Sinorhizobium medicae ...
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He XZ, Reddy JT, Dixon RA (1998). "Stress responses in alfalfa (Medicago sativa L). XXII. cDNA cloning and characterization of ... Medicago sativa L.)". Arch. Biochem. Biophys. 336 (1): 121-9. doi:10.1006/abbi.1996.0539. PMID 8951042. ... "Isoflavone O-methyltransferase activities in elicitor-treated cell suspension cultures of Medicago sativa". Phytochemistry. 30 ...
Dakora, F. D., Joseph, C. M., & D. A. Phillips (1993). "Alfalfa (Medicago sativa L.) Root Exudates Contain Isoflavonoids in the ... 2006). "Nitrogen-fixing sinorhizobia with Medicago laciniata constitute a novel biovar (bv. medicaginis) of S. meliloti". Syst ... 2004). "The effect of rhizobiophages on Sinorhizobium meliloti-Medicago sativa symbiosis". Biology and Fertility of Soils. 39 ( ... rigiduloides, among Ensifer meliloti efficiently nodulating Medicago species". Syst. Appl. Microbiol. 36 (7): 490-6. doi: ...
Medicago) and rarely palmately compound (e.g. Lupinus), in the Mimosoideae and the Caesalpinioideae commonly bipinnate (e.g. ... Recruitment of Medicago floral pectic genes for symbiosis". The Plant Journal. 39 (4): 587-98. doi:10.1111/j.1365-313X. ... Medicago sativa (alfalfa), Arachis hypogaea (peanut), Ceratonia siliqua (carob), and Glycyrrhiza glabra (liquorice). A number ...
Medicago intertexta - Wikimedia Commons
... easily hybridizes with Medicago falcata (which is sometimes treated as a subspecies of M. sativa). Most newer ... Medicago sativa L.. Fabaceae. Alfalfa, Lucerne. Source: James A. Duke. 1983. Handbook of Energy Crops. unpublished. *Uses *Folk ... Green forage of Medicago sativa is reported to contain per 100 g, 80.0% moisture, 5.2 g protein, 0.9 g fat, 3.5 g fiber, and ... The genus Medicago has been reported to contain the following chemicals, relative toxicities of which are tabulated in Dukes " ...
Medicago - Wikipedia
Medicago laxispira Heyn Medicago minima (L.) Bart. Medicago polymorpha L. Medicago praecox DC. Medicago sauvagei Nègre Medicago ... Medicago huberi E. Small Medicago rostrata (Boiss. & Bal.) E. Small Medicago lupulina L. Medicago secundiflora Durieu Medicago ... Medicago italica (Miller) Fiori Medicago lesinsii E. Small Medicago littoralis Rohde ex Lois. Medicago murex Willd. Medicago ... Medicago noeana Boiss. Medicago rugosa Desr. Medicago rotata Boiss. Medicago scutellata (L.) Miller Medicago shepardii Post ...
annexin D1 [Medicago truncatula] - Protein - NCBI
Lobbying Spending Database - Medicago, 2017 | OpenSecrets
Medicago noeana - Wikipedia
Genome-Wide Medicago truncatula Small RNA Analysis Revealed Novel MicroRNAs and Isoforms Differentially Regulated in Roots and...
Genome-Wide Medicago truncatula Small RNA Analysis Revealed Novel MicroRNAs and Isoforms Differentially Regulated in Roots and ... Genome-Wide Medicago truncatula Small RNA Analysis Revealed Novel MicroRNAs and Isoforms Differentially Regulated in Roots and ... Genome-Wide Medicago truncatula Small RNA Analysis Revealed Novel MicroRNAs and Isoforms Differentially Regulated in Roots and ... Genome-Wide Medicago truncatula Small RNA Analysis Revealed Novel MicroRNAs and Isoforms Differentially Regulated in Roots and ...
Medicago -- Discover Life
Medicago. Life Plantae Dicotyledoneae Fabaceae © Copyright Malcolm Storey 2011-2118 · 6. Medicago minima. Click on map for ... Medicago lupulina, Black medic. © Copyright Malcolm Storey 2011-2118 · 5. Medicago minima. © Copyright Malcolm Storey 2011-2118 ... Medicago polymorpha. © Copyright Malcolm Storey 2011-2118 · 3. Medicago lupulina. © Copyright Malcolm Storey 2011-2118 · 3. ... Medicago lupulina. © Copyright Malcolm Storey 2011-2118 · 3. Medicago lupulina. © Copyright Malcolm Storey 2011-2118 · 3. ...
myb-like protein A [Medicago truncatula] - Protein - NCBI
Functional Genomics in Medicago truncatula | SpringerLink
This volume discusses popular methods to achieve different types of mutagenesis and forward/reverse genetics in Medicago ... Cutting-edge and thorough, Functional Genomics in Medicago truncatula: Methods and Protocols is a valuable resource for anyone ... Targeting Induced Local Lesions IN Genomes (TILLING) in Medicago truncatula Myriam Sánchez, Christine Le Signor, Gregoire ... Stable Inactivation of MicroRNAs in Medicago truncatula Roots Hélène Proust, Jérémie Bazin, Céline Sorin, Caroline Hartmann, ...
Plants Profile for Medicago polymorpha (burclover)
The Multiple Faces of the Medicago-Sinorhizobium Symbiosis | SpringerLink
Medicago truncatula is able to perform a symbiotic association with Sinorhizobiumspp. This interaction leads to the formation ... A molecular view on nodule senescence in Medicago truncatula. Plant Physiol 141:711-720PubMedPubMedCentralCrossRefGoogle ... Medicago-Sinorhizobium Symbiosis Symbiotic genes Nitrogen fixation This is a preview of subscription content, log in to check ... Medicago truncatula is able to perform a symbiotic association with Sinorhizobium spp. This interaction leads to the formation ...
Plants Profile for Medicago lupulina (black medick)
Medicago phrygia - Wikispecies
Medicago falcata - definition of Medicago falcata by The Free Dictionary
Medicago falcata synonyms, Medicago falcata pronunciation, Medicago falcata translation, English dictionary definition of ... Noun 1. Medicago falcata - European medic naturalized in North America having yellow flowers and sickle-shaped pods sickle ... Medicago falcata. Also found in: Thesaurus, Wikipedia.. Related to Medicago falcata: Medicago lupulina, Medicago sativa ... Medicago falcata - definition of Medicago falcata by The Free Dictionary https://www.thefreedictionary.com/Medicago+falcata ...
Medicago] publications using Medicago genome info
... medicago from net.bio.net via medicago%40net.bio.net (by medicago from net. ... More information about the Medicago mailing list. Send comments to us at biosci-help [At] net.bio.net ... Greetings We are trying to compile a list of publications that have made use of the Medicago genome sequence. If you made use ...
Physiological, Cytological and Biochemical Stability of Medicago ...: Ingenta Connect
Medicago] 24th Stadler Symposium Genomics of Disease
Medicago truncatula Genome Project :: Mutant Information :: References
Isolation of Medicago truncatula Mutants Defective in Calcium Oxalate Crystal Formation. Plant Physiol. 2000; 124:1097-1104.[ ... The NFP locus of Medicago truncatula controls an early step of Nod factor signal transduction upstream of a rapid calcium flux ... nip, a Symbiotic Medicago truncatula Mutant that Forms Root Nodules with Aberrant Infection Threads and Plant Defense-Like ... Isolation and characterization of diverse developmental mutants in Medicago truncatula.. Plant Physiol. 2000; 123:1387-1397.[ ...
Browse Products Containing: MEDICAGO SATIVA (ALFALFA) EXTRACT || Skin Deep® Cosmetics Database | EWG
Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWGs strict health criteria. Before a company can use EWG VERIFIEDTM on such products, the company must show that it fully discloses the products ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED member companies that help to support the important work we do. Learn more , Legal Disclaimer ...
Medicago truncatula Genome Database | J. Craig Venter Institute
Medicago truncatula Genome Database. Medicago truncatula, a close relative of alfalfa, is a preeminent model for the study of ... The Medicago Genome DataBase and Legume Data Federation. JCVI hosts the M. truncatula genome sequence and annotation in three ... A community resource for high-throughput quantitative RT-PCR analysis of transcription factor gene expression in Medicago ... Databases and information integration for the Medicago truncatula genome and transcriptome.. Plant physiology. 2005-05-01; ...
Medicago sativa Alfalfa, Yellow alfalfa PFAF Plant Database
Medicago sativa is a PERENNIAL growing to 1 m (3ft 3in) at a medium rate. It is hardy to zone (UK) 5. It is in flower from June ... Medicago sativa is a PERENNIAL growing to 1 m (3ft 3in) at a medium rate. It is hardy to zone (UK) 5. It is in flower from June ... Medicago polymorpha. Toothed Bur-Clover, Burclover. Annual. 0.6. 0-0 LM. N. DM. 2. 0. 0. ... Medicago lupulina. Black Medick. Annual/Perennial. 0.5. 4-8 M. LMH. N. M. 2. 1. 0. ...
The Model Legume Medicago truncatula | Molecular Microbiology | Microbiology & Virology | Life Sciences | Subjects | Wiley
The Model Legume Medicago truncatula starts with an examination of M. truncatula plant development; biosynthesis of natural ... Symbiosis of Medicago truncatula with arbuscular mycorrhiza comes next, followed by chapters on the common symbiotic signaling ... This reference provides comprehensive coverage of the Model Legume Medicago truncatula. It features review chapters as well as ... and genomics of Medicago truncatula Model plant species are valuable not only because they lead to discoveries in basic biology ...
The Model Legume Medicago truncatula | Molecular Microbiology | Microbiology & Virology | Life Sciences | Subjects | Wiley
Medicago-Aphid interactions. Karam Singh, Lars Kamphuis plus Glen Powell. 126.96.36.199. Medicago truncatula-pea aphid interaction in ... Saponins in Medicago truncatula: structures and activities. Pedro Da Silva. 4.3. Saponin synthesis in Medicago truncatula ... Medicago truncatula and other annual Medicago spp.- interactions with root and foliar, oomycete and viral pathogens. M. ... A Snapshot of Functional Genetic Studies in Medicago truncatula. Jerome Verdier. 2.2. Medicago truncatula as an ecological, ...
IFR - Isoflavone reductase - Medicago sativa (Alfalfa) - IFR gene & protein
"Crystal structure of isoflavone reductase from alfalfa (Medicago sativa L.).". Wang X., He X., Lin J., Shao H., Chang Z., Dixon ... "Crystal structure of isoflavone reductase from alfalfa (Medicago sativa L.).". Wang X., He X., Lin J., Shao H., Chang Z., Dixon ... "Crystal structure of isoflavone reductase from alfalfa (Medicago sativa L.).". Wang X., He X., Lin J., Shao H., Chang Z., Dixon ... "Crystal structure of isoflavone reductase from alfalfa (Medicago sativa L.).". Wang X., He X., Lin J., Shao H., Chang Z., Dixon ...
11441433 - Annexin - Medicago truncatula (Barrel medic) - 11441433 gene & protein
Medicago's Innovative Vaccine Production Using Tobacco Plants
Mitsubishi Tanabe Pharma (MTP) purchased 60 percent of Medicago in September 2013, delisting Medicagos stock and leaving the ... Medicagos Innovative Vaccine Production Using Tobacco Plants. Source: Life Science Leader Contact The Supplier By Wayne ... Medicagos story recalls how biotech first got started: mainly as a manufacturing alternative, only then with E. coli or yeast ... Because Medicago is building a new, plant-based technology, it finds itself in a leadership position, compared to companies in ...
Medicago | definition of Medicago by Medical dictionary
Medicago explanation free. What is Medicago? Meaning of Medicago medical term. What does Medicago mean? ... Looking for online definition of Medicago in the Medical Dictionary? ... Related to Medicago: Medicago sativa, Medicago lupulina. Medicago. plant genus of the legume family Fabaceae; contains ... Medicago will also fund the development of additional potential product candidates.. Medicago finalises CAD25m private ...
MsPG3, a Medicago sativa polygalacturonase gene expressed during the alfalfa-Rhizobium meliloti interaction | PNAS
Medicago PGs and the control Msc27 sequences were coamplified during 25 cycles from RNA of various plant tissues of M. sativa ... To estimate the number of PG genes in Medicago, genomic DNA from the diploid M. truncatula was digested with EcoRI and HindIII ... MsPG3, a Medicago sativa polygalacturonase gene expressed during the alfalfa-Rhizobium meliloti interaction. Jose A. Muñoz, ... Southern blot analysis of Medicago plants. M. truncatula genomic DNA was digested with EcoRI (E) and HindIII (H) and hybridized ...
Medicago announces technological milestone with production of self-assembled Influenza Virus-Like
... Particles in plants
. ... About Medicago Medicago is a biotechnology company focused on the development, production and commercialization of vaccines and ... Louis Vezina, Chief Scientific Officer of Medicago. "This is an excellent result and a major milestone for Medicago," said Andy ... Medicago announces technological milestone with production of self-assembled Influenza Virus-Like Particles in plants. ...
. ... About Medicago Medicago is a biotechnology company focused on the development, production and commercialization of vaccines and ... Louis Vezina, Chief Scientific Officer of Medicago. "This is an excellent result and a major milestone for Medicago," said Andy ... Medicago announces technological milestone with production of self-assembled Influenza Virus-Like Particles in plants. ...
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- Other than alfalfa, several of the creeping members of the family (such as Medicago lupulina and Medicago truncatula) have been used as forage crops. (wikipedia.org)
- Medicago rupestris M. Bieb Medicago sativa L. (alfalfa) M. s. caerulea M. s. falcata (Medicago falcata) M. s. f. var. (wikipedia.org)
- Medicago falcata is a yellow flowered perennial alfalfa that is native to Siberia. (thefreedictionary.com)
- Medicago truncatula , a close relative of alfalfa, is a preeminent model for the study of the processes of nitrogen fixation, symbiosis, and legume genomics. (jcvi.org)
- Stress responses in alfalfa (Medicago sativa L.) 11. (uniprot.org)
- Phytofiltration of hazardous cadmium, chromium, lead and zinc ions by biomass of Medicago sativa (Alfalfa). (thefreedictionary.com)
- Caracterizacion y valor biologico en ratas desnutridas, del extracto foliar seco obtenido de alfalfa Medicago sativa cultivada en el Peru [resumen]. (thefreedictionary.com)
- Medicago is derived from Medike, or medick, the Greek name for alfalfa, which came to Greece from Medea, while lupulina means hop-like. (vplants.org)
- The genus Medicago , a member of the legume (Fabaceae) family, comprises 87 species of flowering plants, including the forage crop M. sativa (alfalfa) and the model legume M. truncatula (barrel medic). (rsc.org)
- Alfalfa ( Medicago sativa ) is native to Iran and was likely domesticated during the Bronze Age to feed horses arriving from Central Asia. (highlighthealth.com)
- Nucleotide polymorphism of the Srlk gene that determines salt stress tolerance in alfalfa ( Medicago sativa L. (springer.com)
- Based on legume genome syntheny, the nucleotide sequence of Srlk gene, key role of which in response to salt stress was demonstrated for the model species Medicago truncatula , was identified in the major forage and siderate crop alfalfa ( Medicago sativa ). (springer.com)
- An alfalfa ( Medicago sativa ) association panel comprised of 336 genotypes from 75 alfalfa accessions represented by four to eight genotypes for each accession. (frontiersin.org)
- Alfalfa ( Medicago sativa ) is one of the most important forage crops in the world due to its high biomass and choice nutritional profiles and it provides reliable sources of protein and minerals to animals. (frontiersin.org)
- Alfalfa ( Medicago sativa L. ) is a widely grown perennial herbaceous legume (Lesins and Lesins, 1979) that is a tetraploid (2n = 4x = 32). (agr.ca)
- This Decision Document has been prepared to explain the regulatory decisions reached under Directive 94-08 (Dir94-08) - Assessment Criteria for Determining Environmental Safety of Plants with Novel Traits, its companion document BIO2005-02 - The Biology of Medicago sativa L. (alfalfa) and Section 2.6 - Guidelines for the Assessment of Novel Feeds: Plant Sources, of Chapter 2 of the RG-1 Regulatory Guidance: Feed Registration Procedures and Labelling Standards. (gc.ca)
- Monsanto Canada Inc. and Forage Genetics International have developed an alfalfa ( Medicago sativa L. ) event with reduced lignin compared to conventional alfalfa at the same stage of growth. (gc.ca)
- Although previous reports showed that nolR modulates Nod-factor production and enhances nodulation speed of Sinorhizobium meliloti on alfalfa, there have been no reports for the symbiotic function of this gene in the S. medicae-Medicago truncatula symbiosis. (apsnet.org)
- Recently, genetically modified alfalfa (Medicago sativa) varieties have been marketed with reduced lignin and improved forage quality traits, including increased digestibility by ruminants at later stages of plant maturity. (umn.edu)
- dehydrin genes from alfalfa (Medicago sativa spp. (gc.ca)
- The objectives of this study were to (1) Detect gene silencing-induced changes in carbohydrate molecular structure in an alfalfa forage ( Medicago sativa spp. (gc.ca)
- Effect of tillage on nitrogen response in corn (Zea mays L.) after established alfalfa (Medicago sativa L. (eurekamag.com)
- Alfalfa (Medicago sativa), also known as lucerne is used for boosting energy levels as well as helping with menopause. (ageless.co.za)
- The use of herbal remedies, including the herb alfalfa (also known as lucerne), classified as Medicago sativa, are popular as an alternative to standard Western allopathic medicine for a variety of problems, including menopause , alcoholism , drug dependency as well as boosting energy levels . (ageless.co.za)
- Four linkage groups representing the four haplotypes of each alfalfa chromosome were assigned to each of the eight Medicago chromosomes in both the maternal and paternal parents. (g3journal.org)
- Phoma medicaginis is the causal agent of spring black stem and leaf spot in alfalfa ( Medicago sativa ), a major fodder and forage crop in temperate and Mediterranean regions. (biomedcentral.com)
- Medicago is a genus of flowering plants, commonly known as medick or burclover, in the legume (Fabaceae) family. (wikipedia.org)
- The species Medicago truncatula is a model legume due to its relatively small stature, small genome (450-500 Mbp), short generation time (about 3 months), and ability to reproduce both by outcrossing and selfing. (wikipedia.org)
- An improved genome release (version Mt4.0) for the model legume Medicago truncatula. (jcvi.org)
- This reference provides comprehensive coverage of the Model Legume Medicago truncatula. (wiley.com)
- Symbiosis of Medicago truncatula with arbuscular mycorrhiza comes next, followed by chapters on the common symbiotic signaling pathway (CSSP or SYM) and infection events in the Rhizobium-legume symbiosis. (wiley.com)
- The Model Legume Medicago truncatula is an excellent book for researchers and upper level graduate students in microbial ecology, environmental microbiology, plant genetics and biochemistry. (wiley.com)
- GeneChip Medicago Transcriptome Solution is the fastest and most effective whole transcriptome profiling approach for legume researchers who want results within a crop season. (thermofisher.com)
- The Auxin Response Factor (ARF) family of transcription factors is an important regulator of environmental response and symbiotic nodulation in the legume Medicago truncatula . (frontiersin.org)
- The diploid annual legume Medicago truncatula has been developed as a tractable genetic system for studying biological questions that are unique to, or well suited for study in legume species. (plantphysiol.org)
- Previous studies exploring sequence variation in the model legume, Medicago truncatula, relied on mapping short reads to a single reference. (nih.gov)
- Here, the structural characterization of two glutamine synthetase isoforms from the model legume Medicago truncatula is reported: the crystallographic structure of cytoplasmic GSII-1a and an electron cryomicroscopy reconstruction of plastid-located GSII-2a. (iucr.org)
- Here, we used direct and indirect ethylene application and inhibition of ethylene biosynthesis, together with comparison of wild-type plants and an ethylene-insensitive supernodulating mutant, to assess the effect of ethylene at multiple stages of this interaction in the model legume Medicago truncatula . (plantcell.org)
- A two-dimensional electrophoresis proteomic reference map and systematic identification of 1367 proteins from a cell suspension culture of the model legume Medicago truncatula. (semanticscholar.org)
- In the model legume Medicago truncatula, iron is delivered by the vasculature and released in the apoplast on the zone II of the nodule (infection/maturation zone). (upm.es)
- In this work, we structurally characterize the ACAULIS5 gene product, TSPS, from the model legume plant Medicago truncatula ( Mt ). Six crystal structures of Mt TSPS-one without ligands and five in complexes with either reaction substrate (SPD), reaction product (TSPM), or one of three cofactor analogues (5'-methylthioadenosine, S-adenosylthiopropylamine, and adenosine)-give detailed insights into the biosynthesis of TSPM. (biochemj.org)
- Therefore, Medicago truncatula, which has a relatively small diploid genome, has been adopted as a model species for legume genomics. (deepdyve.com)
- The aim of this work was to integrate the genetic map of Arachis with Lotus and Medicago and improve our understanding of the Arachis genome and legume genomes in general. (biomedcentral.com)
- The Arachis and model legume genomes comparison made here, together with a previously published comparison of Lotus and Medicago allowed all possible Arachis-Lotus-Medicago species by species comparisons to be made and genome syntenies observed. (biomedcentral.com)
- Effects of replacing lucerne (Medicago sativa L.) hay with fresh citrus pulp on ruminal fermentation and ewe performance. (thefreelibrary.com)
- 2009) the energy and protein values of lucerne ( Medicago sativa L.) hay in South Africa could vary considerably and should be determined beforehand in order to accurately compose a balanced diet. (scielo.org.za)
- Six hundred lucerne ( Medicago sativa L.) hay samples were collected from several commercial irrigation farms in the main lucerne producing areas in South Africa, which varied in location, soil characteristics (texture, organic matter, N content, pH) and farm management. (scielo.org.za)
- Lucerne (Medicago sativa L.) has a considerable amount of genetic diversity for many agronomic and physiological traits. (edu.au)
- The establishment and growth of 'Stamina 5' lucerne (Medicago sativa) seed sown with three inoculant carriers (ALOSCA®, coated, and peat slurry treated) or as bare seed (control) on five dates (21 October 2010, 9 November 2010, 8 December 2010, 13 January 2011 and 3 February 2011) was investigated on a Lismore stony silt loam soil at Ashley Dene dryland research farm in Canterbury. (lincoln.ac.nz)
- Medicago species are used as food plants by the larvae of some Lepidoptera species including the common swift, flame, latticed heath, lime-speck pug, nutmeg, setaceous Hebrew character, and turnip moths and case-bearers of the genus Coleophora, including C. frischella (recorded on M. sativa) and C. fuscociliella (feeds exclusively on Medicago spp. (wikipedia.org)
- Medicago noeana is a plant species of the genus Medicago. (wikipedia.org)
- Genus Medicago with five (5) species and three (3) varieties were dominant with respect to other three genera in this tribe. (thefreedictionary.com)
- Finally, we give an overview of the advances made in metabolic engineering in Medicago species and how the development of novel molecular and omics toolkits can influence a better understanding of this genus in terms of specialized metabolism and chemistry. (rsc.org)
- Lesins K.A., Lesins I. (1979) Genus Medicago and Key to Subgenera. (springer.com)
- In: Genus Medicago (Leguminosae). (springer.com)
- 2005) constructed a molecular phylogeny of 23 Sinorhizobium strains and tested the symbiotic ability of six strains with 35 Medicago species. (wikipedia.org)
- Furthermore, they propose that the geographical distribution of strains limits the distribution of particular Medicago species. (wikipedia.org)
- Medicago species synthesize a variety of bioactive natural products that are used to engage into symbiotic interactions but also serve to deter pathogens and herbivores. (rsc.org)
- In this review, we focus on the two most interesting and well characterized secondary metabolite classes found in Medicago species, the triterpene saponins and the flavonoids, with a detailed overview of their biosynthesis, regulation, and profiling methods. (rsc.org)
- It is intended to provide background information on the biology of Medicago sativa L. , its centre of origin, its related species and the potential for gene introgression from M. sativa L. into relatives, and details of the life forms with which it may interact. (agr.ca)
- For more information on this plant species, see Hank's page on Medicago polymorpha (opens in a new tab). (cabezaprieta.org)
- Blondon F, Marie D, Brown S, Kondorosi A (1994) Genome size and base composition in Medicago sativa and M. truncatula species. (springer.com)
- Comparative transcriptome analysis of Medicago versus Arabidopsis revealed significant divergence in developmental expression profiles of orthologous genes, which indicates that phylogenetic analysis alone is insufficient to predict the function of orthologs in different species. (deepdyve.com)
- Background: Saponins from Medicago species display several biological activities, among them apoptotic effects against plant cells have been evidenced. (eurekaselect.com)
- Objective: To explore the cytotoxic properties of saponin from Medicago species against animal cells and their effect in combination with the antitumoral drug cisplatin. (eurekaselect.com)
- Moreover saponins from Medicago species have evidenced interesting properties to mediate cisplatin effects in tumor cell lines. (eurekaselect.com)
- By Northern blot, MsPG3 transcripts are not detected in various Medicago tissues, indicating that the function of this gene is related closely to symbiosis. (pnas.org)
- The plant genetic components required for this symbiosis are being identified by analysis of the model legumes Lotus japonicus and Medicago truncatula . (plantcell.org)
- E. Small Medicago lupulina L. Medicago secundiflora Durieu Medicago cancellata M. Bieb. (wikipedia.org)
- Medicago lupulina L. (usda.gov)
- The Plants Database includes the following 1 subspecies of Medicago lupulina . (usda.gov)
- The range of Medicago lupulina covers Europe, North Africa and West and South Asia. (thefreedictionary.com)
Chief Executive Officer o2
- This is an excellent result and a major milestone for Medicago," said Andy Sheldon, President and Chief Executive Officer of Medicago. (newswire.ca)
- It is very gratifying to see that our technology is again being recognized as innovative in our industry", said Bruce Clark , President & Chief Executive Officer of Medicago. (biospace.com)
- In legumes like the model Medicago truncatula , roots are able to develop a de novo meristem through the symbiotic interaction with nitrogen-fixing rhizobia. (plantcell.org)
- Although the legumes included in our study, Lotus japonicus , Medicago truncatula , bean, and Arachis are all in the Papilionoideae subfamily, they belong to three different clades: halogalegina, phaseoloid/millettioid, and aeschynomenoid/dalbergioid. (genetics.org)
- Medicago truncatula and Lotus japonicus are considered as model legumes for the research on indeterminate en determinate nodule formation and development respectively. (ugent.be)
- The Galegoids are mostly temperate and include clover, fava bean and the model legumes Lotus and Medicago (both with substantially sequenced genomes). (biomedcentral.com)
- Note that Arachis which is a member of the Dalbergioids, represents a more basally diverged Papilionoid than the Galegoid legumes, and therefore serves as an out-group to a Lotus vs. Medicago comparison. (biomedcentral.com)
- van Noorden GE, Verbeek R, Dinh QD, Jin J, Green A, Ng JLP, Mathesius U. Molecular Signals Controlling the Inhibition of Nodulation by Nitrate in Medicago truncatula . (mdpi.com)
- Moreover, the nodulation phenotype of the nolR mutant differed among Medicago genotypes and showed significantly enhanced nodule development on M. tricycla . (apsnet.org)
- In this study, the role of three transcription factors in nodulation and other plant developmental pathways was investigated in Medicago truncatula. (ugent.be)
- RESULTS: We screened a core collection of Medicago truncatula genotypes with several strains of Sinorhizobium meliloti and identified a naturally occurring dominant gene that restricts nodulation by S. meliloti Rm41. (uky.edu)
- CLE peptide tri-arabinosylation and peptide domain sequence composition are essential for SUNN-dependent autoregulation of nodulation in Medicago truncatula. (auckland.ac.nz)
- MtCLE12 and MtCLE13 encode CLAVATA3/EMBRYO-SURROUNDING REGION RELATED (CLE) peptides which regulate autoregulation of nodulation (AON) in Medicago through the shoot receptor, SUNN (SUPER NUMERIC NODULES). (auckland.ac.nz)
- Identification of four genes of Medicago truncatula controlling steps in Nod factor transduction. (jcvi.org)
- Since January 2012, research conducted by Medicago and Cellectis plant sciences has demonstrated high levels of efficacy using Cellectis' nucleases to modify six different genes in the tobacco genome related to protein glycosylation. (thefreedictionary.com)
- We have identified two classes of cDNA fragments corresponding to two classes of PG genes in the Medicago genome. (pnas.org)
- Fig. S4 Relative expression of selected genes in untreated Medicago truncatula roots. (wiley.com)
- Green forage of Medicago sativa is reported to contain per 100 g, 80.0% moisture, 5.2 g protein, 0.9 g fat, 3.5 g fiber, and 2.4 g ash. (purdue.edu)
- About Medicago Medicago is a biotechnology company focused on the development, production and commercialization of vaccines and therapeutic protein-based biopharmaceuticals using a proprietary manufacturing system developed from its expertise in the genetic engineering of plants. (newswire.ca)
- In another related agreement, Medicago licensed a portfolio of plant-based protein development technologies from Philip Morris. (fiercepharma.com)
- Fig. S3 HyPer protein production in composite plants of Medicago truncatula . (wiley.com)
- The LATD gene of Medicago truncatula is required for both nodule and root development. (jcvi.org)
- A community resource for high-throughput quantitative RT-PCR analysis of transcription factor gene expression in Medicago truncatula. (jcvi.org)
- We showed that MsPG3 is a single gene in the Medicago genome coding for PG. (pnas.org)
- Gene-silencing-induced changes in carbohydrate conformation in relation to bioenergy value and carbohydrate subfractions in modeled plant ( Medicago sativa ) with Down-Regulation of HB12 and TT8 transcription factors. (gc.ca)
- Identification of a Dominant Gene in Medicago truncatula That Restrict" by Jinge Liu, Shengming Yang et al. (uky.edu)
- Medicago polymorpha L. Medicago praecox DC. (wikipedia.org)
- Medicago polymorpha L. (usda.gov)
- Medicago polymorpha L. f. apiculata (Willd. (usda.gov)
- This name is unresolved , but some data suggest that it is synonymous with Medica hirsuta (L.) Bubani , but some data suggest that it is an infraspecific name of Medicago polymorpha L. . (theplantlist.org)
- It is possible the same name was included from a different data source, to check this you can search for Medicago polymorpha in version 1 of The Plant List . (theplantlist.org)
- Medicago truncatula is able to perform a symbiotic association with Sinorhizobium spp. (springer.com)
- Jones KM, Kobayashi H, Davies BW, Taga ME, Walker GC (2007) How rhizobial symbionts invade plants: the Sinorhizobium-Medicago model. (springer.com)
- Biochemical and Molecular Phylogenetic Study of Agriculturally Useful Association of a Nitrogen-Fixing Cyanobacterium and Nodule Sinorhizobium with Medicago sativa L. (hindawi.com)
- However, the lack of a T3SS in many sequenced S. meliloti strains raises the question of how the specificity is regulated in the Medicago-Sinorhizobium system beyond Nod-factor perception. (uky.edu)
- This rapid time frame is critical as it could allow the vaccination of a population before the first wave of the pandemic strikes," said Andy Sheldon, President and CEO of Medicago. (newswire.ca)
- This trial was the first ever clinical evaluation of a plant-based Influenza VLP vaccine and shows that Medicago's vaccine is safe in humans," said Andy Sheldon, President and CEO of Medicago. (presseportal.de)
- These additional data expand upon the results we announced in June and support our belief that our influenza vaccines are also capable of providing protection against different circulating viral strains," said Andy Sheldon, President and CEO of Medicago. (bio-medicine.org)
- Andy Sheldon, the president and CEO of Medicago, told HeraldSun.com that the company plans to tap into the $7 billion pandemic and seasonal flu vaccine markets. (vaccinenewsdaily.com)
- Our transient expression system which produces recombinant vaccine antigens in the cells of non-transgenic plants has demonstrated its efficiency and medical potential by successfully producing the H5N1 Avian Influenza vaccine candidate in VLPs," said Dr. Louis Vezina, Chief Scientific Officer of Medicago. (newswire.ca)
- WASHINGTON, D.C. , April 25, 2019 /PRNewswire/ - Medicago , a Canadian biotech company and global leader in the development and production of plant-derived vaccines, announced today that its proprietary plant-based production platform, Proficia® was named "Best New Vaccine Technology/platform" at the World Vaccine Congress in Washington, D.C. , attended by 1,500 participants including key opinion leaders from the vaccine industry. (biospace.com)
- QUEBEC CITY, July 15 /CNW/ - Medicago Inc. (TSX-V: MDG) today announced that it will conduct a feasibility study in collaboration with Genopole biopark, in Evry, for the establishment of a vaccine production facility in France. (newswire.ca)
- Medicago is developing VLP vaccines to protect against H5N1 pandemic influenza, using a transient expression system which produces recombinant vaccine antigens in non-transgenic plants. (newswire.ca)
- Results at these lower dosage levels have not been reported for an H5N1 vaccine manufactured with a novel vaccine manufacturing technology," said Nathalie Landry, VP Product Development of Medicago. (presseportal.de)
- Biopharmaceutical firm Medicago has produced a Virus-Like Particle (VLP) of the novel coronavirus, SARS-CoV-2, marking the first step in COVID-19 vaccine development. (pharmaceutical-technology.com)
- Medicago CEO Dr Bruce Clark said: "The pace of our initial progress in Covid-19 is attributable to the capability of our plant-based platform, which is able to produce vaccine and antibody solutions to counteract this global public health threat. (pharmaceutical-technology.com)
- Medicago, a biopharmaceutical company headquartered in Quebec City, and GlaxoSmithKline (GSK) are pleased to announce the start of Phase 3 clinical testing of Medicago's plant-derived COVID-19 vaccine candidate in combination with GSK's pandemic adjuvant, as part of the ongoing Phase 2/3 study. (gsk.com)
- The FDA's decision to grant Fast Track designation for Medicago's vaccine candidate will help us expedite our efforts to bring the first plant-derived COVID-19 vaccine to market, subject to regulatory approval," said Carolyn Finkle, Chief Operating Officer of Medicago. (gsk.com)
- QUEBEC CITY July 30 / Medicago Inc. (TSX-V: MD...Medicago's H1N1 VLP vaccine was formulated to protect against the infl. (bio-medicine.org)
- QUEBEC CITY, July 30 /PRNewswire-FirstCall/ - Medicago Inc. (TSX-V: MDG) a biotechnology company focused on developing highly effective and affordable vaccines based on proprietary manufacturing technologies and Virus-Like Particles (VLPs), today announced that it has achieved additional positive results with its vaccine candidate for the Influenza A (H1N1) virus, also known as Swine flu. (bio-medicine.org)
- In a continuation of this study, Medicago tested the immune response of its H1N1 vaccine against the California/07 virus, a more current and mutated strain and showed positive immune response after a single dose of 5 micrograms. (bio-medicine.org)
- The Medicago truncatula Genome Sequencing Website (N.D. Young, et al. (noble.org)
- Databases and information integration for the Medicago truncatula genome and transcriptome. (semanticscholar.org)
- Chromosome assignments were made based on homology of markers to the Medicago truncatula genome. (g3journal.org)
- citation needed] This list is compiled from: Medicago retrorsa (Boiss. (wikipedia.org)
- E. Small Medicago crassipes (Boiss. (wikipedia.org)
- Medicago halophila (Boiss. (wikipedia.org)
- E. Small Medicago heldreichii (Boiss. (wikipedia.org)
- Sirjaev) E. Small Medicago persica (Boiss. (wikipedia.org)
- Medicago rigida (Boiss. (wikipedia.org)
- E. Small Medicago rhytidiocarpa (Boiss. (wikipedia.org)
- Medicago huberi E. Small Medicago rostrata (Boiss. (wikipedia.org)
- Medicago marina L. Medicago papillosa Boiss. (wikipedia.org)
- Medicago edgeworthii Sirjaev Medicago ovalis (Boiss. (wikipedia.org)
- Medicago plicata (Boiss. (wikipedia.org)
- Sirjaev Medicago ruthenica (L.) Ledebour Medicago blancheana Boiss. (wikipedia.org)
- Medicago noeana Boiss. (wikipedia.org)
- Medicago rotata Boiss. (wikipedia.org)
- Vaccines-focused biopharmaceutical company Medicago inked an agreement giving tobacco company Philip Morris International the license to develop the company's pandemic and seasonal influenza vaccines for China. (fiercepharma.com)
- Philip Morris will pay Medicago $4.5 million upfront and the biopharmaceutical company is eligible to receive development milestone payments totaling $7.5 million. (fiercepharma.com)
- A novel plant leucine-rich repeat receptor kinase regulates the response of Medicago truncatula roots to salt stress, Plant Cell , 2009, vol. 21, pp. 668-680. (springer.com)
- Metabolic profiling and systematic identification of flavonoids and isoflavonoids in roots and cell suspension cultures of Medicago truncatula using HPLC-UV-ESI-MS and GC-MS. (semanticscholar.org)
- In 2018, Medicago broke ground on the new $245 million manufacturing complex in Quebec City that will include the company's headquarters, research and development as well as production facilities. (biospace.com)
- The biotech firm Medicago USA Inc., based in Quebec City, Canada, recently broke ground on a planned 90,000-square-foot facility in Durham, North Carolina, that will make influenza vaccines using tobacco leaves. (vaccinenewsdaily.com)
- Medicago diverged from Glycine (soybean) about 53-55 million years ago (in the early Eocene), from Lotus (deervetch) 49-51 million years ago (also in the Eocene), and from Trigonella 10-22 million years ago (in the Miocene). (wikipedia.org)
- Extensive macrosynteny between Lotus and bean was uncovered on 8 of the 11 bean chromosomes and large blocks of macrosynteny were also found between bean and Medicago. (genetics.org)
- Lotus and Medicago are equally closely related to the bean and equally distantly related to Arachis ( D oyle and L uckow 2003 ). (genetics.org)
- The Arachis genetic map was substantially aligned with Lotus and Medicago with most synteny blocks presenting a single main affinity to each genome. (biomedcentral.com)
- We found that in Medicago and possibly also in Lotus , retrotransposons tend to be more frequent in the variable regions. (biomedcentral.com)
- The next step for Medicago is to demonstrate how its new-product development, based on the same platform, can expand into other areas beyond vaccines, such as those now reserved for antibodies and peptides. (pharmaceuticalonline.com)
- Medicago also will receive royalty payments on future sales of pandemic and seasonal influenza vaccines in China that use the company's technology. (fiercepharma.com)
- In addition to flu vaccines, in 2015, Medicago successfully completed a contract with the U.S. government (BARDA) to produce anti-Ebola antibodies. (biospace.com)