Hematologic diseases and diseases of the lymphatic system collectively. Hemic diseases include disorders involving the formed elements (e.g., ERYTHROCYTE AGGREGATION, INTRAVASCULAR) and chemical components (e.g., BLOOD PROTEIN DISORDERS); lymphatic diseases include disorders relating to lymph, lymph nodes, and lymphocytes.
Diseases of LYMPH; LYMPH NODES; or LYMPHATIC VESSELS.
Tubular vessels that are involved in the transport of LYMPH and LYMPHOCYTES.
A system of organs and tissues that process and transport immune cells and LYMPH.
Unbroken cellular lining (intima) of the lymph vessels (e.g., the high endothelial lymphatic venules). It is more permeable than vascular endothelium, lacking selective absorption and functioning mainly to remove plasma proteins that have filtered through the capillaries into the tissue spaces.
The formation of LYMPHATIC VESSELS.

Ki-1 (CD30)-positive anaplastic large cell lymphoma, sarcomatoid variant accompanied by spontaneously regressing lymphadenopathy. (1/851)

Although it has been reported that primary Ki-1 (CD30)-positive anaplastic large cell lymphoma (ALCL) of the skin may undergo spontaneous regression, it is rare for ALCL without cutaneous involvement to have spontaneously regressing lymphadenopathy. We report a case of sarcomatoid variant of ALCL accompanied by spontaneously regressing lymphadenopathy. The patient had gastric and pulmonary involvement of ALCL in addition to systemic lymphadenopathy, but with no cutaneous involvement. The lymphadenopathy spontaneously improved gradually during a period of one month without any treatment. At the same time, multiple small nodules in both lung fields decreased on chest computed tomography and multiple elevated gastric tumors with dimples were endoscopically recognized to have improved. He has since been treated with combination chemotherapy because of recurrence of the lymphadenopathy.  (+info)

Angiogenesis extent and macrophage density increase simultaneously with pathological progression in B-cell non-Hodgkin's lymphomas. (2/851)

Node biopsies of 30 benign lymphadenopathies and 71 B-cell non-Hodgkin's lymphomas (B-NHLs) were investigated for microvessel and macrophage counts using immunohistochemistry and morphometric analysis. Both counts were significantly higher in B-NHL. Moreover, when these were grouped into low-grade and high-grade lymphomas, according to the Kiel classification and Working Formulation (WF), statistically significant higher counts were found in the high-grade tumours. Immunohistochemistry and electron microscopy revealed a close spatial association between microvessels and macrophages. Overall, the results suggest that, in analogy to what has already been shown in solid tumours, angiogenesis occurring in B-NHLs increases with tumour progression, and that macrophages promote the induction of angiogenesis via the release of their angiogenic factors.  (+info)

Adrenergic innervation in reactive human lymph nodes. (3/851)

Several experimental models have demonstrated that the central nervous system is functionally linked to the immune system by means of the autonomic nervous system. Samples of 36 lymph nodes of patients whose ages ranged from 16 to 69 y were studied. In order to demonstrate the existence and distribution of sympathetic nerve fibres, a polyclonal antibody antityrosine hydroxylase (TH), with the streptavidin-biotin system of detection, was used. TH-positive nerve fibres appeared in all reactive patterns of the lymph nodes studied. Thin nerve fascicles ramified at the hilar region and also in the connective tissue septae. Adventitial adrenergic nerve fibres were found following afferent, and to a lesser extent, efferent blood vessels. Another source of incoming nerve fibres was found at capsular level, accompanying blood vessels. On the arterial side, the innervation ceased before reaching the follicular arterioles. Our demonstration of innervation in postcapillary venules could support a regulatory role of adrenergic neurotransmitters in lymphocyte traffic. Occasional nerve fibres were also seen in T areas among parenchymatous cells. These findings confirm the existence of sympathetic innervation in human lymph nodes, and provide indirect evidence that the psychoneuroimmune axis could also exist in humans.  (+info)

The prevalence and CT appearance of the levator claviculae muscle: a normal variant not to be mistaken for an abnormality. (4/851)

BACKGROUND AND PURPOSE: The levator claviculae muscle is an infrequently recognized variant in humans, occurring in 2% to 3% of the population, and has rarely been reported in the radiologic or anatomic literature. The importance of this muscle to radiologists is in distinguishing it from an abnormality; most commonly, cervical adenopathy. After discovering this muscle on the CT scans of two patients during routine clinical examinations, we conducted a study to determine the prevalence and appearance of the muscle on CT studies. METHODS: We evaluated 300 CT scans that adequately depicted the expected location of the muscle. The most superior level in which the muscle could be identified and the apparent location of insertion on the clavicle were recorded for all subjects in whom the muscle was detected. RESULTS: Seven levator claviculae muscles were identified in six subjects (2%). It was bilateral in one, on the left in four, and on the right in one. It was identified up to the level of the transverse process of C3 in all cases. The insertion was the middle third of the clavicle for two muscles and the lateral third of the clavicle for the remaining five muscles. CONCLUSION: Because the levator claviculae muscle will most likely be encountered during a radiologist's career, it is important to recognize this muscle as a variant and not as an abnormality.  (+info)

Primary Sjogren's syndrome in the North East of England: a long-term follow-up study. (5/851)

OBJECTIVE: Although primary Sjogren's syndrome is often a benign condition, characterized by lymphocytic infiltration of salivary and lacrimal glands, some patients develop systemic features. We have previously found that anti-Ro antibodies identified patients with more systemic disease, with increased incidence of parotid swelling, lymphadenopathy and lymphoma. METHODS: We have followed up a cohort of 100 patients over 10 yr, to establish whether the phenotypic expression of disease changed, and whether the different autoantibody patterns expressed at presentation could be used to predict outcome. RESULTS: While seronegative patients (ANA, RF, Ro and La negative) remained polysymptomatic, they did not develop systemic complications or serological changes. Thirty-nine per cent of ANA- or RF-positive patients who were negative for Ro and La were given revised diagnoses over the follow-up period, including rheumatoid arthritis, systemic lupus erythematosus, mixed connective tissue disease and scleroderma. Parotid swelling and lymphadenopathy were more common in Ro/La-positive patients, where the relative risk of developing non-Hodgkin's lymphoma was 49.7. CONCLUSION: Both HLA B8 and DR3 were present in 79% of Ro/La-positive patients, but were found together in only 4% of seronegative patients, supporting the view that these clinical subgroups of primary Sjogren's syndrome are both serologically and immunogenetically distinct. Patients who are initially autoantibody (including Ro and La) negative do not evolve into 'systemic' Sjogren's syndrome or other connective tissue diseases.  (+info)

A central role for alpha beta T cells in the pathogenesis of murine lupus. (6/851)

We have previously shown that female transgenic mice expressing IFN-gamma in the epidermis, under the control of the involucrin promoter, develop inflammatory skin disease and a form of murine lupus. To investigate the pathogenesis of this syndrome, we generated female IFN-gamma transgenic mice congenitally deficient in either alpha beta or gamma delta T cells. TCR delta-/- transgenics continued to produce antinuclear autoantibodies and to develop severe kidney lesions. In contrast, TCR beta-/- IFN-gamma transgenic mice failed to produce antinucleosome, anti-dsDNA, or antihistone autoantibodies, and kidney disease was abolished. Both alpha beta- and gamma delta-deficient transgenics continued to develop IFN-gamma-associated skin disease, lymphadenopathy, and splenomegaly. The data show that the autoantibody-mediated pathology of murine lupus in IFN-gamma transgenic mice is completely alpha beta T cell dependent and that gamma delta T cells cannot drive autoantibody production. These results imply that production of antinuclear autoantibodies in IFN-gamma transgenic animals is Ag driven, and we identified clusters of apoptotic cells in the epidermis of the mice as a possible source of self Ags. Our findings emphasize the relevance of this murine lupus model to the human disease.  (+info)

Cladribine activity in adult langerhans-cell histiocytosis. (7/851)

Langerhans-cell histiocytosis (LCH) results from the accumulation of tissue histiocytes derived from the same progenitor cells as monocytes. Because cladribine is potently toxic to monocytes, we conducted a phase II trial of cladribine. Cladribine was administered to 13 LCH patients at 0.14 mg/kg per day by 2-hour intravenous infusion for 5 consecutive days, every 4 weeks for a maximum of six courses. Median age was 42 years (range, 19 to 72) and median pretreatment disease duration was 99 months (range, 6 to 252). One patient was untreated, one had received prior prednisone only, one prior radiation only, six prior radiation and chemotherapy, and four prior surgery, radiation, and chemotherapy. Seven patients had cutaneous involvement, six multifocal osseous, six pulmonary, two each with soft tissue and nodal involvement, and four had diabetes insipidus. Of 13 patients, 12 were evaluable for response and all for toxicity. After a median of three courses (range, 1 to 6), seven (58%) patients achieved complete responses (two pathologic and five clinical) and two (17%) patients achieved partial responses; overall response rate, 75%. Median response follow-up duration was 33 months (range, 1 to 65). Seven patients experienced grade 3 to 4 neutropenia. Only one patient had a documented infection, dermatomal herpes zoster. At a median follow-up of 42 months (range, 5 to 76), 12 patients remain alive and one patient has died. Thus, cladribine has major activity in adult LCH and warrants further investigation in both pediatric and adult LCH as a single agent and in combination with other drugs.  (+info)

Lymphatic and haematopoietic cancer mortality in a population attending school adjacent to styrene-butadiene facilities, 1963-1993. (8/851)

STUDY OBJECTIVE: To evaluate the risk of mortality from lymphatic and haematopoietic cancers and other causes among students. DESIGN: The study used school records, yearbooks, and Texas Department of Health records for the school years 1963-64 to 1992-93 to construct a cohort of 15,403 students. Three mortality databases were searched to identify deaths, and mortality rates in the cohort were compared with mortality rates from the United States and Texas. Computed standardised mortality ratios and 95% confidence intervals were used. SETTING: Eastern Texas high school adjacent to facilities that have been producing synthetic styrene-butadiene since 1943. MAIN RESULTS: 338 deaths were identified. The all causes standardised mortality ratio was 0.84 (95% confidence intervals 0.74, 0.95) for men and 0.89 (0.73, 1.09) for women. The standardised mortality ratio for all lymphatic and haematopoietic cancers was 1.64 (95% confidence intervals 0.85, 2.87) for men and 0.47 (0.06, 1.70) for women. The slight male excess in lymphatic and haematopoietic cancers was stronger among men who attended school for two years or less. CONCLUSIONS: The overall mortality from lymphatic and haematopoietic cancer among the students was little different from that of the United States as a whole. A moderate excess for men, predominantly among the shorter-term students, was offset by a deficit among women. These variations are compatible with random fluctuations; the overall pattern is not indicative of an effect of environmental exposure sustained while attending the high school.  (+info)

Hemic diseases typically refer to conditions that affect the blood, bone marrow, or lymphatic system. Here are some examples:

1. Hematologic disorders: These are diseases related to the blood and include anemia (deficiency of red blood cells), leukemia (cancer of white blood cells), hemophilia (a genetic disorder that affects the blood's ability to clot), and thalassemia (a genetic disorder affecting red blood cell production).
2. Bone marrow disorders: These are conditions that affect the bone marrow, which is the spongy tissue inside bones where blood cells are produced. Examples include aplastic anemia (where the bone marrow doesn't produce enough new cells), myelodysplastic syndromes (conditions where the bone marrow produces abnormal cells), and leukemia.
3. Lymphatic disorders: These are conditions that affect the lymphatic system, which is a network of tissues and organs that help rid the body of waste and toxins. Examples include lymphoma (cancer of the lymphatic system), Hodgkin's disease, and non-Hodgkin's lymphoma.

It's important to note that this is not an exhaustive list, and there are many other hemic and lymphatic diseases. If you have concerns about any symptoms or conditions, it's best to consult with a healthcare professional for accurate information and treatment options.

Lymphatic diseases refer to a group of conditions that affect the lymphatic system, which is an important part of the immune and circulatory systems. The lymphatic system consists of a network of vessels, organs, and tissues that help to transport lymph fluid throughout the body, fight infection, and remove waste products.

Lymphatic diseases can be caused by various factors, including genetics, infections, cancer, and autoimmune disorders. Some common types of lymphatic diseases include:

1. Lymphedema: A condition that causes swelling in the arms or legs due to a blockage or damage in the lymphatic vessels.
2. Lymphoma: A type of cancer that affects the lymphatic system, including Hodgkin's and non-Hodgkin's lymphoma.
3. Infections: Certain bacterial and viral infections can affect the lymphatic system, such as tuberculosis, cat-scratch disease, and HIV/AIDS.
4. Autoimmune disorders: Conditions such as rheumatoid arthritis, lupus, and scleroderma can cause inflammation and damage to the lymphatic system.
5. Congenital abnormalities: Some people are born with abnormalities in their lymphatic system, such as malformations or missing lymph nodes.

Symptoms of lymphatic diseases may vary depending on the specific condition and its severity. Treatment options may include medication, physical therapy, surgery, or radiation therapy. It is important to seek medical attention if you experience symptoms of a lymphatic disease, as early diagnosis and treatment can improve outcomes.

Lymphatic vessels are thin-walled, valved structures that collect and transport lymph, a fluid derived from the interstitial fluid surrounding the cells, throughout the lymphatic system. They play a crucial role in immune function and maintaining fluid balance in the body. The primary function of lymphatic vessels is to return excess interstitial fluid, proteins, waste products, and immune cells to the bloodstream via the subclavian veins near the heart.

There are two types of lymphatic vessels:

1. Lymphatic capillaries: These are the smallest lymphatic vessels, found in most body tissues except for the central nervous system (CNS). They have blind ends and are highly permeable to allow the entry of interstitial fluid, proteins, and other large molecules.
2. Larger lymphatic vessels: These include precollecting vessels, collecting vessels, and lymphatic trunks. Precollecting vessels have valves that prevent backflow of lymph and merge to form larger collecting vessels. Collecting vessels contain smooth muscle in their walls, which helps to propel the lymph forward. They also have valves at regular intervals to ensure unidirectional flow towards the heart. Lymphatic trunks are large vessels that collect lymph from various regions of the body and eventually drain into the two main lymphatic ducts: the thoracic duct and the right lymphatic duct.

Overall, lymphatic vessels play a vital role in maintaining fluid balance, immune surveillance, and waste removal in the human body.

The lymphatic system is a complex network of organs, tissues, vessels, and cells that work together to defend the body against infectious diseases and also play a crucial role in the immune system. It is made up of:

1. Lymphoid Organs: These include the spleen, thymus, lymph nodes, tonsils, adenoids, and Peyer's patches (in the intestines). They produce and mature immune cells.

2. Lymphatic Vessels: These are thin tubes that carry clear fluid called lymph towards the heart.

3. Lymph: This is a clear-to-white fluid that contains white blood cells, mainly lymphocytes, which help fight infections.

4. Other tissues and cells: These include bone marrow where immune cells are produced, and lymphocytes (T cells and B cells) which are types of white blood cells that help protect the body from infection and disease.

The primary function of the lymphatic system is to transport lymph throughout the body, collecting waste products, bacteria, viruses, and other foreign substances from the tissues, and filtering them out through the lymph nodes. The lymphatic system also helps in the absorption of fats and fat-soluble vitamins from food in the digestive tract.

The endothelium is a thin layer of cells that lines the interior surface of blood vessels and lymphatic vessels. The lymphatic endothelium, specifically, is the type of endothelial cell that forms the walls of lymphatic vessels. These vessels are an important part of the immune system and play a crucial role in transporting fluid, waste products, and immune cells throughout the body.

The lymphatic endothelium helps to regulate the movement of fluids and cells between the tissues and the bloodstream. It also contains specialized structures called valves that help to ensure the unidirectional flow of lymph fluid towards the heart. Dysfunction of the lymphatic endothelium has been implicated in a variety of diseases, including lymphedema, inflammation, and cancer metastasis.

Lymphangiogenesis is the formation of new lymphatic vessels from pre-existing ones. It is a complex biological process that involves the growth, differentiation, and remodeling of lymphatic endothelial cells, which line the interior surface of lymphatic vessels. Lymphangiogenesis plays crucial roles in various physiological processes, including tissue drainage, immune surveillance, and lipid absorption. However, it can also contribute to pathological conditions such as cancer metastasis, inflammation, and fibrosis when it is dysregulated.

The process of lymphangiogenesis is regulated by a variety of growth factors, receptors, and signaling molecules, including vascular endothelial growth factor (VEGF)-C, VEGF-D, and their receptor VEGFR-3, as well as other factors such as angiopoietins, integrins, and matrix metalloproteinases. Understanding the mechanisms of lymphangiogenesis has important implications for developing novel therapies for a range of diseases associated with abnormal lymphatic vessel growth and function.

Lymphatic system, Pathology, Lymphatic pathology, Diseases of veins, lymphatic vessels and lymph nodes). ... Diseases and disorder Hodgkin's Disease/Hodgkin's Lymphoma Hodgkin lymphoma This is a type of cancer of the lymphatic system. ... Lymphatic disease is a class of disorders which directly affect the components of the lymphatic system. Examples include ... Lymphatic Diseases". "Lymphedema: Lymphatic Disorders: Merck Manual Home Edition". (Articles with short description, Short ...
... refers to the presence of the disease lymphatic filariasis in India and the social response to ... India has 40% of the world's lymphatic filariasis (LF) cases. For patients, one of the major costs of treating the disease is ... If necessary tests are ready to identify the dogs carrying the disease. Agrawal, VK; Sashindran, VK (October 2006). "Lymphatic ... The disease is timeless and present throughout Indian history. Indian physicians in the 500s wrote about the disease. In the ...
... is a World Health Organization project to eradicate the Filarioidea worms which cause the disease lymphatic filariasis and also ... "The Global Programme to Eliminate Lymphatic Filariasis: Health Impact after 8 Years". PLOS Neglected Tropical Diseases. 2 (10 ... A study review 13 years into the program found that the programs were reducing the disease, but not as quickly as planned, and ... and Impact of 13 Years of the Global Programme to Eliminate Lymphatic Filariasis on Reducing the Burden of Filarial Disease". ...
The eradication of lymphatic filariasis is the ongoing attempt to eradicate the Filarioidea worms which cause the disease ... Prior to that, the disease had been in China since ancient times. In the 1980s China had 30 million people with the disease. As ... "How Thailand eliminated lymphatic filariasis as a public health problem". Infectious Diseases of Poverty. 8 (1): 38. doi: ... The disease spreads when a mosquito transfers a worm parasite through mosquito bite. In various regions the species of worm and ...
... , also called generalized lymphatic dysplasia of Fotiou or PIEZO1 disease, is an autosomal ... Rare diseases, Lymphatic pathology, Genetic diseases and disorders). ... 616843 - LYMPHATIC MALFORMATION 6; LMPHM6". OMIM. Retrieved 2023-08-26. Fotiou, Elisavet; Martin-Almedina, Silvia; Simpson, ... "Novel mutations in PIEZO1 cause an autosomal recessive generalized lymphatic dysplasia with non-immune hydrops fetalis". Nature ...
Lymphangiomatosis is a disease involving multiple cysts or lesions formed from lymphatic vessels. Lacteal Meningeal lymphatic ... The lymphatic vessels contain valves. The general structure of lymphatics is based on that of blood vessels. There is an inner ... Afferent lymphatic vessels are only found in lymph nodes. This is in contrast to efferent lymphatic vessel which are also found ... Efferent lymphatic vessels are also found in association with the thymus and spleen. This is in contrast to afferent lymphatic ...
Insect-borne diseases, Tropical diseases, Nematodes described in 1921, Lymphatic filariasis). ... Melrose WD (2002). "Lymphatic filariasis: New insights into an old disease". Int J Parasitol. 32 (8): 947-60. doi:10.1016/S0020 ... The adult parasites reside in the lymphatics of the human host. They are found mostly in the afferent lymphatic channels of the ... and lymphatic filariasis is the target of the World Health Organization Global Program to Eliminate Lymphatic Filariasis with ...
"Lyme Disease Vaccine". Lyme Info. Retrieved April 24, 2013. "Lymphatic filariasis". www.who.int. Retrieved 2023-06-16. Hampton ... including specific infectious diseases and classes thereof List of human disease case fatality rates List of vaccine topics ... Epidemiology and Prevention of Vaccine-Preventable Diseases (13th ed.). Washington D.C.: U.S. Centers for Disease Control and ... This is a list of infectious diseases arranged by name, along with the infectious agents that cause them, the vaccines that can ...
Pathologic Basis of Veterinary Disease (Sixth ed.). Mosby. pp. 471-560.e1. doi:10.1016/b978-0-323-35775-3.00009-6. ISBN 978-0- ... The right lymphatic duct courses along the medial border of the anterior scalene at the root of the neck. The right lymphatic ... The right lymphatic duct is an important lymphatic vessel that drains the right upper quadrant of the body. It forms various ... Along with the thoracic duct, the right lymphatic duct is one of the lymphatic structures most likely to be ruptured in the ...
Australian Centre for Blood Diseases/Monash University. Retrieved 24 January 2015. The Lymphatic System. Allonhealth.com. ... Furthermore, bone marrow performs a valve-like function to prevent the backflow of lymphatic fluid in the lymphatic system.[ ... Bone marrow transplants can be conducted to treat severe diseases of the bone marrow, including certain forms of cancer such as ... Transplantation from one person to another is conducted for the treatment of severe bone marrow diseases, such as congenital ...
"Lymphatic Filariasis Endemic Countries and Territories." Lymphatic Filariasis Disease. May 2006. The Carter Center. 13 May 2006 ... LeAnne M Fox; Christopher L King (2013). "110 - Lymphatic Filariasis". In Alan J Magill; David R Hill; Tom Solomon; Edward T ... Some researchers are confident that Brugia timori filariasis may be an eradicable disease. Related filarial nematodes have been ... Brugia timori is a filarial (arthropod-borne) nematode (roundworm) which causes the disease "Timor filariasis", or "Timorian ...
"Microcystic lymphatic malformation , Genetic and Rare Diseases Information Center (GARD) - an NCATS Program". rarediseases.info ... Lymphatic malformations are congenital, developing from badly-formed lymphatic vessels in early embryonic development. Abnormal ... Elluru, RG; Balakrishnan, K; Padua, HM (August 2014). "Lymphatic malformations: diagnosis and management". Seminars in ... Low-flow vascular malformations include capillary malformations, venous malformations, and lymphatic malformations. Capillary ...
"Microcystic lymphatic malformation , Genetic and Rare Diseases Information Center (GARD) - an NCATS Program". rarediseases.info ... Patients should be aware of the associated complications of this disease such as lymphatic leaks and chronic wounds. ... Blood-filled cysts behind the eye This disease is a result of a lymphatic malformation or abnormal development of the lymphatic ... emphasizing the idea that the cause of this disease is a failure of primitive lymph sacs to connect with the lymphatic system. ...
Castleman's disease Chylothorax Kawasaki disease Kikuchi disease Lipedema Lymphangitis Lymphatic filariasis Lymphocytic ... The Wikibook Anatomy and Physiology of Animals has a page on the topic of: Lymphatic System Lymphatic System Lymphatic System ... such as lymphatic filariasis. Lymphangiomatosis is a disease involving multiple cysts or lesions formed from lymphatic vessels ... The right lymphatic duct drains the right side of the region and the much larger left lymphatic duct, known as the thoracic ...
"Chapter 7: Clinical Assessment of Venous Disease". Venous and Lymphatic Diseases. Nicos Labropoulos, Gerard Stansby. Informa ... Manual of Vascular Diseases. Sanjay Rajagopalan, Debabrata Mukherjee, Emile R. Mohler. Lippincott Williams & Wilkins. 2004. p. ...
Diseases of veins, lymphatic vessels and lymph nodes, Lymphatic vessel diseases). ... Venous and Lymphatic Disease". In Brunicardi FC, Andersen DK, Billiar TR, Dunn DL, Hunter JG, Matthews JB, Pollock RE (eds.). ... "Lymphatic filariasis: the disease and its control. Fifth report of the WHO Expert Committee on Filariasis". World Health ... Lymphedema may also be associated with accidents or certain diseases or conditions that may inhibit the lymphatic system from ...
It is recommended only as a third line treatment in graft-versus-host-disease in adults because of lack of efficacy and side ... Bielenberg DR, D'Amore PA (2008). "Judah Folkman's contribution to the inhibition of angiogenesis". Lymphatic Research and ... It is used as a second-line treatment to manage graft versus host disease and aphthous stomatitis in children and has been ... These thalidomide analogs can be used to treat different diseases, or used in a regimen to fight two conditions. Interest ...
India has 40% of the world's lymphatic filariasis (LF) cases. For the patient, one of the major costs of treating the disease ... Those 6 diseases are Lymphatic filariasis, kala-azar (Visceral leishmaniasis), Leptospirosis, Rabies, Soil-transmitted ... Chagas disease is not a problem in India. Chagas disease, like African trypanosomiasis, has a Trypanosoma parasite as its cause ... Neglected tropical diseases in India occur in areas of both urban and rural poverty. The neglected tropical diseases which ...
"Lymphatic System: Facts, Functions & Diseases". LiveScience. Retrieved 4 September 2016. Moore, Keith L.; Dalley, Arthur F.; ... The lymphatic system extracts, transports and metabolizes lymph, the fluid found in between cells. The lymphatic system is ... CDC (9 December 2019). "Know Your Risk for Heart Disease , cdc.gov". Centers for Disease Control and Prevention. Retrieved 7 ... Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a motor neuron disease which gradually reduces ...
The Carter Center, Lymphatic Filariasis Elimination Program, retrieved 17 July 2008 U.S. Centers for Disease Control, Lymphatic ... Animal diseases, Insect-borne diseases, Helminthiases, Tropical diseases, Veterinary helminthology, Parasitic diseases). ... Neglected tropical diseases Center for Disease Control and Prevention. "Lymphatic Filariasis". Retrieved 18 July 2010. ... Prevention, CDC-Centers for Disease Control and (17 September 2020). "CDC - Lymphatic Filariasis - General Information - ...
CPL resembles the human disease elephantiasis verrucosa nostra. CPL is a progressive disease, which begins below the fetlock ... The cause of CPL is not known, although it is suspected that a genetic disorder of elastin metabolism prevents the lymphatic ... There is no cure for CPL; the aim of treatment is to relieve the signs of the disease, and to slow the progression. Management ... Cardiovascular system and lymphatic vessels. Disorders of horses. Chronic progressive lymphedema in draft horses". In Zachary, ...
There is a huge burden of the neglected tropical diseases (NTDs) in Bangladesh, particularly for Kala-azar; Lymphatic ... Smoking increases the risk of cancer, heart disease, stroke, lung diseases, diabetes, chronic obstructive pulmonary disease ( ... Non-communicable diseases: diabetes, cardiovascular disease, hypertension, stroke, chronic respiratory disease, cancer ... Historically, communicable diseases formed the bulk of total diseases in developing and tropical countries such as Bangladesh. ...
FLT4 codes for VEGFR-3, which is implicated in development of the lymphatic system. Milroy's disease is also known as primary ... known as Meige disease, has its onset around the time of puberty. Meige disease is also an autosomal dominant disease. It has ... Rockson SG (October 2010). "Causes and consequences of lymphatic disease". Annals of the New York Academy of Sciences. 1207 ... May have similar health conditions, delays, disorders, and physical traits associated with other lymphatic genetic diseases and ...
It will also target lymphatic filariasis. Mutapi, Francisca (2022-08-29). "A new roadmap for neglected tropical diseases". ... One of the biggest successes was the control of Guinea worm disease (dracunculiasis). The disease was eliminated in 19 of 21 ... NTDs are not deadly diseases, and are often ignored, described as "diseases of poverty and inequality"; but are responsible for ... As the London Declaration terminated, there were considerable successes in disease control. Although no disease was eradicated ...
The role that the meningeal lymphatics plays in neurological disease is yet to be explored. It is hypothesized that they may ... The meningeal lymphatic vessels (or meningeal lymphatics) are a network of conventional lymphatic vessels located parallel to ... The role that the meningeal lymphatics play in diseases of the nervous system is an area of active research, particularly for ... The meningeal lymphatic system is composed of a network of vessels along the dural sinus in the dura which express lymphatic ...
Another 20 million have severe consequences from the disease. It is the most deadly of the neglected tropical diseases. Kato ... "Lymphatic filariasis". Fact sheet N°102. WHO Media centre. May 2015. Archived from the original on May 2, 2004. Retrieved 7 ... July 2014). "The global burden of disease study 2010: interpretation and implications for the neglected tropical diseases". ... Tropical diseases, Conditions diagnosed by stool test, Intestinal infectious diseases, Abdominal pain, Sanitation). ...
Lala S, Mulliken JB, Alomari AI, Fishman SJ, Kozakewich HP, Chaudry G. Gorham-Stout disease and generalized lymphatic anomaly- ... Gorham's disease (pronounced GOR-amz), also known as Gorham vanishing bone disease and phantom bone disease, is a very rare ... Spontaneous fractures are common and may be the first sign of the disease. A hallmark of the disease is the lack of bone ... However, others have concluded that lymphangiomatosis and Gorham's disease should be considered as a spectrum of disease rather ...
Berggreen, E; Wiig, H (2014). "Lymphatic function and responses in periodontal disease". Experimental Cell Research. 325 (2): ... In people with lung diseases, heart disease, cancer, kidney disease, immune disorders, and periodontal disease, the ... and development of diseases, as in heart failure and chronic kidney disease. The total fluid volume of the interstitium during ... The fluid spaces communicate with draining lymph nodes though they do not have lining cells or structures of lymphatic channels ...
"Lymphatic filariasis: The disease and its control. Fifth report of the WHO Expert Committee on Filariasis". World Health ... Some people with this disease may also have enlarged lymph nodes in the neck, axillae or inguinal areas. Others may have a ... Occurring most frequently in the Indian subcontinent and Southeast Asia, TPE is a clinical manifestation of lymphatic ... The diagnostic criteria for TPE include: a history supportive of exposure to lymphatic filariasis; a peripheral eosinophil ...
The disease can cause red itchy swellings below the skin called "Calabar swellings". The disease is treated with the drug ... Some patients can develop lymphatic dysfunction causing lymphedema. Episodic angioedema (Calabar swellings) in the arms and ... Loa loa filariasis is a skin and eye disease caused by the nematode worm Loa loa. Humans contract this disease through the bite ... The disease was once endemic to the western African countries of Ghana, Guinea, Guinea Bissau, Ivory Coast and Mali but has ...
Education and information about lymphatic filariasis signs and symptoms. ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ... Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People ... These people do not know they have lymphatic filariasis unless tested. A small percentage of persons will develop lymphedema. ...
Lymphatic system, Pathology, Lymphatic pathology, Diseases of veins, lymphatic vessels and lymph nodes). ... Diseases and disorder Hodgkins Disease/Hodgkins Lymphoma Hodgkin lymphoma This is a type of cancer of the lymphatic system. ... Lymphatic disease is a class of disorders which directly affect the components of the lymphatic system. Examples include ... Lymphatic Diseases". "Lymphedema: Lymphatic Disorders: Merck Manual Home Edition". (Articles with short description, Short ...
Lymphatic system problems include lymphedema and swollen glands. Learn more. ... Lymphatic diseases can affect your lymph, lymph vessels, or lymph nodes. ... Lymphatic System (For Parents) (Nemours Foundation) Also in Spanish * Overview of the Lymphatic System (Merck & Co., Inc.) Also ... Lymphatic Filariasis (Centers for Disease Control and Prevention) * Mesenteric Lymphadenitis (Mayo Foundation for Medical ...
Endpoints for Lymphatic Filariasis Programs. Emerging Infectious Diseases. 2007;13(4):608. doi:10.3201/eid1304.061063.. ... Patrick J. Lammie, Division of Parasitic Diseases, Centers for Disease Control and Prevention, 4770 Buford Hwy NE, Mailstop F- ... Grady joined the Division of Parasitic Diseases, CDC, in Atlanta, Georgia as an Emerging Infectious Diseases Training Fellow. ... Michael E, Malecela-Lazaro MN, Simonsen PE, Pedersen EM, Barker G, Kumar A, Mathematical modeling and the control of lymphatic ...
Retrieved from "https://www.wikidoc.org/index.php?title=Template:Lymphatic_disease&oldid=538718" ...
... and identify opportunities in lymphatic disease research. People with lymphedema, lipedema, and other lymphatic diseases will ... Yet to Be Charted: Lymphatic System in Health and Disease (Day 2). Download VideoCast. You can download this VideoCast and play ... Yet to Be Charted: Lymphatic System in Health and Disease (Day 2). ... Yet to Be Charted: Lymphatic System in Health and Disease (Day 1) ... Yet to Be Charted: Lymphatic System in Health and Disease (Day ...
Lymphatics in Health and Disease in the Digestive System (R01 Clinical Trial Not Allowed) RFA-DK-18-021. NIDDK ... Lymphatic vessels perform critical roles in organ functions, yet their roles in health and disease are poorly understood and ... Lymphatic vessels potentially play active roles in the relationship of gut health to the microbiome and in inflammatory disease ... Lymphatics in Health and Disease in the Digestive System (R01 Clinical Trial Not Allowed) ...
Efforts to Support Lymphatic Filariasis Elimination Activities in Indonesia Page. ... Eisai intends to continue contributing to the early elimination of the disease through the ongoing free provision of DEC ... Initiatives for Improving Access to Medicines for Non-communicable Diseases. *Research & Development for Improving Access to ... Initiatives for Improving Access to Medicines for Non-communicable Diseases. *Research & Development for Improving Access to ...
What kind of disease is lymphatic filariasis Health related question in topics Conditions Illness .We found some answers ... Lymphatic filariasis is a parasitic disease caused by microscopic, thread-like worms. It affects over 120 million people in 80 ... More Answers to "What kind of disease is lymphatic filariasis". Is lymphatic filariasis an emerging infectious disease??. http ... "What kind of disease is lymphatic filariasis",you can compare them.. Lymphatic filariasis is a parasitic disease caused by ...
... lymphatic filariasis, schistosomiasis and onchocerciasis) amenable to preventive chemotherapy (PCT). ... WHA66.12 reinforcing progress towards coordination among programmes directed against different neglected tropical diseases ( ... Neglected tropical diseases , Events and meetings , Twelfth meeting of the Regional Programme Review Group (RPRG) on lymphatic ... The status of the disease control programmes in Egypt, Sudan and Yemen was discussed during the meeting. Lymphatic filariasis ...
This manual is designed to teach personnel of national programmes to eliminate lymphatic filariasis (LF), including regional ... Welcome to the consultant roster for tropical diseases. The consultant roster provides WHO Regional Office for the Eastern ... Training in monitoring and epidemiological assessment of mass drug administration for eliminating lymphatic filariasis ... Neglected tropical diseases , News , In focus , Training in monitoring and epidemiological assessment of mass drug ...
Cystic hygroma belongs to a group of diseases recognized as lymphatic malformations and is also known as macrocystic lymphatic ... Lymphatic malformations are rare malformations of segregated lymphatic tissues that have not developed into lymphatic tissues ... Cystic Hygroma (Macrocystic Lymphatic Malformation) Imaging and Diagnosis * Sections Cystic Hygroma (Macrocystic Lymphatic ... Giant Macrocystic Lymphatic Malformation in a Neonate. J Neonatal Surg. 2017 Jan-Mar. 6 (1):21. [QxMD MEDLINE Link]. ...
Lymphatic filariasis is a tropical disease that affects about 70 million people worldwide.1 It is caused by infection with the ... Analysis Neglected Tropical Diseases in South Asia Elimination of lymphatic filariasis in South East Asia. BMJ 2019; 364 doi: ... Course of lymphatic filariasis. *. Adult filarial parasites reside in the lymphatic vessels of an infected person for up to ... Neglected tropical diseases: Lymphatic filariasis. http://www.searo.who.int/entity/vector_borne_tropical_diseases/topics/ ...
Author summary Lymphatic filariasis is a mosquito-borne infection that causes significant disabling and disfiguring clinical ... PLOS Neglected Tropical Diseases is the top Open Access tropical medicine journal, featuring an International Editorial Board ...
Cardiovascular, Lymphatic and Metabolic Disease - CLM. Research related to the investigations of cardiac function, blood vessel ... Keywords: cardiovascular disease; angiogenesis and lymphangiogenesis; lymphatic dysfunction; diabetes; obesity; heart; vessels ... Lipopolysaccharide modulates neutrophil recruitment and macrophage polarization on lymphatic vessels and impairs lymphatic ... lymphatic control of inflammation and immune responses; underlying pathophysiology of obesity, diabetes, aging, heart disease, ...
Hematologic diseases and diseases of the lymphatic system collectively. Hemic diseases include disorders involving the formed ... "Hemic and Lymphatic Diseases" by people in UAMS Profiles by year, and whether "Hemic and Lymphatic Diseases" was a major or ... "Hemic and Lymphatic Diseases" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... Below are the most recent publications written about "Hemic and Lymphatic Diseases" by people in Profiles over the past ten ...
Eisais news release EISAI RECEIVES PREQUALIFICATION FROM WORLD HEALTH ORGANIZATION FOR LYMPHATIC FILARIASIS MEDICINE ... 2. About Lymphatic Filariasis. Lymphatic filariasis is a parasitic disease that is transmitted to humans by the bite of a ... The lymphatic filariasis medicine DEC is in short supply worldwide, which poses a major obstacle in eliminating the disease. As ... The disease also causes patients and their families much emotional distress. Today, lymphatic filariasis affects an estimated ...
Cardiovascular & Lymphatic Systems. Carolina provides all the materials you need to help students study the anatomy of the ...
8 External Disease and Cornea. Chapter 12: Clinical Approach to Neoplastic Disorders of the Conjunctiva and Cornea. Lymphatic ...
Here the authors profile lineage-specific lncRNAs in human dermal lymphatic and blood vascular endothelial cells (LECs and BECs ... We determine a comprehensive map of lineage-specific lncRNAs in human dermal lymphatic and blood vascular endothelial cells ( ... Cueni, L. N. & Detmar, M. The lymphatic system in health and disease. Lymphat. Res. Biol. 6, 109-122 (2008). ... Dieterich, L. C., Seidel, C. D. & Detmar, M. Lymphatic vessels: new targets for the treatment of inflammatory diseases. ...
... organized a clinical experts meeting on lymphatic filariasis (LF). The meeting objectives were; to identify the unmet needs for ... A C Dhariwal, Director, National Vector Borne Disease Control Program. Swarup Kumar Sarkar, Director Communicable Disease, WHO- ... The DNDi Indian office and the Indian Council of Medical Research (ICMR) organized a clinical experts meeting on lymphatic ... PacELF - Eliminating lymphatic filariasis in the Asia Pacific. Kazuyo Ichimori, Professor, Institute of Tropical Medicine, ...
Bancroftian and Brugian Lymphatic Filariasis - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the MSD ... Chronic filarial disease develops insidiously after many years. In most patients, asymptomatic lymphatic dilation occurs, but ... Other forms of chronic filarial disease are caused by disruption of lymphatic vessels or aberrant drainage of lymph fluid, ... Lymphatic filariasis is transmitted by mosquitoes; infective larvae migrate to the lymphatics, where they develop into adult ...
Targeted Lymphatic and Microvessel Treatments in metabolic-DISease HFpEF - Inserm U1096 ... lymphatic vessel physiology and morphology, hemogenic endothelium, endothelial cell phenotypes, heart development, progenitor ... macrophage miRNA impact on lymphatic and blood endothelial cell dysfunction in MetS. ...
Chen, Z, Schwulst, SJ & Mentis, AFA 2021, Correction: APOE4-mediated Alzheimer disease and "Vascular"-"Meningeal Lymphatic" ... Dive into the research topics of Correction: APOE4-mediated Alzheimer disease and "Vascular"-"Meningeal Lymphatic" components ... T2 - APOE4-mediated Alzheimer disease and "Vascular"-"Meningeal Lymphatic" components: towards a novel therapeutic era? ( ... Correction: APOE4-mediated Alzheimer disease and "Vascular"-"Meningeal Lymphatic" components: towards a novel therapeutic era ...
Liver disease.. Lymphatic system diseases. Your small intestine absorbs fats into your bloodstream through lymph vessels. ... Infectious diseases such as Whipples disease and tropical sprue.. *Inflammatory bowel diseases such as ulcerative colitis and ... Some gastrointestinal diseases, such as celiac disease and inflammatory bowel disease, cause general malabsorption of all kinds ... Diseases of the lymphatic system that block these vessels can compromise the absorption of fats. Intestinal lymphangiectasia ...
Lymphoedema and hydrocoele are the two most common clinical manifestations of lymphatic filariasis (LF). In order to ... Pathogenesis of lymphatic disease in bancroftian filariasis: a clinical perspective. Parasitol Today. 2000;16:544-8. ... BMC Infectious Diseases volume 15, Article number: 214 (2015) Cite this article ... Examples of mobile health (or mHealth) can be found in a variety of applications including disease mapping/surveillance [10, 11 ...
Use this guide on lymph detox for Lyme disease to learn how to cleanse your lymphatic system and help ease inflammation, ... Lymph Detox for Lyme Disease: How to Cleanse Your Lymphatic System. Home/Health-Articles/Lymph Detox for Lyme Disease: How to ... Lymph Detox for Lyme Disease: How to Cleanse Your Lymphatic System by Jenny Lelwica Buttaccio Posted 3/5/20 If youve dealt ... Lymph Detox for Lyme Disease: How to Cleanse Your Lymphatic System by Jenny Lelwica Buttaccio Posted 3/5/20 If youve dealt ...
Elimination of Lymphatic Filariasis in India. In 1997, WHO and its Member States made a commitment to eliminate Lymphatic ... National Roadmap for Elimination of Lymphatic Filariasis (ELF). *Guidelines for Drug Distributors in Elimination of Lymphatic ... Accelerated Plan for Elimination of Lymphatic Filariasis 2018 launched in 10 Global Alliance Elimination of Lymphatic ... Twin Pillar Strategy for Elimination of Lymphatic Filariasis. *Annual Mass Drug Administration (MDA) of single dose of DEC ( ...
Monrovia, June 23, 2022: The management and treatment of any disease is critical to prevent outbreaks and ensure positive ... where adults as well will be targeted and this donation is in line with the global fight to eliminate lymphatic filariasis. We ... WHOs work on schistosomiasis and filariasis is part of an integrated approach in the control of neglected tropical diseases. ... supplies will be distributed to 9 counties that have been earmarked due to their high prevalence rates in lymphatic disease ...
  • lymphatic diseases include disorders relating to lymph, lymph nodes, and lymphocytes. (uams.edu)
  • Lymph nodes are usually small, bean-shaped structures that filter harmful substances and waste from the lymphatic fluid. (remedypost.com)
  • Conditions that cause swollen lymph nodes, such as autoimmune diseases and hormonal imbalances, may indirectly contribute to acne. (remedypost.com)
  • Lymphatic drainage facials and massages stimulate the lymphatic system and promote waste removal, potentially reducing the risk of swollen lymph nodes. (remedypost.com)
  • Kikuchi Fujimoto disease (KFD) is a rare condition that affects a person's lymph nodes. (medicalnewstoday.com)
  • KFD is a very rare disease that can cause a person to have swollen lymph nodes. (medicalnewstoday.com)
  • Rosai-Dorfman disease is a rare disorder characterized by overproduction (proliferation) and accumulation of a specific type of white blood cell (histiocyte) in the lymph nodes of the body (lymphadenopathy), most often those of the neck (cervical lymphadenopathy). (rarediseases.org)
  • The adult filarial worms primarily reside in the lymphatic vessels and lymph nodes. (who.int)
  • As a result, the scope of the current WHO Regional Office-RPRG meeting is being broadened to involve discussions on three major neglected tropical diseeases (lymphatic filariasis, schistosomiasis and onchocerciasis) amenable to preventive chemotherapy. (who.int)
  • Lymphatic filariasis and schistosomiasis are present in Egypt, Sudan and Yemen, whereas onchocerciasis is transmitted in Sudan and Yemen only. (who.int)
  • Lymphatic disease is a class of disorders which directly affect the components of the lymphatic system. (wikipedia.org)
  • Similar to the action of the cardiovascular system , many of the functions of the lymphatic system happen without much awareness on your part. (rawlsmd.com)
  • In continued efforts to ensure the government of Liberia is prepared to respond to vector borne infections such as Schistosomiasis and lymphatic filariasis, the World Health Organization (WHO) in Liberia with support from the WHO African Regional Office and HQ, today donated 2,512,000 tablets of praziquantel and 12,450 testing strips for Filariasis to the Ministry of Health in Liberia. (who.int)
  • WHO's work on schistosomiasis and filariasis is part of an integrated approach in the control of neglected tropical diseases. (who.int)
  • Schistosomiasis gets the nickname "snail fever" from freshwater snails carrying the disease. (borgenproject.org)
  • Examples include Castleman's disease and lymphedema. (wikipedia.org)
  • Globally, more than 1 billion persons are at risk for lymphatic filariasis (LF), a mosquito-transmitted parasitic infection that causes lymphedema and hydrocele. (cdc.gov)
  • People with lymphedema, lipedema, and other lymphatic diseases will share their personal experiences. (nih.gov)
  • Featured topics include lymphedema and the role of lymphatics in obesity. (nih.gov)
  • In most patients, asymptomatic lymphatic dilation occurs, but chronic inflammatory responses to adult worms and secondary bacterial infections may result in chronic lymphedema of the affected body area. (msdmanuals.com)
  • Chronic pitting lymphedema of a lower extremity can progress to elephantiasis (chronic lymphatic obstruction). (msdmanuals.com)
  • Although lymphedema may not be a classic symptom of tick-borne diseases, Lyme patients can potentially develop it. (rawlsmd.com)
  • LE&RN, in partnership with Stanford University, has established the International Lymphatic Disease and Lymphedema Patient Registry and Biorepository to collect information about individuals diagnosed with a lymphatic disease. (lymphnotes.com)
  • Secondary lymphedema can result when the lymphatic system is altered due to injury, infection, or problems with major organs. (dukehealth.org)
  • Although it is considered the "gold standard" for confirming a lymphedema diagnosis, it's reserved for select people and surgery planning because it requires injecting a radioactive dye into an already overloaded lymphatic system. (dukehealth.org)
  • Most notably, it can cause lymphedema (swelling) of limbs and genital disease, including hydrocele (swelling of the scrotum), chylocele, and swelling of the penis. (who.int)
  • One of them is Lymphatic Filariasis, also known as Elephantiasis. (haitiinnovation.org)
  • The disease is better known as elephantiasis. (borgenproject.org)
  • Lymphatic filariasis (LF), commonly known as elephantiasis, is a painful and profoundly disfiguring disease. (who.int)
  • The purpose of this FOA is to invite applications that investigate aspects of lymphatic vessel physiology, development and pathophysiology related to health and diseases of the digestive system. (nih.gov)
  • The 2020 Gordon Research Conference on Lymphatics will bring together leading international scientists and clinicians working across all aspects of lymphatic vessel biology to discuss the latest advances in this exciting and dynamic field. (grc.org)
  • The workshop aims to improve how we manage and treat lymphatic disorders. (nih.gov)
  • Hemic diseases include disorders involving the formed elements (e.g. (uams.edu)
  • Hemic and Lymphatic Diseases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uams.edu)
  • This graph shows the total number of publications written about "Hemic and Lymphatic Diseases" by people in UAMS Profiles by year, and whether "Hemic and Lymphatic Diseases" was a major or minor topic of these publications. (uams.edu)
  • Below are the most recent publications written about "Hemic and Lymphatic Diseases" by people in Profiles over the past ten years. (uams.edu)
  • The World Health Organization (WHO) and other global health bodies have initiated programs aimed at eliminating lymphatic filariasis as a public health problem. (who.int)
  • Given that infectious diseases do not respect borders, this initiative seems an excellent opportunity for collaboration between Haiti and the Dominican Republic. (haitiinnovation.org)
  • Neglected tropical diseases (NTDs) are a group of infectious diseases that thrive in poor and rural settings, affecting 1.6 billion of the world's poorest and most vulnerable people, including 850 million children. (kit.nl)
  • Chronic infection causes lymphatic dysfunction, resulting in progressive, irreversible swelling of the limbs and genitals ( box 1 ). (bmj.com)
  • Once transmitted, it causes lymphatic dysfunction. (eisai.com)
  • Thereafter, a distinct subpopulation of endothelial cells lining the cardinal vein starts differentiating by expressing the TF PROX1, the master regulator of lymphatic endothelial cell (LEC) identity, via the TFs SOX18 and COUPTFII. (nature.com)
  • Future research planned includes determining the molecular basis for fluid flow-induced differences in endothelial cell migration, optimization of streamlined stent design, and pre-clinical studies of streamlined stents in coronary heart disease animal models. (umass.edu)
  • Filarial infection can also cause tropical pulmonary eosinophilia syndrome, although this syndrome is typically found in persons living with the disease in Asia. (cdc.gov)
  • The lymphatic system clears away infection and keeps your body fluids in balance. (medlineplus.gov)
  • While infection is usually acquired during childhood, symptoms often gradually appear over several years, with the most serious manifestations of the disease occurring in adulthood. (eisai.com)
  • Lymphatic filariasis is infection with any of 3 species of Filarioidea . (msdmanuals.com)
  • Infection over long periods leads to damage of the lymphatic system, which can manifest as lymphoedema and hydrocele (scrotal swelling). (kit.nl)
  • [ 1 ] Although the prevalence of MAI infection has increased following the epidemic of acquired immunodeficiency syndrome (AIDS), MAI infection remains a rare cause of skin disease. (medscape.com)
  • In the United States, Mycobacterium avium-intracellulare (MAI, or MAC) infection is considered a nonreportable infectious disease. (medscape.com)
  • This coincidence concords with the fact that DMAI infection often occurs in association with HIV disease. (medscape.com)
  • A review of 8 cases of cutaneous MAI infection occurring secondary to disseminated disease found a median patient age of 22.2 years, with a range of 2-28 years. (medscape.com)
  • Shira Shafir] We know that people with compromised or suppressed immune systems are more likely to get severe disease because their immune systems are not able to control the infection and this allows the fungus to spread from the lungs to other organs. (cdc.gov)
  • We determine a comprehensive map of lineage-specific lncRNAs in human dermal lymphatic and blood vascular endothelial cells (LECs and BECs), combining RNA-Seq and CAGE-Seq. (nature.com)
  • The blood and lymphatic vascular systems are essential for the efficient transport of oxygen, nutrients, signaling molecules, and leukocytes to and from peripheral tissues, the removal of waste products, and the preservation of fluid homeostasis. (nature.com)
  • Correction: APOE4-mediated Alzheimer disease and "Vascular"-"Meningeal Lymphatic" components: towards a novel therapeutic era? (northwestern.edu)
  • Dive into the research topics of 'Correction: APOE4-mediated Alzheimer disease and "Vascular"-"Meningeal Lymphatic" components: towards a novel therapeutic era? (northwestern.edu)
  • Intratumoral lymphatic vascular density is an independent factor for disease-free and overall survival in advanced stage oral squamous cell carcinoma. (bvsalud.org)
  • The lymphatic vascular density (LVD), blood vascular density (BVD), and neoformed vascular density (NVD) were assessed by counting positive reactions in 4 hotspot areas, both intratumoral (IT) and peritumoral (PT), at high magnification (× 40). (bvsalud.org)
  • Although lipid lowering and lifestyle management have reduced the number of deaths from heart disease, coronary artery disease still dominates as the major cause of death in people with heart disease, so we haven't cured the disease yet," said Sessa, who directs Yale's vascular biology and therapeutics program. (constantcontact.com)
  • The third sustainable development goal calls for elimination of neglected tropical diseases, including filariasis, by 2020. (bmj.com)
  • In 1997, WHO and its Member States made a commitment to eliminate Lymphatic Filariasis (LF) as public health problem by 2020 through World Health Assembly Resolution WHA 50.29. (mohfw.gov.in)
  • In 1997, The World Health Assembly adopted resolution WHA 50.29, for Elimination of Lymphatic Filariasis as a global public health problem by 2020. (mohfw.gov.in)
  • Building on the success of previous years, the 2020 Gordon Research Conference on Lymphatics will be preceded by a Gordon Research Seminar on Lymphatics, themed "Interdisciplinary Perspectives on Lymphatic Function in Neglected Diseases" and organized by Elizabeth Haining and Rene Haegerling. (grc.org)
  • We invite you to join us in Ventura, CA, in March 2020 for the preeminent lymphatic vessel meeting of the year! (grc.org)
  • There are growing demands for predicting the prospects of achieving the global elimination of neglected tropical diseases as a result of the institution of large-scale nation-wide intervention programs by the WHO-set target year of 2020. (biomedcentral.com)
  • We describe a modeling platform that addresses this problem of upscaling from local settings to facilitate predictions at regional levels by the discovery and use of locality-specific transmission models, and we illustrate the utility of using this approach to evaluate the prospects for eliminating the vector-borne disease, lymphatic filariasis (LF), in sub-Saharan Africa by the WHO target year of 2020 using currently applied or newly proposed intervention strategies. (biomedcentral.com)
  • Partly, this is in response to the urgent policy demands for more accurate scientific information for determining if the roadmap set by the World Health Organization (WHO), based on sustaining and expanding drug access programs, will accomplish the elimination or control of these neglected tropical diseases (NTDs) by the target year of 2020 [ 6 ]. (biomedcentral.com)
  • There have been companies donating to help fight the disease, such as Johnson and Johnson, pledging to donate 200 million tablets of mebendazole by 2020, and GlaxoSmithKline, donating one billion tablets of albendazole a year. (borgenproject.org)
  • The World Health Assembly has adopted Resolution WHA51.11 which is geared towards eliminating the disease by 2020. (borgenproject.org)
  • Lymphatic filariasis is a parasitic disease caused by microscopic, thread-like worms. (themedicalquestions.com)
  • Lymphatic filariasis is a parasitic disease that is transmitted to humans by the bite of a mosquito. (eisai.com)
  • We show how a computational platform that couples site-specific data discovery with model fitting and calibration can allow both learning of local LF transmission models and simulations of the impact of interventions that take a fuller account of the fine-scale heterogeneous transmission of this parasitic disease within endemic countries. (biomedcentral.com)
  • Many of these functions include key roles of lymphatic vessels, yet the roles of lymphatics, the character of the vessels in the intestinal environment and key regulators of lymphatic function in intestinal health and disease remain understudied. (nih.gov)
  • The lymphatic system is a network of tissues and organs. (medlineplus.gov)
  • Studies to understand the factors that control local lymphatic vessel functional anatomy and physiology and development during health or disease in this system and its organs, and the mechanisms by which alterations of lymphatic vessel function affect organ function, are of interest. (nih.gov)
  • However, studies with the major focus on immune mechanisms, role of lymphatics in cancer metastasis and study of lymphatic vessels in organs other than those from the digestive system will not be considered responsive. (nih.gov)
  • Lymphatic vessels within different organs and in different physiological and pathological processes show a remarkable plasticity and heterogeneity, reflecting their functional specialization. (nih.gov)
  • In addition, lymphatic endothelial cells of different organs have been recently shown to have alternative developmental origins, which may contribute to the development of the diverse lymphatic vessel and endothelial functions seen in the adult. (nih.gov)
  • The lymphatic vessels and secondary lymphoid organs (SLOs) are arranged in a manner that optimizes interactions among antigens, APCs, and innate and adaptive effector cells. (jci.org)
  • In some cases of Rosai-Dorfman disease, the accumulation of histiocytes into masses may cause compression of vital organs potentially resulting in serious complications. (rarediseases.org)
  • In May 2013, the World Health Assembly passed resolution WHA66.12 reinforcing progress towards coordination among programmes directed against different neglected tropical diseases (NTDs). (who.int)
  • Please refer to the following notes for further information on NTDs, lymphatic filariasis, the London Declaration on NTDs, and the WHO Prequalification of Medicines Programme. (eisai.com)
  • There are 149 countries and territories where NTDs are endemic, at least 100 of which are endemic for 2 or more of these diseases, and 30 countries and territories that are endemic for 6 or more. (eisai.com)
  • Participants of the Twelfth meeting of the Regional Programme Review Group (RPRG) on lymphatic filariasis elimination and other preventive chemotherapy programmes The twelfth meeting of the Regional Programme Review Group (RPRG) on lymphatic filariasis elimination and other preventive chemotherapy programmes took place in Sharm El Sheikh, Egypt, from 21 to 23 October 2013. (who.int)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
  • Protocols for collecting data from sentinel sites were approved by the Centers for Disease Control and Prevention Institutional Review Board and the Ethics Committee at Hopital Ste. Croix. (cdc.gov)
  • This is a joint statement of the American Thoracic Society and the Centers for Disease Control. (cdc.gov)
  • Historically, the American Thoracic Society (ATS) and the Centers for Disease Control (CDC) have provided guidance on the diagnosis, treatment, prevention, and control of tuberculosis in the United States and Canada. (cdc.gov)
  • The US Centers for Disease Control and Prevention (CDC) surveillance data from Houston and Atlanta suggest an incidence of 1 case per 100,000 persons per year. (medscape.com)
  • Announcer] This program is presented by the Centers for Disease Control and Prevention. (cdc.gov)
  • Kapil and I come to you from the Centers for Disease Control and Prevention, Agency for Toxic Substances and Disease Registry in Atlanta, Georgia. (cdc.gov)
  • This manual is designed to teach personnel of national programmes to eliminate lymphatic filariasis (LF), including regional and district health personnel, the essential elements of monitoring and evaluating national programmes to eliminate LF. (who.int)
  • The World Health Organization launched the global programme to eliminate lymphatic filariasis in 2000. (bmj.com)
  • Managing morbidity and preventing disability amongst those already affected by LF is one of the main components of the Global Programme to Eliminate Lymphatic Filariasis (GPELF), and as such effective morbidity management strategies are vital for public health improvement. (biomedcentral.com)
  • Subsequent to that Global Alliance to Eliminate Lymphatic Filariasis (GAELF) has been formed in 2000. (mohfw.gov.in)
  • For high level advocay - United to Eliminate Lymphatic National Symposium Filariasis held on 30th October 2019 at Pravasi Bharatiya Kendra, New Delhi inaugurated by Hon'ble Union Health Minister. (mohfw.gov.in)
  • These medications and testing kits are donated as part of the global fight to eliminate lymphatic filariasis. (who.int)
  • The medication and supplies will be distributed to 9 counties targeting school going children with an exception of the 4 counties Bong, Lofa, Maryland and Nimba, where adults as well will be targeted and this donation is in line with the global fight to eliminate lymphatic filariasis. (who.int)
  • The New York Times recently carried an article on the Carter Center's joint Haiti/Dominican Republic initiative to eliminate malaria and lymphatic filariasis from the island of Hispaniola, which both countries share. (haitiinnovation.org)
  • The lymphatic vasculature has garnered immense attention over the last decade, fueled by advances in our ability to recognize and manipulate lymphatic vessels, together with discoveries that have illuminated key roles for the lymphatic vasculature in human health and disease. (grc.org)
  • Lee Y, Chakraborty S, Meininger CJ, Muthuchamy M. Insulin resistance disrupts cell integrity, mitochondrial function, and inflammatory signaling in lymphatic endothelium . (tamu.edu)
  • Chakraborty S, Zawieja DC, Davis MJ, Muthuchamy M. MicroRNA signature of inflamed lymphatic endothelium and role of miR-9 in lymphangiogenesis and inflammation [published correction appears in Am J Physiol Cell Physiol. (tamu.edu)
  • Cardiovascular disease causes one-third of deaths worldwide and represents an urgent threat to global health. (nature.com)
  • The scientific, clinical, pharmacological and public health communities have coordinated efforts to prevent, diagnose, treat and cure cardiovascular disease. (nature.com)
  • Rather than supporting specific research projects, the Merit Awards support scientists - those who propose novel approaches to major research challenges in cardiovascular disease and stroke that have the potential to produce an unusually high impact. (constantcontact.com)
  • About 51 million people were infected as of 2018, and 40 million have been disfigured by the disease. (msdmanuals.com)
  • Accelerated Plan which include Triple Drug Therapy (IDA) was launched in the Global Alliance Elimination of Lymphatic Filariasis (GAELF) meeting held during 13th to 15th June 2018 by Hon'ble Union Health Minister and Hon'ble Minister of State. (mohfw.gov.in)
  • In endemic countries, lymphatic filariasis has a major social and economic impact. (who.int)
  • Lymphatic malformations are rare malformations of segregated lymphatic tissues that have not developed into lymphatic tissues with normal connections of regional lymphatic drainage and have resulted in dilatation of abnormal channels. (medscape.com)
  • India alone harbours 40% of the world's burden of disease. (bmj.com)
  • Eisai Co., Ltd. (Headquarters: Tokyo, President & CEO: Haruo Naito, "Eisai") announced today that it has received prequalification from the World Health Organization (WHO) for diethylcarbamazine citrate (DEC) 100 mg tablets manufactured at its Vizag Plant in India for the treatment of lymphatic filariasis, a neglected tropical disease (NTD). (eisai.com)
  • The National Health Policy (2002) has set the goal of Elimination of Lymphatic Filariasis in India by 2015. (mohfw.gov.in)
  • Diagnosis is by detection of microfilariae in blood or lymphatic tissue biopsy specimens, ultrasound visualization of adult worms in lymphatics, or serologic testing. (msdmanuals.com)
  • Although each test helps to narrow down the final diagnosis they become increasingly expensive and time-consuming to perform, and rapid action is often important when treating a disease. (elifesciences.org)
  • This revision has been made primarily to update the information on tuberculin skin testing and laboratory services for the diagnosis of tuberculosis, and to remove material pertaining to nontuberculous mycobacterial diseases, which will henceforth be dealt with separately. (cdc.gov)
  • Many children have advanced disease at the time of diagnosis. (uhhospitals.org)
  • In some populations, we suspect that possibility of death increases because poor access to health care services might delay diagnosis, resulting in more severe disease. (cdc.gov)
  • Cystic hygroma belongs to a group of diseases recognized as lymphatic malformations and is also known as macrocystic lymphatic malformation or cystic lymphangioma . (medscape.com)
  • This category is a broad overview of celiac disease including development, presentation, symptoms, and treatment. (glutenfreeworks.com)
  • The symptoms and physical findings associated with Rosai-Dorfman disease vary depending upon the specific areas of the body that are affected. (rarediseases.org)
  • The symptoms and physical findings associated with Rosai-Dorfman disease vary greatly from one person to another depending upon the extent of the disorder and the specific organ systems affected. (rarediseases.org)
  • Many individuals with Rosai-Dorfman disease do not develop any additional symptoms of the disorder (asymptomatic). (rarediseases.org)
  • Other individuals have a multitude of the most severe symptoms of end-stage liver disease and a limited chance for survival. (medscape.com)
  • Specific medical therapies may be applied to many liver diseases in an effort to diminish symptoms and to prevent or forestall the development of cirrhosis. (medscape.com)
  • In optimal settings, MRI can provide exquisite anatomic detail, and it can be especially helpful in identifying additional pathology, as well as in determining the extent of the disease. (medscape.com)
  • The lymphatic system is a crucial component of nutrient and hormone absorption, fluid homeostasis and immunity. (nih.gov)
  • The lymphatic system is a crucial part of the immune system, helping to maintain overall health by removing waste and regulating fluid balance. (remedypost.com)
  • Neglected tropical diseases are transmitted diseases caused by parasites, and are usually found in tropical and subtropical regions. (borgenproject.org)
  • Lymphatic filariasis is caused by infections from parasites called filarial worms and leads to abnormal enlargements of body parts, which causes great pain. (borgenproject.org)
  • Trachoma is another eye disease that is much more severe than River Blindness. (borgenproject.org)
  • Infective larvae from the mosquito migrate to the lymphatics, where they develop into threadlike adult worms within 6 to 12 months. (msdmanuals.com)
  • Efforts to control lymphatic filariasis include mosquito control, mass drug administration to reduce transmission and treatment of individual cases. (who.int)
  • I recently attended a Regional meeting on organized by WHO in Brazzaville where elimination and eradication of vector borne diseases were highlighted. (who.int)
  • This year World Health Day focuses on vector-borne diseases. (cdc.gov)
  • More than half the world is at risk from vector-borne diseases. (cdc.gov)
  • The lymphatic system runs parallel to the circulatory system, and lymphatic vessels carry fluid throughout the body. (remedypost.com)
  • Exercise helps the muscles become more efficient in pumping lymphatic fluid throughout the body. (dukehealth.org)
  • Adenolymphangitis episodes usually precede onset of chronic disease by ≥ 2 decades. (msdmanuals.com)
  • Chronic filarial disease develops insidiously after many years. (msdmanuals.com)
  • Globally, approximately 40 million people are affected by the clinical manifestations of lymphatic filariasis (LF), which ranges from acute attacks of filarial fever (acute dermatolymphangioadenitis or ADLAs) to chronic manifestations of lymphoedema and hydrocoele [ 1 ]. (biomedcentral.com)
  • Because it is a chronic disease people can go years without treatment, so it is important to monitor the disease for any changes. (cancercare.org)
  • CT thorax scan of a 77-year-old woman who presented with chronic cough and sputum production, without a history of underlying preexisting lung disease. (medscape.com)
  • Chronic inflammation caused by the immune response can lead to the thickening of the walls of the lymphatic vessels and reduced lymphatic flow. (who.int)
  • The lymphatic system plays an important role in uptake of dietary fat and clearance of cholesterol from peripheral tissues and has been implicated in several disease states such as obesity, metabolic syndrome and inflammatory bowel disease (IBD). (nih.gov)
  • The entire lymphatic system is an integral part of your immune system . (rawlsmd.com)
  • A person's lymphatic system is part of their immune system . (medicalnewstoday.com)
  • MAI is an opportunistic pathogen that usually causes disease in the weakened immune system. (medscape.com)
  • The lymphatic system plays a vital role in your immune system by circulating lymph fluid -- made up of bacteria-fighting white blood cells, proteins, and other substances -- throughout your body. (dukehealth.org)
  • In 2000, annual mass administration of diethlycarbamazine and albendazole began in Leogane Commune, Haiti, to interrupt transmission of lymphatic filariasis (LF). (cdc.gov)
  • NHL results when the cells in the lymphatic system (lymphocytes) are changed (mutated) and grow out of control. (uhhospitals.org)
  • On this Page Malaria The Reality of Outbreak Investigations: Dengue in Angola Chagas disease and the kissing bug Lymphatic filariasis: Spotlight on elimination in Haiti April 7 marks World Health Day. (cdc.gov)
  • Hosted by the NHLBI and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) in coordination with the Trans-NIH Lymphatic Coordinating Committee, the workshop will bring together basic, clinical, and translational scientists, along with members of the lymphatics community, to explore the latest advances in the field and share research progress. (nih.gov)
  • The DND i Indian office and the Indian Council of Medical Research (ICMR) organized a clinical experts meeting on lymphatic filariasis (LF). (dndi.org)
  • Lymphoedema and hydrocoele are the two most common clinical manifestations of lymphatic filariasis (LF). (biomedcentral.com)
  • Twin pillar strategies of Mass Drug Administration (MDA) for interruption of transmission i.e. no new case and Morbidity Management and Disability Prevention (MMDP) for catering the disease afflicted patients were adopted for elimination. (mohfw.gov.in)
  • Annual Mass Drug Administration (MDA) of single dose of DEC (Diethylcarbamazine citrate) and Albendazole for 5 years or more to the eligible population (except pregnant women, children below 2 years of age and seriously ill persons) to interrupt transmission of the disease. (mohfw.gov.in)
  • In this article ref. 12 was incorrect and should have been "Nasrabady SE, Rizvi B, Goldman JE, Brickman AM. White matter changes in Alzheimer's disease: a focus on myelin and oligodendrocytes. (northwestern.edu)
  • In 2004, Elimination of Lymphatic Filariasis (ELF) programme was launched covering 202 endemic districts in 20 States/UTs. (mohfw.gov.in)
  • Their presence can cause damage and obstruction in the lymphatic system. (who.int)
  • Diseases and disorder Hodgkin's Disease/Hodgkin's Lymphoma Hodgkin lymphoma This is a type of cancer of the lymphatic system. (wikipedia.org)
  • Many cancer cells are spread by way of the lymphatic system, producing cluster of tumor cells where they lodge. (easynotecards.com)
  • NHL is cancer that starts in the lymphatic system. (uhhospitals.org)
  • Emerging research on the roles of stromal cells in modulating adaptive immune responses has included a new focus on lymphatic endothelial cells (LECs). (jci.org)
  • Lymphatic endothelial cells (LECs) themselves have been shown to play active roles in controlling their transport functions and in directly communicating with immune cells to modulate their immediate and downstream functions. (jci.org)
  • While we particularly focus on LEC interactions with DCs and T cells, we also highlight features that support immune regulation, including the structure and function of lymphatic vessels and the compartmentalization of the LN stroma, which help control the manner in which LECs can interface with immune cells. (jci.org)
  • This study aimed to evaluate the correlation between the lymphatic and blood vessel densities with prognostic outcomes in advanced stage OSCC. (bvsalud.org)
  • Standing water creates an ideal breeding ground for mosquitos that carry malaria and other diseases. (haitiinnovation.org)
  • Some of the world's most accomplished disease experts-including several of my colleagues in CDC's Division of Parasitic Diseases and Malaria (DPDM)-are gathering in Geneva this week at the NTD Summit 2017. (cdc.gov)
  • Lymphatic filariasis is among the world's leading causes of permanent and long-term disability. (themedicalquestions.com)
  • In the digestive system, lymphatic vessel function is interwoven with organ function, both anatomically and physiologically and these vessels lie at the nexus of critical hormonal, digestive and immune functions. (nih.gov)
  • Most people think of the liver and digestive system when they consider where detox happens in the body, but there's another system that plays a crucial role in detoxification that you might not be as familiar with: the lymphatic system . (rawlsmd.com)