A circumscribed stable malformation of the skin and occasionally of the oral mucosa, which is not due to external causes and therefore presumed to be of hereditary origin.
A macular lesion on the side of the FACE, involving the CONJUNCTIVA and EYELIDS, as well as the adjacent facial skin, SCLERA; OCULOMOTOR MUSCLES; and PERIOSTEUM. Histological features vary from those of a MONGOLIAN SPOT to those of a BLUE NEVUS.
A syndrome characterized by lesions occurring on the face, scalp, or neck which consist of congenital hypoplastic malformations of cutaneous structures and which over time undergo verrucous hyperplasia. Additionally it is associated with neurological symptoms and skeletal, ophthalmological, urogenital, and cardiovascular abnormalities.
Light brown pigmented macules associated with NEUROFIBROMATOSIS and Albright's syndrome (see FIBROUS DYSPLASIA, POLYOSTOTIC).
Excessive pigmentation of the skin, usually as a result of increased epidermal or dermal melanin pigmentation, hypermelanosis. Hyperpigmentation can be localized or generalized. The condition may arise from exposure to light, chemicals or other substances, or from a primary metabolic imbalance.
Clinically atypical nevi (usually exceeding 5 mm in diameter and having variable pigmentation and ill defined borders) with an increased risk for development of non-familial cutaneous malignant melanoma. Biopsies show melanocytic dysplasia. Nevi are clinically and histologically identical to the precursor lesions for melanoma in the B-K mole syndrome. (Stedman, 25th ed)
Disorders of increased melanin pigmentation that develop without preceding inflammatory disease.
A condition caused by a deficiency or a loss of melanin pigmentation in the epidermis, also known as hypomelanosis. Hypopigmentation can be localized or generalized, and may result from genetic defects, trauma, inflammation, or infections.
A nevus in which nests of melanocytes are found in the dermis, but not at the epidermal-dermal junction. Benign pigmented nevi in adults are most commonly intradermal. (Stedman, 25th ed)
A benign compound nevus occurring most often in children before puberty, composed of spindle and epithelioid cells located mainly in the dermis, sometimes in association with large atypical cells and multinucleate cells, and having a close histopathological resemblance to malignant melanoma. The tumor presents as a smooth to slightly scaly, round to oval, raised, firm papule or nodule, ranging in color from pink-tan to purplish red, often with surface telangiectasia. (Dorland, 27th ed)
Tumors or cancer of the SKIN.
A group of disorders characterized by an autosomal dominant pattern of inheritance with high rates of spontaneous mutation and multiple neurofibromas or neurilemmomas. NEUROFIBROMATOSIS 1 (generalized neurofibromatosis) accounts for approximately 95% of cases, although multiple additional subtypes (e.g., NEUROFIBROMATOSIS 2, neurofibromatosis 3, etc.) have been described. (From Neurochirurgie 1998 Nov;44(4):267-72)
Diseases of the skin with a genetic component, usually the result of various inborn errors of metabolism.
Autosomal dominant, congenital disorder characterized by localized hypomelanosis of the skin and hair. The most familiar feature is a white forelock presenting in 80 to 90 percent of the patients. The underlying defect is possibly related to the differentiation and migration of melanoblasts, as well as to defective development of the neural crest (neurocristopathy). Piebaldism may be closely related to WAARDENBURG SYNDROME.
A permanent ashen-gray discoloration of the skin, conjunctiva, and internal organs resulting from long-continued use of silver salts. (Dorland, 27th ed)
A benign skin lesion characterized by a zone of depigmentation surrounding the nevus.
A cellular subtype of malignant melanoma. It is a pigmented lesion composed of melanocytes occurring on sun-exposed skin, usually the face and neck. The melanocytes are commonly multinucleated with a "starburst" appearance. It is considered by many to be the in situ phase of lentigo maligna melanoma.
A disorder consisting of areas of macular depigmentation, commonly on extensor aspects of extremities, on the face or neck, and in skin folds. Age of onset is often in young adulthood and the condition tends to progress gradually with lesions enlarging and extending until a quiescent state is reached.
A neoplasm composed of squamous or epidermal cells.
Conditions in which there is histological damage to the lower epidermis along with a grouped chronic inflammatory infiltrate in the papillary dermis disturbing the interface between the epidermis and dermis. LICHEN PLANUS is the prototype of all lichenoid eruptions. (From Rook et al., Textbook of Dermatology, 4th ed, p398)
Hereditary disorder consisting of multiple basal cell carcinomas, odontogenic keratocysts, and multiple skeletal defects, e.g., frontal and temporoparietal bossing, bifurcated and splayed ribs, kyphoscoliosis, fusion of vertebrae, and cervicothoracic spina bifida. Genetic transmission is autosomal dominant.
A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
FIBROUS DYSPLASIA OF BONE affecting several bones. When melanotic pigmentation (CAFE-AU-LAIT SPOTS) and multiple endocrine hyperfunction are additionally associated it is referred to as Albright syndrome.
A nevus containing melanin. The term is usually restricted to nevocytic nevi (round or oval collections of melanin-containing nevus cells occurring at the dermoepidermal junction of the skin or in the dermis proper) or moles, but may be applied to other pigmented nevi.
Tumor suppressor genes located on the long arm of human chromosome 17 in the region 17q11.2. Mutation of these genes is thought to cause NEUROFIBROMATOSIS 1, Watson syndrome, and LEOPARD syndrome.
An autosomal dominant inherited disorder (with a high frequency of spontaneous mutations) that features developmental changes in the nervous system, muscles, bones, and skin, most notably in tissue derived from the embryonic NEURAL CREST. Multiple hyperpigmented skin lesions and subcutaneous tumors are the hallmark of this disease. Peripheral and central nervous system neoplasms occur frequently, especially OPTIC NERVE GLIOMA and NEUROFIBROSARCOMA. NF1 is caused by mutations which inactivate the NF1 gene (GENES, NEUROFIBROMATOSIS 1) on chromosome 17q. The incidence of learning disabilities is also elevated in this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1014-18) There is overlap of clinical features with NOONAN SYNDROME in a syndrome called neurofibromatosis-Noonan syndrome. Both the PTPN11 and NF1 gene products are involved in the SIGNAL TRANSDUCTION pathway of Ras (RAS PROTEINS).
The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendinous galea aponeurotica; loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL).
Permanent dilation of preexisting blood vessels (CAPILLARIES; ARTERIOLES; VENULES) creating small focal red lesions, most commonly in the skin or mucous membranes. It is characterized by the prominence of skin blood vessels, such as vascular spiders.
A noninvasive technique that enables direct microscopic examination of the surface and architecture of the SKIN.
Autosomal dominant neurocutaneous syndrome classically characterized by MENTAL RETARDATION; EPILEPSY; and skin lesions (e.g., adenoma sebaceum and hypomelanotic macules). There is, however, considerable heterogeneity in the neurologic manifestations. It is also associated with cortical tuber and HAMARTOMAS formation throughout the body, especially the heart, kidneys, and eyes. Mutations in two loci TSC1 and TSC2 that encode hamartin and tuberin, respectively, are associated with the disease.
Tumors of the iris characterized by increased pigmentation of melanocytes. Iris nevi are composed of proliferated melanocytes and are associated with neurofibromatosis and malignant melanoma of the choroid and ciliary body. Malignant melanoma of the iris often originates from preexisting nevi.
An inflammatory, pruritic disease of the skin and mucous membranes, which can be either generalized or localized. It is characterized by distinctive purplish, flat-topped papules having a predilection for the trunk and flexor surfaces. The lesions may be discrete or coalesce to form plaques. Histologically, there is a "saw-tooth" pattern of epidermal hyperplasia and vacuolar alteration of the basal layer of the epidermis along with an intense upper dermal inflammatory infiltrate composed predominantly of T-cells. Etiology is unknown.
A focal malformation resembling a neoplasm, composed of an overgrowth of mature cells and tissues that normally occur in the affected area.
Color of hair or fur.
Mammalian pigment cells that produce MELANINS, pigments found mainly in the EPIDERMIS, but also in the eyes and the hair, by a process called melanogenesis. Coloration can be altered by the number of melanocytes or the amount of pigment produced and stored in the organelles called MELANOSOMES. The large non-mammalian melanin-containing cells are called MELANOPHORES.
Small circumscribed melanoses resembling, but differing histologically from, freckles. The concept includes senile lentigo ('liver spots') and nevoid lentigo (nevus spilus, lentigo simplex) and may also occur in association with multiple congenital defects or congenital syndromes (e.g., Peutz-Jeghers syndrome).
The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
Tumors of the choroid; most common intraocular tumors are malignant melanomas of the choroid. These usually occur after puberty and increase in incidence with advancing age. Most malignant melanomas of the uveal tract develop from benign melanomas (nevi).
Irradiation directly from the sun.
A heritable disorder of faulty keratinization characterized by the proliferation of abnormal clones of KERATINOCYTES and lesions showing varying atrophic patches surrounded by an elevated, keratotic border. These keratotic lesions can progress to overt cutaneous neoplasm. Several clinical variants are recognized, including porokeratosis of Mibelli, linear porokeratosis, disseminated superficial actinic porokeratosis, palmoplantar porokeratosis, and punctate porokeratosis.
Coloration of the skin.
An injury to the skin causing erythema, tenderness, and sometimes blistering and resulting from excessive exposure to the sun. The reaction is produced by the ultraviolet radiation in sunlight.
Tumors or cancer of the CONJUNCTIVA.
Simple sweat glands that secrete sweat directly onto the SKIN.
A vascular anomaly due to proliferation of BLOOD VESSELS that forms a tumor-like mass. The common types involve CAPILLARIES and VEINS. It can occur anywhere in the body but is most frequently noticed in the SKIN and SUBCUTANEOUS TISSUE. (from Stedman, 27th ed, 2000)
Neoplasms composed of sebaceous or sweat gland tissue or tissue of other skin appendages. The concept does not refer to neoplasms located in the sebaceous or sweat glands or in the other skin appendages.
The record of descent or ancestry, particularly of a particular condition or trait, indicating individual family members, their relationships, and their status with respect to the trait or condition.
Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.
A non-inherited congenital condition with vascular and neurological abnormalities. It is characterized by facial vascular nevi (PORT-WINE STAIN), and capillary angiomatosis of intracranial membranes (MENINGES; CHOROID). Neurological features include EPILEPSY; cognitive deficits; GLAUCOMA; and visual defects.
Color of the iris.
General disorders of the sclera or white of the eye. They may include anatomic, embryologic, degenerative, or pigmentation defects.
A malignant skin neoplasm that seldom metastasizes but has potentialities for local invasion and destruction. Clinically it is divided into types: nodular, cicatricial, morphaic, and erythematoid (pagetoid). They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck area and the remaining 15% on the trunk and limbs. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1471)
Hamartoneoplastic malformation syndrome of uncertain etiology characterized by partial GIGANTISM of the hands and/or feet, asymmetry of the limbs, plantar hyperplasia, hemangiomas (HEMANGIOMA), lipomas (LIPOMA), lymphangiomas (LYMPHANGIOMA), epidermal NEVI; MACROCEPHALY; cranial HYPEROSTOSIS, and long-bone overgrowth. Joseph Merrick, the so-called "elephant man", apparently suffered from Proteus syndrome and not NEUROFIBROMATOSIS, a disorder with similar characteristics.
A characteristic symptom complex.
A benign, non-neoplastic, usually self-limiting epithelial lesion closely resembling squamous cell carcinoma clinically and histopathologically. It occurs in solitary, multiple, and eruptive forms. The solitary and multiple forms occur on sunlight exposed areas and are identical histologically; they affect primarily white males. The eruptive form usually involves both sexes and appears as a generalized papular eruption.
A form of pigmented nevus showing intense melanocytic activity around the dermo-epidermal junction. Large numbers of spindle-shaped melanocytes proliferate downward toward the dermis and usually a large amount of pigment is present. It was first described in 1976 and the bulk of patients reported have been young females with the lesions presenting on the thighs. (From Rook et al., Textbook of Dermatology, 4th ed, 1992, p185)
Diseases, dysfunctions, or disorders of or located in the iris.
Tumors or cancer of the EYE.
A bluish-gray to gray-brown benign, melanocytic nevus found usually in the LUMBOSACRAL REGION of dark-skinned people, especially those of East Asian ancestry. It is usually congenital or appears shortly after birth, and disappears in childhood.
An autosomal dominant disorder that is manifested by thickened spongiform ORAL MUCOSA with a white opalescent tint. Other MUCOSAL TISSUE may also be involved mucosa found in the VAGINA; RECTUM, and NASAL CAVITY may be similarly involved. This form of LEUKOKERATOSIS can be caused by a mutation in the gene for KERATIN 4 and is not considered a PRENEOPLASTIC CONDITION.
Other presentation of oral nevi includes: Blue nevus, junctional nevus and compound nevus. Melanotic macules can be found on ... Oral nevi or oral melanocytic nevi, are result of benign proliferations of nevus cells present either in the epithelial layer, ... malanotic macules (22.9%) and nevus (20.5%). List of cutaneous conditions Melanocytic oral lesion White sponge nevus Lenkiewicz ... Most commonly seen presentation of oral nevi are intramucosal nevi, these are dome shaped brown papules accounting for 64% of ...
... hemangiomatosis and glans penis macules. Proteus syndrome is characterised by nevi, asymmetric overgrowth of various body parts ... Tromberg J, Bauer B, Benvenuto-Andrade C, Marghoob AA (2005). "Congenital melanocytic nevi needing treatment". Dermatol Ther. ... Marghoob AA, Borrego JP, Halpern AC (December 2007). "Congenital melanocytic nevi: treatment modalities and management options ...
Birthmark Nevus List of cutaneous conditions List of conditions associated with café au lait macules Plensdorf S, Martinez J ( ... Café au lait spots, or café au lait macules, are flat, hyperpigmented birthmarks. The name café au lait is French for "coffee ... Café au lait spots can arise from diverse and unrelated causes: Ataxia-telangiectasia Basal cell nevus syndrome Benign ...
Macules: Nevus flammeus Angioma serpiginosum Telangiectasia macularis eruptive perstans EAH is a benign hamartoma and if there ... EAH exists on a spectrum of cutaneous tumors that include eccrine nevus, mucinous eccrine nevus and EAH. Each diagnostic ... Blue rubber bleb nevus Sudoriparous angioma - Another rare, benign tumor where eccrine glands of normal number are seen lying ... Vascular malformations: Eccrine nevus - Characterized histopathologically by an increase in eccrine structures but not ...
... café au lait macules, seborrheic keratosis, Civatte's poikiloderma, acquired bilateral nevus of ota-like macules (Hori's nevus ... The symptoms of melasma are dark, irregular, well-demarcated, hyperpigmented macules to patches. These patches often develop ... Additionally, it should not be confused with phytophotodermatosis, pellagra, endogenous phototoxicity, nevus of Ota, ...
Lentigo simplex Solar lentigo Café au lait macule Ink-spot lentigo Mucosal melanotic macule Mongolian spot (dermal ... Pigmented spindle cell nevus Spitz nevus Zosteriform lentiginous nevus Congenital melanocytic nevus These nevi are often ... Basal cell nevus syndrome Blue rubber bleb nevus syndrome Dysplastic nevus syndrome Epidermal nevus syndrome Linear nevus ... Becker's nevus Blue nevus (rarely congenital): A classic blue nevus is usually smaller than 1 cm, flat, and blue-black in color ...
... is a congenital disorder characterized by macules of varying size and shape that are paler than the surrounding ... Since the histopathology of nevus anemicus is normal, nevus anemicus is a pharmacologic nevus and not an anatomic one. In most ... Nevus anemicus. J Am Acad Dermatol 1986;14:628-32.. Requena L, Sangueza OP. Cutaneous vascular anomalies. Part 1. Hamartomas, ... Results of a skin biopsy would be interpreted as normal and only physiological testing can reveal the nevus in contrast to ...
... is a skin lesion that presents as a light brown or tan macule, speckled with smaller, darker macules or papules. Prevalence is ... 1985). "Prevalence of congenital-nevus-like nevi, nevi spili, and café au lait spots". Archives of Dermatology. 121 (6): 766-9 ... Nevus spilus (also known as speckled lentiginous nevus and zosteriform lentiginous nevus) ... Phakomatosis pigmentokeratotica Zosteriform speckled lentiginous nevus Skin lesion List of cutaneous conditions Rapini, Ronald ...
... is a cutaneous condition characterized by a diffusely gray-blue area that may have superimposed darker macules. A blue nevus of ... Blue nevus Cellular blue nevus Epithelioid blue nevus Malignant blue nevus List of cutaneous conditions List of genes mutated ... Blue nevus (also known as "blue neuronevus", "dermal melanocytoma", "nevus coeruleus" and "nevus bleu") is a type of ... some melanomas can look like a blue nevus. Blue nevi may be divided into the following types: A patch blue nevus (also known as ...
... (also known as "Acquired bilateral nevus of Ota-like macules") is a cutaneous condition characterized by multiple ... brown-gray to brown-blue macules, primarily in the malar region of the face. Nevus of Ota List of cutaneous conditions Rapini, ...
A pigmented spindle cell nevus is a skin condition characterized by a dark brown to black macule or papule, usually less than 6 ... Jun 1975). "Common and uncommon melanocytic nevi and borderline melanomas". Semin Oncol. 2 (2): 119-47. PMID 1234372. v t e. ... Partial unilateral lentiginosis List of cutaneous conditions Spitz nevus Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph ...
Vasospastic macules are a skin condition due to localized vasoconstriction and are seen most often in young women. Nevus ...
Congenital melanocytic nevus is a type of melanocytic nevus, the medical term for what is colloquially called a "mole", found ... Café au lait spot macules may occur anywhere on the body. They are most commonly oval in shape and light brown, or milk coffee ... Port-wine stains, also known as nevus flammeus and sometimes mistaken for strawberry marks, are present at birth and range from ... Several birthmark types are part of the group of skin lesions known as nevi or naevi, which is Latin for "birthmarks". ...
Initial skin findings include red-purple, dusky, flat spots known as macules that start on the trunk and spread out from there ... Skin manifestations can include scarring, eruptive melanocytic nevi, vulvovaginal stenosis, and dyspareunia. The epithelium of ...
Oculodermal melanocytosis (nevus of Ota) Pigment dispersion syndrome - a condition characterized by loss of pigmentation from ... of melanocyte development characterized by a white forelock and multiple symmetrical hypopigmented or depigmented macules. ... A stimulation of melanin synthesis within iris melanocytes has been postulated.[medical citation needed] Neoplasm - Nevi and ... a syndrome characterized by a port-wine stain nevus in the distribution of the trigeminal nerve, ipsilateral leptomeningeal ...
Sutton nevus) Hori's nevus (acquired bilateral nevus of Ota-like macules) Inherited patterned lentiginosis in black persons Ink ... comedo nevus) Nevus comedonicus syndrome Nevus sebaceous (nevus sebaceous of Jadassohn, organoid nevus) Nevus unius lateris ... Benign melanocytic nevus (banal nevus, common acquired melanocytic nevus, mole, nevocellular nevus, nevocytic nevus) Blue nevus ... atypical nevus, B-K mole, Clark's nevus, dysplastic melanocytic nevus, nevus with architectural disorder) Dysplastic nevus ...
It is painless, and appears as a blue-black or grey discolored macule on the surface of the mucosa. The borders of the tattoo ... If necessary, the diagnosis can be confirmed histologically by excisional biopsy, which excludes nevi and melanomas. If a ...
... one or a few scattered macules in one area, most common in children Acrofacial vitiligo: fingers and periorificial areas ... Pityriasis alba Tuberculoid leprosy Postinflammatory hypopigmentation Tinea versicolor Halo nevus Albinism Piebaldism ...
Vasospastic macule. *Woronoff's ring. *Nevus anemicus. Ungrouped. *Nevus depigmentosus. *Postinflammatory hypopigmentation. * ...
Vasospastic macule. *Woronoff's ring. *Nevus anemicus. Ungrouped. *Nevus depigmentosus. *Postinflammatory hypopigmentation. * ...
Vasospastic macule. *Woronoff's ring. *Nevus anemicus. Ungrouped. *Nevus depigmentosus. *Postinflammatory hypopigmentation. * ...
Focal vitiligo: one or a few scattered macules in one area, most common in children[22] ... Nevus depigmentosus. *Piebaldism. *Pityriasis alba. *Quadrichrome vitiligo, characterized by patches of reduced but not absent ...
This rare genetic disorder is characterized by the development of macules with Hyperpigmentation on the lips and oral mucosa ( ... Nevus depigmentosus. *Postinflammatory hypopigmentation. *Pityriasis alba. *Vagabond's leukomelanoderma. *Yemenite deaf-blind ...
... vitelliform Macules hereditary congenital hypopigmented and hyperpigmented Mad cow disease Madelung's disease Madokoro-Ohdo- ... facial Mental retardation microcephaly unusual facies Mental retardation Mietens-Weber type Mental retardation multiple nevi ...
Lentigines - Reddish-brown to dark brown macules (surface skin lesion) generally occurring in a high number (10,000+) over a ... Zeisler EP, Becker SW (1936). "Generalized lentigo: its relation to systemic nonelevated nevi". Arch Dermatol Syphilol. 33: 109 ...
Café au lait macule. *Ink-spot lentigo. *Mucosal melanotic macule. *Mongolian spot (dermal melanocytosis) ... Linear nevus sebaceous syndrome. Etymology[edit]. A nevus may also be spelled naevus. The plural is nevi or naevi. The word is ... Apocrine nevus. Connective tissue nevi[edit]. These nevi represent abnormalities of collagen in the dermis, the deep layer of ... Zosteriform lentiginous nevus. Congenital[edit]. *Congenital melanocytic nevus *These nevi are often categorized based on size ...
Nevus simplex or vascular stain, which lighten or disappear within the first few years of life. Capillary malformations ... Pyogenic granuloma appears as a red macule that grows rapidly, turns into a papule and eventually becomes pedunculated, being ...
Possibly an acquired white sponge nevus". Archives of Dermatology. 116 (8): 906-8. doi:10.1001/archderm.1980.01640320056014. ... This morphology is characterized by hyperpigmented, dark-brown macules in sun-exposed areas and flexural folds. This is a rare ...
Macules hereditary congenital hypopigmented and hyperpigmented. *Madokoro Ohdo Sonoda syndrome. *Magnesium defect in renal ... Mental retardation multiple nevi. *Mental retardation myopathy short stature endocrine defect. *Mental retardation nasal ...
Aphthous ulcers typically begin as erythematous macules (reddened, flat area of mucosa) which develop into ulcers that are ... Melanocytic nevus. *Melanocytic oral lesion. *Molluscum contagiosum. *Morsicatio buccarum. *Oral cancer *Benign: Squamous cell ...
Macule: A macule is a change in surface color, without elevation or depression and, therefore, nonpalpable, well or ill-defined ... Hair follicle nevus. *Intermittent hair-follicle dystrophy. *Keratosis pilaris atropicans. *Kinking hair ... Patch: A patch is a large macule equal to or greater than either 5 or 10 mm across,[30] depending on one's definition of a ... macules, papules, vesicles), and color (red, blue, brown, black, white, yellow).[10] The diagnosis of many conditions often ...
Nevus simplex or vascular stain, which lighten or disappear within the first few years of life. Capillary malformations ... Pyogenic granuloma appears as a red macule that grows rapidly, turns into a papule and eventually becomes pedunculated, being ...
... hemangiomatosis and glans penis macules.[14][17] Proteus syndrome is characterised by nevi, asymmetric overgrowth of various ... Tromberg J, Bauer B, Benvenuto-Andrade C, Marghoob AA (2005). "Congenital melanocytic nevi needing treatment". Dermatol Ther. ... Marghoob AA, Borrego JP, Halpern AC (December 2007). "Congenital melanocytic nevi: treatment modalities and management options ...
... with the most common lesions being macules, papules, or nodules that are disseminated over most of the body but especially on ... Nevus. *Capillary hemangioma. *Port-wine stain *Nevus flammeus nuchae. Other/ungrouped. *Aplasia cutis congenita ...
... it evolves from a macule to a papule and finally to an erosion or ulcer.[20] Occasionally, multiple lesions may be present (~40 ...
Pigmented AK: Pigmented AKs are rare variants that often present as macules or plaques that are tan to brown in color. They can ... Other nevus. *Nevus unius lateris. *Patch blue nevus. *Unilateral palmoplantar verrucous nevus ... Classic (or common): Classic AKs present as white, scaly macules, papules or plaques of various thickness, often with ... Atrophic: Atrophic AKs lack an overlying scale, and therefore appear as a nonpalpable change in color (or macule). They are ...
The lesions progress initially from red macules to vesicles and lastly to ulcerations which can be 2 - 4 mm in size. ... Melanocytic nevus. *Melanocytic oral lesion. *Molluscum contagiosum. *Morsicatio buccarum. *Oral cancer *Benign: Squamous cell ...
It is characterized by one or more hypopigmented skin macules and patches where skin sensations are lost because of damaged ... macules), raised (papules), or solid elevated areas (nodular).[59] Experiencing sensory loss at the skin lesion is a feature ...
Vasospastic macules are a skin condition due to localized vasoconstriction and are seen most often in young women. Nevus ...
Acquired, Bilateral Nevus of Ota-like Macules (ABNOM) Associated with Otas Nevus: Case Re ... Acquired, Bilateral Nevus of Ota-like Macules (ABNOM) Associated with Otas Nevus: Case Report ... Acquired, bilateral nevus of Ota-like macules (ABNOM) is located bilaterally on the face, appears later in life, is blue-brown ... Adult , Biopsy , Face/pathology , Female , Humans , Melanocytes/cytology , Nevus of Ota/diagnosis , Nevus, Pigmented/diagnosis ...
Acquired bilateral nevus of Ota-like macules (ABNOM) are a common form of hyperpigmentation in Asian populations, characterized ... The Efficacy of a Q-Switched 694-nm Ruby Fractional Laser for Treating Acquired Bilateral Nevus of Ota-Like Macules ... Nevus of Ota , Nevus , Pigmentation , Retrospective Studies , Skin , Skin Pigmentation ... Nevus of Ota / Hyperpigmentation Language: English Journal: Archives of Aesthetic Plastic Surgery Year: 2018 Type: Article ...
Blue nevus. * Oral pigmentation of the gingiva due to amalgam tattoo along with photomicrograph. ...
Helping you find trustworthy answers on Macule , Latest evidence made easy ... Find all the evidence you need on Macule via the Trip Database. ... connective tissue nevus) • Cortical tuber in the brain • ... hyperpigmented macules in a sun-exposed area who is prone to develop basal cell carcinomas. A genetic study revealed a novel ... Small blue macules (maculae cerulae) or red papules - may be seen at feeding sites. Rust-coloured flecks of faecal material ...
Other presentation of oral nevi includes: Blue nevus, junctional nevus and compound nevus. Melanotic macules can be found on ... Oral nevi or oral melanocytic nevi, are result of benign proliferations of nevus cells present either in the epithelial layer, ... malanotic macules (22.9%) and nevus (20.5%). List of cutaneous conditions Melanocytic oral lesion White sponge nevus Lenkiewicz ... Most commonly seen presentation of oral nevi are intramucosal nevi, these are dome shaped brown papules accounting for 64% of ...
Shagreen patch (connective tissue nevus) * Three or more hypomelanotic macules * Nontraumatic ungula or periungual fibromas ...
1. 6+ café au lait macules > 1.5 cm 2. 2+ neurofibromas, or 1 plexiform neurofibroma. 3. Axillary or inguinal freckling 4. ... Dysplastic Nevus Acquired melanocytic proliferation. Round to oval to irregular. Variegation in color- tans, brown, black, reds ...
Blue nevus and its variants.. Botulinum toxin.. Bullous pemphigoid.. Café-au-lait macules.. Candidiasis.. Carcinoma, basal cell ... Nevus of Ota and Ito.. Nevus spilus.. Notalgia paresthetica.. Nutritional diseases.. Oral disease.. Panniculitis. ... Atypical (dysplastic) melanocytic nevus.. Azathioprine.. Bacterial diseases.. Beckers melanosis (nevus).. Behçets disease. ... Common acquired melanocytic nevi.. Confluent and reticulated papillomatosis.. Congenital melanocytic nevus.. Contact dermatitis ...
Dermatopathology Melanocytic tumors Nevi cell melanoma pathology pregnancy skin skin disease Authors and affiliations. *Guido ... The misreading of a section of a malignant melanoma as a nevus, which will then be left untreated, may result in regrowth at ... For example, the evaluation of the so called nevoid (spitzoid) melanoma, Spitzs nevi with conflicting criteria, or some benign ... Whereas, overdiagnosis of Spitzs nevus may be followed by unnecessarily extensive surgery including lymph node dissection and ...
Café au Lait Macule (VisualDX) * Cherry Hemangioma (VisualDX) * Nevus, Congenital Melanocytic (VisualDX) ... Frequently Asked Questions about Congenital Melanocytic Nevus (CMN) (Nevus Outreach, Inc.) * Guide to Understanding Hemangiomas ... Also called: Cafe au lait spot, Hemangioma, Mongolian spot, Nevus, Strawberry mark ...
common mole; melanoma can arise in congenital or atypical moles *intradermal nevi are papular **junctional nevi are flat ...
Nevus spilus. Light brown patch that develops an increasing number of pigmented macules or papules, representing junctional or ... Cafe-au-lait macules (ICD-9 code 709.09). Are You Confident of the Diagnosis?. Solitary cafe-au-lait macules are benign lesions ... Cafe-au-lait macules appear as sharply demarcated hyperpigmented macules or patches. The color ranges from tan to dark brown ... Isolated segmental cafe-au-lait macule in a young child.. Figure 2.. A typical cafe-au-lait macule (homogeneous ...
... of disease information resources and questions answered by our Genetic and Rare Diseases Information Specialists for Macules ... Melanocytic nevus. Beauty mark 0000995 30%-79% of people have these symptoms. ... Macules hereditary congenital hypopigmented and hyperpigmented Title Other Names:. Hereditary congenital hypopigmented and ... PubMed is a searchable database of medical literature and lists journal articles that discuss Macules hereditary congenital ...
This patch contains a variable number of darkly pigmented macules and papules. ... Speckled lentiginous nevus is a patch of hyperpigmentation that can be seen on any area of the body. ... Kopf AW, Levine LJ, Rigel DS, Friedman RJ, Levenstein M. Prevalence of congenital-nevus-like nevi, nevi spili, and cafe au lait ... Speckled lentigenous nevus (nevus spilus). Nordlund JJ, Boissy RE, Hearing VJ, et al, eds. The Pigmentary System. London, ...
... hypopigmented macules), or port-wine stains (nevipammri). When a relevant birthmark is a hyperpigmented nevus, it is nearly ... hypopigmented macules); others were areas of increased pigmentation (hyperpigmented nevi). The birth defects were nearly always ... Figure 1. Hypopigmented macule on chest of an Indian youth who, as a child, said he remembered the life of a man, Maha Ram, who ... Figure 3. Large verrucous epidermal nevus on head of a Thai man who as a child said he remembered the life of his paternal ...
... resources and questions answered by our Genetic and Rare Diseases Information Specialists for Blue rubber bleb nevus syndrome ... Hypermelanotic macule. Hyperpigmented spots 0001034 Intussusception. 0002576 Iron deficiency anemia. 0001891 Pathologic ... Blue rubber bleb nevus syndrome can affect other body organs. as well. Nevi have been reported in the skull, central nervous ... Nevi may also be found in the intestines (particularly the small intestine) in individuals with blue rubber bleb nevus syndrome ...
non palpable change in skin color  Macule-freckles. flat.Circumscribed.localized skin edeme (hive) .elevated nevus  Plaque- ...
Nevus depigmentosus: Congenital hypopigmented macule or plaque. Stable. Does not cross the midline. It is an expression of ... Nevus anemicus: congenital, localized vascular disorder. Hypopigmented macule or plaque. Normal melanocytes and melanin. ... Hypopigmented (off-white) lesions include segmental hypomelanosis, confetti-like hypopigmented macules, ash-leaf macules. ... 3. Other skin diseases with hypopigmented macules or patches:. *. Hypopigmented mycosis fungoides (MF). This is a rare variant ...
Hypomelanotic macules (three or more). Shagreen patch (connective tissue nevus). Multiple retinal nodular hamartomas ... For instance, hypopigmented macules may be present in as many as 1% of all newborns, and are usually of no clinical ... Hypomelanotic macules are not specific to TSC.. Facial angiofibromas (previously termed adenoma sebaceum) are pink or reddish ... The most common skin manifestation of TSC is hypomelanotic macules, previously termed ash leaf lesions. These occur in up to 97 ...
Ephelis, Nevus, Oral Melanocytic Macule. ~Do not vary in color or thickness. ~Not that large. ~Are symmetrical ...
... atypical nevus pattern (≥20 nevi that were ≥2 mm in diameter), plus at least 5 nevi that were 5 mm or greater in diameter (OR, ... 2. Rallis E, Tsibouris P. Pigmented perianal macules. Clin Case Rep 2015; 4: 95-6.. 3. Olsen CM, et al. Risk of melanoma in ... Regarding perianal nevi, Socik et al, including patients aged 23 to 84 years, studied 236 participating patients. Perianal nevi ... In non-Hispanic whites, the presence of at least 1 perianal nevus was significantly associated with history of atypical nevus ...
... hypopigmented macules; and dental pitting. One may also expect to find neurologic signs, with epilepsy resulting from tubers in ... Connective tissue nevus (collagenoma, elastoma, nevus mucinosis). *Depression May Be Associated With Metabolic Syndrome in ... Other connective tissue nevi, such as naevus anelasticus or papular elastorrhexis, are important in the differential. Due to ... When these nevi are involved in complex syndromes such as pseudoxanthoma elasticum (PXE) and familial cutaneous collagenoma, ...
Macules and patches. -flat lesion w. a change in pigmentation. Eg. freckle or nevus. -Papules and Plaque. -solid, elevated ...
Erythrasma(brown), Beckers nevus, lentigo etc 5. Macules 6. Papules*Solid circumscribed elevation of the skin less than 0.5cm ... Large macule gt0.5cm diameter. Eg. Nevus flemmus (Hyper pigmentation) , vitiligo( hypo pigmented). ... Macules* A circumscribed change in skin color without elevation or depression of the skin i.e Non palpable. It is lt0.5cm ... E.g. Café au lait macules/spots, vitiligo, ... They include, macules, papules, pustules, patch etc *Secondary ...
15308847 - Comparison of characteristics of acquired bilateral nevus of ota-like macules and nevus.... 17955767 - Growth of ...
BACKGROUND: Acquired bilateral nevus of Ota-like macules (ABNOM), or Horis nevus, is a common dermal melanocytic ... Treatment of acquired bilateral nevus of Ota-like macules (Horis nevus) using 1064-nm ... ...
nevi. Also known as MOLES, are small dark skin growths that develop from melanocytes in the skin. ... macule. Is a discolored, flat spot that is less than 1cm in diameter. ...
Café-au-lait macules suggest neurofibromatosis, McCune-Albright syndrome and Watson syndrome. Epithelioid blue nevi may occur ... Another 40% may have darkly pigmented nodules admixed with the diffuse macules. In addition, some have café-au-lait macules. ... The epithelioid blue nevi are generally excised. While they are often suspected of being malignant, melanoma is an extremely ... "Epithelioid blue nevus and psammomatous melanotic schwannoma: the unusual pigmented skin tumors of the Carney complex". Semin ...
Macule- flat, circumscribed area of altered skin color, generally less than 1cm; examples- freckle, flat nevus ... Scabies- macules, papules, and linear erythematous lesions (classic burrow lesion is linear, curved, or S-shaped); intense ... Patch- macule that is greater than 1cm; examples- Mongolian or café au lait spots ... Impetigo- strep or staph infection; primary macule, papule or plaque becomes a secondary lesion with crust or scaling; lesion ...
  • Solitary cafe-au-lait macules are benign lesions that are common in the general population ( Figure 1 , Figure 2 ). (oncologynurseadvisor.com)
  • In patients with multiple cafe-au-lait spots it is important to obtain a family history of similar lesions or disorders known to be associated with cafe-au-lait macules. (oncologynurseadvisor.com)
  • The most common skin manifestation of TSC is hypomelanotic macules, previously termed ash leaf lesions. (clinicaladvisor.com)
  • Some reports propose that the skin lesions of BOS are elastic-type connective tissue nevi exclusively. (psychiatryadvisor.com)
  • Dermatopathology: The nodular lesions are often excised and almost invariably turn out to be heavily pigmented epithelioid blue nevi, although some are compound melanocytic nevi. (renalandurologynews.com)
  • We report a case of 21-year-old male with recurrent eczema lesions which were always localized within the underlying Becker's nevus lesion. (tripdatabase.com)
  • Lesions can appear at birth or in early infancy as light colored caf?au lait macules. (dermnet.com)
  • nevus comedo´nicus a rare epidermal nevus marked by one or more patches 2 to 5 cm or more in diameter, in which there are collections of large comedones or comedolike lesions. (thefreedictionary.com)
  • connective tissue nevus any nevus found in the dermal connective tissue with nodules, papules, plaques, or combinations of such lesions. (thefreedictionary.com)
  • These nevi are associated with other cutaneous and subcutaneous lesions, as well as neurofibromatosis and other developmental anomalies, and they exhibit a predisposition to development of malignant melanoma. (thefreedictionary.com)
  • In early lesions, typical site, age of onset and geographical outline help to differentiate Becker's nevus from nevoid and whorled hypermelanosis and from cafe-au-lait macule. (thefreedictionary.com)
  • Pigmented spindle cell nevus Spitz nevus Zosteriform lentiginous nevus Congenital melanocytic nevus These nevi are often categorized based on size, however, the lesions usually grow in proportion to the body over time, so the category may change over an individual's life. (wikipedia.org)
  • 6 mm, and evolution) are often used to distinguish nevi from melanomas in adults, while modified criteria (amelanosis, bleeding or bumps, uniform color, small diameter or de novo, and evolution) can be used when evaluating suspicious lesions in children. (wikipedia.org)
  • It was previously believed that there were autonomic alterations in nevus anemicus lesions, presumably increased stimulation of vasoconstrictor fibres or inhibition of vasodilator fibres of the blood vessels. (cfp.ca)
  • In contrast to nevus anemicus lesions, vitiligo lesions are well accentuated upon Wood light examination. (cfp.ca)
  • In addition, nevus depigmentosus lesions appear off-white upon Wood lamp examination. (cfp.ca)
  • The purpose of this study is to compare the efficacy and side effect profile of the QSRL and the frequency-doubled QSNd:YAG lasers in the removal of cutaneous pigmented lesions, including lentigines, cafe-au-lait macules, nevus of Ota, nevus spilus, Becker's nevus, postinflammatory hyperpigmentation, and melasma. (hairfacts.com)
  • Melanocytic lesions greater than 1 cm may be congenital nevi, atypical nevi, or melanoma. (mhmedical.com)
  • Recently, attention has been paid to nevi anemici (singular - nevus anemicus, NA) being a possible criterion as such lesions may be observed with increased frequency in NF1. (aad.org)
  • Several birthmark types are part of the group of skin lesions known as nevi or naevi, which means "birthmarks" in Latin. (wikipedia.org)
  • Although typically benign, a subset of Spitz lesions raise concern and create a diagnostic dilemma as a result of confusing histology that involves characteristics of classic Spitz nevi intermixed with features of cutaneous melanoma. (blogspot.com)
  • For example, the evaluation of the so called nevoid (spitzoid) melanoma, Spitz's nevi with conflicting criteria, or some benign simulators of malignant melanoma can pose seemingly insurmountable diagnostic problems. (springer.com)
  • Speckled lentiginous nevus is a benign neoplasm. (medscape.com)
  • Becker's Nevus (BN) is a benign hamartoma with an esthetically troublesome condition secondary to hyperpigmentation and hypertrichosis. (tripdatabase.com)
  • A Becker nevus is a common benign cutaneous melanocytic epidermal growth. (empr.com)
  • Neurofibromatosis Type 1 (NF1) is an autosomal dominant disorder on the long arm of chromosome 17, characterized by predominately benign tumor growth on nerve sheathes called neurofibromas and cutaneous spotting called café-au-lait macules. (physio-pedia.com)
  • The blue nevus is a benign, usually solitary lesion which is characterized by a localized proliferation of melanocytes and is believed to represent an abnormal arrest in embryonal migration of neural crest melanocytes [ 1 ]. (hindawi.com)
  • However, a benign subtype of genital nevi that occurs in young women is known as atypical melanocytic nevi. (omicsonline.org)
  • Halo nevus, also termed leukoderma acquisitum centrifugum or Sutton nevus, is a benign pigmented melanocytic nevus surrounded by a depigmented ring. (contemporarypediatrics.com)
  • Benign-appearing halo nevi warrant observation and periodic reexamination (eg, annually). (contemporarypediatrics.com)
  • Argon Laser Photoablation for Treating Benign Pigmented Conjunctival Nevi. (pubfacts.com)
  • To evaluate the outcomes of argon laser photoablation of benign conjunctival pigmented nevi with different clinical presentations. (pubfacts.com)
  • Patients presenting with benign conjunctival nevi were included. (pubfacts.com)
  • This photograph, made available by the National Cancer Institute (NCI), depicts a close view of a dermatology patient's skin surface, revealing a pigmented nevus spilus, a benign condition, which in this instance, had manifested as a cluster of flat brown macules, on a slightly hyperpigmented background. (cdc.gov)
  • Melanocytic nevi (moles) are common benign skin tumors. (mhmedical.com)
  • Most nevi are benign, but, atypical nevi have some features that resemble malignant melanoma, and in certain circumstances the presence of atypical nevi is a marker for an increased risk of developing malignant melanoma. (mhmedical.com)
  • Melanocytic nevi (moles) are among the most common benign tumors in humans. (mhmedical.com)
  • Nevi are benign hamartomas of melanocytic nevus cells. (mhmedical.com)
  • They represent a benign growth of nevus cells which are normally present in the skin. (drfechner.com)
  • Atypical (dysplastic) melanocytic nevus. (cengage.com)
  • Congenital melanocytic nevus. (cengage.com)
  • Frequently Asked Questions about Congenital Melanocytic Nevus (CMN) (Nevus Outreach, Inc. (medlineplus.gov)
  • Some authorities believe that speckled lentiginous nevus is a subtype of congenital melanocytic nevus. (medscape.com)
  • Torrelo A, de Prada I, Zambrano A, Happle R. Extensive speckled lentiginous nevus associated with giant congenital melanocytic nevus: an unusual example of twin spotting? (medscape.com)
  • It has been suggested that speckled lentiginous nevus is a subtype of congenital melanocytic nevus. (dermnet.com)
  • Acquired melanocytic nevus Types of acquired melanocytic nevi are categorized based on the location of cellsJunctional: epidermis Intradermal: dermis Compound: epidermis and dermis Atypical (dysplastic) nevus: This type of nevus must be diagnosed based on histological features. (wikipedia.org)
  • The diagnosis of Becker's nevus is typically made clinically, although a biopsy may be necessary in some cases to differentiate the lesion from congenital melanocytic nevus. (infectiousdiseaseadvisor.com)
  • To help differentiate it from congenital melanocytic nevus and smooth muscle hamartoma, it is important to ask whether the lesion was present at birth or developed subsequently. (infectiousdiseaseadvisor.com)
  • Thedifferential diagnosis includes congenital melanocytic nevus, congenitalsmooth muscle hamartoma, nevus spilus, and café au lait macules. (infectiousdiseaseadvisor.com)
  • Congenital melanocytic nevus is a type of melanocytic nevus, the medical term for what is colloquially called a "mole", found in infants at birth. (wikipedia.org)
  • The misreading of a section of a malignant melanoma as a nevus, which will then be left untreated, may result in regrowth at the biopsy site, may metastasize and lead to death. (springer.com)
  • At least 20 cases of cutaneous melanoma developing within a speckled lentiginous nevus have been reported. (medscape.com)
  • Based on Socik et al, perhaps a history of atypical nevi increases the risk of perianal melanoma. (aad.org)
  • She is actively involved in clinical research and she has published numerous papers on topics related to skin cancer with an emphasis on melanoma, atypical nevi, Spitz/Reed nevi and non-melanoma skin cancer. (whsmith.co.uk)
  • Nevus of Ota, also known as nevus fusculoceruleus ophthalmomaxillaris , is related to phacomatosis pigmentovascularis and melanoma . (malacards.org)
  • The strongest risk factors for the development of melanoma are the presence of numerous melanocytic nevi and the presence of atypical or dysplastic nevi. (pubmedcentralcanada.ca)
  • 7 The number and size of nevi are often used for determining the risk of developing melanoma. (pubmedcentralcanada.ca)
  • These nevi exhibit distinct morphological characteristics that sometimes overlap with those of cutaneous melanoma . (omicsonline.org)
  • thus, diagnosis relies significantly upon the experience and subjective judgment of pathologists to distinguish morphologically between atypical genital nevi and melanoma. (omicsonline.org)
  • The differential diagnosis for a halo nevus should include malignant melanoma, atypical nevus, and postinflammatory hypopigmentation. (contemporarypediatrics.com)
  • 1,3 Although the risk of melanoma developing in conjunction with halo nevi is rare, the presence of a nevus with changing color or border requires careful evaluation. (contemporarypediatrics.com)
  • A history of malignant melanoma in a first-degree relative or the presence of numerous melanotic nevi, which may be familial or sporadic, greatly increases the risk of developing malignant melanoma. (aafp.org)
  • Validity and reliability of dermoscopic criteria used to differentiate nevi from melanoma: a web-based international dermoscopy society study. (springer.com)
  • Oral melanoma can present as an unevenly shaped macule, plaque or mass, well circumscribed or diffused. (biomedcentral.com)
  • Swanson D.L. Swanson, David L. Nevi and Melanoma. (mhmedical.com)
  • Small blue macules ('maculae cerulae') or red papules - may be seen at feeding sites. (tripdatabase.com)
  • Light brown patch that develops an increasing number of pigmented macules or papules, representing junctional or compound nevi. (oncologynurseadvisor.com)
  • This patch contains a variable number of darkly pigmented macules and papules. (medscape.com)
  • They may present as lightly colored café au lait macules at birth, which later develop background hyperpigmentation and darkly pigmented macules and papules over months, years, or sometimes decades. (medscape.com)
  • Pigmented macules and papules then develop over a period of months to years. (dermnet.com)
  • Agminated blue nevi are dermal melanocytic proliferations that classically present as dark blue macules or papules in a grouped, linear, or blaschkoid distribution. (bioportfolio.com)
  • Nevus anelasticus characteristically is noted as small perifollicular papules on upper trunk in adolescence. (clinicaladvisor.com)
  • Hunter syndrome may be associated with a nevus mucinosis presenting as small firm papules (pebble-like) on arms, chest, scapular areas (X-linked recessive). (clinicaladvisor.com)
  • Congenital melanocytic nevi present at birth as solitary, discrete dark brown papules or plaques ( Figure 2 and Figure 3 ). (endocrinologyadvisor.com)
  • We diagnosed lesion on the right cheek area as Ota's nevus and those on both forehead and both lower eyelids as ABNOM by clinical and histologic findings. (bvsalud.org)
  • The malformed blood vessels appear as a spot or lesion called a nevus . (nih.gov)
  • Becker's Nevus with Recurrent Eczema Limited to the Nevus Lesion Several dermatoses have been reported in association with Becker's nevus . (tripdatabase.com)
  • blue nevus a dark blue nodular lesion composed of closely grouped melanocytes and melanophages in the mid-dermis. (thefreedictionary.com)
  • nevus of Ito a mongolian spot-like lesion having the same features as nevus of Ota except for localization to the areas of distribution of the posterior supraclavicular and lateral cutaneous brachial nerves, involving the shoulder, side of the neck, supraclavicular areas, and upper arm. (thefreedictionary.com)
  • Nevus is a nonspecific medical term for a visible, circumscribed, chronic lesion of the skin or mucosa. (wikipedia.org)
  • Hori's nevus Nevus spilus (speckled lentiginous nevus): This lesion includes dark speckles within a tan-brown background. (wikipedia.org)
  • 4 This theory is further supported by the donor dominance demonstrated after transplantation of a nevus anemicus lesion to normal skin (ie, pale appearance is retained). (cfp.ca)
  • Histopathologic findings for the nevus anemicus lesion are essentially the same as those for normal skin. (cfp.ca)
  • Reactive erythema will appear in the normal skin but not within the nevus anemicus lesion. (cfp.ca)
  • Becker's nevus is a cutaneous hamartoma composed of hair follicles and arrector pili muscles and is not a true nevomelanocytic lesion. (infectiousdiseaseadvisor.com)
  • Acquired bilateral nevus of Ota -like macules (ABNOM) are a common form of hyperpigmentation in Asian populations , characterized by brownish-blue or slate-gray pigmentation in the bilateral malar regions. (bvsalud.org)
  • A typical cafe-au-lait macule (homogeneous hyperpigmentation with smooth borders) in a teenager with NF1. (oncologynurseadvisor.com)
  • Hyperpigmentation overlying an early plexiform neurofibroma and typical cafe-au-lait macules in a child with NF1. (oncologynurseadvisor.com)
  • NF1-associated macules have recently been shown to be caused by a loss of both NF1 alleles in cultured melanocytes, although what role this plays in the hyperpigmentation is unclear. (oncologynurseadvisor.com)
  • Speckled lentiginous nevus is a patch of hyperpigmentation that can be seen on any area of the body. (medscape.com)
  • The background hyperpigmentation histologically has the features of a lentigo or caf?au lait macule. (dermnet.com)
  • Becker's nevus demonstrates fusion and flattening of the rete bases, mild hyperkeratosis, basalar hyperpigmentation and a few characteristic "rectangular" rete ridges. (infectiousdiseaseadvisor.com)
  • Biopsies are suggested to be into subcutaneous tissue and include adjacent normal skin to compare with the suspected connective tissue nevus. (clinicaladvisor.com)
  • Ota's nevus is mongolian spot -like macular blue-black or gray-brown patchy pigmentation that most commonly ocurrs in areas innervated by the first and second division of the trigeminal nerve . (bvsalud.org)
  • Hypo- and hypermelanotic cutaneous macules-retarded growth- intellectual disability syndrome is a rare, genetic pigmentation anomaly of the skin disorder characterized by congenital hypomelanotic and hypermelanotic cutaneous macules associated with, in some patients, retarded growth and intellectual disability. (nih.gov)
  • The term nevus is applied to a number of conditions caused by neoplasias and hyperplasias of melanocytes, as well as a number of pigmentation disorders, both hypermelanotic (containing increased melanin, the pigment responsible for skin color) and hypomelanotic (containing decreased melanin). (wikipedia.org)
  • Clinically, atypical nevi are characterized by variable pigmentation and irregular borders. (wikipedia.org)
  • Stage 2 occurs when the nevus loses its pigmentation, leaving a skin-colored macule or papule surrounded by depigmentation. (contemporarypediatrics.com)
  • The old acronyms of NAME (nevi, atrial myxoma, myxoid neurofibromas, ephelides [freckles]) and LAMB (lentigines, atrial myxoma, mucocutaneous myxomas, blue nevi) help one remember the major features. (renalandurologynews.com)
  • The spots range from 1 to 3 mm in diameter and may be lentigines, junctional, compound, or intraepidermal nevi. (dermnet.com)
  • Melasma, freckles, and lentigines are the epidermal disorders commonly seen, whilst nevus of Ota and acquired bilateral nevus of Ota-like macules are common dermal pigmentary disorders. (blogspot.com)
  • The common blue nevus is a flat to slightly elevated, smooth surfaced macule, papule, or plaque that is gray-blue to bluish black in color. (hindawi.com)
  • In stage 3, the papule or macule in the center vanishes completely, with only an oval or round patch of depigmentation remaining. (contemporarypediatrics.com)
  • 95% CI, 1.1-3.3).The authors concluded that perianal melanocytic nevi were common and were associated with prominent and atypical nevi elsewhere. (aad.org)
  • Dysplastic nevi are usually compound nevi with peripheral lentiginous and junctional activity and random cytological atypia in the epidermal component. (histopathology-india.net)
  • Compound nevi have both junctional and dermal components and are usually papular. (mhmedical.com)
  • Junctional nevi. (mhmedical.com)
  • Tinea versicolor is a common superficial fungal infection characterized by scaly hypopigmented or hyperpigmented macules or patches that most commonly appear on the chest, back, and proximal extremities. (cfp.ca)
  • Speckled lentiginous nevus may represent a localized defect in neural crest melanoblasts that populate a particular area of the skin. (medscape.com)
  • Mosaicism may be an explanation for the development of zosteriform speckled lentiginous nevus. (medscape.com)
  • Speckled lentiginous nevus can be associated with different disorders. (medscape.com)
  • Speckled lentiginous nevus has been studied in Canadian children of Asian and white European origins, and its prevalence is the same in both ethnic groups. (medscape.com)
  • The prevalence rate of speckled lentiginous nevus is 1.3-2.1% in school-aged children and adolescents. (medscape.com)
  • In rare instances of malignant transformation within a speckled lentiginous nevus, morbidity and mortality are dependent on the stage of the secondary malignancy. (medscape.com)
  • Regular visits to a dermatologist and careful examination with the use of photography should be used for early recognition of atypical features within a speckled lentiginous nevus. (medscape.com)
  • Speckled lentiginous nevus: within the spectrum of congenital melanocytic nevi. (medscape.com)
  • Altman DA, Banse L. Zosteriform speckled lentiginous nevus. (medscape.com)
  • Liu X, Zhao Z, Xu Q, Cai L, Zhang J. Speckled lentiginous nevus syndrome associated with an abnormality of tongue. (medscape.com)
  • Mendiratta V, Jabeen M, Barara M, Varshney M. Speckled lentiginous nevus syndrome with median nerve paresis: A rare syndrome with a new association. (medscape.com)
  • Speckled lentiginous nevus is flat and necessitates excision and closure if the patient desires removal. (dermnet.com)
  • In the final stage, repigmentation of the area occurs, resulting in the disappearance of the halo nevus completely. (contemporarypediatrics.com)
  • Each individual halo nevus may go through all 4 stages or may cease development at any stage. (contemporarypediatrics.com)
  • 2. Patrizi A, Bentivogli M, Raone B, Dondi A, Tabanelli M, Neri I . Association of halo nevus/i and vitiligo in childhood: a retrospective observational study. (contemporarypediatrics.com)
  • Some Becker's Nevus Melanocytes Remain Alive after Treatment with Q-Switched Alexandrite Laser 28566917 2018 11 13 1013-9087 29 3 2017 Jun Annals of dermatology Ann Dermatol Some Becker's Nevus Melanocytes Remain Alive after Treatment with Q-Switched Alexandrite Laser. (tripdatabase.com)
  • These are often congenital anomalies that include a variety of blue nevi such as the Nevus of Ota and Mongolian Spots. (wiley.com)
  • A Mongolian spot is a blue to slate gray, ill-defined macule or patch, most commonly noted on the back, sacrum, or buttocks. (endocrinologyadvisor.com)
  • Note the presence of hyperpigmented nevi (formerly called Mongolian spots), which arrive as despondent or gray, variably and irregularly shaped macules. (kramskoy.info)
  • Becker's nevus (BN) presents as a hairy patch or plaque with or without proliferation of the dermal smooth muscles. (tripdatabase.com)
  • 2,4 Skin biopsy shows a mononuclear infiltrate comprised primarily of macrophages, cytotoxic T cells, and Langerhans cells surrounding the nevus at the epidermal-dermal junction and within the papillary dermis. (contemporarypediatrics.com)
  • Vasospastic macules are a skin condition due to localized vasoconstriction and are seen most often in young women. (wikipedia.org)
  • In facial features, anorexia, cachexia, and eye and skin anomalies (FACES) syndrome, cutaneous findings include zosteriform speckled lentiginous nevi. (medscape.com)
  • Blue rubber bleb nevus syndrome is a condition in which the blood vessels do not develop properly in an area of the skin or other body organ (particularly the intestines). (nih.gov)
  • In general, blue rubber bleb nevus syndrome is characterized by skin spots (nevi) that may be few to hundreds in number. (nih.gov)
  • 3 Rates of malignancy are no different in Becker nevi compared with normal skin. (empr.com)
  • Skin Fold Freckling: Skin fold freckling are little brown macules that appear in regions where freckling is uncommon. (physio-pedia.com)
  • Blue nevi are most commonly found on the skin. (hindawi.com)
  • Skin examinations in 3 consecutive years (2004, 2005, and 2006) included full-body counts of nevi, skin color and tanning measurement using colorimetry, and hair and eye color evaluation by comparison with charts. (pubmedcentralcanada.ca)
  • The relationship between tanning and number of nevi was independent of the child's hair and eye color, parent-reported sun exposure, and skin phototype. (pubmedcentralcanada.ca)
  • Nevus anemicus becomes indistinguishable from the surrounding skin with diascopy. (cfp.ca)
  • 9 Nevus depigmentosus can be differentiated from nevus anemicus during physical examination: erythema occurs after stroking the skin in nevus depigmentosus but not in nevus anemicus. (cfp.ca)
  • Vitiligo is an acquired pigmentary disorder of the skin and mucous membranes that is characterized by circumscribed, depigmented macules and patches. (hindawi.com)
  • Another condition unique to Asian skin is acquired bilateral nevus of Ota-like macules (ABNOM). (dermatologytimes.com)
  • Congenitalmelanocytic nevi are present at birth and are typically darker incolor, raised, have no anatomic predilection and demonstrate melanocyticnevus cells on skin biopsy. (infectiousdiseaseadvisor.com)
  • Interestingly, nevi are also less common in patients with the melanocortin-1 receptor (MC1-R) gene pigment variant (red hair, fair skin, always burns). (mhmedical.com)
  • Nevi may occur anywhere but there is a predilection to sun-exposed skin. (mhmedical.com)
  • Intradermal nevi present with nevus cells confined to the dermis of the skin and are papular ( Figure 18-2 ). (mhmedical.com)
  • Bilateral nevus of Ota-like macule, a disease causing pigmented moles on the skin due to the existence of melanin cells that produce pigment in the thick skin, is a kind of spot. (miraelaserclinic.com)
  • Depending on the location of these nevus cells within the various layers of the skin, nevi can be flat (macule) or raised (nodule). (drfechner.com)
  • Another 40% may have darkly pigmented nodules admixed with the diffuse macules. (renalandurologynews.com)
  • Juvenile elastoma/nevus elasticus presents as multiple nodules on lower trunk and anterior thighs. (clinicaladvisor.com)
  • Acquired, bilateral nevus of Ota -like macules (ABNOM) is located bilaterally on the face , appears later in life , is blue-brown or slate-gray in color . (bvsalud.org)
  • 2006). Treatment of acquired bilateral nevus of ota-like macules (Hori's Nevus) with combination 532nm Q-switched Nd:YAG laser followed by 1064nm Q-switched Nd:YAG is more effective: Prospective Study. (cynosure.com)
  • The central nevus should be examined closely, and a biopsy performed if warranted. (contemporarypediatrics.com)
  • The biopsy report was checked and it was learned that this was an atypical Spitz nevus. (blogspot.com)
  • Laboratory studies and imaging are not necessary unless an associated genetic syndrome is suspected based on the presence of multiple cafe-au-lait macules, family history, or associated findings on history or physical examination. (oncologynurseadvisor.com)
  • Occasional findings include lipomas, epidermal nevi, and café au lait macules. (oncologynurseadvisor.com)
  • 1 This asymptomatic condition is characterized by a circumscribed pale-coloured macule or patch that can be of various size and shape (eg, rounded, oval, linear, or irregularly shaped) and that is sometimes surrounded by satellite macules. (cfp.ca)
  • Colloquially called a "stork bite", "angel's kiss" or "salmon patch", telangiectatic nevus appears as a pink or tanned, flat, irregularly shaped mark on the knee, back of the neck, and/or the forehead, eyelids and, sometimes, the top lip. (wikipedia.org)
  • An ash leaf macule is a well-demarcated hypopigmented macule or patch ( Figure 6 ). (endocrinologyadvisor.com)
  • Nevus depigmentosus manifests as a congenital, nonprogressive, hypopigmented macule or patch that remains stable throughout the patient's life. (cfp.ca)
  • Giant melanosomes and an increased number of melanocytes have been reported in NF1-associated cafe-au-lait macules, but are not specific for NF1. (oncologynurseadvisor.com)
  • Although the causes of both vitiligo and halo nevi are poorly understood, both are most commonly believed to be an immune-mediated process resulting from damage or destruction of melanocytes. (contemporarypediatrics.com)
  • A café au lait macule is characterized by a discrete, well-demarcated light brown (or "coffee with cream" colored) macule or patch ( Figure 1 ). (endocrinologyadvisor.com)
  • Nevus depigmentosa is likely a variant of an ash leaf macule and presents as a larger solitary hypopigmented patch ( Figure 7 ). (endocrinologyadvisor.com)
  • Becker's nevus usually presents as a unilateral, hyperpigmented, hypertrichotic patch ( Figure 1 ), with onset in early adulthood, usually during or shortly after puberty. (infectiousdiseaseadvisor.com)
  • Becker's nevus presenting as a hyperpigmented and markedly hypertrichotic patch. (infectiousdiseaseadvisor.com)
  • Certain vascular anomalies, such as salmon patch (nevus simplex) or infantile hemangioma, are very common. (aappublications.org)
  • Freckles, flat moles, and tattoos are examples of macules. (cueflash.com)
  • Spitz nevi represent a distinct type of melanocytic nevi more commonly seen in childhood. (blogspot.com)
  • compound nevus a nevocytic nevus composed of fully formed nests of nevus cells in the epidermis and newly forming ones in the dermis. (thefreedictionary.com)
  • intradermal nevus a type of nevocytic nevus clinically indistinguishable from compound nevus, in which the nests of nevus cells lie exclusively within the dermis. (thefreedictionary.com)
  • Host lymphocytic response around the vessels in the papillary dermis is prerequisite for the diagnosis of dysplastic nevus. (histopathology-india.net)
  • Multiple cafe-au-lait macules with irregular borders in a child who tested negative for NF1 and SPRED1 and no known underlying genetic syndrome. (oncologynurseadvisor.com)
  • The nevi displayed melanocytic proliferation, forming irregular and coalescent nests with a loss of cellular cohesion at several sites in the rete ridges. (omicsonline.org)
  • This disease can manifest with vascular malformations, segmental overgrowth, and epidermal nevi due to loss of heterozygosity in the affected tissues, a presentation known as SOLAMEN (segmental overgrowth with lipomatosis, arteriovenous malformation, and epidermal nevi). (oncologynurseadvisor.com)
  • Differential diagnoses include congenital melanocytic nevi, smooth muscle hamartomas, and café au lait macules. (empr.com)
  • Yarak S, Michalany NS, Heinke T, Stavale JN (2012) Clinical and Histopathological Characteristics of Genital Melanocytic Nevi: A Report of 109 Cases and a Review of the Literature. (omicsonline.org)
  • in addition, they display high clinical and histopathological variability and are mostly classified as common nevi. (omicsonline.org)
  • Halo nevi have 4 clinical stages of development. (contemporarypediatrics.com)
  • With respect to clinical features, nevus depigmentosus is very similar to nevus anemicus. (cfp.ca)
  • Which one of these clinical features would be most helpful in distinguishing hematoma from nevus? (dentalcare.com)
  • Nevus anemicus List of cutaneous conditions Rapini, Ronald P. (wikipedia.org)
  • 3 However, results of a sympathetic block study in nevus anemicus have since suggested that the primary defect could be due in part to increased local sensitivity to catecholamines. (cfp.ca)
  • Ultraviolet light, such as that produced by a Wood lamp, does not accentuate nevus anemicus. (cfp.ca)
  • Vitiligo is the most important differential diagnosis-nevus anemicus is often misdiagnosed as vitiligo, leading to inappropriate overtreatment. (cfp.ca)
  • The hypopigmented patches, although accompanied by minimal scaling, can simulate nevus anemicus, and need to be confirmed by a potassium hydroxide wet-mount preparation showing the presence of yeast (classic cases are described as having a "spaghetti and meatballs" appearance). (cfp.ca)
  • 2. Vaassen P, Rosenbaum T. Nevus anemicus as an additional diagnostic marker of neurofibromatosis type I in childhood. (aad.org)
  • Patients have multiple pigmented macules ( Figure 1 , Figure 2 ), most commonly on the face and trunk. (renalandurologynews.com)
  • such nevi vary widely in appearance, size, and distribution and are commonly hyperkeratotic. (thefreedictionary.com)
  • Nevus sebaceus is a yellowish pink, well-demarcated, slightly raised oval plaque, most commonly seen on the scalp ( Figure 9 and Figure 10 ). (endocrinologyadvisor.com)
  • The nevus itself is most commonly acquired, but rarely develops around congenital nevi. (contemporarypediatrics.com)
  • The term nevus is included in the names of multiple dermatologic syndromes: Basal cell nevus syndrome Blue rubber bleb nevus syndrome Dysplastic nevus syndrome Epidermal nevus syndrome Linear nevus sebaceous syndrome A nevus may also be spelled naevus. (wikipedia.org)
  • Isolated segmental cafe-au-lait macule in a young child. (oncologynurseadvisor.com)
  • Cafe-au-lait macules may be present at birth or appear within the first few years of life. (oncologynurseadvisor.com)
  • Cafe-au-lait macules can appear anywhere on the body, but are most common on the trunk and extremities and least common on the face. (oncologynurseadvisor.com)
  • Cafe-au-lait macules are usually randomly distributed, but when limited to a single body region should raise the suspicion for segmental NF1 ( Figure 4 ). (oncologynurseadvisor.com)
  • Multiple cafe-au-lait macules and inguinal freckling in a child with segmental NF1. (oncologynurseadvisor.com)
  • Often smaller and darker than cafe-au-lait macules, with distinct histology. (oncologynurseadvisor.com)
  • The prevalence of a solitary cafe-au-lait macule is estimated to be 3-36%, depending on the population studied. (oncologynurseadvisor.com)
  • Cafe-au-lait macules are more common in African Americans than in Caucasians. (oncologynurseadvisor.com)
  • The etiology of sporadic cafe-au-lait macules is unknown. (oncologynurseadvisor.com)
  • Cafe au lait macules, Beckers nevi and some other tan/brown birthmarks may be treated using a Q-switched laser. (umich.edu)
  • Cafe-au-lait macules (CALM): CALM is one of the most prevalent features of NF1. (physio-pedia.com)
  • Clinically it presents as a light brown macule with a geographic pattern and sharply demarcated borders. (empr.com)
  • Intense pulsed light treatment for Becker's nevus. (tripdatabase.com)
  • Eczematous dermatitis associated with Becker's nevus is extremely rare, described in only two previous case reports. (tripdatabase.com)
  • Clinicopathologic characteristics of early-onset Becker's nevus in Korean children and adolescents. (tripdatabase.com)
  • 2. Person JR, Longcope C. Becker's nevus: an androgen-mediated hyperplasia with increased androgen receptors . (empr.com)
  • 3. Lapidoth M, Adatto M, Ben-Amitai D, Cohen S, Halachmi S. Hypertrichosis in Becker's nevus: effective low-fluence laser hair removal . (empr.com)
  • Becker's nevus Blue nevus (rarely congenital): A classic blue nevus is usually smaller than 1 cm, flat, and blue-black in color. (wikipedia.org)
  • Hence the term, Becker's nevus, is actually a misnomer. (infectiousdiseaseadvisor.com)
  • Becker's nevus with mild breast hypoplasia without hair. (infectiousdiseaseadvisor.com)
  • Increased number of arrector pilimuscles may be seen and represents the smooth muscle hamartomatouscomponent of the Becker's nevus ( Figure 5 ). (infectiousdiseaseadvisor.com)
  • Becker's nevus with associated smooth muscle proliferation. (infectiousdiseaseadvisor.com)
  • called also leukoderma acquisitum centrifugum , Sutton's disease , and Sutton's nevus . (thefreedictionary.com)
  • The authors describe the first case of eye amelanotic cellular blue nevus reported in literature and discuss the main differential diagnosis. (hindawi.com)
  • Another clue to the diagnosis of NF1 includes juvenile xanthogranulomas in the context of a child with café au lait macules. (aad.org)
  • Angiospastic macules (Bier spots). (cengage.com)
  • Symptoms of Ota-like macule - Brown or blue spots appear around the eyes, the temple, forehead and nose. (miraelaserclinic.com)
  • Common terms, including mole, birthmark, and beauty mark, are used to describe nevi, but these terms do not distinguish specific types of nevi from one another. (wikipedia.org)
  • Dysplastic (atypical) nevus syndrome includes familial (originally known as B-K mole syndrome) and sporadic occurrence of multiple dysplastic nevi in an individual. (histopathology-india.net)
  • It appears as painless, blue/gray/black, nonulcerated, soft macule without any erythematous reaction surrounding it. (wikipedia.org)
  • Dry, scaly erythematous macules and patches. (icls.ca)
  • The brown area is usually flat, and the black dots may be slightly elevated and contain typical nevus cells. (dermnet.com)

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