Chondroblastoma: A usually benign tumor composed of cells which arise from chondroblasts or their precursors and which tend to differentiate into cartilage cells. It occurs primarily in the epiphyses of adolescents. It is relatively rare and represents less than 2% of all primary bone tumors. The peak incidence is in the second decade of life; it is about twice as common in males as in females. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1846)Curettage: A scraping, usually of the interior of a cavity or tract, for removal of new growth or other abnormal tissue, or to obtain material for tissue diagnosis. It is performed with a curet (curette), a spoon-shaped instrument designed for that purpose. (From Stedman, 25th ed & Dorland, 27th ed)Foot Bones: The TARSAL BONES; METATARSAL BONES; and PHALANGES OF TOES. The tarsal bones consists of seven bones: CALCANEUS; TALUS; cuboid; navicular; internal; middle; and external cuneiform bones. The five metatarsal bones are numbered one through five, running medial to lateral. There are 14 phalanges in each foot, the great toe has two while the other toes have three each.Bone Cysts, Aneurysmal: Fibrous blood-filled cyst in the bone. Although benign it can be destructive causing deformity and fractures.Temporal Bone: Either of a pair of compound bones forming the lateral (left and right) surfaces and base of the skull which contains the organs of hearing. It is a large bone formed by the fusion of parts: the squamous (the flattened anterior-superior part), the tympanic (the curved anterior-inferior part), the mastoid (the irregular posterior portion), and the petrous (the part at the base of the skull).Bone Neoplasms: Tumors or cancer located in bone tissue or specific BONES.Femoral NeoplasmsTarsal Bones: The seven bones which form the tarsus - namely, CALCANEUS; TALUS; cuboid, navicular, and the internal, middle, and external cuneiforms.Skull Neoplasms: Neoplasms of the bony part of the skull.Humerus: Bone in humans and primates extending from the SHOULDER JOINT to the ELBOW JOINT.Giant Cell Tumor of Bone: A bone tumor composed of cellular spindle-cell stroma containing scattered multinucleated giant cells resembling osteoclasts. The tumors range from benign to frankly malignant lesions. The tumor occurs most frequently in an end of a long tubular bone in young adults. (From Dorland, 27th ed; Stedman, 25th ed)Shoulder Fractures: Fractures of the proximal humerus, including the head, anatomic and surgical necks, and tuberosities.Bone Cysts: Benign unilocular lytic areas in the proximal end of a long bone with well defined and narrow endosteal margins. The cysts contain fluid and the cyst walls may contain some giant cells. Bone cysts usually occur in males between the ages 3-15 years.Arthrodesis: The surgical fixation of a joint by a procedure designed to accomplish fusion of the joint surfaces by promoting the proliferation of bone cells. (Dorland, 28th ed)Ilizarov Technique: A bone fixation technique using an external fixator (FIXATORS, EXTERNAL) for lengthening limbs, correcting pseudarthroses and other deformities, and assisting the healing of otherwise hopeless traumatic or pathological fractures and infections, such as chronic osteomyelitis. The method was devised by the Russian orthopedic surgeon Gavriil Abramovich Ilizarov (1921-1992). (From Bull Hosp Jt Dis 1992 Summer;52(1):1)ArchivesBiological Science Disciplines: All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.PubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.Osteoblastoma: A benign, painful, tumor of bone characterized by the formation of osteoid tissue, primitive bone and calcified tissue. It occurs frequently in the spine of young persons. (From Dorland, 27th ed; Stedman, 25th ed)Directories as Topic: Lists of persons or organizations, systematically arranged, usually in alphabetic or classed order, giving address, affiliations, etc., for individuals, and giving address, officers, functions, and similar data for organizations. (ALA Glossary of Library and Information Science, 1983)Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)Neuropsychiatry: A subfield of psychiatry that emphasizes the somatic substructure on which mental operations and emotions are based, and the functional or organic disturbances of the central nervous system that give rise to, contribute to, or are associated with mental and emotional disorders. (From Campbell's Psychiatric Dictionary, 8th ed.)Otolaryngology: A surgical specialty concerned with the study and treatment of disorders of the ear, nose, and throat.Dissection: The separation and isolation of tissues for surgical purposes, or for the analysis or study of their structures.Faculty, Medical: The teaching staff and members of the administrative staff having academic rank in a medical school.Practice (Psychology): Performance of an act one or more times, with a view to its fixation or improvement; any performance of an act or behavior that leads to learning.Educational Measurement: The assessing of academic or educational achievement. It includes all aspects of testing and test construction.Synovitis, Pigmented Villonodular: Outgrowths of synovial membrane composed of villi and fibrous nodules characterized histologically by hemosiderin- and lipid-containing macrophages and multinucleated giant cells. It usually occurs in the knee.Hearing Loss, Unilateral: Partial or complete hearing loss in one ear.Mastoid: The posterior part of the temporal bone. It is a projection of the petrous bone.Ear Canal: The narrow passage way that conducts the sound collected by the EAR AURICLE to the TYMPANIC MEMBRANE.Tenosynovitis: Inflammation of the synovial lining of a tendon sheath. Causes include trauma, tendon stress, bacterial disease (gonorrhea, tuberculosis), rheumatic disease, and gout. Common sites are the hand, wrist, shoulder capsule, hip capsule, hamstring muscles, and Achilles tendon. The tendon sheaths become inflamed and painful, and accumulate fluid. Joint mobility is usually reduced.Temporomandibular Joint: An articulation between the condyle of the mandible and the articular tubercle of the temporal bone.Acromioclavicular Joint: The gliding joint formed by the outer extremity of the CLAVICLE and the inner margin of the acromion process of the SCAPULA.Rotator Cuff: The musculotendinous sheath formed by the supraspinatus, infraspinatus, subscapularis, and teres minor muscles. These help stabilize the head of the HUMERUS in the glenoid fossa and allow for rotation of the SHOULDER JOINT about its longitudinal axis.Veronica: A plant genus of the family Plantaginaceae. Members contain bis-sesquiterpene and iridoid glucosides.Suture Anchors: Implants used in arthroscopic surgery and other orthopedic procedures to attach soft tissue to bone. One end of a suture is tied to soft tissue and the other end to the implant. The anchors are made of a variety of materials including titanium, stainless steel, or absorbable polymers.Scapula: Also called the shoulder blade, it is a flat triangular bone, a pair of which form the back part of the shoulder girdle.DislocationsLigaments, Articular: Fibrous cords of CONNECTIVE TISSUE that attach bones to each other and hold together the many types of joints in the body. Articular ligaments are strong, elastic, and allow movement in only specific directions, depending on the individual joint.Antigens, CD274: An inhibitory B7 antigen that has specificity for the T-CELL receptor PROGRAMMED CELL DEATH 1 PROTEIN. CD274 antigen provides negative signals that control and inhibit T-cell responses and is found at higher than normal levels on tumor cells, suggesting its potential role in TUMOR IMMUNE EVASION.Receptors, Tumor Necrosis Factor, Member 25: A tumor necrosis factor receptor subtype with specificity for TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15. It is found in tissues containing LYMPHOCYTES and may play a role in regulating lymphocyte homeostasis and APOPTOSIS. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.Programmed Cell Death 1 Receptor: An inhibitory T-lymphocyte receptor that has specificity for CD274 ANTIGEN and PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN. Signaling by the receptor limits T cell proliferation and INTERFERON GAMMA synthesis. The receptor also may play an essential role in the regulatory pathway that induces PERIPHERAL TOLERANCE.Receptors, TNF-Related Apoptosis-Inducing Ligand: Tumor necrosis factor receptor family members that are widely expressed and play a role in regulation of peripheral immune responses and APOPTOSIS. The receptors are specific for TNF-RELATED APOPTOSIS-INDUCING LIGAND and signal via conserved death domains that associate with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.Programmed Cell Death 1 Ligand 2 Protein: A costimulatory B7 antigen that has specificity for the T-CELL receptor PROGRAMMED CELL DEATH 1 RECEPTOR. It is closely-related to CD274 antigen; however, its expression is restricted to DENDRITIC CELLS and activated MACROPHAGES.Caspase 10: A long pro-domain caspase that contains a death effector domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS. Caspase 10 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.Apoptosis Regulatory Proteins: A large group of proteins that control APOPTOSIS. This family of proteins includes many ONCOGENE PROTEINS as well as a wide variety of classes of INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS such as CASPASES.HungaryAccess to Information: Individual's rights to obtain and use information collected or generated by others.Journal Impact Factor: A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Peer Review, Research: The evaluation by experts of the quality and pertinence of research or research proposals of other experts in the same field. Peer review is used by editors in deciding which submissions warrant publication, by granting agencies to determine which proposals should be funded, and by academic institutions in tenure decisions.Complex Regional Pain Syndromes: Conditions characterized by pain involving an extremity or other body region, HYPERESTHESIA, and localized autonomic dysfunction following injury to soft tissue or nerve. The pain is usually associated with ERYTHEMA; SKIN TEMPERATURE changes, abnormal sudomotor activity (i.e., changes in sweating due to altered sympathetic innervation) or edema. The degree of pain and other manifestations is out of proportion to that expected from the inciting event. Two subtypes of this condition have been described: type I; (REFLEX SYMPATHETIC DYSTROPHY) and type II; (CAUSALGIA). (From Pain 1995 Oct;63(1):127-33)
Khalil (1980). "Benign chondroblastoma. A case report and review of the literature". Le Journal medical libanais. the Lebanese ...
... of the plasticity of mesenchymal cells when set into different microenvironments and static approaches used in literature. ... "Chondroblastoma." Human Pathology 24.9 (1993): 944-949. Web. 6 Dec. 2015. Chondroblastoma- Medscape Chondroblastoma- James C. ... "Chondroblastoma of Bone." Human Pathology 20.10 (1989): 965-976. Web. 5 Dec. 2015. Damron, Timothy A. "Chondroblastoma." ... There is no indication of a racial predilection for chondroblastoma. The etiology of chondroblastoma is uncertain, as there is ...
An aneurysmal bone cyst can arise from a pre-existing chondroblastoma, a chondromyxoid fibroma, an osteoblastoma, a giant cell ... A case report and review of the literature". J Craniomaxillofac Surg. 40 (8): e243-8. doi:10.1016/j.jcms.2011.10.026. PMID ...
Khalil (1980). "Benign chondroblastoma. A case report and review of the literature". Le Journal medical libanais. the Lebanese ...
The official designation of a primary bone tumor as a chondroblastoma depends on the histologic finding of foci of chondroid ... Chondroblastoma is a rare benign bone tumor of chondroblast origin that almost always occurs in a primary or secondary site of ... Zhang K, Gao Y, Dai H, Zhang S, Li G, Yu B. Chondroblastoma of the talus: a case report and literature review. J Foot Ankle ... Chondroblastoma of the femoral diaphysis: report of a rare phenomenon and review of literature. Hum Pathol. 2007 May. 38(5):803 ...
Hameed MR, Blacksin M, Das K, Patterson F, Benevenia J, Aisner S. Cortical chondroblastoma: report of a case and literature ... Chondroblastoma. In: Human Pathology 1993;24(9):944-49. [ Links ]. 4. Fines BP, Stacy GS. Chondroblastoma imaging. In: Medscape ... Benign chondroblastoma. In: JBJS (Br) 1966;48-B:92-104. [ Links ]. 3. Turcotte RE, Kurt A, Sim FH, Unni KK, McLeod RA. ... Chondroblastoma. In: Journal of Orhtopaedic Surgery 2008; 16(1):84-87. [ Links ]. 14. Suneja R, Grimer RJ, Belthur M, Jeys L, ...
A chondroblastoma is a rare, usually benign, tumor of bone that accounts for approximately 1% of all bone tumors. In 1931, ... Metastatic chondroblastoma. Report of a fatal case with a review of the literature on atypical, aggressive, and malignant ... encoded search term (Chondroblastoma) and Chondroblastoma What to Read Next on Medscape. Related Conditions and Diseases. * ... Chondroblastoma Treatment & Management. Updated: Dec 03, 2018 * Author: Timothy A Damron, MD; Chief Editor: Omohodion (Odion) ...
... free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI ... Aggressive scapular chondroblastoma with secondary metastasis--a case report and review of literature. Eur J Med Res. 2006;11(3 ... Chondroblastoma of bone. J Bone Joint Surg [Am] 2000;82:1140-5. doi: 10.1302/0301-620X.82B8.10791. [PubMed] [Cross Ref] ... Pulmonary metastases from chondroblastoma of the tibia. Report of a case. J Bone Joint Surg [Br] 1973;55(4):848-53. [PubMed] ...
E. Kunze and E. Peitsch, "Histology and biology of metastatic chondroblastoma. Report of a case with a review of the literature ... A. J. Ramappa, F. Y. I. Lee, P. Tang, J. R. Carlson, M. C. Gebhardt, and H. J. Mankin, "Chondroblastoma of bone," The Journal ... S. H. Sohn, S. A. Koh, D. G. Kim et al., "A case of spine origin chondroblastoma metastasis to lung," Cancer Research and ... F. Sailhan, F. Chotel, and R. Parot, "Chondroblastoma of bone in a pediatric population," Journal of Bone and Joint Surgery- ...
Metastatic chondroblastoma. Report of a fatal case with a review of the literature on atypical, aggressive, and malignant ... Malignant chondroblastoma. Report of two cases and review of the literature. Arch Pathol. 1969;88:371-6. ... Chondroblastoma; p 247-64.. *Strong DP, Grimer RJ, Carter SR, Tillman RM, Abudu A. Chondroblastoma of the femoral head: ... Chondroblastoma is a rare tumor that represents 1% to 2% of all primary bone tumors. [1-7] Prior to being defined as a distinct ...
22064125 - Chondroblastoma of the talus: a case report and literature review.. 12522625 - Complex bilateral polysyndactyly ...
... of the plasticity of mesenchymal cells when set into different microenvironments and static approaches used in literature. ... "Chondroblastoma." Human Pathology 24.9 (1993): 944-949. Web. 6 Dec. 2015. Chondroblastoma- Medscape Chondroblastoma- James C. ... "Chondroblastoma of Bone." Human Pathology 20.10 (1989): 965-976. Web. 5 Dec. 2015. Damron, Timothy A. "Chondroblastoma." ... There is no indication of a racial predilection for chondroblastoma. The etiology of chondroblastoma is uncertain, as there is ...
Karkhur Y, Tiwari A, Verma T, Maini L. Unusual presentation of chondroblastoma mimicking Trevors disease. J Postgrad Med. 2017 ... Treatment of proximal humeral tumors is presented and described with a revision of the literature about this topic, in the ... De Giorgi S., Maruccia F., Belviso V., Moretti B. (2019) Proximal Humerus Neoplasia: Revision of the Literature. In: Gumina S ... Osteochondroma presenting as a calcified mass in the sellar region and review of the literature. J Neurol Surg A Cent Eur ...
Case report and literature review. Enrique Hanff Lara-Barrag n; Ernesto Zamudio-Carrera; scar Antonio Mart nez-Molina ... Chondroblastoma of the proximal humerus treated with intracompartmental curettage and lyophilized bone graft. ...
... free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI ... The literature contains little data regarding COX. 2 expression in OBs. Studies on COX. 2 expression in osteoid osteoma14,15,16 ... 2 in chondroblastic cells was also shown in chondroblastoma10 and chondrosarcoma.22,23 Although we do not know exactly the ... 2 expression in OB is a factor in inducing inflammatory reaction such as that in osteoid osteoma and chondroblastoma or has ...
We reported an additional case and reviewed the existing literature. A 20-year-old man with a 2-month history of right ankle ... Aggressive chondroblastoma of the distal tibia is rare, and below-knee amputation had been the standard surgical procedure. ... fibular graft and ankle arthrodesis may be an effective and economical alternative method for aggressive chondroblastoma in the ... Aggressive chondroblastoma of the distal tibia is further rare. For patients with aggressive chondroblastoma, treatments ...
Cheng, S., Gomes, L., da Cruz, M. (2009). Temporal Bone Chondroblastoma. Otology & Neurotology, 30(5), 688-9. [More Information ... scanning electron micrograph images and literature review. Journal of Laryngology and Otology, 121(10), 993-997. [More ... Cheng, S., Gomes, L., da Cruz, M. (2009). Temporal Bone Chondroblastoma. Otology & Neurotology, 30(5), 688-9. [More Information ... scanning electron micrograph images and literature review. Journal of Laryngology and Otology, 121(10), 993-997. [More ...
A rare case of vulvar langerhans cell histiocytosis and review of the literature/ Nadir bir vulvar langerhans hucreli ... The differential diagnosis includes an eurysmal bone cysts, chondroblastoma, chondromyxoid fibroma, giant cell reparative ... All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for ...
Immunohistochemistry differentiates the PVNS from chondroblastoma as PVNS is CD68 positive and chondroblastoma is S-100 ... The lesion arising in temporomandibular joint is exceedingly rare with only few cases having being reported in literature so ... The aggressive resection has been advocated in previous literature with long term radiological follow up with MRI. The ... The histopathology reports share the same features as that reported in the literature with CD 68 positivity on ...
Active forces are transmitted to the proximity of the literature. Absence of cartilage thickness. During the late stance phase ... Chapter tumors and related conditions enchondroma epiphysis chondroblastoma gct chondrosarcoma metaphysis osteosarcoma abc, ...
Lambert J, Verstraeten T, Mermuys K. Chondroblastoma: an unusual cause of shoulder pain in adolescence. J Belg Soc Radiol. 2016 ... Karami M, Soleimani M, Shiari R. Pigmented villonodular synovitis in pediatric population: review of literature and a case ... Bone lesions include osteoid osteoma, chondroblastoma, cortical desmoids, focal fibrocartilaginous dysplasia, and dysplasia ... a case report and literature review. J Pediatr Orthop B. 2017;26:41-7.CrossRefGoogle Scholar ...
Chondroblastoma-like mass of the temporal bone, secondary aneurysmal bone cyst, and intracerebral hemorrhage in a patient with ... The relationship between malignancy risk and CFCS is unclear with few cases published in the literature. The purpose of this ... This is the first case to document an association between CFCS and chondroblastoma. ... of a large intracerebral hemorrhage arising from a temporal bone mass with histopathology most consistent with chondroblastoma ...
Although a majority of them are benign, few can become malignant and even metastasize.… Chondroblastoma: Read more about ... Chondroblastoma also known as Codman tumor, calcifying giant cell tumor or epiphyseal chondromatous giant cell tumor is a rare ... Yang J, Tian W, Zhu X, Wang J. Chondroblastoma in the long bone diaphysis: a report of two cases with literature review. Chin J ... Chondroblastoma. Hum Pathol. 1993;24:944-949.. *Bloem JL, Mulder JD. Chondroblastoma: a clinical and radiological study of 104 ...
Chondroblastoma is uncommon, accounting for less than 1% of all primary bone tumors.. Chondroblastoma: An Update ... All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for ...
... as reviewed in the literature. The authors report the first case of chondroblastoma ethmoid-spheno-petro-clival associated with ... Chondroblastoma-like chondroma of soft tissue: report of the first case in the base of skull. Raparia K, Lin JW, Donovan D, ... Chondroblastoma of the apex portion of petrousal bone. Dran G, Niesar E, Vandenbos F, Noel G, Paquis P, Lonjon M. Childs Nerv ... Chondroblastoma of the skull base. Chrerkaev VA, Korshunov AG, Gasparian TG, Kadasheva AB, Semenova LA, Shishkina LV. Zh Vopr ...
Presentation of two clinical cases and revision of the literature. Med Oral Patol Oral Cir Bucal. 13:E61-E64. 2008.PubMed/NCBI ... Reid LB, Wong DS and Lyons B: Chondroblastoma of the temporal bone: A case series, review, and suggested management strategy. ... Tong Y: Role of duplex ultrasound in the diagnosis and assessment of carotid body tumour: A literature review. Intractable Rare ... Beyond that, however, a group of rare tumors, such as chondroblastoma, fibrohistiocytoma and inflammatory myofibroblastic ...
Literature. A-D E-O P-T U-Z before 1995 1995-1999. 2000-2004 2005-2009 2010- A B C D E F G H I J K L M N O P Q R S T U V W X Y ... Chondroblastoma: An Update.. Next Article:. Serum Bilirubin Concentrations in Patients With Takayasu Arteritis.. ...
RUNX1 deletion/amplification in therapy-related acute myeloid leukemia: A case report and review of the literature. RUNX1 ... chondroblastoma, CMF, metastasis, myeloma (any bone lesion detected in age above 40 years, must be ruled out for metastasis and ...
  • RFA for chondroblastoma has been described in several reports, but follow-up has been shorter than for surgical treatment, and caution is recommended for cases in which the lesions are larger than 2.5 cm and when there is no subchondral bone support. (medscape.com)
  • Although different surgical techniques have been developed to repair chondral and osteochondral lesions, the literature demonstrates only fair to good results when performed, even in the appropriate circumstances. (thefreedictionary.com)
  • GCTs involving the Clivus are extremely rare lesions and less than 15 cases are described in the literature. (biomedcentral.com)
  • In addition, systematic literature review allowed us to generate a histology-based diagnostic algorithm of the most common clival lesions. (biomedcentral.com)
  • The work of Aigner et al suggests that chondroblastoma should be reclassified as a bone-forming neoplasm versus a cartilaginous neoplasm due to the presence of osteoid matrix, type I collagen, and absence of true cartilage matrix (collagen II). (wikipedia.org)
  • Chondroblastoma is very uncommon, accounting for only 1-2% of all bone tumors. (wikipedia.org)
  • The etiology of chondroblastoma is uncertain, as there is no specific characteristic abnormality or chromosomal breaking point observed, despite cytogenetic abnormalities being highly specific for some tumors. (wikipedia.org)
  • We also review the literature starting from the earliest recognition of this entity and the various studies done to explain its molecular pathogenesis and prognostic importance.Results and ConclusionsRecognition of SWI/SNF complex-deficient dedifferentiated endometrial carcinoma is important as these tumors do not respond to platinum-based chemotherapy, and consideration of alternative therapies is often necessary. (journaltocs.ac.uk)
  • The majority of the tumors reported in the literature arise from the thyroid cartilage (thyroid cartilage: 80%, cricoid cartilage: 15%, epiglottis: 5%) and have predilection for male (M:F =10:1), with the mean age at the presentation of 40 years. (appliedradiology.com)
  • The majority of tumors of the patella are benign, with a significant incidence of giant cell tumors and chondroblastoma. (biomedcentral.com)
  • Once researchers understand more about these pathways, says Lewis, they can consider ways of blocking them with drugs, particularly in tumors such as MPC-rich sarcomas--which, unlike chondroblastoma, can be deadly. (medindia.net)
  • The following image depicts the epiphyseal location of a chondroblastoma of the femoral head. (medscape.com)
  • Both Indian Hedgehog/Parathyroid Hormone-related Protein (IHh/PtHrP) and fibroblast growth factor (FGF) signaling pathways, important for development of the epiphyseal growth plate, are active in chondroblastoma leading to greater proliferation among the cells in the proliferating/pre-hypertrophic zone (cellular-rich area) versus the hypertrophic/calcifying zone (matrix-rich area). (wikipedia.org)
  • AIM: to present our experience on spinal sclerosing epithelioid fibrosarcoma (SEF) and review the existing literature pertaining to SEF of the spine. (bvsalud.org)
  • These findings suggest that chondroblastoma is derived from a mesenchymal cell undergoing chondrogenesis via active growth-plate signaling pathways (see Endochondral ossification). (wikipedia.org)
  • The results of Romeo and colleagues favor the view of Edel et al of chondroblastoma being cartilaginous in nature but recognize that any definitive determinations regarding the origin of this neoplasm are not possible because of the plasticity of mesenchymal cells when set into different microenvironments and static approaches used in literature. (wikipedia.org)
  • Romeo et al have observed chondroblastoma neoplasms to be composed of mesenchymal cells that have completed normal chondrogenesis along with the production of osteoid and collagen I that could be the result of transdifferentiation of chondrocytes towards osteoblasts. (wikipedia.org)
  • There is a scanty literature support describing the incidence, mechanism of lateral dislocations of thoracolumbar spine and its management describing the reduction techniques. (jocr.co.in)
  • The clinical presentation of a chondroblastoma often includes insidious onset of pain, local tenderness, decreased range of motion, and swelling. (icjr.net)