An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers.
An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI=weight (kg)/height squared (m2). BMI correlates with body fat (ADIPOSE TISSUE). Their relationship varies with age and gender. For adults, BMI falls into these categories: below 18.5 (underweight); 18.5-24.9 (normal); 25.0-29.9 (overweight); 30.0 and above (obese). (National Center for Health Statistics, Centers for Disease Control and Prevention)
A mass spectrometry technique used for analysis of nonvolatile compounds such as proteins and macromolecules. The technique involves preparing electrically charged droplets from analyte molecules dissolved in solvent. The electrically charged droplets enter a vacuum chamber where the solvent is evaporated. Evaporation of solvent reduces the droplet size, thereby increasing the coulombic repulsion within the droplet. As the charged droplets get smaller, the excess charge within them causes them to disintegrate and release analyte molecules. The volatilized analyte molecules are then analyzed by mass spectrometry.
A mass spectrometry technique using two (MS/MS) or more mass analyzers. With two in tandem, the precursor ions are mass-selected by a first mass analyzer, and focused into a collision region where they are then fragmented into product ions which are then characterized by a second mass analyzer. A variety of techniques are used to separate the compounds, ionize them, and introduce them to the first mass analyzer. For example, for in GC-MS/MS, GAS CHROMATOGRAPHY-MASS SPECTROMETRY is involved in separating relatively small compounds by GAS CHROMATOGRAPHY prior to injecting them into an ionization chamber for the mass selection.
A mass spectrometric technique that is used for the analysis of large biomolecules. Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. The matrix absorbs the laser energy, thus inducing a soft disintegration of the sample-matrix mixture into free (gas phase) matrix and analyte molecules and molecular ions. In general, only molecular ions of the analyte molecules are produced, and almost no fragmentation occurs. This makes the method well suited for molecular weight determinations and mixture analysis.
Chromatographic techniques in which the mobile phase is a liquid.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.
A mass-spectrometric technique that is used for microscopic chemical analysis. A beam of primary ions with an energy of 5-20 kiloelectronvolts (keV) bombards a small spot on the surface of the sample under ultra-high vacuum conditions. Positive and negative secondary ions sputtered from the surface are analyzed in a mass spectrometer in regards to their mass-to-charge ratio. Digital imaging can be generated from the secondary ion beams and their intensity can be measured. Ionic images can be correlated with images from light or other microscopy providing useful tools in the study of molecular and drug actions.
The relative amounts of various components in the body, such as percentage of body fat.
A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
The systematic study of the complete complement of proteins (PROTEOME) of organisms.
Organized periodic procedures performed on large groups of people for the purpose of detecting disease.
A microanalytical technique combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determinations of compounds.
A mass spectrometric technique that is used for the analysis of a wide range of biomolecules, such as glycoalkaloids, glycoproteins, polysaccharides, and peptides. Positive and negative fast atom bombardment spectra are recorded on a mass spectrometer fitted with an atom gun with xenon as the customary beam. The mass spectra obtained contain molecular weight recognition as well as sequence information.
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
The sum of the weight of all the atoms in a molecule.
The protein complement of an organism coded for by its genome.
A noninvasive method for assessing BODY COMPOSITION. It is based on the differential absorption of X-RAYS (or GAMMA RAYS) by different tissues such as bone, fat and other soft tissues. The source of (X-ray or gamma-ray) photon beam is generated either from radioisotopes such as GADOLINIUM 153, IODINE 125, or Americanium 241 which emit GAMMA RAYS in the appropriate range; or from an X-ray tube which produces X-RAYS in the desired range. It is primarily used for quantitating BONE MINERAL CONTENT, especially for the diagnosis of OSTEOPOROSIS, and also in measuring BONE MINERALIZATION.
Instruments or technological means of communication that reach large numbers of people with a common message: press, radio, television, etc.
Specialized connective tissue composed of fat cells (ADIPOCYTES). It is the site of stored FATS, usually in the form of TRIGLYCERIDES. In mammals, there are two types of adipose tissue, the WHITE FAT and the BROWN FAT. Their relative distributions vary in different species with most adipose tissue being white.
Electrophoresis in which a polyacrylamide gel is used as the diffusion medium.
Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are linear polypeptides that are normally synthesized on RIBOSOMES.
Events that overwhelm the resources of local HOSPITALS and health care providers. They are likely to impose a sustained demand for HEALTH SERVICES rather than the short, intense peak customary with smaller scale disasters.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
The measurement of an organ in volume, mass, or heaviness.
Elements of limited time intervals, contributing to particular results or situations.
The amount of mineral per square centimeter of BONE. This is the definition used in clinical practice. Actual bone density would be expressed in grams per milliliter. It is most frequently measured by X-RAY ABSORPTIOMETRY or TOMOGRAPHY, X RAY COMPUTED. Bone density is an important predictor for OSTEOPOROSIS.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
The technique that deals with the measurement of the size, weight, and proportions of the human or other primate body.
Analysis of PEPTIDES that are generated from the digestion or fragmentation of a protein or mixture of PROTEINS, by ELECTROPHORESIS; CHROMATOGRAPHY; or MASS SPECTROMETRY. The resulting peptide fingerprints are analyzed for a variety of purposes including the identification of the proteins in a sample, GENETIC POLYMORPHISMS, patterns of gene expression, and patterns diagnostic for diseases.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Electrophoresis in which a second perpendicular electrophoretic transport is performed on the separate components resulting from the first electrophoresis. This technique is usually performed on polyacrylamide gels.
Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.
Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.
A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.
Administration of a vaccine to large populations in order to elicit IMMUNITY.
Collective behavior of an aggregate of individuals giving the appearance of unity of attitude, feeling, and motivation.
Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
A status with BODY WEIGHT that is above certain standard of acceptable or desirable weight. In the scale of BODY MASS INDEX, overweight is defined as having a BMI of 25.0-29.9 kg/m2. Overweight may or may not be due to increases in body fat (ADIPOSE TISSUE), hence overweight does not equal "over fat".
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
The physical characteristics of the body, including the mode of performance of functions, the activity of metabolic processes, the manner and degree of reactions to stimuli, and power of resistance to the attack of pathogenic organisms.
Techniques for labeling a substance with a stable or radioactive isotope. It is not used for articles involving labeled substances unless the methods of labeling are substantively discussed. Tracers that may be labeled include chemical substances, cells, or microorganisms.
The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.
Partial proteins formed by partial hydrolysis of complete proteins or generated through PROTEIN ENGINEERING techniques.
The amount of fat or lipid deposit at a site or an organ in the body, an indicator of body fat status.
The rate dynamics in chemical or physical systems.
The chemical reactions involved in the production and utilization of various forms of energy in cells.
The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.
Statistical models in which the value of a parameter for a given value of a factor is assumed to be equal to a + bx, where a and b are constants. The models predict a linear regression.
The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.
The physical measurements of a body.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
An atom or group of atoms that have a positive or negative electric charge due to a gain (negative charge) or loss (positive charge) of one or more electrons. Atoms with a positive charge are known as CATIONS; those with a negative charge are ANIONS.
A state of insufficient flesh on the body usually defined as having a body weight less than skeletal and physical standards. Depending on age, sex, and genetic background, a BODY MASS INDEX of less than 18.5 is considered as underweight.
Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
The distance from the sole to the crown of the head with body standing on a flat surface and fully extended.
Proteins prepared by recombinant DNA technology.
Determination, by measurement or comparison with a standard, of the correct value of each scale reading on a meter or other measuring instrument; or determination of the settings of a control device that correspond to particular values of voltage, current, frequency or other output.
Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.
Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.
Chromatography on non-ionic gels without regard to the mechanism of solute discrimination.
Analysis based on the mathematical function first formulated by Jean-Baptiste-Joseph Fourier in 1807. The function, known as the Fourier transform, describes the sinusoidal pattern of any fluctuating pattern in the physical world in terms of its amplitude and its phase. It has broad applications in biomedicine, e.g., analysis of the x-ray crystallography data pivotal in identifying the double helical nature of DNA and in analysis of other molecules, including viruses, and the modified back-projection algorithm universally used in computerized tomography imaging, etc. (From Segen, The Dictionary of Modern Medicine, 1992)
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
A basis of value established for the measure of quantity, weight, extent or quality, e.g. weight standards, standard solutions, methods, techniques, and procedures used in diagnosis and therapy.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
A characteristic feature of enzyme activity in relation to the kind of substrate on which the enzyme or catalytic molecule reacts.
A research technique to measure solvent exposed regions of molecules that is used to provide insight about PROTEIN CONFORMATION.
Diseases of the uterine appendages (ADNEXA UTERI) including diseases involving the OVARY, the FALLOPIAN TUBES, and ligaments of the uterus (BROAD LIGAMENT; ROUND LIGAMENT).
Separation technique in which the stationary phase consists of ion exchange resins. The resins contain loosely held small ions that easily exchange places with other small ions of like charge present in solutions washed over the resins.
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure.
Decrease in existing BODY WEIGHT.
A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
Heat production, or its measurement, of an organism at the lowest level of cell chemistry in an inactive, awake, fasting state. It may be determined directly by means of a calorimeter or indirectly by calculating the heat production from an analysis of the end products of oxidation within the organism or from the amount of oxygen utilized.
Devices for accelerating charged particles in a spiral path by a constant-frequency alternating electric field. This electric field is synchronized with the movement of the particles in a constant magnetic field.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.
Glucose in blood.
A serine endopeptidase that is formed from TRYPSINOGEN in the pancreas. It is converted into its active form by ENTEROPEPTIDASE in the small intestine. It catalyzes hydrolysis of the carboxyl group of either arginine or lysine. EC
A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed)
Deuterium. The stable isotope of hydrogen. It has one neutron and one proton in the nucleus.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
A chromatographic technique that utilizes the ability of biological molecules to bind to certain ligands specifically and reversibly. It is used in protein biochemistry. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Any of various enzymatically catalyzed post-translational modifications of PEPTIDES or PROTEINS in the cell of origin. These modifications include carboxylation; HYDROXYLATION; ACETYLATION; PHOSPHORYLATION; METHYLATION; GLYCOSYLATION; ubiquitination; oxidation; proteolysis; and crosslinking and result in changes in molecular weight and electrophoretic motility.
Increase in BODY WEIGHT over existing weight.
The chemical or biochemical addition of carbohydrate or glycosyl groups to other chemicals, especially peptides or proteins. Glycosyl transferases are used in this biochemical reaction.
The sequence of carbohydrates within POLYSACCHARIDES; GLYCOPROTEINS; and GLYCOLIPIDS.
The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Progressive decline in muscle mass due to aging which results in decreased functional capacity of muscles.
Regular course of eating and drinking adopted by a person or animal.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
Proteins found in any species of bacterium.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins.
A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
The systematic identification and quantitation of all the metabolic products of a cell, tissue, organ, or organism under varying conditions. The METABOLOME of a cell or organism is a dynamic collection of metabolites which represent its net response to current conditions.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Total number of calories taken in daily whether ingested or by parenteral routes.
A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).
The measurement of subcutaneous fat located directly beneath the skin by grasping a fold of skin and subcutaneous fat between the thumb and forefinger and pulling it away from the underlying muscle tissue. The thickness of the double layer of skin and subcutaneous tissue is then read with a caliper. The five most frequently measured sites are the upper arm, below the scapula, above the hip bone, the abdomen, and the thigh. Its application is the determination of relative fatness, of changes in physical conditioning programs, and of the percentage of body fat in desirable body weight. (From McArdle, et al., Exercise Physiology, 2d ed, p496-8)
Studies in which variables relating to an individual or group of individuals are assessed over a period of time.
Appendages of the UTERUS which include the FALLOPIAN TUBES, the OVARY, and the supporting ligaments of the uterus (BROAD LIGAMENT; ROUND LIGAMENT).
A process that includes the determination of AMINO ACID SEQUENCE of a protein (or peptide, oligopeptide or peptide fragment) and the information analysis of the sequence.
The measurement around the body at the level of the ABDOMEN and just above the hip bone. The measurement is usually taken immediately after exhalation.
Chromatography on thin layers of adsorbents rather than in columns. The adsorbent can be alumina, silica gel, silicates, charcoals, or cellulose. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The lower right and left chambers of the heart. The right ventricle pumps venous BLOOD into the LUNGS and the left ventricle pumps oxygenated blood into the systemic arterial circulation.
The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.
Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
The waist circumference measurement divided by the hip circumference measurement. For both men and women, a waist-to-hip ratio (WHR) of 1.0 or higher is considered "at risk" for undesirable health consequences, such as heart disease and ailments associated with OVERWEIGHT. A healthy WHR is 0.90 or less for men, and 0.80 or less for women. (National Center for Chronic Disease Prevention and Health Promotion, 2004)
Concentration or quantity that is derived from the smallest measure that can be detected with reasonable certainty for a given analytical procedure.
State of the body in relation to the consumption and utilization of nutrients.
The cluster of cells inside a blastocyst. These cells give rise to the embryonic disc and eventual embryo proper. They are pluripotent EMBRYONIC STEM CELLS capable of yielding many but not all cell types in a developing organism.
Those characteristics that distinguish one SEX from the other. The primary sex characteristics are the OVARIES and TESTES and their related hormones. Secondary sex characteristics are those which are masculine or feminine but not directly related to reproduction.
Measurements of the height, weight, length, area, etc., of the human and animal body or its parts.
Atomic species differing in mass number but having the same atomic number. (Grant & Hackh's Chemical Dictionary, 5th ed)
The resistance to the flow of either alternating or direct electrical current.
Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)
An extraction method that separates analytes using a solid phase and a liquid phase. It is used for preparative sample cleanup before analysis by CHROMATOGRAPHY and other analytical methods.
The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.
Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.
The process of cleaving a chemical compound by the addition of a molecule of water.
The properties, processes, and behavior of biological systems under the action of mechanical forces.
The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.
Fractionation of a vaporized sample as a consequence of partition between a mobile gaseous phase and a stationary phase held in a column. Two types are gas-solid chromatography, where the fixed phase is a solid, and gas-liquid, in which the stationary phase is a nonvolatile liquid supported on an inert solid matrix.
Established cell cultures that have the potential to propagate indefinitely.
The vapor state of matter; nonelastic fluids in which the molecules are in free movement and their mean positions far apart. Gases tend to expand indefinitely, to diffuse and mix readily with other gases, to have definite relations of volume, temperature, and pressure, and to condense or liquefy at low temperatures or under sufficient pressure. (Grant & Hackh's Chemical Dictionary, 5th ed)
A type of pancreatic cell representing about 50-80% of the islet cells. Beta cells secrete INSULIN.
The amount of force generated by MUSCLE CONTRACTION. Muscle strength can be measured during isometric, isotonic, or isokinetic contraction, either manually or using a device such as a MUSCLE STRENGTH DYNAMOMETER.
Stable oxygen atoms that have the same atomic number as the element oxygen, but differ in atomic weight. O-17 and 18 are stable oxygen isotopes.
Techniques used to separate mixtures of substances based on differences in the relative affinities of the substances for mobile and stationary phases. A mobile phase (fluid or gas) passes through a column containing a stationary phase of porous solid or liquid coated on a solid support. Usage is both analytical for small amounts and preparative for bulk amounts.
Use of ultrasound for imaging the breast. The most frequent application is the diagnosis of neoplasms of the female breast.
Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
Deposits of ADIPOSE TISSUE throughout the body. The pattern of fat deposits in the body regions is an indicator of health status. Excess ABDOMINAL FAT increases health risks more than excess fat around the hips or thighs, therefore, WAIST-HIP RATIO is often used to determine health risks.
Carbohydrates consisting of between two (DISACCHARIDES) and ten MONOSACCHARIDES connected by either an alpha- or beta-glycosidic link. They are found throughout nature in both the free and bound form.
Mixtures of many components in inexact proportions, usually natural, such as PLANT EXTRACTS; VENOMS; and MANURE. These are distinguished from DRUG COMBINATIONS which have only a few components in definite proportions.
The consumption of edible substances.
The phenomenon whereby certain chemical compounds have structures that are different although the compounds possess the same elemental composition. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).
Tumors in any part of the heart. They include primary cardiac tumors and metastatic tumors to the heart. Their interference with normal cardiac functions can cause a wide variety of symptoms including HEART FAILURE; CARDIAC ARRHYTHMIAS; or EMBOLISM.
The parts of a macromolecule that directly participate in its specific combination with another molecule.
Fluids composed mainly of water found within the body.
Derangement in size and number of muscle fibers occurring with aging, reduction in blood supply, or following immobilization, prolonged weightlessness, malnutrition, and particularly in denervation.
Single-stranded complementary DNA synthesized from an RNA template by the action of RNA-dependent DNA polymerase. cDNA (i.e., complementary DNA, not circular DNA, not C-DNA) is used in a variety of molecular cloning experiments as well as serving as a specific hybridization probe.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
A growth differentiation factor that is a potent inhibitor of SKELETAL MUSCLE growth. It may play a role in the regulation of MYOGENESIS and in muscle maintenance during adulthood.
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.
The condition of weighing two, three, or more times the ideal weight, so called because it is associated with many serious and life-threatening disorders. In the BODY MASS INDEX, morbid obesity is defined as having a BMI greater than 40.0 kg/m2.
Inhaling and exhaling the smoke of burning TOBACCO.
Separation of a mixture in successive stages, each stage removing from the mixture some proportion of one of the substances, for example by differential solubility in water-solvent mixtures. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The physical activity of a human or an animal as a behavioral phenomenon.
A spectroscopic technique in which a range of wavelengths is presented simultaneously with an interferometer and the spectrum is mathematically derived from the pattern thus obtained.
Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other.
The dynamic collection of metabolites which represent a cell's or organism's net metabolic response to current conditions.
The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
A multistage process that includes the determination of a sequence (protein, carbohydrate, etc.), its fragmentation and analysis, and the interpretation of the resulting sequence information.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
The development and use of techniques and equipment to study or perform chemical reactions, with small quantities of materials, frequently less than a milligram or a milliliter.
Sequential operating programs and data which instruct the functioning of a digital computer.
Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.
Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
Any fluid-filled closed cavity or sac that is lined by an EPITHELIUM. Cysts can be of normal, abnormal, non-neoplastic, or neoplastic tissues.
The pH in solutions of proteins and related compounds at which the dipolar ions are at a maximum.
The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)
A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
Typical way of life or manner of living characteristic of an individual or group. (From APA, Thesaurus of Psychological Index Terms, 8th ed)
Conjugated protein-carbohydrate compounds including mucins, mucoid, and amyloid glycoproteins.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Transport proteins that carry specific substances in the blood or across cell membranes.
A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
Proteins that are present in blood serum, including SERUM ALBUMIN; BLOOD COAGULATION FACTORS; and many other types of proteins.

Screening for cervical cancer: a review of women's attitudes, knowledge, and behaviour. (1/10392)

The United Kingdom (UK) cervical screening programme has been successful in securing participation of a high proportion of targeted women, and has seen a fall in mortality rates of those suffering from cervical cancer. There remains, however, a significant proportion of unscreened women and, of women in whom an abnormality is detected, many will not attend for colposcopy. The present work reviews the psychological consequences of receiving an abnormal cervical smear result and of secondary screening and treatment, and examines reasons for women's non-participation in the screening programme. Psychological theories of screening behavior are used to elucidate women's reactions and to suggest methods of increasing participation, of improving the quality of the service, and of reducing women's anxiety. A literature search identified studies that examine factors influencing women's participation in the screening programme, their psychological reaction to the receipt of an abnormal cervical smear result, and experiences of colposcopy. Reasons for non-participation include administrative failures, unavailability of a female screener, inconvenient clinic times, lack of awareness of the test's indications and benefits, considering oneself not to be at risk of developing cervical cancer, and fear of embarrassment, pain, or the detection of cancer. The receipt of an abnormal result and referral for colposcopy cause high levels of distress owing to limited understanding of the meaning of the smear test; many women believe the test aims to detect existing cervical cancer. The quality of the cervical screening service can be enhanced by the provision of additional information, by improved quality of communication, and by consideration of women's health beliefs. This may result in increased participation in, and satisfaction with, the service.  (+info)

The PRIME study: classical risk factors do not explain the severalfold differences in risk of coronary heart disease between France and Northern Ireland. Prospective Epidemiological Study of Myocardial Infarction. (2/10392)

We are studying the contribution of risk and genetic factors, and their interaction, to the development of ischaemic heart disease (IHD) and other cardiovascular endpoints. The study is prospective, based in three centres in the south, east and north of France and in Northern Ireland. A total of 10,592 men aged 50-59 years were recruited from 1991 to 1993, and examined for evidence of IHD at baseline. Subjects are followed annually by questionnaire. Clinical information is validated from hospital and GP records. Demographic characteristics were similar in all four centres. Body mass index was highest in Strasbourg (mean 27.4 kg/m2 vs. 26.3 kg/m2 in Toulouse and Belfast), but total cholesterol, triglyceride and fibrinogen were highest in Belfast. In Belfast, 6.1% reported having had a coronary angiogram, compared to 3.0% in Toulouse. Conversely, 13.8% in Toulouse reported taking lipid-lowering drugs vs. 1.6% in Belfast. As predicted, a history of myocardial infarction (MI) was highest in Belfast (6.1%) and lowest in Toulouse (1.2%). Some 7.1% of Belfast men reported a medical diagnosis of angina vs. 1.5% in Toulouse. Subjects showing evidence of pre-existing IHD will be studied prospectively but treated in the analysis as an additional variable. These results provide a measure of reassurance that these cohorts are representative of the communities from which they are drawn and provide a reliable baseline for prospective evaluation and cross-sectional comparisons. The levels of the classical risk factors found in this study, particularly when examined in combination, as multiple logistic functions based on previous British studies, are very similar between centres and cannot explain the large differences in the incidence of IHD which exist. Additional risk factors may help explain, at least in part, the major differences in incidence of IHD between these study centres.  (+info)

Coeliac disease detected by screening is not silent--simply unrecognized. (3/10392)

Coeliac disease (CD) is associated with a wide spectrum of clinical presentation and may be overlooked as a diagnosis. There is some evidence that untreated CD is associated with a doubling of mortality, largely due to an increase in the incidence of malignancy and small intestinal lymphoma, which is decreased by a strict gluten-free diet. We studied the clinical features of screening-detected coeliacs compared to age- and sex-matched controls as a 3-year follow-up to a population screening survey, and followed-up subjects who had had CD-associated serology 11 years previously to determine whether they have CD or an increased mortality rate compared to the general population. Samples of the general population (MONICA 1991 and 1983) were screened for CD-associated serology and followed-up after 3 and 11 years, respectively, and assessed by a clinical questionnaire, screening blood tests and jejunal biopsy. Mortality rates for 'all deaths' and 'cancer deaths' were compared in subjects with positive serology in 1983 with reference to the general population. Thirteen coeliacs were diagnosed by villous atrophy following screening, compared to two patients with clinically detected CD, giving a prevalence of 1:122. Clinical features or laboratory parameters were not indicative of CD compared to controls. Subjects with positive serology followed up after 11 years did not have an excess mortality for either cancer deaths or all causes of death. Screening-detected CD is rarely silent and may be associated with significant symptoms and morbidity. In this limited study with small numbers, there does not appear to be an increased mortality from screening-detected CD, although the follow-up may be too short to detect any difference.  (+info)

Faecal occult blood screening and reduction of colorectal cancer mortality: a case-control study. (4/10392)

To estimate the efficacy of screening on colorectal cancer mortality, a population-based case-control study was conducted in well-defined areas of Burgundy (France). Screening by faecal occult blood test prior to diagnosis in cases born between 1914 and 1943 and who died of colorectal cancer diagnosed in 1988-94 was compared with screening in controls matched with the case for age, sex and place of residence. Cases were less likely to have been screened than controls, with an odds ratio (OR) of 0.67 [95% confidence interval (CI) 0.48-0.94]. The negative overall association did not differ by gender or by anatomical location. The odds ratio of death from colorectal cancer was 0.64 (95% CI 0.46-0.91) for those screened within 3 years of case diagnosis compared with those not screened. It was 1.14 (95% CI 0.50-2.63) for those screened more than 3 years before case diagnosis. There was a negative association between the risk of death from colorectal cancer and the number of participations in the screening campaigns. The inverse association between screening for faecal occult blood and fatal colorectal cancer suggests that screening can reduce colorectal cancer mortality. This report further supports recommendations for population-based mass screening with faecal occult blood test.  (+info)

The identification of agreed criteria for referral following the dental inspection of children in the school setting. (5/10392)

AIM: To clarify the function of the school based dental inspection. OBJECTIVE: For representatives of the Community Dental Service, General Dental Service and Hospital Dental Service to identify an agreed set of criteria for the referral of children following school dental inspection. DESIGN: Qualitative research methodology used to establish a consensus for the inclusion of referral criteria following dental screening. SETTING: Ellesmere Port, Cheshire, England. MATERIALS: A Delphi technique was used to establish a consensus amongst the study participants on the inclusion of nine possible criteria for referral following dental screening. All participants scored each criterion in the range 1-9, with a score of 1 indicating that referral of individuals with the condition should definitely not take place, and a score of 9 indicating referral should definitely take place. Referral criteria were accepted only if they achieved a group median score of 7 or more, with an interquartile range of three scale points, with the lower value being no less than 7. RESULTS: Four of the nine possible criteria met the agreed group standard for inclusion: 'Sepsis', 'Caries in the secondary dentition', 'Overjet > 10 mm', and 'Registered & caries in the permanent dentition'. CONCLUSION: It is possible to agree clear criteria for the referral of children following the school dental inspection.  (+info)

Special medical examination program reform proposal in Korea. (6/10392)

We are at a time when reform in the special medical examination program in keeping with the changing times is desperately needed because the common perception of workers, employers, and medical examination facilities is "special medical examination is merely ritualistic and unproductive." Therefore, we have tried to set forth the basic structure for reforming the special medical examination program by taking a close look at the management status of the current program and analyzing its problems. The specifics of the special medical examination program reform proposal consist of three parts such as the types, health evaluation based on occupational medicine, and the interval, subject selection, items and procedure. Pre-placement medical examination and non-periodic medical examinations-as-necessary are introduced newly. Health evaluation based on occupational medicine consists of classification of health status, evaluation of work suitability, and post-examination measure. Details regarding the medical examination interval, subject selection, items and procedure were changed.  (+info)

Screening Mammography Program of British Columbia: pattern of use and health care system costs. (7/10392)

BACKGROUND: The use of mammography for screening asymptomatic women has increased dramatically in the past decade. This report describes the changes that have occurred in the use of bilateral mammography in British Columbia since the provincial breast cancer screening program began in 1988. METHODS: Using province-wide databases from both the breast cancer screening program and the provincial health insurance plan in BC, the authors determined the number and costs of bilateral mammography services for women aged 40 years or older between Apr. 1, 1986, and Mar. 31, 1997. Unilateral mammography was excluded because it is used for investigating symptomatic disease and screening abnormalities, and for follow-up of women who have undergone mastectomy for cancer. RESULTS: As the provincial breast cancer screening program expanded from 1 site in 1988 to 23 in 1997, it provided an increasing proportion of the bilateral mammographic examinations carried out each year in BC. In fiscal year 1996/97, 65% of bilateral mammographic examinations were performed through the screening program. The cost per examination within the screening program dropped as volume increased. Thirty percent more bilateral mammography examinations were done in 1996/97 than in 1991/92, but health care system expenditures for these services increased by only 4% during the same period. In calendar year 1996, 21% of new breast cancers were diagnosed as a result of a screening program visit. INTERPRETATION: Substantial increases in health care expenditures have been avoided by shifting bilateral mammography services to the provincial screening program, which has a lower cost per screening visit.  (+info)

Pap screening clinics with native women in Skidegate, Haida Gwaii. Need for innovation. (8/10392)

PROBLEM ADDRESSED: First Nations women in British Columbia, especially elders, are underscreened for cancer of the cervix compared with the general population and are much more likely to die of the disease than other women. OBJECTIVE OF PROGRAM: To develop a pilot program, in consultation with community representatives, to address the Pap screening needs of First Nations women 40 years and older on a rural reserve. MAIN COMPONENTS OF PROGRAM: Identification of key links to the population; consultation with the community to design an outreach process; identification of underscreened women; implementation of community Pap screening clinics; evaluation of the pilot program. CONCLUSIONS: We developed a Pap screening outreach program that marked a departure from the usual screening approach in the community. First Nations community health representatives were key links for the process that involved family physicians and office staff at a local clinic on a rural reserve. Participation rate for the pilot program was 48%, resulting in an increase of 15% over the previously recorded screening rate for this population. More screening clinics of this type and evaluation for sustainability are proposed.  (+info)

The United States Preventive Services Task Force (USPSTF) has recently issued recommendations for the screening of colorectal cancer. These recommendations were published in the Archives of Internal Medicine.. Recommendations for the screening of colorectal cancer include screening initiation at the age of 50 years for all individuals, or younger for those at a high risk for developing the disease. ?Because colorectal cancer is a type of cancer that is highly curable in early stages, universal screening of individuals remains of utmost importance in order to improve overall outcomes for the disease.. The USPSTF is a panel of general care experts who provide recommendations for treatment and prevention of certain diseases. For the first time, the USPSTF has recommended changes to screening for colorectal cancer as well as additions to the historic recommendations.. ...
Mass-screening for lung cancer is rather a unique system in Japan. This study illustrates time from finding abnormality on mass-screening to final diagnosis of lung cancer. Among the 517 patients with lung cancer who were admitted to our hospital over a 10-year period up to December 2001, 83 (16.1%) were detected by mass-screening. We reviewed medical records of the 83 patients and determined the intervals from the mass-screening to the pathological diagnosis with clinical staging. Time from the mass-screening to the date of hospital visit was ...
This study reports the outcome of active surveillance in men with PSA screening-detected prostate cancer (PC), and PSA doubling time (PSADT) was evaluated as a predictor of selecting patients to active treatment or surveillance. On December 31, 1994, 10,000 men were randomized to biennial PSA testing. Through to December 2004, a total of 660 men were diagnosed with PC, of whom 270 managed with initial surveillance. Of these 270 patients, 104 (39%) received active treatment during follow-up, 70 radical prostatectomy, 24 radiation and 10 endocrine treatment. Those who received active treatment during follow-up (mean 63 months) were significantly younger (62.6 vs. 65.5 years, p | 0.0001) and had a shorter PSADT (3.7 vs. 12 years, p | 0.0001). PSA relapse was observed in 9 of 70 patients who received RRP during a mean follow-up of 37 months. Seven of these nine PSA relapses were in the patients with preoperative PSADT | 2 years. None of the 37 operated patients with a PSADT | 4 years had a PSA relapse. In a
Summarizing recommendations of an authoritative panel, this book serves as a guide to implementing preventive screening and counseling for optimum patient care while minimizing costly and unnecessary tests. Includes 169 interventions for 60 of the most important preventable disease entities and health issues. ...
The United States Preventive Services Task Force issued their final recommendation on the PSA prostate cancer-screening test Monday, recommending against routine PSA exams for men of any age.
The United States Preventive Services Task Force issued their final recommendation on the PSA prostate cancer-screening test Monday, recommending against routine PSA exams for men of any age.
Lung cancer is usually asymptomatic until it has reached an advanced stage, when the treatment outcome is poor. Five-year survival for all stages is 11-14% for Stage I it is 42-47%.1 Under optimal conditions, survival can be higher.10,12,13 Early detection of Stage I cases through screening might be expected to improve survival, but the small amount of available evidence does not show that screening reduces lung cancer mortality.. The efficacy of chest radiographic screening for lung cancer was first investigated in the 1960s. A controlled prospective study involving over 55,000 persons found that those receiving chest x-rays every 6 months had a larger proportion of resectable tumors, but mortality for lung cancer remained the same when compared with controls who received examinations only at the beginning and end of the trial.14 Similar findings were reported in the Philadelphia Pulmonary Neoplasm Research Project15 and, more recently, in a case-control study.16 In addition, the results of one ...
A RESOLUTION urging the United States Congress, the Department of Health and Human Services, and Centers for Medicare and Medicaid Services to ignore the recent guidelines for breast cancer screenings by the United States Preventive Services Task Force; and for other purposes.
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USPSTF 2016 recommendations on statin use for primary prevention of CVD Clinical Question:What are the benefits and harms of statin treatment for dyslipidemia in adults 21 years and older?Bottom Line:The United States Preventive Services Task Force (USPSTF) now recommends that adultswithout a history of cardiovascular disease (CVD) use a low- to moderate-dose statin for the…
Background Celiac disease (CD) is a chronic disorder in genetically predisposed individuals in which damage to the small intestine is caused by eating foods containing gluten. The prevalence has been shown to vary from around 1-3%, but most people with CD are undiagnosed. An option for finding those with unrecognized CD would include screening the general population, i.e., mass screening. However, screening identifies a pre-disease or disease condition in people who are presumed healthy and have not sought help. Therefore, the impacts of the screening process and being diagnosed through screening should be explored before such a public health intervention is considered. A population-based CD screening study involving 12-year-olds was undertaken in Sweden and provided an opportunity to explore these issues related to CD screening.. Aims To make inferences about the potential impacts mass screening for CD can have on participants by exploring experiences and outcomes for participants involved in ...
See related article, pp 1142-1147. It has been clear for decades that elevated blood pressure in adults is strongly associated with adverse cardiovascular disease outcomes,1 including myocardial infarction, cerebrovascular disease, and congestive heart failure. It has been harder to establish a direct association between elevated blood pressure in children and adolescents and cardiovascular disease in adulthood. This has, in part, led the United States Preventive Services Task Force to report an I statement,2 indicating that there is insufficient evidence for or against blood pressure screening in pediatric patients. Such direct evidence would be valuable to have in hand; however, because these relationships develop longitudinally, this evidence is difficult, if not impossible, to obtain. To evaluate the direct link between childhood risk factors such as hypertension and adult cardiovascular outcomes requires studies with a high level of follow-up that take place over many decades.. Despite this ...
TB in the United States, because it substantially reduces the risk that TB infection will progress to TB disease. The Centers for Disease Control and Prevention (CDC) and the United States Preventive Services Task Force (USPSTF) recommend testing populations that are at increased risk for TB infection. Once the diagnosis of LTBI has been made, health care providers must choose the most appropriate and effective treatment regimen, and make every effort to ensure those persons complete the entire course of treatment for LTBI ...
Shingles can also resume exelon 4.5 mg capsule some of the sponsors or the beach. The walls of the most common known cause of new cancer cases (rate: 17 cases per 100,000 population were age adjusted to the United States Preventive Services Task Force recommendation against testing the aerosols which would have wanted to share or watch videos on scientific topics and provide scientific knowledge. The answer to that person.. In some countries, AMA PRA credit may be isolated or not be permitted to return to the different ways viruses can spread viruses like Japanese encephalitis and yellow fever. Press Release Embargoed exelon 4.5 mg capsule Until: Tuesday, January 9, 2019, 13 additional ill people have already been achieved, whereas objectives for other influenza A virus infection. Screening and regulatory officials use population-based cancer survival; stomach cancer.. Pediatric Management Illness among pediatric patients with hemophilia and to help keep ...
Despite the controversy that erupted when its draft recommendations were released last year, the United States Preventive Services Task Force (USPSTF) did not change its grade
Applied DNA believes that the multi-S-gene-target design of its Assay Kit gives it a substantial advantage in the detection of certain variants.
LUMBERTON - Lumberton residents can maintain good health by getting tests, checkups and immunizations with the Affordable Care Act.. The Affordable Care Act covers many tests and screenings without meeting co-pays, co-insurance or deductibles when the services are completed by an in-network provider.. There are dozens of preventative services that may be covered for adults and children. Some of the services include:. - Blood pressure screenings.. - Breast, cervical and colorectal cancer screenings.. - Diabetes screenings.. - Screenings for sexually transmitted infections, including HIV.. - Vaccinations.. - Checkups for women.. - Vision and hearing checks for children.. - Abdominal aortic aneurysm screenings.. Services covered under the Affordable Care Act have earned either an A or B rating from the U.S. Preventative Services Task Force. This means the services are likely to provide health benefits.. Tests and preventative care recommendations depend on age, medical history and sex. ...
NEW YORK (AP) - A panel of health experts wants U.S. adults to start getting colon cancer screenings at age 45, five years younger than it previously recommended. While overall, colon cancer rates have been declining, the draft guidelines issued Tuesday by the U.S. Preventive Services Task Force reflect a growing concern about rising rates […]
Several organizations including the FDA, Centers for Disease Control and Prevention (CDC), and the United State Preventive Services Taskforce have suggested that direct access testing can be used effectively in a few screening scenarios (12). These tests include lipid panels, glucose, HIV testing, and Hemoglobin A1c. The CDC does emphasize that these tests are not to be used for diagnostic purposes and to be used in conjunction with a medical provider.. DAT has been increasingly used for the detection of STD pathogens. DATs developed utilizing non-invasive, easy-to-collect specimens have been successful in detection of HIV as well as other STD pathogens. HIV self-test kits have the potential to increase testing rates around the globe and thereby lead to reductions in HIV morbidity and mortality (13). Several studies assessed the feasibility and acceptability among women of self-collecting cervicovaginal samples at home, returning samples by mail for HPV testing, and receiving HPV results by ...
BACKGROUND: Because of the recent grade C draft recommendation by the US Preventive Services Task Force (USPSTF) for prostate cancer screening between the ages of 55 and 69 years, there is a need to determine whether this could be cost-effective in a US population setting. METHODS: This study used a microsimulation model of screening and active surveillance (AS), based on data from the European Randomized Study of Screening for Prostate Cancer and the Surveillance, Epidemiology, and End Results Program, for the natural history of prostate cancer and Johns Hopkins AS cohort data to inform the probabilities of referral to treatment during AS ...
This detection rate is comparable to that of specialized prenatal diagnosticians in the California Serum MS-AFP program who were specifically tasked with finding anomalies in screen positive patients ...
The U.S. Preventative Services Task Force (USPSTF) released draft recommendations for low-dose helical CT for lung cancer screening for a select group of high-risk patients based on results of the National Lung Screening Trial (NLST). The USPSTF recommends annual CT screening of smokers 55-79 years old who have at least a 30 pack-year smoking history and who are well enough to undergo definitive therapy for lung cancer. Former smokers who quit less than 15 years ago who also meet the other criteria should also be offered CT screening. A 30-day comment period is underway. ...
Health, By Amy Norton HealthDay Reporter ...TUESDAY Nov. 27 (HealthDay News) -- The contentious U.S. guidelines t...In 2009 the U.S. Preventive Services Task Force -- an independent med...Instead the task force said women in their 40s can discuss mammograp...Thats out of step with advice from other groups such as the American...,More,Cancers,May,Be,Missed,Under,Latest,Mammogram,Guidelines,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
A panel of health experts wants U.S. adults to start getting colon cancer screenings at age 45, five years younger than it previously recommended.
We performed a pilot RCT to learn how best to use HE4 in a staged multimodal screening protocol, to inform the design of future screening protocols. To assess safety, we chose trial size to yield primary outcome estimation (for both arms combined) of a 95% CI for surgical PPV; we had 80% power to rule out inclusion of PPV of 10% or lower. We observed fewer surgeries and malignancies than expected, and observed an overall surgical PPV of 33%, with 95% CI of 4%-78%. The trial was not large enough to test the difference in PPV between arms, and no statistically significant difference was seen. Both screening protocols were found to be feasible and acceptable to women and physicians; neither resulted in excessive imaging, surgical consults, or surgical procedures.. Positive screens were more frequent when HE4 was included in the primary screen. Consistent with retrospective analysis of Prostate, Lung, Colorectal, and Ovary Cancer Screening Trial (PLCO) data (21), these data suggest that HE4 may be ...
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Today, all newly diagnosed patients with HIV will need a variety of tests to accurately confirm diagnosis, evaluate the amount of virus in the blood and ...
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Interval cancers are tumors arising after a negative screening episode and before the next screening invitation. They can be classified into true interval cancers, false-negatives, minimal-sign cancers, and occult tumors based on mammographic findings in screening and diagnostic mammograms. This study aimed to describe tumor-related characteristics and the association of breast density and tumor phenotype within four interval cancer categories. We included 2,245 invasive tumors (1,297 screening-detected and 948 interval cancers) diagnosed from 2000 to 2009 among 645,764 women aged 45 to 69 who underwent biennial screening in Spain. Interval cancers were classified by a semi-informed retrospective review into true interval cancers (n = 455), false-negatives (n = 224), minimal-sign (n = 166), and occult tumors (n = 103). Breast density was evaluated using Boyds scale and was conflated into: |25%; 25 to 50%; 50 to 75%; |75%. Tumor-related information was obtained from cancer registries and clinical
Racial and ethnic minorities, low-income persons, and those who are uninsured or insured by Medicaid are more likely to have poor cancer outcomes. This may be due, in part, to lower use of screening tests. The Cancer Screening Office Systems program--a low-cost, non-computerized program--increased the use of screening tests in primary care practices serving these groups. The program focused on 3 cancer-screening tests: mammograms, Pap smears, and fecal occult blood tests (a test for digestive system problems including colon cancer). As part of the program, patients completed a checklist about when they last received cancer-screening tests. The medical office used a series of stickers on medical records to show whether cancer-screening tests were due, ordered, or completed. In addition, office staff members were assigned specific roles in carrying out the program. ...
The following is information about the U.S. Preventive Services Task Force (USPSTF) for use by the media.. The USPSTF is an independent panel of non-Federal experts that makes recommendations on clinical preventive services, such as screenings, counseling, and preventive medications, to primary care clinicians. USPSTF recommendations apply to people with no signs or symptoms of the disease, and are based on a rigorous, systematic review of peer-reviewed evidence.. USPSTF members are primary care providers (such as internists, pediatricians, family physicians, nurses, gynecologists/obstetricians, and health behavior specialists) who are experts in prevention and evidence-based medicine. Members are required to disclose any possible conflicts of interest for each topic under review.. To learn more about:. ...
TUESDAY, Aug. 18, 2020 (HealthDay News) -- Women smokers already have one bad habit. A new study finds another: Theyre less likely than others to go for cancer screenings.. Moreover, theyre more likely to have spreading cancer when diagnosed, according to findings. For the report, researchers collected data on more than 89,000 postmenopausal women who took part in a long-running U.S. study. More than half had never smoked; 41% were former smokers; and 6% were current smokers, although nearly half of these women quit smoking by the end of the study. Over an average of nine years of follow-up, more than 7,000 women developed breast cancer, 1,600 had colon cancer and 61 had cervical cancer. Compared with nonsmokers, former smokers were more likely to have regular cancer screenings, but current smokers were much less likely to do so. The report was published online Aug. 13 in the journal BMJ Open. Concern for personal health is the most common reason given for smoking cessation among former ...
Mammography is effective in the early detection of breast cancer, especially among women 50 years and older. Detection and treatment of breast cancer at an early stage of disease can improve survival and yield substantial savings in medical care costs. This manual is a source of basic information on mammography and the intervention strategies and tools that health plans may use to help increase the screening rates. The manual is designed to be user-friendly, practical and adaptable to the needs and capacity of different health plans and will assist health plans to: 1. assess existing barriers to mammography; 2. identify the characteristics of members, providers and health care delivery systems for use in tailoring intervention strategies to increase their effectiveness; 3. identify the population(s) and providers(s) to target for intervention as well as the missed and untapped opportunities to increase mammography rates; 4. select and implement appropriate intervention strategies including those ...
Theres a bit of controversy among doctors and researchers over whether annual physicals are actually necessary for healthy patients, but new research has identified one distinct benefit of routine visits with a primary care physician: increased colon cancer screenings.. Colon cancer is the third most common cancer among men and women in the United States. Current screening guidelines recommend that most individuals begin routine screening at the age of 50 and every 10 years thereafter. However, despite these recommendations, reports by the Centers for Disease Control and Prevention (CDC) indicate that only 65.1 percent of eligible individuals are current with colon cancer screenings ...
Ji Young Bang MBBS MPH, Azeem Majeed MD FRCGP FFPH Department of Primary Care & Public Health, Imperial College Faculty of Medicine, London, W6 8RP, UK July 5, 2012 Screening for Cervical Cancer: U.S. Preventive Services Task Force Recommendation Statement As in the USA, cervical cancer incidence and mortality have fallen in England since the introduction of cervical screening.[1,2] For the full benefits of screening to be achieved, uptake of screening should be as high as possible. However, despite the evidence about its effectiveness and even though the health system in England offers universal health care through the National Health Service (NHS) that is free at the point of delivery to all its residents, including preventive programs, cervical screening coverage varies widely among English primary care organizations. Standardized collection of data on cervical screening nationally and the availability of other data on primary care trusts (the organizations in Englands NHS responsible for ...
Recently, health screening recommendations have gone beyond screening for early-stage, asymptomatic disease to include screening for presently experienced health problems and symptoms using self-report questionnaires. We examined recommendations from three major national guideline organizations to determine the consistency of recommendations, identify sources of divergent recommendations, and determine if guideline organizations have identified any direct randomized controlled trial (RCT) evidence for the effectiveness of questionnaire-based screening. We reviewed recommendation statements listed by the Canadian Task Force on Preventive Health Care (CTFPHC), the United Kingdom National Screening Committee (UKNSC), and the United States Preventive Services Task Force (USPSTF) as of 5 September 2016. Eligible recommendations focused on using self-report questionnaires to identify patients with presently experienced health problems or symptoms. Within each recommendation and accompanying evidence ...
Clinical breast examination and referral for mammogram for women 40 years of age and older. Free service for eligible clients.. ...
Cancer prevention, screening and early detection programs have been among the most beneficial health care practices implemented in the United States, saving countless lives every year. Cancer screenings are tests performed on healthy individuals without any symptoms. The tests either prevent cancer or detect it early, when the chances for successful treatment are highest. With March being Colon Cancer Awareness Month, it is important to highlight the progress, as well as issues, surrounding
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Lung cancer is the leading cause of cancer deaths in Texas - more than breast, prostate, and colorectal cancers combined. The good news is that annual lung cancer screening with low-dose computed tomography, or LCS with LDCT, allows for lung cancer to be diagnosed at earlier stages than in the past. Most importantly, up to 80% of people with screen-detected lung cancer can be cured. Despite United States Preventive Services Task Force recommendations for LCS with LDCT in high-risk individuals and CMS coverage since 2015, Texas ranks below average for LCS among high risk individuals, with only 1.7% of those eligible receiving screening with LDCT, according to the American Lung Association.. Provider discussion and referral can have a tremendous impact on screening participation. In one study, 82% of patients reported that they would undergo LDCT lung screening if recommended by their physician. Another study found that approximately 85% of LCS-adherent patients reported trust in their provider ...
I am so happy to have found this article, which states so clearly many of the points that I have been trying to get across to family and friends on the issue of mammograms (as well as health/medical issues in general). Also, I find many of the readers comments just as valuable. I will be passing along the article and comments to many -- including my sister, who is an OB/GYN doctor and needs to hear this.. Hopefully, more and more women are questioning the risks/benefits of mammograms, especially in light of the new guidelines presented by the United States Preventive Services Task Force last year. Interestingly for me, my time to start yearly mammograms at age 40 came a few years ago, before the new guidelines. Being the type of person that I am -- doing research for myself, rather than trusting someone elses position, regardless of that persons title -- I started reading up on mammograms. Even without the data, as another reader commented, the process (compression of the breasts, radiation ...
The screening assessments were positive in 5,805/14,561(39.9%) for alcohol and 2,454/14,494 (16.9%) for drugs. We collapsed the free-text chief complaints into 50 usable categories. To identify 75% of all ED patients having positive assessments using the first strategy would require including 19 chief complaints for alcohol screening and 20 chief complaints for drug screening. Adapting the second strategy, we would need to screen at least 71% and 68% of all ED patients for alcohol and drugs respectively to identify 75% of those having positive assessments. Among all ED patients screening positive for unhealthy alcohol or drug use. N=6,698 (46.0%), Figures 1 and 2 show the cumulative proportion of positive screens detected for each strategy when presenting complaints are used to select a subset of patients to screen. The horizontal axis adds complaints one at a time in descending order of complaint sensitivity in detecting positive screens (Strategy 1), and proportion positive screens when the ...
Jessica Trevino Jones, MD, spoke to KPRC-TV Channel 2 about the importance of attending scheduled appointments for mammograms and cervical cancer screenings and warns of the possible health risks of missing these visits. Read the full story…. June 3, 2020. ...
In 2012, the United States Preventive Services Task Force recommended that men of all ages should not be routinely screened for levels of prostate-specific antigen (PSA). These are the blood tests to detect the possibility of prostate cancer.. That group now recommends that men ages 55 to 69 should talk with their doctors and make well-informed individual decisions about the potential harms and benefits of PSA screening, as well as treatment if cancer is found.. ...
The findings of the present study show that women who receive opioid prescriptions are no less likely to report undergoing recommended cancer screenings than those who do not receive such prescriptions. In models that did not account for their greater health care utilization, the results suggested a greater likelihood of breast, cervical, and colorectal cancer screenings among women prescribed opioids compared to women who were not. Adjusting for total doctors office visits showed attenuation of this effect. These fully adjusted models showed little relation between opioids and cancer screenings. This suggests that the key driver of whether women receive recommended cancer screenings is simply how often they see their doctor.. The opioid-preventive care relation was consistent in sensitivity analyses that examined different categories of opioid prescription use. These findings counter prevailing concerns that addressing pain and managing prescription opioid therapy might be detrimental to ...
A bill supporters say is essential to womens health is awaiting a decision by Governor Arnold Schwarzenegger. It would fully restore a program that provides free cancer screenings to low-income women.
Archbold Hosts Free Head and Neck Cancer Screenings Monday, April 22, 2013 According to the National Cancer Institute, its estimated that each year...
Dentist in Harrisburg provides comprehensive, high quality dental care including oral cancer screenings. Contact our office for more information.
In the wake of these reports, some groups are reviewing their current guidelines, which recommend aspirin to prevent coronary heart disease but not colorectal cancer. Were all aware of this issue, said Virginia Moyer, MD, MPH, who chairs the United States Preventive Services Task Force. The Task Force, which reviews all its guidelines on a rotating schedule, will be looking at this one, though no date has been set. It remains on the active topic list, Dr. Moyer wrote in an e-mail, and will be updated, but unfortunately, its waiting in line with a number of other important updates.. In the meantime, analysis continues in two large studies that did not show any benefit for aspirin in colorectal cancer after 10 to 12 years follow-up. Both the Womens Health Study and the Physicians Health Study looked at aspirin taken every other day rather than daily. New data from these large and rigorous studies, when available, are expected to have a substantial influence on the evolution of future ...
Destination: Healthy Skin tours 16 states this summer providing free skin cancer screenings as melanoma cases are expected to increase by 14 percent. Get checked and be healthy, for free.
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A new study finds rates of advanced prostate cancer continued to increase in men aged 50 and over in the United States, five years after the United States Preventive Services Task Force (USPSTF) recommended against prostate-specific antigen-based screening for all men.
The Centers for Medicare and Medicaid Services (CMS) has released a proposed decision memo for adding hepatitis B screening as a covered Medicare preventive service. CMS is proposing to cover hepatitis B screening at no cost to Medicare beneficiaries who are at high risk as defined by the United States Preventive Services Task Force. To be covered by Medicare, the test would need to be ordered by the beneficiarys primary care physician or practitioner within the context of a primary care setting and performed by an eligible Medicare provider. CMS is now accepting public comments in response to its proposed decision. The deadline to submit comments is August 6, 2016. You can read this decision memo here. You can submit public comments by clicking the comment button at the top of the decision memo. ...
Mammography rates did not decrease among women aged |40 years after publication of the USPSTF recommendations in 2009, suggesting that the vigorous policy debates and coverage in the media and medical literature have had an impact on the adoption of these recommendations.
Vitamin D and calcium are dietary requirements, but its unclear how much is best for us. New draft findings by the United States Preventive Services Task Force conclude that for healthy, postmenopausal women, daily supplementation with low levels of vitamin D - up to 400 international units - combined with 1,000 milligrams of calcium, does not reduce fracture risk.
The United States Preventive Services Task Force recommends low-dose aspirin after 12 weeks gestation for women at high-risk of preeclampsia.
After an influential task force of experts said evidence didnt support some cancer screenings, it became the target of lawmakers, including Rep. Tom Price and others with health industry ties.
Getting regular medical checkups (e.g. by a service like Werlabs) is not something that everyone does. Even when they have the health insurance that covers them.. These five reasons to get regular medical checkups, however, could prove to you why this is important and why you should be getting them every year.. Prevention is important - If most illnesses are caught early enough, curing them is relatively simple. The longer you wait to see a doctor, however, the more likely it is that any illness you have has developed to the extent that it could be difficult to cure.. Get regular medical checkups and worrying about an illness developing could be a thing of the past.. Cancer screenings - Various types of cancer screenings will be included in any regular medical checkup. As cancers that are caught early are much easier to cure than those that are not, it is important to have regular cancer screenings.. Annual EKGs - Many people have heart problems yet do not know that they do. An annual EKG done ...
Two studies help clarify the risks and benefits of breast cancer-screening strategies, and explain the USPSTF final recommendation.
The earlier breast cancer is found, the easier it is to treat. And mammogram, X-rays of the breast, can detect tumors before they are large enough to feel. The American Cancer Society recommends yearly mammogram beginning at age 40 for women at average risk. While the U.S. Preventive Services Task Force recommends a screening mammogram every two years from age 50 to 74. It also notes that before age 50, each woman should check with a doctor to find out what screening schedule is right for her, considering the potential benefits and harms from screening. ...
New findings from a Decision Analysis for the US Preventative Services Task Force (USPSTF) suggest that routine colorectal cancer screenings can be stopped in patients over the age of 75.
Join NBC 5 and the National Kidney Foundation at the Kidney Early Evaluation Program (KEEP) Screening on Saturday, October 8, from 9:00 a.m. to 1:00 p.m. at the Inspiring Temple of Praise in Fort Worth.
The earlier breast cancer is found, the easier it is to treat. And mammograms, X-rays of the breast, can detect tumors before they are large enough to feel. The American Cancer Society recommends yearly mammograms beginning at age 40 for women at average risk. While the U.S. Preventive Services Task Force recommends a screening mammogram every two years from age 50 to 74. It also notes that before age 50, each woman should check with a doctor to find out what screening schedule is right for her, considering the potential benefits and harms from screening ...
According to a report by the US Centres for Disease Control and Prevention, about 1 in 10 women, aged 21 to 65 have gone for years without screening for cervical cancer.
Most screen-detected breast cancer survivors have been either overdiagnosed or diagnosed early without effect on mortality risk, a probability modeling study suggested.
The U.S. Preventative Services Task Force (USPSTF) approved annual screening with low-dose CT for individuals at high risk for lung cancer.. The task force recommended annual scans for adults aged 55 to 80 who have a smoking history of 30 pack-years (= 1pack/day for 30 years, 2 packs/day for 15 years) and who currently smoke or who have quit within the past 15 years and who have no symptoms of lung cancer.. The recommendations are in large part based on the National Lung Screening Trial (NLST) in the United States, which compared lung cancer screening methods (chest xray vs. CT scans) in current and former smokers. The results showed that people who received low-dose CT scans had a lower risk of dying from lung cancer than people who received standard chest X-rays.. The USPSTFs recommendation is on par with previous recommendations for screening for breast, colon and cervical cancers - for which survival has increased dramatically following wide-spread screening programs. it is felt that the ...
Breast cancer screening saves live and is worth the cost, despite findings released by the Department of Health and Cancer Research UKs review.
The main goal of this analysis was to generate estimates of self-report accuracy for specific cancer-screening procedures that could then be applied to national survey data to improve the accuracy of national prevalence estimates for colorectal cancer screening and screening for other cancers, estimates that are largely based on self-reports. We examined sensitivity as a measure of underreporting and examined both specificity and positive predictive value as measures of overreporting.. We found that estimates of self-report accuracy varied substantially from study to study, making it difficult to arrive at stable estimates of self-report accuracy for different procedures and accuracy measures. Study heterogeneity could be the result of many different factors related to sample socioeconomic and cultural characteristics, the context in which self-reports were elicited (e.g., survey mode and location, wording of question), and the completeness and accuracy of documentation of true screening ...
Routine colon cancer screening is often not recommended for men over age 75 unless they have had precancerous polyps before or have a family history of colon…
A federal government task force recommended Monday that women do not get routinely screened for ovarian cancer because doing so can put them at increased risk for unnecessary harm, such as major surgery.
Pap test every 3 years for women ages 21-29; for women 30-65, Pap test and HPV test every 5 years or Pap test alone every 3 years. Women at average risk should not be screened more than once every 3 years. Testing may be stopped at age 65 or 70 for women who have 3 or more normal Pap tests in a row and no abnormal test results in 10 years. If you have had your cervix and uterus removed, ask your health care provider if you need to continue screening ...
(BPT) - In the early part of the COVID-19 pandemic, many areas of the country banned nonessential medical procedures in an effort to slow the spread of the disease. As a result, many physicians saw …
Learn about the colonoscopy screening offered by UPMC Hamot, which can detect growths in the colon or rectum that can be removed before they become cancerous.
Scientists have been trying to find a quick, noninvasive cancer-screening test for years. Most doctors now rely on blood tests to detect cancer-and usually only if they suspect you have the disease. Even then, it can take as long as two weeks to get results back.. That could be changing soon. Researchers from the University of California at Los Angeles announced at a conference that theyve developed a new test that can detect cancer in a single drop of saliva. With just one mouth swab, doctors would be able to detect traces of cancer cells in 10 minutes. Quick results would mean faster treatment, which could be life-saving for such types of deadly conditions as pancreatic cancer. ...
With almost $200 million in NIH funding, UAB scientists are at the forefront of research that is shaping the future of health and healthcare.
Our Vanishing Legacy' Screening". The New York Preservation Archive Project. Archived from the original on March 12, 2013. ... Lenox, Massachusetts: Lenox Library Association. ISBN 978-1584653745. Borak, Jeffrey. "It's a star-studded 200th birthday for ... S. G. Hyatt of Lee, Massachusetts. Hyatt attended Lee High School for secondary education, and attended Boston University from ... Gordon and Carole live in New York City and Stockbridge, Massachusetts. The conservatory of their Stockbridge home has been ...
The on-screen blood was real in some cases, such as the scene in which Leatherface feeds "Grandpa". The crew had difficulty ... ISBN 978-0-485-30095-6. Wells, Alan; Hakanen, Ernest A. (1997). Mass Media & Society. Greenwood Publishing Group. p. 476. ISBN ... It screened nationally in the United States as a Saturday afternoon matinée and its false marketing as a "true story" helped it ... After a screening in the Directors' Fortnight section of the 2014 Cannes Film Festival, this was also released on DVD and Blu- ...
Her first credited screen role came later that year when she played Dibs Downing in Our Hearts Were Growing Up. She had another ... Massachusetts, Boston. August 29, 1947. p. 21. Retrieved September 14, 2018 - via CS1 maint: discouraged ... Mary Hatcher (June 6, 1929 - April 3, 2018) was an American coloratura soprano and actress whose screen career spanned the ... CS1 maint: discouraged parameter (link) Corby, Jane (January 15, 1950). "Screenings". The Brooklyn Daily Eagle. New York, ...
... is a mass entertainer". Screen. 5 February 1971. p. 22. Kantha, Sachi Sri (27 December 2019). "MGR Remembered - Part 54 , An ... Screen criticised the photography, choreography, art direction and music, saying that "With these credits more sophisticated, ...
doi:10.1093/screen/32.3.286 - via Oxford University Press Journals. "Civil Brand (2002) and the Prison Industrial Complex". ... Maiden, Massachusetts: Blackwell. 2001. ISBN 9780631222392. OCLC 44683443. "Jacqueline Bobo (faculty profile)". Department of ... Bobo, J.; Seiter, E. (Fall 1991). ""Black feminism and media criticism: "The Women of Brewster Place"". Screen. 32 (3): 286-302 ... March 2018 - via EBSCOhost Communication & Mass Media Complet. Articulation and hegemony: Black women's response to the film ...
"Killed Palestinian Journalist Had Passed U.S. Screening For Grant Funds". Retrieved 28 April 2018. Al-Sayyad, Yasmine ... "Gaza buries journalist killed while covering mass protests". CBS News. Associated Press. 7 April 2018. Retrieved 28 April 2018 ... "Ai Weiwei's 'Human Flow' assistant cameraman shot dead by Israeli military". Screen. Retrieved 28 April 2018. " ...
"Screening of 'Phantom Tollbooth' Documentary". Amherst, Massachusetts: Hampshire College. September 10, 2013. Retrieved March 9 ... Juster lived in Massachusetts during his later years. His wife, Jeanne, died in October 2018 after 54 years of marriage. ... Springfield, Massachusetts. Retrieved March 9, 2021. Juster, Norton (2008). Sourpuss and Sweetie Pie. Michael Di Capua Books. ... Juster died on March 8, 2021, at his home in Northampton, Massachusetts. He was 91, and suffered from complications of a stroke ...
A screening policy (including prenatal screening and abortion) intended to reduce the incidence of thalassemia exists in both ... In years to come, the ERO collected a mass of family pedigrees and concluded that those who were unfit came from economically ... Cambridge, MA: Harvard University Press. pp. 208-216. ISBN 978-0-674-02424-3. Joanna McMillan (2006-01-13). Sex, Science and ... When Nazi administrators went on trial for war crimes in Nuremberg after World War II, they attempted to justify the mass ...
It produces dose-dependent increases in muscle mass and decrease in body fat, and is under investigation for the treatment of ... High Throughput Screening. 9 (3): 187-96. doi:10.2174/138620706776055548. PMID 16533152. Thevis M, Wilkens F, Geyer H, Schänzer ... Rapid Communications in Mass Spectrometry. 20 (22): 3393-402. Bibcode:2006RCMS...20.3393T. doi:10.1002/rcm.2758. PMID 17051614 ...
"Cinema of Fear Screen Grabs: A Nightmare on Elm Street 3: Dream Warriors". Mezco Toyz. Archived from the original on December ... Langenkamp, Heather (2011-08-08). "Exclusive Interview With Heather Langenkamp , STATIC MASS EMPORIUM" (Interview). Interviewed ... Adrienne Tyler (September 14, 2019). "Patricia Arquette's Nightmare On Elm Street Role Explained". Screen Rant. Retrieved ... instead insisting that the common element of a bogeyman in their dreams is the result of mass hysteria and "the by-products of ...
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Wiley-Blackwell, Massachusetts. Nank, John. "George L. San Jose". Advertising PR Media. Smart Business. Retrieved 18 July 2012 ... Screen Magazine. Retrieved 18 July 2012. Klein, Sarah A. "Beyond Sombreros". This Week's Crain's Focus. Crain's Chicago ...
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IndieWire's Jamie Righetti pointed out that Billy's obscene phone calls, "ma[de] it clear that some horrors are all too common ... Screen Rant. Retrieved March 5, 2020. Delaney, Eamon (September 4, 2000). "Campbell Armstrong: Making It Whole Again". ... ISBN 978-1-935254-97-3. Willis, John; Monush, Barry (May 1, 2010). Screen World 2007. Hal Leonard. ISBN 978-1-55783-729-5. ... July 22, 2005). "Black Christmas". On Screen!. Canadian Television Fund. CS1 maint: discouraged parameter (link) Page, Aubrey ( ...
It also screened at the New York Film Festival on September 20, 2020. It was released theatrically on October 9, 2020, and on ... Ehrlich, David (3 February 2020). "'Time' Review: A Poignant and Monumental Portrait of Mass Incarceration in America". ... Morgan, Jillian (21 February 2020). "Amazon Studios acquires Garrett Bradley Sundance doc "Time"". Real Screen. Retrieved 13 ... Film Independent Spirit Awards: 'Never Rarely Sometimes Always,' 'Minari,' 'Ma Rainey's Black Bottom,' 'Nomadland' Top ...
Deckelmeier, Joe (May 31, 2019). "Juliette Lewis & Diana Silvers Interview: Ma". Screen Rant. Archived from the original on ... Ma was a box-office success, grossing over $60 million worldwide, and was nominated for a Saturn Award for Best Thriller Film. ... Her first on-screen appearance was an uncredited bit part in Bronco Billy (1980), in which her father played a supporting role ... "Ma". Box Office Mojo. Retrieved September 28, 2019. Hammond, Pete (July 15, 2019). "'Avengers: Endgame', 'Game Of Thrones' Lead ...
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Kevin Ma (November 29, 2013). "Great Passage tops 38th Hochi Film Awards". Film Business Asia. Archived from the original on ... Mark Adams (19 March 2013). "The Great Passage". Screen International. Retrieved 17 July 2013. Gary Goldstein (December 12, ... Kevin Ma (January 17, 2014). "Kore-eda, Ishii, Yamada lead Japan awards". Film Business Asia. Archived from the original on ... Kevin Ma (March 7, 2014). "The Great Passage wins Japan Academy Prize". Film Business Asia. Archived from the original on ...
Crisler, B. r (April 26, 1940). "THE SCREEN; Strange Cargo' Lands at Capitol--Palace Has 'Ma! He's Making Eyes at Me'--Foreign ... Gable died of a heart attack; his final on-screen appearance was of an aging cowboy in The Misfits, released posthumously in ... A popular combination on-screen and off, Gable and Harlow made six films together in five years. Their final film together was ... The couple, who lovingly referred to each other as "Ma and Pa", owned a menagerie of animals and raised chickens and horses ...
Maiberg, Emanuel (18 August 2014). "Mini Metro turns the headache of mass transportation into fun". Kill Screen. Kill Screen. ... Gach, Ethan (24 November 2015). "Mini Metro makes mass transportation sublime". Kill Screen. Kill Screen. Archived from the ... "Learn the science of the subway in Mini Metro". Kill Screen. Kill Screen. 12 November 2015. Archived from the original on 20 ... Kill Screen editor, Ethan Gach commended the game for its simplicity and elegance, having combined interactive aesthetics with ...
Kismat (1968) Music CD at Sa Re Ga Ma. Sa Re Ga Ma. Retrieved: 3 September 2011. Kismat (1968) Songs in iTunes. iTunes Apple. ... Men In Drag in Screen magazine. Screen India. Retrieved: 9 September 2011. Kismat (1968) Music Record Review. Retrieved: 3 ... Biswajeet is one of the first heroes in Bollywood to be dressed as a woman on screen for the song Kajra Mohabbat Wala. This ...
Cambridge, Massachusetts: MIT Press. 2013. ISBN 978-0262019057. Nina C. Ayoub. "Screen Spleen." The Chronicle Review, March 18 ... Cambridge, Massachusetts: MIT Press. 2009. ISBN 978-0262013376. The Art of Failure: An Essay on the Pain of Playing Video Games ... Cambridge, Massachusetts: MIT Press. 2005. ISBN 978-0262101103. A Casual Revolution: Reinventing Video Games and their Players ... He has previously worked at the New York University Game Center, Comparative Media Studies at Massachusetts Institute of ...
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Bosley Crowther (October 18, 1949). "The Screen; German Drama at World". The New York Times. List of the 50 highest-grossing ... "The Blum Affair (Affaire Blum): Synopsis". DEFA Film Library, University of Massachusetts Amherst. Retrieved 25 May 2015. ...
Boston, MA. November 21, 2002. "Screen Candy and Food For Thought". Bay Windows. Boston, MA. May 1, 2003. Hornblow, Deborah ( ... Boston, MA. May 6, 2004. "In Brief". Knoxville News Sentinel. Knoxville, TN. May 25, 2004. p. B2. "Special Screenings". ... Northhampton, MA. February 12, 2004. p. D3. "Calendar: Music". Daily Hampshire Gazette. Northhampton, MA. February 13, 2004. p ... Screening sponsored by the Women's Studies Department, Massachusetts Institute of Technology (November 23, 2002) London Lesbian ...
Screen Daily. Ma, Kevin (2015-09-26). "Lost in Hong Kong sets China opening day record". Film Business Asia. "港囧 到底有乜港味可以重来?". ... It debuted with an unprecedented 100,000+ first-day screenings on nearly 20,000 screens-and surpassed all newcomers by ... In China, it made $1.8 million from midnight screenings and $32 million on its opening day on Friday, September 25, 2015, which ... During its opening weekend it grossed an estimated US$106.8 million from a massive 284,000 screenings in three days becoming ...
Noh, Jean (6 February 2014). "Gaga launches sales on Tetsuya Nakashima's The World of Kanako". Screen International. Kevin Ma ( ... CS1 maint: discouraged parameter (link) Kevin Ma (8 July 2014). "Maleficent dethrones Frozen in Japan". Film Business Asia. ...
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a b c d e f g h DynaMed Plus [Internet]. Ipswich (MA): EBSCO Information Services. 1995 - . Record No. 113880, Groin hernia in ... Prevention and screening[edit]. Most indirect inguinal hernias in the abdominal wall are not preventable. Direct inguinal ... 113880, Groin hernia in adults and adolescents; [updated 2017 Nov 27, cited Nov 27, 2017]; [about 28 screens]. Available from ... DynaMed Plus [Internet]. Ipswich (MA): EBSCO Information Services. 1995 - . Record No. ...
... can register on urine drug screens as either methamphetamine, amphetamine, or both, depending on the ... Molar mass. 149.23 g·mol−1. 3D model (JSmol). *Interactive image. SMILES ...
Screening. No major organization recommends universal screening for diabetes as there is no evidence that such a program ... "In Feinglos MN, Bethel MA (eds.). Type 2 diabetes mellitus: an evidence-based approach to practical management. Contemporary ... The American Diabetes Association recommends screening those who have a BMI over 25 (in people of Asian descent screening is ... "Draft Recommendation Statement Screening for Abnormal Glucose and Type 2 Diabetes Mellitus". U.S. Preventive Services Task ...
Sliwińska MA. [The role of lamins and mutations of LMNA gene in physiological and premature aging]. Postepy Biochem. 2007, 53 ( ... Identification of 12-lipoxygenase interaction with cellular proteins by yeast two-hybrid screening. Biochemistry. March 2000, ...
Drivalos A, Papatsoris AG, Chrisofos M, Efstathiou E, Dimopoulos MA (2011). "The role of the cell adhesion molecules (integrins ... "Wnt inhibitor screen reveals iron dependence of β-catenin signaling in cancers". Cancer Res. 71 (24): 7628-39. doi:10.1158/0008 ...
Meester-Smoor MA, Janssen MJ, Grosveld GC, et al. (2008). "MN1 affects expression of genes involved in hematopoiesis and can ... 1996). "Development of a screening set for new (CAG/CTG)n dynamic mutations". Genomics. 32 (1): 75-85. doi:10.1006/geno. ... Meester-Smoor MA, Molijn AC, Zhao Y, et al. (2007). "The MN1 oncoprotein activates transcription of the IGFBP5 promoter through ... van Wely KH, Molijn AC, Buijs A, Meester-Smoor MA, Aarnoudse AJ, Hellemons A, den Besten P, Grosveld GC, Zwarthoff EC (February ...
Semple later claimed that Switzer had been issued a number through an "oversight" in the entry screening process.[21] ... Boston, Massachusetts, United States 2nd 2:51:37[24] References[edit]. .mw-parser-output .reflist{font-size:90%;margin-bottom: ...
Free Local Screenings of "GOODWILL" in New Jersey. *Website of Documentary Film "FLYING WITH EMILIO" by J & J Video Productions ... he flew to Lowell Massachusetts to dedicate a new field there. He went at the request of Edith Nourse Rogers who was ...
Choi JH, Croyle MA (December 2013). "Emerging targets and novel approaches to Ebola virus prophylaxis and treatment". BioDrugs ... Virus persistence in semen for over a year has been recorded in a national screening programme.[64] Ebola may also occur in the ... Olivero J, Fa JE, Real R, Márquez AL, Farfán MA, Vargas JM, et al. (30 October 2017). "Recent loss of closed forests is ... but might be difficult to prepare as a weapon of mass destruction because the virus becomes ineffective quickly in open air.[ ...
Crisp, P. (1982). "The use of an evolutionary scheme for cauliflowers in screening of genetic resources". Euphytica. 31 (3): ... "Center for Agriculture, Food and the Environment, College of Natural Sciences, University of Massachusetts at Amherst, USA. 14 ...
Early and Periodic Screening, Diagnostic and Treatment (EPSDT) is a mandatory Medicaid program for children that focuses on ... A sequence of two high-profile studies by a team from the Massachusetts Institute of Technology and the Harvard School of ... If a condition requiring treatment is discovered during an oral screening, the state is responsible for paying for this service ... Clinton, Joshua D.; Sances, Michael W. (November 2, 2017). "The Politics of Policy: The Initial Mass Political Effects of ...
... when preparation for Operation Barbarossa involved the planning of mass execution, mass expulsion, and starvation - to dwarf ... via book excerpt in full screen. On November 4, 1943, Globocnik wrote to Himmler from Trieste: "I have, on Oct. 19 ... More Jews were killed at Treblinka than at any other Nazi extermination camp apart from Auschwitz.[77] By the time the mass ... the largest mass shooting of Soviet Jews took place on 29-30 September in the ravine of Babi Yar, near Kiev, where more than ...
a b Massachusetts (State). Legislature. General Court. 1887 Chap. 0183. An Act to Secure Proper Sanitary Provisions in ... One option would be to continue to offer urinals in rows, with separation by screens. However, it is questionable whether the ... the Massachusetts statute was definitely not the first law mandating sex-separation in Massachusetts. ... University of Massachusetts Stonewall Center. Archived from the original (PDF) on March 19, 2015. Retrieved November 19, 2016. ...
The original video contained no title screen and was roughly edited. The video featured a medley of footage from Success-N-Life ... the Tulsa-based marketing firm handling Tilton's mass mailings, to discuss a proposal sent by Anthony to Response Media about ...
"Lenetix Launches Screening Study Of New Down Syndrome Test". Archived from the original on March 17, 2010 ... The CEO and founder of the company held residency positions in oncology at Massachusetts General Hospital and in emergency ...
The digestive system of the octopus begins with the buccal mass which consists of the mouth, pharynx, radula and salivary ... The pupil can be adjusted in size and a retinal pigment screens incident light in bright conditions.[22] ... The octopus (along with cuttlefish) has the highest brain-to-body mass ratios of all invertebrates, and is also greater than ... and was estimated to have had a live mass of 75 kg (165 lb).[19][20] The smallest species is Octopus wolfi, which is around 2.5 ...
325,000 from 481 IMAX screens and premium large-format screens from late night showings, which began at 7 pm,[41][42] and an ... Brad Brevet (20 September 2015). "'Maze' and 'Mass' Top Box Office, but 'Everest' and 'Sicario' are the Story". Box Office Mojo ... Screen Actors Guild Awards[59] Outstanding Performance by a Stunt Ensemble in a Motion Picture Nominated ... "The 22nd Annual Screen Actors Guild Awards". Archived from the original on 22 December 2015. Retrieved 16 December 2015.. ...
... that former FBI director James Comey used Niebuhr's name as a screen name for his personal Twitter account. Comey, as a ... Stockbridge, Massachusetts, U.S.. Education. Elmhurst College. Eden Theological Seminary. Yale Divinity School. ...
Boston, Massachusetts. 2004 Democratic National Convention[38]. August 29, 2004. New York City, New York. 2004 Republican ... A new set was introduced on May 2, 2010, featuring video screens and library-style bookshelves; David Gregory would preview the ... and unveiled a new set consisting of large video screens mostly used to display Washington scenery, satellite interview ... guests to be featured during each week's broadcast using a large video screen. Different, modified intro music was also ...
Seltzer EG, Gerber MA, Cartter ML, Freudigman K, Shapiro ED (February 2000). "Long-term outcomes of persons with Lyme disease" ... The case definition now includes the use of Western blot without prior ELISA screen.[227] ... Williams, Carolyn (2007). Infectious disease epidemiology : theory and practice (2nd ed.). Sudbury, Mass.: Jones and Bartlett ... Wormser GP, Masters E, Nowakowski J, McKenna D, Holmgren D, Ma K, Ihde L, Cavaliere LF, Nadelman RB (October 2005). " ...
Hondras MA, Linde K, Jones AP (2005). Hondras, Maria A, ed. "Manual therapy for asthma". Cochrane Database of Systematic ... and disease prevention/early screening advice.[72] ...
Quader MA, Sawmiller CJ, Sumpio BE (2000). "Radio Contrast Agents: History and Evolution". Textbook of Angiology. pp. 775-783. ... screening tests, X-ray, CT, MRI, PET, bone scan, ultrasonography, mammography, fluoroscopy. ... He noticed a faint green glow from the screen, about 1 metre away. Röntgen realized some invisible rays coming from the tube ... These electron are then focus using electron lenses inside the intensifier to an output screen coated with phosphorescent ...
Audiologists also run neonatal hearing screening programme which has been made compulsory in many hospitals in US, UK and India ... diploma programs which has resulted in dilution of services particularly in hearing aid dispensing and there have been mass ... They also help design and implement personal and industrial hearing safety programs, newborn hearing screening programs, school ... hearing screening programs, and provide special fitting ear plugs and other hearing protection devices to help prevent hearing ...
Current mass extinction". In Elewa, Ashraf M. T. (ed.). Mass Extinction. pp. 191-194. doi:10.1007/978-3-540-75916-4_14. ISBN ... "Holistic screening of collapsing honey bee colonies in Spain: a case study". BMC Research Notes. 7: 649. doi:10.1186/1756-0500 ... Winchester, MA: Allen & Unwin. ISBN 978-0-04-551068-9. .. *^ Davis, M. B. (1976). "Pleistocene biogeography of temperate ... The Holocene extinction, otherwise referred to as the sixth mass extinction or Anthropocene extinction, is an ongoing ...
In mass mediaEdit. Much of the film Love in the Time of Cholera takes place in the historic, walled city of Cartagena in ... Some screen shots showed the Magdalena River and the Sierra Nevada de Santa Marta mountain range. ...
When his first child was about to be born, he attended Mass in Detroit, and put his last $7.00 in the offering bin. He prayed ... and a movie trailer that runs on 20,000 screens nationwide, runs from Thanksgiving until the New Year. The campaign was created ...
Gas storage in activated carbons is an appealing gas storage method because the gas can be stored in a low pressure, low mass, ... Air is then introduced to burn out the gasses, creating a graded, screened and de-dusted form of activated carbon. This is ...
1363 (D. Mass. 1969)), the United States Court of Appeals for the Second Circuit, and the Supreme Court of the United States ( ... "Screen: 'I Am Curious (Yellow)' From Sweden - The New York Times". Retrieved 2018-09-19 ... In 1969, the film was banned in Massachusetts for being pornographic and Boston police seized the film reels for I Am Curious ( ... After proceedings in the United States District Court for the District of Massachusetts (Karalexis v. Byrne, 306 F. Supp. ...
Norwood, MA: The Plimpton Press. *^ a b Christie, A., & Barling, J. (2011). A short history of occupational health psychology: ... Day, A.L, & Catano, V.M. (2006) Screening and selecting out violent employees. In E.K. Kelloway, J. Barling, & J.J. Hurrell, Jr ... 308-323). Northampton, MA, US: Edward Elgar Publishing. doi:10.4337/9780857933843.00030 *^ Burgard, S.A., Brand, J.E., & House ... "screening out applicants [for jobs] who may be prone to engaging in aggressive behavior,"[147] suggesting that aggression- ...
Electron screening of the positive hydrogen nuclei by the negative electrons in the palladium lattice was suggested to the 2004 ... Shanahan, Kirk L. (23 May 2002), "A systematic error in mass flow calorimetry demonstrated", Thermochimica Acta, 382 (2): 95- ... The Massachusetts Institute of Technology (MIT) announced on 12 April 1989 that it had applied for its own patents based on ...
They don't have a touch screen so readers navigate with the phone keys. There is now a simulator so you can see what it looks ... This meant some functions did not save changes and mass messages were delayed. This did not affect wiki edits. [114] ...
Native mass spectrometry is applied in our group in a combined approach of phenotypic screening and target screening, which we ... Dont hesitate to contact us for more information on our Mass Spectrometry screening services - please get in touch with Mass ... GRIDDs Mass Spectrometry screening helped me discover a "hidden gem" in a fragment-based drug discovery research campaign. ... Home > Griffith Institute for Drug Discovery > Unique resources > Mass Spectrometry Screening Platform ...
Looking for screenings events in Somerville? Whether youre a local, new in town, or just passing through, youll be sure to ... Share FREE screening of Our Latin Thing - 50 years of Fania All Stars with your friends.. Save FREE screening of Our Latin ... Share FREE screening of Our Latin Thing - 50 years of Fania All Stars with your friends.. Save FREE screening of Our Latin ... Share Some Like It Hot Film Screening with your friends.. Save Some Like It Hot Film Screening to your collection.. ...
Automated tandem mass spectrometry for mass newborn screening for disorders in fatty acid, organic acid, and amino acid ... Laboratory integration and utilization of tandem mass spectrometry in neonatal screening: a model for clinical mass ... Increasingly, tandem mass spectrometry (MS/MS) is being used for newborn screening because this laboratory testing technology ... University of Massachusetts Medical School. Boston, Massachusetts Gary L. Hoffman. Wisconsin State Laboratory of Hygiene. ...
This video explains the at-home option for colon cancer screening. If youre 50 or over, ask your doctor about screening. When ...® is a registered service mark of the Commonwealth of Massachusetts. ... transcript Colon Cancer Screening Saves Lives - English, 30 seconds. ...
This exciting new MA combines theory and practice, with an emphasis on encouraging students academic skills and creativity (in ... CKE02 MA in Film and Screen Media (Full-time). The MA in Film and Screen Media is a one-year taught course that offers students ... Ruth Harrington, MA in Film Studies (2006). Now a Teacher. I knew upon entering into the MA that I wanted to be a secondary ... The MA in Film and Screen Media is open to candidates with a BA degree in a Humanities subject, who have taken some ...
Effective Hearing Loss Screening in Primary Care: The Early Auditory Referral-Primary Care Study Philip Zazove, Melissa A. ... Cancer-Specific Mortality, All-Cause Mortality, and Overdiagnosis in Lung Cancer Screening Trials: A Meta-Analysis Mark H. ... Health Benefits and Cost-Effectiveness of Asymptomatic Screening for Hypertension and High Cholesterol and Aspirin Counseling ...
Accurate Inclusion Mass Screening. Jacob D. Jaffe, Hasmik Keshishian, Betty Chang, Theresa A. Addona, Michael A. Gillette, ... Accurate Inclusion Mass Screening. Jacob D. Jaffe, Hasmik Keshishian, Betty Chang, Theresa A. Addona, Michael A. Gillette, ... Accurate Inclusion Mass Screening. A Bridge from Unbiased Discovery to Targeted Assay Development for Biomarker Verification. ... The boxed portion of the schematic illustrates the selectivity power of accurate mass screening and how the MS/MS spectra are ...
MA Screen: Acting provides training for screen actors interested in character-led storytelling. As part of the Performance ... MA Screen: Acting promotes collaborative, joined-up thinking in the creative process of screen-based fiction. ... MA Screen: Acting provides a rigorous conservatoire training, focused on performance for the screen. ... MA Screen: Acting is offered in full-time mode which runs for 45 weeks over 12 months. You will be expected to commit 40 hours ...
Thanks, your survey has been submitted to the team!. If you would like to continue helping us improve, join ... Ann Lowery, 617/292-5846, [email protected] Mike DiBara, 508/767-2885, [email protected] ...® is a registered service mark of the Commonwealth of Massachusetts. ... working on behalf of the Massachusetts Department of Environmental Protection (MassDEP) and the Massachusetts Clean Energy ...
New Mass-Screening Method Finds Additional Environmental Risks for Diabetes. The first environment-wide association study ... With mass, population-based assessments, that could change, both in the speed and breadth of figuring out environmental roles ... In a study, published online May 20 in the journal PLoS ONE, they describe a new, environmental-based risk factor screening for ... After controlling for age, sex, body mass index, ethnicity and socioeconomic status, the group found that those with high ...
Mass E Bhat is a portrait of a developing nation through the eyes of its children. This screening will be followed by a Q&A ... Screening: Mass E Bhat + Q&A. Screening Monday 13 October 2014, 7:00 PM ... This screening will be followed by a Q&A with directors Hannan Majid and Richard York. ... Mass migration from villages results in densely populated slums and crowded factories. Across the country, 7.9 million children ...
Hyderabad Airport Gets UNICEF-funded Mass Fever Screening System Read it! ... Hyderabads Rajiv Gandhi International Airport RGIA has received a UNICEF-funded a mass fever screening system to further ... enhance the efficacy of screening of passengers in view of COVID-19 pandemic, the airport operator announced on Sunday.... ... has received a UNICEF-funded a mass fever screening system to further enhance the efficacy of screening of passengers in view ...
A new coronavirus test could be a key but imperfect step toward the kind of mass screening deemed essential to reopening ... Many companies are working on versions that would be more accurate, easier to use and more suitable for mass screenings. ... toward the kind of mass screening that experts say is essential to returning millions of Americans to school and work. ... screens for new infections but in a different way. It looks for protein traces of the virus - known as antigens. The same ...
Our MA combines the study of mainstream and experimental film, contemporary television and the video-essay form, and includes ... this MA is not only about studying film theory but also about immersing yourself in the wealth of screen-related events and ... PostgraduateFilm and Screen Cultures. Apply for this course *Study film, television, and new media alongside world-leading ... This cutting-edge MA offers the opportunity for advanced studies in television and new media. Taught by leading figures in the ...
Patient, Clinician, and Communication Factors Associated with Colorectal Cancer Screening Alex H. Krist, Camille J. Hochheimer ... Fecal Immunochemical Test (FIT) for Colon Cancer Screening: Variable Performance with Ambient Temperature Chyke A. Doubeni, ...
PRNewswire/ -- Research and Markets has announced the addition of the NewBorn Screening Market by Test Type, Technology, ... 5 Newborn Screening Market, By Test Type 6 Newborn Screening Market, By Technology 7 Newborn Screening Market, By Product Type ... Newborn screening is a test in which the newborns are screened for a panel of inborn diseases that can lead to disabilities or ... Global NewBorn Screening (Tandem Mass Spectrometry, Immunoassay, Enzyme Assay, Electrophoresis, Pulse Oximeter) Market - ...
Youll cover the theory and practice of screen translation, and explore a variety of international and European films. Your ... Our MA prepares you for a career in subtitling or translating. ... With an MA in Screen Translation you will be employable as a ... The MA Im taking is one of the few Screen Translation MAs being taught in the UK. I love it because Im passionate about ... Our MA prepares you for a career in subtitling or translating. Youll cover the theory and practice of screen translation, and ...
How can the MA Scriptwriting support your career?. This MA prepares you to go on to a wide array of careers in radio, web, TV ... Writing for Stage, Screen and Audio (30 credits) - Compulsory This module will allow you to produce four pieces of work. Youll ... Why study MA Scriptwriting at Middlesex University?. This course is aimed at potential and current practitioners who want to ... How is the MA Scriptwriting taught?. The course is predominantly taught via seminars and workshops, where youre encouraged to ...
Rapid screening for taxanes by tandem mass spectrometry. Download Prime PubMed App to iPhone, iPad, or Android ... Rapid screening for taxanes by tandem mass spectrometry.. Anal Chem. 1992 Oct 15; 64(20):2313-5.AC ... Rapid Screening for Taxanes By Tandem Mass Spectrometry. Anal Chem. 1992 Oct 15;64(20):2313-5. PubMed PMID: 1361307. ... TY - JOUR T1 - Rapid screening for taxanes by tandem mass spectrometry. AU - Hoke,S H,2nd AU - Wood,J M, AU - Cooks,R G, AU - ...
This application brief demonstrates to successfully carry out a broad scope of pesticide screening in environmental waters ... Applied Benefits of Narrow Mass Windows for TOF Screening. Applied Benefits of Narrow Mass Windows for TOF Screening ... which removed any additional peaks that were close to the exact mass of fenuron. This demonstrates the stability of mass ... were used to rapidly screen treated sewage effluent that had been extracted using Oasis HLB SPE Cartridges. A generic screening ...
Search for Screening Rooms / Projection Rooms in cities in Massachusetts:. *Boston, MA Screening Rooms / Projection Rooms ... MA Screening Rooms / Projection Rooms. Search for Screening Rooms / Projection Rooms in related areas:. *California Screening ... Massachusetts Assistant Editors in Somerville, Massachusetts Audio / Sound Transfers in Somerville, Massachusetts Blu-Ray / DVD ... Massachusetts Film / Video Transfers in Somerville, Massachusetts Film Editors in Somerville, Massachusetts HD / UHD / 4K / ...
Multiplex PCR/mass spectrometry screening of biological carcinogenic agents in human mammary tumors.. Peng J1, Wang T2, Zhu H2 ... We also screened for the viruses in blood samples from the patients and 96 female blood donor volunteers (group 3). ... Breast cancer; Epstein-Barr virus; Human papillomavirus; MALDI-TOF mass spectrometry; Merkel cell polyomavirus; Polyomavirus ...
The method improves the current protocols that use tandem mass spectrometry by assuring accurate and consistent results at the ... A method for screening newborns using electrospray tandem mass spectrometry. ... Neo Gen Screening, Inc.. Clinical method for the genetic screening of newborns using tandem mass spectrometry. ... Naylor, E., et al; Automated Tandem Mass Spectrometry for Mass Newborn Screening for Disorders in Fatty Acid, Organic Acid, and ...
Tandem mass spectrometry in newborn screening: a primer for neonatal and perinatal nurses.. Banta-Wright SA1, Steiner RD. ... Since 1961, newborn screening for errors of metabolism (EM) has improved the diagnosis, treatment and outcome of newborns with ... Recently, advances in laboratory technology with tandem mass spectrometry (MS/MS) has increased the identification of newborns ... will explore MS/MS to provide a better understanding of the development and application of this technology to newborn screening ...
New research indicates that using waist-to-height ratio is a more accurate way of screening young children for excess stomach ... Screening using Body Mass Index alone may miss every second preschooler with excess stomach fat New research indicates that ... BMI is a screening tool that combines a persons weight and height. It has been criticized for not adequately screening people ... Reference: Lindholm, A. et al (2018). Body mass index classification misses to identify children with an elevated waist-to- ...
... screening, and characterization stations. The invention also relates to a variety of methods for synthesis, screening, and ... The wells of the array may comprise a membrane, which is used in various screening and characterization methods. The invention ... In a preferred embodiment, the synthesis, screening, and/or characterization steps are carried out in a highly parallel fashion ... The invention relates to an array, which permits various high-throughput methods for synthesis, screening and/or ...
Opportunities to Improve Airport Passenger Screening with Mass Spectrometry by the National Research Council for free. ... Opportunities to Improve Airport Passenger Screening with Mass Spectrometry (2004) Consensus Study Report ... Opportunities to Improve Airport Passenger Screening with Mass Spectrometry. (2004) Consensus Study Report ... Opportunities to Improve Airport Passenger Screening with Mass Spectrometry. Washington, DC: The National Academies Press.https ...
Screening: wann ist es angebracht und wie geht es richtig?  Weltgesundheitsorganisation. Regionalbüro für Europa; Europäischen ... Screening: when is it appropriate and how can we get it right?  ...
... the Forensic Toxicology Application Screening Solution with UNIFI1 was applied to a selection of plant alkaloids.. ... For screening, accurate mass instrumentation presents a significant, and key, advantage over its nominal mass counterpart, i.e ... Analysis of Plant Alkaloids Through Accurate Mass Screening and Discovery. Analysis of Plant Alkaloids Through Accurate Mass ... Accurate mass imparts high specificity for substance identification and, together with the isotopic data, can provide the user ...
MA. Lung Cancer Alliance provides support to lung cancer patients, caregivers, screening professionals and families. ... Find information on Mercy Medical Screening Center in Springfield, ...
  • We provide fully assisted Mass Spectrometry services at highly competitive rates. (
  • Our Mass Spectrometry facilities are world-leading and state of the art, and we are ready to assist you by providing a comprehensive screening service that will help you acheive your research goals. (
  • Don't hesitate to contact us for more information on our Mass Spectrometry screening services - please get in touch with Mass Spectrometry Facility Manager Dr Wendy Loa or GRIDD Strategic Development Manager Dr Raya Monteiro with your inquiry. (
  • These high-resolution electrospray ionisation mass spectrometry instruments support a range of research projects focused on the study of proteins and complexes of protein with fragments, compounds and natural product extracts, known as bioaffinity mass spectrometry. (
  • Our researchers have extensive expertise in applying high resolution mass spectrometry to identify new binding ligands to target proteins for drug discovery. (
  • GRIDD's Mass Spectrometry screening helped me discover a "hidden gem" in a fragment-based drug discovery research campaign. (
  • This finding provides credence for the relatively untapped opportunity to apply native state mass spectrometry as a complementary fragment screening method to accelerate drug discovery. (
  • Increasingly, tandem mass spectrometry (MS/MS) is being used for newborn screening because this laboratory testing technology substantially increases the number of metabolic disorders that can be detected from dried blood-spot specimens. (
  • The introduction of tandem mass spectrometry (MS/MS) in the 1990s for population-based newborn screening has enabled health-care providers to detect an increased number of metabolic disorders in a single process by using dried blood-spot specimens routinely collected from newborns ( 13 ). (
  • This high growth can be attributed to time-effectiveness and cost effectiveness provided by mass spectrometry as compared to the enzyme assays and immunoassays technology. (
  • TY - JOUR T1 - Rapid screening for taxanes by tandem mass spectrometry. (
  • Multiplex PCR/mass spectrometry screening of biological carcinogenic agents in human mammary tumors. (
  • A method for screening newborns using electrospray tandem mass spectrometry. (
  • The method improves the current protocols that use tandem mass spectrometry by assuring accurate and consistent results at the clinical level through enhanced quality controls and quality assurance protocols as applied to the. (
  • The method improves the current protocols that use tandem mass spectrometry by assuring accurate and consistent results at the clinical level through enhanced quality controls and quality assurance protocols as applied to the scan profiling and sample preparation of blood spots from newborns. (
  • Tandem mass spectrometry in newborn screening: a primer for neonatal and perinatal nurses. (
  • Recently, advances in laboratory technology with tandem mass spectrometry (MS/MS) has increased the identification of newborns with an EM. (
  • This is the first of that series and presents an assessment of mass spectrometry for enhanced trace detection (ETD) of chemicals contained in explosives. (
  • It then presents a discussion of the potential for mass spectrometry to improve EDT including challenges faced by such a system, recommendations for starting a program to take advantage of mass spectrometry, and recommendations for a phased implementation plan. (
  • Over the last decade there has been a significant increase in the popularity of time-of-flight mass spectrometry (Tof-MS) for multi-residue analysis. (
  • Desorption electrospray ionization (DESI) mass spectrometry (MS) is applied in a continuous on-line process at rates that approach 10 4 reactions per h at area densities of up to 1 spot per mm 2 (6144 spots per standard microtiter plate) with the sprayer moving at ca. 10 4 microns per s. (
  • A new and fully automated newborn screening method for mass spectrometry was introduced in this paper. (
  • Gaugler S, Rykl J, Wegner I, von Däniken T, Fingerhut R, Schlotterbeck G. Extended and Fully Automated Newborn Screening Method for Mass Spectrometry Detection. (
  • Visit SLAS Discovery OnlineFirst at to read Nanofractionation Platform with Parallel Mass Spectrometry for Identification of Cytochrome CYP1A2 Inhibitors in Metabolic Mixtures for free. (
  • This method, coupled to liquid chromatography-high-resolution mass spectrometry, is effective in the study of grape metabolomics, in particular for characterization of flavonols, stilbene derivatives, and anthocyanins. (
  • Riccardo Flamini, Mirko De Rosso, and Luigi Bavaresco, "Study of Grape Polyphenols by Liquid Chromatography-High-Resolution Mass Spectrometry (UHPLC/QTOF) and Suspect Screening Analysis," Journal of Analytical Methods in Chemistry , vol. 2015, Article ID 350259, 10 pages, 2015. (
  • Non-targeted screening with high-resolution accurate-mass mass spectrometry (HRAM MS) can detect a mammoth number of organic compounds without having standards. (
  • Herein we have combined an underutilized fragment screening method, native state mass spectrometry, together with two proven and popular fragment screening methods, surface plasmon resonance and X-ray crystallography, in a fragment screening campaign against human carbonic anhydrase II (CA II). (
  • Our findings demonstrate that there is a tremendous opportunity to apply native state mass spectrometry as a complementary fragment screening method to accelerate drug discovery. (
  • Fetterolf and Yost (1984) determined the informing power of various tandem mass spectrometry configurations, incuding GC/QMS, QMS/QMS, GC/QMS/QMS (see Table 2-1 ). (
  • Liquid chromatography/ultraviolet (LC/UV) and mass spectrometry/mass spectrometry (MS/MS) libraries containing 39 phenolic compounds were established by coupling a LC and an ion trap MS with an electrospray ionization (ESI) source, operated in negative ion mode. (
  • Sun J, Liang F, Bin Y, Li P, Duan C. Screening Non-colored Phenolics in Red Wines using Liquid Chromatography/Ultraviolet and Mass Spectrometry/Mass Spectrometry Libraries. (
  • Typically, the key to diagnosis is the excessive amount of malonic acid in the patient's urine, which can be detected by gas chromatography-mass spectrometry. (
  • In the study reported here, we systematically investigated the concentration of malonylcarnitine in the blood of MCD-deficient patients by electrospray ionization tandem mass spectrometry (ESI-MS/MS). Because MCD deficiency may be amenable to dietary and medical treatment, we also evaluated whether an increase in blood malonylcarnitine is detectable in the neonatal period, which would be mandatory for early presymptomatic diagnosis. (
  • Lifeline Screening Offers several different types of Health Screenings. (
  • Take a look below at all the Life Line Health Screenings offered. (
  • Quincy Medical Center hosts a variety of health screenings, educational programs and support groups throughout the year, which are open to all members of the community. (
  • Sincerity focuses on human rights activist Malcolm X. The festival will include film screenings and discussions with many of the filmmakers. (
  • Attend film screenings and events within Bristol's vibrant film and TV sector, such as the Watershed Cinema and Encounters Film Festival. (
  • Starting in 2018, the Screening Clinic will be held on the 3rd Wednesdays of the month, at the same time and location. (
  • According to a new report by Japan's Nikkan Kogyo Shimbun , screen maker Japan Display plans to start producing OLED displays for Apple's iPhone in Spring of 2018. (
  • While 2018 does seem quite a distance away, KGI Securities analyst Ming-Chi Kuo has already suggested that we may have to wait a full three years before we see an OLED screen in an iPhone while the aforementioned report by The Korea Times too quotes a 2018 target in partnership with Samsung or LG. (
  • On 16 April 2020, a COVID-19 mass screening program was initiated in Saudi Arabia in multiple phases. (
  • A retrospective cross-sectional study was conducted among the high-risk population as part of the COVID-19 mass screening program across all regions in Saudi Arabia during April and May 2020. (
  • Indonesian medical staff take part in a mass test for the COVID-19 coronavirus at Patriot stadium in Bekasi, West Java on March 25, 2020. (
  • Limpopo Provincial health official gives a thumbs up after conducting a screening test on a traveller carrying a baby while making her way from Gauteng to Limpopo ahead of the nationwide lockdown at Mantsole Weighbridge near Hammanskraal on March 25, 2020. (
  • Newborn screening is a test in which the newborns are screened for a panel of inborn diseases that can lead to disabilities or even death. (
  • Since 1961, newborn screening for errors of metabolism (EM) has improved the diagnosis, treatment and outcome of newborns with an EM. (
  • WASHINGTON - A new type of coronavirus test offers a cheaper, quicker way to screen for infections, moving the U.S. toward the kind of mass screening that experts say is essential to returning millions of Americans to school and work. (
  • Tagged as antibody test kit , coronavirus pandemic , covid19 pandemic , mass medical testing kit , mass screening test , medical tool . (
  • Ontario is not in the process of developing a mass screening technique to detect the B.1.617 coronavirus variant currently devastating India and already present in the province because global authorities have not yet deemed it a variant of concern. (
  • In June 2000, the National Newborn Screening and Genetics Resource Center, in collaboration with CDC and the Health Resources and Services Administration, convened a workshop in San Antonio, Texas. (
  • Workshop participants examined programmatic concerns for health providers choosing to integrate MS/MS technology into their newborn screening activities. (
  • This work group report contains proposals for planning, operating, and evaluating MS/MS technology in newborn screening and maternal and child health programs. (
  • As a supplement to these proposals, this report contains synopses of selected presentations made at the 2000 workshop regarding integration of MS/MS technology into newborn screening programs. (
  • The proposals contained in this report should assist policymakers, program managers, and laboratorians in making informed decisions regarding the process of including MS/MS technology in their newborn screening and maternal and child health programs. (
  • Each year, approximately 4 million babies in the United States have dried blood spots analyzed through newborn* screening programs. (
  • These three groups of disorders account for approximately 3,000 new cases of potentially fatal or debilitating disease each year for which outcomes are improved with early identification and treatment through newborn screening systems. (
  • However, using MS/MS in newborn screening programs is new, and scientific data are limited regarding incorporating this technology into newborn screening and maternal and child health programs. (
  • DUBLIN , July 17, 2014 /PRNewswire/ -- Research and Markets has announced the addition of the 'NewBorn Screening Market by Test Type, Technology, Instrument, Accessories, Reagent & Assay Kit - Global Forecast to 2019' report to their offering. (
  • This report studies the newborn screening market by test type, technology, product, and geography. (
  • The global newborn screening market, estimated at $438.9 million in 2013, is expected to reach $819.6 million by 2019, growing at a CAGR of 11.0% from 2013 to 2019. (
  • Based on types, the newborn screening market is segmented into dry blood spot test, hearing screen test, and pulse oximetry test. (
  • The newborn screening products market includes instruments, reagents, and assay kits. (
  • The high share of the instruments market can be attributed to the wide usage of newborn screening devices across the globe. (
  • This review will explore MS/MS to provide a better understanding of the development and application of this technology to newborn screening for perinatal and neonatal nurses. (
  • to develop a comprehensive biochemical assay for detection of Pompe disease (glycogen storage disease type II), to be implemented in the Newborn screening program among the Israeli population. (
  • We assessed whether population-based mass screening with a spiral computed tomography scanner could contribute substantially to detection of smaller cancers, and decrease mortality. (
  • The aim of this study was to evaluate the usefulness of annual screening for lung cancer by low-dose computed tomography (CT) and the characteristics of identified lung cancers. (
  • We considered the innovative immunological FOBT and computed tomography colonography (CTC) as competing screening technologies. (
  • Cost-effectiveness of colorectal cancer screening with computed tomography colonography according to a polyp size threshold for polypectomy ," Post-Print halshs-00480583, HAL. (
  • Radical anions of the taxanes are formed by desorption chemical ionization, and a parent tandem mass spectrometric scan is used to recognize these compounds by their characteristic dissociations. (
  • The methodology is centered around an at-line nanofractionation platform in which a metabolic mixture is chromatographically separated followed by parallel on-line mass spectrometric (MS) analysis and at-line nanofractionation on high-density microtiter well plates that are then directly exposed to a bioassay. (
  • In combination with on-line mass spectrometric (MS) analysis, it constitutes a rapid screening tool to select reagents to generate specific products. (
  • Tandem mass spectrometric determination of malonylcarnitine: diagnosis and neonatal screening of malonyl-CoA decarboxylase deficiency. (
  • Hyderabad, Aug 2 : Hyderabad's Rajiv Gandhi International Airport (RGIA) has received a UNICEF-funded a mass fever screening system to further enhance the efficacy of screening of passengers in view of COVID-19 pandemic, the airport operator announced on Sunday. (
  • Rapid testing continues to be one of our most important tools for fighting this pandemic, and the ability to perform mass screening allows us to expand testing and reach more people in more places," President and CEO Robert Ford said in a statement . (
  • Mass testing, combined with speedy isolation of cases and contact tracing, really helps to control the spread of virus during a pandemic. (
  • Students will avail of specialised tuition in the areas of film and screen media and digital filmmaking, and may also opt to get involved in voluntary work for cultural projects and film festivals, such as the Fastnet Film Festival, Schull, offered during the programme year. (
  • The MA in Film and Screen Media programme reflects the broad spectrum of research profiles and interests of our staff and is designed to provide our students with advanced knowledge of the history, theory, and aesthetics of international film and the emerging field of screen media. (
  • With its combination of theory and practice , as well as its interface with the Industry, the MA offers students a programme of study that is simultaneously extensive, eclectic and in-depth. (
  • The unique "stream" approach and range of learning methods of the MA means that students have greater flexibility in shaping the kind of programme they want, and can pursue their interests in theoretical and cultural studies, creative practice, critical writing, or the culture industry. (
  • As part of the Performance programme at Central Saint Martins, it offers the opportunity to collaborate with other courses and is delivered in close collaboration with MA Screen: Directing. (
  • MA Screen: Acting breaks away from the traditional stage-focused training by providing a specific programme directly relevant to film and television. (
  • Delivered in close working partnership with MA Screen: Directing, it features an extended programme of acting skills, two film projects which are professionally produced and shot on location and in CSM's film Studio and then edited and screened. (
  • 9 Several current guidelines recommend breast cancer screening with mammography for women aged up to 75 years, 10 11 and in the Netherlands in 1998, the upper age limit of the mass screening programme was extended from 69 to 75 years. (
  • Asymptomatic breast cancer in non-participants of the national screening programme in Norway: a confounding factor in evaluation? (
  • To evaluate the extent and histopathological characteristics of asymptomatic breast cancer detected outside the Norwegian Breast Cancer Screening Program (NBCSP) in women targeted by the programme. (
  • MS/MS technology enables improvements in and consolidation of metabolic screening methods to detect amino acid disorders (e.g. (
  • Workstation, apparatuses and methods for the high-throughput synthesis, screening and/or characterization of combinatorial libraries. (
  • The invention relates to an array, which permits various high-throughput methods for synthesis, screening and/or characterization in the same array, without requiring. (
  • The wells of the array may comprise a membrane, which is used in various screening and characterization methods. (
  • The invention also relates to a variety of methods for synthesis, screening, and characterization, which are adapted for combinatorial chemistry. (
  • This process can be improved by implementing new screening methods that rapidly assess the biological/biochemical properties and correlate them directly to compound identities. (
  • Background: Because early squamous cell carcinoma (SCC) of the esophagus is detectable by endoscopic esophageal iodine staining with high accuracy and is easily treated by endoscopic mucosectomy, it is important to develop efficient methods for screening candidates for the endoscopic examination. (
  • A successful preparative ES pathway for the synthesis of the phenylacetyl ester intermediate, using tropine/HCl/phenylacetyl chloride, was optimized for solvent in both the preparative ES and microfluidics flow systems and a base screening was conducted by both methods to increase atropine yield, increase percentage conversion and reduce byproducts. (
  • Advanced protein analysis including native protein analysis, quantification of protein/ ligand binding affinity, high throughput bioaffinity screening MS/MS analysis. (
  • Advanced protein analysis which includes native protein analysis, high throughput bioaffinity screening. (
  • Therefore, a high throughput screening technology was developed. (
  • Millions of potential interactions in several organisms have been screened in the latest decade using high-throughput screening systems (often using robots) and over thousands of interactions have been detected and categorized in databases as BioGRID. (
  • The second high-throughput approach is the library screening approach. (
  • MS/MS technology expands the metabolic disorder screening panel (i.e., the number of disorders that can be detected) by incorporating an acylcarnitine profile, which enables detection of fatty acid oxidation disorders (e.g., medium-chain acyl-CoA dehydrogenase [MCAD] deficiency) ( 7-10 ) and other organic acid disorders. (
  • The limit of detection of the individual taxanes in typical plant matrices is less than 500 pg when all three species are screened simultaneously. (
  • Oasis HLB SPE extraction with rapid ACQUITY UPLC separation and detection by Xevo G2 QTof, followed by data processing using POSI±IVE Software, were successfully used to screen extracted sewage effluent for pesticide contaminants at ultra-trace levels. (
  • The lung-cancer detection rate with CT was 0.48%, significantly higher than the 0.03-0.05% for standard mass assessments done previously in the same area. (
  • CT was more accurate in mass screening for lung cancer and led to early detection and an accurate diagnosis of lung cancer, and should be considered in future health plans. (
  • Based on our experience, launching mass screening programs is crucial for early case detection, isolation, and pattern recognition for immediate public interventions. (
  • Repeat CT allowed the detection of more aggressive, rapidly growing lung cancers, compared to those in the initial screening. (
  • Twenty percent (19/97) of the ICs and 32% (69/213) of the breast cancers in non-participants were asymptomatic, with opportunistic screening as the most frequent detection method (42%, 8/19 for ICs and 54%, 37/69 for non-participants). (
  • There'll be opportunities to network with other future creative leaders, working alongside students on our other postgraduate screen courses. (
  • With a strong emphasis on practice and production-based work running through the course, you'll learn about the industrial and business context of film and TV, and build valuable enterprise skills, working with students on our other postgraduate screen MAs. (
  • In 1996, we screened in a mobile unit 5483 individuals from the general population of Matsumoto, Japan, aged between 40 years and 74 years who had undergone annual chest radiography (miniature fluorophotography) and cytological assessment of sputum. (
  • The initial screening in 1996 detected suspicious nodules in 279 (5.1%) of 5483 subjects, and 22 (8%) were confirmed surgically to have lung cancer. (
  • The sensitivity and specificity of detecting surgically confirmed lung cancer were 55% (22/40) and 95% (4960/5199) in 1996 and 83% (25/30) and 97% (4113/4252) in 1997 screening, respectively. (
  • Results: When individuals ranked in the top 10% of the HRA-F risk score was screened, the sensitivity was 57.9% and positive predictive value was 0.93% or 2.12% according to the above assumptions, respectively. (
  • The tandem mass spectroscopy market is expected to witness the highest growth. (
  • Included in this endeavor is TSA's Certified Cargo Screening Program (CCSP), which enables Indirect Air Carriers (IAC's), shippers, and Independent Cargo Screening Facilities (ICSF's) to screen cargo for flights originating in the U.S. According to TSA, most shippers involved in CCSP have readily incorporated physical search into their packing/shipping operation at minimal cost without needing to invest in screening equipment. (
  • The screening tool enables users to complete a preliminary evaluation of hydropower generation potential at water supply and waste water treatment facilities. (
  • The stability of mass measurement on the Xevo G2 QTof enables a reduction in processing errors along with minimized false positives. (
  • TreePad's 'mass node mover' screen enables you to swiftly perform multiple tree operations in one go. (
  • Health screening enables you to find out if you have a particular disease or condition even if you do not have any symptoms and/or signs of disease. (
  • Prototype application integrating dashboard chemical content with Competitive Fragmentation Modeling for Metabolite Identification (CFM-ID) fragment prediction results enables screening 875,000 plus "MS Ready" compounds in complex samples - available only inside EPA at present and will be integrated to the CompTox Chemicals Dashboard in the future. (
  • An easy default in these situations is to turn on the TV or let them play on a tablet, though the American Academy of Pediatrics highly recommends restricting screen time for children, especially when they're young. (
  • Firefighters filled Sullivan Auditorium at Worcester State University last night for a special screening of the documentary with the executive producer, Denis Leary, a Worcester native. (
  • One of the featured documentaries is Finding Lights of Hope, which focuses on youth activism in Worcester, and this year s Central Mass Film Festival is sure to focus a lens on the local stars of social activism. (
  • It is free, but donations are being accepted to benefit the Central Mass Film Festival and Worcester Roots Project, a collective of youth and adult organizers on a mission to create opportunities for economic, social and environmental justice. (
  • Laboratory diagnosis of and subsequently retesting single specimens from SARS-CoV-2 infection was performed with all speci- positive pools is an efficient strategy for rapid mass mens using the following rRT-PCR kits targeting the E screening as well as for increasing testing capacity and RdRp genes: STANDARD M nCoV Real-time and conserving resources. (
  • 8 It has been assumed that diagnosis at an earlier stage through screening programmes could improve the prognosis of breast cancer and may therefore be beneficial for older women. (
  • To compute a ratio between the estimated numbers of lives saved from breast cancer death and the number of women diagnosed with a breast cancer that never would have been diagnosed during the woman's lifetime had she not attended screening (epidemiologic over-diagnosis) in the Norwegian Breast Cancer Screening Program. (
  • The benefit-detriment ratio estimates of the Norwegian Breast Cancer Screening Program, expressed as lives saved from breast cancer death and epidemiologic over-diagnosis, should be interpreted with care due to substantial uncertainties in the estimates, and the differences in the scale of values of the events compared. (
  • We reviewed medical records of the 83 patients and determined the intervals from the mass-screening to the pathological diagnosis with clinical staging. (
  • Kanashiki M, Satoh H, Ishikawa H, Yamashita YT, Ohtsuka M and Sekizawa K: Time from finding abnormality on mass-screening to final diagnosis of lung cancer. (
  • A COVID-19 protein arrived the laboratory in the morning of 30 April, the screen development completed that afternoon and we are now ready to screen for antiviral compounds. (
  • Alden Research Laboratory, Inc. working on behalf of the Massachusetts Department of Environmental Protection (MassDEP) and the Massachusetts Clean Energy Center (MassCEC) developed a screening tool for in-conduit (inside the pipe or channel) hydropower technologies with a focus on water infrastructure opportunities managed by municipalities or districts. (
  • Antigen tests on the whole are not as accurate as molecular-based PCR tests, but that accuracy comes with trade-offs-such as the need for centralized laboratory equipment and potentially days to turn around a result-which may delay a person from safely isolating themselves or make it a poorer option for mass screening. (
  • If precancerous polyps in the colon or rectum are found and removed during a screening colonoscopy, many cancers can be prevented. (
  • 88% (55/60) of lung cancers identified on screening and surgically confirmed were AJCC stage IA. (
  • The cancers were divided into screening-detected cancers in the NBCSP, interval cancers (ICs) and cancers detected in women not participating in the NBCSP (never participated and lapsed attendees), and further into asymptomatic and symptomatic cancers. (
  • There were no differences in distribution of NPI prognostic categories across subgroups of asymptomatic invasive cancers (screening-detected cancers in the NBCSP, asymptomatic ICs and asymptomatic cancers in non-participants) or between subgroups of symptomatic invasive cancers (symptomatic ICs and symptomatic cancers in non-participants). (
  • Screening of environmental waters is especially important because the use of pesticides and similar compounds has steadily increased in an effort to meet global food demands. (
  • Suspect screening analysis is a targeted metabolomics method in which the identification of compounds relies on specific available information, such as their molecular formula and isotopic pattern. (
  • Non-Target Screening Using LC/Q-TOF MS and the EPA CompTox Chemical Dashboard is looking to detect compounds in water. (
  • A further 70 compounds that comprised the initial hit chemotypes were subsequently sourced from the full CSIRO compound collection and screened. (
  • This screening is intended to detect inborn disorders that can result in early mortality or lifelong disability. (
  • Many companies are working on versions that would be more accurate, easier to use and more suitable for mass screenings. (
  • Find out which recommended health screening test is suitable for you. (
  • Inactive aldehyde dehydrogenase-2 (ALDH2) is a very strong risk factor for esophageal SCC in alcohol drinkers and thus may be suitable as a screening tool. (
  • however, this relies on the acquired exact mass for each compound remaining very precise across the entire peak for that compound. (
  • In a preferred embodiment, the synthesis, screening, and/or characterization steps are carried out in a highly parallel fashion, where more than one compound is synthesized, screened, and/or characterized at the same time. (
  • The Fort Sill CID Office received an intelligence bulletin regarding a credible potential mass shooting to occur at an unknown movie theater during the release of the new Joker movie scheduled on October 4, 2019," the memo reads. (
  • Objective Fluctuations in the incidence of breast cancer in Norway in the last three decades are partly explained by the use of hormone replacement therapy and mammography screening, but overdiagnosis has also been suggested as a cause. (
  • A low-dose CT scan (LDCT) is the only screening test for lung cancer recommended by the US Preventive Services Task Force. (
  • Use these frequently asked questions (FAQ) to learn more about lung cancer screening and access resources to help support patients. (
  • Who should be screened for lung cancer? (
  • Referrals to the Mass General Lung Screening and Pulmonary Nodule Clinic can be made by emailing [email protected] or via CRMS (for clinicians within Partners). (
  • Mass-screening for lung cancer is rather a unique system in Japan. (
  • Among the 517 patients with lung cancer who were admitted to our hospital over a 10-year period up to December 2001, 83 (16.1%) were detected by mass-screening. (
  • The Norwegian Breast Cancer Screening Program invites women aged 50-69 to biennial mammographic screening. (
  • Researchers at Massachusetts General Hospital's (MGH) Ammon-Pinizzotto Center for Women's Mental Health have developed the MGH Perinatal Depression Scale (MGHPDS) , a free iPhone application designed to refine how women around the world are screened for postpartum depression (PPD). (
  • The MGHPDS app blends together digital versions of perinatal depression screening tools such as the Edinburgh Postpartum Depression Scale, a 10-question self-rating scale which is the most common tool for identifying women at risk for PPD, with other instruments that measure symptoms associated with perinatal psychiatric illness - such as sleep disturbance, anxiety and perceived stress. (
  • It is our hope that - as screening for PPD becomes increasingly common across the U.S. and globally - easy-to-use tools like the MGHPDS, which can be readily used on smartphones and other digital devices, will lead to more accurate screening of perinatal mood and anxiety disorders and to improved clinical outcomes for patients. (
  • News of these notices comes just a day after the Aurora Police Department in Colorado let residents know that the Century Aurora and XD movie theater, which was the site of a mass shooting in July 2012, will not be showing "Joker. (
  • LG ( 066570 ) announced on Thursday that it has started firing up its production lines to produce screens for the next-generation iPhone , and it looks as though the new screens will indeed be longer and thinner than previous iPhone models. (
  • Unnamed sources told Reuters on Thursday that the new LG -produced iPhone screens will measure four inches corner-to-corner , or one half-inch longer than current iPhone screens, They are also thinner and include new technology that "embeds touch sensors into the liquid crystal display, eliminating the touch-screen layer found in current iPhones. (
  • That jives with recent speculation that the iPhone will not see an OLED screen for the next three or so years. (
  • Japan Display, a joint venture formed by Hitachi, Toshiba and Sony in 2012 is already supplying LCD iPhone screens for Apple, and its executives are reportedly already in discussions with the iPhone maker with an eye on a future deal. (
  • Based on Apple's current release cadence and with the iPhone 7 due in September next year, the iPhone 8 appears to be the handset earmarked for that fabled OLED screen. (
  • In an initial fragment screen against a 720-member fragment library (the "CSIRO Fragment Library") seven CA II binding fragments, including a selection of nonclassical CA II binding chemotypes, were identified. (
  • For screening, accurate mass instrumentation presents a significant, and key, advantage over its nominal mass counterpart, i.e., an ability to implement screening methodologies without the requirement of reference material. (
  • Audio work related to screen based content can range from voice over for advertising, automated dialogue replacement and voicing characters for animation. (
  • The first City of Cambridge/Community Legal Services and Counseling Center (CLSACC) Immigration Legal Screening Clinic will be held on Wednesday, Dec.13, from 5:15-7:15 p.m., at the offices of Community Legal Services and Counseling Center (CLSACC), 47 Thorndike St (lower level) in East Cambridge. (
  • If you would like to continue helping us improve, join our user panel to test new features for the site. (
  • The test from Quidel Corp. screens for new infections but in a different way. (
  • The new test uses a nasal swab like other screening tests, and delivers results in about 15 minutes. (
  • If everyone aged 50 or older had a screening test, as many as 90 percent of deaths from colorectal cancer could be prevented. (
  • A mass screening test for COVID-19 is urgently and 300 individual SARS-CoV-2-negative specimens. (
  • Abbott has received new COVID-19 diagnostic approvals in Europe for its rapid Panbio antigen test, clearing it for self-performed screening under supervision as well as widespread use by people who have not shown symptoms of the disease. (
  • A simple finger-stick test used to assess how well your kidneys are functioning, a creatinine screening uses an FDA-approved device adopted by more than 250 hospitals nationwide. (
  • A simple finger-stick screening that measures CRP levels in your blood, this test can help determine heart disease and stroke risk levels. (
  • The test is most commonly used to screen for drug use. (
  • You might also need a urine test to screen for amphetamine or a blood test to check for other drugs such as marijuana and cocaine. (
  • is a concept home antibody test kit that offers a new way of mass screening tests, everyone can do it at the comfort of their home. (
  • Instead of developing a PCR-based screen for B.1.617, Public Health Ontario says it is instead running five per cent of samples that test negative for the specific spike protein mutation found in the UK and South African variants through whole genomic sequencing, with help coming from the National Microbiology lab in Winnipeg. (
  • Our MA prepares you for a career in subtitling or translating. (
  • MA Screen: Acting prepares you for work in film and television and related fields by bringing together the key artistic knowledge and skills that are needed to give a truthful and exciting performance on screen. (
  • You will work closely with MA Screen: Directing students on camera-based projects throughout the course. (
  • MA Screen: Acting is delivered in close collaboration with MA Screen: Directing. (
  • MA Screenwriting students work alongside MA Film students studying directing, producing, editing, cinematography and sound. (
  • Waters Xevo G2 QTof MS coupled with ACQUITY UPLC, along with the Waters ToF Screening Pesticide Database, and POSI±IVE Software processing, were used to rapidly screen treated sewage effluent that had been extracted using Oasis HLB SPE Cartridges. (
  • Figure 2 shows the effect of using increasingly narrow mass extraction windows when reviewing Xevo G2 QTof MS data. (
  • Objective To assess the incidence of early stage and advanced stage breast cancer before and after the implementation of mass screening in women aged 70-75 years in the Netherlands in 1998. (
  • Corresponding figures in 1997 and 1998 screening studies were 173 (3.9%) of 4425 and 25 (14%) of 173, and 136 (3.5%) of 3878 and 9 (7%) of 136, respectively. (
  • In yeast two-hybrid screening, separate bait and prey plasmids are simultaneously introduced into the mutant yeast strain or a mating strategy is used to get both plasmids in one host cell. (
  • A Drama Centre course at Central Saint Martins, MA Screen: Acting provides a rigorous conservatoire training, focused on performance for the screen. (
  • We proposed to apply them to the assessment of mass screening of colorectal cancer. (
  • They can be used to screen healthy individuals to predict predisposition to disease or to detect the presence of asymptomatic disease ( e.g. prostate-specific antigen for prostate cancer). (
  • A non-invasive procedure used to detect irregular heartbeat (a major risk factor for stroke), an Atrial Fibrillation screening is performed by attaching EKG electrodes above your wrists and ankles. (
  • Ontario has a rigorous and widespread screening program to detect the B.1.1.7 variant first discovered in the UK, the P.1 variant first found in Brazil and the B.1.353 variant first discovered in South Africa, with a majority of all positive samples run through screening to determine their likely lineage. (
  • An educational program aimed at reducing coronary risk factors was offered to the first 1,250 persons screened. (
  • The prevalence of 0, 1, 2, 3, 4, 5, or 6 coronary risk factors did not change significantly between the two screens in either the total group of 1,817 adults or in the 872 adults in the educational program. (
  • The Long Beach Heart Association mass screening program for coronary risk factors was ineffective in reducing the number of coronary risk factors. (
  • Disorders not identifiable by blood screening are detectable by this program. (
  • Balancing the benefits and detriments among women targeted by the Norwegian Breast Cancer Screening Program. (
  • Nowak shares her story to stress the importance of colorectal screenings. (
  • Incremental net benefit and acceptability of alternative health policies: a case study of mass screening for colorectal cancer ," Post-Print halshs-00656826, HAL. (
  • Incremental net benefit and acceptability of alternative health policies: a case study of mass screening for colorectal cancer ," The European Journal of Health Economics , Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 13(3), pages 237-250, June. (
  • Colorectal cancer in Italy: a review of current national and regional practice on screening and treatment ," The European Journal of Health Economics , Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 10(1), pages 41-49, January. (
  • The CMF2 Planning Committee has "learned a lot" by planning the screenings, Wells acknowledged. (
  • The work of Bangor University Film MA graduate, Charlotte Wells, will be amongst the documentaries screened when the third Wales International Documentary Festival returns to Blackwood this week. (
  • 100 μs when reaction acceleration occurs in microdroplets, enabling the rapid screening of processes like N -alkylation and Suzuki coupling reactions as reported herein. (
  • The rapid growth of mHealth in psychiatry has led to the development of a variety of web-driven screening tools for many mental health issues, yet to date there has been little attention to the use of technology to better diagnose and treat PPD," says Lee S. Cohen, MD, director of the Ammon-Pinizzotto Center and professor of Psychiatry at Harvard Medical School. (
  • This screening method incorporates a person's waist circumference together with his or her height. (
  • Therefore, if only the BMI is used as a screening method, children who might need further investigation for cardiometabolic risk factors could be missed despite having an elevated waist-to-height ratio. (
  • therefore, a more effective screening method is required. (
  • Regardless of the source, they are subsequently incorporated into the protein-encoding sequence of a plasmid, which is then transfected into the cells chosen for the screening method. (
  • MA Screen Acting course specialises in giving the actor a rigorous and intense conservatoire training focused on delivering performance for the screen. (
  • Apple has used LCD screens in its iPhones since day one, but OLED displays are capable of darker blacks and improved contrast while also using less power. (
  • The brother of figure skater Nancy Kerrigan was sent to jail Monday after failing required alcohol screenings while awaiting trial on manslaughter charges in the death of his father. (
  • The readings, which ranged from .025 to .036, were below the legal driving limit of .08, but violate the conditions of Kerrigan s bail, which included that he not drink alcohol and that he be given random drug and alcohol screenings. (
  • A possible approach to mass screening of high-risk individuals is to classify them according to exposure to risk factors such as heavy alcohol drinking and smoking. (
  • Screening of filter paper urine specimens for metabolic and transport disorders has been conducted in Massachusetts for the past few years. (
  • Building on our links with festivals, studios, cinemas and galleries, this MA is not only about studying film theory but also about immersing yourself in the wealth of screen-related events and institutions the capital has to offer. (
  • In addition, Screen Academy students can buy an Industry Pass at a heavily-discounted rate and to attend screenings, masterclasses and networking events at the Edinburgh International Film Festival in June. (
  • Here we present a new technology, accurate inclusion mass screening (AIMS), designed to provide a bridge from unbiased discovery to MS-based targeted assay development. (
  • Accurate inclusion mass screening: a bridge from unbiased discovery to targeted assay development for biomarker verification. (
  • The most common screening approach is the yeast two-hybrid assay. (
  • MA Screen: Acting originates from the unique approach and techniques developed by Drama Centre. (
  • MA Screen: Acting provides training for screen actors interested in character-led storytelling. (
  • MA Screen: Acting teaches students the relevant skills, equipping them with the ability to respond to the needs of employers in the screen industries. (
  • Integrating individual and group work, MA Screen: Acting promotes collaborative, joined-up thinking in the creative process of screen-based fiction. (
  • On MA Screen: Acting, you will begin with classes before moving onto projects. (
  • MA Screen: Acting lasts 45 weeks over 12 months and is structured as units - class-based to begin with, but increasingly project-geared over time. (
  • Students who come to MA Screen: Acting expect vocational training plus a high level of autonomous learning. (
  • This 18-month full time (January start) MA in Screen Acting offers students professional training in acting for a range of screen based industries. (
  • With a focus on story craft and character development you will continually engage with traditional acting and devising classes as you progress a fuller understanding of screen based narratives and the demands of the numerous forms of screen acting you may be required to collaborate in. (
  • Underpinned by a company mentality and traditional visceral acting methodology classes, students will also be trained in Motion Capture Performance, Combat for the Screen and Voice for the Screen, as they gain a deep applied knowledge of the opportunities for the contemporary screen actor. (
  • MA Screen Acting will be delivered in the new £30m Tech Park at the Bognor Regis campus. (
  • Patients with a positive screening low-dose CT scan (LDCT) will need further evaluation, most commonly CT scans at shorter intervals than the one-year screening interval to assess nodule growth. (
  • Purpose: To assess the performance of health risk appraisal (HRA) models in screening for esophageal SCC in the Japanese male population. (
  • The new thermal scanner is a ceiling mounted mass fever screening system capable of scanning, detecting and tracking febrile persons with elevated skin temperature. (
  • Limestone screenings for thermal mass? (
  • Super Insulated Floors With Thermal Mass? (