Maintenance: The upkeep of property or equipment.Maintenance Chemotherapy: Treatment designed to help prevent a relapse of a disease following the successful primary treatments (INDUCTION CHEMOTHERAPY and CONSOLIDATION CHEMOTHERAPY) with a long-term low-dose drug therapy.Health Maintenance Organizations: Organized systems for providing comprehensive prepaid health care that have five basic attributes: (1) provide care in a defined geographic area; (2) provide or ensure delivery of an agreed-upon set of basic and supplemental health maintenance and treatment services; (3) provide care to a voluntarily enrolled group of persons; (4) require their enrollees to use the services of designated providers; and (5) receive reimbursement through a predetermined, fixed, periodic prepayment made by the enrollee without regard to the degree of services provided. (From Facts on File Dictionary of Health Care Management, 1988)Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)Time Factors: Elements of limited time intervals, contributing to particular results or situations.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Pregnancy Maintenance: Physiological mechanisms that sustain the state of PREGNANCY.Telomere: A terminal section of a chromosome which has a specialized structure and which is involved in chromosomal replication and stability. Its length is believed to be a few hundred base pairs.Cell Differentiation: Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.Minichromosome Maintenance Complex Component 2: A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It contains a NUCLEAR LOCALIZATION SIGNAL which may provide targeting of the protein complex and an extended N-terminus which is rich in SERINE residues.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Mice, Knockout: Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.DNA-Binding Proteins: Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.Mice, Inbred C57BLGene Expression Regulation, Developmental: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action during the developmental stages of an organism.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Models, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Stem Cells: Relatively undifferentiated cells that retain the ability to divide and proliferate throughout postnatal life to provide progenitor cells that can differentiate into specialized cells.Homeostasis: The processes whereby the internal environment of an organism tends to remain balanced and stable.Opiate Substitution Treatment: Medical treatment for opioid dependence using a substitute opiate such as METHADONE or BUPRENORPHINE.Transcription Factors: Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.Nuclear Proteins: Proteins found in the nucleus of a cell. Do not confuse with NUCLEOPROTEINS which are proteins conjugated with nucleic acids, that are not necessarily present in the nucleus.Renal Dialysis: Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Mice, Transgenic: Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.Telomerase: An essential ribonucleoprotein reverse transcriptase that adds telomeric DNA to the ends of eukaryotic CHROMOSOMES.Cell Cycle Proteins: Proteins that control the CELL DIVISION CYCLE. This family of proteins includes a wide variety of classes, including CYCLIN-DEPENDENT KINASES, mitogen-activated kinases, CYCLINS, and PHOSPHOPROTEIN PHOSPHATASES as well as their putative substrates such as chromatin-associated proteins, CYTOSKELETAL PROTEINS, and TRANSCRIPTION FACTORS.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Cell Line: Established cell cultures that have the potential to propagate indefinitely.Telomere Homeostasis: Maintenance of TELOMERE length. During DNA REPLICATION, chromosome ends loose some of their telomere sequence (TELOMERE SHORTENING.) Various cellular mechanism are involved in repairing, extending, and recapping the telomere ends.Opioid-Related Disorders: Disorders related or resulting from abuse or mis-use of opioids.DNA Replication: The process by which a DNA molecule is duplicated.Gene Expression Regulation: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.Narcotics: Agents that induce NARCOSIS. Narcotics include agents that cause somnolence or induced sleep (STUPOR); natural or synthetic derivatives of OPIUM or MORPHINE or any substance that has such effects. They are potent inducers of ANALGESIA and OPIOID-RELATED DISORDERS.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Genomic Instability: An increased tendency of the GENOME to acquire MUTATIONS when various processes involved in maintaining and replicating the genome are dysfunctional.Minichromosome Maintenance Complex Component 7: A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It is also found in tightly-bound trimeric complex with MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 4 and MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 6.Corpus Luteum Maintenance: Process of maintaining the functions of CORPORA LUTEA, specifically PROGESTERONE production which is regulated primarily by pituitary LUTEINIZING HORMONE in cycling females, and by PLACENTAL HORMONES in pregnant females. The ability to maintain luteal functions is important in PREGNANCY MAINTENANCE.Energy Metabolism: The chemical reactions involved in the production and utilization of various forms of energy in cells.Heroin Dependence: Strong dependence, both physiological and emotional, upon heroin.Recurrence: The return of a sign, symptom, or disease after a remission.Homeodomain Proteins: Proteins encoded by homeobox genes (GENES, HOMEOBOX) that exhibit structural similarity to certain prokaryotic and eukaryotic DNA-binding proteins. Homeodomain proteins are involved in the control of gene expression during morphogenesis and development (GENE EXPRESSION REGULATION, DEVELOPMENTAL).Protein Binding: The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.Drosophila Proteins: Proteins that originate from insect species belonging to the genus DROSOPHILA. The proteins from the most intensely studied species of Drosophila, DROSOPHILA MELANOGASTER, are the subject of much interest in the area of MORPHOGENESIS and development.RNA Interference: A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.Meristem: A group of plant cells that are capable of dividing infinitely and whose main function is the production of new growth at the growing tip of a root or stem. (From Concise Dictionary of Biology, 1990)Gene Deletion: A genetic rearrangement through loss of segments of DNA or RNA, bringing sequences which are normally separated into close proximity. This deletion may be detected using cytogenetic techniques and can also be inferred from the phenotype, indicating a deletion at one specific locus.Saccharomyces cerevisiae Proteins: Proteins obtained from the species SACCHAROMYCES CEREVISIAE. The function of specific proteins from this organism are the subject of intense scientific interest and have been used to derive basic understanding of the functioning similar proteins in higher eukaryotes.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Drug Administration Schedule: Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.Saccharomyces cerevisiae: A species of the genus SACCHAROMYCES, family Saccharomycetaceae, order Saccharomycetales, known as "baker's" or "brewer's" yeast. The dried form is used as a dietary supplement.Remission Induction: Therapeutic act or process that initiates a response to a complete or partial remission level.Cell Division: The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.Reverse Transcriptase Polymerase Chain Reaction: A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.Membrane Proteins: Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.Plasmids: Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.Cell Cycle: The complex series of phenomena, occurring between the end of one CELL DIVISION and the end of the next, by which cellular material is duplicated and then divided between two daughter cells. The cell cycle includes INTERPHASE, which includes G0 PHASE; G1 PHASE; S PHASE; and G2 PHASE, and CELL DIVISION PHASE.Transcription, Genetic: The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION.Chromosomal Proteins, Non-Histone: Nucleoproteins, which in contrast to HISTONES, are acid insoluble. They are involved in chromosomal functions; e.g. they bind selectively to DNA, stimulate transcription resulting in tissue-specific RNA synthesis and undergo specific changes in response to various hormones or phytomitogens.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Weight Loss: Decrease in existing BODY WEIGHT.Embryonic Stem Cells: Cells derived from the BLASTOCYST INNER CELL MASS which forms before implantation in the uterine wall. They retain the ability to divide, proliferate and provide progenitor cells that can differentiate into specialized cells.Cell Survival: The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.Neurons: The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.Histones: Small chromosomal proteins (approx 12-20 kD) possessing an open, unfolded structure and attached to the DNA in cell nuclei by ionic linkages. Classification into the various types (designated histone I, histone II, etc.) is based on the relative amounts of arginine and lysine in each.Repressor Proteins: Proteins which maintain the transcriptional quiescence of specific GENES or OPERONS. Classical repressor proteins are DNA-binding proteins that are normally bound to the OPERATOR REGION of an operon, or the ENHANCER SEQUENCES of a gene until a signal occurs that causes their release.Chromatin: The material of CHROMOSOMES. It is a complex of DNA; HISTONES; and nonhistone proteins (CHROMOSOMAL PROTEINS, NON-HISTONE) found within the nucleus of a cell.Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Blotting, Western: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.Cell Polarity: Orientation of intracellular structures especially with respect to the apical and basolateral domains of the plasma membrane. Polarized cells must direct proteins from the Golgi apparatus to the appropriate domain since tight junctions prevent proteins from diffusing between the two domains.Gene Silencing: Interruption or suppression of the expression of a gene at transcriptional or translational levels.Cell Lineage: The developmental history of specific differentiated cell types as traced back to the original STEM CELLS in the embryo.Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.DNA Damage: Injuries to DNA that introduce deviations from its normal, intact structure and which may, if left unrepaired, result in a MUTATION or a block of DNA REPLICATION. These deviations may be caused by physical or chemical agents and occur by natural or unnatural, introduced circumstances. They include the introduction of illegitimate bases during replication or by deamination or other modification of bases; the loss of a base from the DNA backbone leaving an abasic site; single-strand breaks; double strand breaks; and intrastrand (PYRIMIDINE DIMERS) or interstrand crosslinking. Damage can often be repaired (DNA REPAIR). If the damage is extensive, it can induce APOPTOSIS.Minichromosome Maintenance Complex Component 6: A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It is also found in tightly-bound trimeric complex with MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 4 and MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 7.Embryo, Mammalian: The entity of a developing mammal (MAMMALS), generally from the cleavage of a ZYGOTE to the end of embryonic differentiation of basic structures. For the human embryo, this represents the first two months of intrauterine development preceding the stages of the FETUS.Apoptosis: One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.In Situ Hybridization: A technique that localizes specific nucleic acid sequences within intact chromosomes, eukaryotic cells, or bacterial cells through the use of specific nucleic acid-labeled probes.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Double-Blind Method: A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.Drosophila: A genus of small, two-winged flies containing approximately 900 described species. These organisms are the most extensively studied of all genera from the standpoint of genetics and cytology.DNA Helicases: Proteins that catalyze the unwinding of duplex DNA during replication by binding cooperatively to single-stranded regions of DNA or to short regions of duplex DNA that are undergoing transient opening. In addition DNA helicases are DNA-dependent ATPases that harness the free energy of ATP hydrolysis to translocate DNA strands.Telomere-Binding Proteins: Proteins that specifically bind to TELOMERES. Proteins in this class include those that perform functions such as telomere capping, telomere maintenance and telomere stabilization.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Immunosuppressive Agents: Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.Protein Structure, Tertiary: The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.Carrier Proteins: Transport proteins that carry specific substances in the blood or across cell membranes.RNA, Small Interfering: Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions.Mitosis: A type of CELL NUCLEUS division by means of which the two daughter nuclei normally receive identical complements of the number of CHROMOSOMES of the somatic cells of the species.DNA (Cytosine-5-)-Methyltransferase: An enzyme that catalyzes the transfer of a methyl group from S-ADENOSYLMETHIONINE to the 5-position of CYTOSINE residues in DNA.Analysis of Variance: A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.Memory, Short-Term: Remembrance of information for a few seconds to hours.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Models, Genetic: Theoretical representations that simulate the behavior or activity of genetic processes or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.Protein Transport: The process of moving proteins from one cellular compartment (including extracellular) to another by various sorting and transport mechanisms such as gated transport, protein translocation, and vesicular transport.Green Fluorescent Proteins: Protein analogs and derivatives of the Aequorea victoria green fluorescent protein that emit light (FLUORESCENCE) when excited with ULTRAVIOLET RAYS. They are used in REPORTER GENES in doing GENETIC TECHNIQUES. Numerous mutants have been made to emit other colors or be sensitive to pH.DNA Repair: The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light.Epithelial Cells: Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.Drosophila melanogaster: A species of fruit fly much used in genetics because of the large size of its chromosomes.Hematopoietic Stem Cells: Progenitor cells from which all blood cells derive.DNA: A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).Gene Expression Profiling: The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.Flow Cytometry: Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.DNA Methylation: Addition of methyl groups to DNA. DNA methyltransferases (DNA methylases) perform this reaction using S-ADENOSYLMETHIONINE as the methyl group donor.DNA Primers: Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.Protein-Serine-Threonine Kinases: A group of enzymes that catalyzes the phosphorylation of serine or threonine residues in proteins, with ATP or other nucleotides as phosphate donors.Epigenesis, Genetic: A genetic process by which the adult organism is realized via mechanisms that lead to the restriction in the possible fates of cells, eventually leading to their differentiated state. Mechanisms involved cause heritable changes to cells without changes to DNA sequence such as DNA METHYLATION; HISTONE modification; DNA REPLICATION TIMING; NUCLEOSOME positioning; and heterochromatization which result in selective gene expression or repression.Gene Knockdown Techniques: The artificial induction of GENE SILENCING by the use of RNA INTERFERENCE to reduce the expression of a specific gene. It includes the use of DOUBLE-STRANDED RNA, such as SMALL INTERFERING RNA and RNA containing HAIRPIN LOOP SEQUENCE, and ANTI-SENSE OLIGONUCLEOTIDES.Nerve Tissue ProteinsCell Nucleus: Within a eukaryotic cell, a membrane-limited body which contains chromosomes and one or more nucleoli (CELL NUCLEOLUS). The nuclear membrane consists of a double unit-type membrane which is perforated by a number of pores; the outermost membrane is continuous with the ENDOPLASMIC RETICULUM. A cell may contain more than one nucleus. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)6-Mercaptopurine: An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Phosphorylation: The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.Stem Cell Niche: A particular zone of tissue composed of a specialized microenvironment where stem cells are retained in a undifferentiated, self-renewable state.Promoter Regions, Genetic: DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.Microscopy, Fluorescence: Microscopy of specimens stained with fluorescent dye (usually fluorescein isothiocyanate) or of naturally fluorescent materials, which emit light when exposed to ultraviolet or blue light. Immunofluorescence microscopy utilizes antibodies that are labeled with fluorescent dye.Reproduction: The total process by which organisms produce offspring. (Stedman, 25th ed)Minichromosome Maintenance Complex Component 3: A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It contains a NUCLEAR LOCALIZATION SIGNAL, which provide targeting of the protein complex. In addition, acetylation of this protein may play a role in regulating of DNA replication and cell cycle progression.Drug Therapy, Combination: Therapy with two or more separate preparations given for a combined effect.Alleles: Variant forms of the same gene, occupying the same locus on homologous CHROMOSOMES, and governing the variants in production of the same gene product.Recombination, Genetic: Production of new arrangements of DNA by various mechanisms such as assortment and segregation, CROSSING OVER; GENE CONVERSION; GENETIC TRANSFORMATION; GENETIC CONJUGATION; GENETIC TRANSDUCTION; or mixed infection of viruses.Germ Cells: The reproductive cells in multicellular organisms at various stages during GAMETOGENESIS.Arabidopsis Proteins: Proteins that originate from plants species belonging to the genus ARABIDOPSIS. The most intensely studied species of Arabidopsis, Arabidopsis thaliana, is commonly used in laboratory experiments.Recombinant Proteins: Proteins prepared by recombinant DNA technology.Animals, Genetically Modified: ANIMALS whose GENOME has been altered by GENETIC ENGINEERING, or their offspring.Trans-Activators: Diffusible gene products that act on homologous or heterologous molecules of viral or cellular DNA to regulate the expression of proteins.Fibroblasts: Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.Cell Line, Tumor: A cell line derived from cultured tumor cells.Sequence Homology, Amino Acid: The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.Buprenorphine: A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.Cattle: Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.Down-Regulation: A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.Temperature: The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.Recombinant Fusion Proteins: Recombinant proteins produced by the GENETIC TRANSLATION of fused genes formed by the combination of NUCLEIC ACID REGULATORY SEQUENCES of one or more genes with the protein coding sequences of one or more genes.Fungal Proteins: Proteins found in any species of fungus.Arabidopsis: A plant genus of the family BRASSICACEAE that contains ARABIDOPSIS PROTEINS and MADS DOMAIN PROTEINS. The species A. thaliana is used for experiments in classical plant genetics as well as molecular genetic studies in plant physiology, biochemistry, and development.Mitochondria: Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.Cell Culture Techniques: Methods for maintaining or growing CELLS in vitro.Species Specificity: The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.Transfection: The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.Zebrafish: An exotic species of the family CYPRINIDAE, originally from Asia, that has been introduced in North America. They are used in embryological studies and to study the effects of certain chemicals on development.Induction Chemotherapy: Initial drug treatment designed to bring about REMISSION INDUCTION. It is typically a short-term and high-dose drug treatment that is followed by CONSOLIDATION CHEMOTHERAPY and then MAINTENANCE CHEMOTHERAPY.Schizosaccharomyces pombe Proteins: Proteins obtained from the species Schizosaccharomyces pombe. The function of specific proteins from this organism are the subject of intense scientific interest and have been used to derive basic understanding of the functioning similar proteins in higher eukaryotes.Energy Intake: Total number of calories taken in daily whether ingested or by parenteral routes.Budesonide: A glucocorticoid used in the management of ASTHMA, the treatment of various skin disorders, and allergic RHINITIS.Heterochromatin: The portion of chromosome material that remains condensed and is transcriptionally inactive during INTERPHASE.Proteins: Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.Morphogenesis: The development of anatomical structures to create the form of a single- or multi-cell organism. Morphogenesis provides form changes of a part, parts, or the whole organism.HeLa Cells: The first continuously cultured human malignant CELL LINE, derived from the cervical carcinoma of Henrietta Lacks. These cells are used for VIRUS CULTIVATION and antitumor drug screening assays.Mice, Mutant Strains: Mice bearing mutant genes which are phenotypically expressed in the animals.Cloning, Molecular: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.Embryo, Nonmammalian: The developmental entity of a fertilized egg (ZYGOTE) in animal species other than MAMMALS. For chickens, use CHICK EMBRYO.Animals, Newborn: Refers to animals in the period of time just after birth.Nutritional Requirements: The amounts of various substances in food needed by an organism to sustain healthy life.Biological Evolution: The process of cumulative change over successive generations through which organisms acquire their distinguishing morphological and physiological characteristics.Kinetics: The rate dynamics in chemical or physical systems.Body Patterning: The processes occurring in early development that direct morphogenesis. They specify the body plan ensuring that cells will proceed to differentiate, grow, and diversify in size and shape at the correct relative positions. Included are axial patterning, segmentation, compartment specification, limb position, organ boundary patterning, blood vessel patterning, etc.Receptors, Notch: A family of conserved cell surface receptors that contain EPIDERMAL GROWTH FACTOR repeats in their extracellular domain and ANKYRIN repeats in their cytoplasmic domains. The cytoplasmic domain of notch receptors is released upon ligand binding and translocates to the CELL NUCLEUS where it acts as transcription factor.Immunologic Memory: The altered state of immunologic responsiveness resulting from initial contact with antigen, which enables the individual to produce antibodies more rapidly and in greater quantity in response to secondary antigenic stimulus.Diet, Reducing: A diet designed to cause an individual to lose weight.Random Allocation: A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.Chromosomes: In a prokaryotic cell or in the nucleus of a eukaryotic cell, a structure consisting of or containing DNA which carries the genetic information essential to the cell. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)Minichromosome Maintenance Complex Component 4: A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It is also found in tightly-bound trimeric complex with MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 6 and MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 7.Culture Media: Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.Muscle, Skeletal: A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.Fluorescent Antibody Technique: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.Cadherins: Calcium-dependent cell adhesion proteins. They are important in the formation of ADHERENS JUNCTIONS between cells. Cadherins are classified by their distinct immunological and tissue specificities, either by letters (E- for epithelial, N- for neural, and P- for placental cadherins) or by numbers (cadherin-12 or N-cadherin 2 for brain-cadherin). Cadherins promote cell adhesion via a homophilic mechanism as in the construction of tissues and of the whole animal body.Actins: Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filaments (known also as filamentous or F-actin) can be dissociated into their globular subunits; each subunit is composed of a single polypeptide 375 amino acids long. This is known as globular or G-actin. In conjunction with MYOSINS, actin is responsible for the contraction and relaxation of muscle.Multiprotein Complexes: Macromolecular complexes formed from the association of defined protein subunits.RecQ Helicases: A family of structurally-related DNA helicases that play an essential role in the maintenance of genome integrity. RecQ helicases were originally discovered in E COLI and are highly conserved across both prokaryotic and eukaryotic organisms. Genetic mutations that result in loss of RecQ helicase activity gives rise to disorders that are associated with CANCER predisposition and premature aging.DNA, Mitochondrial: Double-stranded DNA of MITOCHONDRIA. In eukaryotes, the mitochondrial GENOME is circular and codes for ribosomal RNAs, transfer RNAs, and about 10 proteins.Escherichia coli: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.Genotype: The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.S Phase: Phase of the CELL CYCLE following G1 and preceding G2 when the entire DNA content of the nucleus is replicated. It is achieved by bidirectional replication at multiple sites along each chromosome.Selection, Genetic: Differential and non-random reproduction of different genotypes, operating to alter the gene frequencies within a population.Phylogeny: The relationships of groups of organisms as reflected by their genetic makeup.Enzyme Inhibitors: Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.Antineoplastic Combined Chemotherapy Protocols: The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.Forkhead Transcription Factors: A subclass of winged helix DNA-binding proteins that share homology with their founding member fork head protein, Drosophila.Schizosaccharomyces: A genus of ascomycetous fungi of the family Schizosaccharomycetaceae, order Schizosaccharomycetales.Embryonic Development: Morphological and physiological development of EMBRYOS.Polycomb Repressive Complex 1: A multisubunit polycomb protein complex with affinity for CHROMATIN that contains methylated HISTONE H3. It contains an E3 ubiquitin ligase activity that is specific for HISTONE H2A and works in conjunction with POLYCOMB REPRESSIVE COMPLEX 2 to effect EPIGENETIC REPRESSION.Kidney: Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.Zebrafish Proteins: Proteins obtained from the ZEBRAFISH. Many of the proteins in this species have been the subject of studies involving basic embryological development (EMBRYOLOGY).Gene Expression Regulation, Plant: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in plants.Regeneration: The physiological renewal, repair, or replacement of tissue.Antibodies, Monoclonal: Antibodies produced by a single clone of cells.Protein Isoforms: Different forms of a protein that may be produced from different GENES, or from the same gene by ALTERNATIVE SPLICING.Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)United StatesMice, Inbred BALB CObesity: A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).Sequence Alignment: The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.
Maintenance and sustained use of insecticide-treated bednets and curtains three years after a controlled trial in western Kenya. (1/58)In large experimental trials throughout Africa, insecticide-treated bednets and curtains have reduced child mortality in malaria-endemic communities by 15%-30%. While few questions remain about the efficacy of this intervention, operational issues around how to implement and sustain insecticide-treated materials (ITM) projects need attention. We revisited the site of a small-scale ITM intervention trial, 3 years after the project ended, to assess how local attitudes and practices had changed. Qualitative and quantitative methods, including 16 focus group discussions and a household survey (n = 60), were employed to assess use, maintenance, retreatment and perceptions of ITM and the insecticide in former study communities. Families that had been issued bednets were more likely to have kept and maintained them and valued bednets more highly than those who had been issued curtains. While most households retained their original bednets, none had treated them with insecticide since the intervention trial was completed 3 years earlier. Most of those who had been issued bednets repaired them, but none acquired new or replacement nets. In contrast, households that had been issued insecticide-treated curtains often removed them. Three (15%) of the households issued curtains had purchased one or more bednets since the study ended. In households where bednets had been issued, children 10 years of age and younger were a third as likely to sleep under a net as were adults (relative risk (RR) = 0. 32; 95% confidence interval (95%CI) = 0.19, 0.53). Understanding how and why optimal ITM use declined following this small-scale intervention trial can suggest measures that may improve the sustainability of current and future ITM efforts. (+info)
Planning factors for developing an enterprise-wide picture archiving and communication system maintenance program. (2/58)Picture archiving and communication system (PACS) maintenance on an individual site basis has historically been a complex and costly challenge. With the advent of enterprise-wide PACS projects such as the Virtual Radiology Environment (VRE) project, the challenge of a maintenance program with even more complexities has presented itself. The approach of the project management team for the VRE project is not one of reactive maintenance, but one of highly proactive planning and negotiations, in hopes of capitalizing on the economies of scale of an enterprise-wide PACS maintenance program. A proactive maintenance program is one aspect of life-cycle management. As with any capital acquisition, life-cycle management may be used to manage the specific project aspects related to PACS. The purpose of an enterprise-wide warranty and maintenance life-cycle management approach is to maintain PACS at its maximum operational efficiency and utilization levels through a flexible, shared, yet symbiotic relationship between local, regional, and vendor resources. These goals include providing maximum operational performance levels on a local, regional, and enterprise basis, while maintaining acceptable costs and resource utilization levels. This goal must be achieved without negatively impacting point of care activities, regardless of changes to the clinical business environment. (+info)
Specifications for equipment used for infant pulmonary function testing. ERS/ATS Task Force on Standards for Infant Respiratory Function Testing. European Respiratory Society/ American Thoracic Society. (3/58)The aim of this position paper is to define minimal performance criteria for the separate items comprising equipment used to measure respiratory function in infants together with overall performance criteria for the assembled pieces of such equipment. These guidelines cover numerous aspects including: 1) safety, 2) documentation and maintenance of equipment, 3) physical characteristics of mechanical parts and signal transducers, and 4) data acquisition. Further, validation procedures for individual components as well as for the integrated equipment are recommended. Adherence to these guidelines should ensure that infant lung function measurements can be performed with an acceptable degree of safety, precision and reproducibility. They will also facilitate multicentre collection of data and performance of clinical investigations. Manufacturers of infant respiratory function equipment should make every effort to comply with these guidelines, which represent the current standards of paediatric health professionals in this field. (+info)
Asthma risk, cleaning activities and use of specific cleaning products among Spanish indoor cleaners. (4/58)OBJECTIVES: Recent studies have shown an excess risk of asthma for cleaners, but it is not clear which cleaning-related exposures induce or aggravate asthma. METHODS: Risk factors for asthma were studied among indoor cleaners participating in the Spanish part of the European Community Respiratory Health Survey in 1992. In 1998, 78 of the 91 subjects reporting cleaning-related jobs in 1992 were identified. Of these, 67 indoor cleaners were interviewed by telephone about their cleaning activities and their use of cleaning products in 1992. These data were related to asthma prevalence in 1992, and the cleaners were compared with a reference group of office workers. RESULTS: Asthma prevalence was 1.7 times higher [95% confidence interval (95% CI) 1.1-2.6] among the cleaners than among the referents, being highest among private home cleaners (3.3, 95% CI 1.9-5.8). The prevalence of housedust mite sensitization amounted to 28% for the home cleaners and was significantly (P<0.01) higher than for other indoor cleaners (3%), but similar to the corresponding prevalence of office workers (22%). More than half of the cleaners reported work-related respiratory symptoms. The asthma risk of the home cleaners was mainly associated with kitchen cleaning and furniture polishing, with the use of oven sprays and polishes. CONCLUSIONS: The asthma risk of Spanish cleaners is primarily related to the cleaning of private homes. This relationship may be explained by the use of sprays and other products in kitchen cleaning and furniture polishing. (+info)
The use and maintenance of visible light activating units in general practice. (5/58)AIM: The present study to investigate the use, care and maintenance of light units in everyday clinical practice was undertaken to complement light unit emission surveys, with a view to developing a protocol for light unit use and care in everyday clinical practice. METHOD: The investigative work comprised a survey of selected practices in the Blackburn area with follow-up practice visits to examine light units in situ, and to glean additional information in respect of light unit use and care in the practice environment. RESULTS: Completed questionnaires were returned by 54 of 77 selected practices--a 70% response, including information in relation to 164 light units. Subsequently, 100 (61%) of these light units were examined in 42 practices according to a standardised protocol. The use and care of the light units included in the study was found to be very variable. In addition to finding that 28 (28%) had inadequate light output (<300 mW/cm2), many of the light units were found to be damaged or repaired (47, 47%). Thirty five (35%) of the light units inspected were found to have varying amounts of material adherent to the light guide exit portal. CONCLUSION: It is concluded that practitioners should address practical aspects of their increasing reliance on light units, and to this end, guidance is offered on visible light curing and the care and maintenance of light units. (+info)
Quality assurance in health care: missions, goals, activities. (6/58)The most challenging mission of medical personnel today is quality assurance in health care. To meet this challenge, the essential elements of a six-phase system for total quality control for the medical laboratory are outlined under the headings of design control, incoming material control, process control, output control, reliability control, and special verification studies. Review of existing goals and activities of programs related to this mission indicates both problems and rich opportunities for individual laboratory professionals and their organizations. For effective implementation of this mission, the laboratory professionals will have to create the atmosphere of a collegium where all interested scientists communicate across disciplines to eliminate the systematic biases and improve the accuracy, precision, and specificity of clinical laboratory measuring systems, to assure medically meaningful and useful assay results for the broad spectrum of health care that is necessary for the well, the near-well, and the sick. (+info)
Sphygmomanometers in use in general practice: an overlooked aspect of quality in patient care. (7/58)OBJECTIVES: To assess the condition, accuracy and safety of mercury and anaeroid sphygmomanometers in use in general practice and to pilot a scheme for sphygmomanometer maintenance within the district. DESIGN: Instruments were checked on site according to set protocols which related to established guidelines and standards and data were entered into a specially designed database. Mercury sphygmomanometers were removed to the laboratory for servicing. Practices received written feedback on the condition of each instrument checked, repairs undertaken and advice, where necessary, for further work required. Participant views on the scheme were sought. MATERIALS AND METHODS: A total of 472 instruments (75.4% mercury) located in 86 general practices (87.8% of practices participated) in a health district in the West Midlands. Instruments were checked against 28 (mercury) and 25 (anaeroid) quality standards and (for mercury instruments) against British Hypertension Society guidelines. RESULTS: 69.1% of mercury and 95.7% of anaeroid instruments checked, had no service records. Of the remainder, only 29 mercury (8.1%) and one anaeroid (0.9%) had a record of a check or service within the previous 12 months. None of the instruments met all of the relevant quality standards and 14 (3.9%) mercury and seven (6.1%) anaeroid instruments met less than half. A large proportion of mercury sphygmomanometers tested had defects likely to affect recommended measurement technique. Only two-thirds were accurate at all pressure levels tested. Only 38.8% of anaeroid instruments were accurate at all test pressure levels. CONCLUSIONS: The level of defects noted could have an impact on diagnosis and monitoring of hypertension. (+info)
Is home renovation or repair a risk factor for exposure to lead among children residing in New York City? (8/58)Children can be lead poisoned when leaded paint is disturbed during home renovation or repair. We conducted a case-control study to assess the association between elevated blood lead levels (BLLs) in children younger than 5 years of age and renovation or repair of homes built before 1950 in New York City. In 1998, we interviewed parents of 106 case children (BLLs >/= 10 micro g/dL) and 159 control children (BLLs +info)
Lead-Based Paint Operations & Maintenance Work Practices Manual for Homes and Buildings | WBDG Whole Building Design Guide
This Manual is written to guide users in the safe management of lead-based paint, commonly encountered during the operation and maintenance (O&M) of homes and buildings. These procedures will help the user to: (1) control the creation of lead-contaminated dust, (2) control the scattering (dispersion) of this dust, (3) effectively clean up lead-contaminated dust and debris created by the work being done, and (4) protect the workers health and safety. This Manual provides maintenance guidance to two different groups. The first group includes owners of single family residences and owners of small (3 or 4 unit) apartment buildings who do their own maintenance work. Manual users in this group should next read Chapter 2, and then may skip to Chapters 5 and 6. The second group includes owners and managers of multi-family residential or public and commercial buildings. Operations and Maintenance (O&M) work in these types of buildings may be performed by in-house staff or contracted to outside ...
NEB - ARCHIVED - Public Comment Period - Operations and Maintenance Activities on NEB-Regulated Facilities: Requirements and...
NEB - ARCHIVED - Regulation of Operations and Maintenance Activities on Pipelines Under the National Energy Board Act and...
In any power station, heat is created to power turbines in order to generate electricity. Unless there is sufficient insulation...
HSP produces quality tailor-made products and services such as transformer bushings, switchgear bushings, generator bushings, HVDC bushings and SF6-bushings up to the highest service voltage, as well as service and maintenance work for HSP equipment, service and maintenance work for other equipment and training for customers. ...
LTC waits drive up ALC patients in hospitals, despite reductions in admissions of ambulatory care patients
There are long-term ongoing disputes with privatized P3 contractors over the P3 agreements, including about what is covered by the P3 (or "AFP" as the government likes to call them) contract.The hospitals are required to pay higher than reasonable rates tothe P3 contractor for maintenance work the contractor has deemed to be outside of the P3 contract. Hospitals are almost forced to use P3 contractors to do maintenance work the contractors deem outside of the P3 contract or face the prospect of transferring the risk associated with maintaining the related hospital assets from the private-sector company back to the hospitalP3 companies with poor perf ...
Home repairs and maintenance - Work and Income
One (1) Custodian, 3.5 hrs., Boyd E. Smith - 12 months job in Cincinnati, OH - Cincinnati Enquirer
Custodian - Substitute job in Cincinnati, OH - Cincinnati Enquirer
Springfield City School District Custodian Granted PTD | Monast Law Office
DPS in search of 70 custodians as schools prepare to re-open | FOX31 Denver
Schools are being cleaned more thoroughly. Stressed-out custodians would like to get some help, and see a provincial standard |...
School Custodian/Janitor, Delta T Group (Woodbridge) - Continuing EducationContinuing Education
Fairleigh Dickinson University custodian
CIO as a custodian of IT assets
Many years ago, as I was submitting the summary of our findings of study to the CEO of a client organization, his remarks stayed on with me for long. Our assignment was to assess the efficacy of their IT program, and suggest improvements in its functioning. Amongst other things, we found that some of the IT assets like PCs, printers were bought but not utilized; similarly, some software solutions were not implemented due to disagreement with the users. As expected, the CEO was disappointed, and said that he expected his CIO to be more responsible.. The CEO considered his CIO to be the custodian of all IT assets -one who ensured that right solutions are bought and put to proper use. When the CIO asks for a budget and subsequent buys, he clears them in good faith with the expectation that he would look up to the CIO to take care of them. I thought that these were significant remarks which clearly demonstrated the CEOs expectations and consequences of the CIO not living up to those ...
"Season of Giving": Teacher saves custodian's life with kidney donation - CBS...
Centralia College custodian
Wichita State University custodian
CONFIG SYS [DI]CACHE OFF: convert to Kconfig (a0aba8a2) · Commits · U-Boot / Custodians / TI ARM U-Boot Custodian Tree · GitLab
Kenya's push for nuclear power rests on false premises
A recent study by a German engineering consultancy further confirmed how exaggerated government figures about demand have been. It noted that Kenyas maximum power demand would grow 72% to 2,259MW by 2020 from the current 1,620MW when projects such as the standard gauge railway start operating fully.. Government estimates, on the other hand, project peak demand will jump threefold to 4,755 megawatts in the three-year period. This is twice as much as the consultants estimates.. On top of this, Kenyas problem isnt that it needs more energy. Rather it needs to address distribution issues.. Any project involving the generation of more power needs to pay equal attention to Kenyas grid and distribution system which currently cant handle additional power. This includes corresponding efforts at regular, systematic maintenance work. Without these, any extra power generated from renewable and other energy sources will remain costly and wasted.. Yet another note of caution is in order. Demand from ...
Costa Cruises Invests 22 Million Euros in Fleet Maintenance
Dane County Chapter - Burn Brush Piles @ Glacial Valley Conservancy - Ice Age Trail Alliance
We will be cutting invasive brush and trees with hand tools, treating stumps and making brush piles along the central portion of the Cross Plains Segment. This type of trail maintenance work helps native wildflower species thrive come spring and creates a beneficial habitat for wildlife including birds, bees, and butterflies.. If you are a certified sawyer (chainsaw) and own personal protective equipment (PPE), please bring both. If youre not certified to operate a chainsaw, but own PPE, you may bring it so you can work in tandem with a certified sawyer.. I will provide herbicide and loppers. I will also provide some food to share for lunch, including brats to cook on the fire.. Please bring work gloves and wear long sleeves to protect against the brush. If you need work gloves or protective eye glasses, let me know. If you like the warmth of a fire, you should be wearing wool or cotton as an outer layer. Fleece and synthetics will melt as a spark hit them. A sweatshirt on top of these will ...
Dane County Chapter - Brush Pile Burning, Moraine Kettles - Ice Age Trail Alliance
We will be cutting invasive brush and trees with hand tools, treating stumps and making brush piles along the central portion of the Verona Segment. This type of trail maintenance work helps native wildflower species thrive come spring and creates a beneficial habitat for wildlife including birds, bees, and butterflies.. If you are a certified sawyer (chainsaw) and own personal protective equipment (PPE), please bring both. If youre not certified to operate a chainsaw, but own PPE, you may bring it so you can work in tandem with a certified sawyer.. I will provide herbicide and loppers. I will also provide some food to share for lunch, including brats to cook on the fire.. Please bring work gloves and wear layers of long sleeves to protect against the brush. If you need work gloves or protective eye glasses, let me know. If you like the warmth of a fire, you should be wearing wool or cotton as an outer layer. Fleece and synthetics will melt as a spark hit them. A sweatshirt on top of these will ...
Surveillance for Waterborne Disease and Outbreaks Associated with Drinking Water and Water not Intended for Drinking --- ...
Etiologic agents Legionella spp. and chemicals were the most commonly reported etiologic agents in drinking water-associated WBDOs. During 2003--2004, eight reported drinking water-associated WBDOs involved Legionella spp. and comprised 26.7% of the total, which is only the second time that data concerning Legionella outbreaks have been included in a Surveillance Summary. Chemical/toxin drinking water-associated WBDOs (n = eight) comprised 26.7% of the total, an increase from the previous surveillance period and the largest number of chemical/toxin-related drinking water WBDOs since the 1993--1994 surveillance period. Of the eight chemical/toxin WBDOs, three (37.5%) resulted from deficiencies related to drink mix/soda machines, and two (25.0%) resulted from deficiencies related to recent maintenance work. These outbreaks stress the importance of proper installation and maintenance of water systems and equipment. The increased number of chemical/toxin-related outbreaks also emphasizes the need ...
HSE Web Communities - Asbestos Licensing Information
List of current asbestos licence holders with addresses. A list of the licence condition numbers is available in the General Information section of this community. Please note that these are standard wordings - the wording on the actual licence may differ slightly in some circumstances. Some full licence holders have condition 19 added to their existing standard licence to allow them additionally to carry out maintenance work. The type of licence held by the company is available in the Licence Type column, but if in any doubt, you should contact the company direct and ask to see a copy of their licence. Page 3 shows standard conditions attached to Asbestos Licences specifically issued to Maintenance Licence Holders. Note: Some Full Licence holders are also permitted to erect scaffolding, if they have suitably trained staff - you should contact the licence holder direct for details ...
Nokia water supply contamination - Wikipedia
The Nokia water supply contamination occurred from November 28 to 29, 2007, when a large part of the water supply in Nokia, Finland, was contaminated with treated sewage water. The contamination affected an area with some 12,000 inhabitants and caused an epidemic of thousands of cases of diarrhea and vomiting primarily due to Norovirus and Campylobacter infections. Hundreds of inhabitants were hospitalised, and the town was forced to temporarily forbid all use of tap water. The cause of the contamination was revealed to be a combination of different events. A maintenance man in the Nokia waterworks had opened a valve between tap water and sewage water pipes to let some tap water flush out the sewage pipe. The valve had been previously installed against regulations. Because of pressure differences, the water flowed in the opposite direction, contaminating the tap water. At the same time, maintenance work was being carried out at another site, so the first calls from people complaining about the ...
NIOSHTIC-2 Publications Search - 20026976 - Facilities journeyman electrician electrocuted while doing electrical maintenance...
A 35-year-old white male facilities journeyman electrician (victim) was electrocuted while doing electrical maintenance work on a power mound (transformer) in a shipyard. The power mound provided power to numerous essential power activities including shipboard activities, confined spaces, lighting, and power handtools. The incident site (south power mound) was located outside in the southern porti
Offshore turbine maintenance with Huisman | Article | KHL
Physical condition synonyms, physical condition antonyms - FreeThesaurus.com
Yamaha XQ150 Service manual
XQ125 XQ150 2001 5HT1-AE2 SERVICE MANUAL EASM0000 XQ125 / XQ150 SERVICE MANUAL © 2001 by MBK Industrie 2nd edition, April 2001 All rights reserved. Any reproduction or unauthorized use without the written permission of MBK Industrie is expressly prohibited. EASM0001 NOTICE This manual was produced by the MBK Industrie primarily for use by Yamaha and MBK dealers and their qualified mechanics. It is not possible to include all the knowledge of a mechanic in one manual. Therefore, anyone who uses this book to perform maintenance and repairs on Yamaha and MBK vehicles should have a basic understanding of mechanics and the techniques to repair these types of vehicles. Repair and maintenance work attempted by anyone without this knowledge is likely to render the vehicle unsafe and unfit for use. MBK Industrie is continually striving to improve all of its models. Modifications and significant changes in specifications or procedures will be forwarded to all authorized Yamaha and MBK dealers and will ...
Re^3: Practical example of 'Is Perl code maintainable'
than is ever spent actually making the modifications. Even when working in a language with which you are almost completely unfamiliar (MicroFocus COBOL is so far removed and extended over the primitive version I learnt at collage in the early 80s, that it is, for all intents and purposes, a completely different language. It has pointers and dynamic memory allocation for dogs sake!), that the time spent understanding the syntax of individual lines of code, or even whole subroutines is very minor when compared to analysing the structure of the surrounding code and how the changes will affect it. Indeed, I think that a certain amount of terseness and lack of clarity is a good thing. Anything that makes the follow on programmer stop and think and analyse rather than practicing hit&run maintenance is a good thing in my book. About half of all the maintenance work I did on that rdbms was re-work. Fixing bugs introduced by previous maintenance. In most cases it meant locating and backing out the ...
Monitoring Behavior Reactions to Washington Metro SafeTrack Project Using Advanced Travel Data Collection Techniques -...
The recent network disruptions in the Washington Metro system showed the new reality associated with aging transit infrastructure and highlighted the potential severity of such disruptions. However, relevant studies in the literature are limited and agencies need more empirical evidence to help them better planning and implementing maintenance work.. To fill this research gap, this study analyzed both aggregated ridership data of the Washington Metro system collected from the National Transit Database, and the individual travel survey data collected from a National Science Foundation project to provide more empirical evidence on behavioral reactions to transit network disruptions. Particularly, this study highlighted the long-term impact of such disruptions on transit ridership, and the issues related to using stated preference or attitude survey data alone for planning purposes. Findings from this study would help transit agencies to better plan for future maintenance needs. ...
Where we use a customers equipment to carry out maintenance work, were able to offer a storage and inspection service for these items. Telecommunications Sector Services We have space available that you can hire to store your own business assets and items. We also have space available at Didcot Stores that you can hire to store your spares and cable items. Well treat your assets as we do our own, however they will be specifically coded to track and access them. Please get in touch to discuss your requirements.. Make an enquiry. ...
Maui County, HI - Official Website
The Department of Parks and Recreation announces the closure of the Kihei Aquatic Center training pool from Oct. 14 to Oct. 16, 2020, for repair and maintenance work on a pipeline.. The pool is scheduled to reopen Oct. 17. Pool hours are from 9 a.m. to 4 p.m.. The aquatic centers 50-meter pool will remain open for lap swimming during the closure of the training pool for maintenance.. For more information, contact Duke Sevilla, Pool Manager, at [email protected] or call (808) 270-6135.. For general Parks & Recreation information, visit www.mauicounty.gov/parks.. ...
Waschke, K F<...
Handyman / Home Improvement
A handyman, also known as a handyperson or handyworker, is a person skilled at a wide range of repairs, typically around the home. These tasks include trade skills, repair work, maintenance work, are both interior and exterior, and are sometimes described as "side work", "odd jobs" or "fix-up tasks". Specifically, these jobs could be light plumbing jobs such as fixing a leaky toilet or light electric jobs such as changing a light fixture. can part 4 linda asselbergs knack smx h.d. air ride western saddle pad shiloh mom s house dad s house pdf files la isla de creta yasuo poster contest for elementary citation gauvain yvaine galli casa agenzia immobiliare roma female ob gyn rock hill sc jobs laura dalgliesh solicitor general of texas net tools vs iproute2 utility li rong hao wo shi ge shou 2016 historia japonessa hilo rojo feng nancy schlichting married 13520 lemoli ave impregnowanie drewna scary movies filmed in wilmington nc glasblazen etten leur 319b military spouse fallout 3 guia ps3 error ...
Swedish nuclear reactor shut after sea water infiltration | Nuclear power in Europe
Stockholm, Dec 21: A reactor in Swedens biggest nuclear plant was stopped after an infiltration of sea water, the operator Vattenfall and the national nuclear industry watchdog said.. "There is no safety problem" at Reactor 4 at the Ringhals plant near Gothenburg in the countrys southwest, nuclear authority inspector Jan Gsjo told the national TT news agency.. He added that the presence of salt water in the pressurised water system was nonetheless an anomaly which needed to be fixed.. Earlier this month, a reactor at another Swedish nuclear plant was shut down after the nuclear watchdog said the operator had failed to comply with its safety requirements, safety officials said.. The Oskarshamn plants number two reactor was taken out of service after the operator was unable to show the Swedish Radiation Safety Authority that standard maintenance work had been performed on two diesel generators used for emergency power supply.. Some 35 per cent of electricity in Sweden is generated from nuclear ...
Health care | Department of Veterans' Affairs
The SHOAMP Health Care Scheme provides treatment and counselling for eligible personnel who were involved in F-111 deseal/reseal and fuel tank maintenance work. The SHOAMP Health Care Scheme also provides counselling for family members of Group 1 participants, and other personnel employed at RAAF Base Amberley at the time of the F-111 deseal/reseal programs.
Handyman / Home Improvement
A handyman, also known as a handyperson or handyworker, is a person skilled at a wide range of repairs, typically around the home. These tasks include trade skills, repair work, maintenance work, are both interior and exterior, and are sometimes described as "side work", "odd jobs" or "fix-up tasks". Specifically, these jobs could be light plumbing jobs such as fixing a leaky toilet or light electric jobs such as changing a light fixture. gun for pz 4 j gangway monsters walkthrough for resident hndkastan siro patmutyun serial podcast redwater calgary sw preparazione tavolo per matrimonio lightroom midi windows api printeks prizren kosovo terraza per shitje motorrash nigeria yoruba muslim music inazuma eleven final episode 1308-2 fox news sunday january 17 2016 carlson vit e suppositories overdose ciara download mp3 cod war heart of the reich theme goth electronica pasta di campofilone spinosi pasta adp diphosphate catullo viviamo mia lesbia e amiamoci ceojuice login hcenc tutorial on excel tavan ...
U.S. war readiness in jeopardy as pilots flee
Sequestration cuts arent limited to the Air Force.. The Army is shrinking the number of troops to 380,000. Gen. Raymond Odierno, Army chief of staff, in the same Senate Armed Services Committee hearing, expressed particular concern that force reductions have greatly affected its readiness capability between 2014-2017.. The Marine Corps will be limited to 150,000 troops.. The Navy will be cut three carriers, after already having reduced the number of capital ships to some 260, down from the 600 reached at the peak of the Reagan administration.. New Navy flag officers and executives have been told to begin more cuts under sequestration, in which some 3,000 temporary civilian personnel will be laid off, and base operations will be reduced.. In addition, there is to be a cancellation of maintenance work on some 30 Navy ships and 250 aircraft.. The cutbacks come as the Navy continues to operate under 2012 budget levels because of a congressional continuing resolution. Like the other services, the ...
Petzl to Debut New DUO Headlamps at FDIC International 2018 - Fire Apparatus
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Service Alerts | Digital Services | Stanford Medicine
Date Reported: November 14, 2018. Issue: Some authors are experiencing error messages upon login to AEM, lack of access to websites and/or assets and the inability successfully publish pages.. Impacted Groups: Any author who was added to AEM or who had new site rights granted after June 2018 may be impacted by access issues. All authors may be impacted by pages not successfully being published.. Cause: An error related to syncing author and permissions data occurred during AEM maintenance work on Tuesday evening. Action: Please submit a help ticket if you are experiencing any of these issues.Include the name(s) of the website(s) you are unable to access.. Updates:. 11/15/18, 3:15 ...
December 31, 2013 - ISS On-Orbit Status Report
Combustion Integrated Rack (CIR) Hardware Replacement: FE-3 Hopkins used the Maintenance Work Area (MWA) for restraining the Multi-user Droplet Combustion Apparatus (MDCA) Chamber Insert Assembly (CIA) while he installed fuel reservoirs, replaced two igniter tips and exchanged manifold bottles to prepare for future operations.. ISS InterModule Ventilation (IMV) Airflow Measurement: In support of monitoring the health of the ISS InterModule Ventilation (IMV) system, FE-5 Mastracchio and FE-6 Wakata used the Velocicalc device and a set of measurement aids to measure the air flow outlets and inlets throughout the USOS modules. In addition to flow rate measurements, inspections were performed in selected locations including the Airlock IMV Panel Screen on the IMV air return port and Node 3 inlet vents.. USOS Airlock Restow and Deconfiguration Post US EVA 25: Mastracchio deconfigured the Airlock post US EVAs 24 and 25 and prepared the EMUs for long-term stowage. EVA hardware that was moved out of the ...
Exploration - a-n The Artists Information Company
Arnold Rimmer - Wikipedia
Rimmer first appeared in Red Dwarfs first episode "The End" (1988), where he is characterised as second technician on board the mining ship Red Dwarf, ranking above Dave Lister (Craig Charles), the lowest ranked crew member on board the ship with whom he shares quarters, and below all four of the service robots. As a technician, Rimmer does maintenance work on chicken soup vending machines that not even the robots are assigned to. Rimmer is shown having difficulty revising for his "engineers exam" which he hopes to pass and become an officer after having failed before prior to the episode, and reveals that he wasnt academy educated unlike others who had become officers. After Lister is awakened from stasis, where he was put as punishment for bringing an unquarantined cat on board, the ships computer Holly (Norman Lovett) tells Lister that the ships crew died in a radiation leak from a drive plate Rimmer had improperly repaired and Lister was kept in stasis until the radiation levels ...
UC Berkeley to cut down trees in People's Park for safety - Berkeleyside
Lost Hospitals of London
Present status (September 2008). The site contains many buildings of various ages and architectural styles, some permanent and some temporary. Many look neglected and their exteriors need maintenance work.. The future of the Hospital has been under discussion for over a decade, with proposals to close the Accident and Emergency Department, replacing it with an Urgent Care Centre, and to move maternity services to Barnet Hospital and the North Middlesex Hospital.. ...
Hurricane aorta - Zurich Open Repository and Archive
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SNCF TGV Iris 320
Naval Station Everett
"Maintenance". Real Digital. 31 March 2012. "BT wins right to take Sky Sports price ruling to court of appeal". The Guardian. 26 ... Real Digital claim to be undergoing essential maintenance work, with the signal going offline for approximately 7 days. The ... The service ceased transmitting on 31 March 2012 to "undergo essential maintenance work", and promised to return in ...
Piscataqua River Bridge
River Rother, East Sussex
Configuration management database
The maintenance of such state related information allows for things like the reconstruction of such assets, at any point in ... This maintenance is a significant undertaking that is often not planned for or expected. Organizations often find this the ... Maintenance. Companies face constant change. Data about CI's and the relationships between them are constantly changing. ...
2015 Parapan American Games
Woodbridge, Irvine, California
Port of Grimsby
The operations and maintenance centre was to be sited adjacent to the berth on the northeast corner of the quayside. Parts of ... The Fish docks and nearby estate were devoted to the landing of fish, and maintenance, supply and repair of the Grimsby fishing ... In 2013 Dong Energy selected the Royal Dock as an operation and maintenance centre for the Westermost Rough Wind Farm. As part ... In 2012 Centrica opened an operations and maintenance base on the north wall (fish dock), for use with the Lynn and Inner ...
Importantly, without maintenance there can be no champerty." Unlike the above, a case bond is merely supplied, with no ... Maintenance "...is directed against those who, for an improper motive, often described as wanton or officious intermeddling, ... However, the definition of Champerty and/or Maintenance differs between states. In many states, it is no longer part of the law ... In the Common law of England, the practice of financing lawsuits was connected with champerty and maintenance, which was a ...
Canadian Coast Guard
Bibliography of Western Sahara
The President's Challenge
"Site Maintenance". The President's Council on Fitness, Sports & Nutrition. Retrieved January 19, 2012. "We apologize for the ... The President's Challenge website said it was down for "Site Maintenance - We're taking a little breather." On January 20, 2012 ... site maintenance. We will be back up soon". The President's Council on Fitness, Sports & Nutrition. Retrieved January 20, 2012 ...
National Roads Authority
Better maintenance. Class hierarchies not only facilitate re-use they also facilitate maintenance of systems. By having one ... In order to limit the risk associated with the development and maintenance of KBE application, there is a need to rely on an ... such as hypothetical reasoning and truth maintenance. Simkit added stochastic simulation capabilities to the KEE environment. ...
Maintenance planning is solving an optimisation problem and it can be predictive. In predictive maintenance planning empirical ... "Highway Maintenance." The Handbook of Highway Engineering. Ed. T.W. Fwa. CRC Press, 2005. Walker, Derek and Kumar, Arun. " ... Developed countries are constantly faced with high maintenance cost of aging transportation highways. The growth of the motor ... The overall purpose of highway maintenance is to fix defects and preserve the pavement's structure and serviceability. Defects ...
Maintenance Workers, Machinery
Maintenance/ Troubleshooting | STMA
Maintenance/ Troubleshooting Maintenance and Troubleshooting for Sports Facilities. Annual Maintenance Calendars. Annual ... Preventative Maintenance Log Example (for North Scott Community School District). Preventative Maintenance Log (adaptable to ... Field Maintenance Costing Spreadsheet Example (for North Scott Community School District). Field Maintenance Costing ... Annual Athletic Field Maintenance Calendar for the Transition Zone. University Resources:. Northwest:. Maintenance Standards ...
Home repairs and maintenance - Work and Income
Offshore turbine maintenance with Huisman | Article | KHL
Huisman has developed a new high reach lightweight crane design that can be mounted on a small jack-up vessel for maintenance ... for maintenance. With this new crane type we believe to have designed a cost-effective means to perform maintenance on existing ... Storing the lifting hooks inboard simplifies inspection and maintenance. Extra boom clearance is gained by tilting the knuckle ... International lifting and offshore services specialist Huisman has developed a new crane series for maintenance work on ...
Predictive Maintenance solution
... predict when your equipment needs maintenance, and preemptively service that equipment before problems occur. ... Predictive Maintenance solution. This solution helps you move beyond your preventive maintenance program to predict when your ... The Predictive Maintenance solution gives you better visibility into equipment status, letting you resolve issues before they ... Preventive Maintenance using DDP. Accurately view asset health, predict asset downtime, prioritize and allow for timely ...
Computer maintenance - Wikipedia
When major maintenance such as patching is performed, a backup is recommended as the first step in case the update fails and ... Computer maintenance is the practice of keeping computers in a good state of repair. A computer containing accumulated dust and ... Operating-system files such as the Windows registry may require maintenance. A utility such as a registry cleaner may be used ... Disk cleanup may be performed as regular maintenance to remove these. Files may become fragmented and so slow the performance ...
BREAKING DOWN Maintenance Bond. A surety bond is a three-way contract where a third party called the surety guarantees the ... DEFINITION of Maintenance Bond. A type of surety bond purchased by a contractor that protects the owner of a completed ... A maintenance bond is not technically insurance, but basically functions as an insurance policy on a construction project to ... Pricing a maintenance bond is very different from pricing regular coupon paying bonds. ...
Collection: Trails Cleanup & Maintenance
High Maintenance | Billboard
Boeing: Maintenance Training
ME/AV Cat II licensed airplane engineers who perform airplane maintenance under the Civil Aviation Administration of China ( ... This course is designed for maintenance technicians with BBJ experience who require an airplane systems review. This course ... B1/B2 licensed airplane engineers who perform airplane maintenance under the Civil Aviation Safety Agency (CASA) Regulations as ... B1/B2 licensed airplane engineers who perform airplane maintenance under the European Aviation Safety Agency (EASA) Regulations ...
phpBB • Server Maintenance
Aviation Maintenance Alerts
Maintenance - gas pipework
... The requirement for landlords to provide domestic gas maintenance is distinct from the requirement ... Who can do the maintenance?. All maintenance checks and repairs must be done by a Gas Safe registered engineer. ... Maintenance from the meter to the service pipework (external to the property) is not the responsibility of the landlord but the ... The contract you make with your tenant should allow you access for any maintenance or safety check work that needs to be done. ...
Installation, Maintenance, and Repair Occupations
Electronic and Precision Equipment Repair and Maintenance 54,280. 52.36. $21.70. $45,140. Automotive Repair and Maintenance ... Maintenance, and Repair Workers ; Installation, Maintenance, and Repair Workers, All Other National estimates for this ... Automotive Repair and Maintenance 442,500. 48.70. $19.87. $41,330. Building Equipment Contractors 390,090. 19.58. $22.99. $ ... Personal and Household Goods Repair and Maintenance 29,090. 38.27. $19.24. $40,030. Wired Telecommunications Carriers 205,760. ...
IBM Predictive Maintenance - Details - Kuwait
Unifies disparate operational data into analytics driven predictive maintenance models that improve asset reliability and ... IBM Predictive Maintenance. Unifies disparate operational data into analytics driven predictive maintenance models. Improves ... analysis will prescribe maintenance be preponed to avoid asset failure or postponed to avoid unnecessary maintenance. ... and event data to prescribe optimum asset maintenance schedules, allocate resources, and reduce maintenance costs. ...
Predictive maintenance - United Kingdom | IBM
Predictive maintenance is the asset management practice of repairing an asset or piece of equipment before it fails based on ... Predictive maintenance breakdown. Stay up and running. Control costs.. Predictive maintenance is the asset management practice ... Corrective maintenance: repairs made after a problem or failure occurs. Preventative maintenance: scheduled repairs made based ... Or, prescribe maintenance sooner to avoid failure. Or, postpone maintenance to avoid unnecessary cost and effort. ...
Property Maintenance - Mason District Council
Welcome to the Mason District Council! The Mason District Council (MDC) is a non-profit organization designed to act as a support network and communication forum for citizens and civic associations and home owner associations within the Mason District, County of Fairfax, Virginia. The organization partners with its member-associations to promote the communitys general welfare through non-partisan, non-sectarian civic activities. This site is designed to be a resource for neighborhoods in the Mason District of Fairfax VA. We hope this site will help all communities in our district connect! If you would like your neighborhoods blog or website to be added - please email us. Connecting Your Community: Like many other districts, our neighborhoods are becoming more culturally and socio-economically diverse. Uniting the community presents a challenge in todays busy society. The MDC will serve as a system of support to those community leaders who are working hard for their neighborhoods. The MDC will
Answers about Bird Maintenance
NJ Health Maintenance Organizations
The Maintenance Cost Iceberg
... 710669. How effective and complete is the work being done in fleet garages today? Is the fault ... that maintenance improvement and cost reduction may be difficult, but certainly is not unattainable. ... Citation: Becker, F. and Hayden, C., "The Maintenance Cost Iceberg," SAE Technical Paper 710669, 1971, https://doi.org/10.4271/ ...
Muscle Maintenance - Scientific American
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Hydraulic Maintenance and Troubleshooting
Maintenance of Hydraulic Systems by Ricky Smith CMRP,... 3764 views * Maintenance of Hydraulic Systems by Ricky Smith CMRP,... ... Ahmed Galal Mazen , Mechanical Maintenance Engineer at suez steel company - Rolling Mill Plants at Suez Steel Company ... Hydraulic Maintenance and Troubleshooting * 1. Hydraulic y Troubleshooting PRESENTED BY NORMAN KRONOWITZ ...
Maintenance Update · Formstack Blog
Formstack is a workplace productivity solution built to transform the way people collect information and put it to work. With its powerful data collection and process automation capabilities, Formstack reduces data chaos and solves important business problems. Formstacks offerings include intuitive data collection products, advanced workflow functionality, payment processing capabilities, automated document generation, and a suite of advanced application integrations. To learn more, visit formstack.com.. ...
Golf Court Maintenance Trick
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Boeing: Aircraft Maintenance & Modifications
From providing scheduled maintenance operations or upgrading an avionics system to trouble-shooting a mechanical issue or ... Engineering, Modification and Maintenance Through unparalleled innovation, global presence and agile performance, Boeing Global ... Boeing provides on-site maintenance and support ensuring F/A-18 fleets (both Classic Hornets and. Super Hornets) are mission ... the remaining 70 percent of sustainment costs is where Boeings maintenance and modernization of aircraft drives affordability ...
maintenance - Hongkiat
The Certification Maintenance program links AICP-certified planners to education and training opportunities so they may earn ... Certification Maintenance. AICPs Certification Maintenance program helps planners gain the knowledge and skills they need to ... Certification Maintenance Update. We understand that many AICP members plan on the CM earned at NPC to meet their reporting ... The Certification Maintenance (CM) program links certified planners to training opportunities that keep them up to date on the ...
Pavement and Winter Maintenance - Google Books
Pavement and Winter Maintenance, Issue 1627. Pavement and Winter Maintenance, National Research Council (U.S.). Transportation ... percent present worth pressure relief joints preventive maintenance Preventive Maintenance Program preventive maintenance ... Council neural network P-value paper pave pavement and bridge pavement conditions pavement distress pavement maintenance ... books.google.comhttps://books.google.com/books/about/Pavement_and_Winter_Maintenance.html?id=-E9GAAAAYAAJ&utm_source=gb-gplus- ...
Maintenance Control Panel download | SourceForge.net
health-maintenance organization | Encyclopedia.com
Source for information on health-maintenance organization: A Dictionary of Sociology dictionary. ... so helping to reduce costs and increasing medical incentives to health maintenance. ... health-maintenance organization (HMO) A type of health-care organization developed in the USA, initially on co-operative ... health-maintenance organization (HMO) A type of health-care organization developed in the USA, initially on co-operative ...
Car maintenance you should do
But does keeping up with maintenance mean paying for every service under the sun?. Not at all, according to Bank Rate, which ... A glaring example of unnecessary maintenance is changing the engine oil too often, Bank Rate said. "It used to be normal to ... Sorting out the heavy-handed sales pitches from the very necessary maintenance that will save you money is largely a matter of ... Additionally, there are a handful of car maintenance services you shouldnt skip, Bank Rate said. Here are the sites top five: ...
U.S. GAO - Depot Maintenance
... program to compete depot maintenance workloads between the public and private sectors. ... Navy Maintenance: Navy Report Did Not Fully Address Causes of Delays or Results-Oriented Elements. GAO-21-66: Published: Oct 29 ... Depot Maintenance. NSIAD-93-292R: Published: Sep 30, 1993. Publicly Released: Sep 30, 1993.. ... Pursuant to a congressional request, GAO reviewed the Department of Defenses (DOD) program to compete depot maintenance ...
Housing Management & Maintenance - January 2018
Home Maintenance & Construction | CPSC.gov
Home Appliances, Maintenance and Construction. Technical Reports. 10/27/2017 Liquid Laundry Packet Letter to ASTM on Baseline ... Home Maintenance & Construction. Technical Reports. 05/01/2017 CPSC Staff Statement on the Industrial Economics, Inc. Report: " ... Consumer Opinion Forum, Survey #3, Clothes Dryer Maintenance 07/30/2004 Testing of Combustibles on the Heater Housings Used in ...
District 8 | Winter Maintenance & Operations
Housing Management & Maintenance - January 2018
Libraries report outlines maintenance crisis
Last year, the Center for Urban Future found the libraries are facing a $1.1 billion maintenance crisis caused by a chronic ... "As our new report vividly demonstrates, New Yorks public libraries are facing a maintenance crisis, he said. It is ... Included in the report are examples of branchs maintenance needs along with a description of the communitys profile outlining ... maintenance crisis across the citys 207 libraries.,/p, ... Libraries report outlines maintenance crisis By GLORIA PAZMINO ...
Human Factors in Aviation Maintenance
FAA Home ▸ About FAA ▸ Programs & Initiatives ▸ Human Factors in Aviation Maintenance Human Factors in Aviation Maintenance. * ... Aviation Maintenance. The overall goal of Aviation Maintenance human factors research is to identify and optimize the factors ... This page was originally published at: https://www.faa.gov/about/initiatives/maintenance_hf/ ...
UHM: St John Network Maintenance
System maintenance tasks [AX 2012]
16. PLANT MAINTENANCE AND REPAIR
Preventive Maintenance Areas: * In Appendix IV a checklist is provided to highlight generalised preventive maintenance ... PLANT MAINTENANCE AND REPAIR. The plant maintenance program is vital to consistent production of high quality feeds and no less ... Training of maintenance staff should be a high priority with high-level management oversight. Too often maintenance is seen as ... A good preventive maintenance programme should provide adequate maintenance at reasonable cost (Appendix III).. Preventive ...
Electrolyte Maintenance | Walgreens
JAL - System Maintenance
CORSAIR Site Maintenance
Maintenance of Certification
Maintenance Equipment | AHD60
ADF Maintenance Kit
Maintenance | University Housing
Maintenance. The Maintenance Staff handles most routine problems within 24-36 hours. Routine problems include, but are not ... You may report housekeeping and maintenance concerns via a work order. Work orders can be filled out online and should be ... If you fail to report room maintenance concerns as they occur you may be held liable for damages when you vacate. ...
pdfforge | Maintenance Plan
Maintenance Plan. Maintenance Plan. The best value for your business. At the time of purchase, and up to 30 days after the ... Adding the maintenance plan now gives you the opportunity to extend the maintenance for another year. You can buy the ... If Maintenance is selected, all licensed copies of your multi-user license must be covered by maintenance. When adding ... Please note that the maintenance plan has a maximum coverage period of 2 years). While you are covered by maintenance you will ...
Low-maintenance succulents make watering a breeze
Commercial Property Maintenance Newcastle | CMS Limited - YouTube
CMS Ltd offer the best commercial property maintenance services in Newcastle and across the North East UK http://cmsltd.co.uk ... Property Maintenance Glasgow Handyman Services - Total Property Scotland - Duration: 1:23. Total Property Maintenance 85 views ... Handyman Services Hamilton Scotland Property Maintenance - Total Property Scotland - Duration: 1:13. Total Property Maintenance ... Commercial Property Maintenance, Plumbers, Electricians , CMS Ltd - Duration: 0:10. CMS Ltd 14 views ...
Common Cycle Fall 2018 Maintenance Course Application
What is your current level of comfort doing basic bicycle maintenance? *. (This could include changing a flat tire, oiling a ... We cover a range of repair and maintenance from basic (e.g. tube change, brake adjustment) to advanced (e.g. hub overhaul, ... What is your current level of comfort doing advanced bicycle maintenance? *. (This could include installing a headset, or ... Common Cycles Fall 2018 Maintenance Course will begin Tuesday, October 9th and run on 6 consecutive Tuesdays from 6:30-8:30 in ...
MicroMain Announces New Mobile Maintenance Management Software
... an industry leader in maintenance and facility management software and services, announces the release of an ... MicroMain Maintenance. With Mobile, users can update their maintenance database in real-time from anywhere using any Internet- ... Weve been a maintenance software provider since 1991 and weve developed a pretty good sense of what our users are looking for ... "Weve been a maintenance software provider since 1991," Brummer said, "and weve developed a pretty good sense of what our ...
HindSite Releases Lawn Maintenance Software Buyer's Guide.
Paul, MN (PRWEB) January 20, 2015 -- HindSite Software, the leading provider of lawn maintenance software, today announced the ... Lawn Maintenance Software Buyers Guide. The new eBook is designed to help lawn maintenance businesses evaluate software when ... 1. How to identify needs and how lawn maintenance software can eliminate the biggest business issues. 2. A features guide to ... HindSite Software, the leading provider of lawn maintenance software, today announced the release of a new eBook, ...
JD Air Maintenance Package Sign Up Form
'High Maintenance' Jonathan (TV Episode 2013) -...
With over 325 years of innovation and passion, Husqvarna provides professionals with forest, park and garden products. We let high performance meet usability and safety, making you ready to get the job done efficiently. Husqvarna offers a wide and growing range of products and accessories, including everything from chainsaws and power cutters to robotic lawnmowers. ...
Web Maintenance Requirements | Department of Energy
This technical maintenance and content maintenance. Websites that are no longer being maintained should be archived. ... Perform ongoing content maintenance.. *Quarterly: Technical Maintenance. Complete the tasks listed under Technical Web ... Home » Websites & Digital Media » Web Maintenance Requirements Office of Energy Efficiency and Renewable Energy (EERE) offices ... Content maintenance is the process of reviewing and improving website content. EERE expects each office to do a content ...
Basic Car Maintenance Tips & Services Checklist
With car maintenance tips from Toyota, youll not only help your vehicle perform better, but you could save money too. See our ... What if you own your car? As an owner, required maintenance advice is always good to follow because maintenance can help extend ... Certain models require a different maintenance schedule as described in their Maintenance Guide. 24-hour Roadside Assistance is ... Remember, basic car maintenance can save you a ton of money and maintain your cars value in the long run. For that reason, ...
Site Maintenance - Cuba Message Board - TripAdvisor
... the TripAdvisor site will undergo some scheduled maintenance for approximately three hours. During that time, many features of ... A final reminder that the site will go to read only for maintenance work to be carried out in a few minutes time. ... Tonight at 7:00pm US Eastern Time, thats midnight UK time, the TripAdvisor site will undergo some scheduled maintenance for ... You will not be able to connect to Facebook during this maintenance period ...
UPDATE: Dawgprints Maintenance « Dawg Prints Alerts
Preventive Maintenance Maturity Matrix 2013 version
This maturity matrix focused on Preventive Maintenance is the most updated one anywhere. Some of the brig… ... Maintenance Planning and Scheduling... by Ricky Smith CMRP,... 4908 views * Maintenance Craft Skill Maturity Ma... by Ricky ... Best Practices in Maintenance Plann... by Ricky Smith CMRP,... 7535 views * Maintenance Planning and Scheduling... by Ricky ... Maintenance does all PM tasks. Maintenance does most inspections and lubrication tasks. Operations has only a few tasks on a ...
ISO - Maintenance agencies and registration authorities
Maintenance Agency. Union de normalisation de la mécanique. maison de la mécanique - 45 rue Louis Blanc. F-92400 Courbevoie. ... Maintenance Agency. Global Legal Entity Identifier Foundation (acting on behalf of SNV). GLEIF. St. Alban-Vorstadt 5, Postfach ... Maintenance Agency. American Society of Heating, Refrigerating and Air-Conditioning Engineers, Inc.. 1791 Tullie Circle NE. ... Maintenance Agency. American Society of Heating, Refrigerating and Air-Conditioning Engineers, Inc.. 1791 Tullie Circle NE. ...
Package maintenance guide - Fedora Project Wiki
The Heart of Bicycle Maintenance | TreeHugger
Marital Maintenance | Alaska: The Last Frontier
System maintenance | information science | Britannica.com
Most maintenance is to adjust the system to the organizations changing needs and to new equipment and other software, but ... in a process known as system maintenance. A large system will typically be used and maintained for some 5 to 10 years or even ... System maintenance. information science. THIS IS A DIRECTORY PAGE. Britannica does not currently have an article on this topic. ... Most maintenance is to adjust the system to the organizations changing needs and to new equipment and other software, but ...
PostgreSQL: Re: Implementing Incremental View Maintenance
Re: Implementing Incremental View Maintenance. From:. Tatsuo Ishii ,ishii(at)sraoss(dot)co(dot)jp,. ... View Maintenance (IVM). It is possible to apply to current latest master branch. ... Re: Implementing Incremental View Maintenance at 2020-05-08 05:08:50 from Andy Fan ... Re: Implementing Incremental View Maintenance at 2020-04-13 05:18:35 from Yugo NAGATA ...
François Dumont - profile mode maintenance patch
Predictive Maintenance with MATLAB - MATLAB & Simulink
Learn how you can develop predictive maintenance algorithms with MATLAB. See how to acquire and preprocess data, perform ... Section 1: Introduction to Predictive Maintenance with MATLAB. Learn how predictive maintenance differs from the strategies ... Predictive maintenance lets you monitor equipment health to avoid future failures during operation. It uses predictive ... This ebook will help you get started with predictive maintenance algorithm development with MATLAB® by explaining the ...
Maintenance préventive : Salesforce tran...
Channel Maintenance - Awasu Forums
Since Channel Maintenance is currently not working on your machine, what Im suggesting is that you send me your .CHANNEL files ... I cant open Channel Maintenance.exe...this is the message. Cant initialize. Cant find user directories or something ... adds them to the list of users shown by the Channel Maintenance and Awasu Admin programs.. InstallShield is a widely-used tool ...
Maintenance | Twente Graduate School
Maintenance is an essential part of daily life.. This is reflected in the economic importance that maintenance has: € 400 ... PDEng programme in Maintenance. The PDEng programme Maintenance educates technological designers who are capable to design ... Wold Class Maintenance ( Sabic, Sitech, Nedtrain, etc.)). More information and Contact. Would you like to know more about the ... In practice, maintenance is often carried out on the basis of empirical approaches and experiences from the past. As a result, ...
Maintenance - Wheaton College, IL
Archive of New and Changing Blog Posts about maintenance, published by Academic and Institutional Technology at Wheaton College ... During maintenance, there will be intermittent network disruption.. Read More Tags: Maintenance Network Network Unavailable ... Tags: Maintenance Network Network Unavailable During Maintenance. Posted March 2, 2017. by Academic and Institutional ... Tags: Maintenance Network Network Unavailable During Maintenance. Posted November 9, 2016. by Academic and Institutional ...
Reduce production downtime with faster maintenance - Office Support
Production downtime due to maintenance requests can cost businesses time and money. You need an easy way to track requests and ... With SharePoint, you have one place to store previous maintenance requests, with known processes, contacts, and procedures, so ... which makes it easy to track progress and balance resource needs for maintenance requests across the company. ...
NPS Essential Competencies: Accessibility: Maintenance First Line Supervisor
ICD - ICD-10-CM - Coordination and Maintenance Committee
Recording of the code topics discussed during the September 8th, 2020 ICD-10 Coordination and Maintenance Committee Meeting*: ... Recording of the code topics discussed during the September 8th, 2020 ICD-10 Coordination and Maintenance Committee Meeting*: ... Recording of the code topics discussed during the September 9th, 2020 ICD-10 Coordination and Maintenance Committee Meeting*: ... WebEx Recording of Wednesday March 18, 2020 Coordination and Maintenance Meetingexternal icon ...
ICD - ICD-10-CM - Coordination and Maintenance Committee
... co-chair the ICD-10 Coordination and Maintenance Committee meetings. Responsibility for maintenance of the ICD-10 is shared ... 2014 the ICD-9-CM Coordination and Maintenance Committee was renamed the ICD-10 Coordination and Maintenance Committee. A ... The ICD-9-CM Coordination and Maintenance Committee implemented a partial freeze of the ICD-9-CM and ICD-10 (ICD-10-CM and ICD- ... The ICD-10 Coordination and Maintenance Committee meetings are held on a virtual platform and open to the public. Access ...
XML Security Spec Maintenance WG -- 22 May 2007
tlr, The Reference Processing Model (section 126.96.36.199) requires that validators use Canonical XML 1.0 [XML-C14N] when a transformation that would expect an octet-stream as input is applied to a node-set. We RECOMMEND that generators do not rely on this default behavior, but explicitly identify the transformation that is applied to perform this mapping. In cases in which inclusive canonicalization is desired, we RECOMMEND that Canonical XML 1.1 [XML-C14N11] be used ...
Finding the maintenance products you need is easy with the SKF Maintenance and Lubrication Products online catalogue. This ... SKF maintenance products also help ensure greater safety for both machines and operators. Products include: *Pullers ... The SKF range of maintenance products has been carefully developed to help achieve maximum bearing service life. For more than ... Visit the online catalogue and start exploring our extensive range of maintenance products. ...
Maintenance | ASHE
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... Extending the bearing life cycle. The SKF range of maintenance products has been carefully developed to ... Search the SKF Maintenance Products catalogue online. Finding the maintenance products you need is easy with the SKF ... Services (Consultancy, Maintenance). Vehicle aftermarket. Distributor category *. All categories. SKF Authorized Distributor. ... Visit the online catalogue and start exploring our extensive range of maintenance products. ...
Every time a new appliance leaves a factory or a new car rolls off the line, a skilled industrial maintenance technician played ... Industrial maintenance technicians are needed in every industry that uses machinery, from automotive assembly plants to ... Industrial maintenance is divided into two distinct pathways, electrical and instrumentation and mechanical. ... http://testwww.alsde.edu/sec/cte/Pages/manufacturingfaqs-all.aspx?tab=Industrial Maintenance. ...
Rename a maintenance Use method maintenance.update, set "name":",new name," Retrieve maintenance details by Maintenance IDs Use ... Add a maintenance Use method maintenance.create Add a bunch of new maintenances Use method maintenance.create with array of ... Retrieve maintenance details by Maintenance name Use method maintenance.get with parameter filter, specify "name":",your ... maintenance_type. integer. Type. 0: With data collection. 1: No data collection. ...
Operations include pavement surface maintenance, pedestrian facility maintenance, street sweeping, maintenance of storm drain ... The Street Maintenance Section provides equipment and staffing for year-round preservation and maintenance of Municipal streets ... The Street Maintenance Section maintains 1,281 lane miles of Municipal roads and approximately 200 miles of sidewalks and ... The Street Maintenance Section is dedicated to preserving the communitys investment in Municipal roadways and providing its ...
Operations & Maintenance
CTS will perform all off-wing maintenance on the engines. According to the NK agreement, CTS will provide all on-wing engine ... CTS will perform all off-wing maintenance on the engines. According to the NK agreement, CTS will provide all on-wing engine ... CTS Engines has signed multi-year engine maintenance service agreements with Finnish cargo carrier Nordic Global Airlines (NGA ... CTS Engines has signed multi-year engine maintenance service agreements with Finnish cargo carrier Nordic Global Airlines (NGA ...
Scheduled Oil Sampling as A Maintenance Tool
Re: A workflow for local patch maintenance
Exercise: Grounds Maintenance Project - Neighborhood Averages · GitBook
GIS for Telecommunications I Network Operations & Maintenance
Optimizing network operations and maintenance is not only optimizing communication networks but also the people, processes, and ... Telecommunications: Network op & maintenance. Download the poster to learn more about Esris network operations and maintenance ... Telecommunications: Network op & maintenance Node capacity analysis Are your business processes a business constraint? ... Telecommunications: Network op & maintenance Node capacity analysis Are your business processes a business constraint? ...
sagora Maintenance Jobs in Burleson, Texas | Military
U.S. GAO - Research Analysis & Maintenance, Inc.
Research Analysis and Maintenance, Inc. (RAM), of El Paso, Texas, protests the issuance of an order, by the General Services ... Research Analysis and Maintenance, Inc. (RAM), of El Paso, Texas, protests the issuance of an order, by the General Services ... Support includes the setup, configuration, operation, troubleshooting, and maintenance of the JTF SOF [Joint Task Force Special ... and maintenance of the [JTF SOF s] servers and workstations, JTF NIPRNET LAN, and JTF SIPRNET LAN when deployed during exercise ...
BBB Business Profile | Michael's Building Maintenance & Repairs
Services: Personal Services, Home Care and Maintenance
Exercise: Grounds Maintenance Project - Data Reprojection · GitBook
Monitoring maintenance plans for Project Server 2010
Database maintenance plans for Project Server 2010 Monitoring maintenance plans for Project Server 2010 ... Some maintenance tasks, such as nightly backups or hourly transactional log backups, may have a significant effect on system ... Operationally, maintenance tasks must be monitored for success and duration, and system performance must be monitored to find ... A database maintenance plan is only as good as its integrity is preserved, which requires monitoring. ...
Fujitsu Services - Field Maintenance Services - Fujitsu Finland
In order to provide customers with the highest quality IT support and maintenance, Fujitsu employs over 800 experienced IT ... Fujitsu Services - Field Maintenance Services. IT support and maintenance. Mobile IT solutions for faster communication. ... In order to provide customers with the highest quality IT support and maintenance, Fujitsu employs over 800 experienced IT ... Download the Fujitsu Services - field maintenance services case study PDF (91 KB) [91 KB] ...
'Outstanding' Ovarian Cancer PFS With Olaparib...
Patients with newly diagnosed advanced ovarian cancer have a marked increase in progression-free survival with maintenance ... Taking over the podium, Moore said that SOLO1 is the first phase 3 trial to examine maintenance PARP inhibitor therapy ... "Looking at existing results in relapse with PARP inhibitor maintenance in all comers, we can anticipate excellent results for ... "Also, what is the best maintenance therapy? Standard first-line therapy in many countries is chemotherapy plus bevacizumab ...
Asset Maintenance, Reliability and Turnaround | Shell Global
Asset Maintenance, Reliability and Turnaround Engineers make critical decisions regarding Shells offshore and onshore ... Find a Job in Operations & Maintenance Operations and maintenance Find a Job in Sales & Marketing Sales and marketing Find a ... "Pipeline maintenance engineering involves the maintenance of all the underground pipelines that belong to the asset land. When ... Asset Maintenance, Reliability and Turnaround Asset Maintenance, Reliability and Turnaround Engineers make critical decisions ...
2020RepairsInspectionWorkPerformWorkersPredictivePreventive Maintenance2018Coordination and Maintenance CommitteeTechnicianOptimizeTechnicians2017OperationsServicesBicycle maintenanceGrounds maintenance project2016ReduceUnnecessaryCertification MaintenanceDowntimeProgrammeAlertsBackupsCommitteeSiteManagementRoutineWorkLogisticsUpdateProductsRepairOccurEquipmentCheckPerformanceCostInfrastructureProgramDownloadRegular maintenanceCommunity'sServiceIdentifyHealthCostsImproveDistinct
- International lifting and offshore services specialist Huisman has developed a new crane series for maintenance work on offshore wind turbines. (khl.com)
- This work develops an integrated model to help highway agencies in developing traffic control plans for maintenance activities and in efficiently managing traffic around highway work zones. (final-yearproject.com)
- This includes corresponding efforts at regular, systematic maintenance work. (thenextweb.com)
- Predictive maintenance helps you achieve a significant reduction in inventory. (microsoft.com)
- The Predictive Maintenance solution gives you better visibility into equipment status, letting you resolve issues before they disrupt your business. (microsoft.com)
- Unifies disparate operational data into analytics driven predictive maintenance models. (ibm.com)
- What is predictive maintenance? (ibm.com)
- Predictive maintenance is the asset management practice of repairing an asset or piece of equipment before it fails based on data received about it. (ibm.com)
- Predictive maintenance has emerged as a systems and software capability because more information has become available from assets themselves, and operational and maintenance functions have become digitized. (ibm.com)
- Why is predictive maintenance important? (ibm.com)
- These benefits are driving organizations to take advantage of predictive maintenance technologies and practices. (ibm.com)
- There, its customers use dashboards to track efficiency, create predictive maintenance plans and remotely monitor real-time status. (ibm.com)
- Effective predictive maintenance harnesses the convergence of data from instrumentation and IoT with advanced analytics and AI technologies through digitized systems. (ibm.com)
- Predictive maintenance lets you monitor equipment health to avoid future failures during operation. (mathworks.com)
- This ebook will help you get started with predictive maintenance algorithm development with MATLAB ® by explaining the terminology and providing access to examples, tutorials, and trial software. (mathworks.com)
- Learn how predictive maintenance differs from the strategies such as reactive and preventive maintenance. (mathworks.com)
- Walk through the predictive maintenance workflow steps such as acquiring and preprocessing data, feature extraction, and training machine learning models. (mathworks.com)
- Many forward-looking executives are turning to predictive maintenance (PM) solutions to help prevent equipment failures and avoid the costs of unplanned downtime. (sas.com)
- This paper explores the business case for investing in predictive maintenance solutions, examines how they work to lower maintenance costs and minimize disruptions across the enterprise, and describes what is required to get started with PM today. (sas.com)
- This solution helps you move beyond your preventive maintenance program to predict when your equipment needs to be serviced. (microsoft.com)
- Connecting products, monitoring performance, and predicting the deterioration of tools enables you to advance from traditional maintenance practices-like unplanned and preventive maintenance-to more modern, cost-effective practices. (microsoft.com)
- Transitioning from preventive maintenance to new digital capabilities offers you an opportunity to leverage condition monitoring tools for your equipment-at the lowest operational cost. (microsoft.com)
- Mechanical or electronic failures may occur from time to time in a complex system like a feed mill, but proper attention to preventive maintenance will minimize down time and the prospect of the customer receiving feed which is out of specification. (fao.org)
- A good preventive maintenance programme should provide adequate maintenance at reasonable cost (Appendix III). (fao.org)
- In Appendix IV a checklist is provided to highlight generalised preventive maintenance functions, which are to be checked periodically. (fao.org)
- This maturity matrix focused on Preventive Maintenance is the most updated one anywhere. (slideshare.net)
Coordination and Maintenance Committee7
- June 11, 2021 is the deadline for new proposals received to be discussed at the September 14-15, 2021 ICD-10 Coordination and Maintenance Committee Meeting. (cdc.gov)
- As of the March 19, 2014 the ICD-9-CM Coordination and Maintenance Committee was renamed the ICD-10 Coordination and Maintenance Committee. (cdc.gov)
- A representative from the National Center for Health Statistics (NCHS) and one from the Centers for Medicare and Medicaid Services (CMS) co-chair the ICD-10 Coordination and Maintenance Committee meetings. (cdc.gov)
- The ICD-10 Coordination and Maintenance Committee is a Federal interdepartmental committee. (cdc.gov)
- Once proposals are reviewed all requestors will be contacted as to whether the proposal has been approved for presentation at the ICD-10 Coordination and Maintenance Committee meeting or not. (cdc.gov)
- The ICD-10 Coordination and Maintenance Committee meetings are held on a virtual platform and open to the public. (cdc.gov)
- The ICD-9-CM Coordination and Maintenance Committee implemented a partial freeze of the ICD-9-CM and ICD-10 (ICD-10-CM and ICD-10-PCS) codes prior to the implementation of ICD-10. (cdc.gov)
- It allows maintenance managers to easily access information to determine which assets are being over-, under- or well-maintained and uses this prescriptive analysis to optimize maintenance practices and resources. (ibm.com)
- Without careful analysis of asset operational data and factors affecting asset performance it is difficult to determine the how to best allocate maintenance resources and schedules so as to optimize asset availability and reduce maintenance costs. (ibm.com)
- The overall goal of Aviation Maintenance human factors research is to identify and optimize the factors that affect human performance in maintenance and inspection. (faa.gov)
- This course is designed for maintenance technicians with BBJ experience who require an airplane systems review. (boeing.com)
- Offering planned and emergency commercial plumbers, electricians, air conditioning engineers, fire alarm and system technicians and building maintenance experts. (youtube.com)
- The new version of MicroMain Mobile is cleaner and easier to use than ever before, allowing maintenance technicians to more efficiently create, update, and close work orders on the go. (prweb.com)
- Industrial maintenance technicians are needed in every industry that uses machinery, from automotive assembly plants to computer manufacturers. (alsde.edu)
- From providing scheduled maintenance operations or upgrading an avionics system to trouble-shooting a mechanical issue or repainting a livery, we are committed to providing you best-in-class service. (boeing.com)
- Currently there is a large gap in maintenance approach between technical specialists and operations managers, originating from different perspectives on maintenance. (utwente.nl)
- Operations include pavement surface maintenance, pedestrian facility maintenance, street sweeping, maintenance of storm drain facilities and snow plowing and removal during the winter months. (muni.org)
- Optimizing network operations and maintenance is not only optimizing communication networks but also the people, processes, and systems that maintain and manage telecom networks. (esri.com)
- Download the poster to learn more about Esri's network operations and maintenance capabilities. (esri.com)
- How can ArcGIS help you in your network operations & maintenance efforts? (esri.com)
- Unlike fee-for-service medicine, HMOs (a 1970s term) are group practices, providing relatively comprehensive (primary and hospital) services for a standard prepayment, so helping to reduce costs and increasing medical incentives to health maintenance. (encyclopedia.com)
- Additionally, there are a handful of car maintenance services you shouldn't skip, Bank Rate said. (ajc.com)
- The Xtralifts are covered by Stannah's comprehensive 24/7 lift service plan, with 12 service visits in the first year, and continued lift maintenance by the London and South East Dartford branch of Stannah Lift Services, part of a nationwide network providing comprehensive lift servicing and support. (yudu.com)
- Due to system maintenance, the following services will be temporarily suspended. (jal.co.jp)
- Property management services have been taken to the next level with the launch of CMS Ltd professional and expert commercial property maintenance and management services in Newcastle and throughout the North East UK. (youtube.com)
- MicroMain , an industry leader in maintenance and facility management software and services, announces the release of an all-new version of MicroMain Mobile. (prweb.com)
- MicroMain Corporation provides award-winning facility management and preventative maintenance software and services to organizations worldwide. (prweb.com)
- Check your vehicle's owner's manual and find out when your recommended car maintenance services should be scheduled. (toyota.com)
- Scheduling maintenance services through your dealer may be best. (toyota.com)
- Salesforce ajoute IoT Insights en tant que composant de son produit Field Service Lightning, combinant des données IoT avec d'autres informations pour les opérateurs de services sur le terrain. (scoop.it)
- These competencies include the ability to integrate accessibility into the planning, development, and implementation of the total scope of maintenance projects and services. (nps.gov)
- By submitting a residence maintenance request you are giving residence services the right to enter you unit during maintenance business hours, 9 a.m. - 9 p.m. 7 days a week, to fix the problem. (ucalgary.ca)
Grounds maintenance project1
- Bouygues Telecom rapproche ses activités de M2M et de LoRaWAN pour la gestion des objets connectés sous la marque Objenious, sa filiale lancée en 2016. (scoop.it)
- High Maintenance originally premiered as a web series on Vimeo on November 11, 2012 and began airing as a television series on HBO on September 16, 2016. (wikipedia.org)
- Certification Maintenance strengthens the value of certification, demonstrating your ongoing commitment to excellence to elected officials, community leaders, and employers. (planning.org)
- The Certification Maintenance (CM) program links certified planners to training opportunities that keep them up to date on the latest trends, technologies, and best practices. (planning.org)
- The PDEng programme Maintenance educates technological designers who are capable to design efficient and effective maintenance processes from a multidisciplinary perspective. (utwente.nl)
- If you have any further questions about the PDEng programme in Maintenance, please contact programme director Prof.dr.ir. (utwente.nl)
- This allows you to create automatic alerts and actions, such as remote diagnostics, maintenance requests, and other workflows. (microsoft.com)
- The Aviation Maintenance Alerts provides a way to share information on aviation service experiences. (faa.gov)
- There are no maintenance alerts for this year. (faa.gov)
- Committee members can find more information about Maintenance Agencies in Annex G of the ISO/IEC Directives Part 1 . (iso.org)
- Deze site maakt gebruik van cookies om analyses te kunnen uitvoeren en persoonlijke inhoud en reclame te kunnen weergeven. (microsoft.com)
- Boeing provides on-site maintenance and support ensuring F/A-18 fleets (both Classic Hornets and Super Hornets) are mission ready. (boeing.com)
- Tonight at 7:00pm US Eastern Time, that's midnight UK time, the TripAdvisor site will undergo some scheduled maintenance for approximately three hours. (tripadvisor.co.uk)
- Just a reminder of the Site Maintenance tonight. (tripadvisor.co.uk)
- A final reminder that the site will go to read only for maintenance work to be carried out in a few minutes time. (tripadvisor.co.uk)
- Training of maintenance staff should be a high priority with high-level management oversight. (fao.org)
- MicroMain Mobile is an add-on application for use with MicroMain's award-winning maintenance management (CMMS) software, MicroMain Maintenance. (prweb.com)
- The solution developed by Fujitsu provides a powerful platform for supporting mobile applications across their lifecycle - from deployment and customisation through management, maintenance and updates. (fujitsu.com)
- Maintenance Logistics offers our service partners competent support for the entire IT spare part supply: procurement - planning - inventory management - warehousing - transport management - returns management - repair management - warranty handling. (fujitsu.com)
- The contract you make with your tenant should allow you access for any maintenance or safety check work that needs to be done. (hse.gov.uk)
- You may report housekeeping and maintenance concerns via a work order. (uwm.edu)
- Between work, family events, and the dozens of other obligations people have, basic car maintenance can fall by the wayside. (toyota.com)
- DeKalb County School District outsources some of its maintenance work to outside vendors, and officials said previously that was done to get more of the requests tackled. (ajc.com)
- For a design to comply with an integral maintenance-aware solution, technical, financial, logistics and organisational specifications need to be set and fulfilled. (utwente.nl)
- Fujitsu Technology Solutions Maintenance Logistics is responsible for controlling the entire spare part cycle - all done on a worldwide, environmentally friendly basis. (fujitsu.com)
- When major maintenance such as patching is performed, a backup is recommended as the first step in case the update fails and reversion is required. (wikipedia.org)
- With Mobile, users can update their maintenance database in real-time from anywhere using any Internet-enabled devise, including laptops, tablets, and smartphones. (prweb.com)
- This latest release of MicroMain Mobile coincides with an update to MicroMain's flagship CMMS solution, MicroMain Maintenance. (prweb.com)
- Since Channel Maintenance is currently not working on your machine, what I'm suggesting is that you send me your .CHANNEL files, I'll fix them up for you, then when you copy them back, the next time Awasu starts, your channels will have new update intervals. (awasu.com)
- Faulty maintenance can affect how you manage inventories, distribute products and goods, and handle supplier relationships. (microsoft.com)
- The SKF range of maintenance products has been carefully developed to help achieve maximum bearing service life. (skf.com)
- SKF maintenance products also help ensure greater safety for both machines and operators. (skf.com)
- Finding the maintenance products you need is easy with the SKF Maintenance and Lubrication Products online catalogue. (skf.com)
- Visit the online catalogue and start exploring our extensive range of maintenance products. (skf.com)
- Excludes "Maintenance and Repair Workers, General" (49-9071). (bls.gov)
- The agency's data showed that skipped maintenance caused literally millions of breakdowns each year and that consumers who don't keep up with maintenance ultimately pay higher repair costs. (ajc.com)
- The city's library presidents will make their case to the City Council this morning for increased funding and a boost in capital dollar spending to repair what they call a "maintenance crisis" across the city's 207 libraries. (politico.com)
- Common Cycle's bi-annual maintenance courses are intended to help train future volunteers and community members by providing hands on experience and general knowledge about fixing bicycles and assisting people who come to our mobile repair stand. (google.com)
- We cover a range of repair and maintenance from basic (e.g. tube change, brake adjustment) to advanced (e.g. hub overhaul, wheel truing). (google.com)
- Apply machine learning, using principles of math, science, and engineering to identify correlations between maintenance data and operating data along with any other data that may contain clues about equipment usage and degradation. (ibm.com)
- Careful attention should be paid to the equipment manufacturer s suggested maintenance schedule(s). (fao.org)
- The Street Maintenance Section provides equipment and staffing for year-round preservation and maintenance of Municipal streets. (muni.org)
- At the most granular level, maintenance personnel gain an understanding of individual drivers and factors that affect asset performance, as well as detailed attributes of the asset, predicted time to failure, and maintenance logs. (ibm.com)
- This level of detail can help a manager visually correlate factors that are positively and negatively influencing asset performance in context of historical failure data and maintenance and replacement activities. (ibm.com)
- Adequate space, ventilation and lighting shall be maintained for the proper performance of all manufacturing, storing, labelling, quality assurance and maintenance aspects of aquaculture feed manufacturing. (fao.org)
- also, that maintenance improvement and cost reduction may be difficult, but certainly is not unattainable. (sae.org)
- The plant maintenance program is vital to consistent production of high quality feeds and no less important to cost control and assurance to the customer that their feed will arrive on time and to formula specification (Parr, 1988). (fao.org)
- When adding additional licensed copies to your multi-user license, the maintenance cost for these additional copies will be prorated to match the maintenance expiration date of the original purchase. (pdfforge.org)
- This is reflected in the economic importance that maintenance has: € 400 billion of invested capital, annual cost of € 18 billion and more than 150,000 workplaces (in the Netherlands). (utwente.nl)
- Included in the report are examples of branch's maintenance needs along with a description of the community's profile outlining the local levels of education and the average household income. (politico.com)
- The Street Maintenance Section is dedicated to preserving the community's investment in Municipal roadways and providing its citizens with safe, clean streets. (muni.org)
- Maintenance from the meter to the service pipework (external to the property) is not the responsibility of the landlord but the pipeline operator (usually TRANSCO). (hse.gov.uk)
- But does keeping up with maintenance mean paying for every service under the sun? (ajc.com)
- comprehensive property surveys, mould removal treatment and a full installation service for both responsive and planned maintenance. (yudu.com)
- Dealers often put a sticker on your vehicle that includes a reminder of the date of your next maintenance service. (toyota.com)
- Going to the same Toyota dealer for maintenance means you'll have a complete service history for the vehicle. (toyota.com)
- Set a service procedure in motion with Project, which makes it easy to track progress and balance resource needs for maintenance requests across the company. (microsoft.com)
- CTS Engines has signed multi-year engine maintenance service agreements with Finnish cargo carrier Nordic Global Airlines (NGA), and Ft. Lauderdale, Fla.-based Spirit Airlines (NK). (atwonline.com)