Macaca mulatta: A species of the genus MACACA inhabiting India, China, and other parts of Asia. The species is used extensively in biomedical research and adapts very well to living with humans.Adolescent Development: The continuous sequential physiological and psychological changes during ADOLESCENCE, approximately between the age of 13 and 18.Monkey Diseases: Diseases of Old World and New World monkeys. This term includes diseases of baboons but not of chimpanzees or gorillas (= APE DISEASES).Macaca: A genus of the subfamily CERCOPITHECINAE, family CERCOPITHECIDAE, consisting of 16 species inhabiting forests of Africa, Asia, and the islands of Borneo, Philippines, and Celebes.Thailand: Formerly known as Siam, this is a Southeast Asian nation at the center of the Indochina peninsula. Bangkok is the capital city.PrimatesMacaca fascicularis: A species of the genus MACACA which typically lives near the coast in tidal creeks and mangrove swamps primarily on the islands of the Malay peninsula.ChileHaplorhini: A suborder of PRIMATES consisting of six families: CEBIDAE (some New World monkeys), ATELIDAE (some New World monkeys), CERCOPITHECIDAE (Old World monkeys), HYLOBATIDAE (gibbons and siamangs), CALLITRICHINAE (marmosets and tamarins), and HOMINIDAE (humans and great apes).Trees: Woody, usually tall, perennial higher plants (Angiosperms, Gymnosperms, and some Pterophyta) having usually a main stem and numerous branches.Influenza A virus: The type species of the genus INFLUENZAVIRUS A that causes influenza and other diseases in humans and animals. Antigenic variation occurs frequently between strains, allowing classification into subtypes and variants. Transmission is usually by aerosol (human and most non-aquatic hosts) or waterborne (ducks). Infected birds shed the virus in their saliva, nasal secretions, and feces.Influenza, Human: An acute viral infection in humans involving the respiratory tract. It is marked by inflammation of the NASAL MUCOSA; the PHARYNX; and conjunctiva, and by headache and severe, often generalized, myalgia.Influenza A Virus, H1N1 Subtype: A subtype of INFLUENZA A VIRUS with the surface proteins hemagglutinin 1 and neuraminidase 1. The H1N1 subtype was responsible for the Spanish flu pandemic of 1918.Influenza in Birds: Infection of domestic and wild fowl and other BIRDS with INFLUENZA A VIRUS. Avian influenza usually does not sicken birds, but can be highly pathogenic and fatal in domestic POULTRY.Influenza Vaccines: Vaccines used to prevent infection by viruses in the family ORTHOMYXOVIRIDAE. It includes both killed and attenuated vaccines. The composition of the vaccines is changed each year in response to antigenic shifts and changes in prevalence of influenza virus strains. The vaccine is usually bivalent or trivalent, containing one or two INFLUENZAVIRUS A strains and one INFLUENZAVIRUS B strain.Influenza A Virus, H5N1 Subtype: A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 5 and neuraminidase 1. The H5N1 subtype, frequently referred to as the bird flu virus, is endemic in wild birds and very contagious among both domestic (POULTRY) and wild birds. It does not usually infect humans, but some cases have been reported.Influenza A Virus, H3N2 Subtype: A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 3 and neuraminidase 2. The H3N2 subtype was responsible for the Hong Kong flu pandemic of 1968.Interferons: Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions.Influenza B virus: Species of the genus INFLUENZAVIRUS B that cause HUMAN INFLUENZA and other diseases primarily in humans. Antigenic variation is less extensive than in type A viruses (INFLUENZA A VIRUS) and consequently there is no basis for distinct subtypes or variants. Epidemics are less likely than with INFLUENZA A VIRUS and there have been no pandemics. Previously only found in humans, Influenza B virus has been isolated from seals which may constitute the animal reservoir from which humans are exposed.Social Behavior: Any behavior caused by or affecting another individual, usually of the same species.Taxus: Genus of coniferous yew trees or shrubs, several species of which have medicinal uses. Notable is the Pacific yew, Taxus brevifolia, which is used to make the anti-neoplastic drug taxol (PACLITAXEL).Paternity: Establishing the father relationship of a man and a child.Injections, Epidural: The injection of drugs, most often analgesics, into the spinal canal without puncturing the dura mater.Simian immunodeficiency virus: Species of the genus LENTIVIRUS, subgenus primate immunodeficiency viruses (IMMUNODEFICIENCY VIRUSES, PRIMATE), that induces acquired immunodeficiency syndrome in monkeys and apes (SAIDS). The genetic organization of SIV is virtually identical to HIV.Behavior, Animal: The observable response an animal makes to any situation.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Histocompatibility Antigens Class I: Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits of class I antigens and play an important role in determining the serological specificity of the surface antigen. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells.Genes, MHC Class I: Genetic loci in the vertebrate major histocompatibility complex which encode polymorphic characteristics not related to immune responsiveness or complement activity, e.g., B loci (chicken), DLA (dog), GPLA (guinea pig), H-2 (mouse), RT-1 (rat), HLA-A, -B, and -C class I genes of man.Macaca nemestrina: A species of the genus MACACA which inhabits Malaya, Sumatra, and Borneo. It is one of the most arboreal species of Macaca. The tail is short and untwisted.Amyloid beta-Peptides: Peptides generated from AMYLOID BETA-PEPTIDES PRECURSOR. An amyloid fibrillar form of these peptides is the major component of amyloid plaques found in individuals with Alzheimer's disease and in aged individuals with trisomy 21 (DOWN SYNDROME). The peptide is found predominantly in the nervous system, but there have been reports of its presence in non-neural tissue.Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)SwitzerlandPeptide Fragments: Partial proteins formed by partial hydrolysis of complete proteins or generated through PROTEIN ENGINEERING techniques.Amyloid: A fibrous protein complex that consists of proteins folded into a specific cross beta-pleated sheet structure. This fibrillar structure has been found as an alternative folding pattern for a variety of functional proteins. Deposits of amyloid in the form of AMYLOID PLAQUES are associated with a variety of degenerative diseases. The amyloid structure has also been found in a number of functional proteins that are unrelated to disease.Vaccination: Administration of vaccines to stimulate the host's immune response. This includes any preparation intended for active immunological prophylaxis.Amyloid beta-Protein Precursor: A single-pass type I membrane protein. It is cleaved by AMYLOID PRECURSOR PROTEIN SECRETASES to produce peptides of varying amino acid lengths. A 39-42 amino acid peptide, AMYLOID BETA-PEPTIDES is a principal component of the extracellular amyloid in SENILE PLAQUES.Plaque, Amyloid: Accumulations of extracellularly deposited AMYLOID FIBRILS within tissues.

Cerebellar Purkinje cell simple spike discharge encodes movement velocity in primates during visuomotor arm tracking. (1/10531)

Pathophysiological, lesion, and electrophysiological studies suggest that the cerebellar cortex is important for controlling the direction and speed of movement. The relationship of cerebellar Purkinje cell discharge to the control of arm movement parameters, however, remains unclear. The goal of this study was to examine how movement direction and speed and their interaction-velocity-modulate Purkinje cell simple spike discharge in an arm movement task in which direction and speed were independently controlled. The simple spike discharge of 154 Purkinje cells was recorded in two monkeys during the performance of two visuomotor tasks that required the animals to track targets that moved in one of eight directions and at one of four speeds. Single-parameter regression analyses revealed that a large proportion of cells had discharge modulation related to movement direction and speed. Most cells with significant directional tuning, however, were modulated at one speed, and most cells with speed-related discharge were modulated along one direction; this suggested that the patterns of simple spike discharge were not adequately described by single-parameter models. Therefore, a regression surface was fitted to the data, which showed that the discharge could be tuned to specific direction-speed combinations (preferred velocities). The overall variability in simple spike discharge was well described by the surface model, and the velocities corresponding to maximal and minimal discharge rates were distributed uniformly throughout the workspace. Simple spike discharge therefore appears to integrate information about both the direction and speed of arm movements, thereby encoding movement velocity.  (+info)

Onset of nucleolar and extranucleolar transcription and expression of fibrillarin in macaque embryos developing in vitro. (2/10531)

Specific aims were to characterize the onset of nucleolar and extranucleolar transcription and expression of the nucleolar protein fibrillarin during preimplantation development in vitro in macaque embryos using autoradiographic and immunocytochemical techniques. Autoradiography was performed on whole embryos cultured with [3H]uridine for assessment of nucleolar (rRNA) and extranucleolar (mRNA) transcription. Expression of fibrillarin was immunocytochemically assessed in whole embryos using a primary antibody against fibrillarin and a fluorescein isothiocyanate-conjugated secondary antibody. Extranucleolar incorporation of [3H]uridine was first detected in 2-cell embryos cultured 6-10 h with [3H]uridine. Culture with alpha-amanitin prevented incorporation of label in 2-cell embryos, and treatment with ribonuclease reduced the signal to background levels, indicating that [3H]uridine was incorporated into mRNA and not rRNA or DNA. Nucleolar incorporation of [3H]uridine was not evident in pronucleate-stage or 2- to 5-cell embryos, but it was detected in one 6-cell embryo and in all 8-cell to blastocyst-stage embryos. Fibrillarin was first expressed in some 6- to 7-cell embryos, but it was consistently expressed in all 8-cell embryos. Fibrillarin was localized to the perimeter of the nucleolar precursor bodies, forming a ring that completely encapsulated these structures. Fibrillarin was not expressed in 8- to 16-cell embryos cultured with alpha-amanitin, indicating that it is transcribed, rather than recruited, at the 8-cell stage. In conclusion, in in vitro-fertilized macaque embryos developing in vitro, extranucleolar synthesis of mRNA is initiated at the 2-cell stage while the onset of nucleolar transcription occurs at the 6- to 8-cell stage, coincident with expression of fibrillarin.  (+info)

Association of simian virus 40 with a central nervous system lesion distinct from progressive multifocal leukoencephalopathy in macaques with AIDS. (3/10531)

The primate polyomavirus SV40 is known to cause interstitial nephritis in primary infections and progressive multifocal leukoencephalopathy (PML) upon reactivation of a latent infection in SIV-infected macaques. We now describe a second central nervous system manifestation of SV40: a meningoencephalitis affecting cerebral gray matter, without demyelination, distinct from PML. Meningoencephalitis appears also to be a primary manifestation of SV40 infection and can be seen in conjunction with SV40-induced interstitial nephritis and pneumonitis. The difference in the lesions of meningoencephalitis and PML does not appear to be due to cellular tropism, as both oligodendrocytes and astrocytes are infected in PML and meningoencephalitis, as determined by in situ hybridization or immunohistochemistry for SV40 coupled with immunohistochemistry for cellular determinants. This is further supported by examination of SV40 nucleic acid sequences from the ori-enhancer and large-T-antigen regions, which reveals no tissue-or lesion-specific variation in SV40 sequences.  (+info)

Loss of D2 receptor binding with age in rhesus monkeys: importance of correction for differences in striatal size. (4/10531)

The relation between striatal dopamine D2 receptor binding and aging was investigated in rhesus monkeys with PET. Monkeys (n = 18, 39 to 360 months of age) were scanned with 11C-raclopride; binding potential in the striatum was estimated graphically. Because our magnetic resonance imaging analysis revealed a concomitant relation between size of striatum and age, the dynamic positron emission tomography (PET) data were corrected for possible partial volume (PV) artifacts before parameter estimation. The age-related decline in binding potential was 1% per year and was smaller than the apparent effect if the age-related change in size was ignored. This is the first in vivo demonstration of a decline in dopamine receptor binding in nonhuman primates. The rate of decline in binding potential is consistent with in vitro findings in monkeys but smaller than what has been measured previously in humans using PET. Previous PET studies in humans, however, have not corrected for PV error, although a decline in striatal size with age has been demonstrated. The results of this study suggest that PV correction must be applied to PET data to accurately detect small changes in receptor binding that may occur in parallel with structural changes in the brain.  (+info)

MST neuronal responses to heading direction during pursuit eye movements. (5/10531)

As you move through the environment, you see a radial pattern of visual motion with a focus of expansion (FOE) that indicates your heading direction. When self-movement is combined with smooth pursuit eye movements, the turning of the eye distorts the retinal image of the FOE but somehow you still can perceive heading. We studied neurons in the medial superior temporal area (MST) of monkey visual cortex, recording responses to FOE stimuli presented during fixation and smooth pursuit eye movements. Almost all neurons showed significant changes in their FOE selective responses during pursuit eye movements. However, the vector average of all the neuronal responses indicated the direction of the FOE during both fixation and pursuit. Furthermore, the amplitude of the net vector increased with increasing FOE eccentricity. We conclude that neuronal population encoding in MST might contribute to pursuit-tolerant heading perception.  (+info)

Eye movement deficits following ibotenic acid lesions of the nucleus prepositus hypoglossi in monkeys II. Pursuit, vestibular, and optokinetic responses. (6/10531)

The eyes are moved by a combination of neural commands that code eye velocity and eye position. The eye position signal is supposed to be derived from velocity-coded command signals by mathematical integration via a single oculomotor neural integrator. For horizontal eye movements, the neural integrator is thought to reside in the rostral nucleus prepositus hypoglossi (nph) and project directly to the abducens nuclei. In a previous study, permanent, serial ibotenic acid lesions of the nph in three rhesus macaques compromised the neural integrator for fixation but saccades were not affected. In the present study, to determine further whether the nph is the neural substrate for a single oculomotor neural integrator, the effects of those lesions on smooth pursuit, the vestibulo-ocular reflex (VOR), vestibular nystagmus (VN), and optokinetic nystagmus (OKN) are documented. The lesions were correlated with long-lasting deficits in eye movements, indicated most clearly by the animals' inability to maintain steady gaze in the dark. However, smooth pursuit and sinusoidal VOR in the dark, like the saccades in the previous study, were affected minimally. The gain of horizontal smooth pursuit (eye movement/target movement) decreased slightly (<25%) and phase lead increased slightly for all frequencies (0.3-1.0 Hz, +/-10 degrees target tracking), most noticeably for higher frequencies (0.8-0.7 and approximately 20 degrees for 1.0-Hz tracking). Vertical smooth pursuit was not affected significantly. Surprisingly, horizontal sinusoidal VOR gain and phase also were not affected significantly. Lesions had complex effects on both VN and OKN. The plateau of per- and postrotatory VN was shortened substantially ( approximately 50%), whereas the initial response and the time constant of decay decreased slightly. The initial OKN response also decreased slightly, and the charging phase was prolonged transiently then recovered to below normal levels like the VN time constant. Maximum steady-state, slow eye velocity of OKN decreased progressively by approximately 30% over the course of the lesions. These results support the previous conclusion that the oculomotor neural integrator is not a single neural entity and that the mathematical integrative function for different oculomotor subsystems is most likely distributed among a number of nuclei. They also show that the nph apparently is not involved in integrating smooth pursuit signals and that lesions of the nph can fractionate the VOR and nystagmic responses to adequate stimuli.  (+info)

Frontal cognitive impairments and saccadic deficits in low-dose MPTP-treated monkeys. (7/10531)

There is considerable overlap between the cognitive deficits observed in humans with frontal lobe damage and those described in patients with Parkinson's disease. Similar frontal impairments have been found in the 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine (MPTP) primate model of Parkinsonism. Here we provide quantitative documentation of the cognitive, oculomotor, and skeletomotor dysfunctions of monkeys trained on a frontal task and treated with low-doses (LD) of MPTP. Two rhesus monkeys were trained to perform a spatial delayed-response task with frequent alternations between two behavioral modes (GO and NO-GO). After control recordings, the monkeys were treated with one placebo and successive LD MPTP courses. Monkey C developed motor Parkinsonian signs after a fourth course of medium-dose (MD) MPTP and later was treated with combined dopaminergic therapy (CDoT). There were no gross motor changes after the LD MPTP courses, and the average movement time (MT) did not increase. However, reaction time (RT) increased significantly. Both RT and MT were further increased in the symptomatic state, under CDoT. Self-initiated saccades became hypometric after LD MPTP treatments and their frequency decreased. Visually triggered saccades were affected to a lesser extent by the LD MPTP treatments. All saccadic parameters declined further in the symptomatic state and improved partially during CDoT. The number of GO mode (no-response, location, and early release) errors increased after MPTP treatment. The monkeys made more perseverative errors while switching from the GO to the NO-GO mode. Saccadic eye movement patterns suggest that frontal deficits were involved in most observed errors. CDoT had a differential effect on the behavioral errors. It decreased omission errors but did not improve location errors or perseverative errors. Tyrosine hydroxylase immunohistochemistry showed moderate ( approximately 70-80%) reduction in the number of dopaminergic neurons in the substantia nigra pars compacta after MPTP treatment. These results show that cognitive and motor disorders can be dissociated in the LD MPTP model and that cognitive and oculomotor impairments develop before the onset of skeletal motor symptoms. The behavioral and saccadic deficits probably result from the marked reduction of dopaminergic neurons in the midbrain. We suggest that these behavioral changes result from modified neuronal activity in the frontal cortex.  (+info)

Visuomotor processing as reflected in the directional discharge of premotor and primary motor cortex neurons. (8/10531)

Premotor and primary motor cortical neuronal firing was studied in two monkeys during an instructed delay, pursuit tracking task. The task included a premovement "cue period," during which the target was presented at the periphery of the workspace and moved to the center of the workspace along one of eight directions at one of four constant speeds. The "track period" consisted of a visually guided, error-constrained arm movement during which the animal tracked the target as it moved from the central start box along a line to the opposite periphery of the workspace. Behaviorally, the animals tracked the required directions and speeds with highly constrained trajectories. The eye movements consisted of saccades to the target at the onset of the cue period, followed by smooth pursuit intermingled with saccades throughout the cue and track periods. Initially, an analysis of variance (ANOVA) was used to test for direction and period effects in the firing. Subsequently, a linear regression analysis was used to fit the average firing from the cue and track periods to a cosine model. Directional tuning as determined by a significant fit to the cosine model was a prominent feature of the discharge during both the cue and track periods. However, the directional tuning of the firing of a single cell was not always constant across the cue and track periods. Approximately one-half of the neurons had differences in their preferred directions (PDs) of >45 degrees between cue and track periods. The PD in the cue or track period was not dependent on the target speed. A second linear regression analysis based on calculation of the preferred direction in 20-ms bins (i.e., the PD trajectory) was used to examine on a finer time scale the temporal evolution of this change in directional tuning. The PD trajectories in the cue period were not straight but instead rotated over the workspace to align with the track period PD. Both clockwise and counterclockwise rotations occurred. The PD trajectories were relatively straight during most of the track period. The rotation and eventual convergence of the PD trajectories in the cue period to the preferred direction of the track period may reflect the transformation of visual information into motor commands. The widely dispersed PD trajectories in the cue period would allow targets to be detected over a wide spatial aperture. The convergence of the PD trajectories occurring at the cue-track transition may serve as a "Go" signal to move that was not explicitly supplied by the paradigm. Furthermore, the rotation and convergence of the PD trajectories may provide a mechanism for nonstandard mapping. Standard mapping refers to a sensorimotor transformation in which the stimulus is the object of the reach. Nonstandard mapping is the mapping of an arbitrary stimulus into an arbitrary movement. The shifts in the PD may allow relevant visual information from any direction to be transformed into an appropriate movement direction, providing a neural substrate for nonstandard stimulus-response mappings.  (+info)

*It's a Bit Complicated

Macaca Mulatta 0 5 years ago in MP3s (23 July 2006). "Macaca Mulatta". Another Form of Relief. Retrieved 2012-02-25. "Macaca ... "Macaca Mulatta , blog op Myspace". Myspace.com. Retrieved 2012-02-25. ChrisChinchilla Chris Chinchilla+ Add Contact (19 ... "Macaca Mulatta Album Recording , Flickr - Photo Sharing!". Flickr. Retrieved 2012-02-25. Phares, Heather (19 June 2007). " ... It's like pick-up sticks or legos or something'. After leaving the group, Chinchilla formed a new band, Macaca Mulata, with ...

*List of mammals of Florida

Eudey, A. & Members of the Primate Specialist Group (2000). "Macaca mulatta". IUCN Red List of Threatened Species. Version 2006 ...

*MirGeneDB

Eutheria (Placental mammals) • Human (Homo sapiens) • Rhesus monkey (Macaca mulatta) • House mouse (Mus musculus) • Norway rat ...

*Brodmann area

Gerhardt von Bonin & Percival Bailey (1925). The Neocortex of Macaca Mulatta (PDF). Urbana, Illinois: The University of ...

*Ethogram

Macaca mulatta) behavior". Applied Animal Behaviour Science. 122 (1): 53-57. doi:10.1016/j.applanim.2009.11.002. A sample ...

*FAM203B

Table of FAM203B Paralog and Homologs: There is one ortholog of FAM203B, brain protein 16-like (BRP16L) in Macaca mulatta, ... "Predicted: brain protein 16-like [Macaca mulatta]". NCBI Protein. Retrieved 5 February 2013. "Predicted: brain protein 16-like ... The large amount of time since the divergence of the M. mulatta and D. rerio lineages suggests that these BRP16L genes are the ... If the BRP16L genes in "M mulatta" and "D. rerio" are the result of separate duplication events, then it is also possible that ...

*Object permanence

Filion, C. M.; Washburn, D. A.; Gulledge, J. P. (1996). "Can monkeys (Macaca mulatta) represent invisible displacement?". J. ...

*List of mass spectrometry software

Tannu, Nilesh S; Hemby, Scott E (2007). "De novo protein sequence analysis of Macaca mulatta". BMC Genomics. 8: 270. doi: ...

*William Charles Osman Hill

ISBN 978-0-12-528750-0. Osman Hill, W. C. (1972). "Taxonomic status of the Macaques Macaca mulatta Zimm. and Macaca irus Cuvier ... Dittus, W., Watson, A. & Molur, S. (2008). "Macaca sinica ssp. opisthomelas". IUCN Red List of Threatened Species. Version ... Osman Hill, W. C. (1974). Primates Comparative Anatomy and Taxonomy VII-Cynopithecinae (Cercocebus, Macaca, Cynopithecus). ... Macaca sinica), the highland toque macaque (M. s. opisthomelas) in 1942; one subspecies of red slender loris (Loris tardigradus ...

*John E. Pickering

Kent, S. P., & Pickering, J. E. (1958). Neoplasms in monkeys (Macaca mulatta): spontaneous and irradiation induced. Cancer, 11( ... Macaca mulatta): spontaneous and irradiation induced The Effects of Barium140-Lanthanum146 (Gamma) Radiation on the Central ...

*Wildlife of Pakistan

CS1 maint: Uses authors parameter (link) Goldstein, S.J. and Richard, A.F. (1989). "Ecology of rhesus macaques (Macaca mulatta ...

*Batroxobin

The safe dose for rats is 3.0 KU/kg and for Macaca mulatta 1.5 KU/kg. The lethal dose has only been studied in mice and is ... In Macaca mulatta, the fibrinogen concentration was significantly decreased and the decrease was dose-dependent. There was a ... The long-term effects of batroxobin are tested on rats and Macaca mulatta. The subjects received an injection of batroxobin ... These animals include rats, mice, Macaca mulatta and rabbits. At low dose the batroxobin significantly shortened bleeding times ...

*PBDC1

S127 was left in the table even though Homo sapiens and Macaca mulatta did not have significant scores above threshold for that ... Through evolutionary change, the serine in Bombus was changed to a tyrosine in Homo sapiens and Macaca mulatta, which is still ... When comparing the predicted phosphorylation sites, those shown in the table below were those conserved in Macaca mulatta as ... Lysine 63 was conserved in both Macaca mulatta and Bombus impatiens. There are 10 serine, 3 threonine, and 6 tyrosine ...

*RTL6

"RTL6 retrotransposon Gag like 6 [Macaca mulatta (Rhesus monkey)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2017-05-06. " ...

*Cheating (biology)

Hauser, M.D. (1992). "Costs of deception: cheaters are punished in rhesus monkeys (Macaca mulatta)". Proceedings of the ...

*Social animal

"Population Patterns and Behavioral Ecology of Rhesus Monkeys (Macaca Mulatta) in Nepal." The Macaques: Studies in ecology, ...

*List of organisms by chromosome count

Macaca mulatta)". Age (Dordr). 29: 15-28. doi:10.1007/s11357-006-9016-6. PMC 2267682 . PMID 19424827. "Rnor_6.0 - Assembly - ...

*Cognitive genomics

Rhesus macaques (Macaca mulatta) exhibit a 93% genetic similarity to humans approximately. They are often used as an out-group ...

*Cathelicidin

Bals R, Lang C, Weiner DJ, Vogelmeier C, Welsch U, Wilson JM (March 2001). "Rhesus monkey (Macaca mulatta) mucosal ...

*Gecker

Macaca mulatta)". Journal of the Acoustical Society of America. 121: 575-585. Jacobus, Sharon; Loy, James (July 1981). "The ... Macaca mulatta) on Cayo Santiago". Behaviour. 140 (7): 899-924. Elowson, A. Margaret; Snowdon, Charles T.; Lazaro-Perea, ...

*Kedarnath Wildlife Sanctuary

The primates recorded are rhesus macaque (Macaca mulatta) and common langur (Presbytis entellus). Among the smaller mammals are ...

*Kosmos 1887

Two rhesus macaques (Macaca mulatta) named Drema and Yerosha occupied the Primate-BIOS. NSSDC ID 1987-083A Other Names ...

*NLRP5

Macaca mulatta)". Hum. Reprod. 24 (2): 415-24. doi:10.1093/humrep/den403. PMID 19054779. Pisani LF, Ramelli P, Lazzari B, ...

*Elizabeth M. Brannon

PMC 3864890 Drucker, C., & Brannon, E. M. (2014). "Rhesus monkeys (Macaca mulatta) map number onto space," Cognition, 132(1), ...

*Henkjan Honing

Honing, H.; Merchant, H.; Háden, G.P.; Prado, L.; Bartolo, R. (2012). "Rhesus monkeys (Macaca mulatta) detect rhythmic groups ...

*John R. Lukacs

Macaca mulatta). [American Journal of Physical Anthropology] 107: 179-186. Lukacs, J. R. and S. R. Walimbe (1998). ...
The impact of maternal kinship on social behaviour has been studied in detail for many primate species, but it is difficult to assess the importance of kin selection in shaping the evolution of social behaviour when studies are limited to maternal kin, completely ignoring paternal kinship. This thesis aimed to investigate the extent of paternal kinship and its impact on the social relationships among adult females in one group of free-ranging rhesus macaques (Macaca mulatta) living on the island of Cayo Santiago. The main findings can be summarised as follows: Firstly, in order to access the extent of paternal kinship, paternity has been analysed for all infants of the study group born between 1993 and 1998. Results revealed that male reproduction was highly skewed over the study period as few males have sired a high number of offspring, but the majority of potential sires have sired no or few offspring. This created a kinship structure in which nearly all animals born during the study period ...
Borries C, Larney E, Kreetiyutanont K, Koenig A. 2002. The diurnal primate community in a dry evergreen forest in Phu Khieo Wildlife Sanctuary, northeast Thailand . Nat Hist Bull Siam Soc 50(1): 75-88. Catchpole HR, van Wagenen G. 1975. Reproduction in the rhesus monkey, Macaca mulatta. In: Bourne GH, editor. The rhesus monkey: management reproduction, and pathology, Volume 2. New York : Academic Pr. 117-40.. Chapais B. 1986. Why do adult male and female rhesus monkeys affiliate during the birth season? In: Rawlins RG, Kessler MJ, editors. The Cayo Santiago macaques: history, behavior, and biology. Albany (NY): State Univ New York Pr. p 173-200. Deutsch JC, Lee PC. 1991. Dominance and feeding competition in captive rhesus monkeys. Int J Primatol 12(6): 615-28.. Dixson AF, Nevison CM. 1997. The socioendocrinology of adolescent development in male rhesus monkeys ( Macaca mulatta ). Horm Behav 31(2): 126-35).. Fan Z, Song Y. 2003. Chinese primate status and primate captive breeding for biomedical ...
To the Editor.-The article by Gamache and Myers (Arch Neurol 32:374, 1975) describing the effects of hypotension on Rhesus monkeys demands our comment not only
From the Back Cover The Rhesus Monkey Brain in Stereotaxic Coordinates is the most comprehensive, detailed atlas of the monkey brain ever constructed. The first chapter, Photographic and Diagrammatic Atlas of the Rhesus Monkey Brain, presents 151 plates illustrating the subcortex and parts of the cortex in high magnification, and 151 corresponding diagrams complementing each image. The second chapter, Delineation of the Rhesus Monkey Cortex on the Basis of the Distribution of a Neurofilament Protein, consists of 64 fully labeled plates depicting an entire hemisphere. Jointly, the two chapters constitute the most serious morphological work ever undertaken on the monkey. Key Features * Provides the first comprehensive delineations of cortical and subcortical structures of any primate species * Depicts the entire brain in 151 photographs paired with 151 detailed diagrams * Alternates sections stained for Nissl substance with sections reacted for acetylcholinesterase (AChE) * Contains 64 fully labeled
BACKGROUND: Exposure of the fetal or neonatal non-human primate (NHP) brain to isoflurane or ketamine for 5 h causes widespread apoptotic degeneration of neurones, and exposure to isoflurane also causes apoptotic degeneration of oligodendrocytes (OLs). The present study explored the apoptogenic potential of propofol in the fetal and neonatal NHP brain.. METHOD: Fetal rhesus macaques at gestational age 120 days were exposed in utero, or postnatal day 6 rhesus neonates were exposed directly for 5 h to propofol anaesthesia (n=4 fetuses; and n=4 neonates) or to no anaesthesia (n=4 fetuses; n=5 neonates), and the brains were systematically evaluated 3 h later for evidence of apoptotic degeneration of neurones or glia.. RESULTS: Exposure of fetal or neonatal NHP brain to propofol caused a significant increase in apoptosis of neurones, and of OLs at a stage when OLs were just beginning to myelinate axons. Apoptotic degeneration affected similar brain regions but to a lesser extent than we previously ...
Primate research animal. Head of an adult rhesus monkey (Macaca mulatta). This monkey may be used to study primate behaviour & biology, the development & transmission of human diseases, or to test novel drugs. Photographed at the New England Regional Primate Research Centre, Harvard Medical School, Massachusetts, USA. - Stock Image G352/0185
The SIV-infected rhesus macaque (Macaca mulatta) is the most established model of AIDS disease systems, providing insight into pathogenesis and a model system for testing novel vaccines. The understanding of cellular immune responses based on the identification and study of Major Histocompatibility Complex (MHC) molecules, including their MHC:peptide-binding motif, provides valuable information to decipher outcomes of infection and vaccine efficacy. Detailed characterization of Mamu-B*039:01, a common allele expressed in Chinese rhesus macaques, revealed a unique MHC:peptide-binding preference consisting of glycine at the second position. Peptides containing a glycine at the second position were shown to be antigenic from animals positive for Mamu-B*039:01. A similar motif was previously described for the Dd mouse MHC allele, but for none of the human HLA molecules for which a motif is known. Further investigation showed that one additional macaque allele, present in Indian rhesus macaques, Mamu-B*052
AbeBooks.com: Rhesus Monkeys / UK-Version 2017: Part B: The Rhesus Monkey (Macaca Mulatta) is a Primate of the Species of Macaques Within the Family Cercopithecidae (Calvendo Animals) (9781325152605) by Angelika Kimmig and a great selection of similar New, Used and Collectible Books available now at great prices.
Rhesus monkeys (Macaca mulatta) were experimentally infected with strains of simian immunodeficiency virus (SIV) derived from SIVmac239 lacking vpr, vpx, or both vpr and vpx genes. These auxiliary genes are not required for virus replication in cultured cells but are consistently conserved within the SIVmac/human immunodeficiency virus type 2/SIVsm group of primate lentiviruses. All four rhesus monkeys infected with the vpr deletion mutant showed an early spike in plasma antigenemia, maintained high virus burdens, exhibited declines in CD4+ lymphocyte concentrations, and had significant changes in lymph node morphology, and two have died to date with AIDS. The behavior of the vpr deletion mutant was indistinguishable from that of the parental, wild-type virus. Rhesus monkeys infected with the vpx deletion mutant showed lower levels of plasma antigenemia, lower virus burdens, and delayed declines in CD4+ lymphocyte concentrations but nonetheless progressed with AIDS to a terminal stage. The ...
Animals and virus. Of the 9 healthy, SIV-uninfected Indian RMs (Macaca mulatta) used in this study, 5 were Mamu-A*01+ and 4 were Mamu-A*01-. These animals were housed at the Yerkes National Primate Research Center and maintained in accordance with NIH guidelines. All animals were infected i.v. with 3,000 TCID50 SIVmac251 (provided by C. Miller, UCD, Davis, California, USA). Animals that reached disease endpoint, as defined by wasting syndrome unresponsive to therapy, were sacrificed according to the recommendations of the 2007 American Veterinary Medical Association (AVMA) Guidelines on Euthanasia. CD4+ lymphocyte depletion. 5 uninfected RMs (3 Mamu-A*01+, 2 Mamu-A*01-) were treated i.v. with 10 mg/kg humanized anti-CD4 mAb (Cdr-OKT4A-huIgG1; clone 12F11; provided by K. Reimann, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA) at days -57, -52, -47, and -45 relative to SIV infection. The efficacy of the depleting treatment in tissues in which absolute number calculations of the ...
Cannabis-related impairments to cognitive function may represent novel therapeutic targets for cannabis-use disorder, although the nature, persistence, and reversibility of those deficits remain unclear. Adult male rhesus monkeys (N=6) responded in the mornings on tasks designed to assess different cognitive domains using CANTAB touchscreens followed by responding maintained under a fixed-ratio (FR) 10 schedule of food presentation in different operant chambers. First, the acute effects of Δ9-tetrahydrocannabinol (THC; 0.01-0.56 mg/kg, i.v.) on cognitive performance, FR responding and body temperature were determined. Next, THC (1.0-2.0 mg/kg, s.c.) was administered daily after FR10 sessions for 12 weeks during which the residual effects of THC (i.e., 22 hrs after administration) on cognition were examined and the acute effects of THC were redetermined. In a subgroup of monkeys, dopamine D2/D3 receptor availability was assessed after 4 weeks of chronic THC exposure and compared to drug-naive ...
Purpose: To translate a recombinant peptide containing the amino-terminal fragment (ATF) of urokinase plasminogen activator receptor-targeted magnetic iron oxide (IO) nanoparticles (uPAR-targeted human ATF-IONPs) into clinical applications, we conducted a pilot study to evaluate the toxicity and pharmacokinetics of this nanoparticle in normal rhesus monkeys. Methods: We assessed the changes in the following: magnetic resonance imaging (MRI) signals from pretreatment stage to 14 days posttreatment, serum iron concentrations from 5 minutes posttreatment to 12 weeks posttreatment, routine blood examination and serum chemistry analysis results from pretreatment stage to 12 weeks after administration, and results of staining of the liver with Perls Prussian Blue and hematoxylin-eosin at 24 hours and 3 months posttreatment in two rhesus monkeys following an intravenous administration of the targeted nanoparticles either with a polyethylene glycol (ATF-PEG-IONP) or without a PEG (ATF-IONP) coating. ...
rakesh kumar pharmacology and behaviour of rhesus monkey macaca mulatta в наличии / купить в один клик в нашем интернет- ...
Chronic stress has been associated with degenerative changes in the rodent and primate hippocampus, presumably mediated in part via neuronal glucocorticoid receptors (GRs). In the rat brain, GRs are widely distributed and are particularly dense in the hippocampus. The distribution of GRs in the primate brain, however, has not been fully characterized. In this study, we used in situ hybridization histochemistry and immunohistochemistry to map the distribution of GR mRNA and GR protein, respectively, in adult rhesus monkeys (Macaca mulatta). In contrast to its well established distribution in the rat brain, GR mRNA was only weakly detected in the dentate gyrus (DG) and Cornu Ammonis (CA) of the macaque hippocampus, whereas it was abundant in the pituitary (PIT), cerebellum (CBL), hypothalamic paraventricular nucleus (PVN), and, to a lesser extent, the neocortex. Immunohistochemical staining indicated a very low density of GR-like immunoreactive cells within the macaque hippocampal formation in ...
Macaca mulatta Mamu-B 01 antigen: a MHC class I B locus allele-restricted similan immunodeficiency virus envelope CTL epitope in rhesus monkeys; amino acid sequence given in first source
... - MADISON, Wis. - University of Wisconsin-Madison researchers studying monkeys have shown that one infection with Zika virus protects against future infection, though pregnancy may drastically prolong the time the virus stays in the body.. The researchers, led by UW-Madison pathology Professor David OConnor, published a study today (June 28, 2016) in the journal Nature Communications describing their work establishing rhesus macaque monkeys at the Wisconsin National Primate Research Center as a model for studying the way Zika virus infections may progress in people.. The team of UW and Duke University scientists - which includes specialists in emergent and insect-borne diseases, genetics and immunology, pediatrics and pregnancy - have been working with infected monkeys for months.. "What weve shown in the monkey model matches a lot of what people have observed in epidemiological studies of humans," says Emma Mohr, a pediatric infectious disease fellow at UW-Madison and first author on ...
Background: Vincristine has been used as standard therapy for adult and pediatric malignancies for 50 years. Cumulative neurotoxicity often requires capping the maximum single and cumulative VCR dose. VSLI is a novel preparation of VCR encapsulated in sphingomyelin/cholesterol liposomes. Following clinical trials that demonstrated safety, tolerability and efficacy in adults with relapsed/refractory acute lymphoblastic leukemia, VSLI has been granted FDA accelerated approval at a dose of 2.25 mg/m2given once weekly for that population. A pediatric Phase I trial is ongoing. We evaluated plasma and CSF PK of intravenously (IV) administered VCR and total VSLI (liposomal encapsulated and non-encapsulated) in our NHP model.. Methods: 0.1 mg/kg (1.2 mg/m2 human-equivalent dose) VCR over 1 minute or VSLI over 15 minutes was administered on separate occasions to each of 3 adult rhesus monkeys (Macaca mulatta). Serial paired plasma and CSF samples were collected for up to 48 hrs. Drug concentrations were ...
The relationship between α-tocopherol, a known antioxidant, and polyunsaturated fatty acid (PUFA) oxidation, has not been directly investigated in the primate brain. This study characterized the membrane distribution of α-tocopherol in brain regions and investigated the association between membrane α-tocopherol and PUFA content, as well as brain PUFA oxidation products. Nuclear, myelin, mitochondrial, and neuronal membranes were isolated using a density gradient from the prefrontal cortex (PFC), cerebellum (CER), striatum (ST), and hippocampus (HC) of adult rhesus monkeys (n = 9), fed a stock diet containing vitamin E (α-, γ-tocopherol intake: ~0.7 µmol/kg body weight/day, ~5 µmol/kg body weight/day, respectively). α-tocopherol, PUFAs, and PUFA oxidation products were measured using high performance liquid chromatography (HPLC), gas chromatography (GC) and liquid chromatography-gas chromatography/mass spectrometry (LC-GC/MS) respectively. α-Tocopherol (ng/mg protein) was highest in nuclear
British Publication, The Daily Mirror is reporting that a vaccine which could completely clear the body of all traces of the Aids virus has been developed.". "Scientists have successfully controlled the disease in monkeys, raising hopes they may finally conquer the human form," the report goes on to say.. This large experimental study was in 67 male rhesus macaque monkeys that were given the monkey form of HIV, called Simian Immunodeficiency Virus (SIV). The vaccine was tested in 24 monkeys, 13 of which showed complete control over the SIV virus. Further analysis showed that 12 of these were still protected after a year. In contrast, macaques that did not get the vaccine continued to show high levels of the virus.. This research has re-ignited debate within the research community that a HIV vaccine for humans may be possible. Experts have called this early research exciting and described it as a breakthrough. The technique will now need to be adapted to see if it can be used in treating ...
The present experiments provide some insight into the time course of perceptual learning for chromatic targets. Access to this information is difficult to obtain from previous comparative experiments, which often used aversive conditioning that over time engenders a long-term avoidance response to the testing situation. The present results show that subjects needed a variable number of sessions to reach plateau performance for different colors, but that the range was the same between monkey and human subjects (one to seven sessions). Monkeys and humans also showed similar variability in the number of sessions necessary to reach plateau performance (SD = 1.9 for monkeys, 1.8 for humans). Once plateau performance was achieved, optimal performance was maintained across long time gaps in task activity (Supplementary Figure S2). The results show a striking asymmetry in the improvement in performance over training for the +S versus −S targets for both humans and monkeys: the learning effect for +S ...
The rhesus monkey (Macaca mulatta) is conventional for biomedical and mental reports. consequently, an incredible fund of clinical details comes in papers and a few gathered facts. This booklet is mostly a suite of knowledge from over 2000 papers on rhesus monkey. It covers subject matters at the cerebral angiography, electrocardiogram, and vector cardiogram of the rhesus monkey. It additionally offers more information on morphology and serve as of rhesus kidney; the improvement and eruption of tooth in rhesus; and the histology and histochemistry of the rhesus monkey ...
In response to the recent emergence of Zika virus (ZIKV) in North and South America, there is an urgent need for animal models to test vaccines and therapeutics against this zoonotic pathogen. Non-human primates models are often needed for vaccine and immunomodulatory therapeutic evaluation due to their close evolutionary proximity to humans and the similarity of their physiology and immunology. IITRI has developed a Rhesus macaque Zika infection model for the preclinical testing of vaccines and antiviral therapeutics. ###Experimental Summary###
Subjects. Five male rhesus monkeys (Macaca mulatta) were used in studies of schedule-controlled responding, three male monkeys were used in studies of thermal nociception, three male and female monkeys were used in the single-key assay of drug self-administration, and three male monkeys were used in studies of food versus drug choice. Subjects weighed 4.5 to 12 kg during the course of these studies. All monkeys had prior exposure to drugs (primarily dopaminergic and opioid compounds) and to the behavioral procedures in which they were tested. The subjects were individually housed, and water was freely available. Their diet consisted of PMI Feeds Jumbo monkey diet (two to six biscuits per day; PMI Feeds, Inc., St. Louis, MO). This diet was supplemented with fresh fruit twice daily. In addition, monkeys in the assays of schedule-controlled behavior and food versus drug choice could earn additional food pellets during experimental sessions. A 12-h light/12-h dark cycle was in effect (lights on from ...
Self-recognition in front of a mirror is used as an indicator of self-awareness. Along with humans, some chimpanzees and orangutans have been shown to be self-aware using the mark test. Monkeys are conspicuously absent from this list because they fail the mark test and show persistent signs of social responses to mirrors despite prolonged exposure, which has been interpreted as evidence of a cognitive divide between hominoids and other species. In stark contrast with those reports, the rhesus monkeys in this study, who had been prepared for electrophysiological recordings with a head implant, showed consistent self-directed behaviors in front of the mirror and showed social responses that subsided quickly during the first experimental session. The self-directed behaviors, which were performed in front of the mirror and did not take place in its absence, included extensive observation of the implant and genital areas that cannot be observed directly without a mirror. We hypothesize that the head implant,
Specific staining protocols10,11 were as follows: Our DeOlmos cupric silver method and nonfluorescent staining methods for AC3 have been described previously.4,8-12 For MBP (1:100; MAB 395; EMD Millipore, Billerica, MA), fractin (1:400; AB3150; EMD Millipore), Iba1 (1:500; 019-18741; Wako Chemicals, Richmond, VA), and CC-1 (1:200; OP80; Calbiochem, San Diego, CA) immunostaining methods, we used the Vectastain Elite ABC kit with Vector VIP as chromogen (Vector Laboratories, Inc., Burlingame, CA).4,8-12 Immunofluorescent detection of caspase-mediated cell death employed an AC3 rabbit primary polyclonal antibody (9661B; 1:500; Cell Signaling Technology, Inc., Danvers, MA). Floating sections were incubated overnight at room temperature. After the sections were rinsed in phosphate-buffered saline (3 × 5 min) they were incubated for 2 h at room temperature with fluorescent goat antirabbit Alexa Fluor 555 (1:1,000, Invitrogen™, Life Technologies™, Grand Island, NY), rinsed in phosphate-buffered ...
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The rhesus macaque (Macaca mulatta) and human (Homo sapiens) are thought to have shared a common ancestor approximately 25 million years ago [1]. Due to their genetic, physiological and behavioral similarities with humans, and because of their hardiness, adaptability, and availability, the rhesus macaque has been widely used as a model in biomedical research [2, 3]. Humans presently are the most numerous and widespread of primates. Furthermore hominid apes representing the ancestral lineage of humans were geographically widespread, their fossils having been found in both Africa and Asia. However the human diaspora is relatively recent, with our African ancestry dating back only 80,000 to 150,000 yrs b.p [4]. Also, the number of humans worldwide numbered as low as one million as recently as 100,000 yrs ago [5], and due to limitations in dispersion and gene flow effective population sizes were much smaller still. Substantial evidence exists that the neutral genetic diversity of humans has been ...
Recorded amongst childrens artwork and toys the tracks contain an immediacy and vibrancy fresh from the bands infamous live shows. The album is currently available for download through Indiestore from the following sites : indiestore.7digital.com/antescene www.myspace.com/macacamulatta www.macacamulatta.com www.last.fm/music/Macaca+Mulatta/AAA www.facebook.com/group.php?gid=13433641471 To compliment the online release, artwork and lyrics will be available for download, allowing purchasers to create their own CDs if they so wish. (www.macacamulatta.com/aaa_artwork.zip) The album will be available through iTunes, napster, Amazon and many more sites in the near future, as will a physical release complete with a limited edition scrabble piece cover. A video release of the album is pencilled for release later in the year, so all budding film makers should get in touch if they want to contribute. All members of the band will be involved in future music projects, with Chris Chinchilla and Estafan ...
Read more about Indian-origin man jailed 10 yrs for killing woman in Spore on Business Standard. A 32-year-old Indian-origin man was today sentenced to 10 years of jail and 12 strokes of the cane for murdering a woman 16 years ago during an attempt to rob her at knife-point in a lift. Gunasegaran Ramasamy was sentenced to the maximum 10 years
Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG that promote DC maturation.
Receptor for a C-C type chemokine. Binds to eotaxin, MCP-3, MCP-4 and RANTES and subsequently transduces a signal by increasing the intracellular calcium ions level.
MXC will be administered orally to female rhesus monkeys at 2 dose levels from 24 mos of age (approximately equivalent to 8 y of age in humans) to 39 mos of age (14 y in humans). After dosing, the young monkeys will be allowed to recover until the age of full sexual maturation (45 months, 16 y in humans) and then examined for successful completion of adolescence in terms of growth, ovarian cyclicity, reproductive tract morphology and histology, brain development and immune function. Noninvasive methods such as brain EEG, bone scans, urine hormone measures, colposcopy, and characterization of lymphocyte populations in peripheral blood samples will be used. Diethyl stilbestrol (DES) will serve as a positive control. The project period is 3 years. ...
It is controversial whether damage to prefrontal cortex causes an impairment of memory. In this experiment, the tissue in sulcus principalis was removed in rhesus monkeys, and they were given 25 spatial locations to remember. They were poor at the task from the first. The same animals were able to indicate which of two locations they had touched if there was no delay before they were allowed to make their report. One possibility is that frontal mechanisms operate on information in working memory.
Figure 2. Assessment of B- and T-cell phenotype and function in peripheral blood (PB). For flow cytometric analysis, PB mononuclear cells were labeled with following pre-titrated fluorochrome-conjugated Ab combinations (if not otherwise stated from BD Biosciences): CD3 (SP34-2), CD4 (L200), CD19 (J3-119, Beckman Coulter), CD20 (L27), CD27 (MT271), CD28 (CD28.2), CD38 (AT.1, StemCell), CD95 (DX2), CD138 (DL-101), and IFN-γ (5 mg/mL B27). Further, a Live/Dead© probe (Life Technologies) was used. For detection of intracellular T cell IFN-γ, PBMCs were activated with 5 ng/mL Phorbol 12-myristate 13-acetate (PMA) and 1 μg/mL Ionomycin (both from Sigma-Aldrich) in the presence of protein transport-inhibitor monensin (BD Biosciences). Data were acquired with BD LSR II and analyzed with FlowJo (v.10, TreeStar Inc.). (A) Representative B-cell and (B) T-cell gating on day 73 where B cells were defined as viable CD3‒, CD19+, CD28−, CD20+/− single cells; memory B cells (MBCs) as CD27+ B cells and ...
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Some of the first HIV vaccines were designed to trigger neutralizing antibody responses as a way to prevent HIV infection. Unfortunately, the first versions of these vaccines were not able to achieve their desired response. An alternative strategy to the antibody approach is the stimulation of HIV-specific CD8 T-lymphocyte (CTL) responses. CTL responses were previously demonstrated to play an important role in the control of simian immunodeficiency virus (SIV), the HIV equivalent studied in rhesus macaque monkeys. Additionally, other studies suggest CTLs play an important role in viral control during chronic infection. Based on this information, several groups have shifted their focus to the development of CTL-based vaccines, some of which have entered advanced clinical trials.. A DNA/rMVA vaccine strategy is structured to bring about both T cell and antibody responses. The primary vaccination is DNA based and will express only HIV proteins as a way to produce an HIV-focused immune response. A ...
Some of the first HIV vaccines were designed to trigger neutralizing antibody responses as a way to prevent HIV infection. Unfortunately, the first versions of these vaccines were not able to achieve their desired response. An alternative strategy to the antibody approach is the stimulation of HIV-specific CD8 T-lymphocyte (CTL) responses. CTL responses were previously demonstrated to play an important role in the control of simian immunodeficiency virus (SIV), the HIV equivalent studied in rhesus macaque monkeys. Additionally, other studies suggest CTLs play an important role in viral control during chronic infection. Based on this information, several groups have shifted their focus to the development of CTL-based vaccines, some of which have entered advanced clinical trials.. A DNA/rMVA vaccine strategy is structured to bring about both T cell and antibody responses. The primary vaccination is DNA based and will express only HIV proteins as a way to produce an HIV-focused immune response. A ...
MA-104 was developed by initial explant culture and subsequent passage by enzymatic dissociation at Microbiological Associates from embryonic Rhesus monkey kidney tissue.
Thankfully, recent animal studies have led to improvements in available vaccines, as well as new prevention methods that might be used in the future to bridge the vaccination gap-whether its caused by limited access for people living in the developing world, or by parental suspicions about vaccines in the west. Researchers typically begin with cell cultures and embryos, thereafter testing drug therapies in species like mice, rodents, and rabbits before moving to larger non-human primate models. These studies, which are credited with paving the way for vaccinations against diseases like polio, measles, and rubella, have contributed to the body of medical knowledge a comprehensive understanding of how immunizations work.. Recent research, especially with primate models, has offered a more complete picture of the human immune system that has improved existing vaccines while proving their safety and effectiveness in people. For example, it was a study with rhesus macaque monkeys that led scientists ...
The "hundredth monkey" tale first surfaced in the late 1970s, in Lifetide (Simon & Schuster, 1979), by New Age scientist Lyall Watson. Then, in 1982, Ken Keyes Jr. popularized the parable in The Hundredth Monkey (Vision Books), an anti-nuclear-war treatise that sold more than 1 million copies. The monkey myth, as recounted by Keyes, goes like this: On an island near Japan, scientists distributed sandy sweet potatoes to a colony of monkeys. Soon one young monkey learned how to wash the sand off the potatoes before eating them. She taught the trick first to her mother and then to other young monkeys. More and more young monkeys started teaching their parents how to wash sweet potatoes. One day, the 100th monkey learned how to wash the sandy spuds -- and at that moment, miraculously, all of the monkeys started washing their potatoes. Even more amazing, the potato-washing practice leapt over land and sea: Monkeys on other islands were suddenly washing their food too. According to Keyes, the story ...
University of Wisconsin and NICHD Introduction Rhesus macaque infants typically form strong attachments to their mothers or mother substitutes within the first weeks of life (Harlow & Harlow, 1965). The work of Mason and his colleagues (Mason & Kenney, 1974; Mason & Capitanio, 1988) has demonstrated that rhesus monkeys reared with dogs or inanimate surrogates are capable of redirecting their attachment following separation from the initial attachment figure. However, the possibility of transferral of the attachment bond has not been empirically tested in mother-reared monkey infants. In free-ranging rhesus, individuals other than the mother may provide infant care (Berman, 1982). Whereas redirection of attachment may occur under these conditions, it is unclear whether the bond with the original filial attachment source remains intact, or if the attachment to the new caregiver supercedes the previous filial bond. The present study investigated whether yearling rhesus monkeys which had been living ...
Neuropeptides are a diverse assemblage of signalling molecules that have key roles in the regulation of behaviour. Understanding the evolutionary relationships and functions of the plethora of neuropeptides has presented a considerable challenge to biologists. Based on presentations and discussions at a Royal Society meeting in 2017, three companion Review articles by Elphick et al., Jékely et al. and DeLaney et al. discuss advances in our knowledge of neuropeptide evolution and function and the techniques that have facilitated progress in this field of research.. ...
Read more about Chronic stress of life alters immune system: Study on Business Standard. A new study conducted on rhesus monkey shows that the chronic stress of life at the bottom can alter the immune system even in the absence of other risk factors.The research confirms previous animal studies suggesting that social status affects the
Record removed. This record was removed because the RefSeq project is no longer calculating annotation updates for the Mmul_051212 assembly. ...
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Propecia is only prescribed for men. Women and children should not only avoid consuming it, but they should also avoid handling the tablets, especially pregnant women. Finasteride can be absorbed through the skin and can cause birth defects if pregnant women are exposed to it, including abnormalities of the external genitalia in a male foetus.. For men taking Propecia trace amounts of the finasteride have been detected in their seminal fluid - 0.001% per ejaculation for men on the 1mg dosage. Studies on Rhesus monkeys have been carried out, and so far there is no research to suggest these levels provide any risk to a developing male foetus. Any long term impact on fertility is not yet known, but there is no evidence currently to suggest that it has any negative impact.. ...
Make money tips. Focus and Fear of Success - The Biggest Monkey on Your Back?.. All about Make money. Recommended Reading Make money articles.
December 18, 2017 An Indian-origin Barclays Bank employee from London has been jailed for over six years for his role in a conspiracy to launder over 2.5 million pounds. Jinal Pethad used the Dridex Trojan malware in the scam, which involved the 29-year-old acting as the personal bank manager to money launderers
An Indian-origin researcher is investigating the use of CT (Computed Tomography) scanning for patients suffering from severe asthma.
Health,WINSTON-SALEM N.C. Monkeys get depressed too and scientists hope...The scientists found that depressed female monkeys become socially wit...,Researchers,hope,monkeys,can,provide,new,insights,into,depression,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Subjects and task. The experiments (33 on each monkey) were performed on two adult female monkeys (Macaca mulatta) (M7, 6 kg; M8, 5 kg) trained previously to perform oculomotor tasks (Courtemanche et al., 2001; Fujii and Graybiel, 2001; Blazquez et al., 2002). Each monkey had an eye coil implanted in one eye to measure eye displacement (Fuchs and Robinson, 1966), a head bolt for head fixation, and a recording chamber that could be fitted with a grid for microelectrode placement. The chamber of monkey M7 was aligned with the horizontal plane, centered at stereotypic anterior coordinate A20, and allowed bilateral recordings; the chamber of M8 was implanted on the left side at a 20° angle from the sagittal plane and was centered at A21. The monkeys either rested or performed a visually guided single-saccade task in which the monkey faced a computer screen with a 9 × 9 array of gray dots. The monkeys task was first to fixate the central dot for a period of 700 msec to 1 sec. Feedback to the ...
Purified Recombinant Rhesus monkey APEX1 Protein, His-tagged from Creative Biomart. Recombinant Rhesus monkey APEX1 Protein, His-tagged can be used for research.
Flt3 Ligand Rhesus Macaque Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 159 amino acids and having a molecular mass of 18.0kDa.
Health, ...THURSDAY Dec. 27 (HealthDay News) -- Rhesus monkeys cannot hear the...The findings support the view that this ability -- known as beat induc...For the study published recently in the journal PLoS One the ...While the monkeys were unable to pick up the beat in music they were ...,Are,Rhesus,Monkeys,Musically,Challenged?,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
These and other nucleic acids are being delivered using the amaxa, Inc Nucleofection technology. This approach is being used for the development of reagents useful in investigations involving the rhesus macaque model of AIDS; the structural and functional relationships of the inhibitory effects of IL-16; and translation of these to cellular and cytokine therapeutic modalities. ...
Erika Sasaki and Hideyuki Okano of the Keio University School of Medicine in Japan used a virus to carry the gene for green fluorescent protein into monkey embryos, which were implanted into a female monkey, and four out of five were born with the gene throughout their bodies ...
The current study validates a robust method to confidently characterize the proteins from an incomplete sequence database of Macaca mulatta
Conceptual abilities in animals have been shown at several levels of abstraction, but it is unclear whether the analogy with humans results from convergent evolution or from shared brain mechanisms inherited from a common origin. Macaque monkeys can
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July 13, 1953: I had a sudden burst of inspiration. The rats were all killed by the chemicals on their cards, the monkeys were all crushed under the weight of other monkeys, Svarkin was killed because he betrayed his heritage, and Kolesnikov killed himself out of depression. The machine has, in every case, described the manner in which the subject dies. The only way I can prove this theory is by attempting - and, ideally, failing - to disprove it. I tried suggesting to the scientists that we test a large number of animals and attempt to kill them in a manner different from that described on their card, but they would have none of it, given Codename Fours orders. I tried going to Codename Four himself, but he was in a meeting with J. Edgar Hoover all day - and Hoover was furious. I would simply have to sneak out at night and test myself - and then do everything in my power to stay alive. At the very least, this would provide me with food for thought until I have time to perform the animal tests ...
A recently published monkey study showed complete protection in half of the rhesus monkeys included after they were exposed to SIV, a virus similar to HIV ...
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Monkey (Rhesus) Normal Tissue: Ureter, 1 mg. Tissue total protein is prepared from whole tissue homogenates and presents a consistent pattern on SDS-PAGE analysis.
The transplant core (Core B) is crucial for all three projects in this proposal. The mission of this core is to provide the high quality rhesus macaques of appr...
Monkeys for sale. Although it might be nice, there are many reasons why buying a pet monkey is not a good idea. Its expensive, dangerous and not good for you or the monkey.
Ο παράγοντας Rhesus είναι μία πρωτεΐνη που μπορεί να υπάρχει ή όχι στην επιφάνεια των ερυθροκυττάρων ενός ατόμου. Τα άτομα που έχουν αυτή την πρωτεΐνη χαρακτηρίζονται ως Rhesus θετικά (Rh+). Η παρουσία αντιγόνου (παράγοντας Rhesus) συγχρόνως με το αντίστοιχο αντίσωμα (αντί-Rh), (όπως όταν μια έγκυος μητέρα είναι ήδη ευαισθητοποιημένη -έχει αντισώματα έναντι του παράγοντα Rh, αν το επόμενο έμβρυο είναι πάλι Rh+, θα πεθάνει, γιατί τα ερυθροκύτταρά του θα καταστραφούν από τα αντισώματα της μητέρας που διοχετεύονται μέσω του πλακούντα στην κυκλοφορία του εμβρύου), ...
Rhesus monkey rhadinovirus (RRV) is a close relative of Kaposis sarcoma-associated herpesvirus (KSHV; human herpesvirus 8). RRV serves as an in vitro and an in vivo model for KSHV, and the mapping of its transcription program during lytic replication is significant since it represents de novo infection in the absence of stimulation with phorbol esters. Further, the RRV lytic system facilitates the making of recombinant viruses, and hence transcription profiling of the wild-type virus is important. Currently, the kinetics of lytic gene expression of RRV, the function of the RRV Orf50/Rta gene, and the presence of the RRV R8 and R8.1 genes are not known. This study details the transcription profile seen during RRV lytic replication and shows that RRV latency-associated nuclear antigen, viral FLIP (vFLIP), and vCyclin are transcribed during the RRV lytic phase. In addition, this study describes the identification of three new spliced products of the RRV Orf50, R8, and R8.1 genes, which are ...
Agrillo C., Gori S., Beran M.J. (2015). Do rhesus monkeys (Macaca mulatta) perceive illusory motion? Animal Cognition. Abstract. During the last decade, visual illusions have been used repeatedly to understand similarities and differences in visual perception of human and non-human animals. However, nearly all studies have focused only on illusions not related to motion perception, and to date, it is unknown whether non-human primates perceive any kind of motion illusion. In the present study, we investigated whether rhesus monkeys (Macaca mulatta) perceived one of the most popular motion illusions in humans, the Rotating Snake illusion (RSI). To this purpose, we set up four experiments. In Experiment 1, subjects initially were trained to discriminate static versus dynamic arrays. Once reaching the learning criterion, they underwent probe trials in which we presented the RSI and a control stimulus identical in overall configuration with the exception that the order of the luminance sequence was ...
How the captive environment influences the behavior of animals is relevant to the well-being of captive animals. Captivity diverges from the natural environment in many ways, and one goal of enrichment practices is to encourage species-typical behavior in these unnatural environments. This study investigated the influence of grass vs. gravel substrate on activity budgets and degree of hair loss in seven groups of captive rhesus macaques housed in outdoor enclosures at the California National Primate Research Center. Groups having grass substrate spent a greater proportion of their time foraging and a smaller proportion of time grooming compared with groups having gravel substrate. Increased time spent grooming in gravel enclosures may have contributed to significantly greater hair loss in those enclosures. A causal relationship between ground substrate on foraging and grooming, and therefore hair loss, is strengthened by similar changes in activity budgets and hair loss in a single group that ...
Recent analyses of association fibre networks in the primate cerebral cortex have revealed a small number of densely intra-connected and hierarchically organized structural systems. Corresponding analyses of data on functional connectivity are required to establish the significance of these structural systems. We therefore built up a relational database by systematically collating published data on the spread of activity after strychnine-induced disinhibition in the macaque cerebral cortex in vivo. After mapping these data to two different parcellation schemes, we used three independent methods of analysis which demonstrate that the cortical network of functional interactions is not homogeneous, but shows a clear segregation into functional assemblies of mutually interacting areas. The assemblies suggest a principal division of the cortex into visual, somatomotor and orbito-temporo-insular systems, while motor and somatosensory areas are inseparably interrelated. These results are largely ...
Behavioral observations on a large group of free-ranging rhesus monkeys (Macaca mulatta) were carried out on Cayo Santiago from January I968 through December I969 and from October through December I970. Records of mating activity (single mounts, mount series, copulations) indicated that genealogical mating activity on Cayo Santiago had the following characteristics : (I) 5.4% of all recorded mount series and copulations involved mother-son pairs; (2) mating was observed in 3I% of 26 individual pairs of mothers and sons; (3) mating was seen in I2% of 42 individual pairs of brothers and sisters; (4) of I0 instances of mother-son mating, seven involved pairs in which the mother was dominant to the son; (5) mating in mother-son and brother-sister pairs occurred in high and low ranking genealogies within the group; (6) with two exceptions, all three to five-year old males who did engage in sexual activity with their mothers did not mate with non-related females during that breeding season; and (7) with one
Recent preliminary data suggest that vaccination with Alzheimers Abeta might reduce senile plaque load and stabilize cognitive decline in human Alzheimers disease. To examine the mechanisms and consequences of anti-Abeta-antibody formation in a species more closely related to humans, rhesus monkeys (Macaca mulatta) were vaccinated with aggregated Abeta(1-42). Immunized monkeys developed anti-Abeta titers exceeding 1:1000, and their plasma Abeta levels were 5-10-fold higher than the plasma Abeta levels observed in monkeys vaccinated with aggregated amylin. These data support the use of non-human primates to model certain phenomena associated with vaccination of humans with aggregated Alzheimers Abeta. ...
We studied the association between social rank and sexual behaviour in a group of rhesus monkeys (Macaca mulatta) (10 males, 14 females) housed in two adjacent 15.25 x 15.25 m compounds which were separated by a solid metal wall. This wall had a small opening through which the monkeys could move from one compound to another. Because of the position of this opening, most monkeys in one compound were hidden from view of the monkeys that remained in the other compound. It was therefore possible for an observer to record whether sexual behaviour was initiated within or outside the field of view of the four highest ranking animals (two males and two females). About 2/3 of the mount sequences initiated by lower ranking males were begun when the dominant animals were out of view. Such behaviour was usually disrupted if dominant animals entered the compound in which it was taking place. Most disruptions of sexual behaviour were accomplished by means of aggression directed by a dominant animal toward one or both
The aim of this study was to characterize pediatric pharmacokinetics and central nervous system exposure of naproxen after oral administration. The pharmacokinetics of naproxen was studied in 53 healthy children aged 3 months to 12 years undergoing surgery with spinal anesthesia. Children received preoperatively a single dose of 10 mg/kg oral naproxen suspension. A single cerebrospinal fluid (CSF) sample (n = 52) was collected at the induction of anesthesia, and plasma samples (n = 270) were collected before, during, and after the operation (up to 51 hours after administration). A population pharmacokinetic model was built using the NONMEM software. Naproxen concentrations in plasma were well described by a 2-compartment model. The estimated oral clearance (CL/F) was 0.62 L/h when linearly scaled by weight to 70 kg. The apparent volume of distribution at steady state (Vss/F) was 12.5 L/70 kg. The findings are consistent with previously reported pharmacokinetic parameters for children older than ...
This trial will invwsigate the pharmacokinetics of daptomycin in patients with external ventricular drain related meningitis or ventriculitis.
Macaca fascicularis (cynomolgus, crab-eating, or long-tail macaque) is one of the most popular primate species used in biomedical research, and is closely related to Macaca mulatta (rhesus macaque). The draft sequence of the Macaca mulatta genome, which has an evolutionary important position, was published in 2007 [1].. Transcriptiome data broadens the application of genome sequences. Compared with several millions of human transcript sequences, macaque transcriptome data has only been analyzed in a limited numbers of studies [2-6]. A complete list of macaque genes will be beneficial for performing genetic studies using macaques in the future. We aim to elucidate all the macaque transcripts that correspond to human genes, which have been widely accepted as reference sequences, such as the RefSeq sequences [7].. We have published expressed sequence tag (EST) and full-length sequences, which were obtained from cDNA libraries of brain and testis of Macaca fascicularis, using a variety of research ...
TY - JOUR. T1 - Decreases in Electrocardiographic R-Wave Amplitude and QT Interval Predict Myocardial Ischemic Infarction in Rhesus Monkeys with Left Anterior Descending Artery Ligation. AU - Sun, Xiaorong. AU - Cai, Jindan. AU - Fan, Xin. AU - Han, Pengfei. AU - Xie, Yuping. AU - Chen, Jianmin. AU - Xiao, Ying. AU - Kang, Yujian. PY - 2013/8/13. Y1 - 2013/8/13. N2 - Clinical studies have demonstrated the predictive values of changes in electrocardiographic (ECG) parameters for the preexisting myocardial ischemic infarction. However, a simple and early predictor for the subsequent development of myocardial infarction during the ischemic phase is of significant value for the identification of ischemic patients at high risk. The present study was undertaken by using non-human primate model of myocardial ischemic infarction to fulfill this gap. Twenty male Rhesus monkeys at age of 2-3 years old were subjected to left anterior descending artery ligation. This ligation was performed at varying ...
Polymeric immunoglobulin receptors(pIgR) are key participants in the formation and secretion of secretory IgA(S-IgA), which is critical for the prevention of microbial infection and colonization in the respiratory system. Although increased respiratory colonization and infections are common in HIV/AIDS, little is known about the expression of pIgR in the airway mucosa of these patients. To address this, the expression levels of pIgR in the tracheal mucosa and lungs of SHIV/SIV-infected rhesus macaques were examined by real-time RTPCR and confocal microscopy. We found that the levels of both PIGR mRNA and pIgR immunoreactivity were lower in the tracheal mucosa of SHIV/SIV-infected rhesus macaques than that in non-infected rhesus macaques, and the difference in pIgR immunoreactivity was statistically significant. IL-17A, which enhances pIgR expression, was also changed in the same direction as that of pIgR. In contrast to changes in the tracheal mucosa, pIgR and IL-17A levels were higher in the ...
An additional series of mutational analyses revealed a fine specificity for the lipopeptide recognition by the T cells. The 5-mer Nef peptide conjugated with a shorter (C10) saturated fatty acid (C10-GGAIS) showed reduced T cell stimulation activity compared with C14nef5, and no T cell response was detected for C6-GGAIS (Fig. 1F), further confirming that the peptide modification with a fatty acid of the C14 chain length (myristic acid) was essential for activation of the 2N5.1 cells. The N-terminal amino acid sequence (GGAIS) of the Nef protein matches with a typical N-myristoylation motif, Gly-X-X-X-(Ser/Thr), in which X is any amino acid (3). Whereas the serine-to-threonine substitution (C14-GGAIT) did not affect the antigenic activity, alanine substitution for either the second glycine residue (C14-GAAIS) or the isoleucine residue (C14-GGAAS) located between the conserved flanking amino acid residues totally abrogated the activity (Fig. 1F). Furthermore, addition of an amide linkage to the ...
In adult rhesus monkeys a two- to threefold increase in the number of spermatogonia was found at Day 75 after 1 Gy of X-irradiation when the animals were pretreated with two intramuscular injections of follicle-stimulating hormone (FSH) each day. Also the percentage of cross-sections of seminiferous tubules showing spermatogonia (repopulation index) was much higher when FSH was given before irradiation. At 75 days postirradiation the repopulation index was 39 ± 10% after irradiation alone and 81 ± 11% when FSH pretreatment was applied.. The pretreatment with two injections of FSH each day during 16 days caused an increase in the number of proliferating A spermatogonia. In view of earlier results in the mouse, where proliferating spermatogonial stem cells appeared more radioresistant than quiescent ones, it is suggested that the protective effects of FSH treatment are caused by the increase in the proliferative activity of the A spermatogonia and consequently of the spermatogonial stem ...
Among the animal models of tuberculosis (TB), the non-human primates (NHPs), particularly rhesus macaques (Macaca fascicularis) and cynomolgus macaques (Macaca mulatta), share the greatest anatomical and physiological similarities with humans. Macaques are highly susceptible to Mycobacterium tuberculosis infection and manifest the complete spectrum of clinical and pathological manifestations of TB as seen in humans. Therefore, the macaque models have been used extensively for investigating the pathogenesis of M. tuberculosis infection and for preclinical testing of drugs and vaccines against TB. This review focuses on published major studies that exemplify how the rhesus and cynomolgus macaques have enhanced and may continue to advance global efforts in TB research.
Immunization of rhesus macaques with strains of simian immunodeficiency virus (SIV) that are limited to a single cycle of infection elicits T-cell responses to multiple viral gene products and antibodies capable of neutralizing lab-adapted SIV, but not neutralization-resistant primary isolates of SIV. In an effort to improve upon the antibody responses, we immunized rhesus macaques with three strains of single-cycle SIV (scSIV) that express envelope glycoproteins modified to lack structural features thought to interfere with the development of neutralizing antibodies. These envelope-modified strains of scSIV lacked either five potential N-linked glycosylation sites in gp120, three potential N-linked glycosylation sites in gp41, or 100 amino acids in the V1V2 region of gp120. Three doses consisting of a mixture of the three envelope-modified strains of scSIV were administered on weeks 0, 6, and 12, followed by two booster inoculations with vesicular stomatitis virus (VSV) G trans-complemented scSIV on
Five Chinese rhesus macaques which received decellularized porcine corneal lamellae and were followed up for at least 6 months underwent full-thickness corneal allotransplantation. Previous xeno-grafts (7.5mm in diameter) were removed with 8.0mm trephines and 8.5mm-sized grafts from donor macaques were transplanted. Clinically applicable minimal immunosuppression was done based on topical, subconjunctival and systemic corticosteroids. Rejection signs and serial changes in recipients blood profile, including memory T cell subset, anti-Gal and donor pig specific antibodies, and complement were evaluated. Changes in aqueous complement concentration were also assessed at 4 weeks after transplantation. The mixed lymphocytes reaction (MLR) was analyzed in three rhesus macaques (KPed rhesus) with clear allografts that survived more than 6 months. MLR was done using peripheral blood mononuclear cells (PBMC). PBMCs from the recipient rhesus and normal rhesus were used as responder cells and PBMCs from ...
OBJECTIVES : To use SIVmac-infected Chinese-origin rhesus macaques (Ch Rh) to characterize the immunopathology of the long term non-progressor (LTNP) state. The key questions addressed were whether or not LTNP experience an early and rapid loss of mucosal CD4 T cells during the acute infection and the mechanisms by which they maintain the LTNP state. METHODS : Ch Rh were infected with SIVmac239. Polychromatic flow cytometry was used to analyze T lymphocyte subsets from blood, lymph nodes and gut tissues during SIV infection. Plasma viral loads were monitored by bDNA assay. Two LTNP were treated with anti-CD8 antibody to deplete CD8 cells in vivo. RESULTS : Thirty-one percent (5/16) of SIVmac239-infected ChRh having low viral loads for as long as 6 years were LTNP. Both LTNP and progressors had similar levels of gut memory CD4/CCR5 T cells (target cells) before infection and there was an early and profound depletion of target cells in both groups. LTNP were distinguished by gradual restoration of
Honing, H., Merchant, H., Háden, G.P., Prado, L. & Bartolo, R. (2012). Rhesus monkeys (Macaca mulatta) detect rhythmic groups in music, but not the beat. PLoS ONE, 7(12): e51369. doi: 10.1371/journal.pone.0051369 It was recently shown that rhythmic entrainment, long considered a human-specific mechanism, can be demonstrated in a selected group of bird species, and, somewhat surprisingly, not in more closely related species such as nonhuman primates. This observation supports the vocal learning hypothesis that suggests rhythmic entrainment to be a by-product of the vocal learning mechanisms that are shared by several bird and mammal species, including humans, but that are only weakly developed, or missing entirely, in nonhuman primates. To test this hypothesis we measured auditory event-related potentials (ERPs) in two rhesus monkeys (Macaca mulatta), probing a well-documented component in humans, the mismatch negativity (MMN) to study rhythmic expectation. We demonstrate for the first time in ...
Optimal perceptual decisions require sensory signals to be combined with prior information about stimulus probability. Although several theories propose that probabilistic information about stimulus occurrence is encoded in sensory cortex, evidence from neuronal recordings has not yet fully supported this view. We recorded activity from single neurons in inferior temporal cortex (IT) while monkeys performed a task that involved discriminating degraded images of faces and fruit. The relative probability of the cue being a face versus a fruit was manipulated by a latent variable that was not revealed to the monkeys and that changed unpredictably over the course of each recording session. In addition to responding to stimulus identity (face or fruit), population responses in IT encoded the long-term stimulus probability of whether a face or a fruit stimulus was more likely to occur. Face-responsive neurons showed reduced firing rates to expected faces, an effect consistent with expectation suppression,
...Key differences in immune system signaling and the production of speci...Following the identification of HIV (Human Immunodeficiency Virus) as ...Surprisingly the natural hosts for the AIDS viruses such as the mang...A team of scientists from Yerkes National Primate Research Center and ...,Why,some,primates,,but,not,humans,,can,live,with,immunodeficiency,viruses,and,not,progress,to,AIDS,biological,biology news articles,biology news today,latest biology news,current biology news,biology newsletters
Rhesus macaque monkeys infected with simian immunodeficiency virus (SIV) harbor immunoglobulin G (IgG) and SIV-specific antibodies and T cells in the foreskin of the penis, according to a study in the July 2012 Journal of ...
Cross-species transplant in rhesus macaques is step toward diabetes cure for humans Friday, 19 October 2007 With an eye on curing diabetes, scientists at Washington University School of Medicine in St. Louis have successfully transplanted embryonic pig pancreatic cells destined to produce insulin into diabetic macaque monkeys - all without the need for risky immune suppression drugs that prevent rejection. The transplanted cells, known as primordia, are in the earliest stages of developing into pancreatic tissues. Within several weeks of the transplants, the cells became engrafted, or established, within the three rhesus macaque monkeys that received them. The cells also released pig insulin in response to rising blood glucose levels, as would be expected in healthy animals and humans. "The approach reduced the animals need for insulin injections and has promise for curing diabetes in humans," says senior investigator Marc Hammerman, M.D., the Chromalloy Professor of Renal Diseases in Medicine. ...
Mark, L, Spiller, OB, Okroj, M, Chanas, S, Aitken, JA, Wong, SW, Damania, B, Blom, AM and Blackbourn, DJ (2007) Molecular characterization of the rhesus rhadinovirus (RRV) ORF4 gene and the RRV complement control protein it encodes ...
Methods: We evaluated 3 modalities of a 2-dose iPrEP regimen with Truvada in 6 male rhesus macaques by using an established rectal transmission model consisting of 14 weekly virus (simian HIV [SHIV]162p3,10 TCID50) exposures. Truvada at human equivalent dosing was delivered by oral gavage. Drug doses were given at different intervals relative to virus exposure: 2 groups of macaques received the 2 doses of Truvada over a 24-hour period, either 2 hours before and 22 hours after virus exposure (group I) or 22 hours before and 2 hours after exposure (group II). Group III received the first dose of Truvada 3 days before exposure and a second dose 2 hours after exposure. A fourth group of 6 macaques received 2 PEP doses 2 hours and 26 hours after exposure. Infection was monitored by serology and polymerase chain reaction (PCR) amplification of SHIV sequences from plasma and peripheral blood mononuclear cells (PBMC). The Cox proportional hazards model was used to estimate the risk of infection in ...
A post we made last week suggested a new vaccine can protect macaques against the monkey equivalent of HIV, however the vaccine using the common virus cytomegalovirus (CMV) as the vector or container of proteins from the simian immunodeficiency virus (SIV) protected none of a group of 24 rhesus macaques from infection. But in 13…
Oregon health and Science University is practicing the barbaric act of using primates to test largely preventable human conditions: OBESITY & DIABETES.. Shiva and her colony which are mostly Rhesus Macaques are fattened up being fed daily with fattening foods, allowed no exercise, caged and once obese enough, they test various drugs and procedures on them.. Dr Grove said: "Our research model is a sedentary lifestyle with calorically dense diets". Monkeys in this facility receive daily painful insulin shots to treat the human inflicted diabetes, and some develop clogged arteries. One monkey already died from a heart attack at a very young age. The unfortunate primate that is going through this suffers between months and years for human conditions that can largely be prevented by eating a healthy diet, which is obvious from this information. They had to fatten up the monkeys with unhealthy foods to be able to test these preventable diseases.. This doesnt stop there as some endure the painful ...
Anatomical description of the periprostatic nerves in the male rhesus monkey (Macaca mulatta). Ganzer R, Neuhaus J, Gratzke C, Blana A, Wieland WF, Stolzenburg JU. World J Urol. 2011 Jun;29(3):375-80. No mutations of FGFR3 in normal urothelium in the vicinity of urothelial carcinoma of the bladder harbouring activating FGFR3 mutations in patients with bladder cancer. Otto W, Denzinger S, Bertz S, Gaumann A, Wild PJ, Hartmann A, Stoehr R. Int J Cancer. 2009 Nov 1;125(9):2205-8. Mdm2-SNP309 polymorphism in prostate cancer: no evidence for association with increased risk or histopathological tumour characteristics. Stoehr R, Hitzenbichler F, Kneitz B, Hammerschmied CG, Burger M, Tannapfel A, Hartmann A. Br J Cancer. 2008 Jul 8;99(1):78-82. Topographical anatomy of periprostatic and capsular nerves: quantification and computerised planimetry. Ganzer R, Blana A, Gaumann A, Stolzenburg JU, Rabenalt R, Bach T, Wieland WF, Denzinger S. Eur Urol. 2008 Aug;54(2):353-61. Pax-5 protein expression in bladder ...
Bhaskar Chanda Stem Cell In this article, Sato and colleagues describe the generation of an immunodeficient nonhuman primate model. By optimizing ZFN and TALEN targeting of the IL2RG gene in marmoset fibroblasts and embryos, and using blastomere splitting as a proxy for rapid genome editing to reduce mosaicism, the authors generated founder animals with an immunodeficient phenotype similar to that of human patients with X-SCID.. from Cell Stem Cell http://ift.tt/29baMQ2 ...
Author: Asztalos, Bela F. et al.; Genre: Journal Article; Published in Print: 2010-08-15; Title: Circulating Nef Induces Dyslipidemia in Simian Immunodeficiency Virus-Infected Macaques by Suppressing Cholesterol Efflux
The Yerkes National Primate Research Center in Atlanta, Georgia, is one of seven national primate research centers funded by the National Institutes of Health. It is known for its biomedical and behavioral studies with nonhuman primates. Its 25-acre (10 ha) Main Station contains most of the centers biomedical research laboratories. The center also includes the 117-acre (47 ha) Yerkes Field Station near Lawrenceville, Georgia. The center was established in 1930 by Robert Yerkes, in Orange Park, Florida, associated then with Yale University. Yerkes was a pioneering primatologist who specialized in comparative psychology. In 1965, it relocated to its present location on the campus of Emory University. The Field Station houses 3,400 animals, specializes in behavioral studies of primate social groups, and is located 30 miles (48 km) northeast of Atlanta, on 117 acres (47 ha) of wooded land. The Living Links Center is a part of the Yerkes National Primate Research Center run by primatologist Frans De ...
Purpose : As reported previously, hemiretinal endodiathermy axotomy (HEA) of the inferior retinal nerve fiber bundle in non-human primates (NHPs) isolates the outer retina, resulting in nearly complete loss of axons in the lower half of the optic nerve without disrupting outer retinal anatomy, opsin regulation, retinal or choroidal blood flow. In the present study we used spectral domain optical coherence tomography (sdOCT) to characterize early post-HEA structural changes, to chart the time course of retinal ganglion cell (RGC) loss, to assess development of microcystoid macular degeneration (MMD) and to elucidate the utility of HEA in NHPs as a model for studying outer retinal injury, MMD and RGC degeneration.. Methods : Contiguous endodiathermy spots were placed along the inferior 180° adjacent to the optic nerve margin in the right eyes of 3 young adult rhesus monkeys (1 female, 2 male). A Heidelberg Spectralis HRA+OCT (Heidelberg Engineering) was used to collect macular volume, retinal ...
A highly conserved threonine near the C terminus of gp120 of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) was investigated for its contributions to envelope protein function and virion infectivity. When this highly conserved Thr residue was substituted with anything other than serine (the other amino acid that can accept O-glycosylation), the resulting virus was noninfectious. We found that this Thr was critical for the association of gp120 with the virion and that amino acid substitution increased the amount of dissociated gp120 in the cell culture supernatant. When HIV virions were generated in cells overexpressing polypeptide N-acetylgalactosaminyltransferase 1 (GalNAcT1), viral infectivity was increased 2.5-fold compared to that of virus produced in wild-type HEK293T cells; infectivity was increased 8-fold when the Thr499Ser mutant was used. These infectivity enhancements were not observed when GalNAcT3 was used. Using HEK293T knockout cell lines totally devoid ...
Abstract To learn more about the course of Babesia microti infections in primates, six Macaca mulatta monkeys with blood-induced B. microti infections were followed for 270 days with regular thick blood smears. Three of the monkeys experienced from 1-3 recurrences of parasitemia defined here as ⩾200 organisms/mm3 blood. Following splenectomy on day 297, parasitemia recurred in all animals, reaching levels of 1.9 × 105 to 2.7 × 106 organisms/mm3, and was associated with a moderately severe hemolytic anemia. These findings suggest that similar recurrences of parasitemia may occur in human cases, and that splenectomy may present a risk to persons with a past history of B. microti infection.
The Wolfgang Köhler Primate Research Center (Pongoland) is a project of the Max Planck Institute for Evolutionary Anthropology. It is operated in collaboration with the Leipzig Zoo. Research focuses on the behavior and cognition of the four species of great ape: chimpanzees (Pan troglodytes), gorillas (Gorilla gorilla), Organgutans (Pongo pygmaeus), and bonobos (Pan paniscus). There is a special focus on the ontogeny of chimpanzee cognition. Researchers and students from the University of Leipzig, and other universities around the world, conduct their research projects at the center guided by the personnel of the Center ...
El macaco de Sri Lanka (Macaca sinica) es una especie de primate catarrino de la familia Cercopithecidae.[2]​ Es endémico de Sri Lanka.[2]​ Se reconocen tres subespecies:[1]​ Macaca sinica aurifrons Macaca sinica opisthomelas Macaca sinica sinica Se encuentra en peligro de extinción, principalmente por la pérdida de su hábitat natural. Dittus, W., Watson, A. & Molur, S. (2008). «Macaca sinica». Lista Roja de especies amenazadas de la UICN 2008 (en inglés). Consultado el 8 de agosto de 2011. Groves, Colin (2005). Wilson, D. E.; Reeder, D. M, eds. Mammal Species of the World (3ª edición). Baltimore: Johns Hopkins University Press. p. 164. ISBN 0-8018-8221-4. Wikispecies tiene un artículo sobre Macaca sinica. Wikispecies Wikimedia Commons alberga contenido multimedia sobre Macaca sinica. Commons ARKive - images and movies of the toque macaque (Macaca sinica) BBC - Science & Nature - Animals - Toque macaque Wolfgang Dittus - A Toque Macaque ...
Purpose: : To evaluate the integrity of the cortical networks, using functional Magnetic Resonance Imaging (fMRI), that underlie saccadic and smooth pursuit eye movements in patients with age-related macular degeneration (AMD). Methods: : Five patients with AMD (range 55 - 83 years of age, M=69.8), recruited from a reading rehabilitation program, completed two eye movement tasks while fMRI data were acquired. The patients visual acuities ranged from 20/76 to 20/360 in their better eye. Eye movement was monitored during scanning to insure task performance. Patients first completed a visually guided saccade (VGS) task which required alternating periods of central fixation with 3° eye movements along the horizontal plane. Patients then completed a smooth pursuit (SMP) task which required patients to follow a dot along the horizontal plane (alternating with fixation). FMRI data were acquired on a 3.0-Tesla whole body scanner (GEMS, Waukesha, WI) using serial gradient echo, echo-planar imaging. ...

Macaca mulatta / Invasive Species of JapanMacaca mulatta / Invasive Species of Japan

Macaca mulatta × Macaca fuscata is Invasive alien species (Invasive Species Act). All the species of Macaca (except for M. ... Native organism(s) affected: Native macaque Macaca fuscata, vegetation, crops. Regulation in Japan. Import, transport and ... cyclopis, M. fascicularis, M. mulatta, and M. fuscata) are designated as Uncategorized Alien Species by the Invasive Alien ...
more infohttps://www.nies.go.jp/biodiversity/invasive/DB/detail/10390e.html

Uncharacterized protein - Macaca mulatta (Rhesus macaque)Uncharacterized protein - Macaca mulatta (Rhesus macaque)

Macaca mulatta (Rhesus macaque)Imported. Automatic assertion inferred from database entriesi ... tr,F7EQL6,F7EQL6_MACMU Uncharacterized protein OS=Macaca mulatta OX=9544 PE=4 SV=2 ... Macaca fascicularis brain cDNA clone: QmoA-11376, similar to human 1-acylglycerol-3-phosphate O-acyltransferase 3 (AGPAT3), ... Macaca fascicularis brain cDNA clone: QmoA-11376, similar to human 1-acylglycerol-3-phosphate O-acyltransferase 3 (AGPAT3), ...
more infohttps://www.uniprot.org/uniprot/F7EQL6

TSA: Macaca mulatta Mamu 514003 mRNA sequence - Nucleotide - NCBITSA: Macaca mulatta Mamu 514003 mRNA sequence - Nucleotide - NCBI

TSA: Macaca mulatta Mamu_514003 mRNA sequence TSA: Macaca mulatta Mamu_514003 mRNA sequence. gi,380811233,gnl,bpid:PRJNA77627, ...
more infohttps://www.ncbi.nlm.nih.gov/nucleotide/380811233

TSA: Macaca mulatta Mamu 453562 mRNA sequence - Nucleotide - NCBITSA: Macaca mulatta Mamu 453562 mRNA sequence - Nucleotide - NCBI

TSA: Macaca mulatta Mamu_453562 mRNA sequence TSA: Macaca mulatta Mamu_453562 mRNA sequence. gi,387462168,gnl,bpid:PRJNA77627, ...
more infohttps://www.ncbi.nlm.nih.gov/nucleotide/387462168

Macaca mulatta - Wikipedia, a enciclopedia libreMacaca mulatta - Wikipedia, a enciclopedia libre

Wikispecies posúe unha páxina sobre: Macaca mulatta. Ligazóns externas[editar , editar a fonte]. *Primate Info Net: Macaca ... "Macaca mulatta". Lista Vermella de especies ameazadas. Versión 2016.2 (en inglés). Unión Internacional para a Conservación da ... Macaca mulatta, xeralmente chamado macaco rhesus (ou macaco -ou mono- Rhesus, resus ou reso), é unha especie de mono do Vello ... Taxonomic revision and distribution of subspecies of Rhesus Monkey (Macaca mulatta) in China. Zoological Research, 1991-03 ...
more infohttps://gl.wikipedia.org/wiki/Macaca_mulatta

Browsing  by Subject Macaca mulattaBrowsing by Subject "Macaca mulatta"

The Prophylactic and radical curative activity of RC-12 against Plasmodium cynomolgi in Macaca mulatta / by Thomas M. Sodeman ...
more infohttps://extranet.who.int/iris/restricted/browse?authority=Macaca+mulatta&type=mesh

Geneimprint : Macaca mulatta MKRN3Geneimprint : Macaca mulatta MKRN3

Macaca mulatta. MKRN3. 7 Imprinted. Paternal. Homo sapiens. MKRN3. D15S9, RNF63, ZFP127, ZNF127, MGC88288 15q11-q13 Imprinted. ...
more infohttp://www.geneimprint.com/site/genes/Macaca_mulatta_MKRN3

Geneimprint : Macaca mulatta IGF2RGeneimprint : Macaca mulatta IGF2R

Macaca mulatta: IGF2R. Insulin-like growth factor 2 receptor. Killian et al. Mol Cell 5: 707-716, 2000 Cheong et al. Genome Res ...
more infohttp://www.geneimprint.com/site/genes/Macaca_mulatta_IGF2R

Primate Factsheets: Rhesus macaque (Macaca mulatta) ReferencesPrimate Factsheets: Rhesus macaque (Macaca mulatta) References

Macaca mulatta. Taxonomy, Morphology, & Ecology , Behavior , Conservation , ,References, , Links , AV. The following references ... Rhesus monkeys ( Macaca mulatta ) in the Taihang Mountains , Jiyuan County , Henan , China . Int J Primatol 14(4): 607-21. ... Geophagy as a therapeutic mediator of endoparasitism in a free-ranging group of rhesus macaques (Macaca mulatta). Am J Primatol ... To find current references for Macaca mulatta, search PrimateLit. REFERENCES. Anonymous. 2005. Primate center discoveries. ...
more infohttp://pin.primate.wisc.edu/factsheets/entry/rhesus_macaque/ref

CLDN4 - Claudin - Macaca mulatta (Rhesus macaque) - CLDN4 gene & proteinCLDN4 - Claudin - Macaca mulatta (Rhesus macaque) - CLDN4 gene & protein

Macaca mulatta (Rhesus macaque)Imported. Automatic assertion inferred from database entriesi ... tr,F6YR27,F6YR27_MACMU Claudin OS=Macaca mulatta OX=9544 GN=CLDN4 PE=2 SV=1 ...
more infohttps://www.uniprot.org/uniprot/F6YR27

KEGG PATHWAY: Influenza A - Macaca mulatta (rhesus monkey)KEGG PATHWAY: Influenza A - Macaca mulatta (rhesus monkey)

Influenza A - Macaca mulatta (rhesus monkey) [ Pathway menu , Organism menu , Pathway entry , Download KGML , Show description ...
more infohttp://www.genome.jp/kegg-bin/show_pathway?mcc05164+698729

KEGG PATHWAY: Cell cycle - Macaca mulatta (rhesus monkey)KEGG PATHWAY: Cell cycle - Macaca mulatta (rhesus monkey)

Cell cycle - Macaca mulatta (rhesus monkey) [ Pathway menu , Organism menu , Pathway entry , Download KGML , Show description ...
more infohttps://www.genome.jp/kegg-bin/show_pathway?mcc04110+699269

CONCEPT Macaca mulattaCONCEPT Macaca mulatta

Macaca mulatta.,NCI: A pale brown macaque (Macaca mulatta) native to India, China, and other parts of Asia; often used in ... A medium-sized diurnal primate, the Macaca mulatta has a diet of plant material and insects that it can store in pouches in its ... Macaca mulatta Source:http://linkedlifedata.com/resource/umls/id/C0024400 CSP: species of the genus MACACA inhabiting India, ... A species of the genus MACACA inhabiting India, China, and other parts of Asia. The species is used extensively in biomedical ...
more infohttp://linkedlifedata.com/resource?uri=http://linkedlifedata.com/resource/umls/id/C0024400

What does macaca mulatta mean?What does macaca mulatta mean?

Meaning of macaca mulatta. What does macaca mulatta mean? Information and translations of macaca mulatta in the most ... Definition of macaca mulatta in the Definitions.net dictionary. ... Search for macaca mulatta on Amazon. *Search for macaca mulatta ... What does macaca mulatta mean?. Definitions for macaca mulatta. Here are all the possible meanings and translations of the word ... Get even more translations for macaca mulatta ». Translation. Find a translation for the macaca mulatta definition in other ...
more infohttps://www.definitions.net/definition/macaca%20mulatta

Paternal kinship among adult female rhesus macaques (Macaca mulatta)Paternal kinship among adult female rhesus macaques (Macaca mulatta)

Macaca mulatta) living on the island of Cayo Santiago. The main findings can be summarised as follows: Firstly, in order to ... Macaca mulatta) auf der Insel Cayo Santiago. Die wichtigsten Resultate können folgendermaßen zusammengefaßt werden: Erstens, ...
more infohttps://edoc.hu-berlin.de/handle/18452/15482?C=M

Paternal kinship among adult female rhesus macaques (Macaca mulatta)Paternal kinship among adult female rhesus macaques (Macaca mulatta)

Macaca mulatta) living on the island of Cayo Santiago. The main findings can be summarised as follows: Firstly, in order to ... Macaca mulatta) auf der Insel Cayo Santiago. Die wichtigsten Resultate können folgendermaßen zusammengefaßt werden: Erstens, ...
more infohttps://edoc.hu-berlin.de/handle/18452/15482

Macaca mulatta Mamu-B 01 antigen
     Summary Report | CureHunterMacaca mulatta Mamu-B 01 antigen Summary Report | CureHunter

Macaca mulatta Mamu-B 01 antigen: a MHC class I B locus allele-restricted similan immunodeficiency virus envelope CTL epitope ... Macaca mulatta Mamu-B 01 antigen. Subscribe to New Research on Macaca mulatta Mamu-B 01 antigen ... Mamu-B 01 antigen, Macaca mulatta; Mamu-B 01 protein, Macaca mulatta ...
more infohttp://www.curehunter.com/public/keywordSummaryC092249-Macaca-mulatta-Mamu-B-01-antigen.do

Familial Circadian Rhythm Disorder in the Diurnal Primate, Macaca mulattaFamilial Circadian Rhythm Disorder in the Diurnal Primate, Macaca mulatta

In view of the inverse temporal relationship of central clock activity to physiological or behavioral outputs in diurnal and nocturnal species, understanding the mechanisms and physiological consequences of circadian disorders in humans would benefit from studies in a diurnal animal model, phylogenetically close to humans. Here we report the discovery of the first intrinsic circadian disorder in a family of diurnal non-human primates, the rhesus monkey. The disorder is characterized by a combination of delayed sleep phase, relative to light-dark cycle, mutual desynchrony of intrinsic rhythms of activity, food intake and cognitive performance, enhanced nighttime feeding or, in the extreme case, intrinsic asynchrony. The phenotype is associated with normal length of intrinsic circadian period and requires an intact central clock, as demonstrated by an SCN lesion. Entrainment to different photoperiods or melatonin administration does not eliminate internal desynchrony, though melatonin can temporarily
more infohttp://journals.plos.org/plosone/article?id=10.1371/journal.pone.0033327

Vaccination of Rhesus monkeys (‎Macaca mulatta)‎ against Plasmodium knowlesi by the use of nonviable antigenVaccination of Rhesus monkeys (‎Macaca mulatta)‎ against Plasmodium knowlesi by the use of nonviable antigen

Schenkel, Robert H., Simpson, Gary L. & Silverman, Paul H. (‎1973)‎. Vaccination of Rhesus monkeys (‎Macaca mulatta)‎ against ... Vaccination of Rhesus monkeys (‎Macaca mulatta)‎ against Plasmodium knowlesi by the use of nonviable antigen. ...
more infohttp://apps.who.int/iris/handle/10665/263849

KATNB1 gene cDNA ORF clone, Macaca mulatta(Rhesus monkey) - GenScriptKATNB1 gene cDNA ORF clone, Macaca mulatta(Rhesus monkey) - GenScript

Macaca mulatta(Rhesus monkey). Definition Macaca mulatta katanin p80 (WD repeat containing) subunit B 1 (KATNB1), transcript ... Macaca mulatta(Rhesus monkey). Definition Macaca mulatta katanin p80 (WD repeat containing) subunit B 1 (KATNB1), transcript ... Macaca mulatta(Rhesus monkey). Definition Macaca mulatta katanin p80 (WD repeat containing) subunit B 1 (KATNB1), transcript ... KATNB1 ( XM_015126273.1 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -, XP_014981759.1 Macaca mulatta katanin p80 (WD repeat ...
more infohttps://www.genscript.com/gene/other/711862/katnb1.html

Elasticity and stress relaxation of rhesus monkey (Macaca mulatta) vocal folds | Journal of Experimental BiologyElasticity and stress relaxation of rhesus monkey (Macaca mulatta) vocal folds | Journal of Experimental Biology

1962). Vocal communication by the rhesus monkey Macaca mulatta, Proc. R. Soc. Lond. B. Biol. Sci. 138, 279-294. ... Elasticity and stress relaxation of rhesus monkey (Macaca mulatta) vocal folds Message Subject (Your Name) has sent you a ... 1974). Cortical motor representation of the laryngeal muscles in Macaca mulatta. Brain Res. 73, 229-240. ... In this study, I tested if stress-strain and stress-relaxation behavior of rhesus monkey (Macaca mulatta) vocal folds allows ...
more infohttp://jeb.biologists.org/content/213/17/2924

CIL:48059, Macaca mulatta, kidney glomerular epithelial cell. CIL. DatasetCIL:48059, Macaca mulatta, kidney glomerular epithelial cell. CIL. Dataset

Macaca mulatta Cell Type. kidney glomerular epithelial cell Cell Line. Cortex of kidney ... Marian Miller (2015) CIL:48059, Macaca mulatta, kidney glomerular epithelial cell. CIL. Dataset. https://doi.org/doi:10.7295/ ...
more infohttp://ccdb.ucsd.edu/images/48059

Alzheimers Abeta vaccination of rhesus monkeys (Macaca mulatta).  - Zurich Open Repository and ArchiveAlzheimer's Abeta vaccination of rhesus monkeys (Macaca mulatta). - Zurich Open Repository and Archive

Macaca mulatta) were vaccinated with aggregated Abeta(1-42). Immunized monkeys developed anti-Abeta titers exceeding 1:1000, ... Macaca mulatta) were vaccinated with aggregated Abeta(1-42). Immunized monkeys developed anti-Abeta titers exceeding 1:1000, ... Macaca mulatta). Mechanisms of Ageing and Development, 125(2):149-151. ...
more infohttp://www.zora.uzh.ch/id/eprint/1941/

Estradiol increases somatomedin-C concentrations in adolescent rhesus macaques (Macaca
      mulatta).Estradiol increases somatomedin-C concentrations in adolescent rhesus macaques (Macaca mulatta).

Estradiol increases somatomedin-C concentrations in adolescent rhesus macaques (Macaca mulatta).. код для вставки. код для ... Walker, M.L.; Gordon, T.P.; Wilson, M.E. Reproductive performance in capture acclimated female rhesus monkesy (Macaca mulatta ... Van Wagenen, G.; Catchpole, H.R. Physical growth of the rhesus monkey (Macaca mulatta). AMERICAN JOURNAL OF PHYSICAL ... Macaca mulatta. ACTA ENDOCRINOLOGICA (COPEH) 102:190195, 1983. Copeland, K.C.; Eichberg, J.W.; Parker, Jr., C.R.: Bartke. A. ...
more infohttps://www.docme.ru/doc/1946107/estradiol-increases-somatomedin-c-concentrations-in-adole..

Variation in Rhesus Macaque (Macaca mulatta) Vocalizations: Social and by Emma A. McNamara"Variation in Rhesus Macaque (Macaca mulatta) Vocalizations: Social and" by Emma A. McNamara

Macaca mulatta) are the most widely studied nonhuman primate. While some work has been done on both vocal communication and the ... Rhesus macaques (Macaca mulatta) are the most widely studied nonhuman primate. While some work has been done on both vocal ...
more infohttps://repository.upenn.edu/anthro_seniortheses/180/
  • A medium-sized diurnal primate, the Macaca mulatta has a diet of plant material and insects that it can store in pouches in its mouth. (linkedlifedata.com)
  • American Journal of Primatology 11:53-62 (1986) Estradiol Increases Somatomedin-C Concentrations in Adolescent Rhesus Macaques (Macaca mulatta) ERIN L. OSTERUD, SUZETTE LACKEY, AND MARK E. WILSON Yerkes Regional Primate Research Center ofEmory University, Field Station, Lawrenceuille, Georgia Estradiol (E2) may enhance somatomedin-C(Sm-C)secretion during puberty in female rhesus monkeys. (docme.ru)
  • Rhesus macaques ( Macaca mulatta ) are the most widely studied nonhuman primate. (upenn.edu)
  • The socioendocrinology of adolescent development in male rhesus monkeys ( Macaca mulatta ). (wisc.edu)
  • To examine the mechanisms and consequences of anti-Abeta-antibody formation in a species more closely related to humans, rhesus monkeys (Macaca mulatta) were vaccinated with aggregated Abeta(1-42). (uzh.ch)
  • In this study, I tested if stress-strain and stress-relaxation behavior of rhesus monkey ( Macaca mulatta ) vocal folds allows the prediction of a species' natural fundamental frequency range across its entire vocal repertoire as well as of frequency contours within a single call type. (biologists.org)
  • To evaluate the role of female skin color in the context of sexual signaling further, we investigated whether changes in sexual skin color contain information about the timing of the fertile phase in rhesus macaques ( Macaca mulatta ), a species in which adult females do not develop sexual swellings, but do express visually detectable changes in the skin color of the face and hindquarters. (springer.com)
  • Os límites de distribución sur e norte do M. mulatta e do M. radiata , actualmente corren paralelamente un doutro na parte oeste da India, están separados por un gran espazo no centro e converxen na costa leste da península para formar unha zona de distribución solapada. (wikipedia.org)
  • Hoxe, esa poboación coñécese como macaco rhesus da India, M. m. mulatta , que inclúe os morfoloxicamene similares M. rhesus villosus , descrito por True en 1894, de Caxemira , e M. m. mcmahoni , descrito por Pocock en 1932, de Kootai, Paquistán . (wikipedia.org)
  • Macaca mulatta katanin p80 (WD repeat containing) subunit B 1 (KATNB1), transcript variant X1, mRNA. (genscript.com)
  • The biology of light infections of Schistosoma mansoni and their immunogenic effects were studied in seven Macaca mulatta by means of routine egg counts, worm numbers and cellular reactions against schistosomula in the lungs. (ajtmh.org)
  • Macaca mulatta , xeralmente chamado macaco rhesus (ou macaco -ou mono- Rhesus, resus ou reso), é unha especie de mono do Vello Mundo que vive en parte de Asia. (wikipedia.org)
  • A four-year study of the association between male dominance rank, residency status, and reproductive activity in rhesus macaques ( Macaca mulatta ). (wisc.edu)
  • CIL:48059, Macaca mulatta, kidney glomerular epithelial cell. (ucsd.edu)
  • Freeze fracture images of synaptic junctions in the retina of Macaca mulatta. (ucsd.edu)
  • Geophagy as a therapeutic mediator of endoparasitism in a free-ranging group of rhesus macaques ( Macaca mulatta ). (wisc.edu)
  • After leaving the group, Chinchilla formed a new band, Macaca Mulata, with former members of London Punk band, Rhesus. (wikipedia.org)