Meconium
Meconium Aspiration Syndrome
A condition caused by inhalation of MECONIUM into the LUNG of FETUS or NEWBORN, usually due to vigorous respiratory movements during difficult PARTURITION or respiratory system abnormalities. Meconium aspirate may block small airways leading to difficulties in PULMONARY GAS EXCHANGE and ASPIRATION PNEUMONIA.
Ileus
A condition caused by the lack of intestinal PERISTALSIS or INTESTINAL MOTILITY without any mechanical obstruction. This interference of the flow of INTESTINAL CONTENTS often leads to INTESTINAL OBSTRUCTION. Ileus may be classified into postoperative, inflammatory, metabolic, neurogenic, and drug-induced.
Intestinal Obstruction
Amniotic Fluid
A clear, yellowish liquid that envelopes the FETUS inside the sac of AMNION. In the first trimester, it is likely a transudate of maternal or fetal plasma. In the second trimester, amniotic fluid derives primarily from fetal lung and kidney. Cells or substances in this fluid can be removed for prenatal diagnostic tests (AMNIOCENTESIS).
Maternal-Fetal Exchange
Fetal Distress
Pregnancy
Substance Abuse Detection
Prenatal diagnosis of a lean umbilical cord: a simple marker for the fetus at risk of being small for gestational age at birth. (1/243)
OBJECTIVE: The purpose of this study was to investigate whether the prenatal diagnosis of a 'lean' umbilical cord in otherwise normal fetuses identifies fetuses at risk of being small for gestational age (SGA) at birth and of having distress in labor. The umbilical cord was defined as lean when its cross-sectional area on ultrasound examination was below the 10th centile for gestational age. METHOD: Pregnant women undergoing routine sonographic examination were included in the study. Inclusion criteria were gestational age greater than 20 weeks, intact membranes, and singleton gestation. The sonographic cross-sectional area of the umbilical cord was measured in a plane adjacent to the insertion into the fetal abdomen. Umbilical artery Doppler waveforms were recorded during fetal apnea and fetal anthropometric parameters were measured. RESULTS: During the study period, 860 patients met the inclusion criteria, of whom 3.6% delivered a SGA infant. The proportion of SGA infants was higher among fetuses who had a lean umbilical cord on ultrasound examination than among those with a normal umbilical cord (11.5% vs. 2.6%, p < 0.05). Fetuses with a lean cord had a risk 4.4-fold higher of being SGA at birth than those with a normal umbilical cord. After 25 weeks of gestation, this risk was 12.4 times higher when the umbilical cord was lean than when it was of normal size. The proportion of fetuses with meconium-stained amniotic fluid at delivery was higher among fetuses with a lean cord than among those with a normal umbilical cord (14.6% vs. 3.1%, p < 0.001). The proportion of infants who had a 5-min Apgar score < 7 was higher among those who had a lean cord than among those with normal umbilical cord (5.2% vs. 1.3%, p < 0.05). Considering only patients admitted in labor with intact membranes and who delivered an appropriate-for-gestational-age infant, the proportion of fetuses who had oligohydramnios at the time of delivery was higher among those who had a lean cord than among those with a normal umbilical cord (17.6% versus 1.3%, p < 0.01). CONCLUSION: We conclude that fetuses with a lean umbilical cord have an increased risk of being small for gestational age at birth and of having signs of distress at the time of delivery. (+info)Prophylactic cefazolin in amnioinfusions administered for meconium-stained amniotic fluid. (2/243)
OBJECTIVE: To determine if amnioinfusion with an antibiotic solution decreased the rate of clinical chorioamnionitis and puerperal endometritis in patients with meconium-stained amniotic fluid. METHODS: Patients in labor at 36 weeks of gestation or greater with singleton pregnancies and meconium-stained amniotic fluid were randomized to receive either cefazolin, 1 g/1,000 mL, of normal saline (n = 90) or normal saline (n = 93) amnioinfusion. Rates of clinically diagnosed chorioamnionitis and endometritis and of suspected and culture-proven neonatal infection were determined. RESULTS: Between the study and control groups, the incidences of clinical chorioamnionitis (7.8% vs. 8.6%), endometritis (2.4% vs. 3.5%), aggregate intrauterine infection (10.0% vs. 11.8%), suspected neonatal infection (17.8% vs. 21.5%), and proven neonatal infection (0.0% vs. 2.2%) were not significantly different. CONCLUSIONS: Prophylactic use of cefazolin in amnioinfusions did not significantly reduce rates of maternal or neonatal infection in patients with meconium-stained amniotic fluid. (+info)Bile acid patterns in meconium are influenced by cholestasis of pregnancy and not altered by ursodeoxycholic acid treatment. (3/243)
BACKGROUND: Data on meconium bile acid composition in newborn babies of patients with intrahepatic cholestasis of pregnancy (ICP) are relatively scant, and changes that occur on ursodeoxycholic acid (UDCA) administration have not been evaluated. AIMS: To investigate bile acid profiles in meconium of neonates from untreated and UDCA treated patients with ICP. Maternal serum bile acid composition was also analysed both at diagnosis and delivery to determine whether this influences the concentration and proportion of bile acids in the meconium. PATIENTS/METHODS: The population included eight healthy pregnant women and 16 patients with ICP, nine of which received UDCA (12.5-15.0 mg/kg body weight/day) for 15+/-4 days until parturition. Bile acids were assessed in the meconium by gas chromatography-mass spectrometry and in maternal serum by high performance liquid chromatography. RESULTS: Total bile acid and cholic acid concentrations in the meconium were increased (p<0.01) in newborns from patients with ICP (13.5 (5.1) and 8.4 (4.1) micromol/g respectively; mean (SEM)) as compared with controls (2.0 (0.5) and 0.8 (0.3) micromol/g respectively), reflecting the total bile acid and cholic acid levels in the maternal serum (r = 0.85 and r = 0.84, p<0.01). After UDCA administration, total bile acid concentrations decreased in the mother ( approximately 3-fold, p<0. 05) but not in the meconium. UDCA concentration in the meconium showed only a 2-fold increase after treatment, despite the much greater increase in the maternal serum (p<0.01). Lithocholic acid concentration in the meconium was not increased by UDCA treatment. CONCLUSIONS: UDCA administration does not influence the concentration and proportion of bile acids in the meconium, which in turn are altered by ICP. Moreover, this beneficial treatment for the mother does not increase meconium levels of potentially toxic metabolites of UDCA such as lithocholic acid. (+info)Immunoassay and GC-MS procedures for the analysis of drugs of abuse in meconium. (4/243)
The analysis of meconium specimens for metabolites of substances of abuse is a relatively accurate method for the detection of fetal exposure to drugs. Most of the methods reported in the literature before the early 1990s relied on radioimmunoassays. The purpose of this study was to develop and validate methods for meconium sample preparation for the screening and gas chromatography-mass spectrometry (GC-MS) confirmation of meconium extracts for cannabinoids, cocaine, opiates, amphetamines, and phencyclidine. EMIT and TDx immunoassays were evaluated as screening methods. The sample preparation method developed for screening included extraction and purification prior to analysis. Cutoff levels were administratively set at 20 ng/g for 11-nor-delta9-THC-9-COOH (THCCOOH) and phencyclidine and at 200 ng/g for benzoylecgonine, morphine, and amphetamines, although lower levels could be detected in meconium using the EMIT-ETS system. Ninety-five meconium specimens were subjected to the screening procedure with GC-MS confirmation of presumptive positives. In addition, 30 (40 for cocaine) meconium specimens were subjected to GC-MS analysis for all analytes regardless of the screening results to determine the false-negative rate, if any, of the immunoassay. Although there were no false negatives detected, the GC-MS confirmation rate for the immunoassay-positive specimens was generally low, ranging from 0% for amphetamines to 75% for opiates. The lowest rate of confirmed positives was found with the cannabinoids, suggesting that tetrahydrocannabinol (THC) metabolites other than free 11-nor-9-carboxy-delta9-THC may be major contributors to the immunoassay response in meconium. (+info)Identification and analysis of the major metabolites of cocaine in meconium. (5/243)
A gas chromatographic-mass spectrometric (GC-MS) method was used for the simultaneous analysis of cocaine and its metabolites (norcocaine, benzoylecgonine, norbenzoylecgonine, ecgonine methylester, cocaethylene, and the o-, m, and p-hydroxy derivatives of cocaine and benzoylecgonine) in meconium specimens collected from newborns prenatally exposed to the drug in an effort to determine which of these metabolites are more relevant in the confirmation of immunoassay-positive specimens. Significant metabolites included benzoylecgonine and its m- and p-hydroxy derivatives. Reanalysis of immunoassay-positive meconium specimens that previously failed to confirm by GC-MS for benzoylecgonine revealed that the GC-MS confirmation rate could be substantially enhanced by inclusion of m- and p-hydroxybenzoylecgonine in the analysis along with benzoylecgonine. Several specimens were found to be positive for hydroxylated derivative(s) in the absence of benzoylecgonine itself. (+info)Level of in utero cocaine exposure and neonatal ultrasound findings. (6/243)
OBJECTIVE: To assess whether there is an association between the level of in utero cocaine exposure and findings on neonatal cranial ultrasound, controlling for potentially confounding variables. STUDY DESIGN: In a prospective longitudinal study, three cocaine exposure groups were defined by maternal report and infant meconium assay: unexposed, heavier cocaine exposure (>75th percentile self-reported days of use or of meconium benzoylecogonine concentration) or lighter cocaine exposure (all others). Neonatal ultrasounds from 241 well, term infants were read by a single radiologist who was masked to the exposure group. RESULTS: Infants with lighter cocaine exposure did not differ from the unexposed infants on any ultrasound findings. After controlling for infant gender, gestational age, and birth weight z scores and for maternal parity, blood pressure in labor, ethnicity, and use of cigarettes, alcohol, and marijuana during pregnancy, the more heavily cocaine-exposed infants were more likely than the unexposed infants to show subependymal hemorrhage in the caudothalamic groove (covariate adjusted odds ratio: 3.88; 95% confidence interval: 1.45, 10.35). CONCLUSIONS: This is the first study to demonstrate that ultrasound findings suggestive of vascular injury to the neonatal central nervous system are related to the level of prenatal cocaine exposure. Inconsistency in previous research in identifying an association between prenatal cocaine exposure and neonatal cranial ultrasound findings may reflect failure to consider dose effects. (+info)Failure to pass meconium: diagnosing neonatal intestinal obstruction. (7/243)
Timely passage of the first stool is a hallmark of the well-being of the newborn infant. Failure of a full-term newborn to pass meconium in the first 24 hours may signal intestinal obstruction. Lower intestinal obstruction may be associated with disorders such as Hirschsprung's disease, anorectal malformations, meconium plug syndrome, small left colon syndrome, hypoganglionosis, neuronal intestinal dysplasia and megacystis-microcolon-intestinal hypoperistalsis syndrome. Radiologic studies are usually required to make the diagnosis. In addition, specific tests such as pelvic magnetic resonance imaging, anorectal manometry and rectal biopsy are helpful in the evaluation of newborns with failure to pass meconium. (+info)m-hydroxy benzoylecgonine recovery in fetal guinea pigs. (8/243)
Recently, meta-hydroxybenzoylecgonine (m-OH BE) was identified by gas chromatography-mass spectroscopy during quantitative analysis for cocaine. Identification of m-OH BE in addition to the routinely identified benzoylecgonine by gas chromatography-mass spectroscopy confirmatory assays may increase detection of cocaine-exposed infants and decrease false negative results. However, it is not known whether m-OH BE is derived directly from benzoylecgonine or from hydroxylated cocaine, or whether this metabolite is produced in the fetus or transferred across the placenta from the maternal circulation. We quantitated the recovery of cocaine, benzoylecgonine, and m-OH BE from amniotic fluid, fetal meconium, fetal intestine, and maternal urine for up to 4 days after single dose administration of either cocaine or benzoylecgonine to pregnant time-bred guinea pigs. m-OH BE was recovered from meconium after maternal injections of cocaine and benzoylecgonine. There was no significant detection of m-OH BE from amniotic fluid or intestine and minimal recovery from maternal urine after either cocaine or benzoylecgonine administration. Detection of m-OH BE in meconium increased the identification of in utero exposed guinea pigs, and the greatest yield of m-OH BE from meconium occurred later than that observed for cocaine or benzoylecgonine. (+info)
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Meconium
... ileus should be distinguished from meconium plug syndrome, in which a tenacious mass of mucus prevents the meconium ... The meconium sometimes becomes thickened and congested in the intestines, a condition known as meconium ileus. Meconium ileus ... meconium plug syndrome shows a normal or dilated colon as compared to micro-colon in meconium ileus. Meconium can be tested for ... Terminal meconium occurs when the fetus passes the meconium a short enough time before birth/cesarean section that the amniotic ...
Meconium peritonitis
... refers to rupture of the bowel prior to birth, resulting in fetal stool (meconium) escaping into the ... Infants with cystic fibrosis are at increased risk for meconium peritonitis. Twenty percent of infants born with meconium ... Adhesiolysis partial resection of pseudocyst covering enterostomy.[citation needed] Meconium peritonitis was first described in ... "The natural history of meconium peritonitis diagnosed in utero". Journal of Pediatric Surgery. 30 (7): 979-82. doi:10.1016/0022 ...
Meconium aspiration syndrome
... (MAS) also known as neonatal aspiration of meconium is a medical condition affecting newborn ... Additionally, foetal distress occurs frequently without the passage of meconium as well. Although meconium is present in the ... Medicine portal Aspiration pneumonia Van Ierland, Y; De Beaufort, AJ (2009). "Why Does Meconium Cause Meconium Aspiration ... Vain, NE; Batton, DG (2017). "Meconium "Aspiration" (or Respiratory Distress Associated with Meconium-Stained Amniotic Fluid ...
Birth injury
Meconium is a sticky substance that usually makes up the child's first bowel movement. If the fetus is stressed before or ... If it gets into the child's airways or lungs, it can cause meconium aspiration syndrome. Serious cases may result in pneumonia ... "Meconium aspiration". March of Dimes. 21 September 2010. Retrieved 13 December 2017. "Pregnancy Complications". Center for ... "Meconium aspiration". 21 September 2010. Larson, Aaron (8 November 2014). "Common Birth Injuries and Medical Malpractice". ...
Fetal distress
Meconium in the amniotic fluid If a fetus has meconium in their lungs when they are born, this prevents the pressure in their ... Decreased movement felt by the mother Meconium in the amniotic fluid ("meconium stained fluid") Non-reassuring patterns seen on ... Since aspiration of meconium can lead to improper oxygenation due to obstruction and carries the potential risk for ... It is characterized by changes in fetal movement, growth, heart rate, and presence of meconium stained fluid. Risk factors for ...
Opium
The word meconium (derived from the Greek for "opium-like", but now used to refer to newborn stools) historically referred to ... "HON Mother & Child Glossary, Meconium". hon.ch. Archived from the original on May 1, 2021. Retrieved April 4, 2016. Sawynok J ( ...
Adaptation to extrauterine life
Passing of meconium also occurs. Physiology: In utero, the placenta delivers oxygenated blood to the fetus through the ...
Pneumonia
Suctioning the mouth and throat of infants with meconium-stained amniotic fluid has not been found to reduce the rate of ... Roggensack A, Jefferies AL, Farine D (April 2009). "Management of meconium at birth". Journal of Obstetrics and Gynaecology ...
Amnioinfusion
It has also been used to reduce the risk of meconium aspiration syndrome, though evidence of benefit is mixed. The UK National ... Amnioinfusion for meconium-stained liquor in labour. Cochrane Database Syst Rev 2014; 1:CD000014. Stenson, Benjamin James; ... September 2005). "Amnioinfusion for the prevention of the meconium aspiration syndrome". N. Engl. J. Med. 353 (9): 909-17. doi: ... Edwards RK, Duff P (1999). "Prophylactic cefazolin in amnioinfusions administered for meconium-stained amniotic fluid". Infect ...
Karta (orangutan)
The unborn baby had aspirated meconium. Subsequently the zoo received more than 2,500 expressions of condolence. Funds were ...
1905 in science
Karl Landsteiner first describes Meconium ileus. Fritz Schaudinn and Erich Hoffmann discovered the bacterium that was ...
Fetal circulation
The presence of meconium within the lungs, known as meconium aspiration syndrome, can obstruct the airways and also deactivate ... In both cases of infant respiratory distress syndrome and meconium aspiration syndrome, fetal shunts will remain open due to ... In addition, occasionally during birth, infants may inhale remnants of their fecal matter known as meconium, preventing ... The inflammation that also results from the inhalation of meconium also causes airway constriction, resulting in poor ...
Respiratory disease
Meconium Aspiration Syndrome occurs in full term or post-term infants who aspirate meconium. Risk factors include a diabetic ... Its diagnosis is based on meconium stained amniotic fluid at delivery and staining on the skin, nails, and umbilical cord. ... "Meconium aspiration syndrome: MedlinePlus Medical Encyclopedia". medlineplus.gov. Retrieved 2022-05-11. Steinhorn, Robin H. ( ... There are three main causes of PPHN are parenchymal diseases such as meconium aspiration syndrome, idiopathic, and hypoplastic ...
Timeline of human prenatal development
Meconium is made in the intestinal tract. The liver and pancreas produce fluid secretions. From week 13, sex prediction by ...
Initial acquisition of microbiota
The meconium of term offspring delivered by these mice via sterile C-section was found to contain labeled E. faecium, while ... The meconium, an infant's first bowel movement of digested amniotic fluid, has also been shown to contain a diverse community ... April 2008). "Is meconium from healthy newborns actually sterile?". Research in Microbiology. 159 (3): 187-193. doi:10.1016/j. ...
Gut microbiota
"Is meconium from healthy newborns actually sterile?". Research in Microbiology. 159 (3): 187-93. doi:10.1016/j.resmic.2007.12. ... as well as in the meconium of babies born by sterile cesarean section. In another study, researchers administered a culture of ...
Human feces
Meconium is a newborn baby's first feces. Human fecal matter varies significantly in appearance, depending on diet and health. ...
Uterine microbiome
He wrote that meconium from the newborn was free of bacteria. There was a general consensus at the time and even recently that ... Other investigations used sterile diapers for meconium collection. No bacteria were able to be cultured from the samples. Other ... studies showed that bacteria were detected and were directly proportional to the time between birth and the passage of meconium ...
Neonatal bowel obstruction
The differential for low obstruction is ileal atresia, meconium ileus, meconium plug syndrome and Hirschsprung disease. In ... Radiographs in meconium ileus classically demonstrate a bubbly appearance in the right lower quadrant due to a combination of ... The neonatal bowel obstruction is suspected based on polyhydramnios in utero, bilious vomiting, failure to pass meconium in the ... Loening-Baucke, Vera; Kimura, Ken (Nov 1, 1999). "Failure to Pass Meconium: Diagnosing Neonatal Intestinal Obstruction". ...
Vaginal flora in pregnancy
He wrote that meconium from the newborn was free of bacteria. This was interpreted as the uterine environment was sterile. ... Bacteria were detected and were directly proportional to the time between birth and the passage of meconium. Africa, Charlene; ... Other investigations used sterile diapers for meconium collection. No bacteria were able to be cultured from the samples. ...
Amnion
Meconium-laden macrophages in meconium stained fetal membranes. H&E stain. Opened uterus with cat fetus in midgestation: 1 ...
Placental microbiome
He wrote that meconium from the newborn was free of bacteria. This was interpreted as the uterine environment was sterile. ... Bacteria were detected and were directly proportional to the time between birth and the passage of meconium. A 1927 study ... Other investigations used sterile diapers for meconium collection. No bacteria were able to be cultured from the samples. ...
Hirschsprung's disease
... meconium) within 48 hours of delivery. Normally, 90% of babies pass their first meconium within 24 hours, and 99% within 48 ... Kimura, Ken; Loening-Baucke, Vera (1999-11-01). "Failure to Pass Meconium: Diagnosing Neonatal Intestinal Obstruction". ...
Surfactant therapy
Respiratory care Nursing Neonatology Meconium aspiration syndrome Tarawneh, A; Kaczmarek, J; Bottino, M N; Sant'Anna, G M (7 ...
Persistent fetal circulation
Causes include hypoxia, meconium aspiration, and respiratory distress syndrome. Left untreated, this can lead to hypoxic ... To help with diagnosis, the clinician can watch out for predisposing factors, such as: birth asphyxia, meconium aspiration, use ...
Nuchal cord
Complications can include meconium, respiratory disease, anemia, and still birth. Petechiae and subconjunctival bleeding due to ... Complications can include meconium, respiratory distress, anemia, and stillbirth. Multiple wraps are associated with greater ...
Joseph Harold Sheldon
with Hugh Ramage: Ramage, H.; Sheldon, J. H. (1933). "A spectrographic analysis of the metallic content of meconium". Biochem J ...
Lucinactant
... is also used to treat meconium aspiration syndrome. Lucinactant contains the peptide sinapultide (KL4 acetate, ... lavage with standard care for treatment of meconium aspiration syndrome". Pediatrics. 109 (6): 1081-7. doi:10.1542/peds.109.6. ... 07-30-1996 Treatment of meconium aspiration syndrome in newborn infants 07-17-1995 Treatment of acute respiratory distress ...
Vitelline duct
This results in discharge of meconium from the umbilicus. About two percent of fetuses exhibit a type of vitelline fistula ...
Intestinal atresia
Ileal atresia can also result as a complication of meconium ileus.[citation needed] A third of infants with intestinal atresia ... This can lead to abdominal tenderness and meconium peritonitis, which can be fatal. Intestinal atresia occurs in around 1 in ... Other features include abdominal distension and failure to pass meconium. The distension is more generalised the further down ... Rather, abdominal tenderness is a symptom of the late complication meconium peritonitis. Before birth, excess amniotic fluid ( ...
Meconium: MedlinePlus Medical Encyclopedia Image
Meconium is composed of amniotic fluid, mucus, lanugo (the fine hair that covers the babys body), bile, and cells that have ... The first bowel movement a baby has is called meconium. ... Meconium is composed of amniotic fluid, mucus, lanugo (the fine ... The first bowel movement a baby has is called meconium. ...
Midwifery Today On Meconium at Home and Delayed Cord-cutting The heart and science of birth
This homebirth midwife shares her experience in successfully handling babies who pass meconium prior to birth. ... On Meconium at Home and Delayed Cord-cutting. by Naolí Vinaver , December 1, 2006 ... This homebirth midwife shares her experience in successfully handling babies who pass meconium prior to birth. This post is ...
Meconium Aspiration Syndrome
... , Meconium Aspiration, Meconium Aspiration Pneumonia, Meconium Pneumonitis. ... Meconium Aspiration Syndrome. search Meconium Aspiration Syndrome, Meconium Aspiration, Meconium Aspiration Pneumonia, Meconium ... Meconium Aspiration results in severe airway inflammation and Pneumonia risk. *Meconium Aspiration occurs in utero, not at ... Amnioinfusion does not decrease Meconium Aspiration risk. *Fraser (2005) N Engl J Med 353:909-17 [PubMed] ...
Is my child suffering from meconium aspiration syndrome?
b,But the baby passed stool in the womb.,/b, As far as I can understand this condition is called meconium aspiration syndrome ( ... Is my child suffering from meconium aspiration syndrome?. Answered by: Dr Anurag Krishna , Director of Paediatrics and ... But the baby passed stool in the womb. As far as I can understand this condition is called meconium aspiration syndrome (MAS). ... A:Only if the baby has breathing difficulty, it is called Meconium aspiration syndrome, when it may cause problems. If the baby ...
PRIME PubMed | Measurement of cocaine and metabolites in urine, meconium, and diapers by gas chromatography/mass spectrometry
... meconium, and diapers by gas chromatography/mass spectrometry. Download Prime PubMed App to iPhone, iPad, or Android ... CocaineGas Chromatography-Mass SpectrometryHumansIndicator Dilution TechniquesInfant CareInfant, NewbornMeconiumSensitivity and ... Methanolic extracts from meconium and diapers were reconstituted in drug-free urine and treated as above. The limit of ... Methanolic extracts from meconium and diapers were reconstituted in drug-free urine and treated as above. The limit of ...
Meconium analysis to detect fetal exposure to neurotoxicants | Archives of Disease in Childhood
Meconium and neurotoxicants: searching for a prenatal exposure timing. J A Ortega García D Carrizo Gallardo J Ferris i ... Meconium is formed by the fetus as early as the 12th week of gestation, accumulates throughout pregnancy, and is normally ... Meconium is therefore a repository of many of the xenobiotics that the fetus is exposed to throughout pregnancy and its ... In addition, meconium has also been successfully analysed to detect fetal exposure to various licit drugs and over the counter ...
Using meconium to establish prenatal alcohol exposure in the UK: ethical, legal and social considerations | Journal of Medical...
Using meconium to establish prenatal alcohol exposure in the UK: ethical, legal and social considerations ... Using meconium to establish prenatal alcohol exposure in the UK: ethical, legal and social considerations ... We ask the overarching question, Can routine screening of meconium to establish PAE be ethically or legally justified, and we ... First, we consider the reasons why meconium screening should not be deemed typical within the scope of accepted screening ...
WHO EMRO | Toxic metals in maternal blood, cord blood and meconium of newborn infants in Pakistan | Volume 23, issue 10 | EMHJ...
All our meconium samples tested positive for toxic metals and trace elements. Meconium reflects fetal exposure to toxic metals ... The results of 1034 samples of cord blood, maternal blood and meconium are shown in Tables 2-7. The meconium contained higher ... Actual quantitative weight of meconium was also done at the laboratory. The average baby passes the meconium in first 24 to 48 ... A total of 1034 samples were collected (meconium, maternal blood and cord blood). Of these, 606 were paired samples (meconium n ...
Meconium Aspiration Syndrome<...
Meconium Aspiration Syndrome is considered a serious medical issue that can lead to birth injuries like cerebral palsy. ... Meconium Aspiration Syndrome Hydrocephalus Pitocin Errors Anesthesia Errors Infertility Drugs Cerebral Dysgenesis and Cerebral ... About Meconium Aspiration Syndrome. According to a clinical study published by the U.S. National Institutes of Health, meconium ... Meconium aspiration syndrome birth injury (MAS), sometimes referred to as neonatal aspiration of meconium, is a medical ...
JaypeeDigital | Meconium Aspiration Syndrome, Persistent Pulmonary Hypertension, and Air Leak
Phencyclidine (PCP) Confirmation, Chain of Custody, Meconium - Mayo Clinic Laboratories Rochester
Meconium Specimen Required. Supplies: Chain of Custody Meconium Kit (T653) includes the specimen containers, seals, and ... Test ID PCPMX Phencyclidine (PCP) Confirmation, Chain of Custody, Meconium Useful For. Detection of in utero drug exposure up ... 1. Chain of Custody Request is included in the Chain-of-Custody Meconium Kit (T653). ...
Early management of meconium ileus in infants with cystic fibrosis: A prospective population cohort study. - Nuffield...
Live-born infants with bowel-obstruction from inspissated meconium in the terminal ileum and CF were reported. Data are ... Contemporary early outcome data of meconium Ileus (MI) in cystic fibrosis (CF) are lacking on a population level. We describe ... Early management of meconium ileus in infants with cystic fibrosis: A prospective population cohort study. ... Early management of meconium ileus in infants with cystic fibrosis: A prospective population cohort study. ...
Meconium Plug Syndrome - Children's Health Issues - MSD Manual Consumer Version
Meconium Plug Syndrome - Learn about the causes, symptoms, diagnosis & treatment from the MSD Manuals - Medical Consumer ... Meconium ileus Meconium Ileus Meconium ileus is blockage of the small intestine in a newborn caused by excessively thick ... Meconium, a dark green material, is a newborns first stool. Newborns expel meconium at or shortly after birth. If the meconium ... Meconium ileus usually results... read more is similar to meconium plug syndrome except that it is the small intestine that is ...
Spectrophotometric Determination of Meconium Concentration in Amniotic Fluid<...
Spectrophotometric Determination of Meconium Concentration in Amniotic Fluid. / Francoul, J.; Molcho, J.; Lieberman, J. R. ... Spectrophotometric Determination of Meconium Concentration in Amniotic Fluid. Journal of Biomedical Engineering. 1987 Jul;9(3): ... Francoul, J. ; Molcho, J. ; Lieberman, J. R. / Spectrophotometric Determination of Meconium Concentration in Amniotic Fluid. In ... Francoul, J, Molcho, J & Lieberman, JR 1987, Spectrophotometric Determination of Meconium Concentration in Amniotic Fluid, ...
CLINICAL USE OF MECONIUM FATTY ACID ETHYL ESTERS FOR IDENTIFYING CHILDREN AT RISK FOR ALCOHOL- RELATED DISABILITIES: THE FIRST...
The neonates meconium tested high for FAEEs (52 nmol/g; positive cut-off ?2 nmol/g), which prompted active follow-up of the ... in meconium are validated biomarkers of heavy fetal alcohol exposure that may potentially be used clinically for identifying ... The neonates meconium tested high for FAEEs (52 nmol/g; positive cut-off ?2 nmol/g), which prompted active follow-up of the ... Ethyl linoleate in meconium: a biomarker for prenatal ethanol exposure. Alcohol Clin Exp Res 1999;23:487-493. 20. Mattson SN, ...
Cardiopulmonary Resuscitation (CPR): Practice Essentials, Background, Indications & Contraindications
Meconium-stained amniotic fluid. The 2015 AHA guidelines offer the following revised recommendations for infants born with ... What are the AHA recommendations for cardiopulmonary resuscitation (CPR) in neonates with meconium-stained amniotic fluid? ... meconium-stained amniotic fluid [49] :. * Initial steps of resuscitation should be completed under the radiant warmer and PPV ...
IMSEAR at SEARO: Giant cystic meconium peritonitis.
Meconium Aspirator | Medpick
Meconium Stained Amniotic Fluid
Meconium aspiration syndrome (MAS) - happened in up to 5% of babies with meconium-stained amniotic fluid, and up to 30% of them ... The initial reason that the meconium appeared - again, meconium staining may indicate certain neonatal distress. The reason for ... meconium). This is what gives the amniotic fluid the greenish brown meconial staining.. This means, that meconium staining is ... What is meconium-stained amniotic fluid?. The baby grows in the clear amniotic fluid environment in the uterus.. When theres ...
Meconium | Biocodex Microbiota Institute
Meconium Ileus | Profiles RNS
"Meconium Ileus" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... This graph shows the total number of publications written about "Meconium Ileus" by people in this website by year, and whether ... Intestinal obstruction caused by congealed MECONIUM in the distal ILEUM and CECUM. It presents shortly after birth as a failure ... Below are the most recent publications written about "Meconium Ileus" by people in Profiles. ...
Update to Meconium Collection - USDTL
Prevent the meconium specimen from coming in contact with ANY ethanol-based liquids or vapors at ANY TIME previous to, and ... We will not test the meconium for FAEE if the specimen was collected more than 18 hours after birth. If the final time of ... Because of such progress, we have some important updates to the meconium collection process. Effective October 1st, 2016, the ...
Intubation and Tracheal Suctioning for Meconium Aspiration: Overview, Periprocedural Care, Technique
The term meconium is derived from the Greek word mekonion, which means poppy juice or opium, presumably either because of its ... Background Meconium is a viscous green-black substance that consists of denuded intestinal epithelial cells, ingested lanugo ... Pathophysiology of meconium aspiration. Image adapted from Wiswell T, Bent RC. Meconium staining and the meconium aspiration ... Pathophysiology of meconium aspiration. Image adapted from Wiswell T, Bent RC. Meconium staining and the meconium aspiration ...
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Cystic Fibrosis Clinical Presentation: History, Physical Examination
Meconium ileus occurs in 7-10% of patients with cystic fibrosis. Patients with simple meconium ileus usually present with ... meconium peritonitis). Less commonly, passage of meconium may be delayed (,24-48 hours after birth) or cholestatic jaundice may ... Meconium ileus. Often, examination reveals dilated loops of bowel with a doughy character that indent on palpation. The rectum ... Meconium ileus and its complications. A reappraisal of plain film roentgen diagnostic criteria. Am J Roentgenol Radium Ther ...
Water Birth: Pros, Cons, and What You Need to Know
Meconium aspiration This medical term means a baby has had its first bowel movement before birth and inhales the contaminated ... Doctors and midwives are able to tell if this has happened when the water breaks because meconium is typically green, sticky, ... Pneumonia usually develops within the first 24 to 48 hours after birth, and it is caused by meconium aspiration, fecal ... These range from infection to meconium aspiration to drowning. To clear common misconceptions, heres everything parents-to-be ...
Meconium plug in newborn | Gamuts.net
Colic & low Lactobacillus count in the meconium
Result: The meconium microbiome in infants diagnosed with infantile colic (n = 19) was different to that in infants not ... 4.6%, p = 0.04) in their meconium. This difference could no longer be detected in the follow-up samples taken one year later. ... Studies have shown that the meconium already contains a diverse microbiome and that colonisation of the infant intestine begins ... Study design: The prospective, population-based cohort study collected the meconium of 212 consecutive newborns, analysed its ...
Infant and Maternal Characteristics in Neonatal Abstinence Syndrome - Selected Hospitals in Florida, 2010-2011
Jennifer N. Lind, PharmD1,2,3, Emily E. Petersen, MD1,3,4, Philip A. Lederer, MD1,3,5, Ghasi S. Phillips-Bell, ScD4,6, Cria G. Perrine, PhD2,3, Ruowei Li, MD2, Mark Hudak, MD7, Jane A. Correia6, Andreea A. Creanga, MD4, William M. Sappenfield, MD8, John Curran, MD9, Carina Blackmore, PhD6, Sharon M. Watkins, PhD6, Suzanne Anjohrin, MPH6 (Author affiliations at end of text). Neonatal abstinence syndrome (NAS) is a constellation of physiologic and neurobehavioral signs exhibited by newborns exposed to addictive prescription or illicit drugs taken by a mother during pregnancy (1). The number of hospital discharges of newborns diagnosed with NAS has increased more than 10-fold (from 0.4 to 4.4 discharges per 1,000 live births) in Florida since 1995, far exceeding the three-fold increase observed nationally (1,2). In February 2014, the Florida Department of Health requested the assistance of CDC to 1) assess the accuracy and validity of using Floridas hospital inpatient discharge data, linked to ...
Amniotic fluidPassage of meconiumInfantsPass meconiumIleusStoolNeonatesCystic fibrosisNeonatalCondition is called meconium aspiratiIntestinalNewbornsBaby'sSimilar to meconiumInhale the meconiumUteroBowelPneumoniaGestational agePrenatal exposureTerm meconiumMaternalWeeks of gestatCongenitalEndotrachealMethodsGreenish blackFetusRespiratory DistressSpecimenOutcomesAspiratorPeritonitisFetal hypoxiaThickHypoxiaPathophysiologyStoolsOutcomeSymptomsWombPersistentBabiesMetabolitesAmnioinfusionUrineVaginalExposureBirthLungs
Amniotic fluid33
- Meconium is composed of amniotic fluid, mucus, lanugo (the fine hair that covers the baby's body), bile, and cells that have been shed from the skin and the intestinal tract. (medlineplus.gov)
- Throughout gestation, xenobiotics and their metabolites are principally deposited in meconium either directly from bile secretion or from fetal swallowing of amniotic fluid which contains these compounds which are excreted via the fetal urine. (bmj.com)
- According to a clinical study published by the U.S. National Institutes of Health, meconium "contains residues of bile, intestinal juice, swallowed amniotic fluid containing lanugo hair, and chemical substances like lipids, carbohydrates, nitrogen, and electrolytes. (cerebralpalsyguidance.com)
- The meconium then mixes in with the amniotic fluid surrounding the infant. (cerebralpalsyguidance.com)
- Johns Hopkins reports that, while around 6-25% of all newborns have "meconium-stained amniotic fluid," only about 11% will develop MAS . (cerebralpalsyguidance.com)
- 2 . Meconium aspiration syndrome (MAS) - happened in up to 5% of babies with meconium-stained amniotic fluid, and up to 30% of them, require mechanical ventilation because of this complication. (dr-efi.com)
- What will happen in the future of a baby with meconium-stained amniotic fluid? (dr-efi.com)
- Meconium aspiration syndrome (MAS) occurs when meconium-stained amniotic fluid (MSAF) is aspirated into the lungs of an infant before, during, or immediately after birth (see the image below). (medscape.com)
- Infants with meconium-stained amniotic fluid, regardless of whether they are vigorous or not, should no longer routinely receive intrapartum suctioning. (medscape.com)
- Resuscitation should follow the same principles for infants with meconium-stained fluid as for those with clear amniotic fluid. (medscape.com)
- Unlike later feces, meconium is composed of materials ingested during the time the infant spends in the uterus: intestinal epithelial cells, lanugo, mucus, amniotic fluid, bile and water. (gamuts.net)
- Desai D, Maitra N, Patel P. Fetal heart rate patterns in patients with thick meconium staining of amniotic fluid and its association with perinatal outcome. (ijrcog.org)
- Perinatal outcome of meconium stained amniotic fluid among labouring mothers at teaching referral hospital in urban Ethiopia. (ijrcog.org)
- Samiyappa DP, Ghose S, John LB, Samal R. Maternal and perinatal outcome in meconium stained amniotic fluid at term: a study population control study. (ijrcog.org)
- Intrapartum and perinatal results associated with different degrees of staining of meconium stained amniotic fluid. (ijrcog.org)
- To estimate the rates of meconium-stained amniotic fluid (AF) and adverse outcome in relation to gestational age and racial group, and to investigate the predictors of meconium-stained AF. (qxmd.com)
- Racial disparity in meconium-stained amniotic fluid and meconium aspiration syndrome in the United States, 1989-2000. (qxmd.com)
- The epidemiology of meconium stained amniotic fluid on hospital basis]. (qxmd.com)
- Determinants of meconium-stained amniotic fluid in term pregnancies. (qxmd.com)
- Meconium stained amniotic fluid in preterm delivery is an independent risk factor for perinatal complications. (qxmd.com)
- Meconium passed in labor: how reassuring is clear amniotic fluid? (qxmd.com)
- Maternal and perinatal outcome of patients with preterm labor and meconium-stained amniotic fluid. (qxmd.com)
- Meconium-stained amniotic fluid across gestation and neonatal acid-base status. (qxmd.com)
- Risk of meconium-stained amniotic fluid in different ethnic groups. (qxmd.com)
- Outcomes of endotracheal suctioning in non-vigorous neonates born through meconium-stained amniotic fluid: a systematic review and meta-analysis. (bvsalud.org)
- We conducted a systematic review of non-ETS and ETS in non-vigorous infants born through meconium -stained amniotic fluid (MSAF). (bvsalud.org)
- View of What is the amniotomy effect on non stress test in patients meconium stained amniotic fluid? (medscidiscovery.com)
- Meconium can lead to pulmonary injury by various mechanisms, which in the presence of respiratory distress and other radiological findings in neonates born with meconium-stained amniotic fluid (MSAF), are defined as meconium aspiration syndrome (MAS). (ac.ir)
- When babies are developing in the uterus, they ingest and then excrete amniotic fluid every day and meconium is a build-up of material, including amniotic fluid that happens during pregnancy. (gynob.com)
- Meconium, when passed in utero, can mix with the amniotic fluid and can get into the baby's lungs. (gynob.com)
- If there is meconium in the amniotic fluid, then the waters will be greenish or yellowish. (gynob.com)
- 5 EBOV RNA has also been detected in amniotic fluid, placental tissue, fetal meconium, vaginal secretions, umbilical cord, and buccal swab samples from neonates. (cdc.gov)
- Abstract Objective: to compare the use of non-invasive midwifery care technologies (TNICEO) with the use of traditional care model practices, having as parameters the presence of meconium in the amniotic fluid and its repercussion on the newborn's vitality. (bvsalud.org)
Passage of meconium2
- The passage of meconium prior to delivery, which occurs in 5%-25% of term births, causes nearly 5% of neonates to develop meconium aspiration syndrome (MAS) [ 10 ]. (e-cep.org)
- Meconium staining liquor (MSL) results from passage of meconium during labour and is used to diagnose fetal distress. (ijrcog.org)
Infants14
- The aim of this study was to quantify toxic metals lead, cadmium and trace elements zinc, copper, aluminium (Al) and Iron (Fe) levels in pregnant women, cord blood and meconium of new-born infants from industrial zones of Karachi, Pakistan. (who.int)
- Early management of meconium ileus in infants with cystic fibrosis: A prospective population cohort study. (ox.ac.uk)
- Live-born infants with bowel-obstruction from inspissated meconium in the terminal ileum and CF were reported. (ox.ac.uk)
- Population baseline of meconium fatty acid ethyl esters among infants of nondrinking women in Jerusalem and Toronto. (jptcp.com)
- It presents shortly after birth as a failure to pass meconium and frequently occurs in infants with CYSTIC FIBROSIS. (ouhsc.edu)
- [ 2 ] In term and postterm infants without fetal distress, intrauterine meconium passage may result from normal gastrointestinal (GI) maturation or from vagal stimulation caused by head or cord compression. (medscape.com)
- The meconium microbiome in infants diagnosed with infantile colic (n = 19) was different to that in infants not suffering from any symptoms (n = 139): colicky infants had a lower relative abundance of phylum Firmicutes (27% vs. 46%, p = 0.008) and Lactobacillus (0.54% vs. 4.6%, p = 0.04) in their meconium. (hipp.com)
- The steroids in meconium from normal male and female newborn infants have been studied by gas chromatography‐mass spectrometry. (houstonmethodist.org)
- Gustafsson, JÅ & Stenberg, Å 1971, ' Steroids in Meconium from Male and Female Newborn Infants ', European Journal of Biochemistry , vol. 22, no. 2, pp. 246-256. (houstonmethodist.org)
- Four studies, including 581 non-vigorous meconium -stained infants , fulfilled the inclusion criteria, comprising 292 infants in the non-ETS group and 289 in the ETS group. (bvsalud.org)
- Initiating ETS soon after birth in non-vigorous meconium -stained infants may not alter their neonatal outcomes. (bvsalud.org)
- Methods: Meconium, transitional, and mature stool samples collected from preterm neonates and older infants (ranging from a few days to weeks in age) were analyzed by a bench-top spectrometer to measure light absorbance in the near infrared range (650-950 nm). (elsevier.com)
- An example of the value of ECMO is the improved survival rate as high at 95% for infants with meconium aspiration syndrome , a somewhat rare but potentially serious condition. (childrensnational.org)
- Results were robust to extreme value imputation and exclusion of infants with meconium ileus. (cdc.gov)
Pass meconium6
- This homebirth midwife shares her experience in successfully handling babies who pass meconium prior to birth. (midwiferytoday.com)
- After birth, newborns usually pass meconium in the first 12 to 24 hours. (msdmanuals.com)
- However, newborns with meconium plug syndrome do not pass meconium within the first day or two and also have symptoms of intestinal blockage, including vomiting and abdominal swelling. (msdmanuals.com)
- Doctors suspect meconium plug syndrome in newborns who have symptoms of blockage and do not pass meconium within the first day or two. (msdmanuals.com)
- Patients with simple meconium ileus usually present with abdominal distension at birth, eventually progressing to failure to pass meconium, bilious vomiting, and progressive abdominal distension. (medscape.com)
- In the first days of life outside the womb, he will pass meconium, which is typically greenish-black in color. (gynob.com)
Ileus9
- BACKGROUND: Contemporary early outcome data of meconium Ileus (MI) in cystic fibrosis (CF) are lacking on a population level. (ox.ac.uk)
- Meconium Ileus" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ouhsc.edu)
- This graph shows the total number of publications written about "Meconium Ileus" by people in this website by year, and whether "Meconium Ileus" was a major or minor topic of these publications. (ouhsc.edu)
- Below are the most recent publications written about "Meconium Ileus" by people in Profiles. (ouhsc.edu)
- Neonates may present with meconium ileus or, rarely, with other features such as anasarca. (medscape.com)
- Meconium ileus occurs in 7-10% of patients with cystic fibrosis. (medscape.com)
- Patients with complicated meconium ileus present more dramatically at birth with severe abdominal distention, sometimes accompanied by abdominal wall erythema and edema. (medscape.com)
- We sought to determine whether the minimally invasive transamniotic route could be an alternative for fetal mRNA administration, as well as for delivery of cystic fibrosis (CF) transmembrane conductance regulator (CFTR) mRNA to the fetal intestine, the latter as a potential strategy for the prevention of CF-associated meconium ileus. (mcacs.org)
- Transamniotic fetal mRNA delivery could become a practicable novel strategy for the perinatal management of a variety of diseases, including the prevention of meconium ileus associated with cystic fibrosis. (mcacs.org)
Stool9
- Meconium aspiration syndrome birth injury (MAS), sometimes referred to as neonatal aspiration of meconium, is a medical condition that affects newborns born with stool, called meconium, that has gotten into their lungs. (cerebralpalsyguidance.com)
- Meconium, a dark green material, is a newborn's first stool. (msdmanuals.com)
- Meconium constitutes the first stool of a newborn infant. (medscape.com)
- Meconium is the earliest stool of a mammalian infant. (gamuts.net)
- Results: Some meconium and transitional stool samples were noted to have a more marked increase in light absorbance as wavelength decreases towards 650 nm, when compared to more mature stools. (elsevier.com)
- Caution is warranted in interpreting GI StO 2 NIRS results in neonates still passing meconium and transitional stools until NIRS-based tissue oximeters to measure GI StO 2 can compensate for the presence of these stool types. (elsevier.com)
- The gastrointestinal tract, still forming, starts to collect sloughed skin and lanugo, as well as hepatic products, forming meconium (stool). (wikidoc.org)
- Your baby's bowels are working now: In fact, that little digestive tract can create meconium, a dark green stool. (enfamil.com)
- Melina is very similar to meconium because it's an extremely solid black or tarry stool. (itsdailymagazine.com)
Neonates4
- Other GI manifestations in neonates include intestinal obstruction at birth and various surgical findings (eg, volvulus, intestinal atresia, perforation, meconium peritonitis). (medscape.com)
- Mazouri A, Fallah R, Saboute M, Taherifard P, Dehghan M. The prognostic value of the level of lactate in umbilical cord blood in predicting complications of neonates with meconium aspiration syndrome. (ijrcog.org)
- We aimed to systematically review and analyse the outcomes of non-endotracheal suctioning (non-ETS) versus ETS in non-vigorous meconium -stained neonates . (bvsalud.org)
- In this study, we aimed to determine the Meconium Aspiration Syndrome in neonates, born between the years 2015 and 2019, in Shahid Mostafa Khomeini and Taleghani Hospitals of Ilam, before and after the NRP protocol change. (ac.ir)
Cystic fibrosis1
- Meconium plug syndrome may result from Hirschsprung disease or cystic fibrosis. (msdmanuals.com)
Neonatal7
- This means, that meconium staining is evidence of neonatal distress, no matter the severity. (dr-efi.com)
- 1 . The initial reason that the meconium appeared - again, meconium staining may indicate certain neonatal distress. (dr-efi.com)
- Thick and granular meconium has been found to have a significant association with an abnormal cord pH and lactate and worst neonatal outcome. (ijrcog.org)
- When, belatedly, expectant management was instead used as the analytically and clinically appropriate comparator, 5 several large observational cohorts demonstrated a lower frequency of cesarean delivery in association with induction of labor, as well as fewer cases of neonatal depression, meconium aspiration, neonatal intensive care unit admission, and perinatal death. (researchgate.net)
- Spontaneous neonatal pneumothorax is associated with aspiration of blood or meconium and birth-related trauma, but can also result from positive pressure ventilation. (bmj.com)
- El coeficiente de mortalidad neonatal disminuyó en 2014 (3,79) y 2015 (2,28). (bvsalud.org)
- In the setting of live birth, isolation of L. monocytogenes from a non-sterile neonatal specimen (e.g., meconium, tracheal aspirate, but not products of conception) collected within 48 hours of delivery. (cdc.gov)
Condition is called meconium aspirati2
- As far as I can understand this condition is called meconium aspiration syndrome (MAS). (ndtv.com)
- When this occurs, the condition is called meconium aspiration syndrome. (cerebralpalsyguidance.com)
Intestinal4
- Meconium plug syndrome is blockage of the large intestine with thick intestinal contents (meconium). (msdmanuals.com)
- Intestinal obstruction caused by congealed MECONIUM in the distal ILEUM and CECUM. (ouhsc.edu)
- Meconium is a viscous green-black substance that consists of denuded intestinal epithelial cells, ingested lanugo hair, mucus, digestive enzymes, bile acids, and water. (medscape.com)
- 2013). Meconium is the first intestinal discharge of newborns, which consists of a viscous, sticky, dark green substance. (cyberleninka.org)
Newborns4
- Newborns expel meconium at or shortly after birth. (msdmanuals.com)
- The prospective, population-based cohort study collected the meconium of 212 consecutive newborns, analysed its microbiome and evaluated whether there is an association with subsequent infantile colic. (hipp.com)
- No significant qualitative differences were found in the steroid composition of meconium from male and female newborns. (houstonmethodist.org)
- Newborns should have at least one bowel movement, larger than a quarter size, each day for their first and second days after birth.Their first stools, called meconium, are dark green to almost black in color. (newmomcollective.com)
Baby's5
- The baby's anal sphincter will begin to relax and release meconium. (cerebralpalsyguidance.com)
- Suction will be used to remove the meconium from the baby's airway before he takes his first breath, in order to prevent it being aspirated into the lungs. (gynob.com)
- They get swallowed by the fetus along with other secretions and lodge in the baby's bowels - where they'll become the child's first BM, a tarry waste called meconium. (smartdraw.com)
- Seeing the meconium in diapers indicates that the baby's digestive system is operating normally. (itsdailymagazine.com)
- Ursodeoxycholic acid has been shown in prior studies to have beneficial effects for the fetus and the pregnancy including reducing risk of meconium staining, protecting the baby's heart against changes induced by bile acids, restoring the placenta's ability to transport bile acids away from the baby, and protecting cells from damage due to bile acids. (icpcare.org)
Similar to meconium1
- is similar to meconium plug syndrome except that it is the small intestine that is blocked by meconium. (msdmanuals.com)
Inhale the meconium2
- When a baby stools while still in the womb, it can inhale the meconium when taking the first breaths. (cerebralpalsyguidance.com)
- It was my water that just had broken I was told that Emma was stressing and had gone poop in my belly which was not a good thing because she could inhale the meconium (first poop) and that could be dangerous. (blogspot.com)
Utero3
- Studies have shown that the meconium already contains a diverse microbiome and that colonisation of the infant intestine begins in utero. (hipp.com)
- Occasionally, meconium is passed in utero, which indicates the baby is in distress. (gynob.com)
- I pushed for two hours before she finally graced the world with her beautiful soul, covered in her own meconium from a bowel movement she had while in utero. (amberjeromenorrgard.com)
Bowel4
- The first bowel movement a baby has is called meconium. (medlineplus.gov)
- At this time in his growth, your baby begins to produce meconium, his first bowel movement. (gynob.com)
- If your baby continues to have meconium bowel movements when he is 4 days old, see a healthcare provider to make sure baby is taking in enough milk. (newmomcollective.com)
- These bowel movements are brown or green in color and less sticky than the meconium. (newmomcollective.com)
Pneumonia1
- Long-term respiratory complications from meconium aspiration can manifest as an oxygen requirement, severe asthma-like symptoms, poor growth, and frequent cases of viral or bacterial pneumonia. (cerebralpalsyguidance.com)
Gestational age1
- Meconium-stained AF rates are different among races and across gestational age, and overall risk of adverse outcomes in meconium stained AF is low. (qxmd.com)
Prenatal exposure1
- 13. Hutson J, Magri R, Suarez H, Miguez H, Gareri J, Koren G. High prevalence of prenatal exposure to alcohol and other drugs of abuse in Uruguay as determined by meconium analysis. (jptcp.com)
Term meconium2
- If you are reading this, you probably just had (or soon to have) a baby and have heard this term Meconium. (dr-efi.com)
- The term meconium is derived from the Greek word mekonion , which means poppy juice or opium, presumably either because of its tarry appearance or because of Aristotle's belief that it induced sleep in the fetus. (medscape.com)
Maternal3
- Meconium contained high levels of toxic heavy metals and trace elements compared to cord blood and maternal blood. (who.int)
- Many perinatal risk factors have been associated with meconium aspiration, including placental insufficiency, maternal hypertension, maternal diabetes mellitus , preeclampsia , oligohydramnios , and maternal tobacco use. (medscape.com)
- Increased sensitivity of the hair against maternal meconium in detecting exposure to cannabis. (springer.com)
Weeks of gestat1
- The predictors of meconium-stained AF from 37 weeks of gestation onward were determined using multiple logistic regression. (qxmd.com)
Congenital2
- This is typically seen as a reflection of birth events (delivery after 40 weeks gestation, meconium aspiration syndrome, infection such as Group B Streptococcus) or with congenital heart lesions, which the extra blood flow through the pulmonary circulation can stress the pulmonary blood vessels (premature closure of blood vessels, pulmonary venous abnormalities). (phassociation.org)
- Congenital condylomataacuminata with meconium staining of amniotic fluidand fetal hydrocephalus: case report. (bvsalud.org)
Endotracheal2
- Then endotracheal suctioning can be done to remove as much meconium as possible from the airway. (cerebralpalsyguidance.com)
- Comparison of suction rates between a standard Yankauer and make-shift large bore suction catheters using a meconium aspirator and various sized endotracheal tubes. (tactical-medicine.com)
Methods1
- Analytical methods were evaluated for measuring cocaine (CO), benzoylecgonine (BE), and ecgonine methyl ester (EME) in urine and methanolic extracts from meconium and diapers by isotope dilution gas chromatography/mass spectrometry (GC/MS). Volatile derivatives of the extracted drugs were generated before GC/MS analysis. (unboundmedicine.com)
Greenish black1
- Meconium is thick, greenish black, and sticky. (medlineplus.gov)
Fetus3
- Meconium is formed by the fetus as early as the 12th week of gestation, accumulates throughout pregnancy, and is normally excreted after birth by the infant. (bmj.com)
- Meconium is therefore a repository of many of the xenobiotics that the fetus is exposed to throughout pregnancy and its analysis has consequently been used for the detection of fetal exposure to illicit drugs. (bmj.com)
- Postterm fetus may pass the meconium physiologically. (medscape.com)
Respiratory Distress1
- Given that delivery was normal and there's no respiratory distress of any kind after birth, usually the meconium staining bears no significance for the rest of life. (dr-efi.com)
Specimen3
- Collect entire random meconium specimen. (testcatalog.org)
- Prevent the meconium specimen from coming in contact with ANY ethanol-based liquids or vapors at ANY TIME previous to, and during, the collection process. (usdtl.com)
- We will not test the meconium for FAEE if the specimen was collected more than 18 hours after birth. (usdtl.com)
Outcomes1
- The aim of this study was to analyse and compare the mode of delivery, cord blood parameters and fetal outcomes in cases diagnosed with different degrees of meconium staining liquor. (ijrcog.org)
Aspirator1
- Meconium aspirator eliminates mouth suctioning. (medpick.in)
Peritonitis2
Fetal hypoxia2
- Intrauterine meconium passage has been linked to fetal hypoxia and is associated with fetal acidosis, abnormal fetal heart tracings, and low Apgar scores. (medscape.com)
- More blacks (17.9%, 95% CI 17.3-18.4) and South Asians (11.8%, 95% CI 11.5-12.1) with good outcome and no risk factors for fetal hypoxia had meconium-stained AF than did whites (11.2%, 95% CI 11.1-11.4). (qxmd.com)
Thick3
- If the meconium is abnormally thick or tarlike, it can block the large intestine (colon). (msdmanuals.com)
- In meconium plug syndrome, the colon is completely blocked with thick meconium. (msdmanuals.com)
- Meconium is a thick green-black odorant substance, which is produced in the embryo's gut at the 12th week of gestation, and then stored in the colon throughout the pregnancy. (ac.ir)
Hypoxia1
- Intrauterine gasping, resulting in aspiration of meconium, has been demonstrated in animal models exposed to hypoxia. (medscape.com)
Pathophysiology1
- Pathophysiology of meconium aspiration. (medscape.com)
Stools1
- Discussion: Meconium and green colored transitional stools demonstrate a light absorbance spectra that may interfere with NIRS GI measurements, possibly due to their higher biliverdin content, which exhibits a broad spectral absorption peak at 660 nm. (elsevier.com)
Outcome2
- Correlation of umbilical blood pH and outcome in meconium stained deliveries. (ijrcog.org)
- The primary outcome was the incidence of meconium aspiration syndrome (MAS). (bvsalud.org)
Symptoms1
- P24.01 is a valid billable ICD-10 diagnosis code for Meconium aspiration with respiratory symptoms . (icd10coded.com)
Womb2
- It is meconium that is found in the intestines of your baby during the womb. (itsdailymagazine.com)
- Meconium refers to the expulsion of womb fluids out of the digestive system of your baby The presence of melena can be a sign of bleeding within the digestive tract. (itsdailymagazine.com)
Persistent1
- [ 12 ] These cases probably represent a combination of meconium aspiration and persistent pulmonary hypertension of the newborn (PPHN). (medscape.com)
Babies1
- Babies who are severely affected by MAS will have a chemical irritation of the airways caused by the meconium. (cerebralpalsyguidance.com)
Metabolites2
- Cocaine and metabolites were extracted from wet but meconium-free diapers into methanol, which was evaporated before reconstituting in drug-free urine and extraction on a solid phase column. (unboundmedicine.com)
- Unless precautions are taken to prevent extracorporeal contamination of meconium with urine, concentrations of CO and metabolites in meconium may be substantially augmented by contamination with urine. (unboundmedicine.com)
Amnioinfusion2
- Amnioinfusion for meconium-stained liquor in labour: Cochrane systematic review is a topic covered in the Cochrane Abstracts . (unboundmedicine.com)
- Cochrane Abstracts , Evidence Central , evidence.unboundmedicine.com/evidence/view/Cochrane/431530/all/Amnioinfusion_for_meconium_stained_liquor_in_labour:_Cochrane_systematic_review. (unboundmedicine.com)
Urine4
- Methanolic extracts from meconium and diapers were reconstituted in drug-free urine and treated as above. (unboundmedicine.com)
- Quantitative results were linear from 25 to 10,000 ng per g of meconium and 25 to 5,000 ng per mL of urine. (unboundmedicine.com)
- Day-to-day precision varied from eight percent (CV) for BE in refrigerated or frozen urine to 34 percent for EME in refrigerated meconium. (unboundmedicine.com)
- The CO, BE, and EME were detected in previously drug-free meconium after portions were deposited in a diaper which was wet with drug-positive urine. (unboundmedicine.com)
Vaginal1
- Independent predictors of meconium-stained AF included being black (odds ratio [OR] 8.4, 95% CI 2.4-28.8), vaginal breech delivery (OR 4.7, 95% CI 4.2-5.3), being South Asian (OR 3.3, 95% CI 1.3-8.3), and being in an advancing week of gestation (OR 1.39, 95% CI 1.38-1.40). (qxmd.com)
Exposure9
- Fatty acid ethyl esters (FAEEs) in meconium are validated biomarkers of heavy fetal alcohol exposure that may potentially be used clinically for identifying children at risk for alcohol-related disabilities. (jptcp.com)
- Fatty acid ethyl esters in meconium: are they biomarkers of fetal alcohol exposure and effect? (jptcp.com)
- 12. Gareri J, Lynn H, Handley M, Rao C, Koren G. Prevalence of fetal ethanol exposure in a regional population-based sample by meconium analysis of fatty acid ethyl esters. (jptcp.com)
- Is meconium exposure associated with autism spectrum disorders in children? (e-cep.org)
- The results differ among published studies regarding exposure to meconium and the risk of developing autism spectrum disorders (ASDs). (e-cep.org)
- The present study pooled all of the epidemiologic studies retrieved from broader databases on the association between meconium exposure and risk of developing ASD in children. (e-cep.org)
- Meconium exposure was weakly associated with an increased risk of ASD. (e-cep.org)
- However, more evidence based on large prospective cohort studies is required to provide conclusive evidence about whether meconium exposure is associated with an increased risk of ASD development. (e-cep.org)
- Meconium exposure is weakly associated with an increased risk of autism spectrum disorder (ASD) development in children. (e-cep.org)
Birth2
- Factors related to the delivery room experience may be associated with meconium aspiration syndrome, birth weight, and labor time. (hindawi.com)
- The only way to tell for sure if meconium has been passed prior to delivery is at birth, when the sac breaks. (gynob.com)
Lungs1
- it may reflect a more significant meconium load or the aspiration of thicker meconium into the lungs. (medscape.com)