Mebendazole
Antinematodal Agents
Albendazole
Anthelmintics
Echinococcus
Hookworm Infections
Echinococcosis
Ascariasis
Echinococcosis, Hepatic
Pyrvinium Compounds
Ascaris lumbricoides
Enterobiasis
Angiostrongylus cantonensis
Intestinal Diseases, Parasitic
Echinococcosis, Pulmonary
Levamisole
Pyrantel
Effect of mebendazole and praziquantel on glucosephosphate isomerase and glyceraldehydephosphate dehydrogenase in Echinococcus granulosus cyst wall harbored in mice. (1/136)
AIM: To study effects of antihydatid drugs on glucosephosphate isomerase (GPI) and glyceraldehydephosphate dehydrogenase (GAPDH) in Echinococcus granulosus cyst wall. METHODS: Mice infected with the parasite for 8-10 months were treated i.g. with mebendazole (Meb) or praziquantel (Pra). The activities of GPI and GAPDH in the cysts were measured by the formation of NADH or NADPH. RESULTS: GPI activity in the cyst wall was 197 +/- 103 U, while that of GAPDH was 25 +/- 13 U. When infected mice were treated i.g. with Meb 25-50 mg.kg-1.d-1 for 7-14 d, no apparent effect on the GAPDH activity in the cyst was found. In mice treated i.g. with praziquantel (Pra) 500 mg.kg-1.d-1 for 14 d, the GAPDH activity in the cyst wall was inhibited by 26.5%. As to GPI activity only the group treated i.g. with Meb 25 mg.kg-1.d-1 for 14 d showed 33.2% inhibition of the enzyme in the collapsed cyst wall. CONCLUSION: GPI and GAPDH are not the major targets attacked by the antihydatid drug. (+info)A controlled evaluation of two school-based anthelminthic chemotherapy regimens on intensity of intestinal helminth infections. (2/136)
BACKGROUND: School-based deworming programmes have been promoted as a cost-effective strategy for control of nematode infection in developing countries. While numerous efficacy studies have been conducted, there is little information on actual programme effectiveness in areas of intense transmission. METHODS: A randomized trial of a school-based deworming programme was conducted in 12 primary schools on Pemba Island, Zanzibar. Four schools each were randomized to control, twice a year deworming with single dose mebendazole or three times a year deworming. Baseline and 12-month follow-up data on helminth infection using the Kato-Katz technique, demographic information and nutritional status were collected on 3028 children from March 1994 to May 1995. RESULTS: Intensity of infection measured as eggs per gram of faeces (epg) declined significantly for Ascaris lumbricoides, Trichuris trichiura and hookworm infections in both treatment groups. A. lumbricoides infection intensity declined 63.1% and 96.7% in the twice and three times per year treatment groups compared to the controls. T. trichiura infection intensity declined 40.4% and 75.9% respectively and hookworm intensity declined 35.3% and 57.2% respectively compared to control schools. CONCLUSIONS: These results suggest that school-based programmes can be a cost-effective approach for controlling the intensity of intestinal helminth infection even in environments where transmission is high. (+info)Long-term evaluation of patients with hydatidosis treated with benzimidazole carbamates. (3/136)
Four hundred forty-eight patients with 929 Echinococcus granulosus hydatid cysts received 3- to 6-month continuous cycles of mebendazole or albendazole treatment and underwent prolonged follow-up by clinical visits and imaging studies (range, 1-14 years) to assess the long-term outcome of treatment. Degenerative changes and relapse were assessed by imaging techniques. At the end of therapy, 74.1% of the hydatid cysts showed degenerative changes. These were more frequent in albendazole-treated than in mebendazole-treated cysts (82.2% vs. 56.1%; P < .001). During long-term follow-up, 104 cysts (22%) had degenerative changes that progressed, whereas 163 cysts (approximately 25%) relapsed. The percentages of relapses in the two drug-treated groups were almost the same. Relapses occurred more frequently in type II cysts of the liver. Cysts recurred most often (78.5%; P < .001) within the first 2 years after treatment ended. Further chemotherapy cycles induced degenerative changes in >90% of relapsed cysts without inducing more frequent or more severe side effects than those observed during the initial cycles. (+info)Efficacy of various chemotherapeutic agents on the growth of Spironucleus vortens, an intestinal parasite of the freshwater angelfish. (4/136)
Seven chemotherapeutic agents (dimetridazole, metronidazole, pyrimethamine, albendazole, fenbendazole, mebendazole and magnesium sulfate) were examined for growth inhibition on the cultivation of Spironucleus vortens. Dimetridazole and metronidazole were effective in inhibiting the parasite's growth. At concentrations of 1 microgram ml-1 or higher, both dramatically decreased numbers of parasites. At 24 h exposure, 33% of parasites were inhibited when exposed to dimetridazole or metronidazole at concentrations of 2 and 4 micrograms ml-1, respectively. Dimetridazole at 4 micrograms ml-1 or higher concentrations decreased the number of organisms to 50% or less after 48 h exposure. During the same period of time, the numbers of parasites decreased to 50% or less when exposed to metronidazole at 6 micrograms ml-1 or higher. Pyrimethamine at concentrations of 1 to 10 micrograms ml-1 was not effective in inhibiting the parasite's growth. Albendazole and fenbendazole at concentrations of 0.1 and 0.5 microgram ml-1 were similar in inhibiting the growth of the organism. Both compounds suppressed parasite growth at concentrations of 1.0 microgram ml-1 or higher after 24 h exposure. Mebendazole inhibited the parasite's growth at concentrations of 0.5 microgram ml-1 or higher. At 72 h exposure, 45 to 50% of the parasites were inhibited when exposed to mebendazole at concentrations higher than 0.5 microgram ml-1. Magnesium sulfate at concentrations of 70 mg ml-1 or higher also suppressed the growth of parasites after 24 h exposure. These results indicate that dimetridazole, metronidazole and mebendazole are the most effective chemotherapeutic agents in vitro at inhibiting the growth of S. vortens. (+info)A case of presumed ocular toxocariasis in a 28-year old woman. (5/136)
This is a case of presumed ocular toxocariasis in a 28-year old woman complaining of a sudden onset of nasal side field defect of the right eye. The patient had been suffering from uveitis for ten months. Fundoscopic examination of the right eye showed a rhegmatogenous retinal detachment. Furthermore, a retinochoroidal granulomatous lesion was observed nearby the tear site. Scleral buckling, cryotherapy, and gas injection(SF6, pure gas, 0.7 cc) were conducted. Mebendazole was prescribed for one month at 25 mg/kg per body weight daily. Even though the interventions resulted in the recovery of the field defect, anti-Toxocara IgG and IgE titer levels did not decrease when checked three months after the treatment ended. This is the first confirmed serological ocular toxocariasis case in Korea. Uveitis may be a clinical presentation prior to retinal detachment of a person with toxocariasis. (+info)Pharmacokinetics of UMF-078, a candidate antifilarial drug, in infected dogs. (6/136)
The pharmacokinetics of the filaricidal benzimidazole compounds UMF-078 and UMF-289 were evaluated in beagle dogs experimentally infected with Brugia pahangi. Twenty-four infected microfilaremic beagles were selected and randomly allocated into 4 treatment groups of 6 dogs each: oral (PO) UMF-078, PO UMF-289 (the HCl salt form of UMF-078), intramuscular (IM) UMF-078, and untreated controls. Equivalent doses of 50 mg/kg of the free base were given twice a day for 3 days to the 3 groups of treated dogs. Oral absorption is rapid compared with IM dosing; the absorption half-life (K01-HL) for the IM treatment is approximately 14 hr compared with 1 and 2 hr for the PO regimen of salt and free base forms, respectively. The elimination half-lives (K10-HL) for the PO regimens are 13 and 15 hr for the salt and free base forms, respectively. Because of sustained absorption following IM dosing, the K10-HL is prolonged. In contrast to oral administration, IM dosing of UMF-078 provides sustained, relatively low plasma drug levels, with good tolerance and efficacy. (+info)Epidemiology and control of enterobiasis in a developmental center. (7/136)
OBJECTIVE: To determine if enterobiasis could be controlled in a developmental center. DESIGN: Population-based study. Annual screening of all residents by perianal swabs for enterobiasis and on admission or discharge. Treatment of infected residents and their contacts with mebendazole, 100 mg orally, with two doses given 14 days apart. MAIN OUTCOME MEASURES: The number of residents with enterobiasis and the cost of the program. RESULTS: The prevalence of enterobiasis fell rapidly and progressively, from 21% before mass medication to 1% after 3 years. CONCLUSION: Mass medication of residents with enterobiasis and their contacts was beneficial, harmless, and cost effective. (+info)Blinded, placebo-controlled trial of antiparasitic drugs for trichinosis myositis. (8/136)
There is no consensus on the benefits of treatment with any specific anthelminthic compound on muscle-stage trichinosis. A double-blind, placebo-controlled comparison was done of 3 antiparasitic drugs during an outbreak of trichinosis in Chiangrai Province, northern Thailand. Forty-six adults were randomized to receive 10 days of oral treatment with mebendazole (200 mg twice a day), thiabendazole (25 mg/kg twice a day), fluconazole (400 mg initially, then 200 mg daily), or placebo. All patients received treatment to eradicate adult intestinal worms. Trichinella spiralis infection was proved parasitologically in 19 (41%) of 46 patient and by serodiagnosis in all cases. Significantly more patients improved after treatment with mebendazole (12/12) and thiabendazole (7/7) than after treatment with placebo (6/12; P<.05) or fluconazole (6/12). Muscle tenderness resolved in more patients treated with thiabendazole and mebendazole than in those treated with placebo (P<.05). However, 30% of volunteers could not tolerate the side effects of thiabendazole. In summary, Trichinella myositis responds to thiabendazole and to mebendazole. (+info)Mebendazole is an antihelminthic medication used to treat various types of parasitic infections, including roundworms, tapeworms, and hookworms. It works by interfering with the metabolism of the parasites, leading to their death. Mebendazole is available in various forms, including tablets, capsules, and chewable tablets, and is typically taken orally. It is generally well-tolerated, but side effects may include nausea, abdominal pain, and diarrhea.
Antinematodal agents are medications that are used to treat parasitic worms, also known as nematodes. These agents work by either killing the worms or preventing their growth and reproduction. They are commonly used to treat infections caused by roundworms, hookworms, and whipworms, which are some of the most common types of parasitic worms that affect humans. Antinematodal agents can be administered orally or topically, depending on the specific worm infection and the severity of the infection. Some examples of antinematodal agents include albendazole, mebendazole, ivermectin, and pyrantel pamoate.
Albendazole is an antihelminthic medication used to treat a variety of parasitic infections, including roundworms, tapeworms, and hookworms. It works by interfering with the metabolism of the parasites, leading to their death. Albendazole is available in both oral and injectable forms and is commonly used in both humans and animals. It is generally well-tolerated, but like all medications, it can cause side effects, such as nausea, vomiting, and abdominal pain.
Anthelmintics are a class of drugs used to treat helminth (worm) infections in humans and animals. Helminths are parasitic worms that can cause a range of health problems, including abdominal pain, diarrhea, anemia, and malnutrition. Anthelmintics work by either killing the worms or preventing them from reproducing. There are several types of anthelmintics, including: 1. Benzimidazoles: These drugs are used to treat tapeworms, roundworms, and hookworms. They work by disrupting the worms' digestive system, causing them to starve and die. 2. Piperazines: These drugs are used to treat tapeworms and roundworms. They work by paralyzing the worms, making it easier to expel them from the body. 3. Ivermectin: This drug is used to treat a range of helminth infections, including roundworms, hookworms, and whipworms. It works by paralyzing the worms, making it easier to expel them from the body. 4. Mebendazole: This drug is used to treat roundworms, hookworms, and whipworms. It works by disrupting the worms' digestive system, causing them to starve and die. Anthelmintics are typically administered orally, although some may be administered topically or by injection. It is important to follow the instructions provided by a healthcare professional when taking anthelmintics, as they may have side effects and can interact with other medications.
Hookworm infections are a type of parasitic infection caused by the larvae of hookworms, which are microscopic roundworms that live in the intestines of humans and other animals. There are two main species of hookworms that can infect humans: Necator americanus and Ancylostoma duodenale. Hookworms are transmitted through skin contact with contaminated soil, typically in areas where the soil is contaminated with human feces. Once the larvae penetrate the skin, they migrate to the lungs and are then coughed up and swallowed, where they mature into adult worms in the small intestine. Hookworm infections can cause a range of symptoms, including abdominal pain, diarrhea, fatigue, anemia, and weight loss. In severe cases, hookworm infections can lead to malnutrition, developmental delays in children, and even death. Treatment for hookworm infections typically involves the use of antihelminthic drugs, which are medications that kill the worms. Prevention measures include avoiding contact with contaminated soil, wearing protective footwear, and practicing good hygiene, such as washing hands regularly.
Echinococcosis is a parasitic infection caused by the tapeworms of the genus Echinococcus. The infection occurs when the eggs of the tapeworm are ingested by a host, typically a mammal, and then develop into adult tapeworms in the host's digestive system. The adult tapeworms lay eggs that are excreted in the host's feces, which can then be ingested by another host, completing the life cycle of the parasite. Echinococcosis can affect humans and other animals, including dogs, sheep, and cattle. The infection can cause a range of symptoms, depending on the location and severity of the infection. In humans, the most common form of echinococcosis is cystic echinococcosis, which occurs when the tapeworm eggs develop into cysts in the liver, lungs, or other organs. Other forms of echinococcosis include alveolar echinococcosis, which affects the liver and lungs, and polycystic echinococcosis, which affects the brain and spinal cord. Echinococcosis is diagnosed through imaging tests, such as ultrasound or CT scans, and through the detection of the parasite's eggs in the host's feces or blood. Treatment for echinococcosis typically involves the use of anti-parasitic medications, surgery to remove cysts or other affected organs, or a combination of both. Prevention of echinococcosis involves avoiding contact with infected animals and their feces, and proper disposal of animal waste.
Trichuriasis is a parasitic infection caused by the whipworm Trichuris trichiura. It is also known as whipworm disease or threadworm infection. The parasite is transmitted through contaminated soil or food, and it infects the human colon and rectum. The symptoms of trichuriasis can vary depending on the severity of the infection. Common symptoms include abdominal pain, diarrhea, rectal bleeding, and anemia. In severe cases, the infection can lead to malnutrition, growth retardation, and other complications. The diagnosis of trichuriasis is typically made through a stool examination, which can detect the presence of the whipworm eggs. Treatment usually involves the administration of anthelmintic drugs, such as mebendazole or albendazole, which can kill the parasites. Prevention measures include improved sanitation and hygiene practices, such as handwashing and avoiding contact with contaminated soil or food.
Ascariasis is a type of parasitic infection caused by the roundworm Ascaris lumbricoides. It is one of the most common soil-transmitted helminth infections worldwide, particularly in developing countries. The adult worms live in the small intestine and lay eggs that are excreted in the feces. The eggs can then be ingested by humans or other animals, leading to reinfection. The symptoms of ascariasis can vary depending on the severity and duration of the infection. Common symptoms include abdominal pain, bloating, diarrhea, constipation, weight loss, and malnutrition. In severe cases, the worms can migrate to other parts of the body, such as the lungs, leading to respiratory symptoms such as coughing and wheezing. Treatment for ascariasis typically involves the use of anthelmintic drugs, such as albendazole or mebendazole, which are effective in killing the adult worms and their eggs. Preventive measures include improved sanitation and hygiene practices, such as handwashing and proper disposal of human waste.
Echinococcosis, hepatic, also known as hydatid disease, is a parasitic infection caused by the tapeworm Echinococcus granulosus. The infection occurs when the tapeworm's eggs are ingested and hatch in the small intestine, releasing larvae that can migrate to various parts of the body, including the liver. In the liver, the larvae form cysts that can grow and cause damage to the surrounding tissue. The cysts can be asymptomatic or cause symptoms such as abdominal pain, fever, and jaundice. In some cases, the cysts can rupture, leading to severe complications such as infection, bleeding, and organ failure. The diagnosis of hepatic echinococcosis is typically made through imaging studies such as ultrasound, CT scan, or MRI. Treatment options include surgery to remove the cysts, medical therapy with anti-parasitic drugs, or a combination of both. The prognosis for patients with hepatic echinococcosis depends on the size and location of the cysts, as well as the patient's overall health and response to treatment.
Pyrvinium compounds are a class of antiparasitic drugs that are used to treat various types of parasitic infections, including intestinal worms such as roundworms, hookworms, and whipworms. These compounds work by interfering with the ability of the parasites to absorb nutrients from the host's intestine, leading to their death and elimination from the body. Pyrvinium compounds are available in various forms, including tablets, capsules, and oral solutions. They are typically administered orally, and the dosage and duration of treatment depend on the type and severity of the infection. While pyrvinium compounds are generally safe and effective, they can cause side effects such as abdominal pain, diarrhea, nausea, and vomiting. In rare cases, they may also cause more serious side effects such as allergic reactions, liver damage, and neurotoxicity. Therefore, it is important to use these drugs under the guidance of a healthcare professional and to follow the recommended dosage and duration of treatment.
Ascaris lumbricoides is a type of roundworm that is commonly found in the human intestine. It is also known as the large intestine worm or the threadworm. The adult worms can grow up to 10-15 inches long and can live in the human intestine for several months. The eggs of the worm are passed in the feces and can be transmitted to other people through contaminated soil or food. Infection with Ascaris lumbricoides is known as ascariasis and can cause symptoms such as abdominal pain, diarrhea, and malnutrition. It is a common parasitic infection in many parts of the world, particularly in developing countries. Treatment for ascariasis typically involves the use of anthelmintic drugs to kill the worms.
Nematode infections, also known as helminth infections, are caused by parasitic roundworms called nematodes. These worms can infect various parts of the body, including the skin, lungs, intestines, and brain. The most common nematode infections include: 1. Ascariasis: caused by the roundworm Ascaris lumbricoides, which infects the small intestine. 2. Trichinosis: caused by the roundworm Trichinella spiralis, which infects the muscles. 3. Hookworm infection: caused by the roundworms Necator americanus and Ancylostoma duodenale, which infect the small intestine. 4. Strongyloidiasis: caused by the roundworm Strongyloides stercoralis, which infects the skin and lungs. 5. Filariasis: caused by the roundworms Wuchereria bancrofti, Brugia malayi, and Brugia timori, which infect the lymphatic system. Nematode infections can cause a range of symptoms, depending on the location and severity of the infection. Symptoms may include abdominal pain, diarrhea, nausea, vomiting, coughing, fever, and skin rash. In severe cases, nematode infections can lead to complications such as anemia, malnutrition, and organ damage. Treatment typically involves the use of antiparasitic medications to kill the worms or prevent their reproduction.
Enterobiasis, also known as pinworm infection, is a common parasitic infection that affects the digestive tract. It is caused by a small, thin, white worm called Enterobius vermicularis, which is commonly found in the colon and rectum of humans. The symptoms of enterobiasis include itching around the anus, especially at night, abdominal pain, nausea, and fatigue. The itching is caused by the female worm laying eggs on the skin around the anus, which can then be transferred to other parts of the body or to other people through contaminated clothing or bedding. Enterobiasis is most commonly spread through contaminated food or water, or by close personal contact with an infected person. It is particularly common in children, but can also affect adults. Treatment for enterobiasis typically involves the use of anti-parasitic medications, such as mebendazole or albendazole, which can kill the worms and their eggs. Prevention measures include good hygiene practices, such as washing hands regularly and avoiding contact with contaminated surfaces or objects, as well as proper sanitation and disposal of feces.
Benzimidazoles are a class of organic compounds that contain a six-membered ring with two nitrogen atoms and two carbon atoms. They are widely used in the medical field as drugs and as active ingredients in pesticides. In the medical field, benzimidazoles are used to treat a variety of conditions, including: 1. Helminth infections: Benzimidazoles are effective against a range of parasitic worms, including roundworms, tapeworms, and flukes. They work by interfering with the worms' ability to absorb glucose, which leads to their death. 2. Gastric ulcers: Benzimidazoles are used to treat stomach ulcers caused by the bacteria Helicobacter pylori. They work by inhibiting the production of enzymes that break down the stomach lining, allowing the ulcers to heal. 3. Migraines: Benzimidazoles are sometimes used to prevent migraines by reducing inflammation in the brain. 4. Cancers: Some benzimidazoles are being studied as potential treatments for certain types of cancer, including colon cancer and ovarian cancer. Overall, benzimidazoles are a versatile class of compounds with a wide range of potential medical applications.
Helminthiasis is a medical condition caused by the presence of parasitic worms (helminths) in the body. These worms can infect various organs and tissues, including the digestive system, lungs, liver, and brain. There are many different types of helminths that can cause helminthiasis, including roundworms, tapeworms, and flukes. The symptoms of helminthiasis can vary depending on the type of worm and the location of the infection. Common symptoms may include abdominal pain, diarrhea, nausea, vomiting, fatigue, and weight loss. Helminthiasis can be diagnosed through a variety of methods, including stool analysis, blood tests, and imaging studies. Treatment typically involves the use of antihelminthic drugs to kill or remove the worms from the body. In some cases, surgery may be necessary to remove large or deeply embedded worms. Prevention of helminthiasis involves good hygiene practices, such as washing hands regularly and avoiding contact with contaminated soil or water.
Angiostrongylus cantonensis is a parasitic nematode (roundworm) that can cause a serious infection in humans called angiostrongyliasis or rat lungworm disease. The parasite is commonly found in rats, snails, and slugs, and is transmitted to humans through the consumption of raw or undercooked infected food or water. The infection can cause a range of symptoms, including nausea, vomiting, abdominal pain, diarrhea, headache, and neck stiffness. In severe cases, the infection can lead to meningitis, which can be life-threatening if left untreated. Angiostrongylus cantonensis is found in many parts of the world, including Asia, the Pacific, and the Caribbean. Prevention of infection involves avoiding the consumption of raw or undercooked snails, slugs, or other foods that may be contaminated with the parasite, as well as avoiding contact with rats and other potential hosts.
Intestinal diseases caused by parasites are a group of conditions that affect the digestive system and are caused by the presence of parasites in the intestines. These parasites can be protozoa, helminths, or other microorganisms that live in the digestive tract and cause damage to the lining of the intestine, leading to symptoms such as abdominal pain, diarrhea, nausea, vomiting, and weight loss. Some common examples of parasitic intestinal diseases include: 1. Ascariasis: caused by the roundworm Ascaris lumbricoides, which can cause abdominal pain, diarrhea, and coughing up worms. 2. Giardiasis: caused by the protozoan Giardia lamblia, which can cause diarrhea, abdominal cramps, and bloating. 3. Hookworm infection: caused by the hookworms Necator americanus and Ancylostoma duodenale, which can cause anemia, abdominal pain, and weight loss. 4. Trichomoniasis: caused by the protozoan Trichomonas vaginalis, which can cause diarrhea, abdominal pain, and nausea. 5. Schistosomiasis: caused by parasitic flatworms called schistosomes, which can cause abdominal pain, diarrhea, and blood in the stool. Treatment for parasitic intestinal diseases typically involves the use of antiparasitic medications, although in some cases, surgery may be necessary. Prevention measures include practicing good hygiene, avoiding contaminated food and water, and using insect repellent to prevent mosquito bites.
Fenbendazole is an anthelmintic medication used to treat a variety of parasitic infections in animals, including sheep, goats, horses, and dogs. It works by paralyzing and killing the parasites in the digestive tract, allowing them to be eliminated from the body. Fenbendazole is available in various forms, including tablets, liquids, and pastes, and is typically administered orally. It is generally considered safe and effective for use in animals, but as with any medication, it is important to follow the recommended dosage and administration instructions provided by a veterinarian.
Echinococcosis, Pulmonary refers to a type of parasitic infection caused by the larval stage of the Echinococcus granulosus tapeworm. The larvae can migrate to the lungs and cause a variety of symptoms, including cough, chest pain, shortness of breath, and fever. In some cases, the infection can be asymptomatic and discovered incidentally on a chest X-ray or CT scan. Treatment typically involves the use of anti-parasitic medications, although surgery may be necessary in some cases.，，、、。
Praziquantel is an antiparasitic medication used to treat a variety of parasitic infections, including schistosomiasis (bilharzia), tapeworm infections, and liver fluke infections. It works by interfering with the metabolism of the parasites, leading to their death. Praziquantel is available in oral tablet form and is typically given as a single dose. It is considered safe and effective for most people, although it may cause side effects such as nausea, vomiting, and abdominal pain.
Pyrantel pamoate is an antihelminthic medication used to treat various types of parasitic infections, including roundworms, hookworms, and whipworms. It works by paralyzing the parasites, allowing the body's immune system to remove them. Pyrantel pamoate is available in oral tablet and suspension forms and is typically given as a single dose. It is generally well-tolerated, but side effects may include nausea, vomiting, abdominal pain, and diarrhea. Pyrantel pamoate is not effective against tapeworms or flukes.
Levamisole is an anthelmintic medication that is used to treat various types of parasitic infections, including roundworms, hookworms, and whipworms. It works by paralyzing the muscles of the parasites, allowing the body's immune system to remove them. In addition to its use as an anthelmintic, levamisole has also been used in the treatment of certain types of cancer, such as colorectal cancer. It is thought to work by stimulating the immune system to attack cancer cells. However, levamisole has also been associated with serious side effects, including fever, nausea, vomiting, abdominal pain, and skin rash. In some cases, it can cause more serious side effects, such as blood disorders, liver damage, and even death. As a result, the use of levamisole for cancer treatment has been largely discontinued in many countries, and it is now primarily used as an anthelmintic.
Anticestodal agents are medications that are used to treat infections caused by cestodes, which are a type of parasitic worm that includes tapeworms. These medications work by killing the cestodes or preventing them from reproducing, thereby eliminating the infection. Examples of anticestodal agents include praziquantel, albendazole, and mebendazole. These medications are typically taken orally and are effective in treating a variety of cestode infections, including those caused by tapeworms, liver flukes, and lung flukes. It is important to note that these medications should only be used under the guidance of a healthcare professional, as they can have side effects and may interact with other medications.
Pyrantel is an antiparasitic medication used to treat various types of parasitic infections, including roundworms, hookworms, and whipworms. It works by paralyzing the parasites, allowing the body's immune system to remove them. Pyrantel is available in various forms, including tablets, capsules, and oral suspensions, and is typically given orally. It is generally well-tolerated, but side effects may include nausea, vomiting, abdominal pain, and diarrhea. Pyrantel is not effective against tapeworms or flukes.
Hymenolepiasis is a type of parasitic infection caused by the roundworm Hymenolepis nana. It is also known as "pinworm" or "threadworm." The infection is common in children and is transmitted through contaminated food or water, or by direct contact with an infected person or animal. The adult worms live in the small intestine and lay eggs that are passed in the feces. The eggs can then hatch in the environment and infect another person or animal. The symptoms of hymenolepiasis include abdominal pain, itching around the anus, difficulty sleeping, and fatigue. In severe cases, the infection can cause malnutrition and anemia. Treatment for hymenolepiasis typically involves the use of antihelminthic drugs, such as mebendazole or albendazole, which kill the worms and their eggs. Prevention measures include good hygiene practices, such as washing hands regularly and avoiding contact with contaminated surfaces, as well as proper food and water sanitation.
Ancylostomatoidea is a superfamily of roundworms that includes several species that are commonly known as hookworms. These hookworms are parasitic worms that infect the small intestine of humans and other animals, including dogs, cats, and livestock. The most common species of hookworm that infects humans is Necator americanus, while the most common species that infects dogs and cats is Ancylostoma caninum. Hookworms are transmitted to humans and animals through contact with contaminated soil, typically in areas where human or animal feces are present. Once the hookworms enter the body, they migrate to the small intestine, where they attach themselves to the intestinal wall and feed on the host's blood. This can lead to anemia, malnutrition, and other health problems, particularly in children and people with weakened immune systems. Treatment for hookworm infections typically involves the use of anthelmintic drugs, which are medications that kill or expel the worms from the body. Prevention measures include practicing good hygiene, such as washing hands and avoiding contact with contaminated soil, and treating infected animals to prevent them from shedding hookworm eggs into the environment.
Mebendazole
Tubulin
Trichinosis
Albendazole
Runaways (House)
Trichostrongylus
Trichinella
Ancylostoma braziliense
Echinococcus multilocularis
Spirometra
Moniliformis moniliformis
Ancylostoma duodenale
Mass deworming
Soil-transmitted helminthiasis
Ascariasis
Ancylostoma ceylanicum
Raillietina echinobothrida
Mansonella perstans
Deworming
Janssen Pharmaceuticals
Pinworm infection
Angiostrongylus cantonensis
Toxocariasis
Capillaria philippinensis
Hookworm infection
Hookworm
Angiostrongyliasis
Trichuris trichiura
Trichuriasis
Anthelmintic
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