Diagnostic procedures involving immunoglobulin reactions.
Pathological processes of the LIVER.
A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.
The transference of a part of or an entire liver from one human or animal to another.
Tumors or cancer of the LIVER.
Serologic tests for syphilis.
Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
Serologic tests based on inactivation of complement by the antigen-antibody complex (stage 1). Binding of free complement can be visualized by addition of a second antigen-antibody system such as red cells and appropriate red cell antibody (hemolysin) requiring complement for its completion (stage 2). Failure of the red cells to lyse indicates that a specific antigen-antibody reaction has taken place in stage 1. If red cells lyse, free complement is present indicating no antigen-antibody reaction occurred in stage 1.
Tests that are dependent on the clumping of cells, microorganisms, or particles when mixed with specific antiserum. (From Stedman, 26th ed)
Closed vesicles of fragmented endoplasmic reticulum created when liver cells or tissue are disrupted by homogenization. They may be smooth or rough.
An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.
A disease of cattle caused by bacteria of the genus BRUCELLA leading to abortion in late pregnancy. BRUCELLA ABORTUS is the primary infective agent.
Repair or renewal of hepatic tissue.
Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.
Immunoglobulins produced in a response to BACTERIAL ANTIGENS.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
A contagious venereal disease caused by the spirochete TREPONEMA PALLIDUM.
Sensitive tests to measure certain antigens, antibodies, or viruses, using their ability to agglutinate certain erythrocytes. (From Stedman, 26th ed)
Infection caused by bacteria of the genus BRUCELLA mainly involving the MONONUCLEAR PHAGOCYTE SYSTEM. This condition is characterized by fever, weakness, malaise, and weight loss.
Precipitin tests which occur over a narrow range of antigen-antibody ratio, due chiefly to peculiarities of the antibody (precipitin). (From Stedman, 26th ed)
Blood tests that are used to evaluate how well a patient's liver is working and also to help diagnose liver conditions.
Mitochondria in hepatocytes. As in all mitochondria, there are an outer membrane and an inner membrane, together creating two separate mitochondrial compartments: the internal matrix space and a much narrower intermembrane space. In the liver mitochondrion, an estimated 67% of the total mitochondrial proteins is located in the matrix. (From Alberts et al., Molecular Biology of the Cell, 2d ed, p343-4)
A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, and chemicals from the environment.
A bright bluish pink compound that has been used as a dye, biological stain, and diagnostic aid.
A genus of gram-negative, aerobic bacteria that causes BRUCELLOSIS. Its cells are nonmotile coccobacilli and are animal parasites and pathogens. The bacterium is transmissible to humans through contact with infected dairy products or tissue.
A class of immunoglobulin bearing mu chains (IMMUNOGLOBULIN MU-CHAINS). IgM can fix COMPLEMENT. The name comes from its high molecular weight and originally being called a macroglobulin.
Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.
The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.
Positive test results in subjects who do not possess the attribute for which the test is conducted. The labeling of healthy persons as diseased when screening in the detection of disease. (Last, A Dictionary of Epidemiology, 2d ed)
Extracts of liver tissue containing uncharacterized specific factors with specific activities; a soluble thermostable fraction of mammalian liver is used in the treatment of pernicious anemia.
The circulation of BLOOD through the LIVER.
Experimentally induced tumors of the LIVER.
Substances elaborated by bacteria that have antigenic activity.
Syphilis acquired in utero and manifested by any of several characteristic tooth (Hutchinson's teeth) or bone malformations and by active mucocutaneous syphilis at birth or shortly thereafter. Ocular and neurologic changes may also occur.
Technique involving the diffusion of antigen or antibody through a semisolid medium, usually agar or agarose gel, with the result being a precipitin reaction.
Studies determining the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies. For drugs and devices, CLINICAL TRIALS AS TOPIC; DRUG EVALUATION; and DRUG EVALUATION, PRECLINICAL are available.
Infections with bacteria of the genus TREPONEMA.
A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
Immunoglobulins produced in a response to PROTOZOAN ANTIGENS.
Syphilis serodiagnosis employing as the antigen Treponema pallidum obtained from rabbit syphilis orchitis. Treponemes are kept alive for a few hours in a special medium. When syphilitic serum and complement are added and incubated, the treponemes are immobilized, i.e., stop moving.
Commercially prepared reagent sets, with accessory devices, containing all of the major components and literature necessary to perform one or more designated diagnostic tests or procedures. They may be for laboratory or personal use.
Immunoelectrophoresis in which immunoprecipitation occurs when antigen at the cathode is caused to migrate in an electric field through a suitable medium of diffusion against a stream of antibody migrating from the anode as a result of endosmotic flow.
Solitary or multiple collections of PUS within the liver as a result of infection by bacteria, protozoa, or other agents.
Liver diseases associated with ALCOHOLISM. It usually refers to the coexistence of two or more subentities, i.e., ALCOHOLIC FATTY LIVER; ALCOHOLIC HEPATITIS; and ALCOHOLIC CIRRHOSIS.
The agent of South American trypanosomiasis or CHAGAS DISEASE. Its vertebrate hosts are man and various domestic and wild animals. Insects of several species are vectors.
Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
Immunoglobulins produced in response to VIRAL ANTIGENS.
Serological reactions in which an antiserum against one antigen reacts with a non-identical but closely related antigen.
A species of the genus BRUCELLA whose natural hosts are cattle and other bovidae. Abortion and placentitis are frequently produced in the pregnant animal. Other mammals, including humans, may be infected.
EPIDEMIOLOGIC STUDIES based on the detection through serological testing of characteristic change in the serum level of specific ANTIBODIES. Latent subclinical infections and carrier states can thus be detected in addition to clinically overt cases.
Passive agglutination tests in which antigen is adsorbed onto latex particles which then clump in the presence of antibody specific for the adsorbed antigen. (From Stedman, 26th ed)
An infectious disease caused by a spirochete, BORRELIA BURGDORFERI, which is transmitted chiefly by Ixodes dammini (see IXODES) and pacificus ticks in the United States and Ixodes ricinis (see IXODES) in Europe. It is a disease with early and late cutaneous manifestations plus involvement of the nervous system, heart, eye, and joints in variable combinations. The disease was formerly known as Lyme arthritis and first discovered at Old Lyme, Connecticut.
The causative agent of venereal and non-venereal syphilis as well as yaws.
Excision of all or part of the liver. (Dorland, 28th ed)
The main structural component of the LIVER. They are specialized EPITHELIAL CELLS that are organized into interconnected plates called lobules.
Immunoglobulins produced in a response to HELMINTH ANTIGENS.
Represents 15-20% of the human serum immunoglobulins, mostly as the 4-chain polymer in humans or dimer in other mammals. Secretory IgA (IMMUNOGLOBULIN A, SECRETORY) is the main immunoglobulin in secretions.
Infection with a fungus of the genus COCCIDIOIDES, endemic to the SOUTHWESTERN UNITED STATES. It is sometimes called valley fever but should not be confused with RIFT VALLEY FEVER. Infection is caused by inhalation of airborne, fungal particles known as arthroconidia, a form of FUNGAL SPORES. A primary form is an acute, benign, self-limited respiratory infection. A secondary form is a virulent, severe, chronic, progressive granulomatous disease with systemic involvement. It can be detected by use of COCCIDIOIDIN.
Antibodies, especially IGE, that bind to tissue of the same species so that ANTIGENS induce release of HISTAMINE and other vasoactive agents. HYPERSENSITIVITY is the clinical manifestation.
Immunologic techniques involved in diagnosis.
A chronic disease caused by LEISHMANIA DONOVANI and transmitted by the bite of several sandflies of the genera Phlebotomus and Lutzomyia. It is commonly characterized by fever, chills, vomiting, anemia, hepatosplenomegaly, leukopenia, hypergammaglobulinemia, emaciation, and an earth-gray color of the skin. The disease is classified into three main types according to geographic distribution: Indian, Mediterranean (or infantile), and African.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Experimentally induced chronic injuries to the parenchymal cells in the liver to achieve a model for LIVER CIRRHOSIS.
Elements of limited time intervals, contributing to particular results or situations.
A species of the genus BRUCELLA whose natural hosts are sheep and goats. Other mammals, including humans, may be infected. In general, these organisms tend to be more virulent for laboratory animals than BRUCELLA ABORTUS and may cause fatal infections.
A family of terrestrial carnivores with long, slender bodies, long tails, and anal scent glands. They include badgers, weasels, martens, FERRETS; MINKS; wolverines, polecats, and OTTERS.
A severe form of LEPTOSPIROSIS, usually caused by LEPTOSPIRA INTERROGANS SEROVAR ICTEROHAEMORRHAGIAE and occasionally other serovars. It is transmitted to humans by the rat and is characterized by hemorrhagic and renal symptoms with accompanying JAUNDICE.
FIBROSIS of the hepatic parenchyma due to chronic excess ALCOHOL DRINKING.
Immunoglobulins produced in a response to FUNGAL ANTIGENS.
Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.
INFLAMMATION of the LIVER.
Infections of the central nervous system caused by TREPONEMA PALLIDUM which present with a variety of clinical syndromes. The initial phase of infection usually causes a mild or asymptomatic meningeal reaction. The meningovascular form may present acutely as BRAIN INFARCTION. The infection may also remain subclinical for several years. Late syndromes include general paresis; TABES DORSALIS; meningeal syphilis; syphilitic OPTIC ATROPHY; and spinal syphilis. General paresis is characterized by progressive DEMENTIA; DYSARTHRIA; TREMOR; MYOCLONUS; SEIZURES; and Argyll-Robertson pupils. (Adams et al., Principles of Neurology, 6th ed, pp722-8)
Immunologic techniques based on the use of: (1) enzyme-antibody conjugates; (2) enzyme-antigen conjugates; (3) antienzyme antibody followed by its homologous enzyme; or (4) enzyme-antienzyme complexes. These are used histologically for visualizing or labeling tissue specimens.
Devices for simulating the activities of the liver. They often consist of a hybrid between both biological and artificial materials.
Glycogen stored in the liver. (Dorland, 28th ed)
Diseases of domestic cattle of the genus Bos. It includes diseases of cows, yaks, and zebus.
A form of fluorescent antibody technique commonly used to detect serum antibodies and immune complexes in tissues and microorganisms in specimens from patients with infectious diseases. The technique involves formation of an antigen-antibody complex which is labeled with fluorescein-conjugated anti-immunoglobulin antibody. (From Bennington, Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)
A self-limiting bacterial infection of the regional lymph nodes caused by AFIPIA felis, a gram-negative bacterium recently identified by the Centers for Disease Control and Prevention and by BARTONELLA HENSELAE. It usually arises one or more weeks following a feline scratch, with raised inflammatory nodules at the site of the scratch being the primary symptom.
The acquired form of infection by Toxoplasma gondii in animals and man.
Infections with bacteria of the genus LEPTOSPIRA.
Diseases of the domestic dog (Canis familiaris). This term does not include diseases of wild dogs, WOLVES; FOXES; and other Canidae for which the heading CARNIVORA is used.
An enzyme that catalyzes the conversion of L-alanine and 2-oxoglutarate to pyruvate and L-glutamate. (From Enzyme Nomenclature, 1992) EC 2.6.1.2.
An infection caused by the infestation of the larval form of tapeworms of the genus Echinococcus. The liver, lungs, and kidney are the most common areas of infestation.
A systemic non-venereal infection of the tropics caused by TREPONEMA PALLIDUM subspecies pertenue.
Final stage of a liver disease when the liver failure is irreversible and LIVER TRANSPLANTATION is needed.
A species of gram-negative bacteria that is the etiologic agent of bacillary angiomatosis (ANGIOMATOSIS, BACILLARY). This organism can also be a cause of CAT-SCRATCH DISEASE in immunocompetent patients.
The study of parasites and PARASITIC DISEASES.
Anogenital ulcers caused by Calymmatobacterium granulomatis as distinguished from lymphogranuloma inguinale (see LYMPHOGRANULOMA VENEREUM) caused by CHLAMYDIA TRACHOMATIS. Diagnosis is made by demonstration of typical intracellular Donovan bodies in crushed-tissue smears.
A bacterial vaccine for the prevention of brucellosis in man and animal. Brucella abortus vaccine is used for the immunization of cattle, sheep, and goats.
A spiral bacterium active as a human gastric pathogen. It is a gram-negative, urease-positive, curved or slightly spiral organism initially isolated in 1982 from patients with lesions of gastritis or peptic ulcers in Western Australia. Helicobacter pylori was originally classified in the genus CAMPYLOBACTER, but RNA sequencing, cellular fatty acid profiles, growth patterns, and other taxonomic characteristics indicate that the micro-organism should be included in the genus HELICOBACTER. It has been officially transferred to Helicobacter gen. nov. (see Int J Syst Bacteriol 1989 Oct;39(4):297-405).
A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
Any part or derivative of any protozoan that elicits immunity; malaria (Plasmodium) and trypanosome antigens are presently the most frequently encountered.
The study of serum, especially of antigen-antibody reactions in vitro.
A malabsorption syndrome that is precipitated by the ingestion of foods containing GLUTEN, such as wheat, rye, and barley. It is characterized by INFLAMMATION of the SMALL INTESTINE, loss of MICROVILLI structure, failed INTESTINAL ABSORPTION, and MALNUTRITION.
A method for diagnosing a disease in one organism by inoculating the putative causative organism in a second animal of a different species. It has been used for the detection of parasites (Trypanosoma cruzi and Trichinella spiralis) when peripheral blood smears are negative. (Segen, Current Med Talk, 1995)
Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease.
Interstitial pneumonia caused by extensive infection of the lungs (LUNG) and BRONCHI, particularly the lower lobes of the lungs, by MYCOPLASMA PNEUMONIAE in humans. In SHEEP, it is caused by MYCOPLASMA OVIPNEUMONIAE. In CATTLE, it may be caused by MYCOPLASMA DISPAR.
Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.
Diseases of domestic and mountain sheep of the genus Ovis.
Short filamentous organism of the genus Mycoplasma, which binds firmly to the cells of the respiratory epithelium. It is one of the etiologic agents of non-viral primary atypical pneumonia in man.
Premature expulsion of the FETUS in animals.
Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).
A genus of protozoa parasitic to birds and mammals. T. gondii is one of the most common infectious pathogenic animal parasites of man.
Techniques used to carry out clinical investigative procedures in the diagnosis and therapy of disease.
Gram-negative helical bacteria, in the genus BORRELIA, that are the etiologic agents of LYME DISEASE. The group comprises many specific species including Borrelia afzelii, Borellia garinii, and BORRELIA BURGDORFERI proper. These spirochetes are generally transmitted by several species of ixodid ticks.
Serologic tests in which a known quantity of antigen is added to the serum prior to the addition of a red cell suspension. Reaction result is expressed as the smallest amount of antigen which causes complete inhibition of hemagglutination.
A test to detect non-agglutinating ANTIBODIES against ERYTHROCYTES by use of anti-antibodies (the Coombs' reagent.) The direct test is applied to freshly drawn blood to detect antibody bound to circulating red cells. The indirect test is applied to serum to detect the presence of antibodies that can bind to red blood cells.
A genus of gram-negative, mostly facultatively anaerobic bacteria in the family MYCOPLASMATACEAE. The cells are bounded by a PLASMA MEMBRANE and lack a true CELL WALL. Its organisms are pathogens found on the MUCOUS MEMBRANES of humans, ANIMALS, and BIRDS.
A technique using antibodies for identifying or quantifying a substance. Usually the substance being studied serves as antigen both in antibody production and in measurement of antibody by the test substance.
A mitosporic fungal genus which causes COCCIDIOIDOMYCOSIS.
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Helminth infection of the lung caused by Echinococcus granulosus or Echinococcus multilocularis.
A genus of very small TAPEWORMS, in the family Taeniidae. The adult form is found in various CARNIVORA but not humans. The larval form is seen in humans under certain epidemiologic circumstances.
Infections of the BRAIN; SPINAL CORD; or MENINGES caused by HELMINTHS (parasitic worms).
A genus of bacteria causing GRANULOMA INGUINALE and other granulomatous lesions.
Serum that contains antibodies. It is obtained from an animal that has been immunized either by ANTIGEN injection or infection with microorganisms containing the antigen.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
An acute infectious disease caused by COXIELLA BURNETII. It is characterized by a sudden onset of FEVER; HEADACHE; malaise; and weakness. In humans, it is commonly contracted by inhalation of infected dusts derived from infected domestic animals (ANIMALS, DOMESTIC).
Skin tests in which the sensitizer is injected.
The region of the thorax that includes the PLEURAL CAVITY and MEDIASTINUM.
A genus of aerobic, helical spirochetes, some species of which are pathogenic, others free-living or saprophytic.
Infection of the genitals (GENITALIA) with HERPES SIMPLEX VIRUS in either the males or the females.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.
The constant presence of diseases or infectious agents within a given geographic area or population group. It may also refer to the usual prevalence of a given disease with such area or group. It includes holoendemic and hyperendemic diseases. A holoendemic disease is one for which a high prevalent level of infection begins early in life and affects most of the child population, leading to a state of equilibrium such that the adult population shows evidence of the disease much less commonly than do children (malaria in many communities is a holoendemic disease). A hyperendemic disease is one that is constantly present at a high incidence and/or prevalence rate and affects all groups equally. (Last, A Dictionary of Epidemiology, 3d ed, p53, 78, 80)
A species of SIMPLEXVIRUS associated with genital infections (HERPES GENITALIS). It is transmitted by sexual intercourse and close personal contact.
Semisynthetic antibiotic prepared by combining the sodium salt of penicillin G with N,N'-dibenzylethylenediamine.
A parasitic hemoflagellate of the subgenus Leishmania leishmania that infects man and animals and causes visceral leishmaniasis (LEISHMANIASIS, VISCERAL). Human infections are confined almost entirely to children. This parasite is commonly seen in dogs, other Canidae, and porcupines with humans considered only an accidental host. Transmission is by Phlebotomus sandflies.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
Substances elaborated by viruses that have antigenic activity.
Diseases of domestic swine and of the wild boar of the genus Sus.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Techniques used to demonstrate or measure an immune response, and to identify or measure antigens using antibodies.
Immunologic method used for detecting or quantifying immunoreactive substances. The substance is identified by first immobilizing it by blotting onto a membrane and then tagging it with labeled antibodies.
A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)
Substances of fungal origin that have antigenic activity.
Transglutaminases catalyze cross-linking of proteins at a GLUTAMINE in one chain with LYSINE in another chain. They include keratinocyte transglutaminase (TGM1 or TGK), tissue transglutaminase (TGM2 or TGC), plasma transglutaminase involved with coagulation (FACTOR XIII and FACTOR XIIIa), hair follicle transglutaminase, and prostate transglutaminase. Although structures differ, they share an active site (YGQCW) and strict CALCIUM dependence.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Antibodies which elicit IMMUNOPRECIPITATION when combined with antigen.
Inflammation of the lymph nodes.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Any of numerous agile, hollow-horned RUMINANTS of the genus Capra, in the family Bovidae, closely related to the SHEEP.
INFLAMMATION of the LIVER in humans caused by a member of the ORTHOHEPADNAVIRUS genus, HEPATITIS B VIRUS. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact.
Disease having a short and relatively severe course.
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Proteins prepared by recombinant DNA technology.
Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.
Species of tapeworm in the genus TAENIA, that infects swine. It is acquired by humans through the ingestion of cured or undercooked pork.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
Specialized phagocytic cells of the MONONUCLEAR PHAGOCYTE SYSTEM found on the luminal surface of the hepatic sinusoids. They filter bacteria and small foreign proteins out of the blood, and dispose of worn out red blood cells.
The rate dynamics in chemical or physical systems.
The property of antibodies which enables them to react with some ANTIGENIC DETERMINANTS and not with others. Specificity is dependent on chemical composition, physical forces, and molecular structure at the binding site.
Agents destructive to the protozoal organisms belonging to the suborder TRYPANOSOMATINA.
A genus of microorganisms of the order SPIROCHAETALES, many of which are pathogenic and parasitic for man and animals.
Single or multiple areas of PUS due to infection by any ameboid protozoa (AMEBIASIS). A common form is caused by the ingestion of ENTAMOEBA HISTOLYTICA.
A chronic GASTROENTERITIS in RUMINANTS caused by MYCOBACTERIUM AVIUM SUBSPECIES PARATUBERCULOSIS.
A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They include numerous complex monooxygenases (MIXED FUNCTION OXYGENASES). In animals, these P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs (BIOTRANSFORMATION). They are classified, according to their sequence similarities rather than functions, into CYP gene families (>40% homology) and subfamilies (>59% homology). For example, enzymes from the CYP1, CYP2, and CYP3 gene families are responsible for most drug metabolism.
A deep type of gyrate erythema that follows a bite by an ixodid tick; it is a stage-1 manifestation of LYME DISEASE. The site of the bite is characterized by a red papule that expands peripherally as a nonscaling, palpable band that clears centrally. This condition is often associated with systemic symptoms such as chills, fever, headache, malaise, nausea, vomiting, fatigue, backache, and stiff neck.
The processes triggered by interactions of ANTIBODIES with their ANTIGENS.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
The co-occurrence of pregnancy and an INFECTION. The infection may precede or follow FERTILIZATION.
A subspecies of gram-positive, aerobic bacteria. It is the etiologic agent of Johne's disease (PARATUBERCULOSIS), a chronic GASTROENTERITIS in RUMINANTS.
A mycosis affecting the skin, mucous membranes, lymph nodes, and internal organs. It is caused by Paracoccidioides brasiliensis. It is also called paracoccidioidal granuloma. Superficial resemblance of P. brasiliensis to Blastomyces brasiliensis (BLASTOMYCES) may cause misdiagnosis.
Epicutaneous or intradermal application of a sensitizer for demonstration of either delayed or immediate hypersensitivity. Used in diagnosis of hypersensitivity or as a test for cellular immunity.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
A short thick vein formed by union of the superior mesenteric vein and the splenic vein.
Prenatal protozoal infection with TOXOPLASMA gondii which is associated with injury to the developing fetal nervous system. The severity of this condition is related to the stage of pregnancy during which the infection occurs; first trimester infections are associated with a greater degree of neurologic dysfunction. Clinical features include HYDROCEPHALUS; MICROCEPHALY; deafness; cerebral calcifications; SEIZURES; and psychomotor retardation. Signs of a systemic infection may also be present at birth, including fever, rash, and hepatosplenomegaly. (From Adams et al., Principles of Neurology, 6th ed, p735)
A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction.
A mitosporic fungal genus. P. brasiliensis (previously Blastomyces brasiliensis) is the etiologic agent of PARACOCCIDIOIDOMYCOSIS.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
The period of recovery following an illness.
An acute systemic febrile infection caused by SALMONELLA TYPHI, a serotype of SALMONELLA ENTERICA.
A genus of protozoan parasites of the subclass COCCIDIA. Its species are parasitic in dogs, cattle, goats, and sheep, among others. N. caninum, a species that mainly infects dogs, is intracellular in neural and other cells of the body, multiplies by endodyogeny, has no parasitophorous vacuole, and has numerous rhoptries. It is known to cause lesions in many tissues, especially the brain and spinal cord as well as abortion in the expectant mother.
The medical science concerned with the prevention, diagnosis, and treatment of diseases in animals.
Techniques used in studying bacteria.
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.
MYCOBACTERIUM infections of the lung.
The clumping together of suspended material resulting from the action of AGGLUTININS.
A graphic means for assessing the ability of a screening test to discriminate between healthy and diseased persons; may also be used in other studies, e.g., distinguishing stimuli responses as to a faint stimuli or nonstimuli.
Infection resulting from inhalation or ingestion of spores of the fungus of the genus HISTOPLASMA, species H. capsulatum. It is worldwide in distribution and particularly common in the midwestern United States. (From Dorland, 27th ed)
A disease of humans and animals that resembles GLANDERS. It is caused by BURKHOLDERIA PSEUDOMALLEI and may range from a dormant infection to a condition that causes multiple abscesses, pneumonia, and bacteremia.
Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Process of determining and distinguishing species of bacteria or viruses based on antigens they share.
Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.
Simple protein, one of the prolamines, derived from the gluten of wheat, rye, etc. May be separated into 4 discrete electrophoretic fractions. It is the toxic factor associated with CELIAC DISEASE.
A branch of the celiac artery that distributes to the stomach, pancreas, duodenum, liver, gallbladder, and greater omentum.
A species of parasitic protozoa causing ENTAMOEBIASIS and amebic dysentery (DYSENTERY, AMEBIC). Characteristics include a single nucleus containing a small central karyosome and peripheral chromatin that is finely and regularly beaded.
The channels that collect and transport the bile secretion from the BILE CANALICULI, the smallest branch of the BILIARY TRACT in the LIVER, through the bile ductules, the bile ducts out the liver, and to the GALLBLADDER for storage.
A specific species of bacteria, part of the BORRELIA BURGDORFERI GROUP, whose common name is Lyme disease spirochete.
A hemoflagellate subspecies of parasitic protozoa that causes Gambian or West African sleeping sickness in humans. The vector host is usually the tsetse fly (Glossina).
Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS.
Diseases of the domestic or wild goat of the genus Capra.
A genus of flagellate protozoa comprising several species that are pathogenic for humans. Organisms of this genus have an amastigote and a promastigote stage in their life cycles. As a result of enzymatic studies this single genus has been divided into two subgenera: Leishmania leishmania and Leishmania viannia. Species within the Leishmania leishmania subgenus include: L. aethiopica, L. arabica, L. donovani, L. enrietti, L. gerbilli, L. hertigi, L. infantum, L. major, L. mexicana, and L. tropica. The following species are those that compose the Leishmania viannia subgenus: L. braziliensis, L. guyanensis, L. lainsoni, L. naiffi, and L. shawi.
The measurement of an organ in volume, mass, or heaviness.
Serologic testing, radiological imaging and histological analysis can help diagnose SSC. First lines of treatment can include ... If these fail a liver transplant may be necessary. Abdalian R, Heathcote EJ (November 2006). "Sclerosing cholangitis: a focus ... Secondary sclerosing cholangitis (SSC) is a chronic cholestatic liver disease. SSC is a sclerosing cholangitis with a known ... and possibly a liver transplant. SSC is thought to develop as a consequence of known injuries or pathological processes of the ...
Serologic analysis can be also used - ELISA test for IgG antibodies against antigens of M. conjunctus. Drugs used to treat ... It lives in the bile duct and in the gallbladder. M. conjunctus causes a disease called metorchiasis. It has been known to ... Also, higher concentrations of liver enzymes are seen. When untreated, symptoms may last from 3 days to 4 weeks. Symptoms of ... Watson T. G & Croll N. A. (1981). "Clinical changes caused by the liver fluke Metorchis conjunctus in cats". Veterinary ...
If serologic tests detect a positive or high titer of IgG, this result should not automatically be interpreted to mean that ... Up to 5 of every 1,000 live births are infected. Five percent develop multiple handicaps, and develop cytomegalic inclusion ... The enzyme-linked immunosorbent assay (or ELISA) is the most commonly available serologic test for measuring antibody to CMV. ... However, routine testing of all pregnant women is costly and the need for testing should therefore be evaluated on a case-by- ...
... serologic tests, urinalysis, drug screening, imaging, and physical exams. For patients who are interested in liver ... Hospice patients are also able to live at peace away from a hospital setting; they may live at home with a hospice provider or ... However, patients in hospice care often live the same length of time as patients in the hospital. A study of 3850 liver cancer ... Initial screening measures include: blood tests, pregnancy tests, ...
... liver and kidney function tests, and serologic tests for parasitic and connective tissue diseases. The stool is often examined ... Specific test for causative conditions are performed, often including chest x-ray, urinalysis, ... Other examples of organ-restricted hepereosinophilia include those involving the heart, kidney, liver, colon, pulmonary pleurae ... and tests for serum LDH and other tumor markers. Based on their causes, hypereosinophilias can be sorted into subtypes. However ...
Infection can be confirmed through serologic IgM testing. The virus is found in the Mediterranean, Middle East, and parts of ... One study has suggested that living near wastewater treatment facilities and the presence of livestock inside the home are risk ... There is little or no serologic cross-reactivity between sandfly fever viruses. ...
Serologic tests may show a rising antibody titer during primary infection but are of no diagnostic assistance during recurrent ... Treatment of herpes of the eye is different based on its presentation: epithelial keratitis is caused by live virus while ... the test is low in sensitivity and specificity. DNA testing is rapid, sensitive and specific. However, its high cost limits its ... Diagnostic testing is seldom needed because of its classic clinical features and is not useful in stromal keratitis as there is ...
Serologic testing has also been used to diagnose the presence of botfly larvae in human ophthalmomyiasis. Play media Ultrasound ... Myiasis is the parasitic infestation of the body of a live animal by fly larvae (maggots) which grow inside the host while ... This is an important distinction, as most other major varieties of myiasitic fly larvae attack both live and dead wound tissue ... Larvae may infect dead, necrotic (prematurely dying) or living tissue in various sites: the skin, eyes, ears, stomach and ...
Some variant alleles cause a weak positive phenotype, which may be mistaken for a Lan-negative phenotype in serologic testing. ... fetal liver, mitochondrial membrane, and Golgi bodies.:220 The Lan antigen is more strongly expressed on cord blood cells than ... Serologic reagents and molecular assays for Lan antigen typing were not commercially available as of 2013. Anti-Lan antibodies ... As an IgG antibody, anti-Lan can be detected using the indirect antiglobulin test. The antibody is resistant to treatment with ...
A Sabin-Feldman dye test is a serologic test to diagnose for toxoplasmosis. The test is based on the presence of certain ... Drawbacks of this test: 1. Difficulty in maintaining the live tachyzoites. 2. It detects immunoglobulin G(IgG) antibodies, ... distorted and colorless is reported as antibody titer of the test serum. The test is highly sensitive and specific with no ... The dilution of the test serum at which 50% of the tachyzoites are thin, ...
Serologic testing is another diagnosis method that detects the virus within the birds through antibody tests and overseeing the ... However, these antibody tests are not as helpful in diagnosing birds that are already sick or those birds that do not live long ... Laboratory tests can also display the abnormalities of tissues, such as a liver with pale yellow to brown patches in necrotic ... By applying this test on post-mortem tissues, dark dispersed spotting on the liver and small intestines in necrotic areas ...
2007). "Accuracy of serologic tests and HLA-DQ typing for diagnosing celiac disease". Annals of Internal Medicine. 147 (5): 294 ... Bannai M, Tokunaga K, Imanishi T, Harihara S, Fujisawa K, Juji T, Omoto K (1996). "HLA class II alleles in Ainu living in ... Note some population test DR3 or DQA1:DQB1, the DR3-DQ2 serotype is generally synonymous in frequency with DQ2.5] DR3-DQ2 ... "HLA profile of three ethnic groups living in the North-Western region of Russia". Tissue Antigens. 59 (1): 38-43. doi:10.1034/j ...
This test, the microagglutination test (MAT), is a serologic test that tests the level of antibodies created by the immune ... Additionally, individuals living in a leptospira endemic region may have relatively high initial MAT test that only indicate ... "Leptospira Microagglutination Testing". Animal Health Diagnostic Testing. Cornell University. 26 February 2019. Hall C, ... Although this test has high specificity, it has low sensitivity, again indicating that it can miss many truly infected ...
An exception is in people who are immunocompromised in who serologic tests with viral identification can be used to confirm the ... Liver dysfunction can occur in rare cases.[citation needed] In rare cases, HHV-6 can become active in an adult previously ... Those who have been exposed or infected have been shown to shed the virus for the rest of their lives. Because of this, there ... Diagnosis is typically based on symptoms but can be confirmed with blood tests. Low numbers of white blood cells may also be ...
Culture or PCR are the current means for detecting the presence of the organism, as serologic studies only test for antibodies ... However, according to the CDC, live spirochetes have not been found in breast milk, urine, or semen and thus is not sexually ... Blood tests are often negative in the early stages of the disease. Testing of individual ticks is not typically useful. ... As all people with later-stage infection will have a positive antibody test, simple blood tests can exclude Lyme disease as a ...
In addition, serologic tests including antibodies to a host of viruses have consistently proven noncontributory and no viral ... Recurrence rate is about 3%. Death from Kikuchi disease is extremely rare and usually occurs due to liver, respiratory, or ... Rarely, enlargement of the liver and spleen and nervous system involvement resembling meningitis are seen. Often a bout of ...
Serologic testing using enzyme-linked immunosorbent serologic assay (ELISA) can be made afterward. Treatment consists of ... Elevated liver enzymes, leukopenia, proteinuria and thrombocytopenia, which leads to hemorrhagic fever and encephalitis (which ...
Abnormal liver function tests (randomly detected on blood tests) may be seen. Coeliac disease is associated with several other ... However, serologic tests have high sensitivity only in people with total villous atrophy and have very low ability to detect ... There are several tests that can be used. The level of symptoms may determine the order of the tests, but all tests lose their ... tTG testing should be done first as it is an easier test to perform. An equivocal result on tTG testing should be followed by ...
Although serologic tests are not specific enough for diagnostic purposes, they can be used as basic epidemiologic tools. The ... This initiates the cycle in the human liver. The ring stages that are formed by the invasion of merozoites released by ... rupturing liver stage schizonts are the first stages that appear in the blood. The ring stages grow slowly but soon fill one- ...
Sometimes serologic testing is used as supportive evidence, although no commercial serologic test is currently available. Other ... An adult worm lives and reproduces in the intestine of its definitive host, the raccoon. The female worm can produce between ... The fact that no commercial serologic test exists for the diagnosis of B. procyonis infection makes the diagnosis and treatment ... Laboratory and clinical diagnosis can be challenging: there is no commercially available serologic test in the United States, ...
Serologic testing can be helpful but should not be the sole basis for diagnosis. The Centers for Disease Control (CDC) issued a ... The gall bladder was shown to be in an abnormal position having flipped over the liver. The gallbladder was removed and the ... he was noted to have positive serologic tests for Borrelia burgdorferi. Treatment with a 14 day course of intravenous ... Upon performance of a CCK test, standard imaging techniques are done with the patient lying prone, in this instance it was done ...
Measuring of the metabolic activity of live cells (live cells staining): after incubation of target cells with antibodies and ... When potentially suitable couple is found, crossmatch test is done to exclude that patient produces donor-specific anti-HLA ... CDC form of HLA typing (other words serologic typing) uses batch of anti-HLA antibodies from characterised allogeneic antisera ... Amount of dead cells (and thus positive result) is measured by dead or live cells staining. Nowadays CDC typing is being ...
The available tests include the tube-precipitin (TP) assays, complement fixation assays, and enzyme immunoassays. TP antibody ... An indirect demonstration of fungal infection can be achieved also by serologic analysis detecting fungal antigen or host IgM ... Currently there are no completely effective preventive measures available for people who live or travel through Valley Fever - ... Inmates Should Be Tested for Valley Fever Immunity". California HealthLine. 2014-07-28. Shehab, Ziad M. (2010). " ...
Sometimes serologic testing is used as supportive evidence, although no commercial serologic test is currently available. Other ... An adult worm lives and reproduces in the intestine of its definitive host, the giant panda. The female worm can produce over ... The fact that no commercial serologic test exists for the diagnosis of B. shroederi infection makes the diagnosis and treatment ... Concern for human infection is minimal as there are very few giant pandas living today and most people do not encounter giant ...
Abnormal liver function tests (randomly detected on blood tests) may be seen.[19] ... However, serologic tests have high sensitivity only in people with total villous atrophy and have very low ability to detect ... Antibody testing may be combined with HLA testing if the diagnosis is unclear. TGA and EMA testing are the most sensitive serum ... tTG testing should be done first as it is an easier test to perform. An equivocal result on tTG testing should be followed by ...
... an available serologic test may be useful in diagnosis. Affected dogs are sometimes isolated from other dogs and their bedding ... live in follicles. In humans, these two types of mite infections, which would otherwise be known as "mange" in furry mammals, ... The test is also positive in animals with ear mites, an ear canal infection caused by a different but closely related mite ( ... Nevertheless, topical ivermectin has not been well enough tested to be approved for this use in dogs, and is theoretically much ...
There are a number of immunoassays that can aid in diagnosis, however serologic testing is available in few labs in the endemic ... which may have been contaminated by vectors Prevent young children from playing with or eating live snails Treatment of ... however due to this rarity a clinical diagnosis based on the above tests is most likely. There are public health strategies ...
... liver and kidney function tests, and serologic tests for parasitic and connective tissue diseases. The stool is often examined ... Specific test for causative conditions are performed, often including chest x-ray, urinalysis, ... and tests for serum LDH and other tumor markers.[3] ... though a negative test does not rule out parasitic infection; ...
Serologic testing looks for the presence of antibodies against the adult schistosome in the blood. This can only take place 6 ... One strain lives in the Congo area, particularly Zaire, and the other strain lives in the Lower Guinea area, mainly in Cameroon ... However, serologic testing is not useful for patients with previous infections. Praziquantel is an effective treatment against ... The schistosomulae then migrate to the hepatic portal system of the liver to mature into adults. As adults, they make their way ...
... and a positive serologic test does not necessarily distinguish between infections-up and coming serologic tests that are highly ... Adults live in the subcutaneous tissues of humans, where they mate and produce worm-like eggs called microfilariae. These ... No report on the distribution status of LIPS or QLIPS testing is available, but these tests would help to limit complications ... Whereas a previously described LISXP-1 ELISA test had a poor sensitivity (55%), the QLIPS test is both practical, as it ...
... live vector vaccine - liver function test (LFT) - long terminal repeat sequence (LTR) - long-term nonprogressors - LTR - lumbar ... serologic test - seroprevalence - serosorting - serostatus - serum - serum glutamic oxaloacetic transaminase (SGOT) - serum ... histocompatibility testing - histoplasmosis - HIV disease - HIV prevention trials network (HPTN) - HIV set point - HIV vaccine ... PPD test - pre-conception counseling - preclinical - precursor cells - prevalence - primary HIV infection - primary isolate - ...
Anti-DFS70 antibody tests are available as CE-marked tests. Until now, no FDA cleared assay is available.[48] ... Anti-Ro antibodies are also found less frequently in other disorders including autoimmune liver diseases, coeliac disease, ... "Long-term outcome in mixed connective tissue disease: Longitudinal clinical and serologic findings". Arthritis & Rheumatism ... The ANA test detects the autoantibodies present in an individual's blood serum. The common tests used for detecting and ...
Serologic tests and enzyme linked immunosorbent assays (ELISA), which measured Variola virus-specific immunoglobulin and ... It contains live vaccinia virus, cloned from the same strain used in an earlier vaccine, Dryvax. While the Dryvax virus was ... Fenner, Frank (2006). Nature, Nurture and Chance: The Lives of Frank and Charles Fenner. Canberra, ACT 0200: Australian ... Did bioweapons test cause a deadly smallpox outbreak?". Science. 296 (5576): 2116-17. doi:10.1126/science.296.5576.2116. PMID ...
PCR testing is used in conjunction with blood film examination and possibly serologic testing.[9] ... Unlike the Plasmodium parasites that cause malaria, Babesia species lack an exoerythrocytic phase, so the liver is usually not ... Serologic testing for antibodies against Babesia (both IgG and IgM) can detect low-level infection in cases with a high ... April 1994). "Diagnosis of babesiosis: evaluation of a serologic test for the detection of Babesia microti antibody". J. Infect ...
... with autoimmune hepatitis often have no initial symptoms and the disease is detected by abnormal liver function tests.[1] ... 60% of patients have chronic hepatitis that may mimic viral hepatitis, but without serologic evidence of a viral infection. The ... autoimmune disease of the liver that occurs when the body's immune system attacks liver cells causing the liver to be inflamed ... Liver transplantation may be required if patients do not respond to drug therapy or when patients present with fulminant liver ...
The Hong Kong flu was the first known outbreak of the H3N2 strain, though there is serologic evidence of H3N? infections in the ... Sixty-one influenza B viruses tested belong to the B/Yamagata lineage and are related to the vaccine strain (B/Florida/04/2006 ... Of the 97 recent H3N2 isolates examined, only 41 had strong serologic cross-reactions with antiserum to three commercial SIV ... "Serologic and genetic characterization of North American H3N2 swine influenza A viruses". Canadian Journal of Veterinary ...
Antinuclear antibody (ANA) testing and anti-extractable nuclear antigen (anti-ENA) form the mainstay of serologic testing for ... Today, over 90% now survive for more than ten years, and many live relatively symptom-free. 80-90% can expect to live a normal ... When skin not exposed to the sun is tested, a positive direct IF (the so-called lupus band test) is an evidence of systemic ... The LE cell test is rarely performed as a definitive lupus test today as LE cells do not always occur in people with SLE and ...
The diagnosis may be confirmed by a simple blood test for IgA antibodies against tissue transglutaminase (which cross-react ... and tetracyclines has been shown to be effective and well tolerated in some individuals who cannot tolerate dapsone or live in ... for a small-intenstinal biopsy if an individual has biopsy-confirmed dermatitis herpetiformis as well as supporting serologic ... Thus, for both groups of patients, it may be necessary to restart gluten for several weeks before testing may be done reliably ...
Evaluation of Altona Diagnostics RealStar Zika Virus RT-PCR Test Kit for Zika virus PCR testing» (en anglès). J Clin Microbiol ... CDC «Advice for people living in or traveling to South Florida» (en anglès). Zika Virus. Areas with Zika. Cases in the US, 2016 ... Lanciotti, RS; Kosoy, OL; Rentin, JJ; et al «Genetic and serologic properties of Zika virus associated with an epidemic, Yap ... Saá P, Proctor M, Foster G, Krysztof D, et al «Investigational Testing for Zika Virus among U.S. Blood Donors» (en anglès). N ...
Test sensitivity and specificity vary widely among the many tests reported for the serologic diagnosis of schistosomiasis and ... Eggs can also become lodged in the liver, leading to high blood pressure through the liver, enlarged spleen, the buildup of ... The worms of S. mansoni and S. japonicum migrate to the veins of the gastrointestinal tract and liver.[19] Eggs in the gut wall ... The parasite can live in the water for only 48 hours without a human host. Once a host has been found, the worm enters its ...
In the United States no serologic tests for diagnosis of HEV infection have ever been authorized by the Food and Drug ... Occasionally this may result in a life-threatening illness such as fulminant liver failure or liver cirrhosis.[23][24] ... Assuming that vaccination has not occurred, tests may show:[5] *if the person's immune system is normal, then *if IgM anti-HEV ... "Liver International. 28 (9): 1190-1199. doi:10.1111/j.1478-3231.2008.01840.x. ISSN 1478-3223. PMC 2575020. PMID 18662274.. ...
... live-attenuated) HSV vaccine are undergoing human testing.[citation needed] ... Brown ZA, Wald A, Morrow RA, Selke S, Zeh J, Corey L (2003). "Effect of serologic status and cesarean delivery on transmission ... Laboratory testing. Laboratory testing is often used to confirm a diagnosis of genital herpes. Laboratory tests include culture ... Until the 1980s serological tests for antibodies to HSV were rarely useful to diagnosis and not routinely used in clinical ...
Senadhi, V (2011 Jul). "A paradigm shift in the outpatient approach to liver function tests.". Southern medical journal 104 (7 ... Serologic profile of Homa ya nyongo C infection. Uchunguzi wa Homa ya nyongo C unaangalia yafuatayo: HCV kingamwili, ELISA, ... Boyer, JL (2001). Liver cirrhosis and its development: proceedings of the Falk Symposium 115. Springer, 344. ISBN 9780792387602 ... Ahn, J; Flamm, SL (2011 Aug). "Hepatitis C therapy: other players in the game". Clinics in liver disease 15 (3): 641-56. doi: ...
Serologic testingEdit. Serology (the measurement of virus-specific antibodies in the serum) is not frequently used in RSV ... Children living with HIV are more likely to develop acute illness, and are 3.5 times more likely to require hospitalization ... Rapid antigen detection tests (RADT) are commonly used as point-of-care testing due to their ease of use and quick turnaround ... The sensitivity of DFA testing depends on an adequate specimen.[27]. Molecular testingEdit. Molecular assays, such as nucleic ...
At the time, serologic testing was negative for viral hemorrhagic fever. She was discharged on January 19, 2008. After the ... "Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses". Nature Medicine. 11 (7): 786 ... Many candidate vaccines have been developed and tested in various animal models.[40][41][42][43][44][45][46] Of those, the most ... "Cross-Protection against Marburg Virus Strains by Using a Live, Attenuated Recombinant Vaccine". Journal of Virology. 80 (19 ...
The liver is involved in most cases, but function tests are normal or mildly abnormal. Granulomas (B. abortus), hepatitis (B. ... The sensitivity of the ELISA was 100% when compared with blood culture, but only 44% compared with serologic tests other than ... In the laboratory, biochemical tests can be diagnostic. Oxidase and catalase tests are positive for most members of the genus ... PCR testing for fluid and tissue samples other than blood has also been described. A history of animal contact is pivotal; in ...
... causes and effects of a disease on a specific population on the basis of serologic tests) in Egypt was the first to show the ... Heller, L.; Humez, A.; Dror, M. (1984). The Private Lives of Words (1st ed.). Abingdon, UK: Routledge & Kegan Paul. pp. 58-9. ... The grayish violet, crescent-like spleen weighs less than 500 g (18 oz).[43] The triangular, four-chambered liver weighs 6.5 kg ... Hegazi, A.H. (1954). "The liver of the camel as revealed by macroscopic and microscopic examinations". American Journal of ...
Senadhi, V (2011 Jul)। "A paradigm shift in the outpatient approach to liver function tests."। Southern medical journal। 104 (7 ... Serologic profile of Hepatitis C infection. হেপাটাইসিস সি নির্ণয়ের পরীক্ষাগুলোর মধ্যে রয়েছেঃ এইচসিভি অ্যান্টিবডি, ইএলআইএসএ, ... Boyer, JL (২০০১)। Liver cirrhosis and its development: proceedings of the Falk Symposium 115। Springer। পৃষ্ঠা 344। আইএসবিএন ... Maheshwari, A (2010 Feb)। "Management of acute hepatitis C."। Clinics in liver disease। 14 (1): 169-76; x। PMID 20123448।. ...
In contrast to serologic tests reporting a direct blood type phenotype, genotyping allows the prediction of a phenotype based ... are usually administered to patients who have a potentially fatal clotting problem caused by a condition such as advanced liver ... In addition to the current practice of serologic testing of blood types, the progress in molecular diagnostics allows the ... "Blood group test, Gentest.ch". Gentest.ch GmbH. Retrieved 2006.. Check date values in: ,accessdate=. (help). ...
IG Living (February-March 2015): 28-32. Archived (PDF) from the original on 27 October 2015. Retrieved 23 November 2015.. ... "Laboratory Serologic Problems Associated with Administration of Intravenous IgG". Current Issues in Transfusion Medicine. he ... In the later 1990s, large-scale trials began in Europe to test the feasibility of subcutaneous immunoglobulin administration, ... Immunoglobulin therapy also interferes with the ability of the body to produce a normal immune response to an attenuated live ...
Although little serologic data exist, the prevalence of infection is thought to be highest among blacks living in the Southeast ... HIV testing should also be performed, as some patients may be co-infected with both viruses.[citation needed] Allogenic bone ...
All living surfaces are decorated with a diverse range of complex molecules, which are key modulators of chemical ... Chesla, S; Henry, S; Eatz, R; Sinor, L (2010). "Solid phase syphilis test utilizing KODE technology". Transfusion. 50: 196A- ... Henry, Stephen; Perry, Holly (2012). FSL-A+B(tri) Serologic Teaching Kit Technical Bulletin. Scholarly Commons. hdl:10292/2827 ... Constructs insert into living or fixed cell (glutaraldehyde) membranes. Simple FSL peptide synthesis - there is a reactive- ...
Leukopenia and abnormal liver function tests are commonly seen in the early phase of the illness. Pneumonitis, encephalitis, ... 2007). "Scrub typhus serologic testing with the indirect immunofluorescence method as a diagnostic gold standard: a lack of ... The cheapest and most easily available serological test is the Weil-Felix test, but this is notoriously unreliable. The gold ... since the serological test involved is not included in the routine screening tests for PUO, especially in Burma (Myanmar).[ ...
Strain differences in amebae used for antigen and for inoculation could not be detected by either test. The IHA test appeared ... 128 and above were indicative of liver infections in the experimentally infected hamsters. ... There was fair correlation between size of liver lesion and titers. ... Abstract Results of testing 298 sera from hamsters inoculated in the liver with Entamoeba histolytica and from 25 uninoculated ...
It should be noted that both tests are recommended only as an adjunct to the clinical diagnosis; the results are not specific ... George Y Wu, MD, PhD is a member of the following medical societies: American Association for the Study of Liver Diseases, ... What are the limitations of serologic testing to differentiate between ulcerative colitis and Crohn disease?. Updated: Jul 26, ... It should be noted that both tests are recommended only as an adjunct to the clinical diagnosis; the results are not specific ...
Serologic testing. Other causes of liver disease can usually be excluded through history taking, examination and serologic ... of potential live liver donors undergoing liver biopsy.3 Ultrasonography detects fatty changes in the liver in 12.9%-16.4% of ... Findings on liver biopsy to investigate abnormal liver function tests in the absence of diagnostic serology. J Hepatol 2001;35: ... Liver biopsy performed on patients who have persistently elevated liver enzyme levels and no viral serologic markers of chronic ...
Amebic liver abscess is the most frequent extraintestinal manifestation of Entamoeba histolytica infection. This infection is ... Serologic testing. Serologic testing is the most widely used method of diagnosis for amebic liver abscess. In general, the test ... Similar complete blood cell (CBC) count and liver test abnormalities are found in patients with pyogenic liver abscesses and ... of patients with amebic liver abscess. Under these circumstances, order repeat serology testing in 1 week. This test result ...
The Widal test was the mainstay of t... more ... Efficacy of a live oral typhoid vaccine in human volunteers. ... What specific serologic tests are used in the diagnosis of typhoid fever (enteric fever)?. Updated: Aug 19, 2019 ... The Widal slide agglutination test, a valuable rapid diagnostic test in typhoid fever patients at the Infectious Diseases ... The Widal test was the mainstay of typhoid fever diagnosis for decades. It is used to measure agglutinating antibodies against ...
5.5 Live Attenuated Virus Vaccines 5.6 Interference with Serologic Testing 5.7 Transmissible Infectious Agents 6 ADVERSE ... may interfere with serologic tests for red cell antibodies such as the antiglobulin test (Coombs test). ... 5.6 Interference with Serologic Testing *A transient rise of the various passively transferred antibodies in the patients ... Individual plasma units are tested using FDA-licensed serologic assays for hepatitis B surface antigen (HBsAg) and for ...
5.5 Live Attenuated Virus Vaccines 5.6 Interference with Serologic Testing 5.7 Transmissible Infectious Agents 6 ADVERSE ... may interfere with serologic tests for red cell antibodies such as the antiglobulin test (Coombs test). ... 5.6 Interference with Serologic Testing *A transient rise of the various passively transferred antibodies in the patients ... Individual plasma units are tested using FDA-licensed serologic assays for hepatitis B surface antigen (HBsAg) and for ...
Serologic Testing for HBV Infection. Testing unvaccinated HCP for HBV infection is not generally indicated for persons being ... of those who become chronically infected after childhood die prematurely from cirrhosis or liver cancer (1,15). An estimated ... Certain institutions test vaccinated HCP by measuring anti-HBs upon hire or matriculation, even when anti-HBs testing occurs ... ACIP also recommends that vaccinated HCP receive postvaccination serologic testing (antibody to hepatitis B surface antigen [ ...
Guidelines for HCV-RNA testing & liver fibrosis. Take Quiz. Guidelines: HCV tests & interpreting the results. Take Quiz. ... ADA guidelines: Testing for prediabetes & type 2 diabetes. Take Quiz. Type 2 diabetes: Risk factors & predispositions. Take ... ADA guidelines: Testing for prediabetes & type 2 diabetes. Take Quiz. Type 2 diabetes: Risk factors & predispositions. Take ... NIAID Guidelines: Infant peanut allergy testing & prevention. Take Quiz. Thyroid dysfunction: USPSTF recommendations. Take Quiz ...
Serologic Tests * Smoking / adverse effects * Social Class * Surveys and Questionnaires * Switzerland / epidemiology ... Objective: The authors tested the hypothesis that children growing up on a farm were less likely to be sensitized to common ... Prevalence of hay fever and allergic sensitization in farmers children and their peers living in the same rural community. ... Materials and methods: Three age groups of schoolchildren (6-7 years, 9-11 years, 13-15 years) living in three rural ...
No serum samples had evidence of neutralizing antibodies when tested against rabies virus. However, 16 samples had detectable ... Serologic Testing. All 394 serum samples were negative against RABV, but 16 (4%) were positive or suggestive of ABLV (Table 2 ... No additional bats died after the procedure, according to residents living near roosts. ... Serologic Testing for Neutralizing Antibodies. Serum specimens were obtained from blood samples after clotting. In general, 394 ...
Serologic testing, radiological imaging and histological analysis can help diagnose SSC. First lines of treatment can include ... If these fail a liver transplant may be necessary. Abdalian R, Heathcote EJ (November 2006). "Sclerosing cholangitis: a focus ... Secondary sclerosing cholangitis (SSC) is a chronic cholestatic liver disease. SSC is a sclerosing cholangitis with a known ... and possibly a liver transplant. SSC is thought to develop as a consequence of known injuries or pathological processes of the ...
Immunity Proven by Serologic Testing. Blood antibody titer, a blood test, may be used to indicate immunity to measles, mumps, ... Live Rubella: 1 injection required.. Documented History of Illness. If diagnosed by a physician, nurse practitioner, or ... Documentation can be through proof of vaccine history, documented history or illness, or immunity proven by serologic testing. ... Live Measles: 2 doses required. Vaccines must have been administered at least 28 days apart. ...
Liver Enzymes. It is recommended that liver function tests be performed before the initiation of Zocor, and thereafter when ... Additional neuromuscular and serologic testing may be necessary. Treatment with immunosuppressive agents may be required. ... No evidence of mutagenicity was observed in a microbial mutagenicity (Ames) test with or without rat or mouse liver metabolic ... It is recommended that liver function tests be performed before the initiation of treatment, and thereafter when clinically ...
Available diagnostic tests are aimed at detection of the virus, its antigenic components, or the host immune antibody response ... Very specific for alphaviruses; gold standard for confirmation of serologic test results. Requires the use of live virus ( ... Other factors influencing test choice include the purpose of testing and availability of resources. Each type of test offers ... tests that screen for these viruses simultaneously are preferred to test for them separately. CHIKV and DENV are not readily ...
Liver Enzymes. It is recommended that liver enzyme tests be performed before the initiation of PRAVACHOL, and thereafter when ... Additional neuromuscular and serologic testing may be necessary. Treatment with immunosuppressive agents may be required. ... Laboratory Abnormalities: liver function test abnormalities, thyroid function abnormalities.. Laboratory Test Abnormalities. ... It is recommended that liver function tests be performed prior to the initiation of therapy and when clinically indicated. ...
Immunity Proven by Serologic Testing. Blood antibody titer, a blood test may be used to indicate immunity to measles, mumps, ... regarding meningitis and students living in Residence Hall, and requires all students who will be living in Residence Hall be ... Live Rubella: 1 injection required.. Documented History of Illness. If diagnosed by a physician, nurse practitioner, or ... Live Measles: 2 doses required. Vaccines must have been administered at least 28 days apart. ...
Serologic testing also may be helpful. Additional information and diagnostic assistance (serologic, parasitologic, and ... Saving Lives, Protecting People Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting ... In CE, the lesions are cystic (referred to as hydatid cysts) and most commonly develop in the liver; the next most common site ... AE usually affects the liver; direct extension to (and destruction) of contiguous tissues may occur, as may metastatic lesions. ...
Behavioral assessments (by audio computer assisted self interviewing) and blood draws (for serologic testing) occur at baseline ... Liver Diseases. Digestive System Diseases. Hepatitis, Viral, Human. Virus Diseases. Flaviviridae Infections. RNA Virus ... Prior to study enrollment, all participants in both arms receive HIV and HCV testing with client-centered pre- and post-test ... 3285 participants completed the baseline visit, of whom 1564 tested HIV and HCV seronegative and returned for test results ...
The liver is responsible for many critical processes and a damaged liver is unable to do this efficiently. We look at the ... Liver disease is any condition which damages the liver, impairing its function. ... Serologic Testing: Testing for diseases such as FeLV, FIV, FIP, and toxoplasmosis may be taken as these diseases are associated ... What is liver disease? Symptoms Diagnosis Treatment Prevention. Feline liver disease at a glance:. About: Liver disease is ...
Serologic analysis can be also used - ELISA test for IgG antibodies against antigens of M. conjunctus. Drugs used to treat ... It lives in the bile duct and in the gallbladder. M. conjunctus causes a disease called metorchiasis. It has been known to ... Also, higher concentrations of liver enzymes are seen. When untreated, symptoms may last from 3 days to 4 weeks. Symptoms of ... Watson T. G & Croll N. A. (1981). "Clinical changes caused by the liver fluke Metorchis conjunctus in cats". Veterinary ...
The right lobe of the liver harbored the cysts in the maximum number of patients. Surgery was the preferred modality of ... The hydatid cyst of the liver is a common cause of morbidity in Nepal. Clinical evaluation supplemented by imaging studies is ... Abdominal pain (49, 92.5%) and a palpable liver (17, 32.1%) were the most common complaint and physical finding in our study ... and management of the patients of the hydatid cyst of the liver in the setting of a developing country. It was a retrospective ...
Liver. Other activities to help include hangman, crossword, word scramble, games, matching, quizes, and tests. ... Dx of amebic liver abscess?. Serologic testing (IgG immunoassay) establishes diagnosis. Stool antigen test not sensitive. LFTs ... MC type of benign liver tumor. Cavernous hemangioma. Diagnostic test of choice in cavernous hemangioma? Which diagnostic test ... MC location for hyatid liver cysts?. right lobe of liver. Tx for hyatid liver cysts?. Surgical resection with mebendazole post- ...
Frequently, immune serum markers are present; they include autoantibodies against liver-specific and non-liver-specific ... The development of viral serologic tests represented another important step forward. These tests permitted hepatologists to ... Recurrence of autoimmune liver diseases after liver transplantation. World J Hepatol. 2015 Dec 18. 7(29):2896-905. [Medline]. ... Michitaka K, Nishiguchi S, Aoyagi Y, et al, for the Japan Etiology of Liver Cirrhosis Study Group. Etiology of liver cirrhosis ...
May need serologic testing to ensure adequate antibody response for immunization;b additional doses of the vaccine or toxoid ... Concurrent administration of live virus vaccines in patients receiving immunosuppressive doses of corticosteroids.g ... The dexamethasone suppression test for the detection, diagnosis, and managemnt of depression. Ann Intern Med. 1984; 100:307-8. ... Live virus vaccines contraindicated in individuals receiving immunosuppressive hydrocortisone dosesc. Defer routine ...
Mucinous cystic neoplasms of the liver and extrahepatic biliary tree have recently been re-defined by WHO as epithelial cystic ... Serologic tests will confirm the diagnosis [28].. Liver abscess initially is seen as a cluster of small foci that later ... Endometriosis in the liver. Mucinous cystic tumour of the liver. Oestrogen receptors. + stroma//+ epithelium. + stroma//− ... Cystic neoplasms of the liver are rare while simple liver cysts are common, seen in 2.5-18% of population [54]. Radiological ...
Serologic testing. * Serum albumin Serum albumin. Albumin is a protein made by the liver. A serum albumin test measures the ... Leishmania-specific PCR test. * Liver biopsy and culture Liver biopsy. A liver biopsy is a test that takes a sample of tissue ... Other tests that may be done include:. * Complete blood count Complete blood count. A complete blood count (CBC) test measures ... Tests that may be done to diagnose the condition include:. * Biopsy of the spleen and culture Biopsy. A biopsy is the removal ...
An ACTH stimulation test to rule out hypoadrenocorticism (Addisons disease). *Bile acids tests if liver disease was identified ... Serologic tests for certain infectious diseases that may cause melena. * ... An extensive battery of tests is often required to identify or isolate the specific cause, and such tests may include:. *A ... To determine the exact cause of melena in dogs, additional tests are usually necessary and include the following:. *Complete ...
Suggested Additional Lab Testing. Acute hepatitis C. *. Elevated liver function tests are expected with positive tests for anti ... False-positive serologic test for hepatitis C. ... Positive Serologic Test for Hepatitis C Virus (HCV). *By. * ...
The reference method for the serologic diagnosis of leptospirosis is the microscopic agglutination test (MAT).2,4,17 To perform ... the MAT is a complex test that relies on the maintenance of live cultures of several leptospiral serovars.4 These cultures may ... Chappel RJ, Goris M, Palmer MF, Hartskeerl RA. Impact of proficiency testing on results of the microscopic agglutination test ... We chose to test for the most common serogroups of leptospirosis that are believed to infect dogs in North America. The 7 ...
  • With the ELISA technique, it was tentatively concluded that titers of 1:32 were specific for anti-amebic antibodies but only those of 1:128 and above were indicative of liver infections in the experimentally infected hamsters. (ajtmh.org)
  • The EIA test detects antibodies specific for E histolytica in approximately 95% of patients with extraintestinal amebiasis, in 70% of patients with active intestinal infection, and in 10% of persons who are asymptomatic cyst passers. (medscape.com)
  • No serum samples had evidence of neutralizing antibodies when tested against rabies virus. (cdc.gov)
  • Serologic analysis can be also used - ELISA test for IgG antibodies against antigens of M. conjunctus. (wikipedia.org)
  • High rate of positive anti-tissue transglutaminase antibodies in chronic liver disease. (semanticscholar.org)
  • The aim of the study was to compare the behaviour of anti-tTG and anti-endomysium antibodies assays in coeliacs and in patients with chronic liver disease. (semanticscholar.org)
  • No remarkable hematologic or serologic abnormalities were observed, nor were negative antibodies to COVID-19. (healio.com)
  • Serologic tests for syphilis, with the detection of nontreponemal antibodies (cardiolipin) or antibodies against T. pallidum in all stages of infection, remain the mainstay of diagnosis ( 1 , 2 ). (asm.org)
  • however, these blood tests only indicate the presence of antibodies known to be prevalent in individuals with celiac disease. (aapc.com)
  • They found that TV003, a live attenuated dengue vaccine that induces antibodies to all four dengue virus serotypes, protected against infection of an attenuated virus in 21 recipients when compared with 20 nonvaccinated controls. (sciencemag.org)
  • Serologic testing detects various antibodies produced by the body against Ehrlichia. (petplace.com)
  • Serologic studies for antibodies to E histolytica are supportive. (renalandurologynews.com)
  • Your recent nonspecific reactivity (indeterminate) Western Blot following a reactive (positive) HIV 1 and HIV 2 antibody screening test most likely is due to nonspecific cross-reacting antibodies possibly induced by your previous pregnancies. (thebody.com)
  • however, it can be helpful in sorting out unclear or indeterminate HIV-antibody test results, as it does not rely on anti-HIV antibodies, but rather checks for a piece of the HIV virus itself. (thebody.com)
  • Pregnancy can cause false-positive ELISA tests and indeterminate Western Blot results due to cross-reacting antibodies. (thebody.com)
  • Serologic testing for antibodies is available, but a positive result does not necessarily indicate an active case of onchocerciasis. (medic8.com)
  • In serologic studies conducted in the United States during the 1970s, HCP had a prevalence of HBV infection approximately 10 times greater than the general population ( 1 ). (cdc.gov)
  • The purpose of this study is to test whether a six-session behavioral intervention for HIV and HCV seronegative injection drug users is effective in reducing sexual and injection risk behaviors that could lead to primary HIV and HCV infection. (clinicaltrials.gov)
  • Cholangitis relates to infection or inflammation of the bile duct and cholangiohepatitis is inflammation of the biliary system and by extension the liver. (cat-world.com.au)
  • Caused by intracellular protozoa known as Toxoplasma gondii, most infected cats will show no symptoms of infection, however in some cases damage to various organs can occur, including the liver. (cat-world.com.au)
  • Cirrhosis secondary to hepatitis C virus (HCV) infection, alone or in combination with alcohol, is the principal indication for liver transplantation among adults, and is responsible for about half the transplants performed in many centres. (bmj.com)
  • Some facts about HCV infection and liver transplantation have been substantiated since the end of 1998. (bmj.com)
  • There is no uniform definition of recurrent hepatitis C and this has impaired interpretation of results of different studies, despite an increasing interest in the evaluation of the natural history of HCV infection in liver transplant patients. (bmj.com)
  • The number of Canadians living with HIV infection continues to increase. (canada.ca)
  • Approximately 30% of people living with HIV infection are unaware of their HIV status. (canada.ca)
  • Infection may spread by direct extension from the liver to the right lung and pleural space or, rarely, through the bloodstream to the brain and other organs. (merckmanuals.com)
  • Extraintestinal amebic disease originates from infection in the colon and can involve any organ, but a liver abscess is the most common. (merckmanuals.com)
  • However, the researchers wrote that, "The clinical, histologic and laboratory test results were compatible with a diagnosis of perniosis, and no evidence was found to support the implication of SARS-CoV-2 infection. (healio.com)
  • Inclusion did not depend on the results of serologic testing for previous C. pneumoniae infection. (aafp.org)
  • Nontreponemal tests (NTT) are largely used to monitor the status of infection, while treponemal tests (TT) are primarily used to confirm the presence of treponemal infection. (asm.org)
  • The sensitivity and specificity of both TT and NTT vary with the type of test as well as the stage of syphilis infection. (asm.org)
  • Animals currently quarantined are being tested for serologic evidence of Ebola virus infection. (cdc.gov)
  • Positive real-time polymerase chain reaction (RT-PCR) tests for current SARS-CoV-2 infection - not antibody or antigen tests - must be reported to the Alameda County Public Health Department (ACPHD). (acphd.org)
  • Polymorphisms in the immune response genes can contribute to clearance of hepatitis C virus (HCV) infection but also mediate liver inflammation and cancer pathogenesis. (frontiersin.org)
  • Selected PDCD1, IFNL3, and TLR2 genes were tested by molecular approaches in 450 HCV-positive patients with increasing severity of underlying liver diseases [including chronic infection (CHC), cirrhosis and hepatocellular carcinoma (HCC)], in 238 HCV-positive patients with lymphoproliferative diseases [such as cryoglobulinemia and non-Hodgkin lymphoma (NHL)] and in 94 blood donors (BD). (frontiersin.org)
  • Hepatocellular carcinoma is the primary malignancy of the liver that often occurs in the setting of underlying chronic liver disease, mostly HBV and/or C virus infection (HBV and HCV, respectively), alcoholic liver disease, and non-alcoholic fatty liver disease. (frontiersin.org)
  • mostly related to the increase of HCV infection acquired before the availability of the serologic test. (frontiersin.org)
  • One person had worked with animals infected with live virus, but it is uncertain how the other person acquired the infection (4,5). (cdc.gov)
  • On the basis of historical information, as well as serologic testing, sporadic Lassa infection may have occurred also in Guinea, Senegal, Mali, and the Central African Republic (6,7). (cdc.gov)
  • Infection with this organism may present as intestinal amoebiasis, eg amoebic colitis or may be manifested extra-intestinally as hepatic amoebiasis, amoebic liver or brain abscess. (ebscohost.com)
  • Of the mass of returning military and Peace Corps personnel, most will have been exposed to amebic infection and thousands will harbor the disease within the liver in a subclinical state. (ebscohost.com)
  • It is sometimes difficult to determine whether the antibody titers present in the dog are due to chronic exposure to the disease because the dog lives in areas where infected ticks are prevalent, or whether the titers indicate there is active infection present in the dog. (petplace.com)
  • A positive diagnosis of infection was made if any 1 of the specimens tested positive and were confirmed in a second PCR assay targeting independent genes. (swipnet.se)
  • A serosurvey among 40 other Dinosaur National Monument workers did not find serologic evidence of recent infection. (cdc.gov)
  • Patients at high risk for hepatitis B infection should be evaluated with hepatitis serologic tests. (renalandurologynews.com)
  • A number of diagnostic methods and assays have been described for the detection of YFV infection, including viral culture, molecular testing, serology, and antigen detection. (asm.org)
  • Only 15% of U.S. veterans have been tested for hepatitis B virus (HBV) infection, and among those who tested HBsAg positive just one-quarter received antiviral treatment and 13% were screened for liver cancer -- although both measures were shown to reduce the risk of death -- researchers reported Sunday at the American Association for the Study of Liver Diseases (AASLD) Liver Meeting in Boston. (hivandhepatitis.com)
  • HBV and HCV infection were confirmed by serologic and/or virologic test and categorized as ever, never infected, or missing. (natap.org)
  • 10 The virus travels from the site of infection to the regional lymph nodes, liver, spleen, and adrenal glands. (uspharmacist.com)
  • Serum samples were evaluated by HCV serologic testing and polymerase chain reaction (PCR) assay [4]. (annals.org)
  • Ehrlichia polymerase chain reaction (PCR) is a test that is capable of detecting the presence of extremely small amounts of the parasite. (petplace.com)
  • In this article we discuss the etiology, pathogenesis and diagnosis of nonalcoholic fatty liver disease as well as approaches to its management. (cmaj.ca)
  • The diagnosis of nonalcoholic fatty liver disease (NAFLD) requires evidence of fatty changes in the liver in the absence of a history of excessive alcohol consumption. (cmaj.ca)
  • Serologic testing is the most widely used method of diagnosis for amebic liver abscess. (medscape.com)
  • What specific serologic tests are used in the diagnosis of typhoid fever (enteric fever)? (medscape.com)
  • The Widal test was the mainstay of typhoid fever diagnosis for decades. (medscape.com)
  • It was a retrospective, descriptive analysis of 53 patients admitted in the department of surgery with the diagnosis of hydatid cyst of the liver based on clinical manifestations, imaging studies, or serology between 2016 and 2019. (hindawi.com)
  • The microscopic agglutination test (MAT) is commonly used for the diagnosis of canine leptospirosis. (wiley.com)
  • The MAT is a valuable test for the diagnosis of leptospirosis in dogs, but it is unlikely that test results can be used to predict the infecting serogroup. (wiley.com)
  • Diagnosis is by identifying E. histolytica in stool specimens or by serologic tests. (merckmanuals.com)
  • liver biopsy for diagnosis? (thebody.com)
  • While direct tests (e.g., microscopy or PCR) are helpful in early syphilis, the mainstay of diagnosis remains serologic tests. (asm.org)
  • This article reviews current tests and discusses current controversies in syphilis diagnosis, with a focus on serologic tests. (asm.org)
  • This article discusses older tests as well as recent advances in the diagnosis of syphilis with a focus on current testing algorithms for syphilis as well as point-of-care tests (POCT). (asm.org)
  • Diagnosis should be confirmed by isolation, identification, and serotyping of S enterica Gallinarum ( National Poultry Improvement Plan testing procedure). (merckvetmanual.com)
  • Amebiasis should be considered in the differential diagnosis of diarrhea, dysentery, colitis, liver abscess (and rarely liver abscess extending to the pleura or pericardia), or brain abscess. (renalandurologynews.com)
  • Approach to diagnosis and serologic testing is centered on the. (wellchild.org)
  • To conduct a study in a small rural hospital located in the state of Chiapas, Mexico, to: (1) examine the prevalence of chagasic cardiomyopathy among patients with the diagnosis of congestive heart failure and (2) assess the prevalence of positive serologic results in blood donors in the hospital, in an attempt to ascertain whether Chagas' disease remains an important cause of heart failure at least in some areas of Mexico. (scielosp.org)
  • Hepatic steatosis detected by magnetic resonance spectroscopy is found in 31% of adults in the United States 2 and in 33% of potential live liver donors undergoing liver biopsy. (cmaj.ca)
  • 4 , 10 , 11 Obesity, diabetes and the metabolic syndrome are also risk factors for NASH and for advanced fibrosis on liver biopsy. (cmaj.ca)
  • Urgent liver biopsy, transjugular if appropriate, may help to confirm the clinical suspicion of acute autoimmune hepatitis. (medscape.com)
  • A liver biopsy is a test that takes a sample of tissue from the liver for examination. (stlukes-stl.com)
  • I know that biopsy is used to assess degree of damage to the liver. (thebody.com)
  • However, in the event of serologic test negatives for viral hepatitis but sustained raised ALTS and other symptoms, can the liver biopsy be used to actually diagnose viral hepatitis? (thebody.com)
  • If they are negative, liver biopsy can still be useful to diagnose other liver diseases than viral hepatitis like PBC, autoimmune hepatitis, etc. (thebody.com)
  • Non-invasive Markers of Liver Fibrosis: Adjuncts or Alternatives to Liver Biopsy? (frontiersin.org)
  • Whilst the presence of mild fibrosis on biopsy can be a reassuring finding, the identification of advanced fibrosis is critical to the management of patients with chronic liver disease. (frontiersin.org)
  • This necessity has lead to a reliance on liver biopsy which itself is an imperfect test and poorly accepted by patients. (frontiersin.org)
  • Should a liver biopsy be required, the appropriateness is clearer and the diagnostic yield is greater with the use of these adjuncts. (frontiersin.org)
  • Historically, the role of liver biopsy was both for diagnostic and staging purposes. (frontiersin.org)
  • Given the ability to diagnose the majority of liver conditions with blood testing alone, liver biopsy now primarily serves to quantify fibrosis in order to stage disease. (frontiersin.org)
  • Liver biopsy represents the "gold standard" for the assessment and quantification of liver fibrosis. (frontiersin.org)
  • you can talk to the doctor about forgoing the biopsy and diagnosing based on blood tests alone, or just wait for the biopsy, but he's right in keeping her on gluten for that in order for it to be a reliable test. (celiac.com)
  • Serum samples were collected from three patients with biopsy proven liver metastasis secondary to uveal melanoma (patient 1,2, 3), one patient with uveal melanoma without clinical evidence of metastasis (patient 4), and one patient with uveal melanoma and cutaneous metastasis without clinical evidence of liver metastasis (patient 5). (arvojournals.org)
  • Disease presentation ranges from asymptomatic elevated liver enzyme levels to cirrhosis with complications of liver failure and hepatocellular carcinoma. (cmaj.ca)
  • 1 2 This may mean that a subset of the approximately 300 million people worldwide infected with HCV will progress to cirrhosis, liver failure, and would need a transplant in the future. (bmj.com)
  • CIC levels were not significantly different in the three different liver diseases studied (acute hepatitis, chronic hepatitis and liver cirrhosis). (biomedsearch.com)
  • It is a common cause of cirrhosis and hepatocellular carcinoma (HCC) as well as the most common reason for liver transplantation. (nih.gov)
  • Cirrhosis is chronic, end-stage liver disease in which normal liver tissue has been replaced by fibrous scar tissue. (pethealthnetwork.com)
  • When cirrhosis occurs, scar tissue replaces functioning liver cells. (pethealthnetwork.com)
  • Cirrhosis occurs as a result of damage to the liver by many diseases, drugs, or toxins. (pethealthnetwork.com)
  • Common diseases that may lead to cirrhosis include cancer as well as viral, bacterial, and fungal infections that cause hepatitis (inflammation of the liver). (pethealthnetwork.com)
  • Additionally, diagnostic tests will be required to identify if your cat has cirrhosis of the liver. (pethealthnetwork.com)
  • Treatment for your cat will vary depending on the underlying cause of the liver damage and cirrhosis. (pethealthnetwork.com)
  • The most effective prevention of cirrhosis is to address liver disease as early as possible and maintain your cat's preventive health care to avoid any situation that may cause liver disease. (pethealthnetwork.com)
  • Up to one in five sufferers develop liver cirrhosis, and up to one in 20 develop liver cancer. (bio-medicine.org)
  • however should the source of liver injury persist, fibrosis may progress, and ultimately evolve to cirrhosis or end-stage liver disease. (frontiersin.org)
  • Nearly 40% had a record of significant alcohol use and 8.3% had diagnosed liver cirrhosis. (hivandhepatitis.com)
  • Only 13% of HBsAg positive patients overall, and 18% of those in specialty care, were screening for hepatocellular carcinoma (HCC, a type of primary liver cancer), as recommended for people with active hepatitis B, especially those with cirrhosis (these figures excluded people under age 50 -- as HCC usually occurs in older people with long-term disease progression -- though many experts believe younger at-risk people should be screened as well). (hivandhepatitis.com)
  • How long must a pt abstain for alcohol before being considered for liver transplantation? (studystack.com)
  • Liver transplantation also may be used to rescue patients who present with fulminant hepatic failure secondary to autoimmune hepatitis. (medscape.com)
  • 8 Definitions based on biochemical or serological markers may be inaccurate as altered liver function tests in the transplant patients clearly lack specificity, 6 7 and serological assays 17 18 are relatively insensitive, both before and after transplantation. (bmj.com)
  • Available options in patients with unresectable HCC are liver transplantation, percutaneous ethanol injection, radiofrequency ablation, and transcatheter arterial chemoembolization ( Hernaez and El-Serag, 2018 ). (frontiersin.org)
  • HCV is the top reason for liver transplantation, and the 16th leading cause of premature death in the country. (bio-medicine.org)
  • In acute liver abscess, the aspartate aminotransferase (AST) levels are high. (medscape.com)
  • Liver disease can be acute (sudden onset) or chronic (slow and progressive). (cat-world.com.au)
  • Some patients go on to develop signs and symptoms of chronic liver disease, while others rapidly progress to acute liver failure, as marked by coagulopathy and jaundice. (medscape.com)
  • We present a patient with an acute amebic liver abscess with nonreactive serologic tests. (ebscohost.com)
  • Available diagnostic tests are aimed at detection of the virus, its antigenic components, or the host immune antibody response. (hindawi.com)
  • To enhance the knowledge of medical society on the mucinous cystic neoplasms of the liver, here we aim to summarise contemporary data on these tumours, including the current definition and classification [ 1 ], the recent molecular genetic findings [ 3 , 4 ] as well as the practical issues of clinical presentation, diagnostic approach, treatment and prognosis. (intechopen.com)
  • The presence of melena generally warrants hospitalization, extensive diagnostic testing, and supportive care. (petplace.com)
  • While recent advances in molecular methods such as PCR look promising ( 3 ), this test largely remains a research tool as it is still not available in many diagnostic laboratories. (asm.org)
  • While there is active transmission of SARS-CoV-2 in Alameda County, ACPHD recommends that facilities, medical, and dental providers implement policies and strategies that include screening of all patients for symptoms of COVID-19 and selective preprocedural testing of patients undergoing non-emergent surgical, dental, or diagnostic procedures that may involve intubation or the generation of biological aerosols. (acphd.org)
  • If the patient returned with consistent or worsening symptoms, the physician might've ordered a diagnostic test, such as endoscopy. (aapc.com)
  • Based on the negative results of the diagnostic testing (nothing would show up because the inflammation is in the intestine), the physician would likely diagnose the patient with dyspepsia and recommend he or she continue on antacids. (aapc.com)
  • Similar complete blood cell (CBC) count and liver test abnormalities are found in patients with pyogenic liver abscesses and are not specific. (medscape.com)
  • 7 g/dL) with slight abnormalities in liver normal vasculature, including telangiectases function tests. (who.int)
  • Livers of young K8 or K8/K18 overexpressors had no histological abnormalities despite increased keratin protein and phosphorylation. (rupress.org)
  • The patient subsequently died, and an autopsy revealed diffuse large-cell lymphoma that was positive for EBV latent membrane protein 1 in both liver and kidney specimens. (meds.com)
  • However, the utility of this test is limited by the inability of even experienced observers to distinguish the organism from other, nonpathogenic treponemes in some specimens ( 1 ). (asm.org)
  • Specimens reactive by pan-immunoglobulin (pan Ig) enzyme linked immunosorbent assay (ELISA) against the full spike protein were tested by IgG and IgM ELISAs, microneutralization test, Ortho total Ig S1 ELISA, and receptor binding domain / Ace2 blocking activity assay. (nexopia.com)
  • Of these 106 specimens, 90 were available for further testing. (nexopia.com)
  • Results of testing 298 sera from hamsters inoculated in the liver with Entamoeba histolytica and from 25 uninoculated controls by indirect hemagglutination (IHA) and enzyme linked immunosorbent assay (ELISA) showed that measurable amounts of antibody appeared as early as 5 days after inoculation, generally increased to a high level within 20 days, and persisted for the duration of the experiments (58 days). (ajtmh.org)
  • E histolytica galactose lectin antigen is detectable by enzyme-linked immunosorbent assay (ELISA) in at least 75% of serum samples obtained from patients with amebic liver abscess. (medscape.com)
  • Serologic testing was done in both groups with either indirect hemagglutination (IHA) or enzyme-linked immunosorbent assay (ELISA), or with both. (scielosp.org)
  • The prevalence of celiac disease among patients with non-alcoholic fatty liver disease in Iran. (semanticscholar.org)
  • Comparison of commercially available serologic kits for the detection of celiac disease. (semanticscholar.org)
  • What is the role of serologic testing in celiac disease? (semanticscholar.org)
  • Two blood vessels enter the liver, the hepatic portal vein contains de-oxygenated blood from the spleen, pancreas, and digestive system and the hepatic artery contains oxygen-rich blood from the lungs. (cat-world.com.au)
  • Your health care provider will examine you and may find that your spleen, liver, and lymph nodes are enlarged. (stlukes-stl.com)
  • Lesions in older birds include swollen, friable, bile-stained and necrotic lesions in the liver, in addition to enteritis and enlargement of the spleen and kidneys. (merckvetmanual.com)
  • The portal system carries blood from the intestines, pancreas, and spleen to the liver. (thefreelibrary.com)
  • Although within normal limits in many cases, they may reveal an enlarged liver or spleen. (petplace.com)
  • Tissue samples of approximately 0.5 g of liver and spleen were homogenized with 0.9 ml of phosphate-buffered saline (PBS) using the FastPrep™-system (QBiogene, Heidelberg, Germany). (biomedcentral.com)
  • What are the limitations of serologic testing to differentiate between ulcerative colitis and Crohn disease? (medscape.com)
  • NONALCOHOLIC FATTY LIVER DISEASE is emerging as the most common chronic liver condition in the Western world. (cmaj.ca)
  • In general, the test result should be positive, even in cases when the result of the stool test is negative (only extraintestinal disease). (medscape.com)
  • Secondary sclerosing cholangitis (SSC) is a chronic cholestatic liver disease. (wikipedia.org)
  • New York State Law 2167 requires institutions, including colleges and universities, to distribute information about meningococcal disease and vaccination to all students-undergraduate, graduate and visiting-meeting the enrollment criteria, whether they live on or off campus. (iona.edu)
  • Please note: Iona College adheres to the recommendations of the Centers for Disease Control (CDC) regarding meningitis and students living in Residence Hall, and requires all students who will be living in Residence Hall be immunized prior to move in day. (iona.edu)
  • Saving Lives, Protecting People Centers for Disease Control and Prevention. (cdc.gov)
  • Liver disease is defined as any condition which damages the liver, which leads to an inability to perform many of its vital functions. (cat-world.com.au)
  • There are a number of causes of liver disease including ingestion of toxins, fatty liver disease, portosystemic shunt, tumours, and toxoplasmosis. (cat-world.com.au)
  • Also known as hepatic disease , liver disease is a collection of diseases all of which result in damage to the liver leading to impaired function. (cat-world.com.au)
  • Cats of any age can develop liver disease. (cat-world.com.au)
  • Hepatic Lipidosis is the most common type of liver disease in the cat and occurs when your cat becomes anorexic (stops or reduces the amount of food he is eating), the body begins to use fat stores as fuel. (cat-world.com.au)
  • The second most common form of liver disease which is caused by a number of related inflammatory and or infectious disorders of the liver and/or the biliary tract. (cat-world.com.au)
  • A hydatid cyst of the liver (HCL), a disease most commonly caused by a tapeworm Echinococcus granulosus, is a significant yet neglected public health problem in developing nations like Nepal [ 1 ]. (hindawi.com)
  • Which classification is used to estimate hepatic reserve in liver failure: measures disease severity, and is predictor of morbidity and mortality? (studystack.com)
  • Which Child's class indicates milder liver disease? (studystack.com)
  • Most severe liver disease? (studystack.com)
  • Indicates end-stage liver disease. (studystack.com)
  • The first is that the patients were in the early stage of disease, which might explain the negative PCR and serologic tests. (healio.com)
  • Patients were excluded from participation if they had allergy to macrolide antibiotics, were pregnant or lactating, were using drugs containing ergotamine or dihydroergotamine, had severe systemic disease (i.e., liver disease, central nervous system disease) that could keep them from adhering to the study protocol, or had a possible inability to complete follow-up. (aafp.org)
  • Do the authors suggest that all elderly patients with elevated liver enzyme levels be screened for Wilson disease? (annals.org)
  • In a retrospective study, we investigated serum samples of 2815 inpatients and outpatients with suspected liver disease from whom samples were obtained every 3 or 6 months for at least 2 years. (annals.org)
  • However a new species of Campylobacter , C hepaticus , has been identified as the cause of spotty liver disease in layer chickens. (merckvetmanual.com)
  • C hepaticus is the species associated with spotty liver disease of layers and breeder chickens and may be the etiological agent of the disease formerly known as avian vibrionic hepatitis. (merckvetmanual.com)
  • The standard serologic tests for Pullorum disease also detect fowl typhoid. (merckvetmanual.com)
  • Development of ascites is predictive of mortality, especially in liver disease. (thefreelibrary.com)
  • The increased pressure occurs due to fibrosis and scarring of the liver from chronic liver disease, causing obstruction to venous flow (Whiteman & McCormick, 2005). (thefreelibrary.com)
  • A careful history of the patient with ascites should include information that places a patient at risk for liver disease, including quantity and duration of alcohol use, transfusion of blood products, and personal or family history of autoimmune or hepatic diseases. (thefreelibrary.com)
  • The test-based strategy, previously described as an option for ending isolation, should no longer be considered except in very specific circumstances and after consultation with an infectious disease expert. (acphd.org)
  • 1 - 3 Cerebral infestation by EM and EG differ: AE occurs in adults who live in rural areas, whereas hydatid disease affects mostly children. (ajnr.org)
  • however, neither written information about her medical history nor a report of pathologic examination about her liver disease was available. (ajnr.org)
  • Providers may also administer immunoglobulin to adults older than 40 years of age, if indicated, and persons who are immunocompromised or have chronic liver disease. (cdc.gov)
  • The hepatitis C virus (HCV) is one of the leading known causes of liver disease in the United States. (nih.gov)
  • Specter was right when he said we need a test that shows what stage of disease you are at, but it's not that simple. (lymedisease.org)
  • The most common single indication for liver disease, or tumors can be drawn with the european heart rhythm at this time period should be the target organs renal tubule, bone, or both can present with a counselor to express a few minutes to a pediatric oncology protocols for citrate anticoagulation have been normal for the family, and the addition of extra tutoring may be rv dependent. (visitmayberry.com)
  • Nucleic acid testing for the disease. (visitmayberry.com)
  • It also allows the in-vestigator to study the distribution of added adipose tissue may deform the valves in the fields of neonatal presentation, and a history of rheumatic fever, endocarditis, and kawasaki disease, systemic lupus erythematosus, vasculitis, and coagulation tests may be indistinguishable from primary ovarian failure occur in patients with std risk factors. (visitmayberry.com)
  • If normal liver function falls below 20%, the disease becomes terminal. (pethealthnetwork.com)
  • The relatively young age of persons dying from hepatitis C-related liver disease has made hepatitis C-related disease a leading infectious cause of years of potential life lost as well as an important cause of premature mortality overall," the authors concluded. (bio-medicine.org)
  • The development of robust tools to non-invasively assess liver fibrosis has dramatically enhanced clinical decision making in patients with chronic liver disease, allowing a rapid and informed judgment of disease stage and prognosis. (frontiersin.org)
  • Compared to the standard two-tiered testing (STTT) algorithm for Lyme disease serology using an enzyme immunoassay (EIA) followed by Western blotting, data from the United States suggest that a modified two-tiered testing (MTTT) algorithm employing two EIAs has improved sensitivity to detect early localized Borrelia burgdorferi infections without compromising specificity. (medworm.com)
  • From 2011 to 2014, in the Canadian province of Nova Scotia, where Lyme disease is hyperendemic, sera submitted for Lyme disease testing were subjected to a whole-cell EIA, followed by C6 EIA and subsequently IgM and/or IgG immunoblots on sera with EIA-pos. (medworm.com)
  • Documentation can be through proof of vaccine history, documented history or illness, or immunity proven by serologic testing. (iona.edu)
  • Neither sensitive nor specific, the Widal test is no longer an acceptable clinical method. (medscape.com)
  • The present study was carried out to evaluate the demographic characteristics, clinical presentations, and management of the patients of the hydatid cyst of the liver in the setting of a developing country. (hindawi.com)
  • Little progress has been made in the area of serologic diagnostics for congenital syphilis, which requires assessment of maternal treatment and serologic response as well as clinical and laboratory investigation of the neonate for appropriate management. (asm.org)
  • Presents two cases illustrating the clinical features of amebic colitis, complicated by liver abscess. (ebscohost.com)
  • This review will summarize and appraise the current and novel non-invasive markers of liver fibrosis, both blood and imaging based, and look at their prospective application in everyday clinical care. (frontiersin.org)
  • ACIP also recommends that vaccinated HCP receive postvaccination serologic testing (antibody to hepatitis B surface antigen [anti-HBs]) 1-2 months after the final dose of vaccine is administered (CDC. (cdc.gov)
  • Out of 16,718,682 individuals with at least 2 visits to VA health facilities, a total of 2,533,862 -- or 15% -- had a record of being tested for hepatitis B surface antigen (HBsAg). (hivandhepatitis.com)
  • Approximately three fourths of patients with an amebic liver abscess have leukocytosis. (medscape.com)
  • In chronic liver abscess, the alkaline phosphatase level tends to be elevated and the AST level tends to be within the normal limits. (medscape.com)
  • Overall, the alkaline phosphatase level is elevated in about 70% of cases of amebic liver abscess. (medscape.com)
  • [ 17 ] and the lack of intestinal amebiasis in as many as 60% of patients with amebic liver abscess. (medscape.com)
  • Initial negative test results may appear in as many as 10% of patients with amebic liver abscess. (medscape.com)
  • Travelers can also acquire amebic infections, which may cause dysentery or, in some instances, liver abscess. (aafp.org)
  • Simultaneous amoebic caecal perforation and amoebic liver abscess rupture is a rare complication of invasive amoebiasis with a higher rate of mortality. (ebscohost.com)
  • Amoebic liver abscess rupture always needs some form of drainage. (ebscohost.com)
  • We report a rare case of amoebic caecal perforation with ruptured liver abscess. (ebscohost.com)
  • Of 23 sera from patients with proven amebic liver abscess. (ebscohost.com)
  • Treatment of Amebic Abscess of the Liver. (ebscohost.com)
  • Presents a study which discussed the treatment of amebic abscess of the liver. (ebscohost.com)
  • Advice to patients suspected of having a liver abscess. (ebscohost.com)
  • An amebic liver abscess may remain silent for months or years. (ebscohost.com)
  • Simultaneous Amebic Liver Abscess and Hepatitis A. Orenstein, Walter A. (ebscohost.com)
  • A child with amebic colitis, liver abscess and hepatitis A is reported. (ebscohost.com)
  • Abdominal pain or cough can be symptoms if there is a liver abscess, which is a rare complication in children (most common in young men). (renalandurologynews.com)
  • The most feared outcome is development of an amebic liver abscess, which is rare in children. (renalandurologynews.com)
  • An amebic liver abscess can extend to the pleural or pericardial spaces and rarely result in hematogenous dissemination to the brain. (renalandurologynews.com)
  • In contrast, amebic liver abscess is most common in men between the ages of 20 and 40 years. (renalandurologynews.com)
  • The authors tested the hypothesis that children growing up on a farm were less likely to be sensitized to common aerollergens and to suffer from allergic diseases than children living in the same villages but in nonfarming families. (nih.gov)
  • [ 2 ] The American Association for the Study of Liver Diseases (AASLD) and the British Society of Gastroenterology (BSG) recommend combination therapy, using the corticosteroid prednisone with azathioprine. (medscape.com)
  • The skin is tested to look for skin conditions or diseases. (stlukes-stl.com)
  • Immune complex levels and HBs-antigenaemia in healthy Nigerians and patients with liver diseases. (biomedsearch.com)
  • Circulating immune complexes (CIC) were precipitated and assayed in the blood of 19 adult patients with liver diseases and 39 healthy adult Nigerians. (biomedsearch.com)
  • Keratins 8 and 18 (K8/18) are major constituents of Mallory bodies (MBs), which are hepatocyte cytoplasmic inclusions seen in several liver diseases. (rupress.org)
  • K8 overexpression is sufficient to form pre-MB and primes animals to accumulate MBs upon DDC challenge, which may help explain MB formation in human liver diseases. (rupress.org)
  • A rapid antigen-detection dipstick test using monoclonal antibody to the histidine-rich protein 2 of P. falciparum is available, but it is not helpful in diagnosing malaria caused by other Plasmodium species. (aafp.org)
  • Direct tests like PCR and antigen detection at one time held promise, but people attacked them for being "contaminated" or they argued that the positive was caused by debris, not living organisms. (lymedisease.org)
  • The liver plays a central role in lipid metabolism, importing serum free fatty acids and manufacturing, storing and exporting lipids and lipoproteins. (cmaj.ca)
  • 20 Hyperinsulinemia increases serum free fatty acid levels, which are taken up by the liver and drive triglyceride production and hepatic steatosis ( Fig. 1 ). (cmaj.ca)
  • A serum albumin test measures the amount of this protein in the clear liquid portion of the blood. (stlukes-stl.com)
  • Serum immunoelectrophoresis is a lab test that measures proteins called immunoglobulins in the blood. (stlukes-stl.com)
  • Laboratory tests showed lymphopenia, normal serum viscosity, and a stable IgM level. (meds.com)
  • The dendrite is a failure to fully expand the alveolus, called type ii is 0.4mg tamsulosin familiar with the underlying condition is often common bacterial, viral, fungal, bacterial, and mycobacterial skin tests, serum calcium levels. (visitmayberry.com)
  • The objective of this study was to identify novel serum proteins whose levels of expression may be associated with liver metastasis secondary to UM using two-dimensional gel electrophoresis coupled with tandem mass spectrometry. (arvojournals.org)
  • We have identified several protein bands of interest that occurred more frequently in serum from patients with liver metastasis secondary to uveal melanoma. (arvojournals.org)
  • The liver changes ammonia, a toxic by-product of protein metabolism into urea, which is excreted in the urine. (cat-world.com.au)
  • Elevations in kidney and/or liver values, elevated or decreased protein levels in the blood, and protein in the urine may also be found. (petplace.com)
  • Use of a leishmanin skin test in the detection of canine Leishmania -specific cellular immunity. (ajtmh.org)
  • Results from this retrospective pilot study, Dr. Wolf said, suggest that the lymphocyte/ white blood cell count ratio could be used as a quickly available alternative test for the detection of mononucleosis. (medpagetoday.com)
  • Molecular detection of Borrelia burgdorferi in free-living golden headed lion tamarins (Leontopithecus chrysomelas) in Rio de Janeiro, Brazil. (medworm.com)
  • 3 Ultrasonography detects fatty changes in the liver in 12.9%-16.4% of individuals. (cmaj.ca)
  • Patients with a test that detects co can con-firm endotracheal tube with a. (nrha.org)
  • Serologic and virologic studies of animals and workers are under way in these and other facilities in the Philippines. (cdc.gov)
  • Under these circumstances, order repeat serology testing in 1 week. (medscape.com)
  • Behavioral assessments (by audio computer assisted self interviewing) and blood draws (for serologic testing) occur at baseline, 3 and 6 month follow-up. (clinicaltrials.gov)
  • Congenital malformations do occur in up to seven percent of all live births. (rxlist.com)
  • Tenderness over the liver or ascending colon may occur, and stools may contain mucus and blood. (merckmanuals.com)
  • Hydatid cysts occur in the liver in 75% and in the lungs in 15% of cases. (springer.com)
  • The liver is the only organ in the body that is capable of regenerating itself and has an amazing functional reserve with up to 70% of the functional mass impaired before symptoms may present. (cat-world.com.au)
  • Even when the test showed intact, whole spirochetes, you might be denied treatment because "there is no proof that they are causing the symptoms. (lymedisease.org)
  • A hydatid cyst of the liver is a significant yet neglected public health problem in Nepal. (hindawi.com)
  • The hydatid cyst of the liver is a common cause of morbidity in Nepal. (hindawi.com)
  • In patients diagnosed with a hydatid cyst, imaging methods and serologic tests are very important for identifying cranial involvement. (springer.com)
  • People living with HIV (PWH) are often co-infected with HBV and HCV, leading to increased risk of hepatocellular carcinoma (HCC). (natap.org)
  • Its unique position and vascular supply also leaves it constantly exposed to potential injury, and liver damage, induced by hepatotoxins such as viral hepatitis, alcohol or excess fat, leads to a cycle inflammation and fibrosis. (frontiersin.org)
  • Blood antibody titer, a blood test may be used to indicate immunity to measles, mumps, and rubella. (iona.edu)
  • A complete blood count (CBC) test measures the following:The number of red blood cells (RBC count)The number of white blood cells (WBC count)The tota. (stlukes-stl.com)
  • This form, common in the tropics, manifests with episodes of frequent semiliquid stools that often contain blood, mucus, and live trophozoites. (merckmanuals.com)
  • Amebic dysentery, common in the tropics, manifests with episodes of frequent semiliquid stools that often contain blood, mucus, and live trophozoites. (merckmanuals.com)
  • One hundred forty-nine persons who came in contact with infected animals or the blood or tissues of these animals were placed under surveillance for 21 days after their last known exposure, and all were tested for Ebola virus antibody. (cdc.gov)
  • Routine blood tests revealed mild leukocytosis with a white blood cell count of 14,600. (ajnr.org)
  • Packed red blood cells sweat test and not transcribed, c. (nrha.org)
  • Blood HCV RNA copies were assayed with Roche - COBAS® AmpliPrep/COBAS® TaqMan® HCV Test. (clinicaltrials.gov)
  • This method usually involves follow-up blood tests to monitor the patient's response to a gluten-free diet. (aapc.com)
  • All patients were given the mononucleosis spot test, as well as a lymphocyte and overall white blood cell count, from which the L/WCC ratio was calculated. (medpagetoday.com)
  • Why would you want to go to a blood specialist to find out about an abnormal HIV test ? (thebody.com)
  • I have just found out today that my 4-year-old daughter has test positive for Celiac (the antibody blood test). (celiac.com)
  • With the blood donors, the results of their serologic screening were reviewed for a six-month period beginning in April 2002. (scielosp.org)
  • Small mammals were decoyed and live-trapped with Sherman traps [ 8 ], ectoparasites were combed off and - where possible - blood samples were collected by heart-puncture under anaesthesia. (biomedcentral.com)
  • The stool examination is still of value if the serologic and antigen identification tests are not available. (medscape.com)
  • The PCR stool test shows high sensitivity for detecting E histolytica and for distinguishing nonpathogenic amoebas. (medscape.com)
  • El estudio de los pacientes con miocardiopatía se llevó a cabo mediante la inspección retrospectiva de las fichas de pacientes con un diagnóstico de insuficiencia cardíaca congestiva tratados en el hospital durante el período de 2000-2002. (scielosp.org)
  • En el caso de los donantes de sangre, los resultados de sus pruebas serológicas fueron revisados durante un período de seis meses que comenzó en abril de 2002. (scielosp.org)
  • An Ebola-related filovirus was isolated from liver tissue of one of these animals. (cdc.gov)
  • One hundred eighty-one collected sera were tested for amebic serologic reactivity, using the counterelectrophoresis technic (CEP) and compared to the results of the agar gel diffusion (AGD) and the latex agglutination (LA) methods. (ebscohost.com)
  • Live Rubella: 1 injection required. (iona.edu)
  • BIAVAX (rubella and mumps virus vaccine live) ® II ( Rubella and Mumps Virus Vaccine Live) is a live virus vaccine for immunization against rubella ( German measles ) and mumps. (rxlist.com)
  • The vaccine viruses are the same as those used in the manufacture of MERUVAX* II (Rubella Virus Vaccine Live) and MUMPSVAX* (Mumps Virus Vaccine Live). (rxlist.com)
  • BIAVAX (rubella and mumps virus vaccine live) II is indicated for simultaneous immunization against rubella and mumps in persons 12 months of age or older. (rxlist.com)
  • Previously unimmunized children of susceptible pregnant women should receive live attenuated rubella vaccine , because an immunized child will be less likely to acquire natural rubella and introduce the virus into the household. (rxlist.com)
  • and if single-antigen measles vaccine is not readily available, travelers should receive M-M-R II (Measles, Mumps, and Rubella Virus Vaccine Live) regardless of their immune status to mumps or rubella. (rxlist.com)
  • Immunization of susceptible non-pregnant adolescent and adult females of childbearing age with live attenuated rubella virus vaccine is indicated if certain precautions are observed (see below and PRECAUTIONS ). (rxlist.com)
  • It is recommended that rubella susceptibility be determined by serologic testing prior to immunization. (rxlist.com)
  • If immune, as evidenced by a specific rubella antibody titer of 1:8 or greater (hemagglutination-inhibition test), vaccination is unnecessary. (rxlist.com)
  • The steatotic liver is then thought to be vulnerable to secondary insults, which lead to hepatocellular inflammation and fibrosis. (cmaj.ca)
  • In wolves, M. conjunctus causes cholangiohepatitis with periductular fibrosis in the liver. (wikipedia.org)
  • Liver fibrosis reflects sustained liver injury often from multiple, simultaneous factors. (frontiersin.org)
  • While a number of non-invasive liver fibrosis markers are now used in routine practice, a steady stream of innovative approaches exists. (frontiersin.org)
  • 95% homologous by DNA-DNA hybridization ( 4 ) and are indistinguishable on serologic testing. (asm.org)
  • If you have a positive antibody test and you live in an area where Lyme is uncommon, or if your doctor just "thinks" it's a false positive, you won't be treated. (lymedisease.org)
  • There are multiple strains and even species of Borrelia for which there are no specific tests, and scientists are discovering new ones all the time. (lymedisease.org)
  • In Sheth and colleagues' review of NASH [1] , the authors advocate extensive evaluation of patients with unexplained elevations in liver enzyme levels. (annals.org)
  • Liver enzyme levels will be elevated in these cases. (renalandurologynews.com)
  • Pre-vaccination serologic testing is not required to administer hepatitis A vaccine. (cdc.gov)
  • Human efficacy testing remains a major hurdle in bringing new vaccine candidates to the clinic. (sciencemag.org)
  • TV003 is a live attenuated tetravalent DENV vaccine currently in phase 2 evaluation. (sciencemag.org)
  • The authors describe a 53-year-old woman with no known immunodeficiency who presented with diffuse pruritic rash 17 days after receiving the varicella virus vaccine live. (jaoa.org)
  • Since varicella virus vaccine live became available in the United States in 1995, more than 55 million doses have been distributed. (jaoa.org)
  • 1 , 7 Localized rash is the most common adverse event reported in patients receiving the varicella virus vaccine live. (jaoa.org)
  • Previously undiagnosed immunodeficiencies that were revealed after severe vaccine reactions have been reported in patients receiving live vaccines. (jaoa.org)
  • Nearly 48 million doses of the varicella virus vaccine live were distributed between 1995 and 2005, and the Vaccine Adverse Events Reporting System reported 8262 cases of rash, of which 197 cases (2.4%) were classified as serious. (jaoa.org)
  • 2 Other analyses of adverse events associated with VZV vaccination have come from the Worldwide Adverse Experience System managed by Merck & Co, Inc, the manufacturer of Varivax (ie, varicella virus vaccine live). (jaoa.org)
  • We describe a case of a woman who presented with a diffuse pruritic rash 17 days after receiving the varicella virus vaccine live. (jaoa.org)
  • A 53-year-old woman presented to the emergency department (ED) with a diffuse pruritic rash 17 days after receiving the varicella virus vaccine live. (jaoa.org)
  • A recent equine study compared killed and MLV equine herpes virus type 1 (EHV-1) vaccines, and found the MLV vaccine offered superior protection when tested by aerosol challenge. (equinewellnessmagazine.com)
  • The most commonly ordered test - ELISA - is based on a strain from Long Island, NY. (lymedisease.org)
  • Since Novemeber, I have had one ELISA test which read an inconclusive result, and two Western Blot Tests that both came back inconclusive as well. (thebody.com)
  • Los pruebas serológicas se efectuaron en ambos grupos mediante hemaglutinación indirecta (HAI) o ensayo de inmunoadsorción enzimática (ELISA), o ambos métodos. (scielosp.org)
  • The metacestode spreads from the inevitably involved liver to other organs such as the lungs and brain and bone by infiltration and metastasis. (ajnr.org)
  • Arterial venous malformations may found in the lungs, brain and liver [3,4]. (who.int)
  • Fecal findings suggestive of amebic colitis include a positive test for heme, a paucity of neutrophils, and the presence of Charcot-Leyden crystal protein. (medscape.com)
  • This test result will usually be positive. (medscape.com)
  • Elevated liver function tests are expected with positive tests for anti-HCV by a variety of methods. (neurologyadvisor.com)
  • An antemortem serologic test was positive for EBV (data not shown). (meds.com)
  • There has been a 20% rise in the number of positive HIV test reports in Canada in the last 5 years (2000-2004). (canada.ca)
  • however, the heterosexual exposure category represents a growing number and proportion of positive HIV tests, surpassing injection drug use (IDU) as the second largest exposure category. (canada.ca)
  • Persons migrating to Canada from countries where HIV is endemic also represent an increasing proportion of the positive HIV test reports in the last 3 years. (canada.ca)
  • Women represent an increasing proportion of those with positive HIV test reports, as well as reported AIDS cases in Canada. (canada.ca)
  • Over 25% of the positive HIV test reports in 2004 were in women, compared to less than 10% prior to 1995. (canada.ca)
  • Aboriginal peoples make up a growing percentage of positive HIV test reports and reported AIDS cases. (canada.ca)
  • Nearly 50% of all positive HIV test reports among Aboriginal Canadians were in women (less than 20% of positive HIV test reports among Caucasian Canadians were in women). (canada.ca)
  • Aboriginal peoples test positive for HIV at a younger age compared to non-Aboriginal persons. (canada.ca)
  • Heterosexual exposure accounts for more than 80% of positive HIV test reports in this group. (canada.ca)
  • Approximately 50% of positive HIV test reports in this group are in women. (canada.ca)
  • The interpretation of syphilis tests is further complicated by the lack of a reliable gold standard for syphilis diagnostics, and the newer tests can result in false-positive reactions similar to those seen with older tests. (asm.org)
  • Even a positive test is no guarantee you will receive treatment. (lymedisease.org)
  • I tested positive in 2005 for anti hiv 1 and 2. (thebody.com)
  • A positive initial anti-HIV-1/HIV-2 test followed by negative supplemental tests, including Western Blot and p24 antigen is a negative HIV test. (thebody.com)
  • If in the very unlikely case you test positive for both the supplemental HIV tests and confirmatory Western Blot, you should then be evaluated by an HIV specialist. (thebody.com)
  • Among those who were tested, 21,828 individuals -- or 0.9% -- were found to be HBsAg positive. (hivandhepatitis.com)
  • People who died within 1 week of receiving a positive HBsAg test were excluded from further analysis. (hivandhepatitis.com)
  • None of the ticks or fleas (n = 432) tested positive for F. tularensis . (biomedcentral.com)
  • The large red dot indicates the water sample tested positive for F. tularensis . (biomedcentral.com)
  • Decreased pth or pth effecthypoparathyroidism is seen when inferior vena cava by the underlying liver failure, and neurologic concussions, uncontrolled seizures. (nrha.org)
  • One-third had alanine aminotransferase (ALT) levels at least twice the upper limit of normal, suggesting active liver inflammation. (hivandhepatitis.com)
  • the employee shows serologic evidence of immunity. (ihs.gov)
  • avoid other live attenuated vaccines within 3 months. (oncologynurseadvisor.com)
  • In other countries, vaccines (killed or modified live) made from a rough strain of S enterica Gallinarum (9R) had variable results in controlling mortality. (merckvetmanual.com)
  • This article summarizes the current issues about equine vaccines - and the alternative of titer testing. (equinewellnessmagazine.com)
  • Safe and effective MLV (modified live) equine vaccines have more recently become available. (equinewellnessmagazine.com)
  • But another recent study comparing killed, MLV, and live-chimera West Nile Virus (WNV) vaccines found 100% protection with all three types following challenge with virulent WNV. (equinewellnessmagazine.com)
  • The right lobe of the liver harbored the cysts in the maximum number of patients. (hindawi.com)
  • This would prevent unnecessary requests for the slower expensive mononucleosis spot tests and facilitate the use of appropriate treatment and possibly shorter hospital stays. (medpagetoday.com)
  • While the AASLD and other professional groups have established guidelines for testing, care, and treatment, studies suggest these are not routinely followed. (hivandhepatitis.com)
  • In addition, we report results of a serologic survey of Dinosaur National Monument employees performed to assess recent exposure to C. immitis . (cdc.gov)
  • EIA has now largely replaced indirect hemagglutination (IHA) testing and counter immunoelectrophoresis (CIE) testing. (medscape.com)
  • 3285 participants completed the baseline visit, of whom 1564 tested HIV and HCV seronegative and returned for test results making them eligible to enroll in the intervention trial. (clinicaltrials.gov)
  • The expensive mononucleosis spot test at St. George's Hospital can take up to 48 hours after admission for the results to become available. (medpagetoday.com)
  • In addition, the researchers wrote, the spot test can produce false-negative results, and the test's true sensitivity should be determined by Epstein-Barr-specific serologic tests. (medpagetoday.com)
  • 3 inconclusive test results. (thebody.com)
  • Before this pregnancy, my hiv test results always came back negative with no problem. (thebody.com)
  • Serologic testing, radiological imaging and histological analysis can help diagnose SSC. (wikipedia.org)
  • Test of choice to diagnose pt with hematemesis? (studystack.com)
  • Metorchis conjunctus, common name Canadian liver fluke, is a species of trematode parasite in the family Opisthorchiidae. (wikipedia.org)
  • Abdominal pain (49, 92.5%) and a palpable liver (17, 32.1%) were the most common complaint and physical finding in our study population, respectively. (hindawi.com)
  • We tested Evan (he's 26# at 3 and 34.5") and his was negative which is more common this age, than a +, especially since he's only eaten gluten for about 1/2 his life. (celiac.com)
  • Uveal melanoma is the most common intraocular malignancy with a propensity for liver metastasis. (arvojournals.org)
  • they include autoantibodies against liver-specific and non-liver-specific antigens and increased immunoglobulin G (IgG) levels. (medscape.com)
  • Gahbauer, m chronic cough interferes with nerve root irritation crossed straight-leg raise test result subsequent colonoscopy with mucosal and systemic coagulase-negative staphylococcal infections of skin, hair, and delayed hepatic and splenic flexure or rectosig-moid junction are destroyed. (nrha.org)