Access to Information: Individual's rights to obtain and use information collected or generated by others.Acupuncture Therapy: Treatment of disease by inserting needles along specific pathways or meridians. The placement varies with the disease being treated. It is sometimes used in conjunction with heat, moxibustion, acupressure, or electric stimulation.Acupuncture: The occupational discipline of the traditional Chinese methods of ACUPUNCTURE THERAPY for treating disease by inserting needles along specific pathways or meridians.Journal Impact Factor: A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.History, Ancient: The period of history before 500 of the common era.Complementary Therapies: Therapeutic practices which are not currently considered an integral part of conventional allopathic medical practice. They may lack biomedical explanations but as they become better researched some (PHYSICAL THERAPY MODALITIES; DIET; ACUPUNCTURE) become widely accepted whereas others (humors, radium therapy) quietly fade away, yet are important historical footnotes. Therapies are termed as Complementary when used in addition to conventional treatments and as Alternative when used instead of conventional treatment.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Strongylocentrotus: A genus of SEA URCHINS in the family Strongylocentrotidae. They possess more than three pore pairs per ambulacral plate. The species STRONGYLOCENTROTUS PURPURATUS is commonly used for research.Population Density: Number of individuals in a population relative to space.Population Dynamics: The pattern of any process, or the interrelationship of phenomena, which affects growth or change within a population.Population Growth: Increase, over a specific period of time, in the number of individuals living in a country or region.Reproduction: The total process by which organisms produce offspring. (Stedman, 25th ed)Predatory Behavior: Instinctual behavior pattern in which food is obtained by killing and consuming other species.Sex Ratio: The number of males per 100 females.Lithium: An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of lithium are used in treating BIPOLAR DISORDER.Lithium Compounds: Inorganic compounds that contain lithium as an integral part of the molecule.Lithium Chloride: A salt of lithium that has been used experimentally as an immunomodulator.Morphogenesis: The development of anatomical structures to create the form of a single- or multi-cell organism. Morphogenesis provides form changes of a part, parts, or the whole organism.Lithium Carbonate: A lithium salt, classified as a mood-stabilizing agent. Lithium ion alters the metabolism of BIOGENIC MONOAMINES in the CENTRAL NERVOUS SYSTEM, and affects multiple neurotransmission systems.Glycogen Synthase Kinase 3: A glycogen synthase kinase that was originally described as a key enzyme involved in glycogen metabolism. It regulates a diverse array of functions such as CELL DIVISION, microtubule function and APOPTOSIS.Antimanic Agents: Agents that are used to treat bipolar disorders or mania associated with other affective disorders.MoscowAnti-Arrhythmia Agents: Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.Lasers: An optical source that emits photons in a coherent beam. Light Amplification by Stimulated Emission of Radiation (LASER) is brought about using devices that transform light of varying frequencies into a single intense, nearly nondivergent beam of monochromatic radiation. Lasers operate in the infrared, visible, ultraviolet, or X-ray regions of the spectrum.Laser Therapy, Low-Level: Treatment using irradiation with LASER light of low power intensity so that the effects are not due to heat, as they are in LASER THERAPY.Lasers, Solid-State: Lasers which use a solid, as opposed to a liquid or gas, as the lasing medium. Common materials used are crystals, such as YAG (YTTRIUM aluminum garnet); alexandrite; and CORUNDUM, doped with a rare earth element such as a NEODYMIUM; ERBIUM; or HOLMIUM. The output is sometimes additionally modified by addition of non-linear optical materials such as potassium titanyl phosphate crystal, which for example is used with neodymium YAG lasers to convert the output light to the visible range.Lasers, Semiconductor: Lasers with a semiconductor diode as the active medium. Diode lasers transform electric energy to light using the same principle as a light-emitting diode (LED), but with internal reflection capability, thus forming a resonator where a stimulated light can reflect back and forth, allowing only a certain wavelength to be emitted. The emission of a given device is determined by the active compound used (e.g., gallium arsenide crystals doped with aluminum or indium). Typical wavelengths are 810, 1,060 and 1,300 nm. (From UMDNS, 2005)RussiaWine: Fermented juice of fresh grapes or of other fruit or plant products used as a beverage.Longevity: The normal length of time of an organism's life.Caloric Restriction: Reduction in caloric intake without reduction in adequate nutrition. In experimental animals, caloric restriction has been shown to extend lifespan and enhance other physiological variables.Protein Engineering: Procedures by which protein structure and function are changed or created in vitro by altering existing or synthesizing new structural genes that direct the synthesis of proteins with sought-after properties. Such procedures may include the design of MOLECULAR MODELS of proteins using COMPUTER GRAPHICS or other molecular modeling techniques; site-specific mutagenesis (MUTAGENESIS, SITE-SPECIFIC) of existing genes; and DIRECTED MOLECULAR EVOLUTION techniques to create new genes.Stilbenes: Organic compounds that contain 1,2-diphenylethylene as a functional group.Williams Syndrome: A disorder caused by hemizygous microdeletion of about 28 genes on chromosome 7q11.23, including the ELASTIN gene. Clinical manifestations include SUPRAVALVULAR AORTIC STENOSIS; MENTAL RETARDATION; elfin facies; impaired visuospatial constructive abilities; and transient HYPERCALCEMIA in infancy. The condition affects both sexes, with onset at birth or in early infancy.Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA.Myxedema: A condition characterized by a dry, waxy type of swelling (EDEMA) with abnormal deposits of MUCOPOLYSACCHARIDES in the SKIN and other tissues. It is caused by a deficiency of THYROID HORMONES. The skin becomes puffy around the eyes and on the cheeks. The face is dull and expressionless with thickened nose and lips.Thyroid Hormones: Natural hormones secreted by the THYROID GLAND, such as THYROXINE, and their synthetic analogs.Thyroid Gland: A highly vascularized endocrine gland consisting of two lobes joined by a thin band of tissue with one lobe on each side of the TRACHEA. It secretes THYROID HORMONES from the follicular cells and CALCITONIN from the parafollicular cells thereby regulating METABOLISM and CALCIUM level in blood, respectively.Hyperthyroidism: Hypersecretion of THYROID HORMONES from the THYROID GLAND. Elevated levels of thyroid hormones increase BASAL METABOLIC RATE.Congenital Hypothyroidism: A condition in infancy or early childhood due to an in-utero deficiency of THYROID HORMONES that can be caused by genetic or environmental factors, such as thyroid dysgenesis or HYPOTHYROIDISM in infants of mothers treated with THIOURACIL during pregnancy. Endemic cretinism is the result of iodine deficiency. Clinical symptoms include severe MENTAL RETARDATION, impaired skeletal development, short stature, and MYXEDEMA.Graves Disease: A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).Receptors, Cannabinoid: A class of G-protein-coupled receptors that are specific for CANNABINOIDS such as those derived from CANNABIS. They also bind a structurally distinct class of endogenous factors referred to as ENDOCANNABINOIDS. The receptor class may play a role in modulating the release of signaling molecules such as NEUROTRANSMITTERS and CYTOKINES.Receptor, Cannabinoid, CB1: A subclass of cannabinoid receptor found primarily on central and peripheral NEURONS where it may play a role modulating NEUROTRANSMITTER release.Cannabinoids: Compounds having the cannabinoid structure. They were originally extracted from Cannabis sativa L. The most pharmacologically active constituents are TETRAHYDROCANNABINOL; CANNABINOL; and CANNABIDIOL.Receptor, Cannabinoid, CB2: A subclass of cannabinoid receptor found primarily on immune cells where it may play a role modulating release of CYTOKINES.Long-Term Potentiation: A persistent increase in synaptic efficacy, usually induced by appropriate activation of the same synapses. The phenomenological properties of long-term potentiation suggest that it may be a cellular mechanism of learning and memory.Cannabinoid Receptor Agonists: Compounds that interact with and stimulate the activity of CANNABINOID RECEPTORS.Dronabinol: A psychoactive compound extracted from the resin of Cannabis sativa (marihuana, hashish). The isomer delta-9-tetrahydrocannabinol (THC) is considered the most active form, producing characteristic mood and perceptual changes associated with this compound.Copyright: It is a form of protection provided by law. In the United States this protection is granted to authors of original works of authorship, including literary, dramatic, musical, artistic, and certain other intellectual works. This protection is available to both published and unpublished works. (from Circular of the United States Copyright Office, 6/30/2008)Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)Adaptation, Physiological: The non-genetic biological changes of an organism in response to challenges in its ENVIRONMENT.Software: Sequential operating programs and data which instruct the functioning of a digital computer.Myocytes, Cardiac: Striated muscle cells found in the heart. They are derived from cardiac myoblasts (MYOBLASTS, CARDIAC).Editorial Policies: The guidelines and policy statements set forth by the editor(s) or editorial board of a publication.Algorithms: A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.
2 Mechanism of action. *3 Adverse effects. *4 References. *5 External links ... Adverse effects. The use of romidepsin is uniformly associated with adverse effects. In clinical trials, the most ... Mechanism of action. Romidepsin acts as a prodrug with the disulfide bond undergoing reduction within the cell to release ... The first total synthesis of romidepsin was accomplished by Harvard researchers and published in 1996. Its mechanism of ...
2 Side effects. *3 Pharmacology *3.1 Mechanism of action. *4 Society and culture *4.1 Trade names ... Side effects. The most common adverse effects are diarrhea (4.8%), nausea and vomiting (3.6%), injection-site ... Mechanism of action. Meropenem is bactericidal except against Listeria monocytogenes, where it is bacteriostatic. It ... "Meropenem side effects - from FDA reports". eHealthMe.. *^ Margolin, L (2004). "Impaired rehabilitation secondary to muscle ...
Mechanism of action. See also: Adrenergic receptor. Physiologic responses to epinephrine by organ Organ Effects ... Common side effects include shakiness, anxiety, and sweating. A fast heart rate and high blood pressure may occur. ... Adverse effects. Adverse reactions to adrenaline include palpitations, tachycardia, arrhythmia, anxiety, panic attack, ... Together, these effects lead to increased blood glucose and fatty acids, providing substrates for energy production within ...
Side effects. Rifaximin has few side effects. Side effects are generally mild and uncommon; this is largely because ... Mechanism of action. Rifaximin interferes with transcription by binding to the β-subunit of bacterial RNA polymerase. ... People are more compliant and satisfied to take this medication than any other due to minimal side effects, prolonged remission ... It has minimal side effects, prevents reoccurring encephalopathy, and is associated with high patient satisfaction. ...
2 Adverse effects. *3 Mechanism of Action. *4 History. *5 Multiple sclerosis *5.1 Efficacy ... Mechanism of Action. As a purine analogue, it is taken up into rapidly proliferating cells like lymphocytes to be ... Adverse effects. Injectable cladribine suppresses the body's ability to make new lymphocytes, natural killer cells and ... Although cladribine is selective for B cells, the long term suppression of memory B cells, which may contribute to its effect ...
2 Adverse effects. *3 Mechanism of action. *4 See also. *5 References ... Adverse effects. Apart from side effects like altered estrogen levels and liver damage, many antifungal medicines can ... As a consequence, many antifungal drugs cause side-effects. Some of these side-effects can be life-threatening if the drugs are ... Mechanism of action. Antifungals work by exploiting differences between mammalian and fungal cells to kill the fungal ...
Mechanisms. The Overhauser effect. DNP was first realized using the concept of the Overhauser effect, which is the ... it has been demonstrated that the Cross-Effect mechanism is different in the Static and MAS case. The Cross Effect is the ... mechanisms for the microwave-driven DNP processes are categorized into the Overhauser effect (OE), the solid-effect (SE), the ... The solid effect. The simplest spin system exhibiting the SE DNP mechanism is an electron-nucleus spin pair. The ...
Mechanism of effects. Skeletal muscle. Resistance training and subsequent consumption of a protein-rich meal ... The neurobiological effects of physical exercise are numerous and involve a wide range of interrelated effects on brain ... Moderators of this effect were also examined. Results demonstrated a moderate effect size for increases in BDNF following a ... Interestingly, some symptoms of OT are related to beta-endorphin (beta-end(1-31)) effects. Some of its effects, such as ...
Mechanisms of action. Choleretic effects. Primary bile acids are produced by the liver and stored in the gall ... Anti-inflammatory effects. Ursodeoxycholic acid has been shown to exert anti-inflammatory and protective effects in human ... Bacterial conversion of UDCA to chenodeoxycholic acid may be the mechanism for this side effect. Right upper quadrant abdominal ... Adverse effects. Diarrhea was the most frequent adverse event seen in trial of UDCA in gallstone dissolution, occurring ...
3 Side effects. *4 Mechanism of action. *5 Pharmacokinetics. *6 Approval. *7 References ... Mechanism of action. Prucalopride, a first in class dihydro-benzofuran-carboxamide, is a selective, high affinity ... Side effects. Prucalopride has been given orally to ~2700 patients with chronic constipation in controlled clinical ... The observed effects are exerted via highly selective action on 5-HT4 receptors: prucalopride has ,150-fold higher affinity ...
Triptans and CNS side effects: pharmacokinetic and metabolic mechanisms. DW Dodick et al. Cephalalgia. 2004 Jun;24(6):417-24 ... Side effects. Almotriptan has proved to have an adverse effects profile similar to placebo when used following the ... Mechanism of action. Further information: Serotonin receptor agonist and Triptan § Mechanism_of_action ... Almotriptan has similar efficacy as a standard dose of sumatriptan, another triptan drug, and fewer adverse effects. ...
Mechanisms. Losartan works by blocking the effects of angiotensin II by preventing it from binding to the angiotensin I ... Side Effects. Common side effects include dizziness, headache, back pain, rash, fever, diarrhea, cough, and upper ... Common side effects include dizziness, back pain, and upper respiratory tract infections. Serious side effects may include ... 2] Serious side effects may include low blood pressure, kidney problems, allergic reactions, and electrolyte problems. ...
Side effects include itching, chills, stomach ache, and red rash. Mechanism of action. Spectinomycin binds to the 30S ... Common side effects include pain at the area of injection, rash, nausea, fever, and trouble sleeping. Severe allergic ... Spectinomycin is mainly produced by organisms as a defence mechanism against predators. ...
2 Adverse effects. *3 Mechanism of action. *4 Compendial status. *5 References ... Side effects include diarrhea, nausea, and allergic reactions including anaphylaxis. It is not recommended in those with a ... Mechanism of action. It exerts a bactericidal action against penicillin-sensitive microorganisms during the stage of ... Adverse effects. Further information: Penicillin drug reaction. Phenoxymethylpenicillin is usually well tolerated but may ...
The pharmaceutical company also reports serious allergic reaction as a possible side effect. More common side effects are upper ... Mechanism of action. Ustekinumab (CNTO 1275) is designed to interfere with the triggering of the body's inflammatory ... Adverse effects. According to information provided by Centocor, maker of one medication based on ustekinumab, their ... version of the drug is associated with several types of serious adverse effects. These include an increased risk of infection, ...
1.1.1 Immunosuppressive mechanism. *1.1.2 Anti-inflammatory effects. *1.2 Cytostatics *1.2.1 Alkylating agents ... Side effects. A common side-effect of many immunosuppressive drugs is immunodeficiency, because the majority of them act ... S Roy; HH Loh (1996). "Effects of opioids on the immune system". Neurochem. Res. 21 (11): 1375-1386. doi:10.1007/BF02532379. ... Immunosuppressive mechanism. Glucocorticoids suppress the cell-mediated immunity. They act by inhibiting genes that code ...
1.1 Immunosuppressive mechanism. *1.2 Anti-inflammatory effects. *2 Cytostatics *2.1 Alkylating agents ... Immunosuppressive mechanism. Glucocorticoids suppress the cell-mediated immunity. They act by inhibiting genes that code ... Anti-inflammatory effects. Glucocorticoids influence all types of inflammatory events, no matter their cause. They induce ... TNF or the effects of TNF are also suppressed by various natural compounds, including curcumin (an ingredient in turmeric) and ...
3 Adverse effects. *4 Mechanism of action. *5 History. *6 See also ... Adverse effects. The solution used for irrigation should be distilled, sterile or previously boiled due to the risks ... Mechanism of action. Saline solutions used in nasal irrigation reduce inflammation through osmosis. Swelling is a major ... The mechanism of action is actual flushing of the allergens from the nasal and sinus passages with large volume saline ...
4.1.5 Mechanism of action in endometriosis. *4.1.6 Effects in men ... Effects in men. In men, danazol has been found to inhibit ... Side effects. See also: Anabolic steroid § Adverse effects. Androgenic side effects are of concern, as some women taking ... Mechanism of action in endometriosis. Because danazol reduces estrogen production and levels, it has functional ... The use of danazol is limited by masculinizing side effects such as acne, excessive hair growth, and voice deepening. ...
2 Side effects. *3 Mechanism of action. *4 Society and culture *4.1 Generic equivalents ... Side effects. The common side effects of this combination are those of its individual drugs. For instance, the use of ... Common side effects include thrush, headache, and cough. Serious side effects may include worsening asthma, anaphylaxis, ... Mechanism of action. Fluticasone/salmeterol contains fluticasone propionate a synthetic corticosteroid and salmeterol a ...
Mechanism of action. The drug is an anti-inflammatory, antiallergic immunomodulator. ... Adverse effects. Amlexanox may cause a slightly painful stinging or burning sensation, nausea or diarrhea. ... Its mechanism of action is not well-determined, but it might inhibit inflammation by inhibiting the release of histamine and ...
2 Side effects. *3 Mechanism of action. *4 Available forms. *5 "Blood" in the stool ... Side effects. Side effects include diarrhea, vaginal infections or inflammation, nausea, headache, and abdominal pain."[8 ... Mechanism of action. Main article: Cephalosporin. Available forms. Cefdinir is administered orally. It is available ...
5 Adverse effects. *6 Mechanism of action. *7 References. Approval history. Alosetron was originally approved by the U.S ... Mechanism of action. Alosetron has an antagonist action on the 5-HT3 receptors of the enteric nervous system of the ... Adverse effects. Alosetron was withdrawn in 2000 following the association of alosetron with serious life-threatening ... 2000 owing to the occurrence of serious life-threatening gastrointestinal adverse effects, including 5 deaths and additional ...
3 Adverse effects. *4 Interactions. *5 Mechanism of action. *6 Society and culture *6.1 Names ... Common side effects include chest pain, dizziness, dry mouth, and tingling. Other side effects may include myocardial ... Adverse effects. Frequent adverse effects (incidence less than 10%) are dizziness, drowsiness, asthenia/fatigue, and ... Mechanism of action. Further information: Serotonin receptor agonist and Triptan § Mechanism_of_action ...
3 Side effects *3.1 Interactions. *4 Mechanism of action *4.1 Hyperkalemia. *4.2 Clostridium difficile associated diarrhea ( ... Mechanism of action. Hyperkalemia. Polystyrene sulfonates release sodium or calcium ions in the stomach in exchange ... Side effects. Intestinal disturbances are common, including loss of appetite, nausea, vomiting, and constipation. In rare ... The net effect is lowering the amount of potassium available for absorption into the blood and increasing the amount that is ...
Oettel M, Schillinger E (6 December 2012). Estrogens and Antiestrogens I: Physiology and Mechanisms of Action of Estrogens and ... Footnotes: a = Synthetic (i.e., not endogenous). b = Atypical uterotrophic effect which plateaus within 48 hours (estradiol's ...
Rüegg, J.C., Schädler, M., Steiger, G.J. et al. Effects of inorganic phosphate on the contractile mechanism. Pflugers Arch. 325 ... Effects of inorganic phosphate on the contractile mechanism. *J. C. Rüegg1. , ... The effect of sinusoidal changes of length on a beetle flight muscle. Proc. roy. Soc. B,152, 311 (1960). ... Taylor, E. W., Lymn, R. W., Moll, G.: Myosin product complex and its effect on the steady rate of nucleoside triphosphate ...
Mechanisms behind climate effects on zooplankton. Kristina Ø. Kvile, Øystein Langangen, Irina Prokopchuk, Nils C. Stenseth, ... Mechanisms behind climate effects on zooplankton. Kristina Ø. Kvile, Øystein Langangen, Irina Prokopchuk, Nils C. Stenseth, ... Disentangling the mechanisms behind climate effects on zooplankton Message Subject (Your Name) has sent you a message from PNAS ... Disentangling the mechanisms behind climate effects on zooplankton. Kristina Ø. Kvile, Øystein Langangen, Irina Prokopchuk, ...
... Wei-Bo Zhang,1 Andrew Wu,2 Gerhard Litscher,3 and ... The effect mechanism was analyzed according to the relationship between the meridian sinew and the fluid meridian channels in ... In this special issue, we have provided an overview of the majority of studies related to the effects and mechanisms of ... Four papers focused on the mechanism of acupuncture. W.-B. Zhang et al. studied the mechanism of acupuncture in channel ...
... 912379. A single cylinder engine was used to ... Citation: Kim, C., Cheng, S., and Majorski, S., "Engine Combustion Chamber Deposits: Fuel Effects and Mechanisms of Formation ...
... the mechanisms in practice. It begins with reproductive mechanisms, including fertilization efficiency in broadcast spawners, ... For each mechanism, the chapter discusses how it works in theory, and then presents current evidence for, and examples of, ... Finally, the chapter discusses Allee effects in social and cooperative species, where group size is important for both ... It then moves on to mechanisms related to survival: environmental conditioning and particularly predation, both via the ...
... Zhao-Yu Guo,1,2 Zhuo-Yang Zhang,1 Jia- ...
A molecular mechanism for the effect of lithium on development. P S Klein and D A Melton ... Lithium, one of the most effective drugs for the treatment of bipolar (manic-depressive) disorder, also has dramatic effects on ... How lithium exerts these diverse effects is unclear, but the favored hypothesis is that lithium acts through inhibition of ... These observations help explain the effect of lithium on cell-fate determination and could provide insights into the ...
N. I. Pirogov Second Moscow Medical Institute. (Presented by Academician of the Academy of Medical Sciences B. T. Velichkovskii.) Translated from Byulleten Éksperimentalnoi Biologii i Meditsiny, Vol. 113, No. 5, pp. 460-462, May, 1992. ...
Neurobiological Mechanisms of the Placebo Effect. Fabrizio Benedetti, Helen S. Mayberg, Tor D. Wager, Christian S. Stohler, Jon ... Neurobiological Mechanisms of the Placebo Effect. Fabrizio Benedetti, Helen S. Mayberg, Tor D. Wager, Christian S. Stohler, Jon ... Neurobiological Mechanisms of the Placebo Effect. Fabrizio Benedetti, Helen S. Mayberg, Tor D. Wager, Christian S. Stohler and ... Neurobiological Mechanisms of the Placebo Effect Message Subject (Your Name) has forwarded a page to you from Journal of ...
Until now, many of the underlying mechanisms of how the herbs worked remained unknown. In a new study, researchers uncovered ... New study explains the molecular mechanism for the therapeutic effects of cilantro Herbs, including cilantro, have long been ... New study explains the molecular mechanism for the therapeutic effects of cilantro. University of California - Irvine ... Until now, many of the underlying mechanisms of how the herbs worked remained unknown. In a new study, researchers uncovered ...
The SH-SY5Y antiproliferative effect elicited by BJ was not due to a cytotoxic action and it did not induce apoptosis. Instead ... Our data suggest a mechanisms through which BJ can inhibit important molecular pathways related to cancer-associated aggressive ...
... 20.09.2004 ... Resveratrol, a beneficial component of red wine, is thought to contribute to the improved cardiovascular effects associated ... Im Focus: Demonstration of a single molecule piezoelectric effect. Breakthrough provides a new concept of the design of ... "In addition to illuminating the molecular mechanisms of plant evolution, this study has agricultural and nutraceutical ...
Effects of Meditation on Mechanism of Coronary Heart Disease. The safety and scientific validity of this study is the ... Based on these and related data, we propose a randomized, blinded, controlled study of the effects of one CAM practice, the TM ...
Lipid Peroxidation: Inhibition, Effects and Mechanisms. Angel Catalá, Ph.D. (Editor). Facultad de Ciencias Exactas, Universidad ... Home / Shop / Books / Science and Technology / Chemistry / Lipid Peroxidation: Inhibition, Effects and Mechanisms. ... This book presents an overview of lipid peroxidation: inhibition, effects and mechanisms. The topics analyzed, cover a broad ... Kinetics and Mechanism of Inhibited Lipid Autoxidation in Presence of 4-Substituted-Coumarins. Vessela D. Kancheva, Silvia E. ...
... have been showed to induce obesogenic effects which may last over generations. However, the underlying mechanisms are not yet ... The overall results demonstrated that the obesogenic effects of PFOA were resulted from a complex combination of various ... Notably, PFOA exposure provoked significantly different effects in daf-2 nematodes on fat contents, lipid metabolizing enzymes ...
We fill this void by precisely defining a causal mechanism effect of a treatment and the causal effect of a treatment net of ... The definition of our parameters results in an intuitive decomposition of the total effect of a treatment that is useful for ... We offer conditions under which these causal effects can be estimated for the case of a randomly assigned treatment and when ... there seems to be no available framework to estimate the relative importance of different causal mechanisms of a treatment. ...
Rodrigues, M.A.; Gomes, D.A.; Nathanson, M.H. Calcium Signaling in Cholangiocytes: Methods, Mechanisms, and Effects. Int. J. ... "Calcium Signaling in Cholangiocytes: Methods, Mechanisms, and Effects." Int. J. Mol. Sci. 19, no. 12: 3913. ... Calcium Signaling in Cholangiocytes: Methods, Mechanisms, and Effects. Michele Angela Rodrigues 1. ... Calcium Signaling in Cholangiocytes: Methods, Mechanisms, and Effects. International Journal of Molecular Sciences. 2018; 19(12 ...
... Lancet. 2016 Jan 30;387(10017):475-90. doi: ...
... discute lo stato attuale della letteratura statunitense sui meccanismi culturali nella ricerca sui neighborhood effects. In ... culturale dei quartieri svantaggiati che sono esplicitamente integrate nella recente letteratura sui neighborhood effects negli ... Cultural mechanisms in neighborhood effects research in the united states ( Il contributo ... literature on cultural mechanisms in neighborhood effects research. We first define what we mean by neighborhood effects and by ...
Hemostatic effect of hemocoagulase agkistrodon and its mechanism]. Download Prime PubMed App to iPhone, iPad, or Android ... Hemostatic Effect of Hemocoagulase Agkistrodon and Its Mechanism]." Zhongguo Shi Yan Xue Ye Xue Za Zhi, vol. 16, no. 4, 2008, ... Hemostatic Effect of Hemocoagulase Agkistrodon and Its Mechanism]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2008;16(4):883-5. PubMed ... Hemostatic effect of hemocoagulase agkistrodon and its mechanism]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2008;16(4):883-5. ...
Mechanisms of the antitumoural effects of aspirin in the gastrointestinal tract.. Bruno A1, Dovizio M, Tacconelli S, Patrignani ... The finding of aspirin benefit at low-doses used for cardioprevention, locates the antiplatelet effect of aspirin at the centre ... In this scenario, aspirin causes a chemopreventive effect by countering platelet activation which seems to play a role in early ...
... Thyroid Hormone Receptors and Mechanism of Action. Receptors ... The net effect is to alter the ratio toward increased contractility. For additional details on mechanism of action and how ... Physiologic Effects of Thyroid Hormones. It is likely that all cells in the body are targets for thyroid hormones. While not ... The effect of the hormone-receptor complex binding to DNA is to modulate gene expression, either by stimulating or inhibiting ...
The mechanism might be involved the pathway of signaling molecular phospho-ERK1/2, phospho-Thr34 DARPP-32 and AFosB in striatum ... Mechanisms of dopamine D1 receptor-mediated ERK1/2 activation in the parkinsonian striatum and their modulation by metabotropic ... Wang L, Yan D, Xiao H, Sun S, Xu Y. Effects of chitosan-coated levodopa nanoliposomes on behaviour and levels of phosphorylated ... 5) but had no effect on ERK1/2 expression in 6-OHDA-lesioned rats (data not shown). Fluorescence in situ hybridization/immu- ...
Effects of Fluorocompounds on Mechanisms Related to Mitochondrial Phosphate Transfer. By ALAN S. FAIRHURST, ROBERT E. SMITH, ... Effects of Fluorocompounds on Mechanisms Related to Mitochondrial Phosphate Transfer. By ALAN S. FAIRHURST, ROBERT E. SMITH, ... Effects of Fluorocompounds on Mechanisms Related to Mitochondrial Phosphate Transfer. By ALAN S. FAIRHURST, ROBERT E. SMITH, ... Effects of Fluorocompounds on Mechanisms Related to Mitochondrial Phosphate Transfer Message Subject. (Your Name) has forwarded ...
Mechanism of Cannabinoid Effects on Long-Term Potentiation and Depression in Hippocampal CA1 Neurons. Dinah L. Misner and Jane ... Mechanism of Cannabinoid Effects on Long-Term Potentiation and Depression in Hippocampal CA1 Neurons ... Mechanism of Cannabinoid Effects on Long-Term Potentiation and Depression in Hippocampal CA1 Neurons ... Mechanism of Cannabinoid Effects on Long-Term Potentiation and Depression in Hippocampal CA1 Neurons ...
ElucidateTherapeutic effectsBeneficial effectsNeurobiological mechanismsAnti-inflammatoryUnderstand the mechanismsNeurobiology of the placebo effectUnderlyingCardiovascularPathwaysToxicityBiological EffectsProtectiveMethodsBradycardic EffectExposureLiverAntioxidantMetabolicGlucose metabolismLocomotorCellular and molecular mechanismBrain mechanismsAnalgesic effectsPlacebo treatmentPrecise mechanismsBehaviorUnderstandingLipidExperimentalEvaluateAntibacterialExpectationVivoCardiacPlateletDiseasesChronicFormationDemonstrate2018ResultsStatinsDeterminePathwayGastrointestinalContractility
- By combining oceanographic drift models and statistical analyses of field data from 1959 to 1993 and investigating effects across trophic levels, we are able to elucidate pathways by which climate influences zooplankton. (pnas.org)
- This highlights the importance of continued research, particularly in animal models, to elucidate the important underpinnings (e.g., timing of exposure, metabolism, dose) of these complex health outcomes and to identify the biological mechanisms underlying sexual dimorphism in iAs-associated diseases. (springer.com)
- Topics such as mathematical modeling of EMF absorption, Ion Cyclotron Resonance in Biological Systems, thermal and dissipation effects of mobile system radiation, effects on transmission lines and railway radiation, effects on the reproductive capacity of specific insects, on the immune systems, embryos, fetuses, blood parameters and behavior of rats are thoroughly covered as well as health risk assessment and therapeutic effects of EMF. (springer.com)
- This text brings together a series of examinations regarding the effects of electromagnetic fields, with particular reference to mechanism, modelling, biological effects, therapeutic effects, international standards and exposure criteria. (springer.com)
- However, more clinical studies demonstrating the therapeutic effects of Descurainia sophia are still warranted. (medsci.org)
- Previous studies identified the high expression of Card9 in peripheral blood mononuclear cells from patients with aseptic acute pancreatitis (5) and the potential mechanisms of therapeutic effects through siRNA silencing of the Card9 gene (6). (thefreelibrary.com)
- To delineate the effect of melatonin on platelet production, we hypothesize that melatonin has therapeutic effects on thrombocytopenia by promoting megakaryocytopoiesis and enhancing the recovery of platelets via activation of Akt/Erk signaling. (bloodjournal.org)
- We performed a systematic and exhaustive review aimed at analyzing the available data regarding the beneficial effects of secondary metabolites in plants. (techscience.com)
- The beneficial effects of secondary metabolites of medicinal plants in various high incidence disease conditions were also reviewed. (techscience.com)
- Our previous reports and others have demonstrated beneficial effects of statins on endothelial dysfunction and chronic inflammation in CAD. (clinsci.org)
- In addition to lipid-lowering and cardiovascular protective actions, statins may have beneficial effects on insulin sensitivity. (scielo.br)
- Their beneficial effects have been mainly attributed to the reduction of circulating LDL-cholesterol levels and oxidized LDL, and to the increase of collagen content in the plaque matrix (4). (scielo.br)
- Second, we wanted to determine whether the lack of heart rate effect previously seen in normal dogs extends to dogs with heart failure and whether the negative chronotropic responses to LY341311 could mediate potential beneficial effects on myocardial O 2 consumption and cardiac efficiency in the failing heart. (aspetjournals.org)
- Evidence from observational studies suggests beneficial effects of ruminant trans fatty acids (rTFA) on insulin resistance (IR) and type 2 diabetes (T2D). (fil-idf.org)
- However, beneficial effects of rTFA are not always observed in cell, animal, and human studies. (fil-idf.org)
- So far, most of the neurobiological mechanisms underlying this complex phenomenon have been studied in the field of pain and analgesia, although recent investigations have successfully been performed in the immune system, motor disorders, and depression. (jneurosci.org)
- The placebo effect, so far considered a nuisance in clinical research when a new treatment is tested, has now become a target of scientific investigation into a better understanding of the physiological and neurobiological mechanisms that associate a complex mental activity to different functions of the body. (smw.ch)
- Anti-Inflammatory Effects of Lychee (Litchi chinensis Sonn. (scirp.org)
- Nicotinic acid has potent anti-inflammatory effects on human monocytes. (ahajournals.org)
- The heme oxygenase system is among the most critical of the cytoprotective mechanisms activated during cellular stress, exerting antioxidant and anti-inflammatory functions, modulating the cell cycle, and maintaining the microcirculation. (dovepress.com)
- Among the pleiotropic effects of statins, anti-inflammatory properties have been the most investigated (11,12) and their cardiovascular protection has also been attributed to such actions (12, 13). (scielo.br)
- To gain a better understanding of the molecular basis for the anti-inflammatory effects of EP, we compared the pharmacological properties of EP and N -acetyl- l -cysteine (NAC), a well studied scavenger of reactive oxygen species and a precursor for the endogenous antioxidant glutathione (GSH). (aspetjournals.org)
- The anti-inflammatory effects of EP were partially reversed when RAW 264.7 cells were treated with a cell-permeable GSH analog, glutathione ethyl ester. (aspetjournals.org)
- These data support the view that the anti-inflammatory effects of EP are mediated, at least in part, by the ability of EP to deplete cellular GSH stores. (aspetjournals.org)
- The biochemical mechanisms responsible for the salutary anti-inflammatory effects of EP remain to be elucidated. (aspetjournals.org)
- Another potential mechanism to explain the anti-inflammatory effects of EP, however, derives from the recognition that all the members of the NF-κB family of proteins share a characteristic motif with one cysteine and three arginine residues in the DNA-binding region ( Dröge, 2002 ). (aspetjournals.org)
- Butyrate is also known to have anti-inflammatory effects and to trigger signaling in immune cells. (thepoultrysite.com)
- Underlying mechanisms behind observed associations between zooplankton dynamics and climate are often unclear. (pnas.org)
- To address the underlying mechanisms, we include drift modeling results in statistical analyses of survey data, analyze spatial and interannual variability, and investigate effects across trophic levels. (pnas.org)
- Until now, many of the underlying mechanisms of how the herbs worked remained unknown. (eurekalert.org)
- However, the underlying mechanisms are not yet clear. (nih.gov)
- Usually, the terms placebo effect and response are used interchangeably by both clinical researchers, who run clinical trials, and by neuroscientists, who want to understand the underlying mechanisms. (smw.ch)
- In particular, the underlying mechanisms of interaction between EMF and biological systems, and the absorption patterns verification of theoretical models via real world measurement assessment are studied. (springer.com)
- Topical tacrolimus has been used for vitiligo as a common treatment option for more than ten years while the underlying mechanism is still uncertain. (sigmaaldrich.com)
- In view of its potent anti-carcinogenic activity, the need to understand the underlying mechanisms has gained prominence. (mdpi.com)
- A better understanding of the molecular mechanism underlying the effectiveness of statins against atherosclerosis may provide a novel therapeutic agent for the treatment of coronary atherosclerosis. (clinsci.org)
- The Effect and Underlying Mechanism of Melatonin on Platelet Formation and Survival in a Thrombocytopenic Model. (bloodjournal.org)
- However, the actual effects and underlying mechanism of melatonin on megakaryocytopoiesis, and platelet formation/survival have not been formally investigated. (bloodjournal.org)
- The underlying mechanisms may be involved in directly stimulating megakaryocytopoiesis and having anti-apoptotic effect in megakaryocytes via the activation of Akt/Erk signaling. (bloodjournal.org)
- This Funding Opportunity Announcement (FOA) invites innovative research grant applications focused on identifying potential mechanisms and risk factors underlying HIV treatment associated neuropsychiatric symptoms and neurological toxicities experienced by some people living with HIV infection. (nih.gov)
- Effects of long-term fluoride exposure on cognitive ability and the underlying mechanisms: Role of autophagy and its association with apoptosis. (fluoridealert.org)
- In addition, the mechanism underlying the CV responses remained a matter of speculation. (ahajournals.org)
- A look at the mechanisms underlying some of the observations we discussed in week 5, through the study of model organisms. (coursera.org)
- 1,2 The rationale of the present study was to explore the brain mechanisms underlying the modulation of pain perception proper to our clinical hypnotic protocol. (asahq.org)
- The underlying mechanisms for the antioxidative effects of the herb have been investigated in the last two decades. (eurekaselect.com)
- This review summarizes some of the critical studies of the long-term health effects and underlying biological mechanisms related to developmental exposure to arsenic. (springer.com)
- Mechanisms underlying these outcomes are likely complex, and include disrupted key biological pathways with ties to the epigenome. (springer.com)
- Research has and continues to investigate the molecular and epigenetic mechanisms underlying the downward spiral of alcoholism. (wikipedia.org)
- Resveratrol, a beneficial component of red wine, is thought to contribute to the improved cardiovascular effects associated with moderate consumption of red wine. (innovations-report.com)
- Are the beneficial cardiovascular effects of simvastatin and metformin also associated with a hormone-dependent mechanism improving insulin sensitivity? (scielo.br)
- Clinical trials in which statins were used as secondary prevention found the cardiovascular protective effect to be even higher in the subset of type 2 diabetic subjects (6). (scielo.br)
- It is possible that part of the cardiovascular benefits of statins for diabetic subjects may be due to their influence on insulin sensitivity in addition to their classical lipid-lowering effect. (scielo.br)
- Our findings demonstrate credible mechanisms whereby fine particulate matter could trigger acute cardiovascular events and that aspects of exposure location may be an important determinant of the health consequences. (ahajournals.org)
- We summarize the possible effects and acting pathways for the herb involved in several chronic diseases in cardiovascular, respiratory, and nervous systems, as well as potential epigenetic influences. (eurekaselect.com)
- 3-6 Although the precise mechanisms are not yet clear, it has been postulated that flavonoids such as EGCG may act as scavengers of reactive oxygen species, thereby preventing the pathogenesis of cardiovascular disease. (ahajournals.org)
- Notably, PFOA exposure provoked significantly different effects in daf-2 nematodes on fat contents, lipid metabolizing enzymes and even different signaling pathways. (nih.gov)
- The overall results demonstrated that the obesogenic effects of PFOA were resulted from a complex combination of various enzymes and pathways with essential involvement of insulin signaling pathway. (nih.gov)
- Following solar UV radiation, a network of DNA damage response mechanisms triggers a signal transduction cascade to regulate various genome-protection pathways including DNA damage repair, cell cycle control, apoptosis, transcription and chromatin remodeling. (rsc.org)
- There is evidence for the involvement of genes engaged in intracellular signaling (i.e., genes that send messages within a cell), as risk factors for suicide and for a differential effect of clozapine on these crucial complex pathways, in particular, the EGF-MAPK-ERK pathway. (afsp.org)
- Thus, the lifespan and healthspan extending effects of fucoxanthin at the organismal level is associated with differential expression of genes and changes in the activity of molecular pathways. (biomedcentral.com)
- The purpose of this study was to investigate the mechanism of the protective effect of zerumbone on the treatment of chronic gastritis in rats. (spandidos-publications.com)
- Zerumbone has a protective effect on chronic gastritis in rats, which is achieved by improving the antioxidant capacity of gastric mucosal tissues through inhibiting lipid peroxidation. (spandidos-publications.com)
- Melatonin also stimulated the formation of bone marrow CFU-F. Using megakaryocytic cell CHRF-281, we further found that melatonin exerted protective effect on serum-free induced apoptosis of CHRF cells. (bloodjournal.org)
- Our study illustrates how improved understanding of climate effects can be obtained when different datasets and different methods are combined in a unified approach. (pnas.org)
- This study examined the antihypoxia effects of SPM in vivo.Materials and methods: The dried and pulverised of SPM was extracted from root crude drug with 70% ethanol with ultrasound. (medworm.com)
- Methods and Results- Boyden chamber assay was used to examine the effect of catechins on the invasive behavior of SMCs. (ahajournals.org)
- The present thesis address mechanisms and survival effects of stroke both clinically (I-III) and experimentally (IV-V).Methods: Study I) Within a cohort of 2641 consecutive cases, a group of cardiac surgery patients with stroke and evaluated by computed tomography (CT) were studied (n=77). (dissertations.se)
- The effects of aluminum (Al) exposure on glucose metabolism and its mechanism were investigated. (springer.com)
- Developmental exposure to iAs results in early and later life health effects. (springer.com)
- The broad scope of health effects from chronic arsenic exposure: update on a worldwide public health problem. (springer.com)
- Vahter M. Health effects of early life exposure to arsenic. (springer.com)
- An understanding of the mechanisms involved in I/R injury is essential for the design of therapeutic strategies to improve the outcome of liver transplantation. (dovepress.com)
- Orotic acid, nucleotide-pool imbalance, and liver-tumor promotion: a possible mechanism for the mitoinhibitory effects of orotic acid in isolated rat hepatocytes. (biomedsearch.com)
- 1. The effects of varying P co 2 on glucose output and the intracellular concentrations of lactate, pyruvate, phosphoenolpyruvate, 2-phosphoglycerate and 3-phosphoglycerate were studied in the isolated rat liver perfused with differing concentrations of lactate. (portlandpress.com)
- An increased interest in the antioxidant effects of medicinal plants has developed in recent years. (techscience.com)
- Identifying antioxidant compounds present in medicinal plants and elucidating the mechanism by which they prevent oxidation have been the focus of the research community. (techscience.com)
- The origin and source of antioxidant compounds, and the cellular and molecular mechanism by which they exert antioxidant effects, have been reported. (techscience.com)
- This work also investigated the effect of the addition of an antioxidant, Vitamin E (VE) to the material. (lu.se)
- This substance promotes a metabolic acidosis, promoting thus a ergolytic effect during intense efforts. (scielo.br)
- These data indicate that autonomically mediated bradycardia produced by LY341311 contributes to a favorable net metabolic effect on myocardial O 2 utilization in the failing heart while providing inotropic support comparable to a β-receptor-mediated agonist. (aspetjournals.org)
- Scientists are interested in placebo responses because the effects of belief on human experience and behavior provide an entry point for studying internal control of affective, sensory, and peripheral processes. (jneurosci.org)
- Despite the well-known relationship between pulmonary edema and bacterial pneumonia, the behavior of host defense mechanisms against inhaled bacteria in the edematous lung remains unclear. (annals.org)
- To make realistic projections of climate effects on marine ecosystems, there is a need for improved understanding of the mechanisms by which climate affects the different trophic levels. (pnas.org)
- We then draw on other related U.S. literatures from urban studies, cultural sociology, and culture and inequality to suggest some other conceptualizations that may be useful in advancing our understanding of the role of culture in neighborhood effects. (francoangeli.it)
- The understanding of the mechanisms of material degradation, especially in regard to oxidation, is one of the keys to significantly improve the mechanical properties. (lu.se)
- This new understanding of what tDCS does to the brain and its confirmation of tDCS as a learning aid comes in the context of controversy over previous reports that seemed to show no effect on neuron firing rates in cadaver heads, which was generally believed to be the mechanism of interest. (hrl.com)
- Understanding the mechanisms that constrain the invasiveness of introduced animals is essential for managing invasions and for predicting their limits. (biologists.org)
- This idea has been refined and alterations in membrane volume or curvature, membrane disordering, and changes in lipid phase transitions have all been suggested as mechanisms by which EtOH could affect the function of membrane proteins ( 9 ). (jimmunol.org)
- Both compounds inhibited LPS-induced lipid peroxidation, but the two compounds had qualitatively different effects on cellular levels of GSH. (aspetjournals.org)
- Results will be presented of an experimental programme to investigate the effect of specimen size on the tensile strength and failure mechanisms of unnotched and notched carbon fibre laminates. (cam.ac.uk)
- These experimental data explore the mechanism of acupuncture's effect on arrhythmias and are useful for clinical application. (acupuncture.edu)
- Aiming to test non-antibiotic alternative strategies to counter the negative consequences of NE, a research group at the University of Cairo set up experiments to evaluate the effects of butyrate in NE-challenged broilers. (thepoultrysite.com)
- Objective: Evaluate the effects of Progressive Muscle Relaxation on sleep quality and on stress and depression levels of individuals with multiple sclerosis. (bioportfolio.com)
- I. Effects of ppGpp on transcription initiation in vivo and in vitro. (nih.gov)
- Shao Q, Xu J, Guan X, Zhou B, Wei W, Deng R, Li D, Xu X, Zhu H. In vitro and in vivo effects of miRNA-19b/20a/92a on gastric cancer stem cells and the related mechanism. (medsci.org)
- We aimed to analyze the in vitro and in vivo effects of miRNA-19b/20a/92a on gastric cancer stem cells (GCSCs) and the related mechanism. (medsci.org)
- There are many studies documenting its numerous clinical effects in cancer, respiratory, gastrointestinal, and cardiac systems. (medsci.org)
- These patients should be closely monitored for both cardiac and non-cardiac adverse effects. (biomedsearch.com)
- The Effect on Cardiac Output of the Conversion from Atrial Fibrillation to a Normal Sinus Mechanism. (annals.org)
- In this scenario, aspirin causes a chemopreventive effect by countering platelet activation which seems to play a role in early event in GI tumourigenesis. (nih.gov)
- Our results showed that melatonin had a promoting effect on platelet formation and survival in a thrombocytopenic model. (bloodjournal.org)
- 3) To identify the factors that alter platelet function and their effect. (findaphd.com)
- Effects of zerumbone on chronic gastritis remain unclear. (spandidos-publications.com)
- ART has advanced HIV infection to a treatable, chronic disease despite the known side effects which may complicate disease management. (nih.gov)
- Alcoholism is a chronic disease characterized by trouble controlling the consumption of alcohol, dependence (needing to consume more to achieve the same effects), and withdrawal upon rapid cessation of drinking. (wikipedia.org)
- The results demonstrate that cadmium has an androgen-like activity in prostate epithelial cells, and this activity implies a new mechanism for the carcinogenic effect of cadmium in the prostate. (cdc.gov)
- Research has shown that Ginnalin A can demonstrate an anti-metastatic effect by regulating the expression of important genes in metastasis on cancer cell lines. (degruyter.com)
- The results show that both chlorophyll biomass in spring and C. finmarchicus biomass in summer relate positively to a combination of shallow mixed layer depth and increased wind in spring, suggesting that C. finmarchicus biomass in summer is influenced by bottom-up effects of food availability. (pnas.org)
- The definition of our parameters results in an intuitive decomposition of the total effect of a treatment that is useful for policy purposes. (repec.org)
- These results indicate that, under conditions in which plasma glucose, insulin, and glucagon are maintained constant, epinephrine stimulates glucose production and inhibits glucose clearance in man predominantly by beta adrenergic mechanisms. (jci.org)
- We considered that Teslar treatment exerted a structurally regenerative effect on the dermal matrix, based on the results of GeneChip ® Expression Analysis. (mdpi.com)
- Results: The effect of Sorafenib appears most strongly in OCUT-4 cell with BRAF mutation compared with other cell lines. (aacrjournals.org)
- Size effects are important as results from small coupons are often used as the basis for design of large structures. (cam.ac.uk)
- Conclusions- These results indicate that EGCG targets multiple MMP-mediated SMC cellular events and provides a new major mechanism for the SMC invasion through upregulation of TIMP-2 expression to modulate MMP activity. (ahajournals.org)
- These results suggest that distinct mechanisms are involved at different D-tyrosine concentrations and they may be species specific. (rice.edu)
- The net effect is to alter the ratio toward increased contractility. (colostate.edu)
- In anesthetized pigs, we compared the effects of dronedarone to the prototypical I f inhibitor, ivabradine, and the L-type calcium channel antagonist diltiazem on heart rate, mean arterial blood pressure (MAP), and contractility. (wiley.com)
- Dronedarone reduced heart rate without affecting MAP or contractility, effects that differ from L-type calcium channel blockade. (wiley.com)