Quality of Life: A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.Life: The state that distinguishes organisms from inorganic matter, manifested by growth, metabolism, reproduction, and adaptation. It includes the course of existence, the sum of experiences, the mode of existing, or the fact of being. Over the centuries inquiries into the nature of life have crossed the boundaries from philosophy to biology, forensic medicine, anthropology, etc., in creative as well as scientific literature. (Random House Unabridged Dictionary, 2d ed; Dr. James H. Cassedy, NLM History of Medicine Division)Life Change Events: Those occurrences, including social, psychological, and environmental, which require an adjustment or effect a change in an individual's pattern of living.Life Cycle Stages: The continuous sequence of changes undergone by living organisms during the post-embryonic developmental process, such as metamorphosis in insects and amphibians. This includes the developmental stages of apicomplexans such as the malarial parasite, PLASMODIUM FALCIPARUM.Life Tables: Summarizing techniques used to describe the pattern of mortality and survival in populations. These methods can be applied to the study not only of death, but also of any defined endpoint such as the onset of disease or the occurrence of disease complications.Life Support Care: Care provided patients requiring extraordinary therapeutic measures in order to sustain and prolong life.Questionnaires: Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.Life Style: Typical way of life or manner of living characteristic of an individual or group. (From APA, Thesaurus of Psychological Index Terms, 8th ed)Longevity: The normal length of time of an organism's life.Health Status: The level of health of the individual, group, or population as subjectively assessed by the individual or by more objective measures.Sickness Impact Profile: A quality-of-life scale developed in the United States in 1972 as a measure of health status or dysfunction generated by a disease. It is a behaviorally based questionnaire for patients and addresses activities such as sleep and rest, mobility, recreation, home management, emotional behavior, social interaction, and the like. It measures the patient's perceived health status and is sensitive enough to detect changes or differences in health status occurring over time or between groups. (From Medical Care, vol.xix, no.8, August 1981, p.787-805)Insurance, Life: Insurance providing for payment of a stipulated sum to a designated beneficiary upon death of the insured.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Activities of Daily Living: The performance of the basic activities of self care, such as dressing, ambulation, or eating.Personal Satisfaction: The individual's experience of a sense of fulfillment of a need or want and the quality or state of being satisfied.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Age Factors: Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.Stress, Psychological: Stress wherein emotional factors predominate.Psychometrics: Assessment of psychological variables by the application of mathematical procedures.Biogenesis: The origin of life. It includes studies of the potential basis for life in organic compounds but excludes studies of the development of altered forms of life through mutation and natural selection, which is BIOLOGICAL EVOLUTION.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Cross-Sectional Studies: Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Health Status Indicators: The measurement of the health status for a given population using a variety of indices, including morbidity, mortality, and available health resources.Adaptation, Psychological: A state of harmony between internal needs and external demands and the processes used in achieving this condition. (From APA Thesaurus of Psychological Index Terms, 8th ed)Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Depression: Depressive states usually of moderate intensity in contrast with major depression present in neurotic and psychotic disorders.Cost-Benefit Analysis: A method of comparing the cost of a program with its expected benefits in dollars (or other currency). The benefit-to-cost ratio is a measure of total return expected per unit of money spent. This analysis generally excludes consideration of factors that are not measured ultimately in economic terms. Cost effectiveness compares alternative ways to achieve a specific set of results.Life Support Systems: Systems that provide all or most of the items necessary for maintaining life and health. Provisions are made for the supplying of oxygen, food, water, temperature and pressure control, disposition of carbon dioxide and body waste. The milieu may be a spacecraft, a submarine, or the surface of the moon. In medical care, usually under hospital conditions, LIFE SUPPORT CARE is available. (From Webster's New Collegiate Dictionary)Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Socioeconomic Factors: Social and economic factors that characterize the individual or group within the social structure.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Terminal Care: Medical and nursing care of patients in the terminal stage of an illness.Sex Factors: Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.United StatesCohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.Cost of Illness: The personal cost of acute or chronic disease. The cost to the patient may be an economic, social, or psychological cost or personal loss to self, family, or immediate community. The cost of illness may be reflected in absenteeism, productivity, response to treatment, peace of mind, or QUALITY OF LIFE. It differs from HEALTH CARE COSTS, meaning the societal cost of providing services related to the delivery of health care, rather than personal impact on individuals.Human Development: Continuous sequential changes which occur in the physiological and psychological functions during the life-time of an individual.Biological Science Disciplines: All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.Mental Health: The state wherein the person is well adjusted.Anxiety: Feeling or emotion of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)Social Support: Support systems that provide assistance and encouragement to individuals with physical or emotional disabilities in order that they may better cope. Informal social support is usually provided by friends, relatives, or peers, while formal assistance is provided by churches, groups, etc.Beginning of Human Life: The point at which religious ensoulment or PERSONHOOD is considered to begin.Self Concept: A person's view of himself.Survivors: Persons who have experienced a prolonged survival after serious disease or who continue to live with a usually life-threatening condition as well as family members, significant others, or individuals surviving traumatic life events.Patient Satisfaction: The degree to which the individual regards the health care service or product or the manner in which it is delivered by the provider as useful, effective, or beneficial.Palliative Care: Care alleviating symptoms without curing the underlying disease. (Stedman, 25th ed)Outcome Assessment (Health Care): Research aimed at assessing the quality and effectiveness of health care as measured by the attainment of a specified end result or outcome. Measures include parameters such as improved health, lowered morbidity or mortality, and improvement of abnormal states (such as elevated blood pressure).Biological Evolution: The process of cumulative change over successive generations through which organisms acquire their distinguishing morphological and physiological characteristics.Caregivers: Persons who provide care to those who need supervision or assistance in illness or disability. They may provide the care in the home, in a hospital, or in an institution. Although caregivers include trained medical, nursing, and other health personnel, the concept also refers to parents, spouses, or other family members, friends, members of the clergy, teachers, social workers, fellow patients.Exobiology: The interdisciplinary science that studies evolutionary biology, including the origin and evolution of the major elements required for life, their processing in the interstellar medium and in protostellar systems. This field also includes the study of chemical evolution and the subsequent interactions between evolving biota and planetary evolution as well as the field of biology that deals with the study of extraterrestrial life.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Interpersonal Relations: The reciprocal interaction of two or more persons.Health Surveys: A systematic collection of factual data pertaining to health and disease in a human population within a given geographic area.Regression Analysis: Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.Reproduction: The total process by which organisms produce offspring. (Stedman, 25th ed)Terminally Ill: Persons with an incurable or irreversible illness at the end stage that will result in death within a short time. (From O'Leary et al., Lexikon: Dictionary of Health Care Terms, Organizations, and Acronyms for the Era of Reform, 1994, p780)Existentialism: Philosophy based on the analysis of the individual's existence in the world which holds that human existence cannot be completely described in scientific terms. Existentialism also stresses the freedom and responsibility of the individual as well as the uniqueness of religious and ethical experiences and the analysis of subjective phenomena such as anxiety, guilt, and suffering. (APA, Thesaurus of Psychological Index Terms, 8th ed.)Prevalence: The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.Wrongful Life: In civil law a cause of action which alleges that a defendant has wrongfully caused a child to be born.Spirituality: Sensitivity or attachment to religious values, or to things of the spirit as opposed to material or worldly interests. (from Merriam-Webster's Collegiate Dictionary, 10th ed, and Oxford English Dictionary, 2nd ed)Disabled Persons: Persons with physical or mental disabilities that affect or limit their activities of daily living and that may require special accommodations.Attitude to Death: Conceptual response of the person to the various aspects of death, which are based on individual psychosocial and cultural experience.Parents: Persons functioning as natural, adoptive, or substitute parents. The heading includes the concept of parenthood as well as preparation for becoming a parent.Analysis of Variance: A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Employment: The state of being engaged in an activity or service for wages or salary.Earth (Planet): Planet that is the third in order from the sun. It is one of the four inner or terrestrial planets of the SOLAR SYSTEM.Evolution, Chemical: Chemical and physical transformation of the biogenic elements from their nucleosynthesis in stars to their incorporation and subsequent modification in planetary bodies and terrestrial biochemistry. It includes the mechanism of incorporation of biogenic elements into complex molecules and molecular systems, leading up to the origin of life.Linear Models: Statistical models in which the value of a parameter for a given value of a factor is assumed to be equal to a + bx, where a and b are constants. The models predict a linear regression.Happiness: Highly pleasant emotion characterized by outward manifestations of gratification; joy.BrazilNetherlands: Country located in EUROPE. It is bordered by the NORTH SEA, BELGIUM, and GERMANY. Constituent areas are Aruba, Curacao, Sint Maarten, formerly included in the NETHERLANDS ANTILLES.Great BritainWithholding Treatment: Withholding or withdrawal of a particular treatment or treatments, often (but not necessarily) life-prolonging treatment, from a patient or from a research subject as part of a research protocol. The concept is differentiated from REFUSAL TO TREAT, where the emphasis is on the health professional's or health facility's refusal to treat a patient or group of patients when the patient or the patient's representative requests treatment. Withholding of life-prolonging treatment is usually indexed only with EUTHANASIA, PASSIVE, unless the distinction between withholding and withdrawing treatment, or the issue of withholding palliative rather than curative treatment, is discussed.Family: A social group consisting of parents or parent substitutes and children.Models, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Prenatal Exposure Delayed Effects: The consequences of exposing the FETUS in utero to certain factors, such as NUTRITION PHYSIOLOGICAL PHENOMENA; PHYSIOLOGICAL STRESS; DRUGS; RADIATION; and other physical or chemical factors. These consequences are observed later in the offspring after BIRTH.Phylogeny: The relationships of groups of organisms as reflected by their genetic makeup.Social Class: A stratum of people with similar position and prestige; includes social stratification. Social class is measured by criteria such as education, occupation, and income.Health Care Costs: The actual costs of providing services related to the delivery of health care, including the costs of procedures, therapies, and medications. It is differentiated from HEALTH EXPENDITURES, which refers to the amount of money paid for the services, and from fees, which refers to the amount charged, regardless of cost.Emotions: Those affective states which can be experienced and have arousing and motivational properties.Educational Status: Educational attainment or level of education of individuals.Social Behavior: Any behavior caused by or affecting another individual, usually of the same species.Holistic Health: Health as viewed from the perspective that humans and other organisms function as complete, integrated units rather than as aggregates of separate parts.Child Development: The continuous sequential physiological and psychological maturing of an individual from birth up to but not including ADOLESCENCE.Euthanasia: The act or practice of killing or allowing death from natural causes, for reasons of mercy, i.e., in order to release a person from incurable disease, intolerable suffering, or undignified death. (from Beauchamp and Walters, Contemporary Issues in Bioethics, 5th ed)Environment: The external elements and conditions which surround, influence, and affect the life and development of an organism or population.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Euthanasia, Passive: Failing to prevent death from natural causes, for reasons of mercy by the withdrawal or withholding of life-prolonging treatment.GermanyPhilosophy, MedicalProxy: A person authorized to decide or act for another person, for example, a person having durable power of attorney.Psychiatric Status Rating Scales: Standardized procedures utilizing rating scales or interview schedules carried out by health personnel for evaluating the degree of mental illness.Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.Statistics, Nonparametric: A class of statistical methods applicable to a large set of probability distributions used to test for correlation, location, independence, etc. In most nonparametric statistical tests, the original scores or observations are replaced by another variable containing less information. An important class of nonparametric tests employs the ordinal properties of the data. Another class of tests uses information about whether an observation is above or below some fixed value such as the median, and a third class is based on the frequency of the occurrence of runs in the data. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1284; Corsini, Concise Encyclopedia of Psychology, 1987, p764-5)Decision Making: The process of making a selective intellectual judgment when presented with several complex alternatives consisting of several variables, and usually defining a course of action or an idea.Social Environment: The aggregate of social and cultural institutions, forms, patterns, and processes that influence the life of an individual or community.Breast Feeding: The nursing of an infant at the breast.Self-Assessment: Appraisal of one's own personal qualities or traits.Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).Body Size: The physical measurements of a body.Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.Larva: Wormlike or grublike stage, following the egg in the life cycle of insects, worms, and other metamorphosing animals.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Social Adjustment: Adaptation of the person to the social environment. Adjustment may take place by adapting the self to the environment or by changing the environment. (From Campbell, Psychiatric Dictionary, 1996)Multivariate Analysis: A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.Exercise Therapy: A regimen or plan of physical activities designed and prescribed for specific therapeutic goals. Its purpose is to restore normal musculoskeletal function or to reduce pain caused by diseases or injuries.Birth Weight: The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms.Social Participation: Involvement in community activities or programs.Maternal Deprivation: Prolonged separation of the offspring from the mother.Pilot Projects: Small-scale tests of methods and procedures to be used on a larger scale if the pilot study demonstrates that these methods and procedures can work.Health: The state of the organism when it functions optimally without evidence of disease.Cognition: Intellectual or mental process whereby an organism obtains knowledge.Infant, Premature: A human infant born before 37 weeks of GESTATION.Age Distribution: The frequency of different ages or age groups in a given population. The distribution may refer to either how many or what proportion of the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.Motor Activity: The physical activity of a human or an animal as a behavioral phenomenon.Case-Control Studies: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.Markov Chains: A stochastic process such that the conditional probability distribution for a state at any future instant, given the present state, is unaffected by any additional knowledge of the past history of the system.Survival Analysis: A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.Self Report: Method for obtaining information through verbal responses, written or oral, from subjects.Self Care: Performance of activities or tasks traditionally performed by professional health care providers. The concept includes care of oneself or one's family and friends.Sex Distribution: The number of males and females in a given population. The distribution may refer to how many men or women or what proportion of either in the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Affect: The feeling-tone accompaniment of an idea or mental representation. It is the most direct psychic derivative of instinct and the psychic representative of the various bodily changes by means of which instincts manifest themselves.Mothers: Female parents, human or animal.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Oral Health: The optimal state of the mouth and normal functioning of the organs of the mouth without evidence of disease.Hospice Care: Specialized health care, supportive in nature, provided to a dying person. A holistic approach is often taken, providing patients and their families with legal, financial, emotional, or spiritual counseling in addition to meeting patients' immediate physical needs. Care may be provided in the home, in the hospital, in specialized facilities (HOSPICES), or in specially designated areas of long-term care facilities. The concept also includes bereavement care for the family. (From Dictionary of Health Services Management, 2d ed)Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.Fertility: The capacity to conceive or to induce conception. It may refer to either the male or female.Gestational Age: The age of the conceptus, beginning from the time of FERTILIZATION. In clinical obstetrics, the gestational age is often estimated as the time from the last day of the last MENSTRUATION which is about 2 weeks before OVULATION and fertilization.Models, Theoretical: Theoretical representations that simulate the behavior or activity of systems, processes, or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.Cause of Death: Factors which produce cessation of all vital bodily functions. They can be analyzed from an epidemiologic viewpoint.Euthanasia, Active: The act or practice of killing for reasons of mercy, i.e., in order to release a person or animal from incurable disease, intolerable suffering, or undignified death. (from Beauchamp and Walters, Contemporary Issues in Bioethics, 5th ed)EuropeAustralia: The smallest continent and an independent country, comprising six states and two territories. Its capital is Canberra.Double-Blind Method: A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.Demography: Statistical interpretation and description of a population with reference to distribution, composition, or structure.Mental Disorders: Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.Philosophy: A love or pursuit of wisdom. A search for the underlying causes and principles of reality. (Webster, 3d ed)Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.Pulmonary Disease, Chronic Obstructive: A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.Randomized Controlled Trials as Topic: Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.Canada: The largest country in North America, comprising 10 provinces and three territories. Its capital is Ottawa.Exercise: Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure.Qualitative Research: Any type of research that employs nonnumeric information to explore individual or group characteristics, producing findings not arrived at by statistical procedures or other quantitative means. (Qualitative Inquiry: A Dictionary of Terms Thousand Oaks, CA: Sage Publications, 1997)Patient Education as Topic: The teaching or training of patients concerning their own health needs.History, 19th Century: Time period from 1801 through 1900 of the common era.Survival Rate: The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.Evolution, Molecular: The process of cumulative change at the level of DNA; RNA; and PROTEINS, over successive generations.Breast Neoplasms: Tumors or cancer of the human BREAST.Dyspnea: Difficult or labored breathing.Sleep Disorders: Conditions characterized by disturbances of usual sleep patterns or behaviors. Sleep disorders may be divided into three major categories: DYSSOMNIAS (i.e. disorders characterized by insomnia or hypersomnia), PARASOMNIAS (abnormal sleep behaviors), and sleep disorders secondary to medical or psychiatric disorders. (From Thorpy, Sleep Disorders Medicine, 1994, p187)Sick Role: Set of expectations that exempt persons from responsibility for their illness and exempt them from usual responsibilities.Psychological Tests: Standardized tests designed to measure abilities, as in intelligence, aptitude, and achievement tests, or to evaluate personality traits.Cognition Disorders: Disturbances in mental processes related to learning, thinking, reasoning, and judgment.EnglandMarital Status: A demographic parameter indicating a person's status with respect to marriage, divorce, widowhood, singleness, etc.China: A country spanning from central Asia to the Pacific Ocean.JapanChi-Square Distribution: A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.Ecosystem: A functional system which includes the organisms of a natural community together with their environment. (McGraw Hill Dictionary of Scientific and Technical Terms, 4th ed)Geriatric Assessment: Evaluation of the level of physical, physiological, or mental functioning in the older population group.Sexual Dysfunction, Physiological: Physiological disturbances in normal sexual performance in either the male or the female.Data Collection: Systematic gathering of data for a particular purpose from various sources, including questionnaires, interviews, observation, existing records, and electronic devices. The process is usually preliminary to statistical analysis of the data.Models, Economic: Statistical models of the production, distribution, and consumption of goods and services, as well as of financial considerations. For the application of statistics to the testing and quantifying of economic theories MODELS, ECONOMETRIC is available.Spain: Parliamentary democracy located between France on the northeast and Portugual on the west and bordered by the Atlantic Ocean and the Mediterranean Sea.Personhood: The state or condition of being a human individual accorded moral and/or legal rights. Criteria to be used to determine this status are subject to debate, and range from the requirement of simply being a human organism to such requirements as that the individual be self-aware and capable of rational thought and moral agency.Medical Futility: The absence of a useful purpose or useful result in a diagnostic procedure or therapeutic intervention. The situation of a patient whose condition will not be improved by treatment or instances in which treatment preserves permanent unconsciousness or cannot end dependence on intensive medical care. (From Ann Intern Med 1990 Jun 15;112(12):949)Species Specificity: The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.Population Dynamics: The pattern of any process, or the interrelationship of phenomena, which affects growth or change within a population.Clinical Protocols: Precise and detailed plans for the study of a medical or biomedical problem and/or plans for a regimen of therapy.Hospitalization: The confinement of a patient in a hospital.Adaptation, Physiological: The non-genetic biological changes of an organism in response to challenges in its ENVIRONMENT.Single-Blind Method: A method in which either the observer(s) or the subject(s) is kept ignorant of the group to which the subjects are assigned.Obesity: A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).Psychology: The science dealing with the study of mental processes and behavior in man and animals.Patient Compliance: Voluntary cooperation of the patient in following a prescribed regimen.Body Mass Index: An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI=weight (kg)/height squared (m2). BMI correlates with body fat (ADIPOSE TISSUE). Their relationship varies with age and gender. For adults, BMI falls into these categories: below 18.5 (underweight); 18.5-24.9 (normal); 25.0-29.9 (overweight); 30.0 and above (obese). (National Center for Health Statistics, Centers for Disease Control and Prevention)Age of Onset: The age, developmental stage, or period of life at which a disease or the initial symptoms or manifestations of a disease appear in an individual.NorwayHome Care Services: Community health and NURSING SERVICES providing coordinated multiple services to the patient at the patient's homes. These home-care services are provided by a visiting nurse, home health agencies, HOSPITALS, or organized community groups using professional staff for care delivery. It differs from HOME NURSING which is provided by non-professionals.Religion: A set of beliefs concerning the nature, cause, and purpose of the universe, especially when considered as the creation of a superhuman agency. It usually involves devotional and ritual observances and often a moral code for the conduct of human affairs. (Random House Collegiate Dictionary, rev. ed.)Religion and Psychology: The interrelationship of psychology and religion.Residence Characteristics: Elements of residence that characterize a population. They are applicable in determining need for and utilization of health services.Infant Nutritional Physiological Phenomena: Nutritional physiology of children from birth to 2 years of age.Factor Analysis, Statistical: A set of statistical methods for analyzing the correlations among several variables in order to estimate the number of fundamental dimensions that underlie the observed data and to describe and measure those dimensions. It is used frequently in the development of scoring systems for rating scales and questionnaires.Child Psychology: The study of normal and abnormal behavior of children.Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.Urinary Incontinence: Involuntary loss of URINE, such as leaking of urine. It is a symptom of various underlying pathological processes. Major types of incontinence include URINARY URGE INCONTINENCE and URINARY STRESS INCONTINENCE.Urban Population: The inhabitants of a city or town, including metropolitan areas and suburban areas.Archaea: One of the three domains of life (the others being BACTERIA and Eukarya), formerly called Archaebacteria under the taxon Bacteria, but now considered separate and distinct. They are characterized by: (1) the presence of characteristic tRNAs and ribosomal RNAs; (2) the absence of peptidoglycan cell walls; (3) the presence of ether-linked lipids built from branched-chain subunits; and (4) their occurrence in unusual habitats. While archaea resemble bacteria in morphology and genomic organization, they resemble eukarya in their method of genomic replication. The domain contains at least four kingdoms: CRENARCHAEOTA; EURYARCHAEOTA; NANOARCHAEOTA; and KORARCHAEOTA.Health Behavior: Behaviors expressed by individuals to protect, maintain or promote their health status. For example, proper diet, and appropriate exercise are activities perceived to influence health status. Life style is closely associated with health behavior and factors influencing life style are socioeconomic, educational, and cultural.Fetal Development: Morphological and physiological development of FETUSES.Cross-Cultural Comparison: Comparison of various psychological, sociological, or cultural factors in order to assess the similarities or diversities occurring in two or more different cultures or societies.Health Status Disparities: Variation in rates of disease occurrence and disabilities between population groups defined by socioeconomic characteristics such as age, ethnicity, economic resources, or gender and populations identified geographically or similar measures.Personal Autonomy: Self-directing freedom and especially moral independence. An ethical principle holds that the autonomy of persons ought to be respected. (Bioethics Thesaurus)Rural Population: The inhabitants of rural areas or of small towns classified as rural.Personality: Behavior-response patterns that characterize the individual.
  • The Earth BioGenome Project aims to sequence the DNA of all known eukaryotic species on Earth, a massive group that includes plants, animals, fungi and other organisms. (ucdavis.edu)
  • Project AIMS. (ed.gov)
  • Project AIMS (Activities to Integrate Mathematics and Science) has as its purpose the integration of subject matter in grades K-9. (ed.gov)
  • It's not currently available in the UK but we spoke to Owlet on the show floor and it told us that it aims to release it after July 2018. (which.co.uk)
  • In 2018, 10 million people fell ill with TB worldwide and 1.5 million people lost their lives to this disease. (orissadiary.com)
  • 23-2-2018 · I remain the official Senior Maverick for Wired, a magazine aim essay in easy my life I helped co-found 25 years ago. (feetcare.nu)
  • 12-1-2018 · Timberwolves' Jamal Crawford promotes Black History Month initiative, takes aim at Trump. (feetcare.nu)
  • Reata founder Warren Huff had some advice for interested life sciences entrepreneurs: "You need to be very realistic about the scientific prospects. (xconomy.com)
  • While the North Texas biotech entrepreneurial scene is in its early stages, the region is home to large life sciences companies whose employees could help seed startup ventures. (xconomy.com)
  • Brett Giroir, the former CEO of the Texas A&M University Health Science Center and now an advisor to TMCx, the Texas Medical Center's accelerator in Houston, said those efforts could help North Texas also build a life sciences community that was "more than the sum of its parts. (xconomy.com)
  • CEO and CSO of Tiziana Life Sciences . (proactiveinvestors.com)
  • Another eventful week for New England's life sciences companies, with big changes potentially in store for two of the biggest firms. (xconomy.com)
  • Science China Life Sciences is an academic journal cosponsored by the Chinese Academy of Sciences and the National Natural Science Foundation of China, and published by Science China Press. (springer.com)
  • Life Sciences , 255 , 117743. (unboundmedicine.com)
  • Cellular and Molecular Life Sciences - incl. (springer.com)
  • Based in Basel, Switzerland, the multidisciplinary journal Cellular and Molecular Life Sciences (CMLS) publishes research articles, reviews, multi-author reviews and visions & reflections articles covering the latest aspects of biological and biomedical research. (springer.com)
  • 2012-02-A new study from Karolinska Institute and Umeå University finds that non-pharmacological care in the last days of a patient's life, known as palliative care, is not as simplistic as one may think. (umu.se)
  • The new recommendation from ASTRO advises to use the addition of concurrent chemotherapy along with palliative thoracic radiation therapy only for highly selected patients with stage 3 NSCLC, including those who are deemed incurable by their treating physicians, are candidates for chemotherapy, have an Eastern Cooperative Oncology Group, more commonly known as ECOG, performance status between zero and two and have a life expectancy of at least three months. (curetoday.com)
  • However, palliative care occurs principally during the last week of life and a high burden of unnecessary drugs is still found on the day of death. (springer.com)
  • A single-center retrospective cohort study included older adults (≥ 65 years) who died in a teaching hospital between 1 January 2014 and 30 June 2014 and had been identified as patients in need of palliative care in their last 3 months of life. (springer.com)
  • Near the end of life, medication therapy is adapted to the goals of palliative care. (springer.com)
  • Van Nordennen RT, Lavrijsen JC, Heesterbeek MJ, Vissers KC, Koopmans RT (2016) Changes in prescribed drugs between admission and the end of life in patients admitted to palliative care facilities. (springer.com)
  • We welcome guest posts about pro life news. (liveaction.org)
  • The Pro-Life Alliance, a coalition of "nontraditional" organizations that have banded together for the protection of the unborn, held its first news conference an hour before the March for Life rally began. (catholic-sf.org)
  • Upon starting the news conference, Murphy reiterated the group's stance to unite "atheists, pagans, Buddhists, Muslims and Jews" on the issue of the sanctity of human life and dignity. (catholic-sf.org)
  • Heparin, the life saving blood thinner used in major surgeries and treatment of heart diseases, is a complicated drug but a research team from the University of British Columbia has set out to make its use a lot safer by developing a universal antidote. (eurekalert.org)
  • Researchers have made potentially life-changing suggestions to improve wait times, including performing elective surgeries later in the day and addressing delays around patient transfer from smaller hospitals. (cbc.ca)
  • Researchers aim to treat more patients within 24 hours to reduce major complications. (cbc.ca)
  • The dementia survival probability tool, developed by researchers at Sweden's Karolinska Institute and from the Netherlands, aims to give a better indication of severity of the disease at the point of diagnosis. (aol.co.uk)
  • Researchers aim to assemble the tree of life for all 2 million nam. (bio-medicine.org)
  • But despite significant progress in fleshing out the major branches of the tree of life, today there is still no central place where researchers can go to browse and download the entire tree. (bio-medicine.org)
  • This newsletter highlights recent research by National Institute on Aging-supported researchers and others who are examining two aspects of well-being-how older people evaluate their daily lives and how they experience their daily lives. (prb.org)
  • Well-being measures could help researchers identify groups of older adults who are at risk of poor health and evaluate interventions to improve their lives. (prb.org)
  • People who play an instrument will often have learned the basics in early childhood, but brain researchers from Hanover and Geneva want to show that music lessons can be valuable even later in life. (dw.com)
  • Researchers have shown they can grow the dormant parasite in engineered human liver tissue for several weeks, allowing them to closely study how the parasite becomes dormant, what vulnerabilities it may have, and how it springs back to life. (technologynetworks.com)
  • CEO Ron Ranauro explained how the unprecedented rate at which researchers are generating genetic data and life science companies' growing reliance on cloud computing are coming together to boost demand for GenomeQuest's technology, which researchers use to analyze and manage the genetic information during drug development and other biomedical research. (xconomy.com)
  • It's rechargeable and Owlet claims you'll get 18 hours of battery life. (which.co.uk)
  • Extending the battery life cycle is therefore a crucial aspect in improving EVs' contribution to overall sustainable development. (mdpi.com)
  • Even though most people say they want to stay home and avoid stress and discomfort near the end of life, health care interventions tend to increase dramatically during the final months, often producing little benefit and much suffering. (commonwealthfund.org)
  • These results provide evidence for the effectiveness of goal-focused, community-based experiential life skills interventions to support skill development in youth with a disability and help them prepare for transition to adult life. (nih.gov)
  • hear important facts and understand the work children's hospitals are doing to fight sepsis and save lives. (cdc.gov)
  • You can read more about pediatric sepsis and how children's hospitals are working together to save lives. (cdc.gov)
  • TB preventive treatment works synergistically with antiretroviral therapy to prevent TB and save lives. (orissadiary.com)
  • The groups in the alliance include Life Matters Journal, Feminists for Nonviolent Choices, New Wave Feminists, Secular Pro-Life, And Then There Were None - Pro-Life Outreach, Democrats for Life of America and Consistent Life, with more groups "who will be signing on in the days and months to come. (catholic-sf.org)
  • Other speakers from groups such as New Wave Feminists and the Democrats for Life of America followed Murphy in stating their desire to create a culture of life across all walks of life. (catholic-sf.org)
  • We hypothesised that nutritional taurine, which is important for the development of the endocrine pancreas and reduces cytokine-induced apoptosis in pancreatic beta cells, would prevent or delay the onset of autoimmune diabetes, if given early in life to the non-obese diabetic (NOD) mouse. (springer.com)
  • Van Den Noortgate NJ, Verhofstede R, Cohen J, Piers RD, Deliens L, Smets T (2016) Prescription and deprescription of medication during the last 48 hours of life: Multicenter study in 23 acute geriatric wards in Flanders Belgium. (springer.com)
  • The lectures build on the 1st year "Principles of Life 1" module. (bangor.ac.uk)
  • What makes the study very complicated is that we aim to examine how the brain functions in later stages of life and what effects music and theoretical music lessons in control groups have on brain structure and brain networks. (dw.com)
  • A multisite study of term and near term infants readmitted in the first two weeks of life to 9 New York City area hospitals in 1995 was conducted to evaluate factors related to readmission, including length of newborn stay. (nih.gov)
  • The aim of this study was to determine if nutritional taurine supplementation to the NOD mouse in early life could alter the morphology of the developing endocrine pancreas, change the degree of insulitis in later life, and delay the onset of diabetes. (springer.com)
  • The aim of this study was to explore older workers' motivation for a full or extended working life. (cambridge.org)
  • This study highlights the preferential prescription of essential drugs and deprescription of unnecessary drugs during the last 3 months of life in older adults. (springer.com)
  • Measuring the burden of medications in older adults near the end of life: Nationwide, longitudinal cohort study. (springer.com)
  • It collects data with an end-of-life questionnaire (ELQ), which is validated in this study. (diva-portal.org)
  • Study I - The aim was to examine the validity of the ELQ from the SRPC. (diva-portal.org)
  • The aim of this study is to explore the knowledge about critically ill children and recognition of those for employees. (regionh.dk)
  • Yet meditation, as it was traditionally conceived, was intended to be a life-long practice, the benefits of which were not necessarily expected to manifest in the short term. (hindawi.com)
  • There is little empirical evidence about the effectiveness of life skills programs in preparing youth with disabilities for successful participation in adult life. (nih.gov)
  • That unit had developed a computerized end-of-life medical record module that enabled a comparison between reported data and medical records, illustrating the validity of the registry questionnaire. (diva-portal.org)
  • Thanks in large part to advances in DNA sequencing, thousands of new phylogenetic trees are published in scientific journals each year most of them focused on isolated branches of the tree of life, for everything from birds to botflies. (bio-medicine.org)
  • The discovery of the bona fide shape of the IgM pentamer advances our structural understanding of the pentameric IgM and its binding mode with AIM. (sciencemag.org)
  • Alfie Evans was taken off life-support treatment on Monday. (itv.com)
  • Alfie, who doctors say has a degenerative neurological condition, was taken off life-support treatment on Monday. (itv.com)
  • Alfie has been at the centre of a life-or-death treatment battle, with his parents trying to block doctors from withdrawing life support in a sometimes acrimonious six-month dispute which has seen a series of court battles. (itv.com)
  • How do treatment aims in the last phase of life relate to hospitalizations and hospital mortality? (ru.nl)
  • A basic knowledge of the building blocks of life (metabolites) and how they are made via metabolic pathways, also the implications of this to nutrition and treatment of disease (infectious, acquired and inherited). (bangor.ac.uk)
  • The Dragonfly team hopes to learn whether combining organic material with liquid water and energy in the form of heat could have caused complex molecules to develop - or even life itself. (voanews.com)
  • He thanked supporters but asked them to 'return back to your everyday lives' as he and partner Kate James work on forming a relationship with Alder Hey Hospital. (itv.com)
  • He accused doctors at the hospital of being "wrong" about their diagnosis: "Alfie lives, comfortably, happily, without ventilation, without any form of ventilation. (itv.com)
  • The aim is to reduce sepsis deaths and hospital-onset severe sepsis by at least 75 percent. (cdc.gov)
  • Jennifer Neve's brother Michael lives at the Civic campus of the Ottawa Hospital. (cbc.ca)
  • That was the goal last week at a conference sponsored by the newly reconstituted Bio North Texas, an advocacy group that is promoting life science commercialization in the Dallas-Fort Worth area. (xconomy.com)
  • There really is a lot more going on here" when you stop to take a look, says Melissa Knauth, a principal in life science investments for 2M, the family office of Dallas executive Morton Meyerson. (xconomy.com)
  • Critters: K-6 Life Science Activities. (ed.gov)
  • But now, thanks to a three-year, $5.76 million grant from the U.S. National Science Foundation, a team of scientists and developers from ten universities aims to make that a reality. (bio-medicine.org)
  • Scientists think that the heat from the collision that formed the crater would have liquefied the water ice in Titan's crust, creating an environment with all the necessary components for life. (voanews.com)
  • Created jointly by Drayson Technologies and scientists from Imperial College London, the aim is to more efficiently power technologies across architecture, furniture, wearables and more. (cityam.com)
  • A second table aimed at specialist clinics includes specific sub-types of dementia, such as Alzheimer's disease, allowing doctors to get an idea of how likely it is that the patient will die within three years of diagnosis. (aol.co.uk)
  • Molecular Biology: To introduce the central roles for large molecules in all life on earth. (bangor.ac.uk)
  • Studies on Stem Cells Research and Therapy aims to publish current hottest topics in stem cell research as well as stem cells therapies that have been shown to be safe and effective. (peertechz.com)
  • SSCRT also aims to publish manuscripts that put light on how painstaking and difficult is to Identify, isolate and grow the right kind of stem cell, particularly in the case of rare adult stem cells. (peertechz.com)
  • Carden credits having a baby at age 29 with saving her life because it forced her to quit the drug abuse and get clean. (myplainview.com)
  • If we can develop our understanding of this 'social life' of proteins, significant strides could be made in drug discovery. (technologynetworks.com)
  • The most prescribed and deprescribed drug classes were, respectively, analgesics (56.4%) and antithrombotic agents (38.2%) during the last week of life. (springer.com)
  • One thing its instruments will be on the lookout for is a class of molecules called amino acids, which are found in all life on Earth. (voanews.com)
  • If amino acids are present on Titan, Dragonfly should be able to tell if there are unequal amounts of left- and right-handed varieties - a sign that life is present on the frozen surface. (voanews.com)
  • We therefore sought to alter pancreatic islet development in early life to increase beta cell mass using the amino acid taurine, which has been shown to have mitogenic and anti-apoptotic actions on beta cells, and through this determine if this delayed the onset of diabetes. (springer.com)
  • Murphy went on to say that "alienation of nontraditional groups in the pro-life movement has made them inactive and apathetic" and that the pro-life movement is better served by "remaining united in diversity, rather than creating division by infighting. (catholic-sf.org)
  • Who has made a major impact in your post-stroke life? (strokeassociation.org)
  • An appreciation of the ethical and social issues raised by the orhtodox explanation of the origin of life and of genetic engineering. (bangor.ac.uk)