Lod Score
Genetic Linkage
Pedigree
Chromosome Mapping
Genetic Markers
Genes, Dominant
Chromosomes, Human, Pair 2
Microsatellite Repeats
Chromosomes, Human, Pair 1
Genetic Heterogeneity
The presence of apparently similar characters for which the genetic evidence indicates that different genes or different genetic mechanisms are involved in different pedigrees. In clinical settings genetic heterogeneity refers to the presence of a variety of genetic defects which cause the same disease, often due to mutations at different loci on the same gene, a finding common to many human diseases including ALZHEIMER DISEASE; CYSTIC FIBROSIS; LIPOPROTEIN LIPASE DEFICIENCY, FAMILIAL; and POLYCYSTIC KIDNEY DISEASES. (Rieger, et al., Glossary of Genetics: Classical and Molecular, 5th ed; Segen, Dictionary of Modern Medicine, 1992)
Haplotypes
Genome, Human
Chromosomes, Human, Pair 6
Chromosomes, Human, Pair 12
Chromosomes, Human, Pair 16
Chromosomes, Human, Pair 19
Chromosomes, Human, Pair 7
Penetrance
Genotype
Chromosomes, Human, Pair 10
Chromosomes, Human, Pair 4
Family Health
Chromosomes, Human, Pair 5
Chromosomes, Human, Pair 20
Quantitative Trait, Heritable
Genetic Predisposition to Disease
Chromosomes, Human, Pair 3
Phenotype
Chromosomes, Human, Pair 13
Chromosomes, Human, Pair 17
X Chromosome
Chromosomes, Human, Pair 9
Models, Genetic
Chromosomes, Human, Pair 11
Age of Onset
Chromosomes, Human, Pair 15
Cataract
Chromosomes, Human, Pair 8
Chromosomes, Human
Alleles
Matched-Pair Analysis
Genetic Testing
Siblings
Chromosomes, Human, Pair 18
Chromosomes, Human, Pair 14
Polymorphism, Genetic
The regular and simultaneous occurrence in a single interbreeding population of two or more discontinuous genotypes. The concept includes differences in genotypes ranging in size from a single nucleotide site (POLYMORPHISM, SINGLE NUCLEOTIDE) to large nucleotide sequences visible at a chromosomal level.
Recombination, Genetic
Likelihood Functions
Polymorphism, Single Nucleotide
Polymorphism, Restriction Fragment Length
Retinitis Pigmentosa
Crosses, Genetic
Linkage Disequilibrium
Gene Frequency
Multifactorial Inheritance
Founder Effect
A phenomenon that is observed when a small subgroup of a larger POPULATION establishes itself as a separate and isolated entity. The subgroup's GENE POOL carries only a fraction of the genetic diversity of the parental population resulting in an increased frequency of certain diseases in the subgroup, especially those diseases known to be autosomal recessive.
Chromosomes, Human, Pair 22
Chromosomes, Mammalian
Genome-Wide Association Study
Genetic Diseases, Inborn
Reproducibility of Results
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Severity of Illness Index
Hearing Loss, Sensorineural
Mutation
Heterozygote
DNA, Satellite
Highly repetitive DNA sequences found in HETEROCHROMATIN, mainly near centromeres. They are composed of simple sequences (very short) (see MINISATELLITE REPEATS) repeated in tandem many times to form large blocks of sequence. Additionally, following the accumulation of mutations, these blocks of repeats have been repeated in tandem themselves. The degree of repetition is on the order of 1000 to 10 million at each locus. Loci are few, usually one or two per chromosome. They were called satellites since in density gradients, they often sediment as distinct, satellite bands separate from the bulk of genomic DNA owing to a distinct BASE COMPOSITION.
Hand Deformities, Congenital
Neoplastic Syndromes, Hereditary
The condition of a pattern of malignancies within a family, but not every individual's necessarily having the same neoplasm. Characteristically the tumor tends to occur at an earlier than average age, individuals may have more than one primary tumor, the tumors may be multicentric, usually more than 25 percent of the individuals in direct lineal descent from the proband are affected, and the cancer predisposition in these families behaves as an autosomal dominant trait with about 60 percent penetrance.
Intellectual Disability
Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)
Charcot-Marie-Tooth Disease
A hereditary motor and sensory neuropathy transmitted most often as an autosomal dominant trait and characterized by progressive distal wasting and loss of reflexes in the muscles of the legs (and occasionally involving the arms). Onset is usually in the second to fourth decade of life. This condition has been divided into two subtypes, hereditary motor and sensory neuropathy (HMSN) types I and II. HMSN I is associated with abnormal nerve conduction velocities and nerve hypertrophy, features not seen in HMSN II. (Adams et al., Principles of Neurology, 6th ed, p1343)
Cohort Studies
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Software
Genetic Loci
Specific regions that are mapped within a GENOME. Genetic loci are usually identified with a shorthand notation that indicates the chromosome number and the position of a specific band along the P or Q arm of the chromosome where they are found. For example the locus 6p21 is found within band 21 of the P-arm of CHROMOSOME 6. Many well known genetic loci are also known by common names that are associated with a genetic function or HEREDITARY DISEASE.
Chromosomes, Human, Pair 21
Arabs
Eye Diseases, Hereditary
Chromosomes, Human, X
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Superimposed histologic and genetic mapping of chromosome 9 in progression of human urinary bladder neoplasia: implications for a genetic model of multistep urothelial carcinogenesis and early detection of urinary bladder cancer. (1/2355)
The evolution of alterations on chromosome 9, including the putative tumor suppressor genes mapped to the 9p21-22 region (the MTS genes), was studied in relation to the progression of human urinary bladder neoplasia by using whole organ superimposed histologic and genetic mapping in cystectomy specimens and was verified in urinary bladder tumors of various pathogenetic subsets with longterm follow-up. The applicability of chromosome 9 allelic losses as non-invasive markers of urothelial neoplasia was tested on voided urine and/or bladder washings of patients with urinary bladder cancer. Although sequential multiple hits in the MTS locus were documented in the development of intraurothelial precursor lesions, the MTS genes do not seem to represent a major target for p21-23 deletions in bladder cancer. Two additional tumor suppressor genes involved in bladder neoplasia located distally and proximally to the MTS locus within p22-23 and p11-13 regions respectively were identified. Several distinct putative tumor suppressor gene loci within the q12-13, q21-22, and q34 regions were identified on the q arm. In particular, the pericentromeric q12-13 area may contain the critical tumor suppressor gene or genes for the development of early urothelial neoplasia. Allelic losses of chromosome 9 were associated with expansion of the abnormal urothelial clone which frequently involved large areas of urinary bladder mucosa. These losses could be found in a high proportion of urothelial tumors and in voided urine or bladder washing samples of nearly all patients with urinary bladder carcinoma. (+info)Temporal and multiple quantitative trait loci analyses of resistance to bacterial wilt in tomato permit the resolution of linked loci. (2/2355)
Ralstonia solanacearum is a soil-borne bacterium that causes the serious disease known as bacterial wilt in many plant species. In tomato, several QTL controlling resistance have been found, but in different studies, markers spanning a large region of chromosome 6 showed strong association with the resistance. By using two different approaches to analyze the data from a field test F3 population, we show that at least two separate loci approximately 30 cM apart on this chromosome are most likely involved in the resistance. First, a temporal analysis of the progression of symptoms reveals a distal locus early in the development of the disease. As the disease progresses, the maximum LOD peak observed shifts toward the proximal end of the chromosome, obscuring the distal locus. Second, although classical interval mapping could only detect the presence of one locus, a statistical "two-QTL model" test, specifically adapted for the resolution of linked QTL, strongly supported the hypothesis for the presence of two loci. These results are discussed in the context of current molecular knowledge about disease resistance genes on chromosome 6 and observations made by tomato breeders during the production of bacterial wilt-resistant varieties. (+info)Homozygosity mapping to the USH2A locus in two isolated populations. (3/2355)
Usher syndrome is a group of autosomal recessive disorders characterised by progressive visual loss from retinitis pigmentosa and moderate to severe sensorineural hearing loss. Usher syndrome is estimated to account for 6-10% of all congenital sensorineural hearing loss. A gene locus in Usher type II (USH2) families has been assigned to a small region on chromosome 1q41 called the UHS2A locus. We have investigated two families with Usher syndrome from different isolated populations. One family is a Norwegian Saami family and the second family is from the Cayman Islands. They both come from relatively isolated populations and are inbred families suitable for linkage analysis. A lod score of 3.09 and 7.65 at zero recombination was reached respectively in the two families with two point linkage analysis to the USH2A locus on 1q41. Additional homozygosity mapping of the affected subjects concluded with a candidate region of 6.1 Mb. This region spans the previously published candidate region in USH2A. Our study emphasises that the mapped gene for USH2 is also involved in patients from other populations and will have implications for future mutation analysis once the USH2A gene is cloned. (+info)Genetics of the SCA6 gene in a large family segregating an autosomal dominant "pure" cerebellar ataxia. (4/2355)
Spinocerebellar ataxia type 6 (SCA6) is an autosomal dominant cerebellar degeneration caused by the expansion of a CAG trinucleotide repeat in the CACNA1A gene. Mutations in patients are characterised by expanded alleles of between 21 and 30 repeat units and by extreme gonadal stability when transmitted from parents to children. We have investigated the SCA6 mutation in a large Spanish kindred in which previously reported spinocerebellar SCA genes and loci had been excluded. We observed a 23 CAG repeat expanded allele in the 13 clinically affected subjects and in three out of 10 presymptomatic at risk subjects. Transmission of the mutant allele was stable in six parent to child pairs and in 29 meioses through the pedigree. Linkage analysis with the SCA6-CAG polymorphism and marker D19S221 confirmed the location of SCA6 on chromosome 19p13. The molecular findings in this large family confirm the expansion of the CAG repeat in the CACNA1A gene as the cause of SCA6 and the high meiotic stability of the repeat. (+info)Evidence that mutations in the X-linked DDP gene cause incompletely penetrant and variable skewed X inactivation. (5/2355)
X chromosome inactivation results in the random transcriptional silencing of one of the two X chromosomes early in female development. After random inactivation, certain deleterious X-linked mutations can create a selective disadvantage for cells in which the mutation is on the active X chromosome, leading to X inactivation patterns with the mutation on the inactive X chromosome in nearly 100% of the individual's cells. In contrast to the homogeneous patterns of complete skewed inactivation noted for many X-linked disorders, here we describe a family segregating a mutation in the dystonia-deafness peptide (DDP) gene, in which female carriers show incompletely penetrant and variable X inactivation patterns in peripheral blood leukocytes, ranging between 50:50 and >95:5. To address the genetic basis for the unusual pattern of skewing in this family, we first mapped the locus responsible for the variable skewing to the proximal long arm (Xq12-q22) of the X chromosome (Z=5. 7, P=.002, LOD score 3.57), a region that includes both the DDP and the XIST genes. Examination of multiple cell types from women carrying a DDP mutation and of peripheral blood leukocytes from women from two unrelated families who carry different mutations in the DDP gene suggests that the skewed X inactivation is the result of selection against cells containing the mutant DDP gene on the active X chromosome, although skewing is apparently not as severe as that seen for many other deleterious X-linked mutations. Thus, DDP is an example of an X-linked gene for which mutations cause partial cell selection and thus incompletely skewed X inactivation in peripheral blood leukocytes. (+info)Location score and haplotype analyses of the locus for autosomal recessive spastic ataxia of Charlevoix-Saguenay, in chromosome region 13q11. (6/2355)
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a clinically homogeneous form of early-onset familial spastic ataxia with prominent myelinated retinal nerve fibers. More than 300 patients have been identified, and most of their families originated in the Charlevoix-Saguenay region of northeastern Quebec, where the carrier prevalence has been estimated to be 1/22. Consistent with the hypothesis of a founder effect, we observed excess shared homozygosity at 13q11, among patients in a genomewide scan of 12 families. Analysis of 19 pedigrees demonstrated very tight linkage between the ARSACS locus and an intragenic polymorphism of the gamma-sarcoglycan (SGCG) gene, but genomic DNA sequence analysis of all eight exons of SGCG revealed no disease-causing mutation. On the basis of haplotypes composed of seven marker loci that spanned 11.1 cM, the most likely position of the ARSACS locus was 0.42 cM distal to the SGCG polymorphism. Two groups of ARSACS-associated haplotypes were identified: a large group that carries a common SGCG allele and a small group that carries a rare SGCG allele. The haplotype groups do not appear to be closely related. Therefore, although chromosomes within each haplotype group may harbor a single ARSACS mutation identical by descent, the two mutations could have independent origins. (+info)Evidence for a rare prostate cancer-susceptibility locus at chromosome 1p36. (7/2355)
Combining data from a genomic screen in 70 families with a high risk for prostate cancer (PC) with data from candidate-region mapping in these families and an additional 71 families, we have localized a potential hereditary PC-susceptibility locus to chromosome 1p36. Because an excess of cases of primary brain cancer (BC) have been observed in some studies of families with a high risk for PC, and because loss of heterozygosity at 1p36 is frequently observed in BC, we further evaluated 12 families with both a history of PC and a blood relative with primary BC. The overall LOD score in these 12 families was 3.22 at a recombination fraction (theta) of .06, with marker D1S507. On the basis of an a priori hypothesis, this group was stratified by age at diagnosis of PC. In the younger age group (mean age at diagnosis <66 years), a maximum two-point LOD score of 3.65 at straight theta = .0 was observed, with D1S407. This linkage was rejected in both early- and late-onset families without a history of BC (LOD scores -7.12 and -6.03, respectively, at straight theta = .0). After exclusion of 3 of the 12 families that had better evidence of linkage to previously described PC-susceptibility loci, linkage to the 1p36 region was suggested by a two-point LOD score of 4.74 at straight theta = .0, with marker D1S407. We conclude that a significant proportion of these families with both a high risk for PC and a family member with BC show linkage to the 1p36 region. (+info)Autosomal dominant myopathy with proximal weakness and early respiratory muscle involvement maps to chromosome 2q. (8/2355)
Two Swedish families with autosomal dominant myopathy, who also had proximal weakness, early respiratory failure, and characteristic cytoplasmic bodies in the affected muscle biopsies, were screened for linkage by means of the human genome screening set (Cooperative Human Linkage Center Human Screening Set/Weber version 6). Most chromosome regions were completely excluded by linkage analysis (LOD score <-2). Linkage to the chromosomal region 2q24-q31 was established. A maximum combined two-point LOD score of 4.87 at a recombination fraction of 0 was obtained with marker D2S1245. Haplotype analysis indicated that the gene responsible for the disease is likely to be located in the 17-cM region between markers D2S2384 and D2S364. The affected individuals from these two families share an identical haplotype, which suggests a common origin. (+info)
Evidence for a rare prostate cancer-susceptibility locus at chromosome 1p36. In Swedish families with hereditary prostate...
Willoughby, Mol Vis 2005; 11:587-593. Table 2.
A genome-wide scan for loci affecting normal adult height in the Framingham Heart Study
Published Articles
BDgene Database
A genome-scan in a single pedigree with a high prevalence of multiple sclerosis | Journal of Neurology, Neurosurgery &...
An extension of the Maximum Lod Score method to X-linked loci. - Oxford Cardiovascular Science
What is a LOD Score? (with pictures)
Plus it
ADHDgene Database
Interactive graphics for high-dimensional genetic data
April | 2017 | immune-source.com
Ultimate Guide to Level of Detail or LOD in Tableau
Driver Controlled lod bias » найден
rapidmicrobiology » Study Shows FecalSwab™ Improved LOD for Enteric Pathogens
Abstracts
Claas Ares
Are there any advantages if you score 8.5 in the IELTS? 万象客
Musescore crashing at first attempted edit after opening larger concert band score | MuseScore
Nance-Horan Syndrome: Localization within the region Xp21.1-Xp22.3 by linkage analysis<...
Follow-up of Genetic Linkage Findings on Chromosome 16p13: Evidence of Association of N-methyl-D Aspartate Glutamate Receptor...
Genome wide scan in a Flemish inflammatory bowel disease population: support for the IBD4 locus, population heterogeneity, and...
Rabbit polyclonal to GLUT1 - BET-bromodomain inhibition research
DSpace at KOASAS: Canine polydactyl mutation associated with C7orf2/Lmbr1 gene = C7orf2/Lmbr1 유전자와 관련된 개의 다지증 돌연변이
Mutations in FN1 cause glomerulopathy with fibronectin deposits | PNAS
Parametric analysis of impact configurations in crutch walking
Evidence of linkage to chromosome 9q22.33 in colorectal cancer kindreds from the United Kingdom. - Nuffield Department of...
Pooled genome-wide linkage data on 424 ADHD ASPs suggests genetic heterogeneity and a common risk locus at 5p13 | Molecular...
Genomewide linkage analysis of age of onset of Huntingtons disease - Oxford Neuroscience
BDgene Database
Plus it
Gentaur Molecular :Wanger \ Kanamycin ELISA kit Sensitivity 0.5ng ml, LOD 0.5-40.5ng ml, Temperature 25℃, Sample vaccine \ HA176
Gentaur Molecular :Wanger \ Clenbuterol 40 Tests LOD 5ppb Samples animal tissue \ HB002
Which of the following complexes show linkage isomerism?
Browsing 2010 fascicula8 nr1 by Subject initial deformations
Linkage Analysis In Psychiatric Disorders
Detecting Gene‐Gene Interaction in Linkage Analysis - Current Protocols
TYPOLOGY OF EMPIRICAL ATTRIBUTES. DISSIMILARITY LINKAGE ANALYSIS (DLA).
Persönlichkeit und Kommunikation: authentisch bewusst erfolgreich - PCM® Basisseminar Teil 2 - key!4c
Email this page ( Why wont LOD RADIUS stick? ) - The AVSIM Community
SIKU Blister - aut ko Wiesmann GT - Siku Auta, letadla, lod | CZHra ky
SIKU Blister - Vesm rn raketopl n - Auta, letadla, lod | OK Hra ky
Ande Gyöngy: Hering hernyó :)
Some scores not showing properly in Score View (related to undo and page size?) | MuseScore
Posterior polar cataract legal definition of posterior polar cataract
Microsatellite association mapping of a primary osteoarthritis susceptibility locus on chromosome 6p12.3-q13. - The Kennedy...
Leicester Research Archive: Two-dimensional genome-scan identifies novel epistatic loci for essential hypertension.
Meta-analysis of five genome-wide linkage studies for body mass index reveals significant evidence for linkage to chromosome 8p...
A genome-wide significant linkage for severe depression on chromosome 3:the depression network study - Lancaster EPrints
Multipoint quantitative-trait linkage analysis in general pedigrees
Type 2 diabetes: Evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs | PNAS
A genomewide linkage study of 1,933 families affected by premature coronary artery disease: The British Heart Foundation (BHF)...
A genome scan for serum triglyceride in obese nuclear families<...
Genome-wide linkage analysis of inherited hydrocephalus in the H-Tx rat, Mammalian Genome | 10.1007/s003350010226 | DeepDyve
Significant evidence of one or more susceptibility loci for endometriosis with near-Mendelian inheritance on chromosome 7p13-15...
Linkage study - Conservapedia
Localization of gene for familial hypertrophic cardiomyopathy to chromosome 14q1 in a diverse US population. | Circulation
Whole Brain and Regional Hyperintense White Matter Volume and Blood Pressure | Stroke
QIMR Genetic Epidemiology Laboratory Home Page
DSLINK: A computer program for gene-centromere linkage analysis in families with a trisomic offspring<...
Sex and age specific effects of chromosomal regions linked to body mass index in the Framingham Study | BMC Genomic Data | Full...
Sex and age specific effects of chromosomal regions linked to body mass index in the Framingham Study | BMC Genomic Data | Full...
Gene Hunters at Johns Hopkins Close In On Lou Gehrigs Disease ( In the first genomewide search for the ...)
DotA 6.78c LoD v2g Map Download - Legends of DotA | Dota-Utilities
DotA 6.78c LoD v2g Map Download - Legends of DotA | Dota-Utilities
Site | The Ohio Program
Showing results for tags amg. - TurboDuck.net
Agro-Ecosystem-wise Status of Technological Interventions Implemented under Institution-Village Linkage Programme (IVLP) in...
Nervenet.org
IWC | Archive
NITRC: CONN : functional connectivity toolbox: RE: Clarification on contrasts in CONN 2nd-level multivariate analysis
UWI Mona Research Engine [beta]
Whole-genome Scan Helps To Choose Best Treatment For Neuroblastoma
Examples of errors detected by the V768 diagnostic
asu.edu.jo
Zithromax Or Zmax - Order Zithromax - Cheap Drugs
FREE Pedigree Dentastix Dog Treats Sample • Guide2Free Samples
Pedigree Dogs Exposed: Three Years On
Pedigree Dogs Exposed: Three Years On
NVD - CVSS v3 Calculator
NVD - CVSS v3 Calculator
Robin Lod
Finland score listed first, score column indicates score after each Lod goal. Klubi 04 Kakkonen: 2011 HJK Helsinki ... "Lod, Robin". National Football Teams. Retrieved 27 August 2019. "R. Lod". Soccerway. Retrieved 27 August 2019. "Robin Lod". ... Robin Lod scored in his debut match in Spain, Petteri Forsell scored twice in the Polish league] (in Finnish). Yle. 27 August ... Lod scored his first goal on his senior debut for HJK on 22 October 2011 in a 4−1 home win against MYPA. During the 2012 season ...
Mega2, the Manipulation Environment for Genetic Analysis
Lathrop GM, Lalouel JM (1984). "Easy calculations of lod scores and genetic risks on small computers". Am J Hum Genet. 36 (2): ... Kong A, Cox NJ (1997). "Allele-sharing models: LOD scores and accurate linkage tests". Am J Hum Genet. 61 (5): 1179-1188. doi: ... Sobel E, Lange K (1996). "Descent graphs in pedigree analysis: Applications to haplotyping, location scores, and marker-sharing ...
Inclusive composite interval mapping
The test statistic LOD score linearly increases as the increase in population size. The larger of the QTL effect, the greater ... the corresponding LOD score increases. When population size is greater than 200, the position estimation of ICIM for QTL ...
Lod (disambiguation)
... see ΔT Limit of detection LOD score, logarithm of odds Loss on drying Level of Development or Level of Detail, in Building ... Lod is a city in Israel. Lod, LOD and LoD may also refer to: Legal Operations Detachment; see United States Army Reserve Legal ... a measurement of a ship over the deck from forward deck to the transom LOD, the length of a mean solar day in a uniform time ... in Italy Lod (crater), a crater in the Oxia Palus quadrangle of Mars Legacy of Darkness (disambiguation), multiple uses The ...
Disease gene identification
If one block of homozygosity is a result of a very non-diverse region of the genome, the LOD score will be very low). Tools for ... This can be accomplished by plotting a cumulative LOD score alongside the overlaid blocks of homozygosity. By taking into ...
Xq28
The study confirmed the Xq28 linkage to homosexuality by two-point and multipoint (MERLIN) LOD score mapping. Significant ...
Ali Mohamed (footballer)
On 19 February 2016, he scored his first goal in a 3-2 victory against Bnei Lod. On 6 July, Mohamed signed a contract with ... On 17 March 2017, he scored his first goal for the club in a 4-0 win against Hapoel Katamon Jerusalem. Mohamed finished the ... he made his debut for the club in a 4-1 loss to Bnei Lod. ...
Biology and sexual orientation
The data strongly replicated Hamer's Xq28 findings as determined by both two-point and multipoint (MERLIN) LOD score mapping. ...
Genetic linkage
... a LOD score for each estimate The estimate with the highest LOD score will be considered the best estimate The LOD score is ... Positive LOD scores favour the presence of linkage, whereas negative LOD scores indicate that linkage is less likely. ... a LOD score less than −2.0 is considered evidence to exclude linkage. Although it is very unlikely that a LOD score of 3 would ... the mathematical properties of the test allow data from a number of pedigrees to be combined by summing their LOD scores. A LOD ...
Protein methods
By analyzing DNA alleles can be identified as being associated with disease states, such as in calculation of LOD scores. ...
Murad Alyan
His prolific scoring at the lower levels of the Israeli League, prompted his former team, Hapoel Bnei Lod, now in Liga Artzit ... In the 2003-04 season, Alyan joined Bnei Lod and helped them win Liga Bet by scoring 24 goals, a team high. The next season, he ... He scored 15 goals in his first season and finished as the West Bank Premier League top scorer. In his second season, he again ... Scores and results list the Palestine's goal tally first. Best Palestinian Player: 2011 "مراد عليان من طفل مدلل الى جزار لا ...
Blau syndrome
A marker, D16S298, gave a maximum logarithm of odds (LOD) score of 3.75 and put the BS susceptibility locus within the 16p12- ...
Family-based QTL mapping
... the traditional lod score model), weakly model based (variance components methods), or model free. Variance component methods ...
Martín Rose
He played forty-one games and scored eight. In 2018, Rose joined Liga Leumit side Hapoel Bnei Lod. He made just three ... who he scored against in a 1-2 defeat on 5 October. Rose returned to Argentina with former team Los Andes, now of Primera B ... Hapoel Bnei Lod F.C. players, Sportspeople from Buenos Aires Province, All stub articles, Argentine football midfielder, 1990s ...
Dean Hamer
... with over 300,000 single-nucleotide polymorphism markers confirmed the Xq28 linkage by two-point and multipoint LOD score ...
2014-15 Toto Cup Leumit
The final was played at the Ramat Gan Stadium on 9 December 2014, which saw Hapoel Bnei Lod defeat Bnei Yehuda with a score of ... Lod v Beitar Tel Aviv Ramla Ironi Tiberias v Hapoel Bnei Lod Maccabi Kiryat Gat v Bnei Yehuda Bnei Yehuda v Hapoel Bnei Lod ... Superior goal difference Higher number of victories achieved Higher number of goals scored Higher number of points obtained in ... 4th goals scored; 5th head-to-head; 6th decision match (A) Advanced to the quarterfinals Source: football.org.il (in Hebrew) ...
Glossary of genetics (0-L)
LOD score long arm In condensed chromosomes where the positioning of the centromere creates two segments or "arms" of unequal ... The returned list is arranged by a similarity score indicating the percentage of the query sequence that is present exactly as ...
Glossary of genetics
LOD score long arm In condensed chromosomes where the positioning of the centromere creates two segments or "arms" of unequal ...
Dermatopathia pigmentosa reticularis
... linkage analysis of the combined genotyping data for three families across the NFJS/DPR candidate region generated an LOD score ... of 6.2 at marker D17S800, with a recombination score of 0. Further analysis revealed that NFJS may be caused by an identical ...
Outline of genetics
... karyotype knockout leukemia List of human genetic disorders locus LOD score lymphocyte malformation Gene mapping marker ...
Neurogenetics
Early analysis relied on statistical interpretation through processes such as LOD (logarithm of odds) scores of pedigrees and ... Logarithm of odds (LOD) is a statistical technique used to estimate the probability of gene linkage between traits. LOD is ...
2018-19 Sporting de Gijón season
... and Pablo Fernández scored the two goals. On 23 July, the club signed Finnish international winger Robin Lod for two seasons. ... and Real Sporting defeated Gimnàstic by 2-0 with goals of Hernán Santana and Robin Lod, both players scoring for the first time ... Robin Lod, called up for playing the UEFA Nations League with Finland, missed the game. Rubén Baraja and the rest of the ... "Robin Lod ya está en Gijon para fichar por el Sporting". La Voz de Asturias (in European Spanish). 2018-07-23. Retrieved 2018- ...
Infantile convulsions and choreoathetosis
... with a maximum lod score, for D16S3133 of 6.76 at a recombination fraction of 0. The disease gene has been mapped at chromosome ...
Genetics of synesthesia
Using the LOD score which describes the likelihood that two genes are near each other on a chromosome, and thus will be ... The area with the highest LOD score in the genome of an individual with auditory-visual synesthesia has been shown to be linked ...
Quantitative trait locus
In interval mapping, each locus is considered one at a time and the logarithm of the odds ratio (LOD score) is calculated for ...
List of MeSH codes (G13)
... lod score MeSH G13.695.450 - genetic markers MeSH G13.695.650 - penetrance MeSH G13.700.131 - aneuploidy MeSH G13.700.131.500 ...
Index of genetics articles
Linear tetrad Linkage Linkage analysis Linkage equilibrium Linkage group Linkage map Linking number Locus Lod score Lod score ...
Linda M. Brzustowicz
... "a major schizophrenia susceptibility locus on chromosome 1q21-22 with a multipoint lod score of 6.50 (p. ...
Index of molecular biology articles
LOD score - lymphocyte - M13 phage - malformation - mapping - marker - melanoma - melting - Johann Mendel - Mendelian ...
Khalil Lambin
He moved to Israel in 2014, playing first for Hapoel Bnei Lod and then for Maccabi Yavne in the 2014-15 Liga Leumit. He scored ... Hapoel Bnei Lod Toto Cup: 2014-15 "KHALLIL: "Il y a beaucoup de manière différente de recevoir la gloire dans ce monde"". ... He played seven games in the league, and scored a goal in six games in the 2012 AFC Cup. In summer 2012, Lambin signed for ... Lambin signed for Belgian First Division B side Patro Eisden in 2015, where he scored six goals in 24 games, before joining ...
List of Israel State Cup winners
The 1932 final was abandoned with the score 1-0 to Hapoel Haifa, when the Haifa club's players walked off the field in protest ... Two small-town clubs, Hapoel Yehud and Hapoel Lod, won the cup for the first time in 1982 and 1984 respectively, but otherwise ...
829 Naval Air Squadron
During the Battle of Matapan, late in March, one of the squadron's Albacores scored a hit on the Italian battleship Vittorio ... after which the aircraft operated from Lod for some time, attacking Vichy French shipping during the Syria-Lebanon campaign. ... scoring hits. Santa Fe was damaged badly enough to prevent her from submerging. The crew abandoned the submarine at the jetty ...
November 1965
Lod and Ramla) having boards of between five and seven Muslim residents to control the lands within the restrictions of the Tel ... Scores Hurt", Chicago Tribune, November 25, 1965, p1 "Gas Reported Blast Cause; Toll Set at 7- 47 Injured in Iowa Armory ...
2014-15 Liga Leumit
Hapoel Afula Maccabi Herzliya Hapoel Jerusalem Hapoel Kfar Saba Maccabi Kiryat Gat Hapoel Bnei Lod M. Ahi Nazareth H. Nazareth ... Notes: The match originally was abandoned after supporter violence while the score was 1-1. The Israel Football Association ... 4th goals scored; 5th head-to-head; 6th decision match. Winners of 2014-15 Israel State Cup qualify for the second qualifying ... 4th goals scored; 5th head-to-head; 6th decision match (O) Play-off winner; (R) Relegated Source: Israel Football Association ...
Langkær Gymnasium & HF
IB graduates from Langkaer Gymnasium achieved high diploma scores, some received places at prestigious international ... Da Langkaer Gymnasium lod sig sluge". Gymnasieskolernes Lederforening (in Danish).{{cite web}}: CS1 maint: url-status (link) " ...
Israel women's national football team
Lod Attendance: 100 Referee: Ivana Martinčić (Croatia) 25 October 2015 (2015-10-25) 18:00 Lod Municipal Stadium, Lod Attendance ... "Live Scores - Wales - Women's - Matches - FIFA.com". FIFA.com. Archived from the original on April 20, 2016. uefa.com. "Women's ... As of April 2015, the national team played 95 matches (31 wins, 7 draws, 57 losses), scoring 111 goals. The team is yet to make ... Standings Source: UEFA Rules for classification: Qualification tiebreakers Matches 22 October 2015 (2015-10-22) 18:00 Lod ...
Emil Hartmann
1896 Free scores by Emil Hartmann at the International Music Score Library Project (IMSLP) Biography at naxos.com (Articles ... Det store Lod (Comic Opera after Henrik Hertz, 1898) By Summertime (Ved Sommertiden, Cantata for Chorus and Orchestra) Rinaldo ... Articles with International Music Score Library Project links, Articles with ISNI identifiers, Articles with VIAF identifiers, ...
Miroslav Antonov
He scored 15 goals in 29 matches. In the first half of the next season he earned 15 appearances playing in the A PFG, scoring ... Hapoel Bnei Lod F.C. players, Hapoel Nir Ramat HaSharon F.C. players, Aiolikos F.C. players, First Professional Football League ... On 10 February 2010, Antonov scored his first goal for Levski in the 1:0 win against Belarusian side Dinamo Minsk in a friendly ...
Anas Dabour
On 29 May 2009 he made his debut at the first team 2-4 loss to Hapoel Bnei Lod. During the 2012/13 scoring 8 league goals was ... Hapoel Bnei Lod F.C. players, Hapoel Iksal F.C. players, Hapoel Rishon LeZion F.C. players, Liga Leumit players, Israeli ...
Idan Shriki
On January 16, 2013, he was loaned to Maccabi Petah Tikva after a very poor half season with Netanya where he only scored 2 ... Hapoel Bnei Lod F.C. players, Hapoel Marmorek F.C. players, Hapoel Ashdod F.C. players, Israeli Premier League players, Liga ... Playing behind Yaniv Azran and Shay Holtzman, the threesome accounted for 77% of goals scored by Ashdod. In July 2011, Shriki ... he was released from his contract with Netanya and moved to Maccabi Kiryat Gat there he had a rather poor season only scoring 5 ...
Boaz Kofman
During his Time with the club, Kofman scored 121 league goals and 29 cup goals, including scoring in three cup finals. After ... Kofman started his coaching career with stints as player-manager at Sektzia Ness Ziona and Beitar Lod, and, after retiring from ... Kofman played a total of 8 matches for the national team, scoring one goal, against Cyprus, in 1960. ... after a season at Beitar Lod, where he served as player-manager. In 1956, Kofman made his debut for Israel, in an Olympic ...
Yakuza 3
Latest Famitsu review scores, Nintendo Everything Hoggins, Tom (March 29, 2010). "Yakuza 3 video game review". The Daily ... In addition, the PlayStation 3 employs advanced graphics technologies without LOD, texture size 512×512 front buffer with 512× ...
Ahmed Harbi
He scored his first goal for the national team against Myanmar in the final game of 2012 AFC Challenge Cup qualifying. He was ... Hapoel Bnei Lod F.C. players, Ahli Al-Khaleel players, Shabab Al-Dhahiriya SC players, Liga Leumit players, West Bank Premier ...
Elyaniv Barda
Barda scored three times in 17 matches for the Israel U21 team between 2001 and 2003. On 17 November 2007, he scored the ... Elyaniv's younger brother Yinon is also a striker who plays for Hapoel Bnei Lod. (correct as of 9 July 2015) Maccabi Haifa Toto ... Barda played 62 matches for Hapoel Tel Aviv, scoring on 17 occasions. He also scored 3 goals in Hapoel's successful 2006-07 ... He had earlier failed to agree a move to Cypriot club APOEL F.C. In his first season at Genk in 2007/08, he scored 16 goals in ...
Roman mosaic
As-Suwayda, Syria Mosaic of Amazon warrior engaged in combat with a hippeus, 4th century AD, Louvre Ancient Rome portal Lod ... Traces of guidelines have been found beneath some mosaics, either scored into or painted onto the mortar bedding. The design ... Mosaics of Roman Britain Association for the Study and Preservation of Roman Mosaics Discovery of Roman mosaic in Lod, Israel ...
Fleischer Studios
The score was by Paramount staff composer, Victor Young and recorded at the Paramount west coast facilities. While limited to ... Steve Muffati Grim Natwick Bill Nolan Joe Oriolo Sid Pillet Graham Place Lod Rossner Ted Sears Hal Seeger Gordon Sheehan Ben ...
Salim Tuama
He scored the winning goal in a 1-0 victory over newly crowned champions Maccabi Haifa in the Israeli State Cup final of 2010- ... Tuama has lived his life in the city of Lod, but began his career using the facilities of the Gadna club due to the poor ... He signed for Greek side Larissa and spent one season there, scoring two goals. At the end of the 2009-10 season, Tuama ... His former clubs include Hapoel Tel Aviv, Standard Liège, Maccabi Petah Tikva, Kayserispor, Larissa, Hapoel Bnei Lod and the ...
Palestinian political violence
"Sympathy for terrorism" was found to be correlated with depression and anxiety scores, as well as with the level of "perceived ... Lauro Jaffa Road bus bombings Jerusalem bus 19 suicide bombing Karkur junction suicide bombing Kiryat Menachem bus bombing Lod ...
December 1988
... the NC State Wolfpack defeat the Iowa Hawkeyes by a score of 28-23. The Chicago Bears defeat the Philadelphia Eagles by a score ... The plane lands at a military airstrip near Ben Gurion Airport in Lod, Israel, where the hijackers surrender. Yitzhak Rabin, ... In the 1988 Sun Bowl, played at the Sun Bowl in El Paso, Texas, the Alabama Crimson Tide defeat the Army Cadets by a score of ... the Washington State Cougars defeat the Houston Cougars by a score of 24-22. On Christmas night, an Amtrak train derails in ...
History of Palestine
were witnessing the foundations of scores if not hundreds of insignificant and unprotected village settlements, not least in ... near Lod). The period also saw the construction of many schools and the renovation of mosques neglected or destroyed during the ... At Antioch and at Emesa he scored a decisive victory against the Palmyrene army and in 272 he forced Palmyra to surrender ( ...
Ahmad Saba'a
In August 2003 he moved to Hapoel Bnei Lod. He helped Lod win two promotions, the first came in the 2004-05 season when the ... On 4 November 2012 he became the first to score a goal in the opening game of the new Netanya Stadium as Netanya won the game 2 ... In 4 seasons with the club Saba'a scored 62 goals in a total of 153 games in all club competitions. Saba'a is in the top ten ... In 6 seasons with the club Saba'a scored 61 goals in 149 league games. On 20 January 2009, Saba'a signed a one-year deal with ...
Ria Öling
She scored her first senior international goal on the occasion of her fifth cap, in a 1-0 UEFA Women's Euro 2017 qualifying win ... "Lod ja Öling parhaat liigapelaajat - myös Platinille palkinto" (in Finnish). Helsingin Sanomat. 30 October 2014. Retrieved 17 ...
2019-20 Hapoel Haifa F.C. season
Goals scored; 5) Head-to-head points; 6) Head-to-head goal difference; 7) Head-to-head goals scored; 8) Play-off. (C) Champion ... Notes: Qualified due to winning the 2019-20 Israel State Cup Win Draw Loss Hapoel Bnei Lod v Hapoel Haifa Hapoel Haifa v Kafr ... Source: Soccerway Rules for classification: 1) Points; 2) Goal difference; 3) Matches won; 4) Goals scored; 5) Head-to-head ... goals scored; 5) head to head; 6)deciding match. Maccabi Netanya v Hapoel Haifa Hapoel Haifa v Hapoel Ironi Kiryat Shmona ...
Tel Aviv
Located in the neighbouring city of Lod, it handled over 20 million passengers in 2017. Ben Gurion is the main hub of El Al, ... "USATODAY.com - Six killed, scores wounded in suicide attack on Tel Aviv bus". USA Today. McLean, VA. 19 September 2002. ISSN ...
Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa | PLOS Genetics
Two- point LOD scores of fine mapping markers.. Autosomal recessive retinitis pigmentosa was analyzed as a fully penetrant ... Easy calculations of lod scores and genetic risks on small computers. American Journal of Human Genetics. 1984;36:460-5. pmid: ... producing maximum LOD scores of 8.9, 5.0, 3.86, 2.44, and 2.45 at θ = 0 (with the CLCC1 variant), respectively (S1 Table). All ... Improving the assessment of the outcome of nonsynonymous SNVs with a consensus deleteriousness score, Condel. Am J Hum Genet. ...
A human cell-surface receptor for xenotropic and polytropic murine leukemia viruses: possible role in G protein-coupled signal...
Two-locus maximum lod score analysis of a multifactorial trait: joint consideration of IDDM2 and IDDM4 with IDDM1 in type 1...
Here, we present an extension of the maximum lod score method of N. Risch, which allows the simultaneous detection and modeling ... Two-locus maximum lod score analysis of a multifactorial trait: joint consideration of IDDM2 and IDDM4 with IDDM1 in type 1 ... Two-locus maximum lod score analysis of a multifactorial trait: joint consideration of IDDM2 and IDDM4 with IDDM1 in type 1 ... Here, we present an extension of the maximum lod score method of N. Risch, which allows the simultaneous detection and modeling ...
Talking Glossary of Genetic Terms | NHGRI
LOD Score. An LOD (short for "logarithm of the odds") score is a statistical estimate of the relative probability that two loci ... Polygenic Risk Score (PRS). A polygenic risk score (abbreviated PRS) uses genomic information alone to assess a persons ... A genotype is a scoring of the type of variant present at a given location (i.e., a locus) in the genome. It can be represented ...
PDF) A De Novo Chromosome-Level Genome Assembly of the White-Tailed Deer, Odocoileus Virginianus
Allele-sharing models: LOD scores and accu-. rate linkage tests. Am J Hum Genet. 61:1179-1188. ... of 508 scaffolds with a contig N50 of 21.7 Mb, a scaffold N50 of 52.4Mb, and a BUSCO complete score of 93.1%. Thirty-six ... broader and deeper phylogenetic coverage for scoring of eukary-. otic, prokaryotic, and viral genomes. Mol Biol Evol. 38:4647- ... BUSCO Update: Novel and Streamlined Workflows along with Broader and Deeper Phylogenetic Coverage for Scoring of Eukaryotic, ...
Autoimmune Polyglandular Disease Type I | European Journal of Human Genetics
... the expected lod score at a recombination fraction of 0.01 ranges from 4.262 to 9.958 (95% confidence interval). The lod score ... The corresponding maximal lod score achieved in multipoint (LINK-MAP) analysis with the disease against the three markers of ... This apparent numeric discrepancy is due to the nature of the EXCLUDE program in which the obtained lod scores are not ... The total length of the chromosomal regions revealing a relative exclusion (lod score ,-1.0) was 1,597.7 cM (table 1) compared ...
Aiden Eliot Shearer, M.D. | Harvard Catalyst Profiles | Harvard Catalyst
Alc32 QTL Report (Rattus norvegicus) - Rat Genome Database
Exclusion of PTEN and 10q22-24 As the Susceptibility Locus for Juvenile Polyposis Syndrome1 | Cancer Research | American...
Mapping of a new locus for autosomal recessive non-syndromic mental retardation in the chromosomal region 19p13.12-p13.2:...
For lod score calculations, the number of alleles was set as the number observed in the pedigree, rather than the number ... We also thank Dr G Halpern for her help with editing the manuscript and Dr Tami Shohat for her help with the lod score ... Statistical analysis provided strong evidence for linkage of NSMR to chromosome 19p13.12-p13.2 with the maximal lod score of ... in order to provide a conservative estimate of the lod score. ...
A genome wide scan for early onset primary hypertension in Scandinavians. - Nuffield Department of Population Health
Publication : USDA ARS
Genetics of autistic disorders: review and clinical implications | SpringerLink
Autosomal dominant paroxysmal kinesigenic choreoathetosis: a clinical and genetic study of two families | Journal of Neurology,...
Genetic refinement and physical mapping of a 2.3 Mb probable disease region associated with a bipolar affective disorder...
Several other markers in the region gave LOD scores greater than 1.5. Non-parametric analysis provided additional support for ... with a maximum two-point LOD score of 3.2 for marker D4S1652. ... Several other markers in the region gave LOD scores greater ... with a maximum two-point LOD score of 3.2 for marker D4S1652. ...
Turkish Journal of Fisheries and Aquatic Sciences
Publications | Max Planck Institute
Regions on six chromosomes (4, 7, 10, 16, 19 and 22) were identified which generated a multipoint maximum lod score (MLS) > 1. ... maximum lod score = 6.62 at theta = 0.0), confirming autosomal dominant inheritance with full penetrance. Further analysis of ... we found linkage to schizophrenia for paternal sharing with LOD=4.72, P=0.0000016, within 3 cM of the peak linkage to relative ... along the lengths of all their chromosomes and attempting to correlate this similarity with that of their phenotypic scores. We ...
Naegeli-Franceschetti-Jadassohn Syndrome: Background, Pathophysiology, Etiology
Zebrafish relatively relaxed mutants have a ryanodine receptor defect, show slow swimming and provide a model of multi-minicore...
Search results - ORA - Oxford University Research Archive
The Molecular Genetics of ADHD: A View From the IMAGE Project
Table 1 summarizes their main results and gives their highest LOD scores (a statistic that measures the evidence for linkage). ... In other words, within-pair differences for behavioral scores are more reliable than across-pair comparisons. This was ... DeFries JC, Fulker DW (1988), Multiple regression analysis of twin data: etiology of deviant scores versus individual ... and nonidentical co-twin trait scores to the population trait mean where twin probands are selected for extreme scores (DeFries ...
4D genetic networks reveal the genetic basis of metabolites and seed oil-related traits in 398 soybean RILs | Biotechnology for...
Issue: The American Journal of Human Genetics
Familial Mediterranean Fever - CAGS
Neuroscience2014 | Per session
A novel Refsum-like disorder that maps to chromosome 20 | Neurology
NTNU Open: Genetic studies of LRRK2 and PINK1 in Parkinson's disease
Douglas Vollrath's Profile | Stanford Profiles
... with a maximum LOD score of 5. 92 at a recombination fraction of .00 for marker D11S903 and a multipoint maximum LOD score of ... Association of a Primary Open-Angle Glaucoma Genetic Risk Score With Earlier Age at Diagnosis. JAMA ophthalmology Fan, B. J., ... Genetic risk scores (GRS) examine the cumulative genetic load by combining individual genetic variants into a single measure, ... Age at natural menopause genetic risk score in relation to age at natural menopause and primary open-angle glaucoma in a US- ...
Robin LodMultipoint LOD scoreLociLinkageLogarithmHLODOddsMaximumMarkersChromosomesThresholdMinnesota UnitedWrittenResultsPublicationGroupInputShotGoalStatusFileResultPostCardChromosomeMultipoint lod scoreChromosomesLocusLociPoint lod scoresNegative LOD scoresRecombination fractionPeak lodMarkerMarkers2022Luis amarillaSuggestiveEmpiricalGenomeHeterozygosityAlleleAnalysesEqualizer2017GeneLinkage groupFamilyFoundQuality score recalibrationParametricRobinCalculationsMajor LeagueGalaxyDiseaseSignificantHunouReflectsEvidence20192016DataFamiliesAnalysis
Robin Lod8
- Robin Lod scores in Minnesota United's 2-0 win over the Houston Dynamo. (espn.com)
- Robin Lod and Brent Kallman scored goals and Tyler Miller registered his sixth shutout of the season to lead Minnesota United to a 2-0 victory over the Houston Dynamo on Saturday night in Saint Paul, Minn. (espn.com)
- ST. PAUL, Minn. (AP) - Robin Lod scored a late goal and Minnesota United beat Seattle 1-0 on Sunday to end the Sounders' MLS-record 13-game unbeaten streak to open a season. (apnews.com)
- Notebook: Robin Lod gave a very Lovable performance last night for Adrian Heath and Co. (epluribusloonum.com)
- Last night Robin Lod gave Minnesota United the goal that nearly sent them into the Quarter-Finals on its own. (epluribusloonum.com)
- If you ask any of the people in our team, in the squad, they all know the qualities that Robin [Lod] has got. (epluribusloonum.com)
- But, I have no worries about Robin Lod. (epluribusloonum.com)
- Robin Lod himself was very happy to be able to score last night. (epluribusloonum.com)
Multipoint LOD score2
- The mutation segregates with disease (multipoint LOD score 2.41). (ntnu.no)
- Primary open-angle glaucoma segregated as an autosomal dominant trait, with the disease locus mapping to 7q35-q36 between markers D7S2442 and D7S483 with a multipoint lod score of 4.06. (elsevier.com)
Loci5
- Here, we present an extension of the maximum lod score method of N. Risch, which allows the simultaneous detection and modeling of two unlinked disease loci. (ox.ac.uk)
- Linkage analyses of 6 multiplex MSA families revealed several loci showing positive heterogeneity lod (HLOD) scores. (jnss.org)
- Probabilidad relativa total, expresada en una escala logarítmica, de que exista una relación de vinculación entre loci seleccionados. (bvsalud.org)
- Four candidate loci yielded the highest score of 2.66 (Additional file 1 ). (biomedcentral.com)
- This track shows approximate positions of quantitative trait loci based on reported peak LOD scores from Mouse Genome Informatics (MGI) at the Jackson Laboratory . (ucsc.edu)
Linkage9
- The evidence for linkage to 4q35 was strengthened in this larger cohort, with a maximum two-point LOD score of 3.2 for marker D4S1652. (garvan.org.au)
- In contrast, a highly significant linkage was detected with a number of markers located in the vicinity of the type I keratin gene cluster on band 17q21, with maximum 2-lod scores of 4.16 and 3.717 for the markers D17S1787 and D17S1886, respectively. (medscape.com)
- Table 1 summarizes their main results and gives their highest LOD scores (a statistic that measures the evidence for linkage). (psychiatrictimes.com)
- A common method to allow for only a fraction of linked pedigrees is to fit a mixture likelihood and then to test for linkage homogeneity, given linkage (admixture test), or to test for linkage while allowing for heterogeneity, using the heterogeneity LOD (HLOD) score. (elsevier.com)
- Therefore, linkage analysis carried out in the present study indicates that ARVC-6 (cumulative LOD score is equal to plus 1.203376 at θ is equal to 0.05) could be the locus harboring the mutated gene in two out of three families. (who.int)
- Linkage analysis of the pooled raw genotype data generated maximum LOD scores in the same regions as identified by GSMA. (ox.ac.uk)
- We analyzed the relationship between the family-specific nonparametric linkage (NPL) scores and family averages of the covariates of interest (severity for chromosome 9, IgM for chromosome 11, anti-CCP for chromosome 18) with the ordered-subset analysis (OSA), using the original OSA software [ 3 ] and the high-to-low covariate ordering. (biomedcentral.com)
- RESULTS: The authors identified genome-wide significant linkage to chromosome 3p25-26 when the diagnoses were restricted by severity, which was a maximum LOD score of 4.0 centered at the linkage marker D3S1515. (lancs.ac.uk)
- Linkage analysis for calculating multipoint logarithm of the odds (LOD) scores was performed with Allegro using SNPs at intervals of 0.07 cM and sets of 100, and assuming recessive inheritance and a disease allele frequency of 0.001. (biomedcentral.com)
Logarithm1
- were ranging from 11.9% to 15.4% and the threshold of logarithm of odds (LOD) score is 3. (trjfas.org)
HLOD1
- Pedigree features are often used to create homogeneous subsets, and LOD or HLOD scores are then computed within the subsets. (elsevier.com)
Odds3
- This score is the log odds of being a true variant versus being false under the trained Gaussian mixture model. (broadinstitute.org)
- Lod es un acrónimo de ""logarithmic odds"", logaritmo de probabilidades. (bvsalud.org)
- Lod is an acronym for "logarithmic odds. (bvsalud.org)
Maximum5
- Two-locus maximum lod score analysis of a multifactorial trait: joint consideration of IDDM2 and IDDM4 with IDDM1 in type 1 diabetes. (ox.ac.uk)
- The most significant and consistent QTL across screening environments was located on chromosome 3BL, inherited from Sunco, with maximum LOD scores of 22 and 9 explaining 36% and 23% of the variation, respectively for the Sunco/Macon and Sunco/Otis populations. (usda.gov)
- We mapped the disease to a 15.96 Mb region on chromosome 20 (20p11.21-q12), containing approximately 200 genes (maximum lod score = 6.3). (neurology.org)
- Our strongest results are for chromosome 20, where we observe a weighted maximum LOD score (MLS) of 2.15 at map position 69.5 cM from pter and secondary weighted LOD-score peaks of 2.04 at 56.5 cM and 1.99 at 17.5 cM. (stroudcenter.org)
- A maximum LOD score of 8.12 at recombination fraction .00 was obtained with the microsatellite D10S588. (elsevier.com)
Markers1
- Several other markers in the region gave LOD scores greater than 1.5. (garvan.org.au)
Chromosomes1
- Five significant QTL were identified on chromosomes 3B, 4B, 4A, and 7A with LOD scores ranging from 3 to 22. (usda.gov)
Threshold1
- LOD score to be used as the threshold for clustering. (broadinstitute.org)
Minnesota United5
- ST. PAUL, Minn. (AP) - Cristian Arango scored for the third consecutive game and Jamal Blackman had a career-high seven saves and Los Angeles FC tied 1-1 with Minnesota United on Saturday night. (apnews.com)
- LOS ANGELES (AP) - Hassani Dotson scored in the fifth minute of stoppage time to give Minnesota United a 2-2 tie with with Los Angeles FC on Wednesday night. (apnews.com)
- ST. PAUL, Minn. (AP) - Chase Gasper scored once and Minnesota United secured a 2-1 win over the Portland Timbers on Saturday. (apnews.com)
- SANDY, Utah (AP) - Niko Hansen scored his first goal of the season to help Minnesota United tie Real Salt Lake 1-1 on Saturday night. (apnews.com)
- ST. PAUL, Minn. (AP) - Ramón Ábila scored his first MLS goal and Minnesota United beat the Vancouver Whitecaps 1-0 on Wednesday night for their first victory of the season. (apnews.com)
Written2
- This is a "connection" page, showing publications Michael H. Davidson has written about Lod Score. (uchicago.edu)
- Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author. (uchicago.edu)
Results2
- Clusters the results from a {@link CrosscheckFingerprints} run according to the LOD score. (broadinstitute.org)
- The wail that emerges when the game literally slips out of hands, slides to the floor, and results in grave loss of score will be sheer delight for you. (poochpickles.blog)
Publication1
- The connection strength for concepts is the sum of the scores for each matching publication. (uchicago.edu)
Group1
- Groups that do not have high LOD scores with any other group (including itself! (broadinstitute.org)
Input1
- The first pass consists of building a model that describes how variant annotation values co-vary with the truthfulness of variant calls in a training set, and then scoring all input variants according to the model. (broadinstitute.org)
Shot3
- The score came after midfielder Wil Trapp blasted a 25-yard shot from outside the box that handcuffed Maric. (espn.com)
- The goalie coughed up a rebound straight out to the onrushing Lod, who easily tapped in a left-footed shot inside the left post. (espn.com)
- Hansen, a 26-year-old midfielder who made his first appearance for Minnesota (2-4-1) when he came on in the 65th minute, scored when his shot was punched by goalkeeper Zac MacMath but deflected off Hansen into the net in the 78th. (apnews.com)
Goal1
- I mean the game was really good for us as a team and we worked so hard as a team and had a good result, and today was my turn to score a goal, but the important thing is that we went through as a team. (epluribusloonum.com)
Status1
- The result is a VCF file in which variants have been assigned a score and filter status. (broadinstitute.org)
File1
- The resulting file, consists of the {@link ClusteredCrosscheckMetric} class and contains the original crosscheck metric values, for groups that end-up in the same clusters (regardless of LOD score of each comparison). (broadinstitute.org)
Result1
- The result is a score called the VQSLOD that gets added to the INFO field of each variant. (broadinstitute.org)
Post1
- Hey guys, this is my first post and my very first question is why does my newly purchased Radeon 9700 PRO posted only 7185 3DMark Score when comparing to other Radeons Scored around 11000. (anandtech.com)
Card1
- No playing with the lod or overclocking the video card. (anandtech.com)
Chromosome11
- QTL analysis showed a peak logarithm of odds ratio score 5.78 on chromosome 19 (p = 0.002). (nih.gov)
- Two-point LOD scores for linkage between autosomal dominant congenital cataract locus and chromosome 12 markers. (molvis.org)
- Using the microsatellite DNA polymorphisms (STRPs) D14S53, D14S55, D14S48, and D14S45, we found significantly positive lod scores in 16 Portuguese kindreds, suggesting that the MJD locus is linked to chromosome 14q in this population. (nih.gov)
- Preliminary results revealed strong evidence of linkage to HPC on chromosome 15q was (LOD=4.9, 132cM) and 8q (LOD=3.1, 157cM). (nih.gov)
- Four patients from families with parental consanguinity were subjected to homozygosity mapping that identified a second IIH gene locus on chromosome 5q35 with a maximum logarithm of odds (LOD) score of 6.79. (uzh.ch)
- Results: All affected individuals shared a 20.4 Mb (3.25 cM) region of homozygosity located on chromosome 16q21-q23.1, defined by SNP markers rs149428 and rs9929635 (peak multipoint lod score of 4.86). (elsevier.com)
- Methods and Results - We obtained evidence for linkage of this potential QTL to the same locus (D6S311) on the baboon homologue of human chromosome 6 by using variance components and parametric linkage analysis methods (2-point lod scores 4.17 [genomic probability value 0.008] and 2.81 [genomic P=0.10], respectively). (uthscsa.edu)
- Multipoint linkage analysis showed a significant linkage of mild malaria to chromosome 6p21.3 (LOD score 3.73, P = 1.7 10 −5 ), a suggestive linkage of mild malaria to chromosome 19p13.12 (LOD score 2.50, P = 3.5 10 −4 ), and a suggestive linkage of asymptomatic parasitaemia to chromosomes 6p21.3 (LOD score 2.36, P = 4.9 10 −4 ) and 17p12 (LOD score 2.87, P = 1.4 10 −4 ). (biomedcentral.com)
- When taking into account 247 additional individuals, a significant linkage of asymptomatic parasitaemia to chromosome 17p12 (LOD score 3.6, P = 2 10 −5 ) was detected. (biomedcentral.com)
- The final region showing evidence for linkage, on chromosome 1q24-25 (near D1S218 [LOD score 1.50]), colocalizes with evidence for linkage to diabetes found in Utah, French, and Pima families and in the GK rat. (ox.ac.uk)
- A QTL (QKr1.2) for K+ content in the root was identified with the highest LOD score (7.8), on chromosome 1. (ijbiotech.com)
Multipoint lod score3
- A maximum multipoint lod score of 10.61 was found at marker D8S519. (bmj.com)
- Genetic linkage analysis in 12 families using markers from a deletion site demonstrated the presence of a high-penetrance locus in distal 19p with a multipoint lod score of 7.00 at marker D19S886 without evidence of genetic heterogeneity. (ox.ac.uk)
- The multipoint LOD score was 4.53 at microsatellite marker D21S1259, and fine mapping defined a -1.5 Mb critical region between microsatellite marker D21S1897 and the telomere of the long arm. (hud.ac.uk)
Chromosomes1
- The strongest evidence was seen on chromosomes 8p21-22 (near D8S258 [LOD score 2.55]) and 10q23.3 (near D10S1765 [LOD score 1.99]), both coinciding with regions identified in previous scans in European subjects. (ox.ac.uk)
Locus8
- A population was simulated with a six locus disease, with three contributing loci of high frequency but low impact (scenario F) and three contributing loci with high impact but low frequency (scenario R). LOD score as a function of the number of analysed sib pairs is shown, as calculated by the SIPPAIR program in 60 replicate studies, which were conducted in sib pairs randomly drawn from the population. (bmj.com)
- These terms describe the dosage scores of SNP markers, essentially the count of the number of "alternative" alleles present at a particular locus in an individual. (rstudio.com)
- Microsatellite markers spanning the CS/BZS locus (D10S219, D10S551, D10S579, and D10S541) were used to compute multipoint lod scores in eight informative families with JPS. (ox.ac.uk)
- All six demonstrated heterozygosity and negative LOD scores at the POMT1 locus. (elsevier.com)
- Linkage to the D 2 dopamine receptor locus was strongly excluded (lod = -4.02 at θ = 0.0). (elsevier.com)
- Two-locus linkage analysis, using a multiplicative risk model for the development of NMTC, achieved a maximum LOD of 3.92, with an LOD of 4.51 when assuming 70% of families were linked, indicating that the segregation in these families is consistent with an interaction model. (edu.au)
- Most of this evidence came from a large Tyrolean family that singularly achieved a two-locus LOD of 3.21. (edu.au)
- We mapped a BBS locus to a 10.1Mb region at 12q15-q21.2 in a large Omani BBS family (peak lod score 8.3 at θ=0.0 for marker D12S1722) that contained the recently described BBS10 locus. (elsevier.com)
Loci3
- Linkage analyses of 6 multiplex MSA families revealed several loci showing positive heterogeneity lod (HLOD) scores. (jnss.org)
- The heterogeneity LOD (HLOD) at the 6q, 2p and 14q loci in all families was 3.27, 1.66 and 1.24, respectively. (biomedcentral.com)
- Loci on 7p15.3 (LOD score 1.31) and 8q24.2 (LOD score 1.41) are novel. (ox.ac.uk)
Point lod scores2
- Lod score calculations confirmed linkage to this region with two point lod scores above 6. (bmj.com)
- Two-point lod scores were calculated, haplotypes were formed by inspection, and candidate genes were sequenced. (elsevier.com)
Negative LOD scores1
- A summary of some negative lod scores for exclusion of linkage with HLA is given in Table IV. (nih.gov)
Recombination fraction4
- A peak lod score of 4.52 at recombination fraction zero was obtained between the two C8 genes. (nih.gov)
- 1986) the maximum lod score is 7.53 at recombination fraction zero. (nih.gov)
- The compiled C8-PGM1 linkage data from this and the previous study gave a maximum lod score of 22.02 at recombination fraction 0.11 (0.07-0.16) with no sex difference. (nih.gov)
- Thus, the presence of families of mixed population ancestry impacts linkage analysis in terms of the LOD score and the estimate of the recombination fraction. (unthsc.edu)
Peak lod2
- In the present study we have evaluated CD44, a gene very close (0.5 cM) to the peak LOD score marker, as a candidate gene. (nih.gov)
- Multipoint linkage analysis of maximum recorded IOP produced a peak LOD score of 3.3 (P = 0.00015) near marker D10S537 on 10q22, whereas the maximum cup-to-disc ratio produced a peak LOD score of 2.3 (P = 0.00056) near markers D1S197 to D1S220 on 1p32. (uthscsa.edu)
Marker4
- The pairwise lod scores for linkage to marker D2S123 in these kindreds were 6.39 and 1.45 at zero recombination, and multipoint linkage with flanking markers resulted in lod scores of 6.47 and 6.01. (elsevier.com)
- 2 ] proposed to assign a weight to each affected sibling pair according to their SNP genotypes and then test whether these weights are correlated with the scoring function S pairs at a microsatellite marker [ 3 ]. (biomedcentral.com)
- Trmq1 (for T cell ratio modifier QTL 1) was detected in the telomeric end of c6 (peak marker D6Mit15 at 74 cM) and had a maximum LOD score of 4.6. (elsevier.com)
- After dense-map genotyping (mean marker spacing 4.4 cM), evidence for linkage to this region increased to a LOD score of 1.98. (ox.ac.uk)
Markers7
- Two out of five of the microsatellite markers showed a LOD score higher than 3. (biomedcentral.com)
- In the genome-wide scan, maximum lod scores of 2.67 and 2.77 for family 60004 and 2.02 and 2.04 for family 60006 were obtained for markers D22S539 and D22S315, respectively. (elsevier.com)
- However, this lod is not statistically significant, and its meaning is further mitigated by strongly negative lods in two nearby flanking markers. (elsevier.com)
- this amount buy 915363-56-3 implies that linkage analyses using allele frequencies within the Swedish control people gave LOD ratings >3 buy 915363-56-3 with four markers: and Of the, only provided LOD ratings >2 when allele frequencies within the pedigree had been utilized (fig. 3and desk 1). (cp-724714.com)
- We performed 37,000 simulations (370 markers simulated 100 situations each) and 296,000 LOD-score computations (each one of the simulated pedigrees was put through eight LOD-score computations, for all combos of allele frequencies and diagnostic groupings). (cp-724714.com)
- Desk 1 implies that nine markers contained in the genome check produced LOD ratings greater than the suggestive worth of 2.2: markers and Desk 1 also contains additional markers buy 915363-56-3 with LOD ratings >1.5, for comparisons with other research. (cp-724714.com)
- The outcomes supported just the positive linkage for Two-point LOD ratings for six extra markers located near are proven in amount 4. (cp-724714.com)
20222
- Apr 07, 2022 · LoD HotA Solo Push View all variants. (sv-alemannia-rommelsheim.de)
- Check out CAT 2022 slot 1 unofficial answer key to predict your CAT score. (careers360.com)
Luis amarilla2
- Robin lod, jacori hayes, luis amarilla and marlon harrison all scored roulette 777 online in the win. (luminiprogress.co.uk)
- Robin Lod and Luis Amarilla, two prolific attacking threats, were on the bench. (kslsports.com)
Suggestive3
- Linkage analyses of serum levels of apolipoprotein B dietary response, a correlated trait, also gave weak suggestive evidence of linkage to this chromosomal region (maximum 2-point lod score 1.91). (uthscsa.edu)
- One family contributed suggestive LOD scores (LOD 2.63 to 3.03, dominant model) at all these regions, without consistent evidence of a tumour suppressor gene. (biomedcentral.com)
- These simulations indicated that, for buy 915363-56-3 the pedigree versions and framework found in today's research, a LOD rating >2.2 is highly recommended seeing that suggestive whereas a LOD rating >3.7 is highly recommended as significant (fig. 2). (cp-724714.com)
Empirical3
- Permutations are ongoing to determine empirical p-values for these LOD scores. (nih.gov)
- For the significant linkage score, 1000 replicates were performed to calculate the empirical P-value.Results: The PSMD9 gene SNPs studied show linkage to hypercholesterolemia. (elsevier.com)
- To judge the importance of the full total outcomes, we performed an entire simulation from the genome scan, using all versions to compute empirical LOD ratings for the pedigree, beneath the assumption of no linkage. (cp-724714.com)
Genome1
- a LOD-score threshold was the common eight-model MLS worth that might be expected to take place, by possibility, once in 20 genome scans. (cp-724714.com)
Heterozygosity1
- However, heterozygosity for the H2 complex was suggestively associated (LOD score of 2.43) with increases in CD4 T cells among T cell precursors in the thymus. (elsevier.com)
Allele1
- The Ch- allele is in significant linkage disequilibrium with B12 and BW35 (formerly w5y2r28, Further data have added to the lod scores between PGM-3 and HLA, as indicated in Table III. (nih.gov)
Analyses1
- The measurements from replicate LC-MS analyses are depicted as the same symbol [3] The LOD was determined using a non-parametric method with eight LC-MS analyses without added analyte [4]. (darkkinome.org)
Equalizer1
- Lod scored the equalizer for United (4-5-3) wit. (taiwannews.com.tw)
20171
- I was feeling the pressure of not scoring with this jersey,' said Lazio striker Immobile whose last international goal was in a World Cup qualifier against Israel in September 2017. (deccanchronicle.com)
Gene3
- Using a newly identified short DNA repeat within the CD44 gene, we find a LOD score of 2.7, which confirms linkage within this genetic interval. (nih.gov)
- To potentially further optimize imputation performance of gene expression across global populations, we built transcriptome prediction models using both linear and non-linear machine learning (ML) algorithms and evaluated their performance in comparison to EN. (bvsalud.org)
- We report on a large kindred in which we were able to demonstrate very tight linkage between the disease and the type II collagen gene (COL2A1) (LOD score 3.91 at theta = 0). (shengsci.com)
Linkage group2
- CRIMAP analysis using a limits-of-detection (LOD) score of 5.0 placed ShIL1-21 in linkage group 14 of Shrimp Map whereas ShIL1-28 remained unlinked. (thefreedictionary.com)
- 1) (2) (3) BODME tr 8 N The assignment of GLO to this linkage group shel Ty a7 Combined lod scores for GLO-HLA are given in Table II. (nih.gov)
Family3
- Linkage analysis in the second family detected five regions with LOD scores approaching the highest values possible in the family. (nih.gov)
- Results and Conclusions: We observed that the LOD scores under both models of admixture were closest to the homogeneous family scores of the population having the highest mixing proportion. (unthsc.edu)
- Multiple homozygosity intervals were obtained for each family since no significant LOD scores were possible. (qscience.com)
Found4
- They found a significant peak single point logarithm of odds (LOD) score for Crohn's disease at D3S3591 and for IBD near D3S1304 (distal 3p) and D3S1283, providing. (the-scientist.com)
- LendingTree, the nation's leading online loan marketplace, today released itsreportthat found personal loans may increase credit scores of most borrowers. (thefreedictionary.com)
- The highest lod score was found at D11S29 (lod = 1.63 at θ = 0.1), which is in the general region of the reported translocation breakpoints. (elsevier.com)
- Once GW.net basically died, and RMN was born, LoD found new life as one of the first featured games on the site. (rpgmaker.net)
Quality score recalibration1
- This tool performs the first pass in a two-stage process called Variant Quality Score Recalibration (VQSR). (broadinstitute.org)
Parametric2
- Most transcriptome prediction models have been trained in European populations using methods that make parametric linear assumptions like the elastic net (EN). (bvsalud.org)
- Multipoint logarithm of odds (LOD) scores were calculated using parametric and nonparametric methods. (biomedcentral.com)
Robin8
- SAINT PAUL, Minn. (AP) - Robin Lod scored in the 87th minute to help Minnesota United earn a 1-1 draw with the LA Galaxy on Wednesday. (taiwannews.com.tw)
- Robin Lod has been Minnesota's main man so far this season, scoring six times in 12 MLS appearances. (me.uk)
- Emanuel Reyoso has scored nine, Luis Amirilla has scored eight and Robin Lod has scored six goals this season. (wsn.com)
- Amarilla's attempt was blocked by Vega, but Robin Lod scored on the follow-up to make it 4-1. (centerlinesoccer.com)
- Robin Lod scored a late goal and Minnesota United beat Seattle 1-0 to end the Sounders' MLS-record 13-game unbeaten streak to open a season. (krod.com)
- Robin Lod is a Finnish professional football player who plays as an attacking midfielder for an MLS team, Minnesota United, and the Finland national team. (playerswiki.com)
- However seven minutes later Italy were ahead again, with another penalty taken by Jorginho, after being fouled by Robin Lod. (deccanchronicle.com)
- Well, look, Robin [Lod] [being injured] it was like two days ago so it's one of those things where it's sprung on us, unfortunately, and I think guys have to step up. (epluribusloonum.com)
Calculations1
- For OP Score's beta test, based on the characteristics of each match your results may be somewhat inaccurate We will keep trying to improve the indicators and calculations used in OP Score so we can create the most objective rating possible. (op.gg)
Major League1
- After featuring in 23 of their games with four goals scored, Lod started to play for Major League Soccer competitor, Minnesota United. (playerswiki.com)
Galaxy2
- Score LA Galaxy Game Today. (soccergames-today.com)
- View Score LA Galaxy Today. (soccergames-today.com)
Disease1
- Design and Methods: Through simulation, we investigated the effect of admixture of two populations on the LOD score under various conditions, using prostate cancer as our underlying disease model. (unthsc.edu)
Significant1
- Although the highest OSA LOD score with a ΔLOD (p=0.02) was 2.876 on 15q26.2-q26.3 in a subset of 40 families ascending by age at onset, no other ΔLOD scores were significant after permutation testing. (nih.gov)
Hunou1
- Outside of Klinsmann's performance MNUFC also struggled scoring, something they and Adrien Hunou have had issues with this season. (epluribusloonum.com)
Reflects2
- 3. Instrument Limit of Detection Modeling - Limit of Detection (LOD) reflects an (medical diagnostic) instrument's level of sensitivity. (r-project.org)
- The thickness of each line reflects a confidence score, with thicker lines higher in confidence. (darkkinome.org)
Evidence1
- Results: The 10 families provided evidence for linkage at both TCO and NMTC, with LOD scores of 1.56 and 2.85, respectively. (edu.au)
20191
- Active since 2019, he has made 9 goals scored in 35 appearances. (playerswiki.com)
20161
- Brooklyn rapper Desiigner scored a surprise No. 1 hit in 2016 with "Panda. (apple.com)
Data1
- Recently, with the initiative of « Linked Open Data cloud (LOD) », the number of sources of structured data made available on the Web has lead to an explosive growth of the global data space with billions of assertions (61 billions in January 2014). (lri.fr)
Families1
- Introduction: Families of admixed ancestry are routinely excluded from traditional (Log of the Odds [LOD] score) linkage analysis or are analyzed as being derived from a homogeneous population using the proband's ethnicity. (unthsc.edu)
Analysis2
- Edwards' programs, ZLODS and OBM, were used for joint analysis of the lod scores. (gla.ac.uk)
- Features for linkage analysis include singlepoint LOD scores, power analysis, and multipoint analysis (the latter through a wrapper to the 'MERLIN' software). (microsoft.com)