An organochlorine insecticide that has been used as a pediculicide and a scabicide. It has been shown to cause cancer.
A cholinesterase inhibitor that is used as a systemic insecticide, an acaricide, and nematocide. (From Merck Index, 11th ed)
Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics.
An insecticide and herbicide that has also been used as a wood preservative. Pentachlorphenol is a widespread environmental pollutant. Both chronic and acute pentachlorophenol poisoning are medical concerns. The range of its biological actions is still being actively explored, but it is clearly a potent enzyme inhibitor and has been used as such as an experimental tool.
Parasitic attack or subsistence on the skin by members of the order Phthiraptera, especially on humans by Pediculus humanus of the family Pediculidae. The hair of the head, eyelashes, and pubis is a frequent site of infestation. (From Dorland, 28th ed; Stedman, 26th ed)
An organochlorine insecticide whose use has been cancelled or suspended in the United States. It has been used to control locusts, tropical disease vectors, in termite control by direct soil injection, and non-food seed and plant treatment. (From HSDB)
A contagious cutaneous inflammation caused by the bite of the mite SARCOPTES SCABIEI. It is characterized by pruritic papular eruptions and burrows and affects primarily the axillae, elbows, wrists, and genitalia, although it can spread to cover the entire body.
Lice of the genus Pediculus, family Pediculidae. Pediculus humanus corporus is the human body louse and Pediculus humanus capitis is the human head louse.
A highly poisonous substance that was formerly used as an insecticide. The manufacture and use has been discontinued in the U.S. (From Merck Index, 11th ed)
An order of basidiomycetous fungi; some species are parasitic on grasses (POACEAE) and maize.
Hair grooming, cleansing and modifying products meant for topical application to hair, usually human. They include sprays, bleaches, dyes, conditioners, rinses, shampoos, nutrient lotions, etc.
A polychlorinated compound used for controlling a variety of insects. It is practically water-insoluble, but readily adheres to clay particles and persists in soil and water for several years. Its mode of action involves repetitive nerve-discharges positively correlated to increase in temperature. This compound is extremely toxic to most fish. (From Comp Biochem Physiol (C) 1993 Jul;105(3):347-61)
A man-made compound previously used to control termites and other insects. Even though production of heptachlor was phased out of use in the United States during the late 1980's it remains in soil and hazardous waste sites. It is clearly toxic to animals and humans but, the International Agency for Research on Cancer (IARC) has determined that heptachlor is not classifiable as to its carcinogenicity to humans. (From ATSDR Public Heath Statement, April 1989)

Rhodanobacter lindaniclasticus gen. nov., sp. nov., a lindane-degrading bacterium. (1/210)

Lindane-degrading activity under aerobic conditions has been observed in two bacterial strains: UT26, phenotypically identified as Sphingomonas paucimobilis, and a new single unidentified isolate named RP5557T. The rrs (16S rDNA) sequences for both strains and the phenotypic characteristics for the unidentified isolate RP5557T were determined. RP5557T does not have high identity (less than 90% in all cases) with any sequence in the GenBank or RDP databases. A phylogenetic analysis based on rrs sequences indicated that RP5557T belongs to the gamma-Proteobacteria in a coherent phylum that includes the genera Xanthomonas and Xylella (100% bootstrap), whereas UT26 is clearly separate from the Xanthomonas cluster. Based on the phylogenetic analyses and on the phenotypic characteristics, a new genus, Rhodanobacter, containing a single species, Rhodanobacter lindaniclasticus, is proposed for strain RP5557T (= LMG 18385T), which becomes the type strain.  (+info)

Effect of tetrandrine on proto-oncogene c-fos expression in rat cerebrum. (2/210)

AIM: To detect the effect of tetrandrine (Tet) on c-fos gene expression in cerebrum induced by lindane, a neurotoxicant which activates Ca2+ channels. METHODS: Northern and dot blotting, dual wavelength thin layer chromatography scanner, were used in this study. RESULTS: Lindane 30 mg.kg-1 given by intragastric gavage (i.g.) increased the expression of c-fos gene to 146 mm2 in rat cerebrum 1 h after treatment. Tet 1, 2, and 4 mg.kg-1 given by i.g. 30 min prior to lindane reduced c-fos gene expression in a concentration-dependent manner. Expressed genes reached only 86, 40, and 39 mm2, respectively. CONCLUSION: Tet inhibited c-fos gene expression in rat cerebrum induced by Ca2+ agonist-lindane.  (+info)

Mechanisms of delta-hexachlorocyclohexane toxicity: I. Relationship between altered ventricular myocyte contractility and ryanodine receptor function. (3/210)

Several isomers of hexachlorocyclohexanes (HCHs) have been shown to be toxic to mammals. Previous studies have revealed that the delta isomer (delta-HCH) was particularly potent toward disrupting Ca2+ homeostasis in a variety of excitable and nonexcitable cells and altering contractility of cardiac muscle. The effects of the delta and gamma isomers of HCH were further investigated on isolated ventricular myocytes from guinea pig and on single cardiac ryanodine receptor (RyR2) Ca2+-release channels from cardiac SR vesicles. Intracellular Ca2+ transients were examined in electrically stimulated cells using the fluorescent dye indo-1, and twitch contractions of myocytes were analyzed using a video-based edge motion detection system. Exposure of myocytes to delta- but not gamma-HCH depressed the peak of intracellular Ca2+ transients and prolonged recovery time. These effects were correlated with the ability of delta-HCH to inhibit the binding of [3H]ryanodine, a conformationally sensitive probe for RyR2 function, to SR preparations (IC50 = 2 and 18 microM for high- and low-affinity interactions, respectively). Measurements of single-channel gating kinetics under voltage-clamp provided direct evidence of a potent isoform-selective activation of RyR2 by delta-HCH. Results from these studies revealed that delta-HCH alters Ca2+ homeostasis and contractility in cardiac myocytes and that the mechanism can be ascribed, at least in part, to a direct interaction with the RyR2 channel complex.  (+info)

Mechanisms of delta-hexachlorocyclohexane toxicity: II. Evidence for Ca2+-dependent K+-selective ionophore activity. (4/210)

delta-Hexachlorocyclohexane (delta-HCH) interacts with cardiac ryanodine-sensitive Ca2+ channels (RyR2), accounting in part for altered Ca2+ transients and contractility (reported in companion report). Analysis of channel gating kinetics in the presence of delta-HCH also revealed a nonfluctuating membrane current that remained even after RyR2 channels were blocked. We further elucidated the nature of a direct interaction between delta-HCH and biological membranes by measuring ionic currents across planar lipid bilayers made from defined lipids lacking cellular protein using voltage-clamp. Dimethyl sulfoxide, in the presence or absence of 50 microM gamma-HCH (lindane) or delta-HCH, produced negligible steady-state current with symmetric 100 mM CsCl in the range of +/-50 mV. However, the addition of 50 microM Ca2+ to the bilayer chamber in the presence of delta-HCH induced a profound increase in ionic permeability that was not seen in the presence of gamma-HCH or dimethyl sulfoxide control. Significantly, the permeability increase 1) was proportional with increasing Ca2+ to approximately 600 microM and saturated between 1 and 2 mM Ca2+ regardless of holding potential, 2) occurred only when delta-HCH and Ca2+ were added to the same side of the membrane, and 3) was independent of the order of addition or of the side of the membrane to which delta-HCH and Ca2+ was added. The Ca2+-dependent current produced by delta-HCH was highly selective for monovalent cations (K+ >> Cs+ > Na+), with negligible conductance for Ca2+ or Cl-. In symmetric 100 mM K+, the conductance induced with 50 microM concentration each of delta-HCH and Ca2+ was 4.25 pA/mV. The results show that delta-HCH increases the ionic permeability of phospholipid membranes by two distinct Ca2+-dependent mechanisms: one mediated through RyR and the other mediated by a unique ionophore activity.  (+info)

A single amino acid confers barbiturate sensitivity upon the GABA rho 1 receptor. (5/210)

Many structurally diverse general anaesthetics enhance inhibitory neurotransmission in the central nervous system by interacting with the GABAA receptor. By contrast, GABA receptors composed of the rho 1 subunit are anaesthetic-insensitive. Here, we demonstrate that both delta-hexachlorocyclohexane (delta-HCH; 1-100 microM), a positive allosteric modulator of the GABAA receptor, and the anaesthetic pentobarbitone (10-600 microM) have no effect on GABA-evoked currents mediated by wild-type rho 1 recombinant receptors (expressed in Xenopus laevis oocytes). By contrast, these agents produce up to a 10 fold enhancement of GABA responses transduced by a rho 1 receptor in which a transmembrane located isoleucine residue is replaced by serine. However, not all general anaesthetics were similarly influenced by this mutation, because propofol and 5 beta-pregnan-3 alpha-ol-20-one (5 beta 3 alpha) remained ineffective. These data are discussed in relation to the specificity of general anaesthetic action.  (+info)

Effect of lindane and phenobarbital on cyclooxygenase-2 expression and prostanoid synthesis by Kupffer cells. (6/210)

Prostaglandins (PGs) have been implicated in tumor promotion. In this study, we investigated the effect of the hepatic tumor promoters lindane and phenobarbital (PB) on the PG metabolism of Kupffer cells in vitro and in vivo, in particular on the expression of cyclooxygenase (COX), the leading enzyme in prostanoid synthesis. Exposure of primary cultures of Kupffer cells to lindane for 1 h stimulated the production of the PGs PGE(2) and PGD(2) markedly (up to 50-fold) and that of PGF(2alpha) by >3-fold. This effect was accompanied by an increase in the COX-2 protein, as demonstrated by western blotting. Similarly, PB, which shares several effects with lindane in rat liver, also clearly induced COX-2. Lindane and PB affected the PG synthesis in vitro and in vivo in Kupffer cells of rats that had been treated with the two compounds for 56 days. Kupffer cells, which were isolated at days 2, 5 and 56 of the treatment, showed a significant increase in the levels of COX-2 mRNA and protein. Total COX activity was increased approximately 2-fold and 3- to 5-fold in Kupffer cell homogenates of PB- and lindane-treated animals, respectively, compared with the untreated controls. These results suggest that paracrine mechanisms may contribute to the tumor-promoting activity of lindane and PB, stimulating the production of PGs by Kupffer cells.  (+info)

Reproductive and endocrine function in rams exposed to the organochlorine pesticides lindane and pentachlorophenol from conception. (7/210)

There is controversy over the potential endocrine modulating influence of pesticides, particularly during sensitive phases of development. In this study, ram lambs were exposed to lindane and pentachlorophenol from conception to necropsy at 28 weeks of age. The rams (and their mothers) were given untreated feed (n = 7) or feed treated with 1 mg kg-1 body weight per day of lindane (n = 12) or pentachlorophenol (n = 5). Semen was collected from 19 weeks onwards and reproductive behaviour was tested at 26 weeks. Serum was collected every 2 weeks and at 27 weeks every 15 min for 6 h during both day and night, and for 1 h before and 5 h after stimulation with GnRH, adrenocorticotrophic hormone and thyroid-stimulating hormone. The pesticides did not affect body weight and ejaculate characteristics, or cause overt toxicity. In pentachlorophenol-treated rams, scrotal circumference was increased. However, seminiferous tubule atrophy was more severe and epididymal sperm density was reduced in comparison with untreated rams at necropsy (P < 0.05). Thyroxine concentrations were lower in pentachlorophenol-treated rams than in untreated rams (P < 0.05). However, after thyroid-stimulating hormone treatment, the thyroxine response was unaltered. Reproductive behaviour was reduced in lindane-treated rams compared with control rams (P < 0.05). Serum LH and oestradiol concentrations during reproductive development, LH pulse frequency at 27 weeks and testosterone secretion after GnRH treatment were lower in lindane-treated rams than in untreated rams (P < 0.05). In summary, the effects of pentachlorophenol on the testis may be linked to a decrease in thyroxine concentrations, and reduced reproductive behaviour in lindane-treated rams may be related to decreased LH, oestradiol and testosterone concentrations.  (+info)

Two different types of dehalogenases, LinA and LinB, involved in gamma-hexachlorocyclohexane degradation in Sphingomonas paucimobilis UT26 are localized in the periplasmic space without molecular processing. (8/210)

gamma-Hexachlorocyclohexane (gamma-HCH) is one of several highly chlorinated insecticides that cause serious environmental problems. The cellular proteins of a gamma-HCH-degrading bacterium, Sphingomonas paucimobilis UT26, were fractionated into periplasmic, cytosolic, and membrane fractions after osmotic shock. Most of two different types of dehalogenase, LinA (gamma-hexachlorocyclohexane dehydrochlorinase) and LinB (1,3,4,6-tetrachloro-1,4-cyclohexadiene halidohydrolase), that are involved in the early steps of gamma-HCH degradation in UT26 was detected in the periplasmic fraction and had not undertaken molecular processing. Furthermore, immunoelectron microscopy clearly showed that LinA and LinB are periplasmic proteins. LinA and LinB both lack a typical signal sequence for export, so they may be secreted into the periplasmic space via a hitherto unknown mechanism.  (+info)

Lindane is defined in medical terms as an agricultural and pharmaceutical compound that contains thegamma-isomer of hexachlorocyclohexane (γ-HCH). It has been used as a topical treatment for scabies and lice infestations, although its use is now limited due to concerns about toxicity and environmental persistence. Lindane works by disrupting the nervous system of insects, leading to paralysis and death. However, it can also have similar effects on mammals, including humans, at high doses or with prolonged exposure. Therefore, its use is restricted and alternatives are recommended for the treatment of scabies and lice.

Carbofuran is a highly toxic systemic pesticide that belongs to the carbamate family. It is used primarily to control insects in soil before planting and on crops after emergence. Carbofuran works by inhibiting the enzyme cholinesterase, which leads to an accumulation of acetylcholine and results in overstimulation of the nervous system in insects, ultimately causing their death.

In humans, exposure to carbofuran can cause symptoms such as nausea, vomiting, diarrhea, abdominal cramps, headache, dizziness, visual disturbances, and muscle twitching. In severe cases, it can lead to respiratory failure, convulsions, and even death. Carbofuran is classified as a Category I toxic pesticide by the Environmental Protection Agency (EPA) in the United States, indicating that it is highly hazardous.

Due to its high toxicity and potential for environmental harm, carbofuran has been banned or restricted in many countries around the world. In the United States, the use of carbofuran on food crops was phased out in 2009, and its registration for most uses was canceled in 2010. However, it is still used in some parts of the world for non-food crop applications.

Insecticides are substances or mixtures of substances intended for preventing, destroying, or mitigating any pest, including insects, arachnids, or other related pests. They can be chemical or biological agents that disrupt the growth, development, or behavior of these organisms, leading to their death or incapacitation. Insecticides are widely used in agriculture, public health, and residential settings for pest control. However, they must be used with caution due to potential risks to non-target organisms and the environment.

Pentachlorophenol is not primarily a medical term, but rather a chemical compound with some uses and applications in the medical field. Medically, it's important to understand what pentachlorophenol is due to its potential health implications.

Pentachlorophenol (PCP) is an organochlorine compound that has been widely used as a pesticide, wood preservative, and disinfectant. Its chemical formula is C6HCl5O. It is a white crystalline solid with a distinct, somewhat unpleasant odor. In the environment, pentachlorophenol can be found in soil, water, and air as well as in various organisms, including humans.

Pentachlorophenol has been associated with several potential health risks. It is classified as a probable human carcinogen by the International Agency for Research on Cancer (IARC) and as a possible human carcinogen by the United States Environmental Protection Agency (EPA). Exposure to pentachlorophenol can occur through inhalation, skin contact, or ingestion. Potential health effects include irritation of the skin, eyes, and respiratory tract; damage to the liver and kidneys; neurological issues; and reproductive problems.

In a medical context, pentachlorophenol might be relevant in cases where individuals have been exposed to this compound through occupational or environmental sources. Medical professionals may need to assess potential health risks, diagnose related health issues, and provide appropriate treatment.

A lice infestation, also known as pediculosis, is a condition characterized by the presence and multiplication of parasitic insects called lice on a person's body. The three main types of lice that can infest humans are:

1. Head lice (Pediculus humanus capitis): These lice primarily live on the scalp, neck, and behind the ears, feeding on human blood. They lay their eggs (nits) on hair shafts close to the scalp. Head lice infestations are most common in children aged 3-12 years old.

2. Body lice (Pediculus humanus corporis): These lice typically live and lay eggs on clothing, particularly seams and collars, near the body's warmest areas. They move to the skin to feed on blood, usually at night. Body lice infestations are more common in people who experience homelessness or overcrowded living conditions with limited access to clean clothing and hygiene facilities.

3. Pubic lice (Pthirus pubis): Also known as crab lice, these lice primarily live in coarse body hair, such as the pubic area, armpits, eyelashes, eyebrows, beard, or mustache. They feed on human blood and lay eggs on hair shafts close to the skin. Pubic lice infestations are typically sexually transmitted but can also occur through close personal contact with an infected individual or sharing contaminated items like bedding or clothing.

Symptoms of a lice infestation may include intense itching, tickling sensations, and visible red bumps or sores on the skin caused by lice bites. In some cases, secondary bacterial infections can occur due to scratching. Diagnosis is usually made through visual identification of lice or nits on the body or clothing. Treatment typically involves topical medications, such as shampoos, creams, or lotions, and thorough cleaning of bedding, clothing, and personal items to prevent reinfestation.

Dieldrin is a chlorinated hydrocarbon insecticide that was widely used in the past for agricultural and household pest control. It is a white, odorless, crystalline solid that is insoluble in water but soluble in organic solvents. Dieldrin has high toxicity to both insects and mammals, including humans. It can cause a range of harmful health effects, such as seizures, damage to the nervous system, and liver and kidney damage. Dieldrin was banned for most uses in the United States in 1974 due to its persistence in the environment and potential to accumulate in the food chain. It is now classified as a persistent organic pollutant (POP) and is regulated under international treaties.

Scabies is a contagious skin condition caused by the infestation of the human itch mite (Sarcoptes scabiei var. hominis). The female mite burrows into the upper layer of the skin, where it lays its eggs and causes an intensely pruritic (itchy) rash. The rash is often accompanied by small red bumps and blisters, typically found in areas such as the hands, wrists, elbows, armpits, waistline, genitals, and buttocks. Scabies is transmitted through direct skin-to-skin contact with an infected individual or through sharing of contaminated items like bedding or clothing. It can affect people of all ages, races, and socioeconomic backgrounds, but it is particularly common in crowded living conditions, nursing homes, and child care facilities. Treatment usually involves topical medications or oral drugs that kill the mites and their eggs, as well as thorough cleaning and laundering of bedding, clothing, and towels to prevent reinfestation.

"Pediculus" is the medical term for a type of small, wingless parasitic insect that can be found in human hair and on the body. There are two main species that affect humans:

1. Pediculus humanus capitis - also known as the head louse, it primarily lives on the scalp and is responsible for causing head lice infestations.
2. Pediculus humanus corporis - also known as the body louse, it typically lives in clothing and on the body, particularly in seams and folds of clothing, and can cause body lice infestations.

Both species of Pediculus feed on human blood and can cause itching and skin irritation. They are primarily spread through close personal contact and sharing of items such as hats, combs, and clothing.

Aldrin is a chemical compound with the formula C12H15ClN2. It is an organochlorine insecticide that was widely used in the past for agricultural and household pest control. Aldrin is a gray, crystalline solid that is almost insoluble in water but soluble in organic solvents.

Aldrin is a persistent organic pollutant (POP) that can accumulate in the fatty tissues of living organisms and pose a risk to human health and the environment. It has been banned or restricted in many countries due to its toxicity and environmental persistence.

In humans, exposure to aldrin can cause a range of health effects, including headaches, dizziness, nausea, vomiting, muscle weakness, tremors, and convulsions. Long-term exposure has been linked to damage to the nervous system, liver, and kidneys, as well as an increased risk of cancer.

It's important to note that Aldrin is not a medical term, but a chemical one. Therefore, it doesn't have a medical definition in terms of a condition or disease, but rather as a chemical compound with certain properties and uses, as well as potential health risks.

Ustilaginales is a taxonomic order of fungi that are primarily known as smut fungi. These fungi are characterized by their ability to infect and colonize the plant tissues of various monocotyledonous plants, including grasses, cereals, and sedges. The infection process often results in the formation of dark spores, which give the infected plant parts a sooty or dusty appearance.

The Ustilaginales order contains several families, genera, and species, many of which are economically important as crop pathogens. For example, some smut fungi can cause significant yield losses in crops such as corn, wheat, barley, and sorghum. The spores produced by these fungi can also have negative impacts on human health, causing allergic reactions or respiratory issues when inhaled.

It's worth noting that some species of Ustilaginales are being investigated for their potential industrial applications, such as the production of biofuels and other valuable chemicals.

Hair preparations refer to cosmetic or grooming products that are specifically formulated to be applied to the hair or scalp for various purposes such as cleansing, conditioning, styling, coloring, or promoting hair growth. These preparations can come in different forms, including shampoos, conditioners, hair masks, serums, gels, mousses, sprays, and dyes. They may contain a wide range of ingredients, such as detergents, moisturizers, proteins, vitamins, minerals, and other nutrients that can help improve the health, appearance, and manageability of the hair. Some hair preparations may also contain medications or natural extracts that have therapeutic properties for treating specific hair or scalp conditions, such as dandruff, dryness, oiliness, thinning, or hair loss.

Endosulfan is a synthetic, broad-spectrum insecticide that was widely used in agriculture for controlling a variety of pests. It belongs to the class of organic compounds known as organochlorines, which are characterized by having a chlorinated aromatic ring. Endosulfan exists in two stereoisomeric forms, alpha-endosulfan and beta-endosulfan, and is often used as a mixture of these two forms.

Endosulfan has been linked to several health problems, including neurological disorders, endocrine disruption, and reproductive toxicity. It is also considered to be highly toxic to aquatic life and birds. Due to its persistence in the environment and potential for bioaccumulation, endosulfan has been banned or restricted in many countries around the world.

The medical definition of Endosulfan can be described as a synthetic organochlorine insecticide that is highly toxic and has been linked to various health problems, including neurological disorders, endocrine disruption, and reproductive toxicity. It is no longer approved for use in many countries due to its environmental persistence and potential health risks.

Heptachlor is a synthetic, chlorinated hydrocarbon insecticide that was widely used in the past for agricultural and residential pest control. It is a colorless to white crystalline solid with a mild chemical odor. Heptachlor is highly toxic to both insects and mammals, including humans. It can cause damage to the liver and nervous system, and long-term exposure has been linked to cancer in animals.

Heptachlor was banned for most uses in the United States in 1978 due to its persistence in the environment and potential health risks. However, it can still be found in some older pesticide formulations and in contaminated soil, water, and air. Heptachlor is highly persistent in the environment and can accumulate in the food chain, posing a risk to wildlife and human health.

In humans, lindane affects the nervous system, liver, and kidneys, and may well be a carcinogen. Whether lindane is an ... With regard to lindane medications, the EPA conducted "down-the-drain" estimates of the amount of lindane reaching public water ... "Lindane Post Marketing Safety Review" (PDF). U.S. FDA. 2003. "Lindane Information". www.fda.gov. Archived from the original on ... Lindane is the gamma isomer of hexachlorocyclohexane ("γ-HCH"). In addition to the issue of lindane pollution, some concerns ...
Production of lindane unintentionally produces two other POPs α-HCH and β-HCH.[citation needed] Pentachlorobenzene (PeCB), is a ... Lindane (γ-hexachlorocyclohexane), a pesticide used as a broad spectrum insecticide for seed, soil, leaf, tree and wood ... are insecticides as well as by-products in the production of lindane. Large stockpiles of HCH isomers exist in the environment ... treatment, and against ectoparasites in animals and humans (head lice and scabies). Lindane rapidly bioconcentrates. It is ...
Lindane is still used in a shampoo form in some non-European countries. Its licence was withdrawn by the European Medicines ... Lindane is not recommended in pregnant and breastfeeding women, children under the age of two years, and people who have ... ISBN 978-0-323-07909-9. "Lindane Shampoo, USP, 1%". FDA. 2002 Sangaré, Abdoul Karim; Doumbo, Ogobara K.; Raoult, Didier (2016 ...
Lindane is one of the primary pesticides used on cocoa farms. The Environmental Protection Agency has released a study on ... "Lindane (Gamma-Hexachlorocyclohexane)" (PDF). Environmental Protection Agency. Retrieved 28 April 2017. "Fair For Life ... lindane stating the acute effects caused by inhalation cause irritation to the respiratory track as well as seizures and ...
"Dumped lindane costs dear". Pesticides News. 30: 5. 1995. Archived from the original on 24 October 2007. Retrieved 22 November ... In 1995 a major pollution incident occurred when lindane and mercury seed dressing were poured down a drain which leads into ...
nov., a lindane-degrading bacterium". International Journal of Systematic Bacteriology. 49 Pt 1: 19-23. doi:10.1099/00207713-49 ... from soil from a ginseng field from Poecheon in Korea.Rhodanobacter lindaniclasticus has the ability to degrade lindane. Parte ...
Lindane was approved in 1981 for the treatment of head lice. There were significant health risks associated with the drug; ... "Lindane Shampoo, USP, 1%" (PDF). FDA. "Drugs@FDA: FDA Approved Drug Products: New Drug Application (NDA): 019918". FDA. "CENTER ...
"IARC Monographs evaluate DDT, lindane, and 2,4-D" (PDF). Archived (PDF) from the original on April 13, 2020. Retrieved August ... it was replaced by lindane. DDT became a prime target of the growing anti-chemical and anti-pesticide movements, and in 1967 a ...
Heptachlor Lindane, BHC Banned in California. Banned for agricultural use in the US by the EPA in 2006. Based on a risks to bee ... "Addendum to the 2002 Lindane Reregistration Eligibility Decision (RED)" (PDF). US Environmental Protection Agency. 2006. ...
Teunis van der Linden, Dutch chemist - Lindane. Jules Antoine Lissajous, French physicist - Lissajous curve, Lissajous orbit. ...
DDT, BHC (Lindane) or Parathion are effective measures. A review of Biston Leach, 1815 (Lepidoptera, Geometridae, Ennominae) ...
"IARC Monographs evaluate DDT, lindane, and 2,4-D" (PDF). 23 June 2015. Retrieved 14 February 2016. Loomis, Dana; Guyton, ... Loomis, Dana (June 22, 2015). "Carcinogenicity of lindane, DDT, and 2,4-dichlorophenoxyacetic acid". The Lancet Oncology. 16 (8 ... "Carcinogenicity of lindane, DDT, and 2,4-dichlorophenoxyacetic acid". The Lancet Oncology. 16 (8): 891-892. doi:10.1016/S1470- ...
Other treatments include lindane, benzyl benzoate, crotamiton, malathion, and sulfur preparations. Lindane is effective, but ... "FDA Public Health Advisory: Safety of Topical Lindane Products for the Treatment of Scabies and Lice". Fda.gov. 30 April 2009. ... and lindane creams. Sexual contacts within the last month and people who live in the same house should also be treated at the ... "Outcomes of the California ban on pharmaceutical lindane: clinical and ecologic impacts". Environmental Health Perspectives. ...
nov., isolated from the drainage system of a lindane-producing factory". International Journal of Systematic and Evolutionary ... and non-motile bacterium from the genus Tessaracoccus which has been isolated from a drainage system from a lindane-producing ...
"Coaster", (Infested (The Lindane Conspiracy Part I) Fat Wreck Chords, 2018. 2001: Live C-Squat 3/31/01 2002: Straight Outta' ...
It is the "silent, cheap, easy to obtain and use, and effective." The common poison used is Lindane and it most commonly used ...
β-HCH, a lindane isomer and possible human carcinogen, was subsequently found in milk from several neighboring farms. A study ... of technical-grade lindane, though it has not been produced or used in the United States since 1985. As of 2009, the Stockholm ... It is a byproduct of the production of the insecticide lindane (γ-HCH). It is typically constitutes 5-14% ...
Permethrin, sulfur, lindane, dicophane, benzyl benzoate, ivermectin and crotamiton are well known ectoparasiticides. Broad- ...
The works required the removal of tons of soil poisoned with lindane residues. In May 1999, the new tower control was put into ...
The number of insects resistant to cyclodienes and lindane approached 300 by 1989. Later, in 1957, another use of the compound ...
... and lindane. Ligands which contribute to receptor activation typically have anxiolytic, anticonvulsant, amnesic, sedative, ...
1999). In areas where DDT resistance is encountered, malathion, propoxur or lindane is used. A traditional approach to ...
... lindane and aldrin, as well as VOCs and pesticide compounds. Lindane and aldrin were also detected by the NJDEP downstream of ...
... or lindane. Pet rats are a natural host for mites, but other small mammals kept as pets (mice, hamsters, rabbits, guinea pigs, ...
One such pollutant, lindane, has shown to accumulate in the adipose tissue of different organisms and is very toxic to aquatic ... Arthrobacter alkaliphilus is a subtype of Athrobacter that can degrade lindane and use it as a carbon source. It utilizes acid ... Arthrobacter Alkaliphilus' ability to degrade lindane can then have a major impact on its ecosystem. LPSN lpsn.dsmz.de UniProt ...
Resistance of head lice to insecticides such as lindane, malathion, phenothrin and permethrin has been reported. A 2021 ... Agents approved by the FDA for treatment of pediculosis include abametapir, topical ivermectin lotion, lindane, malathion, ... Insecticides used for the treatment of head lice include lindane, malathion, carbaryl, pyrethrum, piperonyl butoxide, ...
In chemical control, BHC, DDT, fenthion, fenitrothion, quinalphos, phosphamidon sprays and granules of lindane are used. Eggs ...
There are traces of heavy metals like copper and pesticides like endosulphan and lindane in it. Public Works Department sources ...
About 90% of the pesticide usage in India is accounted for by DDT and Lindane (BHC/HCH). There has been a shift to organic ...
... and it is typically still contained in commercial grade lindane used as insecticide. Lindane, however, has not been produced or ... It is a byproduct of the production of the insecticide lindane (γ-HCH) ...
In humans, lindane affects the nervous system, liver, and kidneys, and may well be a carcinogen. Whether lindane is an ... With regard to lindane medications, the EPA conducted "down-the-drain" estimates of the amount of lindane reaching public water ... "Lindane Post Marketing Safety Review" (PDF). U.S. FDA. 2003. "Lindane Information". www.fda.gov. Archived from the original on ... Lindane is the gamma isomer of hexachlorocyclohexane ("γ-HCH"). In addition to the issue of lindane pollution, some concerns ...
Lindane/Information submitted/CropLife International on behalf of Chemtura: - 27.01.06 - Introductory information and Lindane ... You are here: Stockholm Convention > The Convention > POPs Review Committee > Meetings > POPRC.1 > LINDANE Information ...
Environment Minister, Khaled Fahmy, announced that Egypt has had disposed of 241 tons of high-risk waste by transferring it to ...
Lindane kills parasites and their eggs. It is used to treat scabies (a skin infestation) and lice infestations of the head and ... Lindane does not prevent these infestations. When it is to be taken: Usually, one application of Lindane completely eliminates ... 3. Use Lindane only as directed by your doctor. Do not use more of it and do not use it more often than your doctor has ... How it should be taken: Lindane comes in thef orm of lotion, cream, and shampoo. Do not swallow it. Follow the instructions on ...
In many countries, lindane is also available for home use for control of fleas, ticks, ants and other insects. While lindane ... Based on the federal benchmark of allowable lindane contamination (19 parts per trillion), a single use of lindane shampoo ... Partial Lindane Bans in California and Europe October 24, 2000. In early September, Californias Governor Gray Davis signed a ... Lindane is also a suspected carcinogen with possible links to breast cancer incidence, and has been found in breast milk and ...
Toxic pathology of the hepatocyte in histiotypic culture part 2 activity of an organic chlorine compound lindane effect of a ... Reddy, M.S.; Rao, K.V. 1991: Toxic impact of lindane on aspartate and lindane aminotransferase activity levels of midgut gland ... Arisoy, M.; Kolankaya, N. 1997: Biodegradation of Lindane by Pleurotus sajor-caju and toxic effects of Lindane and its ... II--Effects of an organic chlorine compound: lindane. Effect of a foreign metabolizable substance and toxic effect Annales d& ...
... Synonym(s). .gamma.-1,2,3,4,5,6-Hexachlorocyclohexane , .gamma.-666 , .gamma.-BHC , .gamma.-Benzene hexachloride , . ... Lindane) , Omnitox , Ovadziak , Owadziak , PLK , Pedraczak , Pflanzol , Quellada , Sang-gamma , Spritz-Rapidin , Spritzlindane ... Lindane , 1,2,3,4,5,6-Hexachlorocyclohexane , 1,2,3,4,5,6-Hexachlorocyclohexane (gamma isomer) , 666 , Aalindan , Aficide , ...
Lindane treatment was separated from control animals in a dose dependent way, and was associated with an increase in the ... Lindane treatment was separated from control animals in a dose dependent way, and was associated with an increase in the ... Lindane treatment was separated from control animals in a dose dependent way, and was associated with an increase in the ... Lindane treatment was separated from control animals in a dose dependent way, and was associated with an increase in the ...
EPA bans lindane. The Environmental Protection Agency of the us has decided not to renew the registration of lindane, a highly ... Dissipation of lindane and fenvalerate on chickpea (Cicer arietinum L.). Dissipation of lindane (400 and 800 g ai ha-1) and ... Lindane. * More than 60 pesticides banned in other countries in use in India. ,p, Kerala banned the use of 15 pesticides in May ... Initial deposits of lindane on green pods were 2.85 and 5.36 mg kg-1 at recommended and double dose, which dissipated with half ...
Lindane. 58-89-9. 1988. Lithium hydride. 7580-67-8. 1988. L.P.G.. 68476-85-7. 1988. ...
IARC evaluates the carcinogenicity of lindane, DDT, and 2,4-D. IARC evaluates the carcinogenicity of lindane, DDT, and 2,4-D. ... Lindane was classified as carcinogenic to humans (Group 1) based on sufficient evidence in humans that lindane causes non- ... Use of lindane is banned or restricted in most countries. It is no longer used in Canada for agricultural purposes. ... IARC Press Release Number 236: IARC Monographs evaluate DDT, lindane, and 2,4-D ...
Residues of lindane may be persistent in soil and foods. There may also be direct human exposure to lindane through its use in ... A bioassay for possible carcinogenicity of lindane was conducted by administering the test chemical in the diet to Osborne- ... Lindane is an organochlorine pesticide that is registered for use in soil, foliar, and seed treatment for a large variety of ... Residues of lindane may be persistent in soil and foods. There may also be direct human exposure to lindane through its use in ...
Lindane; Endosulfan, Perfluorooctane sulfonic acid, its salts and perfluorooactane sulfonyl fluoride  UNEP/MAP (UNEP/MAP, 10/ ...
Production of lindane unintentionally produces two other POPs α-HCH and β-HCH.[citation needed] ... Lindane (γ-hexachlorocyclohexane), a pesticide used as a broad spectrum insecticide for seed, soil, leaf, tree and wood ... are insecticides as well as by-products in the production of lindane. Large stockpiles of HCH isomers exist in the environment ... treatment, and against ectoparasites in animals and humans (head lice and scabies). Lindane rapidly bioconcentrates. It is ...
A pick up service is provided by the Department of Environmental Health & Safety. Waste material should be placed into glass, metal, or plastic containers and kept closed. Segregate waste by hazard classes. Collect halogenated waste separate from nonhalogenated waste.. ...
6] Lindane is known to be absorbed after topical application, but oral ingestions are not rare. [7] Young age, malnourishment, ... Lindane is still used as a second-line topical prescription treatment for head lice and scabies. Adults are most likely to have ... Unintentional topical lindane ingestions--United States, 1998-2003. MMWR Morb Mortal Wkly Rep. 2005 Jun 3. 54(21):533-5. [QxMD ... Cholestyramine as an adsorbent in acute lindane poisoning: a murine model. Ann Emerg Med. 1993 Sep. 22(9):1392-7. [QxMD MEDLINE ...
Lindane. 0.40. 19. L19. 7439-97-6. Mercury. 0.10. 20. L20. 72-43-5. *. ...
FDA Issues Health Advisory Regarding Labeling Changes for Lindane Products. Labeling for Lindane products has been changed to ... This is an important warning .. since many sources (such as this tip in American Family Physician) list Lindane as one of ... The warning emphasizes that Lindane products have been, and continue to be, indicated as a second-line therapy for the ... While FDA believes that the benefits of Lindane outweigh the risks when used as directed, given the potential for neurotoxicity ...
The new boxed warning also states that Lindane Lotion and Lindane Shampoo are to be used with caution in patients who weigh ... has issued a Public Health Advisory concerning the use of topical formulations of Lindane Lotion and Lindane Shampoo for the ... physicians should consider this new safety information when deciding whether to prescribe Lindane Lotion or Lindane Shampoo for ... Because Lindane is absorbed through the skin, and because younger children have more skin surface area per pound of body weight ...
... lindane; mirex; pentachlorophenol (PCP); silvex; sodium arsenite; 2, 4, 5-T and toxaphene. ...
Association between environmental exposure to p, p′-DDE and lindane and semen quality Article 06 May 2014 ...
oh yes lindane the stuff for the occasion, the shit can give you cancer with too many applications ...
Lindan Lotion 100 ML (Lindane/Gamma Benzene Hexachloride). Shop Lindan Lotion 100 ML (Lindane/Gamma Benzene Hexachloride) ... Be the first to review "Lindan Lotion 100 ML (Lindane/Gamma Benzene Hexachloride)" Cancel reply. You must be logged in to post ... Lindan Lotion 100 ML (Lindane/Gamma Benzene Hexachloride). Thumbnail. Pack Size. Per Pill. Price. Quantity. Order. ... Lindan Lotion 100 ML (Lindane/Gamma Benzene Hexachloride). Permethrin Cream (Permethrin)Scabper Cream 30g (Permethrin) ...
Effect of Lindane to enzyme activity in the tissues of Liver, Muscle and Brain of freshwater fish, Cyprinus carpio. Vasanthi. J ... Hence, a need was felt to investigate a effect of sublethal exposure of Organ chlorine pesticide Lindane to enzyme content of ... It was found that GOT, GPT and LDH increased to the maximum level (after Lindane exposure) when compared to the controls (100 ...
  • and overstate the efficacy of Lindane Shampoo. (wikipedia.org)
  • Lindane comes in thef orm of lotion, cream, and shampoo. (stason.org)
  • 1. If you use an oil-based hair dressing, shampoo your hair with your regular shampoo and dry it thoroughly before applying lindane. (stason.org)
  • If you have head lice, wash comb and brushes with lindane shampoo and rinse them thoroughly with water to remove the drug. (stason.org)
  • Based on the federal benchmark of allowable lindane contamination (19 parts per trillion), a single use of lindane shampoo contaminates six million gallons of water, and the total lindane rinsed into California's water system each year contaminates five trillion gallons. (panna.org)
  • The U.S. Food and Drug Administration (FDA) has issued a Public Health Advisory concerning the use of topical formulations of Lindane Lotion and Lindane Shampoo for the treatment of scabies and lice. (aafp.org)
  • Lindane shampoo is a prescription medication that can kill lice and lice eggs. (cdc.gov)
  • For example, many shampoo products and other medical treatments for mites and lice still contain lindane, which has been used in health care for more than 50 years and is approved by the Food and Drug Administration, the Centers for Disease Control and Prevention and the Environmental Protection Agency. (wnd.com)
  • Lindane shampoo and lindane lotion. (epnet.com)
  • Medication guide lindane shampoo. (epnet.com)
  • Recommended Regimens - Lindane 1% shampoo applied for 4 minutes and then thoroughly washed off (not recommended for pregnant or lactating women or for children less than 2 years of age) or Permethrin 1% creme rinse applied to affected areas and washed off after 10 minutes or Pyrethrins with piperonyl butoxide applied to the affected area and washed off after 10 minutes. (cdc.gov)
  • Lindane is one of the few notorious DDT-style chlorinated pesticides to remain in widespread use in both industrialized and developing countries. (panna.org)
  • Groups around the world involved in the International POPs Elimination Network are working hard to ensure that the treaty is designed to allow the timely addition of pesticides such as lindane to the list of chemicals slated for global elimination. (panna.org)
  • In this study Mytilus edulis was used to investigate the effects of two pesticides, atrazine and lindane, which have different modes of action but produce similar changes in behaviour (depression of ventilation and feeding) in the mussels, and can cause starvation and mild hypoxia. (port.ac.uk)
  • In the present investigation, an attempt has been made to study the genotoxic effect of commonly used pesticides of South India, like 2,4-D, lindane, sevin and phosphamidon, in the human lymphocytes by comet assay and chromosomal analysis. (environmentportal.in)
  • IARC has evaluated the carcinogenicity of three pesticides: lindane (gamma-hexachlorocyclohexane), DDT (dichlorodiphenyltrichloroethane), and 2,4-D (2,4-dichlorophenoxyacetic acid). (occupationalcancer.ca)
  • But with these global parasites building a resistance to the strongest of pesticides, don't expect products containing lindane to vanish quickly from shelves, either. (wnd.com)
  • Pesticides that have been used in agriculture including lindane, dieldrin, DDT and endosulfan. (epa.ie)
  • Recommended Regimen - Permethrin cream (5%) applied to all areas of the body from the neck down and washed off after 8-14 hours, or Lindane (1%) 1 oz. of lotion or 30 g of cream applied thinly to all areas of the body from the neck down and washed off thoroughly after 8 hours. (cdc.gov)
  • A bioassay for possible carcinogenicity of lindane was conducted by administering the test chemical in the diet to Osborne-Mendel rats and B6C3F1 mice. (nih.gov)
  • This finding, by itself, is insufficient to establish the carcinogenicity of lindane. (nih.gov)
  • Lindane, also known as gamma-hexachlorocyclohexane (γ-HCH), gammaxene, Gammallin and benzene hexachloride (BHC), is an organochlorine chemical and an isomer of hexachlorocyclohexane that has been used both as an agricultural insecticide and as a pharmaceutical treatment for lice and scabies. (wikipedia.org)
  • In early September, California's Governor Gray Davis signed a bill prohibiting the sale or use of the pesticide lindane for treatment of lice and scabies. (panna.org)
  • Between 1972 and 1994, use of lindane to treat lice and scabies in U.S. children resulted in 88 reported cases of neurotoxicity and six deaths. (panna.org)
  • In addition to control of lice and scabies with medicated lotions and shampoos, common uses of lindane include seed and wood treatment and insecticidal spray for a number of food crops. (panna.org)
  • Permethrin is effective and safe but costs more than lindane. (cdc.gov)
  • Lindane-induced seizures in rats present a model of refractory generalized epilepsy. (org.rs)
  • H 2 S production inhibition aggravated lindane-induced seizures, revealing a functional relationship between H 2 S and the effects of lindane. (org.rs)
  • The aim of this study was to investigate the effects of H 2 S production inhibition using aminooxyacetate (a CBS inhibitor) on behavioral and EEG manifestations of lindane-induced seizures. (org.rs)
  • However, AOA significantly decreased the latency time and augmented the severity of lindane-induced seizures in a dose-dependent manner. (org.rs)
  • In rare cases, lindane has caused seizures and death. (wnd.com)
  • Seizures have occurred when lindane was applied after a bath or used by patients with extensive dermatitis. (cdc.gov)
  • The Pesticide Action Network reported: "Lindane is an antiquated and toxic pesticide that was once used extensively worldwide. (wnd.com)
  • Nolan K, Kamrath J, Levitt J. Lindane toxicity: a comprehensive review of the medical literature. (org.rs)
  • Evaluation of a two-generation reproduction toxicity study adding endpoints to detect endocrine disrupting activity using lindane. (bvsalud.org)
  • The production of the lindane isomers α- and β-hexachlorocyclohexane was also banned. (wikipedia.org)
  • According to a 1997 report from the Northern Contaminants Program, lindane and its isomers are found more often than any other organochlorine in the Arctic atmosphere and marine, terrestrial and freshwater environments. (panna.org)
  • Lindane is an organochlorine pesticide that is registered for use in soil, foliar, and seed treatment for a large variety of fruit and vegetable crops, and for use on livestock, pets, and agricultural premises. (nih.gov)
  • The warning emphasizes that Lindane products have been, and continue to be, indicated as a second-line therapy for the treatment of scabies and lice. (docnotes.net)
  • In increasing concentration, lindane first had the effect of a metabolizable foreign substance of the phenobarbital type, then a definite toxic action. (eurekamag.com)
  • The Environmental Protection Agency of the us has decided not to renew the registration of lindane, a highly toxic pesticide used to treat seeds of wheat, corn, oats, rye, barley and sorghum crops. (environmentportal.in)
  • In 2009, the production and agricultural use of lindane was banned under the Stockholm Convention on persistent organic pollutants. (wikipedia.org)
  • In 2009, an international ban on the use of lindane in agriculture was implemented under the Stockholm Convention on Persistent Organic Pollutants. (wikipedia.org)
  • Lindane is not, however, on the initial list of 12 persistent organic pollutants (POPs) slated for global elimination under the international treaty to control POPs. (panna.org)
  • Residues of lindane may be persistent in soil and foods. (nih.gov)
  • By the end of 1945, γ-hexachlorcyclohexane of 98% purity became available and ICI commercialised a seed treatment launched in 1949 as Mergamma A, containing 1% mercury and 20% lindane. (wikipedia.org)
  • There may also be direct human exposure to lindane through its use in pharmaceutical preparation or in public health pest control. (nih.gov)
  • Hence, a need was felt to investigate a effect of sublethal exposure of Organ chlorine pesticide Lindane to enzyme content of GOT, GPT, ALP, ACP and LDH in the liver, muscle and brain of freshwater fish Cyprinus carpio . (pharmaresearchlibrary.com)
  • It was found that GOT, GPT and LDH increased to the maximum level (after Lindane exposure) when compared to the controls (100%) and ACP,ALP were decreased from the control at 10, 20 and 30 days in the liver, muscle and brain, respectively at LC 50 exposure. (pharmaresearchlibrary.com)
  • In pressing for the California ban for public health uses, the L.A. County Sanitation Districts estimated the average cost to clean up lindane contamination at $250,000 per ounce, or $4,000 for the lindane rinsed from a single head lice treatment. (panna.org)
  • The ban, which will come into effect in 12-18 months, covers all agricultural and gardening applications of lindane. (panna.org)
  • Whether lindane is an endocrine disruptor is unclear. (wikipedia.org)
  • Between 1950 and 2000, an estimated 600,000 tonnes of lindane were produced globally, and the vast majority of which was used in agriculture. (wikipedia.org)
  • Lindane treatment was separated from control animals in a dose dependent way, and was associated with an increase in the concentration of alanine, and a decrease in all of the other identified metabolites (including osmolytes). (port.ac.uk)
  • Lindane is also a suspected carcinogen with possible links to breast cancer incidence, and has been found in breast milk and blood samples throughout the world. (panna.org)
  • Seizure incidence was higher in rats treated with aminooxyacetate (AOA) before lindane, but not significantly when compared with those treated only with lindane. (org.rs)
  • Lindane was classified as carcinogenic to humans (Group 1) based on sufficient evidence in humans that lindane causes non-Hodgkin lymphoma. (occupationalcancer.ca)
  • In the US, lindane pesticide products were regulated by the U.S. Environmental Protection Agency (EPA), while lindane medications are regulated by the Food and Drug Administration (FDA). (wikipedia.org)
  • Lindane medications continue to be available in the US, though since 1995, they have been designated "second-line" treatments, meaning they should be prescribed when other "first-line" treatments have failed or cannot be used. (wikipedia.org)
  • While FDA believes that the benefits of Lindane outweigh the risks when used as directed, given the potential for neurotoxicity, patients should only be treated with these medications if other treatments are not tolerable or other approved therapies have failed. (docnotes.net)
  • Groups of 50 rats of each sex were administered lindane at one of two doses for 80 weeks, then observed for 29-30 weeks. (nih.gov)
  • Neither the mean body weights of rats nor those of mice showed consistent effects from the administration of lindane. (nih.gov)
  • It is concluded that under the conditions of this bioassay, lindane was not carcinogenic for Osborne-Mendel rats or B6C3F1 mice. (nih.gov)
  • Male Wistar rats with previously implanted EEG electrodes were intraperitoneally (i.p.) treated with 4 mg/kg lindane and observed for convulsive behavior and EEG manifestations during the next 30 min. (org.rs)
  • EEG analysis revealed an increased number and duration of ictal periods in rats receiving AOA prior to lindane. (org.rs)
  • Hrnčić D, Rašić-Marković A, Djuric D, Šušić V, Stanojlović O. The Role of nitric oxide in convulsions induced by lindane in rats. (org.rs)
  • Groups of 50 mice of each sex were administered lindane at one of two doses, either 80 or 160 ppm, for 80 weeks, then observed for an additional 10-11 weeks. (nih.gov)
  • 7. Do not use other skin preparations such as creams, ointments, lotions, and oils along with Lindane. (stason.org)
  • Lindane kills parasites and their eggs. (stason.org)
  • Subsequently, lindane has been used to treat food crops and forestry products, as a seed or soil treatment, and to treat livestock and pets. (wikipedia.org)
  • since many sources (such as this 'tip' in American Family Physician) list Lindane as one of many treatment options - without advice about which product should be considered first-line and which should be reserved for resistant cases. (docnotes.net)
  • Initial deposits of lindane on green pods were 2.85 and 5.36 mg kg-1 at recommended and double dose, which dissipated with half-life of 3.3-3.6 days. (environmentportal.in)
  • 1. Before using this medication, tell your doctor if you are pregnant or breast-feeding or if you ever had a bad reaction to Lindane. (stason.org)
  • 2. If you are pregnant, wear gloves when applying Lindane to another person to prevent its absorption through your skin. (stason.org)
  • Lindane should not be used to treat premature infants, persons with a seizure disorder, women who are pregnant or breast-feeding, persons who have very irritated skin or sores where the lindane will be applied, infants, children, the elderly, and persons who weigh less than 110 pounds. (cdc.gov)
  • NOTE: Lindane should not be used following a bath, and it should not be used by persons with extensive dermatitis, pregnant or lactating women, and children less than 2 years of age. (cdc.gov)
  • Special Considerations Pregnant Women, Infants, and Young Children - Infants, young children, and pregnant and lactating women should not be treated with lindane. (cdc.gov)
  • We examined the influence of aminooxyacetate, an inhibitor of H 2 S production, when applied before lindane administration. (org.rs)
  • In December 2007, the FDA sent a Warning Letter to Morton Grove Pharmaceuticals, the sole U.S. manufacturer of lindane products, requesting that the company correct misleading information on two of its lindane websites. (wikipedia.org)
  • Labeling for Lindane products has been changed to include a boxed warning which highlights the most important safety issues associated with use of these products. (docnotes.net)
  • The National Pediculosis (headlice) Association recently established a database to track "adverse event" reports related to use of lindane to treat headlice in the United States. (panna.org)
  • The lindane (gamme-HCH) content shall be declared (not less than 988 g/kg) and, when determined, the average measured content shall not be lower than the declared minimum content. (who.int)
  • Maximum: 0.5% of the lindane content found under 2.2. (who.int)
  • National pesticide survey : Lindane. (epa.gov)
  • Lindane (58899), mirex (2385855), and dioxins were found in parts per billion concentrations in settled dust samples collected from rafters at all three industries, and substantial concentrations were found in sediment from an abandoned elevator shaft at NL Industries and in sediment from Bloody Creek Run as it flowed through a conduit under Greif Brothers Corporation. (cdc.gov)
  • Lindane is effective in most areas of the country, but lindane resistance has been reported in some areas of the world, including parts of the United States. (cdc.gov)
  • By November 2006, the use of lindane had been banned in 52 countries and restricted in 33 others. (wikipedia.org)
  • While lindane use continues in both industrialized and developing regions, all uses have been banned in at least 34 countries and at least 28 additional countries have severely restricted its use. (panna.org)
  • The POPs elimination treaty, which is scheduled to be signed by 120 or more countries early next year, could provide the vehicle for a global lindane ban. (panna.org)
  • Use of lindane is banned or restricted in most countries. (occupationalcancer.ca)
  • Allow your skin to dry and cool before applying lindane. (stason.org)
  • 3. Do not let Lindane touch your face, eyes, inflamed or raw skin, or open cuts. (stason.org)
  • In early 1999, a confidential EU report recommending the immediate withdrawal of lindane from the market was leaked to European pesticide activists. (panna.org)
  • 1. After using Lindane, machine-wash or dry clean all clothing, bed linen, and towels that you have used in the last two days. (stason.org)