Magnetic resonance spectroscopy. Medical search

Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).

Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.

An amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as CREATININE in the urine.

An endogenous substance found mainly in skeletal muscle of vertebrates. It has been tried in the treatment of cardiac disorders and has been added to cardioplegic solutions. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1996)

A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.

One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.

Stable elementary particles having the smallest known positive charge, found in the nuclei of all elements. The proton mass is less than that of a neutron. A proton is the nucleus of the light hydrogen atom, i.e., the hydrogen ion.

A technique applicable to the wide variety of substances which exhibit paramagnetism because of the magnetic moments of unpaired electrons. The spectra are useful for detection and identification, for determination of electron structure, for study of interactions between molecules, and for measurement of nuclear spins and moments. (From McGraw-Hill Encyclopedia of Science and Technology, 7th edition) Electron nuclear double resonance (ENDOR) spectroscopy is a variant of the technique which can give enhanced resolution. Electron spin resonance analysis can now be used in vivo, including imaging applications such as MAGNETIC RESONANCE IMAGING.

NMR spectroscopy on small- to medium-size biological macromolecules. This is often used for structural investigation of proteins and nucleic acids, and often involves more than one isotope.

A non-metal element that has the atomic symbol P, atomic number 15, and atomic weight 31. It is an essential element that takes part in a broad variety of biochemical reactions.

The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.

An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.

Stable phosphorus atoms that have the same atomic number as the element phosphorus, but differ in atomic weight. P-31 is a stable phosphorus isotope.

Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.

Stable carbon atoms that have the same atomic number as the element carbon, but differ in atomic weight. C-13 is a stable carbon isotope.

The chemical reactions involved in the production and utilization of various forms of energy in cells.

A nonmetallic, diatomic gas that is a trace element and member of the halogen family. It is used in dentistry as flouride (FLUORIDES) to prevent dental caries.

Inorganic salts of phosphoric acid.

A type of imaging technique used primarily in the field of cardiology. By coordinating the fast gradient-echo MRI sequence with retrospective ECG-gating, numerous short time frames evenly spaced in the cardiac cycle are produced. These images are laced together in a cinematic display so that wall motion of the ventricles, valve motion, and blood flow patterns in the heart and great vessels can be visualized.

A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells.

The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)

Changes in the amounts of various chemicals (neurotransmitters, receptors, enzymes, and other metabolites) specific to the area of the central nervous system contained within the head. These are monitored over time, during sensory stimulation, or under different disease states.

A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)

A non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.

A noninvasive technique that uses the differential absorption properties of hemoglobin and myoglobin to evaluate tissue oxygenation and indirectly can measure regional hemodynamics and blood flow. Near-infrared light (NIR) can propagate through tissues and at particular wavelengths is differentially absorbed by oxygenated vs. deoxygenated forms of hemoglobin and myoglobin. Illumination of intact tissue with NIR allows qualitative assessment of changes in the tissue concentration of these molecules. The analysis is also used to determine body composition.

A diagnostic technique that incorporates the measurement of molecular diffusion (such as water or metabolites) for tissue assessment by MRI. The degree of molecular movement can be measured by changes of apparent diffusion coefficient (ADC) with time, as reflected by tissue microstructure. Diffusion MRI has been used to study BRAIN ISCHEMIA and tumor response to treatment.

The measurement of the amplitude of the components of a complex waveform throughout the frequency range of the waveform. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)

Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.

The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).

Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.

An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.

Substances used to allow enhanced visualization of tissues.

The first chemical element in the periodic table. It has the atomic symbol H, atomic number 1, and atomic weight [1.00784; 1.00811]. It exists, under normal conditions, as a colorless, odorless, tasteless, diatomic gas. Hydrogen ions are PROTONS. Besides the common H1 isotope, hydrogen exists as the stable isotope DEUTERIUM and the unstable, radioactive isotope TRITIUM.

Spectrophotometry in the infrared region, usually for the purpose of chemical analysis through measurement of absorption spectra associated with rotational and vibrational energy levels of molecules. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.

The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.

A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.

A biosensing technique in which biomolecules capable of binding to specific analytes or ligands are first immobilized on one side of a metallic film. Light is then focused on the opposite side of the film to excite the surface plasmons, that is, the oscillations of free electrons propagating along the film's surface. The refractive index of light reflecting off this surface is measured. When the immobilized biomolecules are bound by their ligands, an alteration in surface plasmons on the opposite side of the film is created which is directly proportional to the change in bound, or adsorbed, mass. Binding is measured by changes in the refractive index. The technique is used to study biomolecular interactions, such as antigen-antibody binding.

An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.

The homogeneous mixtures formed by the mixing of a solid, liquid, or gaseous substance (solute) with a liquid (the solvent), from which the dissolved substances can be recovered by physical processes. (From Grant & Hackh's Chemical Dictionary, 5th ed)

Deuterium. The stable isotope of hydrogen. It has one neutron and one proton in the nucleus.

Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.

An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers.

A component of PHOSPHATIDYLCHOLINES or LECITHINS, in which the two hydroxy groups of GLYCEROL are esterified with fatty acids. (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules.

Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.

Salts or esters of LACTIC ACID containing the general formula CH3CHOHCOOR.

Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

The systematic identification and quantitation of all the metabolic products of a cell, tissue, organ, or organism under varying conditions. The METABOLOME of a cell or organism is a dynamic collection of metabolites which represent its net response to current conditions.

The sequence of carbohydrates within POLYSACCHARIDES; GLYCOPROTEINS; and GLYCOLIPIDS.

Molecules which contain an atom or a group of atoms exhibiting an unpaired electron spin that can be detected by electron spin resonance spectroscopy and can be bonded to another molecule. (McGraw-Hill Dictionary of Chemical and Technical Terms, 4th ed)

Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.

The rate dynamics in chemical or physical systems.

Elements of limited time intervals, contributing to particular results or situations.

The level of protein structure in which regular hydrogen-bond interactions within contiguous stretches of polypeptide chain give rise to alpha helices, beta strands (which align to form beta sheets) or other types of coils. This is the first folding level of protein conformation.

A change from planar to elliptic polarization when an initially plane-polarized light wave traverses an optically active medium. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.

One of the convolutions on the medial surface of the CEREBRAL HEMISPHERES. It surrounds the rostral part of the brain and CORPUS CALLOSUM and forms part of the LIMBIC SYSTEM.

Analysis of the intensity of Raman scattering of monochromatic light as a function of frequency of the scattered light.

A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.

Posterior portion of the CEREBRAL HEMISPHERES responsible for processing visual sensory information. It is located posterior to the parieto-occipital sulcus and extends to the preoccipital notch.

The study of the composition, chemical structures, and chemical reactions of the NERVOUS SYSTEM or its components.

A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see PENTETIC ACID), that is given to enhance the image in cranial and spinal MRIs. (From Martindale, The Extra Pharmacopoeia, 30th ed, p706)

The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.

The characteristic three-dimensional shape of a molecule.

A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).

The characteristic 3-dimensional shape of a carbohydrate.

Gadolinium. An element of the rare earth family of metals. It has the atomic symbol Gd, atomic number 64, and atomic weight 157.25. Its oxide is used in the control rods of some nuclear reactors.

A basic science concerned with the composition, structure, and properties of matter; and the reactions that occur between substances and the associated energy exchange.

The dynamic collection of metabolites which represent a cell's or organism's net metabolic response to current conditions.

Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.

The composition, conformation, and properties of atoms and molecules, and their reaction and interaction processes.

The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.

A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.

The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.

The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.

The part of the cerebral hemisphere anterior to the central sulcus, and anterior and superior to the lateral sulcus.

Methods developed to aid in the interpretation of ultrasound, radiographic images, etc., for diagnosis of disease.

A mass spectrometric technique that is used for the analysis of a wide range of biomolecules, such as glycoalkaloids, glycoproteins, polysaccharides, and peptides. Positive and negative fast atom bombardment spectra are recorded on a mass spectrometer fitted with an atom gun with xenon as the customary beam. The mass spectra obtained contain molecular weight recognition as well as sequence information.

Stable nitrogen atoms that have the same atomic number as the element nitrogen, but differ in atomic weight. N-15 is a stable nitrogen isotope.

The parts of a macromolecule that directly participate in its specific combination with another molecule.

Improvement of the quality of a picture by various techniques, including computer processing, digital filtering, echocardiographic techniques, light and ultrastructural MICROSCOPY, fluorescence spectrometry and microscopy, scintigraphy, and in vitro image processing at the molecular level.

A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.

A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.

The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.

A metabolic process that converts GLUCOSE into two molecules of PYRUVIC ACID through a series of enzymatic reactions. Energy generated by this process is conserved in two molecules of ATP. Glycolysis is the universal catabolic pathway for glucose, free glucose, or glucose derived from complex CARBOHYDRATES, such as GLYCOGEN and STARCH.

The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.

Analysis based on the mathematical function first formulated by Jean-Baptiste-Joseph Fourier in 1807. The function, known as the Fourier transform, describes the sinusoidal pattern of any fluctuating pattern in the physical world in terms of its amplitude and its phase. It has broad applications in biomedicine, e.g., analysis of the x-ray crystallography data pivotal in identifying the double helical nature of DNA and in analysis of other molecules, including viruses, and the modified back-projection algorithm universally used in computerized tomography imaging, etc. (From Segen, The Dictionary of Modern Medicine, 1992)

Measurement of the intensity and quality of fluorescence.

Chromatography on thin layers of adsorbents rather than in columns. The adsorbent can be alumina, silica gel, silicates, charcoals, or cellulose. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

The isotopic compound of hydrogen of mass 2 (deuterium) with oxygen. (From Grant & Hackh's Chemical Dictionary, 5th ed) It is used to study mechanisms and rates of chemical or nuclear reactions, as well as biological processes.

Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.

The thin layer of GRAY MATTER on the surface of the CEREBRAL HEMISPHERES that develops from the TELENCEPHALON and folds into gyri and sulchi. It reaches its highest development in humans and is responsible for intellectual faculties and higher mental functions.

A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed)

In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.

The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.

An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)

The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)

Methods for visualizing REGIONAL BLOOD FLOW, metabolic, electrical, or other physiological activities in the CENTRAL NERVOUS SYSTEM using various imaging modalities.

A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.

Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

A rigorously mathematical analysis of energy relationships (heat, work, temperature, and equilibrium). It describes systems whose states are determined by thermal parameters, such as temperature, in addition to mechanical and electromagnetic parameters. (From Hawley's Condensed Chemical Dictionary, 12th ed)

Mitochondria of skeletal and smooth muscle. It does not include myocardial mitochondria for which MITOCHONDRIA, HEART is available.

Derivatives of ACETIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxymethane structure.

Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.

A conjugated protein which is the oxygen-transporting pigment of muscle. It is made up of one globin polypeptide chain and one heme group.

Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.

A methylpentose whose L- isomer is found naturally in many plant glycosides and some gram-negative bacterial lipopolysaccharides.

Physiological processes in biosynthesis (anabolism) and degradation (catabolism) of LIPIDS.

A type of FLUORESCENCE SPECTROSCOPY using two FLUORESCENT DYES with overlapping emission and absorption spectra, which is used to indicate proximity of labeled molecules. This technique is useful for studying interactions of molecules and PROTEIN FOLDING.

Particles consisting of aggregates of molecules held loosely together by secondary bonds. The surface of micelles are usually comprised of amphiphatic compounds that are oriented in a way that minimizes the energy of interaction between the micelle and its environment. Liquids that contain large numbers of suspended micelles are referred to as EMULSIONS.

The rostral part of the frontal lobe, bounded by the inferior precentral fissure in humans, which receives projection fibers from the MEDIODORSAL NUCLEUS OF THE THALAMUS. The prefrontal cortex receives afferent fibers from numerous structures of the DIENCEPHALON; MESENCEPHALON; and LIMBIC SYSTEM as well as cortical afferents of visual, auditory, and somatic origin.

A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.

Lipids containing one or more phosphate groups, particularly those derived from either glycerol (phosphoglycerides see GLYCEROPHOSPHOLIPIDS) or sphingosine (SPHINGOLIPIDS). They are polar lipids that are of great importance for the structure and function of cell membranes and are the most abundant of membrane lipids, although not stored in large amounts in the system.

Any visible result of a procedure which is caused by the procedure itself and not by the entity being analyzed. Common examples include histological structures introduced by tissue processing, radiographic images of structures that are not naturally present in living tissue, and products of chemical reactions that occur during analysis.

Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure.

Inorganic compounds that contain phosphorus as an integral part of the molecule.

Determination of the spectra of ultraviolet absorption by specific molecules in gases or liquids, for example Cl2, SO2, NO2, CS2, ozone, mercury vapor, and various unsaturated compounds. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

Tomography using x-ray transmission and a computer algorithm to reconstruct the image.

Acquired or inborn metabolic diseases that produce brain dysfunction or damage. These include primary (i.e., disorders intrinsic to the brain) and secondary (i.e., extracranial) metabolic conditions that adversely affect cerebral function.

A microanalytical technique combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determinations of compounds.

Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins.

The most common inhibitory neurotransmitter in the central nervous system.

A low-energy attractive force between hydrogen and another element. It plays a major role in determining the properties of water, proteins, and other compounds.

Devices or objects in various imaging techniques used to visualize or enhance visualization by simulating conditions encountered in the procedure. Phantoms are used very often in procedures employing or measuring x-irradiation or radioactive material to evaluate performance. Phantoms often have properties similar to human tissue. Water demonstrates absorbing properties similar to normal tissue, hence water-filled phantoms are used to map radiation levels. Phantoms are used also as teaching aids to simulate real conditions with x-ray or ultrasonic machines. (From Iturralde, Dictionary and Handbook of Nuclear Medicine and Clinical Imaging, 1990)

The white of an egg, especially a chicken's egg, used in cooking. It contains albumin. (Random House Unabridged Dictionary, 2d ed)

Minimally invasive procedures guided with the aid of magnetic resonance imaging to visualize tissue structures.

Layers of lipid molecules which are two molecules thick. Bilayer systems are frequently studied as models of biological membranes.

Lower lateral part of the cerebral hemisphere responsible for auditory, olfactory, and semantic processing. It is located inferior to the lateral fissure and anterior to the OCCIPITAL LOBE.

Paired bodies containing mostly GRAY MATTER and forming part of the lateral wall of the THIRD VENTRICLE of the brain.

Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury.

An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.

An enzyme that is active in the first step of choline phosphoglyceride (lecithin) biosynthesis by catalyzing the phosphorylation of choline to phosphorylcholine in the presence of ATP. Ethanolamine and its methyl and ethyl derivatives can also act as acceptors. EC 2.7.1.32.

A series of oxidative reactions in the breakdown of acetyl units derived from GLUCOSE; FATTY ACIDS; or AMINO ACIDS by means of tricarboxylic acid intermediates. The end products are CARBON DIOXIDE, water, and energy in the form of phosphate bonds.

Mathematical procedure that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components.

A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.

Any visual display of structural or functional patterns of organs or tissues for diagnostic evaluation. It includes measuring physiologic and metabolic responses to physical and chemical stimuli, as well as ultramicroscopy.

The tendency of a gas or solute to pass from a point of higher pressure or concentration to a point of lower pressure or concentration and to distribute itself throughout the available space. Diffusion, especially FACILITATED DIFFUSION, is a major mechanism of BIOLOGICAL TRANSPORT.

Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.

Behavioral manifestations of cerebral dominance in which there is preferential use and superior functioning of either the left or the right side, as in the preferred use of the right hand or right foot.

A principle of estimation in which the estimates of a set of parameters in a statistical model are those quantities minimizing the sum of squared differences between the observed values of a dependent variable and the values predicted by the model.

A compound formed by the combination of hemoglobin and oxygen. It is a complex in which the oxygen is bound directly to the iron without causing a change from the ferrous to the ferric state.

The art or process of comparing photometrically the relative intensities of the light in different parts of the spectrum.

A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.

Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.

Non-fatal immersion or submersion in water. The subject is resuscitable.

2-(2,2-Dicyclohexylethyl)piperidine. Coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.

Relating to the size of solids.

Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated.

A class of compounds of the type R-M, where a C atom is joined directly to any other element except H, C, N, O, F, Cl, Br, I, or At. (Grant & Hackh's Chemical Dictionary, 5th ed)

Carbohydrates consisting of between two (DISACCHARIDES) and ten MONOSACCHARIDES connected by either an alpha- or beta-glycosidic link. They are found throughout nature in both the free and bound form.

Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.

A conditionally essential nutrient, important during mammalian development. It is present in milk but is isolated mostly from ox bile and strongly conjugates bile acids.

Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are linear polypeptides that are normally synthesized on RIBOSOMES.

Non-invasive methods of visualizing the CENTRAL NERVOUS SYSTEM, especially the brain, by various imaging modalities.

A circumscribed collection of purulent exudate in the brain, due to bacterial and other infections. The majority are caused by spread of infected material from a focus of suppuration elsewhere in the body, notably the PARANASAL SINUSES, middle ear (see EAR, MIDDLE); HEART (see also ENDOCARDITIS, BACTERIAL), and LUNG. Penetrating CRANIOCEREBRAL TRAUMA and NEUROSURGICAL PROCEDURES may also be associated with this condition. Clinical manifestations include HEADACHE; SEIZURES; focal neurologic deficits; and alterations of consciousness. (Adams et al., Principles of Neurology, 6th ed, pp712-6)

The circulation of blood through the BLOOD VESSELS of the BRAIN.

A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.

An imaging technique using compounds labelled with short-lived positron-emitting radionuclides (such as carbon-11, nitrogen-13, oxygen-15 and fluorine-18) to measure cell metabolism. It has been useful in study of soft tissues such as CANCER; CARDIOVASCULAR SYSTEM; and brain. SINGLE-PHOTON EMISSION-COMPUTED TOMOGRAPHY is closely related to positron emission tomography, but uses isotopes with longer half-lives and resolution is lower.

Differential thermal analysis in which the sample compartment of the apparatus is a differential calorimeter, allowing an exact measure of the heat of transition independent of the specific heat, thermal conductivity, and other variables of the sample.

Computer-assisted processing of electric, ultrasonic, or electronic signals to interpret function and activity.

Large subcortical nuclear masses derived from the telencephalon and located in the basal regions of the cerebral hemispheres.

The study of PHYSICAL PHENOMENA and PHYSICAL PROCESSES as applied to living things.

Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.

Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.

Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.

The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.

Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.

Processes involved in the formation of TERTIARY PROTEIN STRUCTURE.

A relatively common neoplasm of the CENTRAL NERVOUS SYSTEM that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and SPINAL CANAL. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7)

A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.

Lipids, predominantly phospholipids, cholesterol and small amounts of glycolipids found in membranes including cellular and intracellular membranes. These lipids may be arranged in bilayers in the membranes with integral proteins between the layers and peripheral proteins attached to the outside. Membrane lipids are required for active transport, several enzymatic activities and membrane formation.

Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.

Derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to a choline moiety. Complete hydrolysis yields 1 mole of glycerol, phosphoric acid and choline and 2 moles of fatty acids.

Upper central part of the cerebral hemisphere. It is located posterior to central sulcus, anterior to the OCCIPITAL LOBE, and superior to the TEMPORAL LOBES.

Computer-based representation of physical systems and phenomena such as chemical processes.

Non-invasive diagnostic technique for visualizing the PANCREATIC DUCTS and BILE DUCTS without the use of injected CONTRAST MEDIA or x-ray. MRI scans provide excellent sensitivity for duct dilatation, biliary stricture, and intraductal abnormalities.

Analysis of the energy absorbed across a spectrum of x-ray energies/wavelengths to determine the chemical structure and electronic states of the absorbing medium.

The physical characteristics and processes of biological systems.

Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Electron transfer through the cytochrome system liberating free energy which is transformed into high-energy phosphate bonds.

A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Carbon-containing phosphoric acid derivatives. Included under this heading are compounds that have CARBON atoms bound to one or more OXYGEN atoms of the P(=O)(O)3 structure. Note that several specific classes of endogenous phosphorus-containing compounds such as NUCLEOTIDES; PHOSPHOLIPIDS; and PHOSPHOPROTEINS are listed elsewhere.

Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.

An essential amino acid that is required for the production of HISTAMINE.

The science and art of collecting, summarizing, and analyzing data that are subject to random variation. The term is also applied to the data themselves and to the summarization of the data.

Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.

The largest and most lateral of the BASAL GANGLIA lying between the lateral medullary lamina of the GLOBUS PALLIDUS and the EXTERNAL CAPSULE. It is part of the neostriatum and forms part of the LENTIFORM NUCLEUS along with the GLOBUS PALLIDUS.

Treatment process involving the injection of fluid into an organ or tissue.

A physical property showing different values in relation to the direction in or along which the measurement is made. The physical property may be with regard to thermal or electric conductivity or light refraction. In crystallography, it describes crystals whose index of refraction varies with the direction of the incident light. It is also called acolotropy and colotropy. The opposite of anisotropy is isotropy wherein the same values characterize the object when measured along axes in all directions.

Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.

Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.

Addition of methyl groups. In histo-chemistry methylation is used to esterify carboxyl groups and remove sulfate groups by treating tissue sections with hot methanol in the presence of hydrochloric acid. (From Stedman, 25th ed)

Maintenance of a constant blood glucose level by perfusion or infusion with glucose or insulin. It is used for the study of metabolic rates (e.g., in glucose, lipid, amino acid metabolism) at constant glucose concentration.

An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)

Proteins found in any species of bacterium.

Fluids composed mainly of water found within the body.

The interaction of rhodium(II) carboxylates with enzymes. (1/24698)

The effect of rhodium(II) acetate, propionate, and methoxyacetate on the activity of 17 enzymes was evaluated. The enzymes were preincubated with the rhodium(II) complexes in order to detect irreversible inhibition. All enzymes that have essential sulfhydryl groups in or near their active site were found to be irreversibly inhibited. Those enzymes without essential sulfhydryl groups were not affected. In each case, the rate of inactivation closely paralleled the observed toxicity and antitumor activity of rhodium(II) carboxylates; that is, rhodium(II) propionate greater than rhodium(II) acetate greater than rhodium(II) methoxyacetate. In addition, those enzymes that have been demonstrated to be most sensitive to established sulfhydryl inhibitors, such as glyceraldehyde-3-phosphate dehydrogenase, were also most sensitive to rhodium(II) carboxylate inactivation. Proton nuclear magnetic resonance measurements made during the titration of rhodium(II) acetate with cysteine showed that breakdown of the carboxylate cage occurred as a result of reaction with this sulfhydryl-containing amino acid. (+info)

Prodigious substrate specificity of AAC(6')-APH(2"), an aminoglycoside antibiotic resistance determinant in enterococci and staphylococci. (2/24698)

BACKGROUND: High-level gentamicin resistance in enterococci and staphylococci is conferred by AAC(6')-APH(2"), an enzyme with 6'-N-acetyltransferase and 2"-O-phosphotransferase activities. The presence of this enzyme in pathogenic gram-positive bacteria prevents the successful use of gentamicin C and most other aminoglycosides as therapeutic agents. RESULTS: In an effort to understand the mechanism of aminoglycoside modification, we expressed AAC(6')-APH(2") in Bacillus subtilis. The purified enzyme is monomeric with a molecular mass of 57 kDa and displays both the expected aminoglycoside N-acetyltransferase and O-phosphotransferase activities. Structure-function analysis with various aminoglycosides substrates reveals an enzyme with broad specificity in both enzymatic activities, accounting for AAC(6')-APH(2")'s dramatic negative impact on clinical aminoglycoside therapy. Both lividomycin A and paromomycin, aminoglycosides lacking a 6'-amino group, were acetylated by AAC(6')-APH(2"). The infrared spectrum of the product of paromomycin acetylation yielded a signal consistent with O-acetylation. Mass spectral and nuclear magnetic resonance analysis of the products of neomycin phosphorylation indicated that phosphoryl transfer occurred primarily at the 3'-OH of the 6-aminohexose ring A, and that some diphosphorylated material was also present with phosphates at the 3'-OH and the 3"'-OH of ring D, both unprecedented observations for this enzyme. Furthermore, the phosphorylation site of lividomycin A was determined to be the 5"-OH of the pentose ring C. CONCLUSIONS: The bifunctional AAC(6')-APH(2") has the capacity to inactivate virtually all clinically important aminoglycosides through N- and O-acetylation and phosphorylation of hydroxyl groups. The extremely broad substrate specificity of this enzyme will impact on future development of aminoglycosides and presents a significant challenge for antibiotic design. (+info)

Single atom modification (O-->S) of tRNA confers ribosome binding. (3/24698)

Escherichia coli tRNALysSUU, as well as human tRNALys3SUU, has 2-thiouridine derivatives at wobble position 34 (s2U*34). Unlike the native tRNALysSUU, the full-length, unmodified transcript of human tRNALys3UUU and the unmodified tRNALys3UUU anticodon stem/loop (ASLLys3UUU) did not bind AAA- or AAG-programmed ribosomes. In contrast, the completely unmodified yeast tRNAPhe anticodon stem/loop (ASLPheGAA) had an affinity (Kd = 136+/-49 nM) similar to that of native yeast tRNAPheGmAA (Kd = 103+/-19 nM). We have found that the single, site-specific substitution of s2U34 for U34 to produce the modified ASLLysSUU was sufficient to restore ribosomal binding. The modified ASLLysSUU bound the ribosome with an affinity (Kd = 176+/-62 nM) comparable to that of native tRNALysSUU (Kd = 70+/-7 nM). Furthermore, in binding to the ribosome, the modified ASLLys3SUU produced the same 16S P-site tRNA footprint as did native E. coli tRNALysSUU, yeast tRNAPheGmAA, and the unmodified ASLPheGAA. The unmodified ASLLys3UUU had no footprint at all. Investigations of thermal stability and structure monitored by UV spectroscopy and NMR showed that the dynamic conformation of the loop of modified ASLLys3SUU was different from that of the unmodified ASLLysUUU, whereas the stems were isomorphous. Based on these and other data, we conclude that s2U34 in tRNALysSUU and in other s2U34-containing tRNAs is critical for generating an anticodon conformation that leads to effective codon interaction in all organisms. This is the first example of a single atom substitution (U34-->s2U34) that confers the property of ribosomal binding on an otherwise inactive tRNA. (+info)

Molecular dynamics studies of U1A-RNA complexes. (4/24698)

The U1A protein binds to a hairpin RNA and an internal-loop RNA with picomolar affinities. To probe the molecular basis of U1A binding, we performed state-of-the-art nanosecond molecular dynamics simulations on both complexes. The good agreement with experimental structures supports the protocols used in the simulations. We compare the dynamics, hydrogen-bonding occupancies, and interfacial flexibility of both complexes and also describe a rigid-body motion in the U1A-internal loop complex that is not observed in the U1A-hairpin simulation. We relate these observations to experimental mutational studies and highlight their significance in U1A binding affinity and specificity. (+info)

An examination of coaxial stacking of helical stems in a pseudoknot motif: the gene 32 messenger RNA pseudoknot of bacteriophage T2. (5/24698)

The RNA pseudoknot located at the 5' end of the gene 32 messenger RNA of bacteriophage T2 contains two A-form helical stems connected by two loops, in an H-type pseudoknot topology. A combination of multidimensional NMR methods and isotope labeling were used to investigate the pseudoknot structure, resulting in a more detailed structural model than provided by earlier homonuclear NMR studies. Of particular significance, the interface between the stacked helical stems within the pseudoknot motif is described in detail. The two stems are stacked in a coaxial manner, with an approximately 18 degrees rotation of stem1 relative to stem2 about an axis that is parallel to the helical axis. This rotation serves to relieve what would otherwise be a relatively close phosphate-phosphate contact at the junction of the two stems, while preserving the stabilizing effects of base stacking. The ability of the NMR data to determine pseudoknot bending was critically assessed. The data were found to be a modestly precise indicator of pseudoknot bending, with the angle between the helical axes of stem1 and stem2 being in the range of 15+/-15 degrees. Pseudoknot models with bend angles within this range are equally consistent with the data, since they differ by only small amounts in the relatively short-range interproton distances from which the structure was derived. The gene 32 messenger RNA pseudoknot was compared with other RNA structures with coaxial or near-coaxial stacked helical stems. (+info)

Purinogen is not an endogenous substrate used in endothelial cells during substrate deprivation. (6/24698)

Porcine aortic endothelial cells (PAEC) are known to be metabolically robust. They are capable of surviving extended periods of complete lack of exogenous substrate, and purine release has been shown to be significantly up-regulated. The endogenous substrates used during substrate deprivation, as well as the sources responsible for the increased purine release, have not been completely identified. We tested the possibility that a phosphoglyceroyl-ATP-containing polymer, purinogen, might support PAEC hibernation induced by lack of exogenous substrate. This involved isolation of the acid-insoluble fraction of PAEC, which was presumed to contain purinogen, and analysis by HPLC and 31P NMR. No evidence supporting the presence of triphosphate-containing compounds (purinogen) was found. Similar results were obtained in the rat heart. The majority of the products in the acid-insoluble, alkaline-treated fraction were identified as RNA degradation products (2'- and 3'-nucleoside monophosphates). A [14C]adenosine labelling experiment showed that incorporation of adenosine into the acid-insoluble fraction was almost completely prevented after inhibition of RNA synthesis with actinomycin D. Furthermore, RNA isolated from PAEC and subsequently treated with alkali showed a profile that was almost identical with the HPLC profile of the acid-insoluble fraction. Finally, substrate-free incubation of the cells did not quantitatively or qualitatively influence the distribution of acid-insoluble derivatives. We conclude that PAEC survival during the absence of exogenous substrate is not supported by purinogen but rather by some other, yet-to-be-identified, endogenous substrate. (+info)

Accumulation of astaxanthin all-E, 9Z and 13Z geometrical isomers and 3 and 3' RS optical isomers in rainbow trout (Oncorhynchus mykiss) is selective. (7/24698)

Concentrations of all-E-, 9Z- and 13Z- geometrical and (3R,3'R), (3R, 3'S) and (3S,3'S) optical isomers of astaxanthin were determined in rainbow trout liver, gut tissues, kidney, skin and blood plasma to evaluate their body distribution. Two cold-pelleted diets containing predominantly all-E-astaxanthin (36.9 mg/kg astaxanthin, 97% all-E-, 0.4% 9Z-, 1.5% 13Z-astaxanthin, and 1.1% other isomers, respectively) or a mixture of all-E- and Z-astaxanthins (35.4 mg/kg astaxanthin, 64% all-E-, 18.7% 9Z-, 12.3% 13Z-astaxanthin, and 2.0% other isomers, respectively), were fed to duplicate groups of trout for 69 d. Individual E/Z isomers were identified by VIS- and 1H-NMR-spectrometry, and quantified by high-performance liquid chromatography. Significantly higher total carotenoid concentration was observed in plasma of trout fed diets with all-E-astaxanthin (P < 0.05). The relative E/Z-isomer concentrations of plasma, skin and kidney were not significantly different among groups, whereas all-E-astaxanthin was higher in intestinal tissues and 13Z-astaxanthin was lower in liver of trout fed all-E-astaxanthin (P < 0.05). The relative amount of hepatic 13Z-astaxanthin (39-49% of total astaxanthin) was higher than in all other samples (P < 0.05). Synthetic, optically inactive astaxanthin was used in all experiments, and the determined dietary ratio between the 3R,3'R:3R, 3'S (meso):3S,3'S optical isomers was 25.3:49.6:25.1. The distribution of R/S-astaxanthin isomers in feces, blood, liver and fillet was similar to that in the diets. The ratio between (3S,3'S)- and (3R,3'R)-astaxanthin in the skin and posterior kidney was ca. 2:1 and 3:1, respectively, regardless of dietary E/Z-astaxanthin composition. The results show that geometrical and optical isomers of astaxanthin are distributed selectively in different tissues of rainbow trout. (+info)

Biophysical characterization of the structure of the amino-terminal region of gp41 of HIV-1. Implications on viral fusion mechanism. (8/24698)

A peptide of 51 amino acids corresponding to the NH2-terminal region (5-55) of the glycoprotein gp41 of human immunodeficiency virus type 1 was synthesized to study its conformation and assembly. Nuclear magnetic resonance experiments indicated the sequence NH2-terminal to the leucine zipper-like domain of gp41 was induced into helix in the micellar solution, in agreement with circular dichroism data. Light scattering experiment showed that the peptide molecules self-assembled in water into trimeric structure on average. That the peptide molecules oligomerize in aqueous solution was supported by gel filtration and diffusion coefficient experiments. Molecular dynamics simulation based on the NMR data revealed a flexible region adjacent to the hydrophobic NH2 terminus of gp41. The biological significance of the present findings on the conformational flexibility and the propensity of oligomerization of the peptide may be envisioned by a proposed model for the interaction of gp41 with membranes during fusion process. (+info)

... , most commonly known as NMR spectroscopy or magnetic resonance spectroscopy (MRS), is a ... vivo magnetic resonance spectroscopy Functional magnetic resonance spectroscopy of the brain Low field NMR Magnetic Resonance ... induction spectroscopy Triple-resonance nuclear magnetic resonance spectroscopy Zero field NMR Nuclear magnetic resonance ... Nuclear magnetic resonance spectroscopy, Nuclear magnetic resonance, Nuclear chemistry, Nuclear physics). ...

https://en.wikipedia.org/wiki/Nuclear_magnetic_resonance_spectroscopy

1H magnetic resonance spectroscopy of the prostate]" [1H magnetic resonance spectroscopy of the prostate]. Der Radiologe (in ... Magnetic resonance spectroscopy (MRS), also known as nuclear magnetic resonance (NMR) spectroscopy, is a non-invasive, ionizing ... In vivo magnetic resonance spectroscopy (MRS) is a specialized technique associated with magnetic resonance imaging (MRI). ... Functional magnetic resonance spectroscopy of the brain Magnetic resonance imaging Magnetization transfer NMR NMR spectroscopy ...

https://en.wikipedia.org/wiki/In_vivo_magnetic_resonance_spectroscopy

... refers to nuclear magnetic resonance (NMR) spectroscopy of paramagnetic ... The magnetic field exerts its effect with both angular and a 1/r3 geometric dependences. Electron paramagnetic resonance - a ... This difference reflects the large magnetic moment of an electron (−1.00 μB), which is much greater than any nuclear magnetic ... They are large for many lanthanide complexes due to their strong magnetic anisotropy. NMR shift reagents such as EuFOD can ...

https://en.wikipedia.org/wiki/Paramagnetic_nuclear_magnetic_resonance_spectroscopy

... (fluorine NMR or 19F NMR) is an analytical technique used to detect and ... which is greater than that for proton nuclear magnetic resonance spectroscopy. 19F has a nuclear spin (I) of 1⁄2 and a high ... 19F magnetic resonance imaging (MRI) is a viable alternative to 1H MRI. The sensitivity issues can be overcome by using soft ... Articles with short description, Short description matches Wikidata, Nuclear magnetic resonance, Fluorine). ...

https://en.wikipedia.org/wiki/Fluorine-19_nuclear_magnetic_resonance_spectroscopy

... (2D NMR) is a set of nuclear magnetic resonance spectroscopy (NMR) ... ISBN 0-471-60178-0. (Use dmy dates from September 2015, Nuclear magnetic resonance spectroscopy). ... Types of 2D NMR include correlation spectroscopy (COSY), J-spectroscopy, exchange spectroscopy (EXSY), and nuclear Overhauser ... Application to nuclear magnetic resonance". Journal of Chemical Physics. 64 (5): 2229-46. Bibcode:1976JChPh..64.2229A. doi: ...

https://en.wikipedia.org/wiki/Two-dimensional_nuclear_magnetic_resonance_spectroscopy

Nuclear magnetic resonance Nuclear magnetic resonance spectroscopy of nucleic acids Nuclear magnetic resonance spectroscopy of ... Carbohydrate NMR spectroscopy is the application of nuclear magnetic resonance (NMR) spectroscopy to structural and ... ISBN 978-1-84973-577-3. Media related to Nuclear magnetic resonance spectroscopy of carbohydrates at Wikimedia Commons ( ... Nuclear Magnetic Resonance: NMR of carbohydrates. Royal Society of Chemistry. p. 383. ...

https://en.wikipedia.org/wiki/Nuclear_magnetic_resonance_spectroscopy_of_carbohydrates

Triple resonance experiments are a set of multi-dimensional nuclear magnetic resonance spectroscopy (NMR) experiments that link ... "Three-dimensional triple-resonance NMR spectroscopy of isotopically enriched proteins". Journal of Magnetic Resonance. 89 (3): ... These triple resonance experiments utilize the relatively large magnetic couplings between certain pairs of nuclei to establish ... The intra-residue resonances are usually stronger than the inter-residues one. This experiment correlates the resonances of the ...

https://en.wikipedia.org/wiki/Triple-resonance_nuclear_magnetic_resonance_spectroscopy

Two-dimensional nuclear magnetic resonance spectroscopy Triple-resonance nuclear magnetic resonance spectroscopy Witanowski, M ... Nitrogen-15 nuclear magnetic resonance spectroscopy (nitrogen-15 NMR spectroscopy, or just simply 15N NMR) is a version of ... "Nitrogen Magnetic Resonance Spectroscopy". Annual Reports on NMR Spectroscopy (2), pp 125-152. doi:10.1016/S0066-4103(08)60321- ... Nitrogen-15 is frequently used in nuclear magnetic resonance spectroscopy (NMR), because unlike the more abundant nitrogen-14, ...

https://en.wikipedia.org/wiki/Nitrogen-15_nuclear_magnetic_resonance_spectroscopy

NMR spectroscopy Nuclear magnetic resonance Nuclear magnetic resonance spectroscopy of carbohydrates Nuclear magnetic resonance ... Nuclear magnetic resonance spectroscopy of proteins (usually abbreviated protein NMR) is a field of structural biology in which ... Traditionally, nuclear magnetic resonance spectroscopy has been limited to relatively small proteins or protein domains. This ... Progress in Nuclear Magnetic Resonance Spectroscopy. 45 (3-4): 315-337. doi:10.1016/j.pnmrs.2004.08.003. Pervushin K, Riek R, ...

https://en.wikipedia.org/wiki/Nuclear_magnetic_resonance_spectroscopy_of_proteins

... most commonly known as NMR spectroscopy of stereoisomers is a chemical ... 2] Ultraviolet-visible spectroscopy of stereoisomers (Nuclear magnetic resonance spectroscopy). ... As with NMR spectroscopy in general, good resolution requires a high signal-to-noise ratio, clear separation between peaks for ... "NMR Through the Looking Glass: Uses of NMR Spectroscopy in the Analysis and Synthesis of Chiral Pharmaceuticals." 1994. [ ...

https://en.wikipedia.org/wiki/Nuclear_magnetic_resonance_spectroscopy_of_stereoisomers

Brain metabolism Magnetic resonance imaging Nuclear magnetic resonance spectroscopy Fourier transform spectroscopy Adjusting ... Functional magnetic resonance spectroscopy of the brain (fMRS) uses magnetic resonance imaging (MRI) to study brain metabolism ... "Functional diffusion-weighted magnetic resonance spectroscopy of the human primary visual cortex at 7 T". Magnetic Resonance in ... Magnetic resonance imaging, Neuroimaging, Spectroscopy, Nuclear magnetic resonance). ...

https://en.wikipedia.org/wiki/Functional_magnetic_resonance_spectroscopy_of_the_brain

Nucleic acid NMR is the use of nuclear magnetic resonance spectroscopy to obtain information about the structure and dynamics ... ISBN 0-19-508467-5. (Nuclear magnetic resonance spectroscopy, Nucleic acids, Biophysics). ... Applications for multidimensional nuclear magnetic resonance spectroscopy". Methods in Enzymology. 338: 261-283. doi:10.1016/ ... ISBN 0-19-508467-5. Kan, Lou-sing; Ts'o, Paul O. P. (1986). "Nuclear Magnetic Resonance Studies of Nucleic Acids". In Chien, ...

https://en.wikipedia.org/wiki/Nuclear_magnetic_resonance_spectroscopy_of_nucleic_acids

Nuclear magnetic resonance (NMR) Nuclear magnetic resonance spectroscopy of carbohydrates Nuclear magnetic resonance ... ISBN 0-7216-3184-3. Pregosin, P. S.; Rueegger, H. (2004). "Nuclear magnetic resonance spectroscopy". In McCleverty, Jon A.; ... spectroscopy of nucleic acids Nuclear magnetic resonance spectroscopy of proteins Proton NMR Relaxation (NMR) Residual dipolar ... ISBN 0-7167-8759-8. Carrington, Alan; McLachlan, Andrew D. (1967). Introduction to Magnetic Resonance. Harper & Row. p. 47. the ...

https://en.wikipedia.org/wiki/J-coupling

Nuclear Magnetic Resonance Spectroscopy. ISBN 978-0130334510. Paul S. Pregosin, Roland W. Kunz (2012). 31P and 13C NMR of ... An important technique for the characterization of metal-PR3 complexes is 31P NMR spectroscopy. Substantial shifts occur upon ...

https://en.wikipedia.org/wiki/Metal-phosphine_complex

... or near infrared spectroscopy (NIRS). Nuclear magnetic resonance (NMR) is what MRI and fMRI technologies were derived from, but ... magnetic resonance spectroscopy (for measuring some key metabolites such as N-acetylaspartate and lactate within the living ... transcranial magnetic stimulation, and nuclear magnetic resonance. To begin with, much of the recent progress has had to do not ... "Nuclear Magnetic Resonance Spectroscopy." Online at http://www.shu.ac.uk/schools/sci/chem/tutorials/molspec/nmr1.htm Shorey, ...

https://en.wikipedia.org/wiki/History_of_neuroimaging

Nelson, J. H. (2003). Nuclear magnetic resonance spectroscopy. Prentice Hall. pp. 129-139. ISBN 978-0-13-033451-0. Danielson, ... Fluorine compounds are highly amenable to nuclear magnetic resonance (NMR), because fluorine-19 has a nuclear spin of 1⁄2, a ... Magnetic Resonance in Medicine. 39 (1): 85-88. doi:10.1002/mrm.1910390114. PMID 9438441. S2CID 35741393. Gabriel, J. L.; Miller ... high nuclear magnetic moment, and a high magnetogyric ratio. Fluorine compounds typically have a fast NMR relaxation, which ...

https://en.wikipedia.org/wiki/Biological_aspects_of_fluorine

"Nuclear magnetic resonance spectroscopy". Sheffield Hallam University. Gladys H. Fuller (1975). "Nuclear spins and moments" ( ... Magnetic moment Nuclear magneton Gyromagnetic ratio Electron magnetic moment Nucleon magnetic moment Deuterium magnetic moment ... The nuclear magnetic moment is the magnetic moment of an atomic nucleus and arises from the spin of the protons and neutrons. ... The nuclear magnetic moment is not sum of nucleon magnetic moments, this property being assigned to the tensorial character of ...

https://en.wikipedia.org/wiki/Nuclear_magnetic_moment

Progress in Nuclear Magnetic Resonance Spectroscopy. 70: 25-49. doi:10.1016/j.pnmrs.2012.10.001. PMC 3613763. PMID 23540575. " ... Magnetic Resonance in Medicine. 71 (2): 561-569. doi:10.1002/mrm.24691. PMC 3718873. PMID 23447121. Yu, J.-X.; Hallac, R. R.; ... Magnetic Resonance in Medicine. 62 (2): 357-364. doi:10.1002/mrm.22020. PMC 4426862. PMID 19526495. Hallac, R. R.; Zhou, H.; ... Magnetic Resonance in Medicine. 71 (5): 1863-1873. doi:10.1002/mrm.24846. PMC 3883977. PMID 23813468. Zhang, Z.; Hallac, R. R ...

https://en.wikipedia.org/wiki/Hexafluorobenzene

Progress in Nuclear Magnetic Resonance Spectroscopy. 109: 1-50. doi:10.1016/j.pnmrs.2018.06.001. PMID 30527132. S2CID 54474265 ... and magnetic resonance imaging (MRI) are used to differentiate intrahepatic cholestasis from extrahepatic cholestasis. ...

https://en.wikipedia.org/wiki/Cholestasis

Progress in Nuclear Magnetic Resonance Spectroscopy. 80: 1-11. doi:10.1016/j.pnmrs.2014.03.001. PMC 4057650. PMID 24924264.{{ ... Journal of Magnetic Resonance. 160 (1): 65-73. Bibcode:2003JMagR.160...65S. doi:10.1016/S1090-7807(02)00014-9. PMID 12565051.{{ ... Nuclear magnetic resonance, National Institutes of Health people, National Institutes of Health faculty, Alumni of University ... Marius Clore Orcid ID Marius Clore on Landmark Article in the Journal of Magnetic Resonance Marius Clore Lecture on "Transient ...

https://en.wikipedia.org/wiki/G._Marius_Clore

Progress in Nuclear Magnetic Resonance Spectroscopy. 84-85: 14-32. doi:10.1016/j.pnmrs.2014.11.001. PMC 4325279. PMID 25669739 ... Bax, Ad (December 2011). "Triple resonance three-dimensional protein NMR: Before it became a black box". Journal of Magnetic ... Clore, Marius G. (2011). "Adventures in Biomolecular NMR". Encyclopedia of Magnetic Resonance (PDF). John Wiley & Sons. doi: ... Torchia, Dennis A. (2012). "Adventures in Biomolecular NMR". Encyclopedia of Magnetic Resonance. John Wiley & Sons. doi:10.1002 ...

https://en.wikipedia.org/wiki/Dennis_Torchia

"In vivo methods and applications of xenon-129 magnetic resonance". Progress in Nuclear Magnetic Resonance Spectroscopy. 122: 42 ... Progress in Nuclear Magnetic Resonance Spectroscopy. 31 (4): 293-315. doi:10.1016/s0079-6565(97)00007-1. Duckett, S. B.; Mewis ... "Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy". Nat. Med. 13 (11 ... "Enabling Clinical Technologies for Hyperpolarized 129 Xenon Magnetic Resonance Imaging and Spectroscopy". Angewandte Chemie ...

https://en.wikipedia.org/wiki/Hyperpolarization_(physics)

Progress in Nuclear Magnetic Resonance Spectroscopy. 64: 4-28. doi:10.1016/J.PNMRS.2011.10.002. ISSN 0079-6565. PMID 22578315. ... Electron Paramagnetic Resonance Spectroscopy (MPI-bpc, Uni-Che) - Georg-August-Universität Göttingen". www.uni-goettingen.de ( ... Her research considers the development of electron paramagnetic resonance spectroscopy for the characterisation of biomolecules ... "High-field pulsed electron-electron double resonance spectroscopy to determine the orientation of the tyrosyl radicals in ...

https://en.wikipedia.org/wiki/Marina_Bennati

Ammerlaan, C. A. J.; Kemp, R. V. (1985). "Magnetic resonance spectroscopy in semiconducting diamond". Journal of Physics C: ... The defects can be detected by different types of spectroscopy, including electron paramagnetic resonance (EPR), luminescence ... There is a tradition in diamond spectroscopy to label a defect-induced spectrum by a numbered acronym (e.g. GR1). This ... Baker, J.; Van Wyk, J.; Goss, J.; Briddon, P. (2008). "Electron paramagnetic resonance of sulfur at a split-vacancy site in ...

https://en.wikipedia.org/wiki/Crystallographic_defects_in_diamond

"Magnetic resonance spectroscopy and imaging for the study of fossils". Magnetic Resonance Imaging. Elsevier BV. 34 (6): 730-742 ... List of neuroimaging software Magnetic immunoassay Magnetic particle imaging Magnetic resonance elastography Magnetic Resonance ... "Magnetic Resonance, a critical peer-reviewed introduction". European Magnetic Resonance Forum. Retrieved 17 November 2014. ... Magnetic resonance spectroscopy (MRS) is used to measure the levels of different metabolites in body tissues, which can be ...

https://en.wikipedia.org/wiki/Magnetic_resonance_imaging

Progress in Nuclear Magnetic Resonance Spectroscopy. 94-95: 1-10. doi:10.1016/j.pnmrs.2016.01.004. PMID 27247282. Nobel Prizes ... The atomic structure models obtained by X-ray crystallography and biomolecular NMR spectroscopy can be docked into the much ... Sinha C, Arora K, Moon CS, Yarlagadda S, Woodrooffe K, Naren AP (October 2014). "Förster resonance energy transfer - an ... The biomacromolecular complexes are studied structurally by X-ray crystallography, NMR spectroscopy of proteins, cryo-electron ...

https://en.wikipedia.org/wiki/Macromolecular_assembly

Progress in Nuclear Magnetic Resonance Spectroscopy. 28 (1): 37-52. doi:10.1016/0079-6565(95)01019-X. Lécuyer, p. 101-103 ... They also were interested in nuclear magnetic resonance technology. One of Varian Associates' major contracts in the 1950s was ...

https://en.wikipedia.org/wiki/Varian_Associates

Progress in Nuclear Magnetic Resonance Spectroscopy. 74: 1-32. doi:10.1016/j.pnmrs.2013.04.002. PMID 24083460. (All articles ... Tofts, PS; Buckley, DL (1997). "Modeling tracer kinetics in dynamic Gd-DTPA MR imaging". Journal of Magnetic Resonance Imaging ... Magnetic Resonance Imaging. 5 (3): 201-08. doi:10.1016/0730-725X(87)90021-X. PMID 3626789. Cheng, K; Koeck, PJ; Elmlund, H; ... "Magnetic resonance diffusion-perfusion mismatch in acute ischemic stroke: An update". World Journal of Radiology. 4 (3): 63-74 ...

https://en.wikipedia.org/wiki/Perfusion_MRI

Progress in Nuclear Magnetic Resonance Spectroscopy. 22 (5): 453-485. doi:10.1016/0079-6565(90)80007-5. (Nuclear magnetic ... Vanadium-51 nuclear magnetic resonance (51V NMR spectroscopy) is a method for the characterization of vanadium-containing ... Its resonance frequency is close to that of 13C (gyromagnetic ratio = 6.728284 rad T−1s−1). The chemical shift dispersion is ... The nucleus is quadrupolar with I = 7/2, which is not favorable for NMR spectroscopy. The quadrupole moment is small, thus the ...

https://en.wikipedia.org/wiki/Vanadium-51_nuclear_magnetic_resonance

Progress in Nuclear Magnetic Resonance Spectroscopy. 17: 33-67. doi:10.1016/0079-6565(85)80005-4. Kuhn, Lars T.; et al., eds. ( ... Goldman, Maurice (1970). Spin Temperature and Nuclear Magnetic Resonance in Solids. Oxford University Press. ISBN 978-0-19- ... 2008). "High-Field Dynamic Nuclear Polarization for Solid and Solution Biological NMR". Applied Magnetic Resonance. 34 (3-4): ... Applied Magnetic Resonance. 5 (2): 161-176. doi:10.1007/BF03162519. ISSN 0937-9347. Ni, Qing Zhe; Daviso E; Can TV; Markhasin E ...

https://en.wikipedia.org/wiki/Dynamic_nuclear_polarization

His work focuses on the theory of magnetic spectroscopies (electron paramagnetic resonance, magnetic circular dichroism) and ... Neese, Frank (2009). "Prediction of molecular properties and molecular spectroscopy with density functional theory: From ... "Molecular Theory and Spectroscopy". www.kofo.mpg.de. Retrieved 16 December 2021. Neese, Frank (2012). "The ORCA program system ... where he heads the department of Molecular Theory and Spectroscopy. In 2018 he moved to Mülheim's other Max Planck Institute, ...

https://en.wikipedia.org/wiki/Frank_Neese

... while for a silicon particle there are pronounced magnetic dipole and quadrupole resonances. For metal particles, the peak ... Wriedt, Thomas (2008). "Mie theory 1908, on the mobile phone 2008". Journal of Quantitative Spectroscopy & Radiative Transfer. ... is designed around the overlap of resonances of Mie electric and magnetic dipole scattering coefficients. The particle usually ... maximum forward scattering is observed at wavelengths longer than the wavelength of magnetic dipole resonance, and maximum ...

https://en.wikipedia.org/wiki/Mie_scattering

... has also been crystallized and has been studied by nuclear magnetic resonance spectroscopy in the presence of RNA. The N ...

https://en.wikipedia.org/wiki/Coronavirus_nucleocapsid_protein

... magnetic resonance spectroscopy and magnet engineering. The proposal was accepted, the National Magnet Laboratory was ... high magnetic field nuclear magnetic resonance (NMR); pioneering work on biomagnetism; a range of applications of magnet ... plasma interactions in high magnetic fields and laser plasma diagnostics. He was also interested in the use of high magnetic ... He received in 1949 from MIT his Ph.D. under Sanborn C. Brown with thesis The effect of magnetic field on the breakdown of ...

https://en.wikipedia.org/wiki/Benjamin_Lax

... with other local scientists for him and his students to have access to Magic-angle-Spinning Nuclear Magnetic Resonance, Atomic ... polarized infrared spectroscopy and Raman spectroscopy, bulk- and milli-Mössbauer spectroscopy, electron microprobe and a micro ... infrared spectroscopy and Mössbauer spectroscopy, and for making the acquaintance of prominent scientists. In particular, he ... and one can combine Rietveld structure refinement and IR spectroscopy to derive patterns of SRO. Thus H can act as a local ...

https://en.wikipedia.org/wiki/Frank_Hawthorne

... a magnetic resonance technique analogous to nuclear magnetic resonance (NMR) or electron spin resonance (ESR) spectroscopy. ... which is also called level crossing resonance (LCR). The latter employs a magnetic field applied longitudinally to the ... Muonium is usually studied by muon spin rotation, in which the Mu atom's spin precesses in a magnetic field applied transverse ... p. 4. ISBN 978-0-521-24241-7. J.H. Brewer (1994). "Muon Spin Rotation/Relaxation/Resonance". Encyclopedia of Applied Physics. ...

https://en.wikipedia.org/wiki/Muonium

These resonances are the basis for a number of experimental techniques for detecting defects. The conductance method measures ... The dual of the capacitor is the inductor, which stores energy in a magnetic field rather than an electric field. Its current- ... 6.6 "Modulation Spectroscopy". ISBN 3-540-25470-6. Kaplan, Daniel M.; White, Christopher G. (2003). Hands-On Electronics: A ... Sophisticated modulation spectroscopy measurement methods based upon modulating the crystal structure by pressure or by other ...

https://en.wikipedia.org/wiki/Capacitor

To do this, he has extensively used techniques such as Nuclear Magnetic Resonance spectroscopy, Infrared spectroscopy, and ...

https://en.wikipedia.org/wiki/Padmanabhan_Balaram

"Correlates of alpha rhythm in functional magnetic resonance imaging and near infrared spectroscopy". NeuroImage. 20 (1): 145-58 ... "Near-infrared spectroscopy: does it function in functional activation studies of the adult brain?". International Journal of ...

https://en.wikipedia.org/wiki/Petra_Ritter_(neuroscientist)

... circular dichroism spectroscopy, nuclear magnetic resonance spectroscopy, UV-visible spectroscopy and related experiments. ... theophylline and adenine nucleobases using l-cysteine functionalized magnetic nanoparticles (LCMNP) as magnetic reusable ... In magnetic chemistry, nanoparticles can be used for catalyst support for medicinal use. Besides conventional catalysis, ... Some techniques that can be used to characterize functionalized nanomaterial catalysts include X-ray photoelectron spectroscopy ...

https://en.wikipedia.org/wiki/Nanomaterial-based_catalyst

For instance, nuclear magnetic resonance frequencies depend on the molecular environment. Furthermore, nuclear spin-lattice ... NMR spectroscopy "Electrical Fast Field Cycling Relaxometry". spinscope.com. Retrieved 22 April 2012. (Articles with short ... magnetic fields and can be done using static magnetic fields. Electrical field cycling requires switchable fields that are ... Field Cycling (FC) is a measurement method which uses variable magnetic fields to measure the magnetization of a sample. Fast ...

https://en.wikipedia.org/wiki/Field_cycling

... spectroscopic and magnetic properties (i.e. magnetic field induced ring current) A number of exceptions to these conventional ... Studies of these complexes by 1H NMR spectroscopy showed a large difference in chemical shift values for methylene protons of ... the resonance stabilization of homoaromaticity is offset by the strain in forming the homoconjugate bridge. In fact, the ... The magnetic field of the NMR could thus induce a ring current in the ion, responsible for the significant differences in ...

https://en.wikipedia.org/wiki/Homoaromaticity

"Energy contribution of octanoate to intact rat brain metabolism measured by 13C nuclear magnetic resonance spectroscopy". J ... of blood lactate to brain energy metabolism in humans measured by dynamic 13C nuclear magnetic resonance spectroscopy". J ... of cerebral oxygenation changes during brain activation by near-infrared spectroscopy and functional magnetic resonance imaging ... "Borders of multiple visual areas in human revealed by functional magnetic resonance imaging" (PDF). Science. 268 (5212): 889- ...

https://en.wikipedia.org/wiki/Brain

Cold vapour atomic fluorescence spectroscopy Coleman-Mandula theorem Coleman-Weinberg potential Cole-Cole equation Colin ... Copenhagen interpretation Copernican principle Copper indium gallium selenide solar cells Core-excited shape resonance Core/ ... Composite fermion Composite field Composite gravity Composite particle Compressed fluid Compressed magnetic flux generator ... Cyclic model Cyclone Cyclonic separation Cyclops laser Cyclotron Cyclotron radiation Cyclotron resonance Cylinder stresses ...

https://en.wikipedia.org/wiki/Index_of_physics_articles_(C)

... protein nuclear magnetic resonance spectroscopy - protein P16 - protein P34cdc2 - protein precursor - protein structure ... nuclear magnetic resonance - NMR - nuclear protein - nucleic acid - nucleic acid regulatory sequence - nucleic acid repetitive ... UV/VIS spectroscopy vaccine - vacuole - valence - valine - van der Waals force - van der Waals radius - vapor pressure - vapour ... atomic absorption spectroscopy - atomic mass - atomic mass unit - atomic nucleus - atomic number - atomic orbital - atomic ...

https://en.wikipedia.org/wiki/Index_of_biochemistry_articles

This is an alternative method to the use of nuclear quadrupole resonance spectroscopy. The selection rule for rotational ... Magnetic-dipole-allowed transitions can occur in paramagnetic molecules such as dioxygen, O 2 and nitric oxide, NO In Raman ... Rotational spectroscopy is sometimes referred to as pure rotational spectroscopy to distinguish it from rotational-vibrational ... The theoretical framework underpinning FTMW spectroscopy is analogous to that used to describe FT-NMR spectroscopy. The ...

https://en.wikipedia.org/wiki/Rotational_spectroscopy

... has been elucidated using nuclear magnetic resonance (NMR) spectroscopy. tRNA-intron endonucleases identify introns along pre- ...

https://en.wikipedia.org/wiki/TRNA-intron_endonuclease

... infrared spectroscopies, Raman amplification, optical spectroscopies, voltammetry, nuclear magnetic resonance, and computer ... Atomic Spectroscopy. 59 (10-11): 1619-1625. Bibcode:2004AcSpe..59.1619S. doi:10.1016/j.sab.2004.07.027. Haude, Mary Elizabeth ( ... microscopic analysis of the mural paintings and fourier transform infrared spectroscopy. After the formula for the production ...

https://en.wikipedia.org/wiki/Maya_blue

This has important applications in magnetic resonance imaging. The potential energy of an electron in an atom is negative ... Electron emission techniques such as X-ray photoelectron spectroscopy (XPS) and Auger electron spectroscopy (AES), which ... The magnetic field produced by an atom-its magnetic moment-is determined by these various forms of angular momentum, just as a ... This is caused by the interaction of the magnetic field with the magnetic moment of the atom and its electrons. Some atoms can ...

https://en.wikipedia.org/wiki/Atom

J-coupling between pairs of nuclear spins is an important feature of nuclear magnetic resonance (NMR) spectroscopy as it can ... This is an approximation which is good as long as any external magnetic fields are weak. In larger magnetic fields, these two ... In atomic physics, spin-orbit coupling, also known as spin-pairing, describes a weak magnetic interaction, or coupling, of the ... Angular momentum coupling in atoms is of importance in atomic spectroscopy. Angular momentum coupling of electron spins is of ...

https://en.wikipedia.org/wiki/Angular_momentum_coupling

He received training in practical nuclear magnetic resonance spectroscopy from Venkataraman Thanabal. From 1993 to 1996, Clubb ... He is the lab director of the Clubb Lab and co-director and staff researcher at the Nuclear Magnetic Resonance (NMR) Core ...

https://en.wikipedia.org/wiki/Robert_T._Clubb

Quantum electronics, Spectroscopy). ... Electrically detected magnetic resonance (EDMR) is a materials ... "Electrically detected magnetic resonance in ion-implanted Si:P nanostructures". Applied Physics Letters. 89 (18): 182115. arXiv ... "Theory of time-domain measurement of spin-dependent recombination with pulsed electrically detected magnetic resonance". ... To perform a pulsed EDMR experiment, the system is first initialised by placing it in a magnetic field. This orients the spins ...

https://en.wikipedia.org/wiki/Electrically_detected_magnetic_resonance

... the use of infra-red gas lasers combined with high magnetic fields to carry out cyclotron resonance and impurity spectroscopy ... His early work was on the cyclotron resonance of semiconductors moving to magnetophonon resonance. He and his team of students ...

https://en.wikipedia.org/wiki/R._A._Stradling

The institute has in-house facilities for bioinformatics, flow cytometry, microscopy, genomics, nuclear magnetic resonance (NMR ... Molecular Imaging; research includes X-ray crystallography, NMR, spectroscopy, and microscopy. ...

https://en.wikipedia.org/wiki/La_Trobe_Institute_for_Molecular_Science

... and the reconstruction of conformations of molecules via nuclear magnetic resonance spectroscopy. Bruce Hendrickson defined a ...

https://en.wikipedia.org/wiki/Rigidity_matroid

... mathematics at the Estonian Academy of Sciences and was highly regarded in his work into solid-state nuclear magnetic resonance ... now highlighy regarded demonstrated in 1980 that high-resolution NMR spectroscopy could be applied profitably to inorganic ...

https://en.wikipedia.org/wiki/Endel_Lippmaa

... of naturally occurring hydrogen and is used in industrial processes like nuclear reactors and Nuclear Magnetic Resonance. ... Atomic spectroscopy shows that there is a discrete infinite set of states in which a hydrogen (or any) atom can exist, contrary ... The spin of the electron has an associated magnetic moment which interacts with this magnetic field. This effect is also ... They are unbound resonances located beyond the neutron drip line; this results in prompt emission of a neutron. The formulas ...

https://en.wikipedia.org/wiki/Hydrogen_atom

... and magnetic resonance spectroscopy and imaging. His books on System Identification, Spectral Analysis, and Space-Time Coding ...

https://en.wikipedia.org/wiki/Peter_Stoica

The magnetic properties are closely interrelated to the electronic properties in SWNHs. In one electronic spin resonance (ESR) ... The detailed structure of SWNHs was further extensively analyzed with X-ray photoelectron spectroscopy (XPS) and Raman ... Electronic interactions within the nanoensemble were probed by optical spectroscopy, indicating electron transfer between the ... spectroscopy. The considerably strong peak due to single bonding carbons was observed in C1s XPS spectrum of SWNH. This peak ...

https://en.wikipedia.org/wiki/Single-walled_carbon_nanohorn

Biophysical Nuclear Magnetic Resonance Spectroscopy Section. of the Laboratory of Chemical Physics ...

https://www.niddk.nih.gov/research-funding/at-niddk/labs-branches/laboratory-chemical-physics/biophysical-nuclear-magnetic-resonance-spectroscopy-section

Magnetic Resonance Spectroscopy website. Here you will find a wealth of relevant information about the Magnetic Resonance ... Ever since the discovery of Magnetic Resonance Imaging (MRI), the field of MR has diverged into MRI and Magnetic Resonance ... Spectroscopy (MRS). Whereas MRI typically observes a water signal, MRS detects all chemicals above a minimum concentration ... Spectroscopy Group and the current ongoing research from its impressive roster of faculty. ...

https://medicine.yale.edu/bioimaging/mrs/

Osprey: Open-Source Processing, Reconstruction & Estimation of Magnetic Resonance Spectroscopy Data. View ORCID ProfileGeorg ... Osprey: Open-Source Processing, Reconstruction & Estimation of Magnetic Resonance Spectroscopy Data Message Subject (Your Name ... Background Processing and quantitative analysis of magnetic resonance spectroscopy (MRS) data are far from standardized and ...

https://www.biorxiv.org/content/10.1101/2020.02.12.944207v2

Nuclear magnetic resonance spectroscopy is a powerful and versatile spectroscopic technique and novel applications are ... As nmr spectroscopy is a precisely mathematical subject, the theoretical applications later employed are briefly outlined. The ... This thesis concerns the application of nmr spectroscopy to the study and definition of both the time dependent and the time ... Upon this basis and upon results published for studies of aziridine inversion barriers, an estimate of the resonance energy in ...

https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.795761

Hyperpolarized [1-13C]pyruvate magnetic resonance spectroscopic imaging (MRSI) is a non-invasive metabolic imaging modality ... Browsing by Subject "13C magnetic resonance spectroscopy". 0-9. A. B. C. D. E. F. G. H. I. J. K. L. M. N. O. P. Q. R. S. T. U. ...

https://scholarship.rice.edu/browse?type=subject&value=13C+magnetic+resonance+spectroscopy

... detected by proton spectroscopy performed within 18 hours of suspected birth asphyxia, is associated with adverse outcome, and ... Thirty-one term infants suspected of having had birth asphyxia and seven control infants underwent proton magnetic resonance ... The aim of the study was to test the hypotheses that elevated cerebral lactate, detected by proton spectroscopy performed ... spectroscopy, using three-dimensional chemical shift imaging, within 18 hours of birth. Adverse outcome was defined as death or ...

https://pubmed.ncbi.nlm.nih.gov/10075092/?dopt=Abstract

Whole Brain 3-D Magnetic Resonance Spectroscopy: Advancing the Exploration of Neuropsychiatric Disorders. By Amit Anand, and ... Whole Brain 3-D Magnetic Resonance Spectroscopy. MRSI, also known as chemical shift imaging, records spectroscopic data for a ... Although techniques such as proton magnetic resonance spectroscopy (MRS) have yielded insight into the workings of the brain, ... In addition to single-voxel spectroscopy, multivoxel MR spectroscopic imaging (MRSI) has long been used in spectroscopy studies ...

https://robbreport.com/shelter/art-collectibles/whole-brain-3-d-magnetic-resonance-spectroscopy-advancing-exploration-neuropsychiatric-238202/

Supersaturation in the Presence of Polysorbates as Solubilizing Additives by Solution Nuclear Magnetic Resonance Spectroscopy. ...

https://www.merck.com/publication/mechanistic-investigation-of-drug-supersaturation-in-the-presence-of-polysorbates-as-solubilizing-additives-by-solution-nuclear-magnetic-resonance-spectroscopy/

This article discusses the advantages and disadvantages of using solid-state NMR spectroscopy for the analysis of ... Solid-state nuclear magnetic resonance (SSNMR) spectroscopy is an excellent technique for performing many different types of ... Solid-state nuclear magnetic resonance (SSNMR) spectroscopy has several advantages over these techniques. First, it is ... 2. P.A. Tishmack, D.E. Bugay, and S.R. Byrn, Solid-State Nuclear Magnetic Resonance Spectroscopy-Pharmaceutical Applications, ...

https://www.pharmtech.com/view/solid-state-nuclear-magnetic-resonance-spectroscopy-analyzing-polymorphic-drug-forms-and-formulation

Muscle abnormalities in juvenile dermatomyositis patients : P-31 magnetic resonance spectroscopy studies. In: Arthritis and ... Muscle abnormalities in juvenile dermatomyositis patients: P-31 magnetic resonance spectroscopy studies. Arthritis and ... Muscle abnormalities in juvenile dermatomyositis patients : P-31 magnetic resonance spectroscopy studies. / Park, JANE H.; ... title = "Muscle abnormalities in juvenile dermatomyositis patients: P-31 magnetic resonance spectroscopy studies", ...

https://pennstate.pure.elsevier.com/en/publications/muscle-abnormalities-in-juvenile-dermatomyositis-patients-p-31-ma

Neuronavigation using three-dimensional proton magnetic resonance spectroscopy data. Berkay Kanberoglu, Nina Z. Moore, David ... Neuronavigation using three-dimensional proton magnetic resonance spectroscopy data. Stereotactic and Functional Neurosurgery. ... Neuronavigation using three-dimensional proton magnetic resonance spectroscopy data. / Kanberoglu, Berkay; Moore, Nina Z.; ... Neuronavigation using three-dimensional proton magnetic resonance spectroscopy data. In: Stereotactic and Functional ...

https://asu.pure.elsevier.com/en/publications/neuronavigation-using-three-dimensional-proton-magnetic-resonance

Functional Magnetic Resonance Spectroscopy: The "New" MRS in Psychiatry Research. Proton magnetic resonance spectroscopy (¹H ... Functional Magnetic Resonance Spectroscopy: The "New" MRS in Psychiatry Research Kolloquium: Functional Magnetic Resonance ...

https://www.mpib-berlin.mpg.de/events/22318/63631

the Experts Working Group on Magnetic resonance spectroscopy in the rodent brain. Magnetic resonance spectroscopy in the ... the Experts Working Group on Magnetic resonance spectroscopy in the rodent brain. / Magnetic resonance spectroscopy in the ... the Experts Working Group on Magnetic resonance spectroscopy in the rodent brain 2021, Magnetic resonance spectroscopy in the ... the Experts Working Group on Magnetic resonance spectroscopy in the rodent brain (2021). Magnetic resonance spectroscopy in ...

https://mayoclinic.pure.elsevier.com/en/publications/magnetic-resonance-spectroscopy-in-the-rodent-brain-experts-conse

Guanosine 5 diphosphate, 3 diphosphate : Assignment of structure by 13C nuclear magnetic resonance spectroscopy. / Que, L.; ... Guanosine 5 diphosphate, 3 diphosphate: Assignment of structure by 13C nuclear magnetic resonance spectroscopy. Proceedings ... Guanosine 5 diphosphate, 3 diphosphate : Assignment of structure by 13C nuclear magnetic resonance spectroscopy. In: ... Guanosine 5 diphosphate, 3 diphosphate: Assignment of structure by 13C nuclear magnetic resonance spectroscopy. ...

https://experts.umn.edu/en/publications/guanosine-5-diphosphate-3-diphosphate-assignment-of-structure-by-

Magnetic resonance spectroscopy (MRS) was used to quantify concentrations of NAA, glutamate and other brain metabolites in ... Magnetic resonance spectroscopy (MRS) was used to quantify concentrations of NAA, glutamate and other brain metabolites in ... In Vivo Measurement of Brain GABA Concentrations by Magnetic Resonance Spectroscopy in Smelters Occupationally Exposed to ... In Vivo Measurement of Brain GABA Concentrations by Magnetic Resonance Spectroscopy in Smelters Occupationally Exposed to ...

https://www.zora.uzh.ch/id/eprint/41403/

Rotational correlation times of proteins by deuterium nuclear magnetic resonance spectroscopy ... Nuclear magnetic resonance studies of amino acids and proteins. ... Magnetic resonance spectroscopy of wheat proteins: a magic- ... Rotational correlation times of proteins by deuterium nuclear magnetic resonance spectroscopy. Nuclear magnetic resonance ... Nuclear magnetic resonance studies of amino acids and proteins. Deuterium nuclear magnetic resonance relaxation of ...

https://eurekamag.com/research/018/032/018032479.php

Localized Proton Magnetic Resonance Spectroscopy at 7 Tesla in the Rat Brain: Metabolite Concentration Estimates Using QUEST ... Localized Proton Magnetic Resonance Spectroscopy at 7 Tesla in the Rat Brain: Metabolite Concentration Estimates Using QUEST ... Localized Proton Magnetic Resonance Spectroscopy at 7 Tesla in the Rat Brain: Metabolite Concentration Estimates Using QUEST ...

https://www.creatis.insa-lyon.fr/site7/en/publications/CUDA-06d

Using magnetic resonance spectroscopy, researchers at the University of New South Wales Brain Sciences (Sydney, Australia) ... Using magnetic resonance spectroscopy, researchers at the University of New South Wales Brain Sciences (Sydney, Australia) ... Sleep specialists from the Woolcock Institute at Sydney University used magnetic resonance spectroscopy to study a dozen male ... All PublicationsSpectroscopySpectroscopy SupplementsApplication NotebookE-Books. Columns. All ColumnsAtomic Perspectives ...

https://www.spectroscopyonline.com/view/magnetic-resonance-spectroscopy-and-sleep-apnea

... as assessed by proton magnetic resonance spectroscopy, of the auditory cortex. ... rapid stimulation are associated with the cortical neurochemistry as determined by proton magnetic resonance spectroscopy. Our ... A combination of magnetoencephalography and proton magnetic resonance spectroscopy was used to correlate the electrophysiology ... From: The neurochemical basis of human cortical auditory processing: combining proton magnetic resonance spectroscopy and ...

https://bmcbiol.biomedcentral.com/articles/10.1186/1741-7007-4-25/figures/7

Nuclear Magnetic Resonance Spectroscopy. Structure and Dynamic Character of Allylic Grignard Reagents Citation:. G. M. ... "Nuclear Magnetic Resonance Spectroscopy. Structure and Dynamic Character of Allylic Grignard Reagents." Disc. Farad. Soc., 34, ...

https://gmwgroup.harvard.edu/publications/nuclear-magnetic-resonance-spectroscopy-structure-and-dynamic-character

The present study used magnetic resonance spectroscopy (MRS) to measure glutamate and its major metabolite glutamine in ... Effect of interferon-α on cortical glutamate in patients with hepatitis C: a proton magnetic resonance spectroscopy study ... Effect of interferon-α on cortical glutamate in patients with hepatitis C: a proton magnetic resonance spectroscopy study ... The present study used magnetic resonance spectroscopy (MRS) to measure glutamate and its major metabolite glutamine in ...

https://www.jenner.ac.uk/publications/401051

METHODS: We obtained localised proton magnetic resonance spectra bilaterally from the temporo-parietal cortex and cerebellum of ... Metabolic abnormalities in developmental dyslexia detected by 1H magnetic resonance spectroscopy. Rae C., Lee MA., Dixon RM., ... Magnetic Resonance Spectroscopy, Male, Parietal Lobe, Temporal Lobe ... METHODS: We obtained localised proton magnetic resonance spectra bilaterally from the temporo-parietal cortex and cerebellum of ...

https://www.dpag.ox.ac.uk/publications/525998

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https://www.wrh.ox.ac.uk/publications/473853

... control subjects without a history of cardiovascular disease underwent cardiac magnetic resonance imaging and spectroscopy for ... Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy, Male, Middle Aged, Myocardium, Prevalence ... Comprehensive cardiac magnetic resonance imaging and spectroscopy reveal a high burden of myocardial disease in HIV patients. ... Comprehensive cardiac magnetic resonance imaging and spectroscopy reveal a high burden of myocardial disease in HIV patients. ...

https://www.neuroscience.ox.ac.uk/publications/410935?c51df818-70f7-11ed-a561-061ab7f93640

... total correlation spectroscopy, and nuclear Overhauser enhancement spectroscopy) and a standard assignment procedure. Analysis ... The proton resonances of the NMR spectra of P196-267 were assigned using homonuclear two-dimensional techniques (double-quantum ... Structural characterization by nuclear magnetic resonance spectroscopy of a genetically engineered high-affinity calmodulin- ... Structural characterization by nuclear magnetic resonance spectroscopy of a genetically engineered high-affinity calmodulin- ...

https://hal-pasteur.archives-ouvertes.fr/pasteur-00167088

Plug-and-play Advanced Magnetic Resonance Spectroscopy. Dinesh K Deelchand1, Pierre-Gilles Henry1, James M Joers1, Edward ... spectroscopy step field success recently metabolite boxes scanner shim needs hospital short blue manually facilitate ...

https://archive.ismrm.org/2022/0490.html

Magnetic Resonance Spectroscopy. JK Science Journal of Medical Education and Research. 2006 July-Sept;8(3): 176-178. ...

https://imsear.searo.who.int/handle/123456789/171331

Hyperpolarized 29Si Magnetic Resonance Spectroscopy of Selectively Radical-Embedded Silica Nanoparticles. Quy Son Luu. Quynh ...

https://rdw.rowan.edu/csm_facpub/267/

Quantum control schemes for pulse sequence programming in magnetic resonance spectroscopy and related work on spectral analysis ... Quantum control schemes for pulse sequence programming in magnetic resonance spectroscopy and related work on spectral analysis ...

https://qyber.black/mrs

ACCESSIBILITY OF TRYPTOPHAN RESIDUES IN LYSOZYME USING PHOTOCHEMICALLY INDUCED DYNAMIC NUCLEAR-POLARIZATION SPECTROSCOPY. In: ... title = "PROTON NUCLEAR MAGNETIC-RESONANCE ASSIGNMENTS AND SURFACE ACCESSIBILITY OF TRYPTOPHAN RESIDUES IN LYSOZYME USING ... T1 - PROTON NUCLEAR MAGNETIC-RESONANCE ASSIGNMENTS AND SURFACE ACCESSIBILITY OF TRYPTOPHAN RESIDUES IN LYSOZYME USING ... PROTON NUCLEAR MAGNETIC-RESONANCE ASSIGNMENTS AND SURFACE ACCESSIBILITY OF TRYPTOPHAN RESIDUES IN LYSOZYME USING ...

https://research.rug.nl/nl/publications/proton-nuclear-magnetic-resonance-assignments-and-surface-accessi

Magnetic resonance imaging (MRI) and positron emission tomography (PET) can reveal brain anomalies associated with the condition. (medscape.com)
Functional magnetic resonance imaging, single-photon emission computed tomography, positron emission tomography, magnetic resonance spectroscopy, cortical excitability, and brain-derived neurotrophic factor consistently showed positive results. (drstubbeman.com)

One-Dimensional Fourier Transform Spectroscopy A major improvement in the signal-to-noise ra-tio of NMR spectra was achieved in 1964 by the conception of Fourier transform (FT) spectroscopy. (cliftonautotinting.com)
NUCLEAR MAGNETIC RESONANCE FOURIER TRANSFORM SPECTROSCOPY Nobel Lecture, December 9, 1992 by RICHARD R. ERNST Laboratorium für Physikalische Chemie, Eidgenössische Technische Hoch-schule, ETH-Zentrum 8092 Zurich, Switzerland The world of the nuclear spins is a true paradise for theoretical and experimental physicists. (cliftonautotinting.com)

Nuclear magnetic resonance spectroscopy is a powerful and versatile spectroscopic technique and novel applications are continually being devised for it. (bl.uk)
Hyperpolarized [1-13C]pyruvate magnetic resonance spectroscopic imaging (MRSI) is a non-invasive metabolic imaging modality intended to inform the state of metabolic reprograming and carbon flux in tumors. (rice.edu)
In addition to single-voxel spectroscopy, multivoxel MR spectroscopic imaging (MRSI) has long been used in spectroscopy studies, but MRSI studies often scan over a single slice and require long scan times to obtain useful information. (robbreport.com)
Objectives: We sought to develop a clinical workflow and uniquely capable custom software tool to integrate advanced 3-tesla 3D proton magnetic resonance spectroscopic imaging ( 1 H-MRSI) into industry standard image-guided neuronavigation systems, especially for use in brain tumor surgery. (elsevier.com)
Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. (musc.edu)

abstract = "Magnetic resonance imaging of a girl with giant axonal neuropathy revealed a progressive white matter disease. (vumc.nl)

Solid-state nuclear magnetic resonance (SSNMR) spectroscopy has several advantages over these techniques. (pharmtech.com)
Perspectives in High-resolution solid-state nuclear magnetic resonance, with emphasis on combined rotation and multiple-pulse spectroscopy. (uni-bayreuth.de)

Thirty-one term infants suspected of having had birth asphyxia and seven control infants underwent proton magnetic resonance spectroscopy, using three-dimensional chemical shift imaging, within 18 hours of birth. (nih.gov)
METHODS AND RESULTS: Volunteers with HIV who were undergoing combination antiretroviral therapy and age-matched control subjects without a history of cardiovascular disease underwent cardiac magnetic resonance imaging and spectroscopy for the determination of cardiac function, myocardial fibrosis, and myocardial lipid content. (ox.ac.uk)
Two hours after the final dose of ebselen/placebo, participants underwent proton magnetic resonance spectroscopy ((1)H MRS) at 7 tesla (T) with voxels placed in the anterior cingulate and occipital cortex. (ox.ac.uk)

METHODS: We obtained localised proton magnetic resonance spectra bilaterally from the temporo-parietal cortex and cerebellum of 14 well-defined dyslexic men and 15 control men of similar age. (ox.ac.uk)
The proton resonances of the NMR spectra of P196-267 were assigned using homonuclear two-dimensional techniques (double-quantum-filtered J-correlated spectroscopy, total correlation spectroscopy, and nuclear Overhauser enhancement spectroscopy) and a standard assignment procedure. (archives-ouvertes.fr)
The use of difference spectroscopy to improve the quality of the spectra of the desired components is illustrated for a variety of chemical systems. (cliftonautotinting.com)
In the single dI/dV-spectra Fano resonances can be observed. (uni-goettingen.de)

Complex mixtures, commonly encountered in metabolomics and food analytics, are now routinely measured by nuclear magnetic resonance (NMR) spectroscopy. (soton.ac.uk)

Comprehensive cardiac magnetic resonance imaging and spectroscopy reveal a high burden of myocardial disease in HIV patients. (ox.ac.uk)
Time-dependent cardiac structural and functional changes after kidney transplantation: a multi-parametric cardiac magnetic resonance study. (musc.edu)
Wang R, Zhou Z, Schoepf UJ, Varga-Szemes A, Strigenz A, Wang H, Liu Y, Xu L. Monitoring of anthracycline-induced myocardial injury using serial cardiac magnetic resonance: An animal study. (musc.edu)
The study is using a technique called magnetic resonance spectroscopy (MRS) during a cardiac magnetic resonance imaging (MRI) scan to determine whether energy metabolism is disrupted in heart failure and whether this contributes to poor heart function. (nih.gov)

Structural characterization by nuclear magnetic resonance spectroscopy of a genetically engineered high-affinity calmodulin-binding peptide derived from Bordetella pertussis adenylate cyclase. (archives-ouvertes.fr)
The characterization is critical as well, which including infrared spectroscopy, ultra-violet, nuclear magnetic resonance, differential scanning calorimetry, gel permeation chromatography and wide-angle X-ray diffraction. (cuny.edu)

Quantum control schemes for pulse sequence programming in magnetic resonance spectroscopy and related work on spectral analysis and quantification methods. (qyber.black)
USD 90.00 In addition, easier sampling combined with better sample‐to‐sample reproducibility and user‐to‐user spectral variation became available with attenuated total reflectance (ATR) probes and their application for in situ IR spectroscopy. (cliftonautotinting.com)
A common challenge in complex mixture 1H NMR spectroscopy is spectral crowding, which limits the assignment of molecular components to those molecules in relatively high abundance. (soton.ac.uk)
This effect leads to a screening of the impurity spin by the conduction band electrons and to a many-body resonance in the single particle spectral density of the localized d-orbital near the Fermi-Energy. (uni-goettingen.de)

The aim of the study was to test the hypotheses that elevated cerebral lactate, detected by proton spectroscopy performed within 18 hours of suspected birth asphyxia, is associated with adverse outcome, and that increased lactate can be used to predict adverse outcome. (nih.gov)
Magnetic resonance imaging of the brain at ages 11 and 14 years showed extensive abnormalities of the cerebral white matter. (mhmedical.com)

The purpose of this investigation was to 1) compare the performance of proton nuclear magnetic resonance spectroscopy to gas chromatography head-space analysis in the measurement of serum isopropanol and its metabolite, acetone, obtained during a simulated overdose, and 2) compare pharmacokinetic parameters obtained using the two analytical techniques. (elsevier.com)
Resulting sera were analyzed by gas chromatography head-space analysis and proton nuclear magnetic resonance spectroscopy for determination of isopropanol and acetone concentrations. (elsevier.com)
A correlation between concentrations quantitated by gas chromatography head-space analysis versus proton nuclear magnetic resonance spectroscopy was determined using linear regression. (elsevier.com)
Proton nuclear magnetic resonance spectroscopy can be used to rapidly quantitate serum isopropanol and acetone concentrations in the same sample when gas chromatography head-space analysis is unavailable. (elsevier.com)
Also, proton nuclear magnetic resonance spectroscopy can be used to follow serial serum concentrations during an ingestion for the purpose of pharmacokinetic analysis. (elsevier.com)

MCT1 Inhibitor AZD3965 Increases Mitochondrial Metabolism, Facilitating Combination Therapy and Noninvasive Magnetic Resonance Spectroscopy. (icr.ac.uk)

Magnetic resonance spectroscopy (MRS) was used to quantify concentrations of NAA, glutamate and other brain metabolites in globus pallidus, putamen, thalamus, and frontal cortex from a well-established cohort of 10 male Mn-exposed smelters and 10 male age-matched control subjects. (uzh.ch)
Using proton magnetic resonance spectroscopy (MRS), we have demonstrated regional abnormalities in cortical γ-aminobutyric acid (GABA) and glutamate in medication-free recovered depressed patients. (mdx.ac.uk)

Although techniques such as proton magnetic resonance spectroscopy (MRS) have yielded insight into the workings of the brain, these techniques are mostly restricted to single voxels (to obtain relatively large signal over a homogeneous area of brain) and thus to small areas of the brain that sometimes may not be relevant to psychiatric illness. (robbreport.com)
Multivoxel spectroscopy is able to identify the metabolite profile in brain regions but suffers from long data acquisition times. (robbreport.com)
Proton magnetic resonance spectroscopy (¹H MRS) is a well-established technique for quantifying the brain regional biochemistry in vivo. (mpg.de)
the Experts' Working Group on Magnetic resonance spectroscopy in the rodent brain 2021, ' Magnetic resonance spectroscopy in the rodent brain: Experts' consensus recommendations ', NMR in Biomedicine , vol. 34, no. 5, e4325. (elsevier.com)
Using magnetic resonance spectroscopy, researchers at the University of New South Wales Brain Sciences (Sydney, Australia) recently showed that the brain is damaged more severely by obstructive sleep apnea (OSA) and snoring than previously thought. (spectroscopyonline.com)
Magnetic resonance spectroscopy (MRS) provides a tool to measure the concentration of chemicals in regions of interest (ROIs) of the brain. (medscape.com)
In vivo magnetic resonance spectroscopy (MRS) was used to determine the relationship between serum and brain lithium levels in bipolar patients (n = 25). (elsevier.com)
Magnetic Resonance Spectroscopy (MRS) is a unique technique that can directly assess the concentration of various biochemical metabolites in the brain. (ias.ac.in)
Effects of the potential lithium-mimetic, ebselen, on brain neurochemistry: a magnetic resonance spectroscopy study at 7 tesla. (ox.ac.uk)
In addition, the property of Mn as Magnetic Resonance Imaging (MRI) contrast agent may be used to study Mn deposition in the human brain. (cdc.gov)
Magnetic resonance imaging of the brain showed diffuse white matter lesions. (cdc.gov)
Magnetic resonance imaging of the brain of a 46-year-old immunocompromised woman with central nervous system brucellosis granuloma and white matter disease, Saudi Arabia. (cdc.gov)
Magnetic resonance imaging (MRI) of the brain showed diffuse T2/fluid-attenuated inversion recovery hyperintense white matter lesions involving the right frontal, parietal and temporal lobes ( Figure 1 ). (cdc.gov)
These paradigms are Diffusion Tensor Imaging (DTI), Magnetization Transfer Imaging (MTI), T2-Relaxography, and Magnetic Resonance Spectroscopy (MRS). Studies examining brain development during childhood and adulthood as well as studies of the effects of aging are discussed. (umn.edu)
A longitudinal proton magnetic resonance spectroscopy study of mild traumatic brain injury. (bvsalud.org)
We use functional magnetic resonance imaging (fMRI) of the brain and the spinal cord, functional near infrared spectroscopy (fNIRS), behavioral measures and psychophysics to understand how humans differentiate between "self" and "other" - and what happens if this differentiation is altered. (liu.se)
This can lead to long-chain fatty alcohol accumulation as demonstrated in the brain with proton magnetic resonance spectroscopy. (arizona.edu)
APOE genotype modulates proton magnetic resonance spectroscopy metabolites in the aging brain. (cdc.gov)
Functional Magnetic Resonance Imaging (fMRI) is the most widely used technique for investigating the living, functioning human brain as people perform tasks and experience mental states. (coursera.org)

This thesis concerns the application of nmr spectroscopy to the study and definition of both the time dependent and the time independent three dimensional geometries of organic molecules in solution. (bl.uk)
Sleep specialists from the Woolcock Institute at Sydney University used magnetic resonance spectroscopy to study a dozen male patients who had severe, untreated OSA. (spectroscopyonline.com)
To study the effects of starvation on cellular energetics and water distribution in skeletal muscle, a novel 31 P magnetic resonance technique ( 31 P MRS) was developed to measure water compartments. (utmb.edu)
This study is comparing how well two types of magnetic resonance imaging (MRI) scanners can detect different types of heart diseases, such as coronary heart disease, heart failure, congenital heart disease, and heart valve disease. (nih.gov)
Participants in the study will complete physical activities and then undergo magnetic resonance imaging (MRI) to look for changes in the chemicals the body uses for energy. (nih.gov)
Several newer magnetic resonance imaging (MRI) techniques are increasingly being applied to the study of white matter development and pathology across the lifespan. (umn.edu)
Wozniak, JR & Lim, KO 2006, ' Advances in white matter imaging: A review of in vivo magnetic resonance methodologies and their applicability to the study of development and aging ', Neuroscience and Biobehavioral Reviews , vol. 30, no. 6, pp. 762-774. (umn.edu)
Objective This cross-sectional study examined whether contrasting distributions of nuclear magnetic resonance (NMR)-measured lipoproteins contribute to differences in the prevalence of subclinical atherosclerosis measured using coronary artery calcium (CAC) between the two groups of middle-aged males: the US-residing Caucasian (US-White) and Japan-residing Japanese (Japanese). (elsevier.com)
Applications of Fourier Transform Infrared Spectroscopy to Study Cotton Fibers Noureddine Abidi, Eric Hequet and Luis Cabrales Texas Tech University USA 1. (cliftonautotinting.com)
Application of fourier transform infrared spectroscopy to the study of semicrystalline polymers: Poly(ethylene terephthalate) L. D'esposito Department of Macromolecular Science, Case Western Reserve University, Cleveland, Ohio 44106 Fourier transform deﬁned There you have it. (cliftonautotinting.com)
This thesis describes a study of subsurface magnetic impurities using low-temperature scanning tunnelling spectroscopy. (uni-goettingen.de)

To characterize metabolic abnormalities in the muscles of children with the juvenile variant of dermatomyositis (JDM) by the use of noninvasive P-31 magnetic resonance spectroscopy (MRS). Methods. (elsevier.com)
This book is intended to serve as an up-to-date reference source for those familiar with chromatography/Fourier transform infrared spectroscopy (FT-IR) methods and as an introduction to techniques and applications for those interested in future uses for chromatography/FT-IR. (cliftonautotinting.com)

The products can be separated and purified by silica gel column chromatography, and the structure can be analyzed by mass spectroscopy and nuclear magnetic resonance spectroscopy. (pku.edu.cn)

Other, more advanced, two-dimensional techniques such as rotational echo double resonance can be used to measure distances (1). (pharmtech.com)

For example, new 3-dimensional (3D) spectroscopy techniques allow for improved correlation of metabolite profiles with specific regions of interest in anatomical tumor images, which can be useful in characterizing and treating heterogeneous tumors that appear structurally homogeneous. (elsevier.com)

Most often, 13 C NMR spectroscopy is used, but many other nuclei ( e.g., 19 F, 15 N, 23 Na, 31 P, 17 O, or 2 H) can be used, depending on what will be studied. (pharmtech.com)
Here a magnetic field is used to create energy levels for magnetic nuclei present in a molecule. (coursera.org)
And that's the frequencies [COUGH] at which you observe magnetic resonance transitions from nuclei. (coursera.org)

Metabolic abnormalities in developmental dyslexia detected by 1H magnetic resonance spectroscopy. (ox.ac.uk)

Background Processing and quantitative analysis of magnetic resonance spectroscopy (MRS) data are far from standardized and require interfacing with third-party software. (biorxiv.org)
Moreover, SSNMR spectroscopy is quantitative and selective. (pharmtech.com)
Because NMR spectroscopy is inherently a quantitative technique ( i.e., signal intensity is relative to the number of nuclear sites at that specific resonance frequency), SSNMR spectroscopy also can provide quantitative information if done properly, as will be discussed later in this article. (pharmtech.com)

Resting-state functional MRI, diffusion tensor imaging and magnetic resonance spectroscopy data were acquired. (bmj.com)
This course covers the design, acquisition, and analysis of Functional Magnetic Resonance Imaging (fMRI) data, including psychological inference, MR Physics, K Space, experimental design, pre-processing of fMRI data, as well as Generalized Linear Models (GLM's). (coursera.org)

Above copied from OECD (2019), PISA 2018 Results (Volume II): Where All Students Can Succeed, PISA, OECD Publishing, Paris, https://doi.org/10.1787/b5fd1b8f-en . (philippinesbasiceducation.us)

It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING). (musc.edu)

Specifically, 3D MRSI-based overlays provide coisual cues and location information during neurosurgery, enabling a progressive new form of online spectroscopy-guided neuronavigation. (elsevier.com)

Guanosine tetraphosphate, recently discovered to mediate the regulatory relationship between protein synthesis and RNA accumulation in various bacteria, has been synthesized in vitro in large quantities and analyzed by natural abundance 13 C nuclear magnetic resonance spectroscopy in order to confirm its structure and establish the positions of phosphate attachment. (umn.edu)
Nuclear magnetic resonance studies of amino acids and proteins. (eurekamag.com)
The technique has the advantage over 13C nuclear magnetic resonance (NMR) that no assumptions about bond lengths (which appear to the sixth power in 13C relaxation studies) or relaxation mechanisms need to be made, since relaxation will always be quadrupolar, even for aromatic residues at high field. (eurekamag.com)
Nuclear Magnetic Resonance Spectroscopy. (harvard.edu)
An Introduction to biomedical nuclear magnetic resonance / edited by Steffen B. Petersen, Robert N. Muller, Peter A. Rinck. (who.int)
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These are UV/Visible , Infra-red (IR) and Nuclear Magnetic Resonance (NMR) spectroscopies. (coursera.org)
This week we concentrate on Nuclear Magnetic Resonance (NMR) spectroscopy. (coursera.org)
So we're talking about nuclear magnetic resonance, NMR spectroscopy. (coursera.org)
Can NMR (Nuclear Magnetic Resonance) spectroscopy serve as a diagnostic tool for Rheumatoid Arthritis? (peertechzpublications.com)
NMR (nuclear magnetic resonance) spectroscopy based metabolomics studies of serum, urine and synovial fluid of RA were performed. (peertechzpublications.com)
So, our question "Can NMR (Nuclear Magnetic Resonance) spectroscopy serve as a diagnostic tool for rheumatoid arthritis? (peertechzpublications.com)
DXA was used to assess body composition, graded treadmill exercise test to measure cardiovascular fitness, oral glucose tolerance to measure S I , nuclear magnetic resonance spectroscopy to assess lipoprotein particles, and automatic auscultation to measure blood pressure. (lww.com)
An experimentally determined model of the single finger is proposed that is consistent with circular dichroism, one- and two-dimensional nuclear magnetic resonance, and visual spectroscopy of the single-finger peptide reconstituted in the presence of zinc. (embl.de)
The vision of scanning the human body without radiation came to Dr. Damadian in the late 1960s, he said, when he was working on nuclear magnetic resonance spectroscopy - which, until then, had been used to identify the chemical makeup of the contents of a test tube - at Downstate Medical Center (now SUNY Downstate Health Sciences University) in Brooklyn. (artdiamondblog.com)
It took 18 months to build the first M.R.I., originally known as a nuclear magnetic resonance scanner, or N.M.R. Its first scan, on July 3, 1977, was of Lawrence Minkoff, one of Dr. Damadian's assistants - a vivid and colorful image of his heart, lungs, aorta, cardiac chamber and chest wall. (artdiamondblog.com)
The structures of both the monomer and the soluble polymer were elucidated by nuclear magnetic resonance (H-1 and C-13 NMR) and Fourier transform infrared (FTIR) spectroscopy. (metu.edu.tr)
The resultant monomer was characterized by Nuclear Magnetic Resonance (H-1-NMR). (metu.edu.tr)
The specific molecular interactions of the WHWTYYW peptide with cellohexaose were examined using nuclear magnetic resonance (NMR). (elsevier.com)

B10) Dr. Raymond Damadian, who built the first magnetic resonance imaging scanner, which revolutionized doctors' ability to diagnose cancer and other illnesses - but who, to his dismay, saw the Nobel Prize for the science behind it go to two others - died on Aug. 3 [2022] at his home in Woodbury, N.Y. (artdiamondblog.com)

Edited Magnetic Resonance Spectroscopy (MRS) offers the unique possibility to measure gamma-aminobutyric acid (GABA) and other neurometabolites in vivo non-invasively in workers exposed to Mn. (cdc.gov)

The purposes of this thesis are: (a) to establish the conceptual background to both nmr spectroscopy and conformational analysis and hence to relate the two fields, (b) to review in varying depth the published results in those areas of chemistry which have been ventured upon in the current research and (c) to present the results and conclus: :ions of the current studies. (bl.uk)
Upon this basis and upon results published for studies of aziridine inversion barriers, an estimate of the resonance energy in dimethylaniline is suggested at 10+/-1 kcal. (bl.uk)

This article discusses the advantages and disadvantages of using solid-state NMR spectroscopy for the analysis of pharmaceutical solids. (pharmtech.com)

Background: Applications in clinical medicine can benefit from fusion of spectroscopy data with anatomical imagery. (elsevier.com)
But in 2003, when Dr. Lauterbur and Dr. Mansfield won the Nobel Prize in Medicine for their contributions to the science of magnetic resonance imaging, Dr. Damadian was enraged. (artdiamondblog.com)

For amorphous materials, SSNMR spectroscopy can be used to examine the degree of disorder because various processing techniques ( e.g., lyophilization, spray drying, melt-quench, cryomilling) can vary the overall degree of disorder in the sample. (pharmtech.com)

We conducted a computer-based literature search using the Pubmed database with 'magnetic resonance spectroscopy', 'MRS', 'depression', and 'major depressive disorder' as the key words, supplemented by a manual search of bibliographic cross-referencing. (ias.ac.in)

Identification of compounds and chemical groups are based on the magnetic environment surrounding the hydrogen atoms in these groups. (polyhedronlab.com)

Working with rats, he discovered that when tissues were placed in a magnetic field and hit with a pulse of radio waves, cancerous ones emitted distinctly different radio signals than healthy ones. (artdiamondblog.com)

Anatomy18

Organisms5

Diseases21

Chemicals and Drugs84

Analytical, Diagnostic and Therapeutic Techniques and Equipment66

Psychiatry and Psychology7

Phenomena and Processes46

Disciplines and Occupations7

Anthropology, Education, Sociology and Social Phenomena2

Technology, Industry, Agriculture3

Information Science11

Health Care15

The interaction of rhodium(II) carboxylates with enzymes. (1/24698)

Prodigious substrate specificity of AAC(6')-APH(2"), an aminoglycoside antibiotic resistance determinant in enterococci and staphylococci. (2/24698)

Single atom modification (O-->S) of tRNA confers ribosome binding. (3/24698)

Molecular dynamics studies of U1A-RNA complexes. (4/24698)

An examination of coaxial stacking of helical stems in a pseudoknot motif: the gene 32 messenger RNA pseudoknot of bacteriophage T2. (5/24698)

Purinogen is not an endogenous substrate used in endothelial cells during substrate deprivation. (6/24698)

Accumulation of astaxanthin all-E, 9Z and 13Z geometrical isomers and 3 and 3' RS optical isomers in rainbow trout (Oncorhynchus mykiss) is selective. (7/24698)

Biophysical characterization of the structure of the amino-terminal region of gp41 of HIV-1. Implications on viral fusion mechanism. (8/24698)

Magnetic Resonance Spectroscopy

Magnetic Resonance Imaging

Creatine

Phosphocreatine

Choline

Aspartic Acid

Protons

Electron Spin Resonance Spectroscopy

Nuclear Magnetic Resonance, Biomolecular

Phosphorus

Brain

Inositol

Phosphorus Isotopes

Magnetic Resonance Angiography

Carbon Isotopes

Energy Metabolism

Fluorine

Phosphates

Magnetic Resonance Imaging, Cine

Glutamine

Hydrogen-Ion Concentration

Brain Chemistry

Lactic Acid

Glutamic Acid

Spectroscopy, Near-Infrared

Diffusion Magnetic Resonance Imaging

Spectrum Analysis

Phosphorylcholine

Protein Conformation

Models, Molecular

Adenosine Triphosphate

Contrast Media

Hydrogen

Spectrophotometry, Infrared

Muscle, Skeletal

Reproducibility of Results

Image Processing, Computer-Assisted

Surface Plasmon Resonance

Oxygen

Solutions

Deuterium

Brain Mapping

Mass Spectrometry

Glycerylphosphorylcholine

Molecular Sequence Data

Lactates

Sensitivity and Specificity

Metabolomics

Carbohydrate Sequence

Spin Labels

Brain Neoplasms

Kinetics

Time Factors

Protein Structure, Secondary

Circular Dichroism

Brain Diseases

Gyrus Cinguli

Spectrum Analysis, Raman

Water

Molecular Structure

Occipital Lobe

Neurochemistry

Gadolinium DTPA

Amino Acid Sequence

Molecular Conformation

Oxidation-Reduction

Carbohydrate Conformation

Gadolinium

Chemistry

Metabolome

Chromatography, High Pressure Liquid

Chemical Phenomena

Reference Values

Glucose

Protein Binding

Imaging, Three-Dimensional

Frontal Lobe

Image Interpretation, Computer-Assisted

Spectrometry, Mass, Fast Atom Bombardment

Nitrogen Isotopes