The number of WHITE BLOOD CELLS per unit volume in venous BLOOD. A differential leukocyte count measures the relative numbers of the different types of white cells.
White blood cells. These include granular leukocytes (BASOPHILS; EOSINOPHILS; and NEUTROPHILS) as well as non-granular leukocytes (LYMPHOCYTES and MONOCYTES).
A transient increase in the number of leukocytes in a body fluid.
Movement of tethered, spherical LEUKOCYTES along the endothelial surface of the microvasculature. The tethering and rolling involves interaction with SELECTINS and other adhesion molecules in both the ENDOTHELIUM and leukocyte. The rolling leukocyte then becomes activated by CHEMOKINES, flattens out, and firmly adheres to the endothelial surface in preparation for transmigration through the interendothelial cell junction. (From Abbas, Cellular and Molecular Immunology, 3rd ed)
The number of PLATELETS per unit volume in a sample of venous BLOOD.
The number of LEUKOCYTES and ERYTHROCYTES per unit volume in a sample of venous BLOOD. A complete blood count (CBC) also includes measurement of the HEMOGLOBIN; HEMATOCRIT; and ERYTHROCYTE INDICES.
A peripheral blood picture resembling that of leukemia or indistinguishable from it on the basis of morphologic appearance alone. (Dorland, 27th ed)
Granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.
The number of RED BLOOD CELLS per unit volume in a sample of venous BLOOD.
The movement of leukocytes in response to a chemical concentration gradient or to products formed in an immunologic reaction.
The number of CD4-POSITIVE T-LYMPHOCYTES per unit volume of BLOOD. Determination requires the use of a fluorescence-activated flow cytometer.
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
A plasma protein that circulates in increased amounts during inflammation and after tissue damage.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
Elements of limited time intervals, contributing to particular results or situations.
Measurement of rate of settling of erythrocytes in anticoagulated blood.
The volume of packed RED BLOOD CELLS in a blood specimen. The volume is measured by centrifugation in a tube with graduated markings, or with automated blood cell counters. It is an indicator of erythrocyte status in disease. For example, ANEMIA shows a low value; POLYCYTHEMIA, a high value.
INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.
Leukemia associated with HYPERPLASIA of the lymphoid tissues and increased numbers of circulating malignant LYMPHOCYTES and lymphoblasts.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
The number of LYMPHOCYTES per unit volume of BLOOD.
Leukocytes with abundant granules in the cytoplasm. They are divided into three groups according to the staining properties of the granules: neutrophilic, eosinophilic, and basophilic. Mature granulocytes are the NEUTROPHILS; EOSINOPHILS; and BASOPHILS.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
A watery fluid that is continuously produced in the CHOROID PLEXUS and circulates around the surface of the BRAIN; SPINAL CORD; and in the CEREBRAL VENTRICLES.
The preparation of leukocyte concentrates with the return of red cells and leukocyte-poor plasma to the donor.
The number of CELLS of a specific kind, usually measured per unit volume or area of sample.
Colorless to yellow dye that is reducible to blue or black formazan crystals by certain cells; formerly used to distinguish between nonbacterial and bacterial diseases, the latter causing neutrophils to reduce the dye; used to confirm diagnosis of chronic granulomatous disease.
A clinical syndrome characterized by repeated spontaneous hemorrhages and a remarkable increase in the number of circulating platelets.
A hydrolase enzyme that converts L-asparagine and water to L-aspartate and NH3. EC 3.5.1.1.
White blood cells formed in the body's lymphoid tissue. The nucleus is round or ovoid with coarse, irregularly clumped chromatin while the cytoplasm is typically pale blue with azurophilic (if any) granules. Most lymphocytes can be classified as either T or B (with subpopulations of each), or NATURAL KILLER CELLS.
The soft tissue filling the cavities of bones. Bone marrow exists in two types, yellow and red. Yellow marrow is found in the large cavities of large bones and consists mostly of fat cells and a few primitive blood cells. Red marrow is a hematopoietic tissue and is the site of production of erythrocytes and granular leukocytes. Bone marrow is made up of a framework of connective tissue containing branching fibers with the frame being filled with marrow cells.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Disease having a short and relatively severe course.
Tests used in the analysis of the hemic system.
A proteinase inhibitor found in various BODILY SECRETIONS that coat mucosal surfaces such as SEMINAL PLASMA; CERVICAL MUCUS; and bronchial secretions. It plays a role in protecting epithelial tissues from LEUKOCYTE-derived serine proteases such as NEUTROPHIL ELASTASE.
A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.
Adherence of cells to surfaces or to other cells.
A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by CYTOKINES arising from the abnormal clone.
An enzyme that catalyzes the hydrolysis of proteins, including elastin. It cleaves preferentially bonds at the carboxyl side of Ala and Val, with greater specificity for Ala. EC 3.4.21.37.
The minute vessels that collect blood from the capillary plexuses and join together to form veins.
Therapeutic act or process that initiates a response to a complete or partial remission level.
Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.
A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.
Granular leukocytes with a nucleus that usually has two lobes connected by a slender thread of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and stainable by eosin.
A cytokine that stimulates the growth and differentiation of B-LYMPHOCYTES and is also a growth factor for HYBRIDOMAS and plasmacytomas. It is produced by many different cells including T-LYMPHOCYTES; MONOCYTES; and FIBROBLASTS.
A classification of lymphocytes based on structurally or functionally different populations of cells.
The transfer of leukocytes from a donor to a recipient or reinfusion to the donor.
Large, phagocytic mononuclear leukocytes produced in the vertebrate BONE MARROW and released into the BLOOD; contain a large, oval or somewhat indented nucleus surrounded by voluminous cytoplasm and numerous organelles.
An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
Cell adhesion molecule and CD antigen that mediates the adhesion of neutrophils and monocytes to activated platelets and endothelial cells.
The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
An abnormal elevation of body temperature, usually as a result of a pathologic process.
Differentiation antigens residing on mammalian leukocytes. CD stands for cluster of differentiation, which refers to groups of monoclonal antibodies that show similar reactivity with certain subpopulations of antigens of a particular lineage or differentiation stage. The subpopulations of antigens are also known by the same CD designation.
Method of analyzing chemicals using automation.
Enumeration by direct count of viable, isolated bacterial, archaeal, or fungal CELLS or SPORES capable of growth on solid CULTURE MEDIA. The method is used routinely by environmental microbiologists for quantifying organisms in AIR; FOOD; and WATER; by clinicians for measuring patients' microbial load; and in antimicrobial drug testing.
A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.
Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.
Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.
Cell-surface glycoprotein beta-chains that are non-covalently linked to specific alpha-chains of the CD11 family of leukocyte-adhesion molecules (RECEPTORS, LEUKOCYTE-ADHESION). A defect in the gene encoding CD18 causes LEUKOCYTE-ADHESION DEFICIENCY SYNDROME.
A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.
A peptide hormone that lowers calcium concentration in the blood. In humans, it is released by thyroid cells and acts to decrease the formation and absorptive activity of osteoclasts. Its role in regulating plasma calcium is much greater in children and in certain diseases than in normal adults.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Rare, autosomal recessive disorder caused by deficiency of the beta 2 integrin receptors (RECEPTORS, LEUKOCYTE-ADHESION) comprising the CD11/CD18 family of glycoproteins. The syndrome is characterized by abnormal adhesion-dependent functions, especially defective tissue emigration of neutrophils, leading to recurrent infection.
The relationship between the dose of an administered drug and the response of the organism to the drug.
Controlled operation of an apparatus, process, or system by mechanical or electronic devices that take the place of human organs of observation, effort, and decision. (From Webster's Collegiate Dictionary, 1993)
An encapsulated lymphatic organ through which venous blood filters.
The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.
An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.
A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472)
Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites.
Assays that measure the rate of migration of LEUKOCYTES. They may involve a variety of techniques such as measuring the movement of leukocytes through substrates such as AGAROSE gels or the rate of exit of cells from a glass capillary.
Proteins prepared by recombinant DNA technology.
The transference of BONE MARROW from one human or animal to another for a variety of purposes including HEMATOPOIETIC STEM CELL TRANSPLANTATION or MESENCHYMAL STEM CELL TRANSPLANTATION.
The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.
A cell-surface ligand involved in leukocyte adhesion and inflammation. Its production is induced by gamma-interferon and it is required for neutrophil migration into inflamed tissue.
A count of SPERM in the ejaculum, expressed as number per milliliter.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of LEUKEMIA and other NEOPLASMS.
Toxins closely associated with the living cytoplasm or cell wall of certain microorganisms, which do not readily diffuse into the culture medium, but are released upon lysis of the cells.
Washing liquid obtained from irrigation of the lung, including the BRONCHI and the PULMONARY ALVEOLI. It is generally used to assess biochemical, inflammatory, or infection status of the lung.
Test for cell-mediated antitumor immunity and related serum blocking factors based on the finding that leukocytes from cancer patients, but not from controls, when mixed in vitro with antigenic extracts of tumors of the same histological type, undergo a diminution in their normal adherence to glass surfaces. Sera from tumor-bearing patients block the LAI reaction of their own leukocytes or those of other patients with the same type of tumor.
Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.
A member of the CXC chemokine family that plays a role in the regulation of the acute inflammatory response. It is secreted by variety of cell types and induces CHEMOTAXIS of NEUTROPHILS and other inflammatory cells.
The measure of the level of heat of a human or animal.
An examination of chemicals in the blood.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
The engulfing and degradation of microorganisms; other cells that are dead, dying, or pathogenic; and foreign particles by phagocytic cells (PHAGOCYTES).
Cell adhesion molecule and CD antigen that serves as a homing receptor for lymphocytes to lymph node high endothelial venules.
Antigens determined by leukocyte loci found on chromosome 6, the major histocompatibility loci in humans. They are polypeptides or glycoproteins found on most nucleated cells and platelets, determine tissue types for transplantation, and are associated with certain diseases.
Surface ligands, usually glycoproteins, that mediate cell-to-cell adhesion. Their functions include the assembly and interconnection of various vertebrate systems, as well as maintenance of tissue integration, wound healing, morphogenic movements, cellular migrations, and metastasis.
The measurement of an organ in volume, mass, or heaviness.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
Cell adhesion molecule and CD antigen that mediates neutrophil, monocyte, and memory T-cell adhesion to cytokine-activated endothelial cells. E-selectin recognizes sialylated carbohydrate groups related to the Lewis X or Lewis A family.
The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.
Infections by bacteria, general or unspecified.
Process of classifying cells of the immune system based on structural and functional differences. The process is commonly used to analyze and sort T-lymphocytes into subsets based on CD antigens by the technique of flow cytometry.
The return of a sign, symptom, or disease after a remission.
A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
Substances that reduce the growth or reproduction of BACTERIA.
An integrin heterodimer widely expressed on cells of hematopoietic origin. CD11A ANTIGEN comprises the alpha chain and the CD18 antigen (ANTIGENS, CD18) the beta chain. Lymphocyte function-associated antigen-1 is a major receptor of T-CELLS; B-CELLS; and GRANULOCYTES. It mediates the leukocyte adhesion reactions underlying cytolytic conjugate formation, helper T-cell interactions, and antibody-dependent killing by NATURAL KILLER CELLS and granulocytes. Intracellular adhesion molecule-1 has been defined as a ligand for lymphocyte function-associated antigen-1.
A class of statistical methods applicable to a large set of probability distributions used to test for correlation, location, independence, etc. In most nonparametric statistical tests, the original scores or observations are replaced by another variable containing less information. An important class of nonparametric tests employs the ordinal properties of the data. Another class of tests uses information about whether an observation is above or below some fixed value such as the median, and a third class is based on the frequency of the occurrence of runs in the data. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1284; Corsini, Concise Encyclopedia of Psychology, 1987, p764-5)
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
Mapping of the KARYOTYPE of a cell.
Progenitor cells from which all blood cells derive.
Infection of the lung often accompanied by inflammation.
The development and formation of various types of BLOOD CELLS. Hematopoiesis can take place in the BONE MARROW (medullary) or outside the bone marrow (HEMATOPOIESIS, EXTRAMEDULLARY).
The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.
An adhesion-promoting leukocyte surface membrane heterodimer. The alpha subunit consists of the CD11b ANTIGEN and the beta subunit the CD18 ANTIGEN. The antigen, which is an integrin, functions both as a receptor for complement 3 and in cell-cell and cell-substrate adhesive interactions.
Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.
Family of proteins associated with the capacity of LEUKOCYTES to adhere to each other and to certain substrata, e.g., the C3bi component of complement. Members of this family are the LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; (LFA-1), the MACROPHAGE-1 ANTIGEN; (Mac-1), and the INTEGRIN ALPHAXBETA2 or p150,95 leukocyte adhesion protein. They all share a common beta-subunit which is the CD18 antigen. All three of the above antigens are absent in inherited LEUKOCYTE-ADHESION DEFICIENCY SYNDROME, which is characterized by recurrent bacterial infections, impaired pus formation, and wound healing as well as abnormalities in a wide spectrum of adherence-dependent functions of granulocytes, monocytes, and lymphoid cells.
A graphic means for assessing the ability of a screening test to discriminate between healthy and diseased persons; may also be used in other studies, e.g., distinguishing stimuli responses as to a faint stimuli or nonstimuli.
Transmembrane proteins consisting of a lectin-like domain, an epidermal growth factor-like domain, and a variable number of domains that are homologous to complement regulatory proteins. They are important cell adhesion molecules which help LEUKOCYTES attach to VASCULAR ENDOTHELIUM.
The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.
Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.
An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.
Portable peritoneal dialysis using the continuous (24 hours a day, 7 days a week) presence of peritoneal dialysis solution in the peritoneal cavity except for periods of drainage and instillation of fresh solution.
Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
Cells contained in the bone marrow including fat cells (see ADIPOCYTES); STROMAL CELLS; MEGAKARYOCYTES; and the immediate precursors of most blood cells.
Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.
Glycoproteins found in a subfraction of normal mammalian plasma and urine. They stimulate the proliferation of bone marrow cells in agar cultures and the formation of colonies of granulocytes and/or macrophages. The factors include INTERLEUKIN-3; (IL-3); GRANULOCYTE COLONY-STIMULATING FACTOR; (G-CSF); MACROPHAGE COLONY-STIMULATING FACTOR; (M-CSF); and GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; (GM-CSF).
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
Inhaling and exhaling the smoke of burning TOBACCO.
The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
An infant during the first month after birth.
Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS).
Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN.
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.
Therapy with two or more separate preparations given for a combined effect.
Substances that inhibit or prevent the proliferation of NEOPLASMS.
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
The portion of the descending aorta proceeding from the arch of the aorta and extending to the DIAPHRAGM, eventually connecting to the ABDOMINAL AORTA.
A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA.
The number of RETICULOCYTES per unit volume of BLOOD. The values are expressed as a percentage of the ERYTHROCYTE COUNT or in the form of an index ("corrected reticulocyte index"), which attempts to account for the number of circulating erythrocytes.
Antibodies produced by a single clone of cells.
The circulation of the BLOOD through the MICROVASCULAR NETWORK.
Cytokine-induced cell adhesion molecule present on activated endothelial cells, tissue macrophages, dendritic cells, bone marrow fibroblasts, myoblasts, and myotubes. It is important for the recruitment of leukocytes to sites of inflammation. (From Pigott & Power, The Adhesion Molecule FactsBook, 1993, p154)
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
Determination of parasite eggs in feces.
Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Phenomenon of cell-mediated immunity measured by in vitro inhibition of the migration or phagocytosis of antigen-stimulated LEUKOCYTES or MACROPHAGES. Specific CELL MIGRATION ASSAYS have been developed to estimate levels of migration inhibitory factors, immune reactivity against tumor-associated antigens, and immunosuppressive effects of infectious microorganisms.
The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.

Monocyte-mediated antibody-dependent cellular cytotoxicity: a clinical test of monocyte function. (1/7223)

The lack of a simple, rapid, and quantitative test of the functional activity of the monocyte has hampered studies of the contribution of this cell type to host defense and human disease. This report describes an assay of antibody-dependent cellular cytotoxicity, which depends exclusively upon the monocyte as the effector cell and therefore provides a convenient test of monocyte function. In this system, mononuclear leukocytes (MNL) obtained by Ficoll-Hypaque separation of whole blood are cytotoxic for 51Cr-labeled human erythrocyte targets coated with anti-blood group antibody. Removal of phagocytic monocytes from the MNL by iron ingestion, followed by exposure to a magnetic field, completely abolishes all cytotoxic activity from the remaining MNL population. Similarly, in severely mono-cytopenic patients with aplastic anemia, cytotoxic effector activity is absent. In normals and less severely monocytopenic aplastic anemia patients, cytotoxicity correlates significantly (p less than 0.001) with monocyte number. Application of this monocyte-mediated antibody-dependent cellular cytotoxicity assay to the study of patients with the Wiskott-Aldrich syndrome has revealed defective monocyte cytotoxic activity in spite of normal monocyte numbers, suggesting that this test may be useful for the assessment of monocyte function in a variety of clinical situations.  (+info)

Antitumor agents. I. Effect of 5-fluorouracil and cyclophosphamide on liver microsomes and thymus of rat. (2/7223)

Effects of antitumor agents on rat liver microsomal drug-metabolizing enzyme activities and thymus lymphocytes were studied in male Wistar rats. High doses of 5-fluorouracil (5-FU) and cyclophosphamide (CP) given parenterally for 6 days caused a partial decrease in whole body weight and the microsomal enzyme content such as cytochrome P-450 and cytochrome b5. Aniline p-hydroxylase and aminopyrine N-demethylase activities also decreased in rats dosed for 5 days decreased compared with the control. Both compounds in the high concentrations produced spectral change of "modified type II". However, the magnitude of the spectral changes observed was independent of the the concentration of substrate added. The addition of NADPH to the microsomes-substrate mixture modified the spectral change. Both drugs caused a considerable decrease in thymus weight and the number of thymus lymphocytes, while the alkaline phosphatase activity was enhanced in 5-FU groups, indicating that the agents cause a significant involution of the thymus. Decrease in the total number of the lymphocytes was greater than that in the blood leucocytes.  (+info)

Optimizing aminoglycoside therapy for nosocomial pneumonia caused by gram-negative bacteria. (3/7223)

Nosocomial pneumonia is a notable cause of morbidity and mortality and leads to increases in lengths of hospital stays and institutional expenditures. Aminoglycosides are used to treat patients with these infections, but few data on the doses and schedules required to achieve optimal therapeutic outcomes exist. We analyzed aminoglycoside treatment data for 78 patients with nosocomial pneumonia to determine if optimization of aminoglycoside pharmacodynamic parameters results in a more rapid therapeutic response (defined by outcome and days to leukocyte count resolution and temperature resolution). Cox proportional hazards, Classification and Regression Tree (CART), and logistic regression analyses were applied to the data. By all analyses, the first measured maximum concentration of drug in serum (Cmax)/MIC predicted days to temperature resolution and the second measured Cmax/MIC predicted days to leukocyte count resolution. For days to temperature resolution and leukocyte count resolution, CART analyses produced breakpoints, with an 89% success rate at 7 days of therapy for a Cmax/MIC of > 4.7 and an 86% success rate at 7 days of therapy for a Cmax/MIC of > 4.5, respectively. Logistic regression analyses predicted a 90% probability of temperature resolution and leukocyte count resolution by day 7 if a Cmax/MIC of > or = 10 is achieved within the first 48 h of aminoglycoside therapy. Aggressive aminoglycoside dosing immediately followed by individualized pharmacokinetic monitoring would ensure that Cmax/MIC targets are achieved early in therapy. This would increase the probability of a rapid therapeutic response for pneumonia caused by gram-negative bacteria and potentially decreasing durations of parenteral antibiotic therapy, lengths of hospitalization, and institutional expenditures, a situation in which both the patient and the institution benefit.  (+info)

Increase of hematopoietic responses by triple or single helical conformer of an antitumor (1-->3)-beta-D-glucan preparation, Sonifilan, in cyclophosphamide-induced leukopenic mice. (4/7223)

It has been suggested that the immunopharmacological activity of soluble (1-->3)-beta-D-glucan depends on its conformation in mice. In this study, we examined the relationship between the conformation of Sonifilan (SPG) and hematopietic responses in cyclophosphamide (Cy)-induced leukopenic mice. SPG, a high molecular weight (1-->3)-beta-D-glucan, has a triple helical conformation in water, and it was changed by treatment with aqueous sodium hydroxide to the single helical conformer (SPG-OH). The effects of SPG or SPG-OH on hematopoietic responses in cyclophosphamide induced leukopenic mice were investigated by monitoring i) gene expression of cytokines by RT-PCR, ii) protein synthesis of interleukin 6 (IL-6) by ELISA and iii) colony formation of bone marrow cells (BMC). The mice administered Cy and SPG or SPG-OH expressed and produced higher levels of IL-6 mRNA and protein than the mice administered only Cy. Gene expression of NK1.1 was also induced by Cy/SPG (or SPG-OH) treatment. Induced gene expression of stem cell factor (SCF) and macrophage-colony stimulating factor (M-CSF) by SPG/SPG-OH were also found in in vitro culture of BMC from Cy treated mice. These results strongly suggested that conformation of the glucans, single and triple helix, are independent of the hematopietic response.  (+info)

An epidemiological study on the association between the total leukocyte and neutrophil counts, and risk factors of ischemic heart disease by smoking status in Japanese factory workers. (5/7223)

Several epidemiologic studies have shown the association between total leukocyte count and the risk of developing myocardial infarction. The purpose of this study was to assess the association between the total leukocyte and neutrophil counts and risk factors of ischemic heart disease in 1,384 Japanese factory workers. Total leukocyte and neutrophil counts were significantly higher in current smokers than in non-smokers. Among current smokers, the total leukocyte and neutrophil counts were positively associated with the number of cigarettes smoked daily and the duration of cigarette smoking and alcohol consumption. Being independent of smoking habit, the total leukocyte and neutrophil counts were also related to several characteristics recorded at the physical examinations. The total leukocyte and neutrophil counts were positively associated with serum total cholesterol, serum triglyceride and hematocrit levels, and inversely associated with the serum HDL-cholesterol level. No significant associations of the total leukocyte or neutrophil counts were found with the red blood cell count and hemoglobin level. These results suggest that the total leukocyte and neutrophil counts may represent the metabolic condition with a high coronary risk among apparently healthy people.  (+info)

The effect of age and teat order on alpha1-acid glycoprotein, neutrophil-to-lymphocyte ratio, cortisol, and average daily gain in commercial growing pigs. (6/7223)

The objectives of the study were to evaluate age and teat order on a performance trait, average daily gain, and on physiological stress indicators, alpha1-acid glycoprotein (AGP), neutrophil-to-lymphocyte ratio (N:L), and cortisol in commercial growing pigs from weaning to market age. Pigs (n = 129) from five commercial California farms were weighed and blood-sampled at 28-d intervals from 28 to 168 d of age. Laboratory assays were performed from blood samples to quantify cortisol, AGP, and N:L. Age and facility effects (P<.001), but not teat order effects (P>.05), were found for all three physiological traits and ADG. Pigs that routinely suckled from teats 1, 4, or 6 (numbered from anterior to posterior on the upper teat bank) had similar (P>.05) ADG and BW throughout the production cycle. No correlation (P> .05) was found between cortisol, AGP, and N:L. The use of these physiological and production traits as stress and health indices of growing pigs in commercial facilities has limitations in comparing data between facilities or different ages of pigs.  (+info)

Early infection in bone marrow transplantation: quantitative study of clinical factors that affect risk. (7/7223)

Infections remain common life-threatening complications of bone marrow transplantation. To examine clinical factors that affect infection risk, we retrospectively studied patients who received bone marrow transplants (53 autologous and 51 allogeneic). Over a median of 27 hospital days, 44 patients developed documented infections. Both autologous transplantation and hematopoietic growth factor use were associated with less prolonged neutropenia and decreased occurrence of infection (P < or = .05). In a survival regression model, variables independently associated with infection risk were the log10 of the neutrophil count (hazard ratio [HR], 0.49; 95% confidence interval [CI], 0.32-0.75), ciprofloxacin prophylaxis (HR, 0.42; 95% CI, 0.19-0.95), empirical intravenous antibiotic use (HR, 0.09; 95% CI, 0.03-0.32), and an interaction between neutrophil count and intravenous antibiotic use (HR, 1.86; 95% CI, 1.06-3.29). In this model, infection risk increases steeply at low neutrophil counts for patients receiving no antibiotic therapy. Ciprofloxacin prophylaxis and particularly intravenous antibiotic therapy provide substantial protection at low neutrophil counts. These results can be used to model management strategies for transplant recipients.  (+info)

Airway inflammatory response to ozone in subjects with different asthma severity. (8/7223)

The aim of this study was to evaluate whether ozone exposure induces a similar airway inflammatory response in subjects with different degrees of asthma severity. Two groups of asthmatic subjects were studied: seven with intermittent mild asthma not requiring regular treatment (group A); and seven with persistent mild asthma requiring regular treatment with inhaled corticosteroids and long-acting beta2-agonists (group B). All subjects were exposed, in a randomized cross-over design, to air or O3 (0.26 parts per million (ppm) for 2 h with intermittent exercise); subjects in group B withdrew from regular treatment 72 h before each exposure. Before the exposure, and 1 and 2 h after the beginning of the exposure they performed a pulmonary function test, and a questionnaire was completed to obtain a total symptom score (TSS). Six hours after the end of the exposure, hypertonic saline (HS) sputum induction was conducted. Sputum cell percentages, eosinophil cationic protein (ECP) and interleukin (IL)-8 concentrations in the sputum supernatant were measured. TSS significantly increased and forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) significantly decreased after O3 exposure in comparison with air exposure in group A, whereas no changes were observed in group B except for a significant decrement of FEV1 2 h after the beginning of O3 exposure. Sputum neutrophil percentage was significantly higher after O3 exposure than after air exposure in both groups (Group A: 70.2% (28-87) versus 26.6% (8.6-73.2); Group B: 62.1% (25-82.4) versus 27.9% (14.4-54)). IL-8 was higher in sputum supernatant collected 6 h after O3 exposure than after air, only in group A. No change due to O3 has been found in sputum eosinophil percentage and ECP concentration in both groups. In conclusion, the degree of airway response to a short-term exposure to ozone is different in subjects with asthma of different severity. The available data do not allow elucidation of whether this difference depends on the severity of the disease or on the regular anti-inflammatory treatment.  (+info)

Question - Can costochrondritis cause elevated white blood cell count?. Ask a Doctor about when and why Complete blood count is advised, Ask a General & Family Physician
There are several possible causes for a high white blood cell count. This count is high when there are more disease-fighting cells in your body. The technical term for this condition is leukocytosis.. Different medical practices may have different limits by which they define high white blood cell count. A count of 10,500 leukocytes in one microliter of blood is widely accepted as a high count. The threshold may vary between sex and age.. White blood cells are categorized by five subtypes, and each type has a different activity in fighting disease. When you get the results of your white blood cell count, they will usually specify what the levels are of all the different types. Usually, a high count is only caused by an increase in one type of white blood cells.. A high white blood cell count is indicative of an immune system problem that increases their production; a disease in your bone marrow that causes high blood cell production; a reaction to some drug that is used to enhance cell ...
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Abstract. Objective: To determine the correlation between differential leukocyte counts and hyperglycemic emergencies.. Methods: Fifty patients with diabetic ketoacidosis (DKA), 50 patients with diabetic ketosis (DK), 50 non-DK diabetic patients with stable glycemic control, and 50 normal controls were enrolled. Their total and differential leukocyte counts were measured and evaluated at admission and after treatment.. Results: The patients with DKA and DK had higher plasma glucose levels (20.84±6.73 mmol/L, 15.55±2.6 mmol/L, respectively) and more median leukocytes (13325/mm3 and 6595/mm3, respectively) and median neutrophils (11124 /mm3 and 4125/mm3, respectively) but fewer median eosinophils (28/mm3 and 72/mm3, respectively) compared to non-DK and control groups (all p , 0.05). Acute infection increased the elevating extent. The median leukocyte counts in DK and non-DK patients (6595/mm3 and 6008/mm3, respectively) were within the normal range. The counts of total leukocytes and neutrophils ...
Inflammation is increasingly recognized as having an important role in patients with acute coronary syndromes. We sought to determine whether an elevated white blood cell (WBC) count would predict subsequent mortality and whether revascularization would have a protective effect. We analyzed data from 10,480 patients with acute coronary syndromes enrolled in the PURSUIT trial who had a WBC count measured on admission. WBC count values were stratified by quartiles, and death rates at 6 months were examined in univariate and multivariate analyses. Propensity analysis was performed to assess the effect of revascularization on the relation between WBC count and mortality. In the lowest quartile of WBC count, mortality was 4.0%; it was 5.8% in the second quartile, 6.7% in the third quartile, and 8.0% in the fourth quartile (p ...
Comparison of the Predictive Strength of Total White Blood Cell Count Within 24 Hours on Outcome of Traumatic Brain Injury with Glasgow Coma Score and Pupillary Reactivity
This study examined the effects of palm carotene feeding on DNA damage of bone marrow, recovery of peripheral leukocyte counts, and the survival of mice that received whole-body X-ray irradiation. The palm carotene was composed of alpha- and beta-carotene in a ratio of 1:3. Mice were fed either a basal diet or a carotene diet (50 mg carotene/100 g diet) for 2 weeks, then irradiated. The carotene diet was prepared by the dietary protocol that markedly enhanced the accumulation of carotene in tissues (J. Nutr. 125, 3081, 1995). DNA damage in bone marrow was evaluated by micronucleus assay using peripheral blood. When mice received X-ray (1.5 Gy), marked DNA damage in bone marrow and reduction of peripheral leukocyte count were observed. These changes were significantly attenuated in mice fed the carotene diet. In addition, X-ray (6.5 Gy)-induced survival of mice fed the carotene diet was higher than those fed the basal diet. In mice fed the carotene diet, alpha- and beta-carotene were detected in ...
ABSTRACT Aims: The aim of the present study is to investigate systemic levels of inflammatory markers of cardiovascular diseases like C-reactive protein (CRP), interleukin-6 (IL-6), total leukocyte count and differential count in patients with chronic periodontitis, in comparison to healthy individuals without periodontal disease.
Low Monocyte count is also known as Monocytopenia and it refers to the abnormal decrease of Monocytes in the circulating blood.. The normal white blood cell count of Monocytes ranges between 1100 cells/µL (5.8% of differential white blood cells count) in infants to300 cells/µL (4% of differential white blood cells count) in adults.. In addition to the main causes of Leukopenia, low Monocytes count can be a result of acute stress or glucocorticoid administration.. Immunosuppressive agents (drugs that reduce the production of white cells) and overwhelming infections will decrease the count of Monocytes in the blood.. ...
You know from one of our previous articles that white blood cell count or total leukocyte count is a test which we perform to get the count of white blood cells in our blood. With the help of this test, we find the different ranges of leukocytes presiding in our body and if there are different … [Read more...] ...
Objective: We hypothesized that a single value of leukocyte count, on admission might be a helpful predictor to prognosticate the clinical outcome and plan the management (early delivery versus conservative management) in patients presenting with pre term pre-labour rupture of membranes (PPROM).. Design: Observational study.. Setting: This study was conducted in a tertiary care centre.. Population or sample: 127 pregnancies complicated with PPROM.. Method: A novel scoring system was devised depending upon the final clinical performance. Main outcome measure: Adverse fetal, neonatal and maternal outcome.. Result: Based on the score cut off for the total leukocyte count was calculated to prognosticate the outcome. Leukocyte count of 15,850/mm3, at the time of admission was found to be able to predict the clinical outcome with a sensitivity of 85.7% and specificity of 87.6%, in a case of PPROM. Whereas the individual components of differential leukocyte counts were found to be not of much help in ...
White blood cell (WBC) count has been associated with diabetic risk, but whether the correlation is independent of other risk factors has hardly been studied. Moreover, very few such studies with large sample sizes have been conducted in Chinese. Therefore, we investigated the relationship between WBC count and glucose metabolism in china. We also examined the relevant variables of WBC count. A total of 9,697 subjects (mean age, 58.0 ± 9.1 years) were recruited. The subjects were classified into four groups, including subjects with normal glucose tolerance, isolated impaired fasting glucose, impaired glucose tolerance and type 2 diabetes mellitus (T2DM). We found that WBC count increased as glucose metabolism disorders exacerbated. WBC count was also positively correlated with waist hip ratio, body mass index, smoking, triglycerides, glycosylated haemoglobin A1c (HbA1c) and 2-h postprandial glucose. In addition, high density lipoprotein and the female gender were inversely correlated with WBC count. In
Leukocyte Differential Counting application generating alerts for every 100 cells counted by adding erythroblasts out of the total count.
Alternative treatments for high white blood cell count - My white blood cell count was 6.25... Is this normal or low? Is it okay to take prednisone for poison ivy with this WBC count? Youre fine. Normal WBC. I trust lymphocyte and neutrophil counts were fine also. Take the prenisone for the poison ivy only if its so bad you cant sleep otherwise. Were glad to help.
Free, official coding info for 2018 ICD-10-CM D72.829 - includes detailed rules, notes, synonyms, ICD-9-CM conversion, index and annotation crosswalks, DRG grouping and more.
No Triple Crown, and now no rubber match.Kentucky Derby winner Nyquist and Preakness victor Exaggerator will not meet for the sixth time June 11 in the 148th Belmont Stakes. After blood work taken Mon
The most dangerous thing that is associated with this disease is that it affects the bodys ability to fight infections. A person effected with a leucopenia have a tremendous decrease in the number of total white blood cells (leukocytes) found in blood. It is also known as leukocytopenia. The normal total white cell count is 5000-10000 per cubic millimeter. If the total white cell count drops below 3,500 per cubic millimeter in the blood, the person is said to be suffering from leucopenia. ...
Low white blood cell count colon cancer - My husband has colon cancer, his tumor and section of colon were removed yesterday. He has an elevated white blood cell count but no fever. Problem? See below. All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, the elevated white cell count is likely a normal reaction to the trauma of surgery. If he has fever, discharge from the surgical site, pain at the surgical site, then you should consult your doctor promptly.
The purpose of the present study was twofold: (1) to determine if X-irradiation can be considered a direct stress agent, and if so, to what extent it differs from other stressors; and (2) to further elucidate the role of the adrenal cortex in the radiation syndrome by determining the more immediate responses of this system to X-irradiation.
CONTEXT: Impaired fetal growth is associated with increased risk for coronary heart disease and diabetes in adulthood, but the underlying mechanism is unclear. OBJECTIVE: The objective of the study was to examine the relation between early growth (weight at birth and first year) and adult total leukocyte count, the primary cell effectors of inflammation. DESIGN: This was a birth cohort study (Northern Finland Birth Cohort 1966) with participants prospectively and longitudinally followed up from birth to age 31 yr. SETTING: This was a general population-based cohort in Finland. PARTICIPANTS: A total of 5619 offspring of expectant mothers who attended a clinical examination and blood draw at 31-yr follow-up (4486 with complete data on weight at 1 yr) participated in the study. MAIN EXPOSURE VARIABLES: Weight at birth and at 1 year. MAIN OUTCOME MEASURE: Absolute leukocyte count was measured. RESULTS: Total leukocyte count was lower at higher birth weight categories with or without adjustments for adult
I have an almost 6 year old daughter who over the last few years has had numerous high fevers with a high white blood cell count with no other symptoms of signs of infection. March 2009 she had a feve...
About 8 months ago my doctor told me i had a high white blood cell count in my liver i would imagine thats from 6 plus years of using. I never went back to see her. Now that ive been clean for awhile i...
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QScout - MLD - Milk Leukocyte Differential by Advanced Animal Diagnostics, Inc.. QScout MLD (milk leukocyte differential) test identifies and differentiates leukocytes, or white blood cells, in milk. QScout Farm Lab reads the test, looking for elevat...
Is there any link between high white blood cells and cancer? Yes, high WBC count indicates various types of illnesses. But before going to know the link, you should understand the complete blood picture.
Answer (1 of 6): I have cancer so I know what you are talking about. A high white blood count is a sign of cancer because the body is trying to fight off the disease. I did not know about a low white blood count. Thank you rayoflight for that information. I learned something new today.
Virchow spoke of a physiologic leukocytosis of pregnancy, and by the weight of his authority the assumption was given validity, repeated in textbooks, but as far as can be found out, never very seriously investigated. De Lee1 elaborates the idea by stating that during pregnancy, from the first few months, there is a decrease of the red blood cells and an increase of the white blood cells, the latter out of proportion to the former yet seldom exceeding 15,000; that the younger forms increase so that the blood of pregnancy resembles that in an acute infectious disease, and further that ...
Dairy cows are highly susceptible to infectious diseases, like mastitis, during the period around calving. Although factors contributing to increased susceptibility to infection have not been fully elucidated, impaired neutrophil recruitment to the site of infection and changes in the concentrations of some micronutrients related with the function of the immune defence has been implicated. Most of the current information is based on studies outside the Nordic countries where the conditions for dairy cows are different. Therefore, the aim of the study was to evaluate changes in blood concentrations of the vitamins A and E, the minerals calcium (Ca), phosphorous (P), and magnesium (Mg), the electrolytes potassium (K) and sodium (Na) and the trace elements selenium (Se), copper (Cu) and zinc (Zn), as well as changes in total and differential white blood cell counts (WBC) and expression of the adhesion molecules CD62L and CD18 on blood neutrophils in Swedish dairy cows during the period around calving.
Usually, in reports of clinical or laboratory data, the substance per se is not reported; rather, a value is given that was obtained by measuring a substance or some function or constituent of it. For example, one does not report hemoglobin but hemoglobin level. Some other correct forms are as follows: differential white blood cell count agglutination titer prothrombin time pulse rate erythrocyte sedimentation rate total serum cholesterol value or level or concentration increase in antibody level creatinine level or clearance serum phosphorus concentration increase in bilirubin level platelet count 24-hour urine output or volume antinuclear antibody titer mean corpuscular
Usually, in reports of clinical or laboratory data, the substance per se is not reported; rather, a value is given that was obtained by measuring a substance or some function or constituent of it. For example, one does not report hemoglobin but hemoglobin level. Some other correct forms are as follows: differential white blood cell count agglutination titer prothrombin time pulse rate erythrocyte sedimentation rate total serum cholesterol value or level or concentration increase in antibody level creatinine level or clearance serum phosphorus concentration increase in bilirubin level platelet count 24-hour urine output or volume antinuclear antibody titer mean corpuscular
White blood cells, representing approximately 1 percent of the blood, provide resistance against infection and disease. Causes of low white blood count include viral infection, cancer, HIV, chronic...
Your white blood cell count may be high because your body is fighting an infection. But other things can cause it, such as some medicines, burns, an illness, or other health problems. When your doctor sees that your white blood cell count is high, he or she will try to find out why, and then treat the cause.. ...
A count of the number of white blood cells per unit volume in venous blood. A differential leukocyte count measures the relative numbers of the different types of white cells.
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The normal range for a white blood cell count can vary from person to person. Low blood cell counts can lead to serious complications that may delay your next
Your strategy: If blood tests reveal that your white-cell count is over 10,000 cells per microliter, ask for a CT scan of your stomach. The white blood cell count is a very soft indicator of appendicitis. It can be normal in more than 10% of cases and an elevated white blood cell count is non-specific. The white blood cell count can be elevated in many diseases that are not appendicitis ...
The blood delivers leukocytes to the various tissues from the bone marrow, where they are produced. Normal blood leukocyte counts are 4.3-10.8 × 109/L, with neutrophils representing 45-74% of the cells, bands 0-4%, lymphocytes 16-45%, monocytes 4-10%, eosinophils 0-7%, and basophils 0-2%. Variation among individuals and among different ethnic groups can be substantial, with lower leukocyte numbers for certain African-American ethnic groups. The various leukocytes are derived from a common stem cell in the bone marrow. Three-fourths of the nucleated cells of bone marrow are committed to the production of leukocytes. Leukocyte maturation in the marrow is under the regulatory control of a number of different factors, known as colony-stimulating factors (CSFs) and interleukins (ILs). Because an alteration in the number and type of leukocytes is often associated with disease processes, total white blood cell (WBC) count (cells per μL) and differential counts are informative. This chapter focuses on ...
A lytic agent is described which when mixed with whole blood, lyses the red cells instantly, but does not affect the optical, light scattering properties of the white blood cells for at least 30 seconds. This lytic agent enables the performance of a five part leukocyte differential by flow cytometry and light scattering. In its preferred embodiment, the lytic agent incorporates 2-phenoxyethanol which combines the functions of leukoprotective and antimicrobial, TRITON X-100 (octylphenoxypolyethoxyethanol) a lytic and wetting agent and TRIS/HCl to provide pH buffering and to increase the solutions conductivity.
Result column: The result column shows counts that fall within the normal range.. Flag column: The flag column shows counts that are lower (L) or higher (H) than the normal range.. Reference Interval (or Reference Range) column: The reference interval shows the normal range for each measurement for the lab performing the test. Different labs may use different reference intervals.. White blood cells: White blood cells help protect individuals from infections. The above CBC report shows that the patients total white cell count is 1.5, which is lower than the normal range of 4.0-10.5. The low white cell count increases the risk of infection.. Differential: This portion of the CBC shows the counts for the 5 main kinds of white cells, either as percentages (the first 5 counts), or as the absolute number of cells (the second 5 counts).. Absolute neutrophil count: Neutrophils are the main white blood cell for fighting or preventing bacterial or fungal infections. In the CBC report, neutrophils may ...
White blood cell (WBC) count is a common clinical measure from complete blood count assays, and it varies widely among healthy individuals. Total WBC count and its constituent subtypes have been shown to be moderately heritable, with the heritability estimates varying across cell types. We studied 19,509 subjects from seven cohorts in a discovery analysis, and 11,823 subjects from ten cohorts for replication analyses, to determine genetic factors influencing variability within the normal hematological range for total WBC count and five WBC subtype measures. Cohort specific data was supplied by the CHARGE, HeamGen, and INGI consortia, as well as independent collaborative studies. We identified and replicated ten associations with total WBC count and five WBC subtypes at seven different genomic loci (total WBC count-6p21 in the HLA region, 17q21 near ORMDL3, and CSF3; neutrophil count-17q21; basophil count- 3p21 near RPN1 and C3orf27; lymphocyte count-6p21, 19p13 at EPS15L1; monocyte count-2q31 at ITGA4,
White blood cell count (leukocyte count): The number of white blood cells (WBCs) in the blood. The WBC is usually measured as part of the CBC (complete blood count). White blood cells are the infection-fighting cells in the blood and are distinct from the red (oxygen-carrying) blood cells known as erythrocytes. There are different types of white blood cells, including neutrophils (polymorphonuclear leukocytes; PMNs), band cells (slightly immature neutrophils), T-type lymphocytes (T cells), B-type lymphocytes (B cells), monocytes, eosinophils, and basophils. All the types of white blood cells are reflected in the white blood cell count. The normal range for the white blood cell count varies between laboratories but is usually between 4,300 and 10,800 cells per cubic millimeter of blood. This can also be referred to as the leukocyte count and can be expressed in international units as 4.3 - 10.8 x 109 cells per liter. ...
Hello Belgium! An elevated white blood cell count with high neutrophils and intermittent fevers could indicate some type of infection. Its difficult for me to advise you on what to do next without...
In my thesis I focused on comparing a differential leukocyte count (DIF) determined by the analyzer and by microscope in the group of pediatric oncological and hemato-oncological patients. Thesis is divided into theoretical and practical parts. The theoretical part includes an explanation of the process of hematopoiesis, the development of blood cells and the characteristic of time series, a decription of hemato-oncological and oncological diseases which occur most frequently in the monitored group of pediatric patients, and their treatment. In a practical part is described a determination of the DIF by the analyzer Beckman Coulter LH 750 and by microscope Meopta. I measured a blood count with the differencial leukocyte count, I made a blood smear and I evaluated microscopically it, in the selected group of pediatric patients. The results were reported in the tables and statistically processed using paired t-test in GraphPad Prism and were created graphs. An aim of this thesis was to explore and ...
I took care of a trauma patient a few months ago who was in a motor vehicle crash on her prom night. Initial imaging showed some left sided rib fractures and a broken leg. She was admitted to the regular nursing floor for further observation. When I saw her in the morning (4 hours after arrival) I found that she had one of those classic seat belt signs. She was also was quite tender on abdominal exam. Her labs revealed an elevated white blood cell count, in itself not necessarily a concerning thing as young trauma patients with broken limbs will often mount a reactive leukocytosis. But her abdominal exam bothered me. I reviewed the CT with the radiologist. She didnt see anything unusual. So I repeated the CT and the blood work 2 hours later. Her WBC count was now over 20. The CT scan, however, was again read as normal. When I examined her, she had frank peritonitis ...
PRIMARY OBJECTIVES:. I. To determine the maximum tolerated dose (MTD) of recombinant human IL15 (rhIL15) administered subcutaneously.. SECONDARY OBJECTIVES:. I. To determine the effect of the dose schedules of rhIL15 on the number and phenotype of peripheral blood mononuclear cells including: total white blood cell count; absolute lymphocyte count (ALC); and total number of T cells and natural killer (NK) cells, as well as activated T cells, T cell subsets and NK cell subsets.. II. To determine the effects of the dose schedules of rhIL15 on the function of peripheral blood mononuclear cells including: T cell subset response to recall viral antigens including cytomegalovirus (CMV) and influenza A virus; T cell responses to non-physiologic stimuli including: phytohemagglutinin (PHA); and NK cell cytokine (interferon gamma [IFN-y]) secretion and degranulation by cluster of differentiation 107a (CD107a) expression.. III. To assess tumor response rate by objective response rate (ORR). IV. To assess ...
PRIMARY OBJECTIVES:. I. To determine the maximum tolerated dose (MTD) of recombinant human IL15 (rhIL15) administered subcutaneously.. SECONDARY OBJECTIVES:. I. To determine the effect of the dose schedules of rhIL15 on the number and phenotype of peripheral blood mononuclear cells including: total white blood cell count; absolute lymphocyte count (ALC); and total number of T cells and natural killer (NK) cells, as well as activated T cells, T cell subsets and NK cell subsets.. II. To determine the effects of the dose schedules of rhIL15 on the function of peripheral blood mononuclear cells including: T cell subset response to recall viral antigens including cytomegalovirus (CMV) and influenza A virus; T cell responses to non-physiologic stimuli including: phytohemagglutinin (PHA); and NK cell cytokine (interferon gamma [IFN-y]) secretion and degranulation by cluster of differentiation 107a (CD107a) expression.. III. To assess tumor response rate by objective response rate (ORR). IV. To assess ...
My dad is in the Hospital going on 12 days now, he originally went in with a pain in his lower back and some masive chronic Hiccups. This topic is answered by a medical expert.
This study aimed to evaluate the effect of heat stress on quail hematological parameters. A total number of 300 Japanese quail chicks (Coturnix Coturnix japonica) of 28 days old were exposed to different levels of raising temperatures (22, 29, 34, 36 and 40 ºC) for 15 days. At 42 days old, blood samples were collected from 14 birds (7 males + 7 females) that were randomly selected. The samples were used for determining red blood cells count, hemoglobin concentration, packed cell volume, total and differential white blood cells count, heterophils/ lymphocyte (H/L) ratio, mean corpuscular hemoglobin, mean corpuscular volume and mean corpuscular hemoglobin concentration. The obtained results indicated that, rearing quail birds under high environmental conditions during fattening period has a great adverse effect on these blood parameters. ...
Wright and Giemsa stains are Romanowsky stains used to stain peripheral blood and bone marrow smears. The most important components of these stains are oxidized methylene blue, azure B and eosin Y dyes. The eosin Y dye stains the cytoplasm of cells an orange to pink color. The methylene blue and azure B dyes stain the nucleus varying shades of blue to purple. Romanowsky stains are used to perform differential white blood cell counts and to study red blood cell morphology. Abnormal granulocyte, lymphocyte or monocyte cell counts may be used to facilitate the diagnosis of diseases such as leukemia or bacterial infections.. ...
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Results. The treatment and placebo groups were of similar gestational age (29 ± 3 vs 31 ± 3 weeks) and birth weight (1376 ± 491 vs 1404 ± 508 g), and had similar Apgar scores and 24-hour Score for Neonatal Acute Physiology scores. The mortality rate was not different between treatment and placebo groups. However, the occurrence of a subsequent nosocomial infection was lower in the rG-CSF recipients (relative risk: .19; 95% confidence interval: .05-.78). rG-CSF treatment did not alter the serum concentrations of the cytokines measured (except for G-CSF). Serum G-CSF levels and blood neutrophil counts were higher in the treatment than in the placebo group 24 hours and 48 hours after dosing. ...
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Background: Spontaneous ascitic fluid infection (SAI) is an acute infection of ascitic fluid. SAI has three subtypes; SBP, CNNA, MNB. The prototype is Spontaneous bacterial peritonitis (SBP). SBP is a frequent and serious complication in patients with cirrhosis leading to significant mortality and morbidity. Diagnosis of SBP is mainly established by elevated polymorphonuclear leukocyte count and positive ascitic fluid bacterial culture. Methodology: Records of patients with suspected diagnosis of Spontaneous ascitic fluid infection were analyzed in the present study. Patients admitted in the last one year i.e., between January 2014 to December 2014 with ascites secondary to cirrhosis were included. All patients with decompensated cirrhosis had undergone ascitic fluid paracenetesis after admission to the hospital. Ascitic fluid was centrifuged and analyzed for Total protein, Albumin, Total and Differential leukocyte count. Ascitic fluid was cultured by using BacTec method to determine the growth ...
Sweets syndrome, named after the physician who first described the condition, is also known as acute febrile neutrophillic dermatosis. The initial manifestations of this condition are non-specific and often overlooked. These include fever, elevated white blood cell count and flu-like symptoms. As the condition progresses, the patient will abruptly develop numerous tender, red or purple, plaques and papules on the arms, head, neck and trunk. Sweets syndrome is a relatively unusual but not rare dermatologic condition. It demonstrates a female prevalence; occurring about four times more commonly in women than men. The exact mechanism underlying Sweets syndrome is not known at this time. One of the current hypotheses equates the disease to the body developing a hypersensitivity reaction to an underlying infection, autoimmune disease, medication or cancer. The role of the neutrophil, which is a specialized form of white blood cell, in Sweets syndrome is thought to be an inappropriate response to ...
Advanced polycythemia vera (PV) may occur in a subset of patients with elevated hematocrit levels plus elevated white blood cell counts or disease related symptoms, despite treatment with HU at the maximum tolerated dose and phlebotomy.
Septic arthritis of the SI joint is a rare condition representing 1% to 2% of all forms of septic arthritis and bone infections. The source of infection is thought to be from hematogenous spread. The most common positive physical examination signs include maximal tenderness over the SI joint and increased pain with SI joint compression test. Patients will often have a positive straight leg raise because the sacral nerves running anterior to the SI join may be irritated. MRI is the gold standard test to diagnose an early SI joint infection. Laboratory findings typically include an elevated white blood cell count and elevated inflammatory markers (ESR and CRP), and blood cultures will often be positive for the causative bacterial agent. Identifying the responsible bacteria, if possible, helps guide the most appropriate antibiotic coverage. Obtaining an aspiration is extremely difficult due to the anatomy of the SI joint and is generally not attempted, particularly if blood cultures are positive. ...
Introduction: Foreign body ingestion is a common occurrence in both adults and in children. It is usually a benign occurrence with 75.6% of all FB ingestions passing through the GI tract spontaneously. Rarely, does the foreign body perforate the intestinal wall (0.73%). Perforation is difficult to diagnose as history, symptoms, laboratory and imaging tests are often vague and non-specific. Case Presentation: We present a case of a 55 year old Hispanic woman with a 3 day history of abdominal pain associated with anorexia, nausea and one episode of vomiting. Physical examination demonstrated tachycardia at 110 beats per minute, and an obese abdomen that was diffusely tender, with rebound tenderness in the right lower quadrant. Routine laboratory studies revealed an elevated white blood cell count and alkaline phosphatase level. CT of the abdomen demonstrated mural thickening of a small segment of small bowel. No intraperitoneal free air or fluid was seen. After 48 hours, laboratory values returned ...
TY - JOUR. T1 - Repeated dose 28-day oral toxicity study in Wistar rats with a mixture of five pesticides often found as residues in food: alphacypermethrin, bromopropylate, carbendazim, chlorpyrifos and mancozeb. AU - Jacobsen, H.. AU - Østergaard, G.. AU - Lam, Henrik Rye. AU - Poulsen, Mette Erecius. AU - Frandsen, Henrik Lauritz. AU - Ladefoged, Ole. AU - Meyer, Otto A.. PY - 2004. Y1 - 2004. N2 - Six dose groups of 8 male and female rats respectively received a daily dose equivalent to 0, 0.15, 0.006, 0.03, 0.15 or 0.3 mg/kg b.w./day chlorpyrifos (groups 1-6) and the last four dose groups (groups 3-6) received in addition daily doses equivalent to 18 mg/kg b.w./day alphacypermethrin, 30 mg/kg b.w./day bromopropylate, 45 mg/kg b.w./day carbendazim and 12.5 mg/kg b.w./day mancozeb for 28 days. Plasma acetylcholinesterase was significantly decreased in the groups 2, 5 and 6 males. Total white blood cell count was significantly lower in females of group 6. Total red blood cell count, ...
Badrick, T, Richardson, A, Lidbury, BA. 2016, Response to article: serum total bilirubin concentrations are inversely associated with total white blood cell counts in an adult population, Annals Of Clinical Biochemistry, vol. 53, no. 3, pp. 412-414. ...
In lieu of an abstract, here is a brief excerpt of the content: BOOK REVIEWS The Granulocyte: Function and Clinical Utilization. Progress in Clinical and Biological Research, vol. 13. Edited by Tibor J. Greenwalt and G. A. Jamieson. New York: Alan R. Liss, Inc., 1977. Pp. xiii+341. $30.00. For over 100 years the granulocyte has remained one of the most observed and easily recognized of human cells. Its role in the inflammatory response has long been noted, and granulocyte enumeration in the differential white cell count remains as one of the basic and most useful laboratory tests. In recent years biochemical functional rather than enumerative aspects have been increasingly studied and voluminous data accumulated. The biochemical complexities unraveled to date have led to better understanding and recognition of a variety of diseases associated with qualitative chemical defects. Progress in the blood-banking sciences has allowed for greater ease of production of the subcomponents of whole blood. ...
Total white blood cell (WBC) and neutrophil counts are lower among individuals of African descent due to the common African-derived null variant of the Duffy Antigen Receptor for Chemokines (DARC) gene. Additional common genetic polymorphisms were recently associated with total WBC and WBC sub-type levels in European and Japanese populations. No additional loci that account for WBC variability have been identified in African Americans. In order to address this, we performed a large genome-wide association study (GWAS) of total WBC and cell subtype counts in 16,388 African-American participants from 7 population-based cohorts available in the Continental Origins and Genetic Epidemiology Network. In addition to the DARC locus on chromosome 1q23, we identified two other regions (chromosomes 4q13 and 16q22) associated with WBC in African Americans (P,2.5×10(-8)). The lead SNP (rs9131) on chromosome 4q13 is located in the CXCL2 gene, which encodes a chemotactic cytokine for polymorphonuclear ...
From received questions: I am a 50 years woman complaining from backpain and weakness all the time, and have got these lab work results: Creatinine 5 mg/dl BUN 140 eGFR 9.0 mL/min/1.73m2 Haemoglobin 7.5 Total white cells count 15,000 /ml Neutrophils cells count 12,500 /ml Serum Iron 35 Please explain my results. Interpretation Creatinine is the main waste product used to measure the efficiency of the kidneys, elevated when kidney have a damage or blockage. Haemoglobin is a molecule inside red blood cells which attach oxygen and transport it to tissues. Backpain is not usually a sign of renal impairment unless.... ...
Objectives: The present study was undertaken to evaluate and highlight the importance of hematological scoring system (HSS) in the early detection of neonatal sepsis. Materials and Methods: The cross-sectional study enrolled 110 neonates who were clinically suspected of infection (study group) and normal neonates for comparison (controls), during the 1 st week of life. All peripheral blood smears were analyzed using HSS of Rodwell et al., by pathologists blinded to the infection status of the newborns. HSS assigns a score of 1 for each of seven findings significantly associated with sepsis: Abnormal total leukocyte count, abnormal total polymorphonuclear neutrophils (PMN) count, elevated immature PMN count, elevated immature: Total (I:T) PMN ratio, immature: Mature (I:M) PMN ratio ≥0.3, platelet count ≤150,000/mm 3 , and pronounced degenerative or toxic changes in PMNs. Score of ≤2 was interpreted as sepsis unlikely; score 3-4: Sepsis is possible and ≥5 sepsis or infection is very ...
Objectives: The present study was undertaken to evaluate and highlight the importance of hematological scoring system (HSS) in the early detection of neonatal sepsis. Materials and Methods: The cross-sectional study enrolled 110 neonates who were clinically suspected of infection (study group) and normal neonates for comparison (controls), during the 1 st week of life. All peripheral blood smears were analyzed using HSS of Rodwell et al., by pathologists blinded to the infection status of the newborns. HSS assigns a score of 1 for each of seven findings significantly associated with sepsis: Abnormal total leukocyte count, abnormal total polymorphonuclear neutrophils (PMN) count, elevated immature PMN count, elevated immature: Total (I:T) PMN ratio, immature: Mature (I:M) PMN ratio ≥0.3, platelet count ≤150,000/mm 3 , and pronounced degenerative or toxic changes in PMNs. Score of ≤2 was interpreted as sepsis unlikely; score 3-4: Sepsis is possible and ≥5 sepsis or infection is very ...
On examination he was thin and mildly pyrexial at 37.5°C. Scarring from his recent attack of shingles was present on the left anterior thigh in the distribution of the L2 dermatome. The oral cavity was clear. Bilaterally, shotty, non-tender lymph nodes were present in the cervical, axillary, and inguinal regions. There were no cardiovascular or respiratory abnormalities. In the abdomen he had a large, tender, irregular non-mobile right iliac fossa mass that was dull to percussion which extended from the pelvis to below the level of the umbilicus. No other masses were palpable. Neurological examination was unremarkable.. Baseline investigations showed the haemoglobin was 10.7 g/dl, total white cell count was 3.2 × 109/l, and platelet count was 122 × 109/l. The mean cell volume was low at 75 fl with a ferritin level within normal limits. The aspartate aminotransferase (AST) and albumin were abnormal at 75 IU/l (normal range 0-37 IU/l) and 29 g/l (normal range 33-47 g/l) respectively, and the ...
I was diagnosed with stage 1, grade 1 endometrial cancer in August. I had a total hysterectomy with removal of ovaries and Fallopian tubes. I was told I was cured a few weeks after the surgery and needed no chemo or radiation. Before the hysterectomy I was diagnosed with a UTI and given antibiotics. In September I noticed some blood in my urine and I felt like I had a UTI. I went to Urgent Care and a urinalysis showed elevated white blood cells and blood in the urine. I again was given antibiotics but got no relief from my symptoms. The next week I went back to Urgent Care and the doctor pulled up my urine culture results from before the hysterectomy and from the UTI she had treated me for the week before, and the results were negative. I had another UA done that day which still indicated a UTI so I was given antibiotics again. A few days later the doctor called me and said the culture was negative and to discontinue the antibiotics. She said I should see a urologist. I got in a week later with ...
Due to the fact that the child is most often exposed to helminth infection, and the study of feces for parasite eggs is not always sufficiently informative, parents are usually recommended that children with suspected disability submit a general blood test andEIA.It is they who with the greatest accuracy will help to define worms in childrens organisms. Most of all, the helminths, such as pinworms and ascarids, affect the change in the indices in this study conducted in children. They can be determined by reduced hemoglobin or elevated white blood cells. Parents should know that it is possible to take a blood test for worms from a child in a private or public laboratory. The prices for this procedure in both institutions are approximately the same and quite low. The only thing that is required is the availability of special equipment that is designed to identify various types of worms in the childs body by blood. Also, remember that the baby should not be fed for 8 hours before the test. He ...
TY - JOUR. T1 - Low blood lymphocyte count at 30 days post transplant predicts worse acute GVHD and survival but not relapse in a large retrospective cohort. AU - Gul, Z.. AU - Van Meter, E.. AU - Abidi, M.. AU - Ditah, I.. AU - Abdul-Hussein, M.. AU - Deol, A.. AU - Ayash, L.. AU - Lum, L. G.. AU - Waller, E. K.. AU - Ratanatharathorn, V.. AU - Uberti, J.. AU - Al-Kadhimi, Z.. PY - 2015/3/1. Y1 - 2015/3/1. N2 - Multiple reports have shown that low absolute lymphocyte count at day 30 (ALC30) after allogeneic hematopoietic SCT (AHSCT) is associated with higher risk of disease relapse and worse OS. However, these reports included heterogeneous populations with different grafts and GVHD prophylaxis. Therefore, we retrospectively evaluated the association of ALC30 with transplant outcomes in a cohort of 381 consecutive patients who underwent AHSCT between 2005 and 2010 and received T-replete PBSC grafts and Tacrolimus/Mycophenolate combination as GVHD prophylaxis. Median follow-up was 57 months. ...
Differential count of white blood cells (WBC) provides information on the profile of their components. There has not been done any hematological research in the alpine species Alpine Accentor (P. collaris) yet. The research found out the dependence of changes in profile of WBC count in the relation to the sex, age and year period. The most changes in the number of WBC were found in the lymphocytes and heterophils. It has been proved, that those changes are not related to sex, but are related to the age of individual. The proportion of lymphocytes was in juveniles 64% and in adults 51.9%. The proportion of heterophils was in juve-niles 33.7% and in adults 38.6%. Seasonal changes in the WBC profile were also notified. The shifts of leucocyte values were recorded during spring, summer and autumn. In the spring period the number of hetrophils decreased (32.42%) in the comparison to the autumn levels (58.43%), while in case of lymphocytes the trend was inverted (in spring 45.24%, and in autumn ...
, Human Peripheral Blood Leukocyte (Normal) tissue lysate, GTX27767, Applications: ELISA, IP, WB; ELISA, Immunoprecipitation, Western Blot (WB); CrossReactivity:
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There were no treatment-related effects on mortality. In most cases there were no effects on body weight although in one replicate experiment a decrease in weight was observed in the high dose group and body weight gain was decreased over the 2 week post-exposure. Spleen weights were increased in all gallium arsenide treated groups while thymus weights were decreased at the high dose (Table 1). A dose-response increase in lung weights occurred following treatment but none of the individual values were significant. The lungs were characterized by darkened areas consisting of lymphocyte and macrophage infiltration. There was a tendency (not significant) for a treatment-related decrease in peripheral leukocyte counts (Table 1) which was associated with a significant decrease in peripheral lymphocyte counts in the 200 mg/kg treatment group (not shown).. The immune and bone marrow studies are also summarized in Table 1. Gallium arsenide suppressed the following immune parameters dose- dependently: ...
Press Release issued Aug 8, 2017: Hematology analyzers are clinical, quantitative laboratory equipment that provide a reticulocyte analysis for in vitro diagnostic use, a leukocyte differential count, and a complete blood count. Modern equipment in the hematology analyzers market uses a combination of several methods such as light absorption, light scattering, electrical conductivity, and electrical impedance to produce complete platelet, RBC, and leukocyte analysis. The rapid developments in this truly exciting market necessitate an in-depth study which is why we have prepared the Hematology Analyzer Market: Global Industry Analysis and Forecast, 2016-2024 report.
Fig. 1. a, antiangiogenic versus conventional scheduling of cyclophosphamide for drug-resistant Lewis lung carcinoma. ▵, control saline; ○, conventional schedule [150 mg/kg every other day for three doses (white arrows, total 450 mg/kg) every 21 days]; •, antiangiogenic schedule (170 mg/kg every 6 days, CTX, thin black arrows); ▪, antiangiogenic schedule of cyclophosphamide and TNP-470 (170 mg/kg cyclophosphamide and 12.5 mg/kg TNP-470 administered on the same day of the 6-day cycle for seven cycles, CTX + TNP, thick black arrows). The inset (top right) has magnified axes for the first 21 days of therapy (n = 6 mice/group). All control and conventional schedule-treated mice died with large tumor burdens. Therapy was discontinued on the antiangiogenic schedule of cyclophosphamide alone after two of six mice died with pulmonary inflammation, accompanied by high peripheral leukocyte counts. No mouse on either schedule had visibly detectable pulmonary metastases at time of death. Therapy was ...
List of causes of Coma and Heavy periods and Low white blood cell count and Sensory symptoms, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more.
Can psoriasis cause low white blood cell count? Check out right here and right now! Read this article and find out everything about it!
Results: High statistical significance of AUDIT score in diagnosis of alcohol dependence and withdrawal complications was found(p=0.001). Majority of patients were in the age group of 31-40 years.RBC count and platelet count was found to be significantly reduced in alcohol dependence syndrome with complications(p,0.05). Total leucocyte count variation was found to be nil significant (p,0.05). High prevalence of macrocytosis (15.4%), eosinophilia (15.4%), thrombocytopenia (13.8%), lymphocytosis (10.8%) were found in alcohol dependence syndrome and higher values were observed in complications ...
Abstract: The immunostimulatory effect of the ethanolic extract of Cassia alata was tested on Swiss albino rats infected with Staphylococcus aureus by evaluating the White Blood Cells (WBC), Packed Cell Volume and total differential WBC count. The rats were in 6 groups of 2 animals per cage. The first group was given the standard inoculum but not treated. The second group was given the standard inoculum and treated with the extract. The third group was given Cassia alata ethanolic extract only while the control was given normal saline. Increase in White Blood Count (WBC) from 5000 to 7600 mm3, decrease in Packed Cell Volume (PCV) from 51 to 21% and increase in neutrophil-lymphocyte ratio indicates active infection in the infected-untreated group. In the group treated with extract there was lower White Blood Count (WBC) of 5000 and 2900 mm3 before and during infection, respectively. Decrease in neutrophil-lymphocyte ratio indicates suppression of infection/inhibition of proliferation of ...
Objective: To study determinants of incident hyperglycaemia in rural Indian mothers 6 years after delivery.. Research Design and Methods: The Pune Maternal Nutrition Study (PMNS) collected information in 6 villages near Pune on pre-pregnant characteristics, and nutrition, physical activity and glucose tolerance during pregnancy. An oral glucose tolerance test (OGTT) was repeated 6 years after delivery.. Results: Five hundred and ninety seven mothers had an OGTT at 28 weeks gestation; 3 had gestational diabetes (GDM, WHO 1999 criteria). Six years later, 42 of 509 originally normal glucose tolerant mothers were hyperglycemic (8 diabetic, 20 IGT and 14 IFG). The hyperglycemic women had shorter legs and thicker skinfolds before pregnancy (p,0.01, both) and were less active and more hyperglycemic (2-hour plasma glucose 4.8 vs. 4.4 mmol/L, p,0.001) during pregnancy. They had gained more weight during follow up (6.0 vs. 2.7 kg, p,0.001). Multivariate analysis revealed that total leucocyte count and ...
Low Eosinophils Count is also known as Eosinopenia, it occurs when the Eosinophils count is less than 50 cells/µL of human blood.. The normal white blood cell count of Eosinophils range between 450 cells/µL in infants to 200 cells/µL in adults.. Low Eosinophils count may occur due to the same causes of Leukopenia such like aplastic anemia and HIV.. Eosinophil is also reduced in the circulating blood in cases of Severe Infections, Shocks, and Adrenocortical Stimulation.. Eosinopenia is also a sing of stress and Cushings Disease since the Eosinophils are reduced due to the presence of Adrenocortical Hormones such like cortisol and aldosterone. Treatments with corticosteroids is also a cause of low Eosinophils count for the same reason.. ...
Neutrophil granulocytes: Low neutrophil (neutropenia) and high neutrophil level counts on blood tests: Easy to understand entry on this type of white blood cell (Lymphocytes B cells and T cells; Monocytes; Eosinophils; Basophils).
TY - JOUR. T1 - Relevance of Minimal Residual Disease in the Era of Targeted Agents. AU - Heltai, Silvia. AU - Ghia, Paolo. AU - Scarfò, Lydia. PY - 2019/11/1. Y1 - 2019/11/1. N2 - The evaluation of minimal residual disease (MRD) in chronic lymphocytic leukemia (CLL) has evolved in parallel with the enormous progresses in the therapeutic armamentarium and the application of cutting-edge diagnostic techniques the CLL community witnessed in the past few years. Minimal residual disease is considered an objective measure of disease status defined by the number of residual leukemic cells detected in a sample of peripheral blood and/or bone marrow as proportion of the total white blood cells and defined undetectable if fewer than 1 CLL cell among 10,000 white blood cells (10-4 or 0.01%) is detected. In this review, we aim at shedding light on how to evaluate MRD, what we already know about MRD from the experience with chemoimmunotherapy, and why MRD evaluation remains still relevant in the era of ...
BOZLU, Gulcin; TANRIVERDI, Huseyin; ASLAN, Gonul and KUYUCU, Necdet. The value of acute phase reactants and LightCycler® SeptiFast test in the diagnosis of bacterial and viral infections in pediatric patients. Arch. argent. pediatr. [online]. 2018, vol.116, n.1, pp.35-41. ISSN 0325-0075. http://dx.doi.org/10.5546/aap.2018.35.. Introduction: This study was performed to investigate the value of acute phase reactants and LightCycler® SeptiFast test to differentiate bacterial and viral infections. Population and methods: Children with fever were enrolled to this prospective study. Peripheral white blood cell (WBC), C-reactive protein (CRP) and procalcitonin (PCT) were studied from all patients on day 1, 3 and 7. Blood culture and chest X-ray were also obtained on day 1. Blood samples for LightCycler® SeptiFast test were obtained in all patients to use them if there was uncertain diagnosis between bacterial or viral infection. The patients were divided into two groups as bacterial and viral ...
Objectives: To investigate the intercourse between the platelet/lymphocyte (P/L) and neutrophil/lymphocyte ratio (N/L), and vitamin D (Vit-D) levels in low bone mineral density (BMD) of women. ...
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Six or eight months ago, I would have never believed this, says Charles L. Sawyers, M.D., a principal investigator in clinical trials for the drug STI-571. Dr. Sawyers is Director of the Prostate Cancer Program and Associate Chief for Basic Research at UCLAs Jonsson Cancer Center, and an Associate Professor in the Division of Hematology-Oncology at the UCLA School of Medicine. He spoke at the AMAs 18th Annual Science Reporters Conference, in Los Angeles, CA. Along with Brian Druker, M.D., of Oregon Health Sciences in Portland, and Moshe Talpaz, M.D., of the M.D. Anderson Cancer Center in Houston, Dr. Sawyers has been leading clinical trials of a drug currently known as STI-571. He calls the results to date amazing. Getting to the Root of the Disease STI-571 was developed to treat patients with chronic myelogenous leukemia (CML), which occurs most often among middle-aged men and women. In the chronic phase of CML, patients have a high white blood cell count, but generally symptoms are minimal ...
Monster is doing better. Went back to the vet last week,because of dehydration. High white blood count, so hes on another round of antibiotics. His kidneys are doing fine ...
The Preakness victor stands above all other Belmont competitors after his main rival was pulled due to a high white blood cell count.
Why It Occurs. A person with cancer can develop a low WBC count from the cancer or from treatment for the cancer. Cancer may be in the bone marrow, causing fewer neutrophils to be made. The WBC count can also go down when cancer is treated with chemotherapy drugs, which slow bone marrow production of healthy WBCs.. ...
scarring in the marrow), a chronically high white blood cell or platelet count, especially if they have the JAK2 ... I use, those patients should generally be treated with a stem cell transplant , if they have a donor. To prepare them for the .... Interview last updated 05/14/2015 - 1:53pm.. ...
Question - High WBC count, not sure about infection, virus or inflammation. Should I be concerned?. Ask a Doctor about diagnosis, treatment and medication for Parathyroid disease, Ask an Internal Medicine Specialist
"Cell counts". Ruemke, C. L. (1978). "The statistically expected variability in differential leukocyte counting" (PDF). In ... but 200 may be counted for better representation if the white blood cell count is high. The manual differential count produces ... Koepke, JA (1977). p. 2. Gibson, CL (1906). "The value of the differential leukocyte count in acute surgical diseases". Annals ... 12-4. Lewis, SM (1981). "Automated differential leucocyte counting: Present status and future trends". Blut. 43 (1): 1-6. doi: ...
Cite journal requires ,journal= (help) Sindik, L; Lill, A (2009). "Peripheral Blood Leukocyte Counts in Welcome Swallow ...
Peripheral eosinophilia can be seen in differential leukocyte count. Allergy testing is not definitive. At times, these tests ...
During labor, there is a rise in leukocyte count. A pregnant woman will also become hypercoagulable, leading to increased risk ... The effect of pregnancy on platelet count is unclear, with some studies demonstrating a mild decline in platelet count and ... The white blood cell count increases with occasional appearance of myelocytes or metamyelocytes in the blood. ...
"The polymorphonuclear leucocyte count in childhood haemolytic uraemic syndrome". Pediatric Nephrology. 3 (2): 130-134. doi: ... "Interleukin-8 and polymorphoneutrophil leucocyte activation in hemolytic uremic syndrome of childhood". Kidney International. ...
These males are typically immunologically superior with higher leukocyte counts. This evidence supports the idea that bright ...
TLC- (Total leucocyte count): Normal TLC in an adult person is 6000-8000 WBC/mm^3 of blood. DLC- (Differential leucocyte count ... The number of leukocytes in the blood is often an indicator of disease, and thus the white blood cell count is an important ... McBride JA, Dacie JV, Shapley R (February 1968). "The effect of splenectomy on the leucocyte count". British Journal of ... The complete blood cell count is a blood panel that includes the overall WBC count and the white blood cell differential, a ...
During treatment with pyrimethamine, leukocyte and platelet counts should be monitored weekly. Folinic acid protects against ...
"Cellular softening mediates leukocyte demargination and trafficking, thereby increasing clinical blood counts". Proceedings of ...
Laboratory studies show elevated blood leukocyte count and predominance of polymorphonuclear forms. Radiographs studies may ...
Increases in the thrombocyte number and total leukocyte and basophil count have been reported. The course of the parasitemia ...
Blood investigations including hemoglobin, total leukocyte count, platelet count, peripheral smear, red cell indices. Bone ...
Relationship of leukocyte counts in junctional epithelium, sulcus depth, and connective tissue inflammation scores". J. ... The junctional epithelium may even become infiltrated with enough leukocytes so that it resembles a microabscess. Features of ... Features of the Initial Lesion: Vasculitis of vessels subjacent to junctional epithelium Increased migration of leukocytes into ... Genetic disorders potentially associated include familial and cyclic neutropenia, Down syndrome, leukocyte adhesion deficiency ...
... including complete blood count with leukocyte differential; erythrocyte sedimentation rate; serum levels of alanine ... The following routine tests are recommended: Complete blood count Blood chemistry (electrolytes, glucose, renal function, liver ...
... differential leukocyte count) showing increased numbers of polymorphs. DLC: band cells > 20%. increased haptoglobins. micro ESR ... count 5,000-15,000/mm3 absolute band count ≤ 1,500/mm3 urine WBC count ≤ 10 per high power field (hpf) stool WBC count ≤ 5 per ... the current practice in newborns less than 30 days old is to perform a complete workup including complete blood count with ...
When the isolated BIV was inoculated into colostrum deprived young calves, they developed elevated leukocyte counts. The ... The first animal studied was an eight-year-old Holstein cow (R-29), her white blood cell count was elevated and her physical ... The cows presented with high white blood cell counts, referred to as persistent lymphocytosis (PL) which is associated with the ...
Onuf, B (1904). "Note on a Stain applicable to Differential Leucocyte Counts in the Counting Chamber". J Med Res. 12 (1): 87-93 ...
Leukocyte count. B-ALL ,30,000mm3 T-ALL ,100,000mm3. Low ... White blood cell count at diagnosis of greater than 30,000 (B- ... The higher these numbers typically points to a worse prognosis.[26] While white blood cell counts at initial presentation can ... Diagnosing ALL begins with a thorough medical history, physical examination, complete blood count, and blood smears. While many ... Laboratory tests that might show abnormalities include blood count, kidney function, electrolyte, and liver enzyme tests.[17] ...
DLC- (Differential leucocyte count): Number/ (%) of different type of leucocyte in per cubic mm. of blood. ... Counting and reference ranges. The complete blood cell count is a blood panel that includes the overall WBC count and various ... and thus the white blood cell count is an important subset of the complete blood count. The normal white cell count is usually ... A normal eosinophil count is considered to be less than 0.65×109/L.[15] Eosinophil counts are higher in newborns and vary with ...
Commonly used tests include a complete blood count (CBC), bone marrow examination, leukocyte telomere length test (e.g. Flow ... these therapies are directed to cope with effects of bone marrow failure which manifests as low red and white blood cell counts ...
... guidelines for the evaluation of blood cell analysers including those used for differential leucocyte and reticulocyte counting ... Lewis, S. M. (24 April 2009). "Standardization and harmonization of the blood count: The role of International Committee for ... Automated analyzers can speed up laboratory workflow and improve accuracy, because more cell counts and cell classification are ... The working group that developed the international guidelines for platelet count reference methods was analysed by flow ...
... making them easier to see and count. Turk's solution is intended for use in counting leukocytes in a defined volume of blood. ... Erythrocytes are hemolyzed while leukocytes are stained for easy visualization. "Türk's solution 109277". Sigma-Aldrich. ...
There was only a slight increase in mean cell hemoglobin (MCH) in terms of erythrocyte, leukocyte and platelet counts. Serum ...
A leukocyte count above 25 to 30 × 109/L is termed a leukemoid reaction, which is the reaction of a healthy bone marrow to ... Leukocytosis is a condition in which the white cell (leukocyte count) is above the normal range in the blood. It is frequently ... decreased margination of leukocytes onto vessel walls, decreased extravasation of leukocytes from the vessels into tissues, or ... and leukocytosis in which eosinophil count is elevated is eosinophilia. An extreme form of leukocytosis, in which the WBC count ...
... or leukocyte count with coronary heart disease: meta-analyses of prospective studies". JAMA. 279 (18): 1477-82. doi:10.1001/ ...
Nyquist was withdrawn from the Belmont Stakes on May 24 after developing a high leucocyte count. After being scratched from the ...
Leukocyte adhesion deficiency is diagnosed clinically and by complete blood counts that reveal leukocytosis with neutrophilia. ... "Two mutations in the KINDLIN3 gene of a new leukocyte adhesion deficiency III patient reveal distinct effects on leukocyte ... FERMT3 deficiency on β(2) integrin function depend on both cell type (Natural killer cell or Leukocytes) and the integrin ... FERMT3 mutations can result in autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). a deficiency in beta1 ...
... levels are positively correlated with pro-inflammatory biomarkers, such as tumor necrosis factor-α, leukocyte counts, and ...
The erythrocyte count is high at birth and increases till the age of 2-3 months, while in contrast, the leucocyte count is low ... The neutrophil count is high at all ages. The haematocrit and haemoglobin content decreases till 20-30 days after birth. A peak ...
... for human leukocyte antigen (HLA) matching (see PGD for HLA matching) in order to donate to an ill sibling requiring HSCT. ... expansion of HSC and their progeny is sufficient to normalize the blood cell counts and re-initiate the immune system. The ... the donor should preferably have the same human leukocyte antigens (HLA) as the recipient. About 25 to 30 percent of allogeneic ...
Langerhans cells - LAS - lentivirus - lesion - leukocytes - leukocytosis - leukopenia - leukoplakia - LFT - LIP - lipid - ... complete blood count (CBC) - computed tomography scan (C-T scan) - concomitant drugs - condyloma - condyloma acuminatum - ... human leukocyte antigens (HLA) - human papilloma virus (HPV) - human T cell lymphotropic virus type I (HTLV-I) - human T cell ...
... neutropenia/myelodysplasia P14 deficiency Leukocyte adhesion deficiency type 1 Leukocyte adhesion deficiency type 2 Leukocyte ... The basic tests performed when an immunodeficiency is suspected should include a full blood count (including accurate ... lymphocyte and granulocyte counts) and immunoglobulin levels (the three most important types of antibodies: IgG, IgA and IgM). ...
... and decreases the incidence of abnormally low white blood cell counts by one-third.[8] However, pulsed intravenous ... and human leukocyte antigen genes may influence the risk of developing GPA.[7] ... Due to a high frequency of abnormally low white blood cell counts seen with cyclophosphamide treatment, Pneumocystis jirovecii ...
... leukocytes), or leukocyte esterase.[42] Another test, urine microscopy, looks for the presence of red blood cells, white blood ... Urine culture is deemed positive if it shows a bacterial colony count of greater than or equal to 103 colony-forming units per ... and an increased white blood cell count.[21] ...
... and Cladosporium with indoor spore counts ranging from 6,142 - 735,123 spores m−3.[16] Molds isolated following flooding were ... and granulocyte-macrophage colony-stimulating factor for priming leukocyte-mediated hyphal damage of opportunistic fungal ...
The leukocyte alkaline phosphatase (LAP) score, which refers to the amount of alkaline phosphatase per neutrophil, will ... Nervousness will very slightly raise the neutrophil count because of this effect.[citation needed] A neutrophilia might also be ... Primary neutrophilia can additionally be a result of Leukocyte adhesion deficiency. A "left shift" refers to the presence of ... Granulocytosis (often used as synonym) Neutropenia (having too few neutrophils) Absolute neutrophil count "neutrophilia" at ...
However, YCM is also known to be present in a significant number of men with reduced fertility or reduced sperm count.[citation ... Schröder J, Thlikainen A, de la Chapelle A (1974). "Fetal leukocytes in the maternal circulation after delivery: Cytological ... The following are some of the gene count estimates of human Y chromosome. Because researchers use different approaches to ...
"Journal of Leukocyte Biology. 99 (5): 699-710. doi:10.1189/jlb.2a0215-050rr. PMC 5404712. PMID 26590149.. ... For severely low platelet counts, patients may require platelet transfusions or removal of the spleen. For patients with ... low platelet count), immune deficiency, and bloody diarrhea (secondary to the thrombocytopenia).[1] It is also sometimes called ... resulting from a low platelet count (i.e. thrombocytopenia). Spontaneous nose bleeds and bloody diarrhea are also common and ...
HIV infection in association with a last known CD4 count of ,50/mm3 ... by blocking leukocyte adhesion to selectins, and by limiting the thrombin-induced inflammatory responses within the ...
They may feel relatively well, with a low CRP and white cell count, despite extensive bacterial load". www.rcpe.ac.uk, S. 153 ... https://www.ncbi.nlm.nih.gov/books/NBK99496/ "Female carriers of X-linked CGD(who have two populations of leukocytes). ...
Peripheral eosinophilia can be seen in differential leukocyte count. Allergy testing can either show allergies that are not ...
These include a RBC count (the number of red blood cells per volume of blood), calculation of the hematocrit (percentage of ... From left to right: human red blood cell, thrombocyte (platelet), leukocyte.. Human. ... Anemias (or anaemias) are diseases characterized by low oxygen transport capacity of the blood, because of low red cell count ... balancing the total circulating red blood cell count. Eryptosis is increased in a wide variety of diseases including sepsis, ...
... of the total CSF leukocyte (white blood cell) count.[36] The chemical analysis of the CSF typically resembles the findings in " ...
In common parlance, the term polymorphonuclear leukocyte often refers specifically to "neutrophil granulocytes",[2] the most ... Gleich, Gerald J.; Adolphson, Cheryl R. (1986). "The Eosinophilic Leukocyte: Structure and Function". Advances in Immunology ... Injured basophils and other leukocytes will release another substance called prostaglandins that contributes to an increased ... They are also called polymorphonuclear leukocytes (PMN, PML, or PMNL) because of the varying shapes of the nucleus, which is ...
"The Numbers Count", National Institute of Mental Health. Accessed 28 May 2007. ... "Internalizing disorders and leukocyte telomere erosion: a prospective study of depression, generalized anxiety disorder and ...
thrombocytopenia: platelet count , 150×109/L.. Treatment[edit]. Treatment is done to address the underlying cause. Blood ... The T cell activated macrophages engulf erythrocytes, leukocytes, platelets, as well as their progenitor cells. Along with ... If only two parameters from the complete blood count are low, the term bicytopenia can be used. The diagnostic approach is the ... leukopenia: total white cell count , 4.0 x 109/L. Decrease in all types of white blood cells (revealed by doing a differential ...
"Medical Encyclopedia: RBC count". Medline Plus. Retrieved 18 November 2007.. Unknown parameter ,dateformat=. ignored (મદદ); ... "Leukocyte functions and percentage breakdown". Molecular Biology of the Cell. NCBI Bookshelf. Retrieved 2007-04-14.. Check ...
On March 22, 2013 Kim de Gelder was found guilty of four counts of murder and was sentenced to life imprisonment. ... leukocyte) imaging, thyroid imaging or bone scintigraphy. ...
Marshall JC (March 2008). "Sepsis: Rethinking the approach to clinical research". Journal of Leukocyte Biology. 83 (3): 471-82 ... However, platelet transfusion is suggested for platelet counts below (10 × 109/L) without any risk of bleeding, or (20 × 109/L ... platelet count , 80,000/mm3 or 50% drop from maximum in chronically thrombocytopenic, or ... An uncontrolled immune response is then activated because leukocytes are not recruited to the specific site of infection, but ...
... stimulate leukocyte phagocytosis of bacteria, and reduce the production of pro-inflammatory cytokines by leukocytes. In animal ... In this count, carbon then has only two valence electrons in the molecule compared to four in the free atom. ... It is calculated by counting all the bonding electrons as belonging to the more electronegative oxygen. Only the two non- ... carbon monoxide has been shown to inhibit the movement of leukocytes to inflamed tissues, ...
Gallia, Gary L.; Tamargo, Rafael J. (1 October 2006). "Leukocyte-endothelial cell interactions in chronic vasospasm after ... the CSF is evaluated for RBC count, and presence or absence of xanthochromia.[18] ...
... by full blood count and iron studies), folic acid and vitamin B12 deficiency and hypocalcaemia (low calcium levels, often due ... also called the human leukocyte antigen) system and distinguishes cells between self and non-self for the purposes of the ...
This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria[6] ... Following a reduction in pathogen count, many pathogen-specific Tregs are present that, now without a TLR2 signal, become ... TLR2 is expressed on microglia, Schwann cells, monocytes, macrophages, dendritic cells, polymorphonuclear leukocytes (PMNs or ...
... leukocytes express surface variable lymphocyte receptors (VLRs) generated from somatic recombination of leucine-rich ... which excludes the nostrils from the count. In British folklore, the monster known as the Lambton Worm may have been based on a ...
Complete blood count[edit]. Main article: Complete blood count. A complete blood count (CBC) is a test panel requested by a ... Leukocytes are found throughout the body, including the blood and lymphatic system. There are a variety of types of white ... Abnormally high or low counts may indicate the presence of many forms of disease, and hence blood counts are amongst the most ... In the past, counting the cells in a patient's blood was performed manually, by viewing a slide prepared with a sample of the ...
Complete blood count. *Cytotoxicity. *Human leukocyte antigen. *Innate lymphoid cell. *Lymphoproliferative disorders ...
Leukocyte count synonyms, Leukocyte count pronunciation, Leukocyte count translation, English dictionary definition of ... Leukocyte count. n. Abbr. WBC Any of various cells that in adult mammals are produced in bone marrow, have a nucleus but no ... Leukocyte count - definition of Leukocyte count by The Free Dictionary https://www.thefreedictionary.com/Leukocyte+count ... The investigations included estimation of haemoglobin, differential count, total leukocyte count, platelet count, fasting blood ...
Comparison of leukocyte counts in sputum, bronchial biopsies, and bronchoalveolar lavage.. Maestrelli P1, Saetta M, Di Stefano ... Differential counts of leukocytes were performed on cytospin preparations of sputum and BAL. Eosinophils, macrophages, ... we counted the number of leukocytes in sputum, BAL, and bronchial biopsies obtained from subjects with asthma and with chronic ... However, there was a fairly good agreement between the number of eosinophils counted with the three techniques in asthmatics ...
ETDEWEB / Search Results / Decline of blood leukocyte counts 1947-59, Hiroshima and Nagasaki ... Ichimaru, Michito, Ueda, Shoichi, and Blaisdell, R K. Decline of blood leukocyte counts 1947-59, Hiroshima and Nagasaki. Japan ... Earlier reports of progressive decline in leukocyte counts in Hiroshima from about 1948 to 1954 have been confirmed. A similar ... Ichimaru, Michito, Ueda, Shoichi, & Blaisdell, R K. Decline of blood leukocyte counts 1947-59, Hiroshima and Nagasaki. Japan. ...
Erythrocyte Count · Female · Glucans · Hordeum · Leukocyte Count · Male · Nervous System Diseases · Organ Size · Rats · Rats, ... Erythrocyte Count · Erythrocyte Indices · Female · Isomaltose · Leukocyte Count · Male · Organ Size · Rats · Rats, Wistar · ... erythrocyte count · feeding behavior · glucosuria · growth · histology · kidney · kidney calcification · leukocyte count · ... leukocyte count · lifestyle · lipoprotein blood level · lymphocyte count · male · mean corpuscular hemoglobin · mean ...
What is leukocyte count, differential? Meaning of leukocyte count, differential as a legal term. What does leukocyte count, ... Definition of leukocyte count, differential in the Legal Dictionary - by Free online English dictionary and encyclopedia. ... redirected from leukocyte count, differential). Also found in: Dictionary, Thesaurus, Medical, Financial, Encyclopedia. Count. ... Index, h.t. In real actions, the declaration is most usually called a count. Steph. Pl. 36, See Common count; Money count. ...
... De Gruyter , Published ... Article Automated analysis of pleural fluid total and differential leukocyte counts with the Sysmex XE-2100 Robert de Jonge, ... "Automated analysis of pleural fluid total and differential leukocyte counts with the Sysmex XE-2100" Clinical Chemistry and ... "Automated analysis of pleural fluid total and differential leukocyte counts with the Sysmex XE-2100" Clinical Chemistry and ...
glossary:leukocyte_count. Leukocyte Count:. A count of the number of white blood cells per unit volume in venous blood. A ... glossary/leukocyte_count.txt · Last modified: 2012/10/16 14:40 (external edit) ... differential leukocyte count measures the relative numbers of the different types of white cells. ...
... of the sample had abnormal leukocyte counts: low WBC counts 15 (5.2%) and high 116 (40%). High WBC counts were associated with ... The aim of this study was to estimate the prevalence of abnormal leukocyte count (either low or high) and identify factors ... Male gender, cough, low hemoglobin, and low heart rate were associated with high WBC count. Strategies targeting high WBC count ... Abnormal leukocyte count was common: approximately five in ten Saudi SCD patients assessed in this sample. ...
TOTAL LEUKOCYTE COUNTS IN HUMAN BLOOD DURING PREGNANCY(TOTAL LEUKOCYTE COUNTS IN HUMAN BLOOD DURING PREGNANCY*) J. B. CAREY, M. ... TOTAL LEUKOCYTE COUNTS IN HUMAN BLOOD DURING PREGNANCY(TOTAL LEUKOCYTE COUNTS IN HUMAN BLOOD DURING PREGNANCY*). Ann Intern Med ...
We studied the prognostic value of the third-day dialysis effluent leukocyte count after antibiotic ... For each episode of peritonitis, the leukocyte count of the effluent was measured on the third day after initiation of empiric ... Peritonitis was defined by fever, abdominal pain, and cloudy effluent with a leukocyte count greater than 100/mm3 or a positive ... We studied the prognostic value of the third-day dialysis effluent leukocyte count after antibiotic therapy for prediction of ...
What is leukocyte count, differential? Meaning of leukocyte count, differential as a finance term. What does leukocyte count, ... Definition of leukocyte count, differential in the Financial Dictionary - by Free online English dictionary and encyclopedia. ... redirected from leukocyte count, differential). Also found in: Dictionary, Thesaurus, Medical, Legal, Encyclopedia. Count. On a ... Leukocyte count, differential financial definition of leukocyte count, differential https://financial-dictionary. ...
Complete blood cell counts, differential leukocyte counts, and hemoglobin and hematocrit determinations were performed on ... cell count significantly (Figure 1). Counts had returned to baseline by 3 hours after the prolonged exercise, but again, counts ... Leukocyte Counts. All three types of exercise provoked leukocytosis that persisted for 3 hours after exercise. The magnitude of ... MAIN MEASUREMENTS: Blood samples were analyzed for total leukocyte counts, total T cells, T helper/inducer cells, T suppressor/ ...
Results. In univariable analysis C3, CRP and leukocyte count, but not ESR, were significantly correlated with HOMA index. In ... Serum C3 is a stronger inflammatory marker of insulin resistance than C-reactive protein, leukocyte count and erythrocyte ... Serum C3 is a stronger inflammatory marker of insulin resistance than C-reactive protein, leukocyte count and erythrocyte ... Serum C3 is a stronger inflammatory marker of insulin resistance than C-reactive protein, leukocyte count and erythrocyte ...
The Role of Polymorphonuclear Leukocyte Counts from Urethra, Cervix, and Vaginal Wet Mount in Diagnosis of Nongonococcal Lower ... A count of WBCs per microscopic field in a stained vaginal smear or vaginal wet mount may be used. However, the thickness and ... Objective. The aim of this study was to evaluate whether the polymorphonuclear leukocyte (PMNL) inflammatory response in women ... Association between Leukocyte Concentration and Levels of Immune Mediators," American Journal of Reproductive Immunology, vol. ...
THE LEUKOCYTE COUNT IN PRIMARY ATYPICAL PNEUMONIA OF UNDETERMINED ETIOLOGY* OVID O. MEYER, F.A.C.P.; ETHEL W. THEWLIS ... Association Between Eosinophilic Leukocyte Count and Hematoma Expansion in Acute Spontaneous Intracerebral Hemorrhage. ... THE LEUKOCYTE COUNT IN PRIMARY ATYPICAL PNEUMONIA OF UNDETERMINED ETIOLOGY*. Ann Intern Med. 1944;21:977-982. doi: https://doi. ... Treatment of Fever in Hospitalized Patients with Low White Blood Cell Counts Annals of Internal Medicine; 137 (2): I-20 ...
"Leukocyte Count" by people in this website by year, and whether "Leukocyte Count" was a major or minor topic of these ... "Leukocyte Count" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... A differential leukocyte count measures the relative numbers of the different types of white cells. ... Below are the most recent publications written about "Leukocyte Count" by people in Profiles. ...
Effect of somatic cell count and polymorphonuclear leucocyte content of milk on composition and proteolysis during ripening of ... Effect of somatic cell count and polymorphonuclear leucocyte content of milk on composition and proteolysis during ripening of ... Identification of peptides in milk as a result of proteolysis at different levels of somatic cell counts using LC MALDI MS/MS ... Correlation between mastitis occurrence and the count of microorganisms in bulk raw milk of bovine dairy herds in four ...
Pre and post exercise variances in differential leukocyte count revealed strong correlations between neutrophil and sympathetic ... differential leukocyte count and blood lactate level before and after short, maximal exercise to explore methods of quantifying ... The results of the study demonstrated significant alterations in autonomic parameters and differential white blood cell count ... Suzuki, K., Saoto, H. and Endo, T. (1995) Variation of neutrophil active oxygen and differential count of leukocytes during ...
Some Effects of X-irradiation on the Plasma Corticosterone, Adrenal Weights, and Differential Leukocyte Count in the Rat ... Gaugl, John F. Some Effects of X-irradiation on the Plasma Corticosterone, Adrenal Weights, and Differential Leukocyte Count in ...
The median leukocyte counts in arbovirus infection episodes were 3.19 × 109/L and leucopenia (, 4 × 109 leukocytes/L) yielded a ... Initial platelet and leukocyte counts might be useful for the clinical differential diagnosis of fever in the returning ... Platelet and leukocyte counts were not significantly altered in episodes caused by diarrhea and other gastrointestinal symptoms ... The aim of this study was to establish the effectiveness of platelet and leukocyte counts in the differential diagnosis of ...
... for cytometry leukocyte counts (P , 0.001 compared to red blood cell and bacterial counts). ... for RBC counts and 0.89 (95% CI, 0.87 to 0.92) for bacterial counts. The overall diagnostic performance of urinary WBC counts ... a and b) Modeling of the positive and negative predictive values (PPV and NPV, respectively) of cytometry leukocyte counts with ... Accuracy of Automated Flow Cytometry-Based Leukocyte Counts To Rule Out Urinary Tract Infection in Febrile Children: a ...
He had absence of splenomegaly and marked periodic fluctuations of leucocyte counts, occurring spontaneously, in the initial ...
Reduction of Leukocyte Counts by Hydroxyurea Improves Cardiac Function in Rats with Acute Myocardial Infarction - Add Comment # ...
Perioperative leukocyte count MeSH Terms expand_less. expand_more. Anesthesia Demography Drainage Fever Hospitalization Humans ... No significance differences were found between the two groups with regard to the perioperative leukocyte counts. CONCLUSION: ... Assessment of Peritoneal Irrigation and Drainage by Perioperative Leukocyte Count following Gastric Cancer Surgery. ... perioperative leukocyte counts and operative complications were retrospectively analyzed in these consecutive patients. RESULTS ...
Automaton for Cell Count and Physical Five-Part Leukocyte Differentiation ... A New Development in Haematological Cell Counting: The Sysmex NE-8000, ...
Effects of electro-acupuncture on T cell populations, NK activity, humoral immunity and leukocyte count in patients undergoing ... Effects of electro-acupuncture on T cell populations, NK activity, humoral immunity and leukocyte count in patients undergoing ...
We studied the role of preoperative leukocyte count and C-reactive ... Leukocyte Count*. Predictive Value of Tests. Preoperative Care. Retrospective Studies. Sensitivity and Specificity. ... A fertile-aged woman with right lower abdominal pain but unelevated leukocyte count and C-reactive protein. Acute appendicitis ... In particular, what is the clinical value of unelevated leukocyte count and CRP in excluding acute appendicitis in these ...
The leukocyte counts, along with the counts of each different leukocyte (e.g., basophil, neutrophil, eosinophil, lymphocyte and ... had changes in leukocyte counts, including higher ratios of neutrophil-to-lymphocytes (N/L ratio). Leukocyte counts were ... Antarctica Crabeater seal Health status Leopard seal Leukocyte counts Weddell seal This is a preview of subscription content, ... DAmico VL, Bertellotti M, Benzal J, Coria N, Vidal V, Díaz JI, Barbosa A (2016a) a) Leukocyte counts in different populations ...
Postoperative morbidity and mortality in relation to leukocyte counts and time to surgery after short-course preoperative ... Preoperative leukocyte counts did not influence postoperative morbidity, but a poor response on day 1 increased the risk of ... Impaired postoperative leukocyte reaction after preoperative short-course radiotherapy has been reported. The aim was to assess ... CONCLUSIONS: Impaired postoperative leukocyte reaction is frequent after short-course radiotherapy and increases the risk of ...
... differential leucocyte count in cats. Lab test paper including overview, sampling, tests, result data and more. All information ... Relative leucocyte numbers are established by manual or machine counting the number of the different leucocyte types as a ... Hematology: differential leucocyte count Synonym(s): White cell count, WBC count. Contributor(s): Karen L Gerber ...
  • 2-6 Although laboratory markers of infection might aid in differentiating the type of infection in infants and children, opinions vary on the interpretation of tests such as the leucocyte count, neutrophil count, band cell count, and C reactive protein concentration. (bmj.com)
  • The patient's neutrophil count, however, is low (30), and when this is multiplied by the white cell count (6, 000 x 30 1, 800 neutrophilsul), the result is a low absolute number. (bitsosob.gq)
  • Jan 14, 2015 Differential blood count is also used along with leukocyte count (WBC) to generate an absolute value for each type of white blood cells (eg, absolute neutrophil count, absolute lymphocyte count, or absolute eosinophil count), which usually gives more meaningful information than the percentage of each, since relative percentage can be misleading. (bitsosob.gq)
  • In addition, the enhancements of chemiluminescence were positively correlated with the increase in segmented neutrophil count. (bisp-surf.de)
  • Effects of exhaustive endurance exercise and its one-week daily repetition on neutrophil count and functional status in untrained men by: Suzuki, K., et al. (bisp-surf.de)
  • Association of neutrophil count with microembolization in patients with symptomatic carotid artery stenosis. (lenus.ie)
  • Absolute neutrophil count and neutrophil/lymphocyte ratio were also higher in patients, though without statistical significance. (openbiochemistryjournal.com)
  • The parameters that were statistically significant related with adiposity markers were neutrophil count and CRP levels. (openbiochemistryjournal.com)
  • The neutrophil count was positively and statistically correlated with body mass index (BMI), BMI z-score, waist circumference and waist/height ratio, and also with CRP levels. (openbiochemistryjournal.com)
  • When performing multiple regression without CRP, the only variable that remained statistically associated with neutrophil count was BMI. (openbiochemistryjournal.com)
  • our results demonstrated in obese patients aged 6-12 years, a significant change in the differential leukocyte count towards neutrophilia, together with a significant higher CRP concentration, and that absolute neutrophil count correlates with obesity markers and with CRP levels. (openbiochemistryjournal.com)
  • Our data also indicate that neutrophil count, a current clinically used low-cost parameter, may be used as an obesity-related inflammatory marker in young obese patients. (openbiochemistryjournal.com)
  • Absolute counts of peripheral blood leukocyte subpopulations i. (mysciencework.com)
  • Absolute counts of peripheral blood leukocyte subpopulations in intraabdominal sepsis and pneumonia-derived sepsis: a pilot study. (mysciencework.com)
  • Differential peripheral blood leukocyte counts and respiratory symptoms, airway reactivity, & lung function. (ox.ac.uk)
  • Differential leukocyte count (Diff) - peripheral blood. (medlineplus.gov)
  • The dosage and intensity of therapy are based on surrogate markers such as peripheral blood leukocyte and neutrophil counts. (jyu.fi)
  • C-reactive protein level and leukocyte count have also been highlighted as independent risk markers of CVD. (elsevier.com)
  • The association between leukocyte count and subsequent risk of major coronary heart disease events was examined using data from three prospective cohort studies- two from the United States and one from Great Britain. (elsevier.com)
  • In this study we investigated the association between leukocyte count and incident SAH in a large prospective cohort study from an urban population. (beds.ac.uk)
  • METHODS: We calculated the mean leukocyte count and CRP values in (1) 100 consecutive fertile-aged women operated on for a clinical suspicion of acute appendicitis but with an uninflamed appendix found at appendectomy, and (2) 100 consecutive fertile-aged women operated on for a clinical suspicion of acute appendicitis and acute appendicitis found at appendectomy. (biomedsearch.com)
  • Median CRP level and mean leukocyte count increased in accordance with serum ALP quartiles. (elsevier.com)
  • The leukocyte counts, along with the counts of each different leukocyte (e.g., basophil, neutrophil, eosinophil, lymphocyte and monocyte), were made from blood smears viewed under the light microscope. (springer.com)
  • Basophil, eosinophil, and lymphocyte counts were higher in the leopard seal, while the N/L ratio, as well as the neutrophil counts, were higher for the crabeater seal. (springer.com)
  • Changes in calcium, phosphorus, protein, albumin, and liver enzyme levels were not significant.The results indicate that methylphenidate may cause hypokalemia and elevated glucose, leukocyte, neutrophil, lymphocyte and eosinophil counts. (eunetworkadultadhd.com)
  • As a potential stress indicator, we examined whether seals with lice, so presumably under greater physiological stress, had changes in leukocyte counts, including higher ratios of neutrophil-to-lymphocytes (N/L ratio). (springer.com)
  • Lymphocyte transformation and changes in leukocyte count: effects of anesthesia and operation. (semanticscholar.org)
  • 6 g/dL, total leukocyte count 20,300/dL, platelet count 392,000/dL, erythrocyte sedimentation rate (ESR) 84 mm in first hour, and C-reactive-protein 128 mg/L. (thefreedictionary.com)
  • These factors include the progression of cancer, tumour location (genital), anemia, a high platelet count, a high leukocyte count (450 x 10[sup. (thefreedictionary.com)
  • Automated Hemoglobin, Hematocrit, RBC, WBC, and Platelet Count and Automated Differential WBC Count: : Complete Blood differential leukocyte count significance A differential can also detect immature white blood cells and abnormalities, both of which are signs of potential issues. (bitsosob.gq)
  • Increased platelet count and leucocyte-platelet complex formation in acute symptomatic compared with asymptomatic severe carotid stenosis. (lenus.ie)
  • The mean hemoglobin was higher in patients with normal WBC counts ( P =0.024), while the mean hemoglobin S was high in patients with high WBC counts ( P =0.003). (dovepress.com)
  • After adjustment for potential confounders, predictors of high WBC counts were male gender (adjusted odds ratio [aOR]=3.63) and patients with cough (aOR=2.18), low hemoglobin (aOR=0.76), and low heart rate (aOR=0.97). (dovepress.com)
  • Male gender, cough, low hemoglobin, and low heart rate were associated with high WBC count. (dovepress.com)
  • MEASUREMENTS: Hemoglobin, leukocytes, and thrombocytes were measured for all subjects with and without familial longevity. (isharonline.org)
  • Other related health indicators of our body are hemoglobin and RBC counts. (buddymd.com)
  • Therefore, we investigated the effects of CAJ supplementation primarily on leukocyte counts and secondary on oxidative stress and cortisol changes after high-intensity exercise in trained and untrained men. (biomedcentral.com)
  • However, the chronic effect of CAJ ingestion on the exercise-induced leukocyte counts, oxidative stress and circulating cortisol in trained and untrained populations remain unknown. (biomedcentral.com)
  • Therefore, we investigated the chronic effects of CAJ supplementation on primarily on leukocyte counts and secondary on oxidative stress and cortisol changes in both endurance-trained and sedentary subjects before, and after, a bout of high-intensity, endurance exercise. (biomedcentral.com)
  • For the first time, we investigated the relationship between postprandial dysmetabolism and the Peroxidation of Leukocytes Index Ratio (PLIR), a test that measures the resistance of leukocytes to exogenous oxidative stress and their functional capacity of oxidative burst upon activation. (hindawi.com)
  • In this pilot study, we aimed to investigate the relationship between the improvement of postprandial dysmetabolism by a functional cookie, covered by dark chocolate and containing glucomannan, inulin, FOS, and Bacillus coagulans strain GanedenBC30 [ 15 ], and the Peroxidation of Leukocytes Index Ratio (PLIR), a test that measures the resistance of leukocytes to exogenous oxidative stress and their functional capacity of oxidative burst upon activation [ 16 ]. (hindawi.com)
  • The following cell populations were examined: white blood cell count (WBC), monocytes, lymphocytes:CD3⁺, CD4⁺ and CD8⁺ T cells, B cells, and NK cells. (mysciencework.com)
  • The other two leukocyte categories, lymphocytes and monocytes, belong to the mononuclear cell group. (biomedcentral.com)
  • The test, which is usually ordered as part of a complete blood count (CBC), measures the amounts of the five normal white blood cell types - neutrophils, lymphocytes, monocytes, eosinophils and basophils - as well as abnormal cell types if they are present. (wikipedia.org)
  • To determine the relationship between inflammatory cells in sputum, bronchoalveolar lavage (BAL), and bronchial mucosa, we counted the number of leukocytes in sputum, BAL, and bronchial biopsies obtained from subjects with asthma and with chronic bronchitis in stable condition or during exacerbations. (nih.gov)
  • In order to explore whether some form of strenuous exercise might provide an useful model for the inflammatory process, we studied the effects of three different exercise protocols on blood leukocyte count during and following exercise. (scielo.br)
  • Serum C3 is a stronger inflammatory marker of insulin resistance than C-reactive protein, leukocyte count and erythrocyte sedimentation rate. (diabetesjournals.org)
  • The aim of this study was to evaluate whether the polymorphonuclear leukocyte (PMNL) inflammatory response in women with nongonococcal lower genital tract infection (LGTI) can be used to optimize criteria for syndromic treatment. (hindawi.com)
  • The aim of the present study is to investigate systemic levels of inflammatory markers of cardiovascular diseases like C-reactive protein (CRP), interleukin-6 (IL-6), total leukocyte count and differential count in patients with chronic periodontitis, in comparison to healthy individuals without periodontal disease. (uwi.edu)
  • Background: Atherosclerosis is an inflammatory disease, and leukocyte levels are associated with future risk of ischemic cardiac disease. (elsevier.com)
  • For that purpose, several rapid urinary tests are commonly used, including dipstick biochemical analysis of urine for nitrites or leukocyte esterase (LE), and microscopic examination of urine for formed elements, including white blood cells (WBCs) and bacteria ( 4 ). (asm.org)
  • And several studies for new markers such as procalcitonin and leukocyte esterase have been conducted recently [ 4 , 7 ]. (chikd.org)
  • The investigators intend to compare the characteristics of platelets, monocytes and neutrophil data of volume, scatter and conductivity obtained from routine blood count level with flow cytometry results defining platelet leukocyte aggregates. (clinicaltrials.gov)
  • Higher than the normal leukocyte count indicates an infection or inflammation being treated by the body. (1mg.com)
  • Lower than the normal leukocyte count indicates improper functioning of the immune system. (1mg.com)
  • In conclusion, the determination of urinary WBC counts by flow cytometry provides optimal performance as an initial diagnostic test for UTI in febrile children. (asm.org)
  • CONCLUSION: Although clinical symptoms and signs indicated acute appendicitis, unelevated leukocyte count and CRP values excluded it, with a 100% predictive value in the current study of fertile-aged women. (biomedsearch.com)
  • CONCLUSION In critically ill children the admission procalcitonin concentration is a better diagnostic marker of infection than C reactive protein or leucocyte count. (bmj.com)
  • Conclusion: A lower admission leukocyte count independently predicts good and excellent outcomes at 3 months in AIS patients undergoing rt-PA treatment. (current-neurovascular-research.com)
  • Conclusion: Relative elevations in leukocyte count are independently associated with an increased risk of future ischemic stroke and other cardiovascular events. (elsevier.com)
  • The premise is that through blood counts (no need for specialized flow cytometry) and through the parameters mentioned a conclusion can be reached about platelet leukocyte aggregates. (clinicaltrials.gov)
  • Multivariable logistic regression revealed admission leukocyte count as an independent predictor of good and excellent outcomes at 3 months. (current-neurovascular-research.com)
  • Serum ALP quartiles were categorized as follows: Q1: ≤51, Q2: 52-61, Q3: 62-74 and Q4: ≥75 U/L. The odds ratios (ORs) and 95% confidence intervals (CIs) for high CRP and leukocyte count (≥75th percentiles) were calculated after adjusting for confounding variables across serum ALP quartiles using multiple logistic regression analysis. (elsevier.com)
  • The odds ratios (ORs) and 95% confidence intervals (CIs) for high leukocyte count (≥ 75th percentile) were calculated across GGT quartiles using multiple logistic regression analyses. (yonsei.ac.kr)
  • Lung tissue polymorphonuclear leukocyte (PMN) counts (expressed as PMNs/field) in 10 different fields, excluding airways and pulmonary vessels under 400 × magnification in non-dependent and dependent lung regions of the control and isoflurane groups. (nih.gov)
  • Periodontitis results in higher systemic levels of CRP, IL-6, total leukocyte count and neutrophils. (uwi.edu)
  • Blood samples were analyzed for total leukocyte counts, total T cells, T helper/inducer cells, T suppressor/cytotoxic cells, B cells, cytolytic T cells, and natural killer cells. (scielo.br)
  • This graph shows the total number of publications written about "Leukocyte Count" by people in this website by year, and whether "Leukocyte Count" was a major or minor topic of these publications. (umassmed.edu)
  • Total leukocyte count and differential count were estimated by standard clinical laboratory method. (uwi.edu)
  • Total leukocyte count was also elevated in Group III (10.4 x 103/c.mm) compared to Group II and Group I (9.2 x 103/c.mm and 7.9 x 103/c.mm). (uwi.edu)
  • Relative leucocyte numbers are established by manual or machine counting the number of the different leucocyte types as a percentage of the total. (vetstream.com)
  • Semen examination showed total count 62 million/ml and pus cells 2-3/hpf. (healthcaremagic.com)
  • present Total sperm count . (healthcaremagic.com)
  • It is concluded that a total white count and PMN percentage are of no use in predicting the type of infection. (nus.edu.sg)
  • Aims The aim of this study was to correlate total and differential leucocyte (WBC) count with myocardial blush, peak CK levels, and left ventricular (LV) functional recovery at 6 months in 238 consecutive acute myocardial infarction (MI) patients treated with successful primary coronary angioplasty (PCI). (bitsosob.gq)
  • While WBC count indicates an increase or decrease in total white cell numbers, the WBC Differential Count reports the proportion of each subtype of WBC, as a percentage of total WBC present. (bitsosob.gq)
  • Sep 15, 2015 The total white blood cell count is expressed as an absolute number and is further divided into subtypes of white blood cells by a differential WBC count, which is expressed as a percentage and absolute number. (bitsosob.gq)
  • Differential Leukocyte Count Test measures the total number of all the WBCs in blood. (1mg.com)
  • Leukocyte Differential Counting application generating alerts for every 100 cells counted by adding erythroblasts out of the total count. (shouthindi.com)
  • estimation of total leukocyte count (TLC). (medstudentscorner.com)
  • There should not be a difference of 15 cells in four corner square counting in highest and lowest total number of cells. (medstudentscorner.com)
  • Total WBC count is enormously increased. (indianmedicinalplants.info)
  • You know from one of our previous articles that white blood cell count or total leukocyte count is a test which we perform to get the count of white blood cells in our blood. (allmedtests.com)
  • The total 100 leukocytes are studied, identified and recorded from a blood smear. (medstudentscorner.com)
  • Total Leukocyte Count Test measures the total amount of all the leukocytes in blood. (1mg.com)
  • During this time, the total leukocyte count remains high in blood. (1mg.com)
  • We observed no differences in neutrophil, monocyte, or total leucocyte recruitment among animals inoculated with MVA or MVA-GFP. (springer.com)
  • TLC or total leukocyte count is a blood test that measures the number of white blood cells in the body. (buddymd.com)
  • What Is TLC or Total Leukocyte Count? (buddymd.com)
  • Hello total count more than 12000 sugests of infections if not treated with appropriate antibiotics the infection increases and it will lead to septicaemia it's bettr to take the medication prescribed by your doctor consult physician for further evaluation and treatment. (practo.com)
  • The OR (95% CI) for high leukocyte of the highest GGT quartile was 2.19 (1.05-4.58) for boys and 2.36 (1.13-4.93) for girls after adjusting for age, BMI, blood pressure, total cholesterol, triglyceride, physical activity, household income, and residential area. (yonsei.ac.kr)
  • to evaluate whether total and differential WBC counts are altered in young obese patients (aged 6-12 years) and if a relationship exists between WBC counts and the severity of obesity as well as with CRP level. (openbiochemistryjournal.com)
  • Total WBC count was performed by using an automatic blood cell counter. (openbiochemistryjournal.com)
  • Apart from an infection or inflammation, WBC count in blood can also be affected by other conditions like disorders of the immune system, autoimmune conditions, cancer, etc. (1mg.com)
  • The purpose of this study was to evaluate the relationship between leukocyte count, a marker of systemic inflammation, and incidence of SAH in a large cohort study. (beds.ac.uk)
  • Leukocyte count is widely considered a marker of inflammation and is also an independent predictor of cardiometabolic diseases. (yonsei.ac.kr)
  • Leukocyte rolling time, defined as the time it takes for a rolling leukocyte to pass through a defined length of a vessel segment, emerges as a unifying parameter determining the efficiency of inducing firm adhesion, which is a rate-limiting step controlling leukocyte recruitment in inflammation. (nih.gov)
  • We studied the role of preoperative leukocyte count and C-reactive protein (CRP) measurements in the diagnosis of acute appendicitis in fertile-aged women with a clinical suspicion of acute appendicitis. (biomedsearch.com)
  • In particular, what is the clinical value of unelevated leukocyte count and CRP in excluding acute appendicitis in these patients? (biomedsearch.com)
  • The percentages of patients with (1) both values unelevated, (2) only leukocyte count elevated, (3) only CRP value elevated, or (4) both values elevated were calculated within the groups A (uninflamed appendix) and B (acute appendicitis). (biomedsearch.com)
  • Taken together, 24 patients were operated on for a clinical suspicion of acute appendicitis, although preoperative leukocyte count and CRP values were unelevated. (biomedsearch.com)
  • Top Japanese sprinters were evaluated for their physical condition, autonomic function, blood chemistry, differential leukocyte count and blood lactate level before and after short, maximal exercise to explore methods of quantifying their conditioning level. (scirp.org)
  • MATERIALS AND METHODS: A retrospective analysis of patients included in the Stockholm I and II trials, randomising patients to surgery alone or to 5 x 5 Gy with immediate surgery, identified pre- and postoperative leukocyte values for 274 patients. (diva-portal.org)
  • METHODS Procalcitonin, C reactive protein, and leucocyte count were measured in 175 children, median age 16 months, on admission to the PICU. (bmj.com)
  • In this paper, we present two methods for enumerating leukocytes on a centrifugal platform using a custom-built fluorescent microscope, nuclear staining, and image processing. (microfluidics-news.com)
  • Generating standard curves using porcine blood sample controls, we observed strong linear fits to measured cell counts using both methods. (microfluidics-news.com)
  • METHODS: A nationwide cross-sectional study was conducted to examine the relationship between GGT and leukocyte count in 830 boys and 714 girls (aged 10-18 years), using data from the 2010-2012 Korean National Health and Nutrition Examination Survey. (yonsei.ac.kr)
  • The manual differential can identify cell types that are not counted by automated methods and detect clinically significant changes in the appearance of white blood cells. (wikipedia.org)
  • Absolute counts are usually reported in units of cells per microliter (µL) or 109 cells per liter (L). The result are then compared against reference ranges, which are defined by individual laboratories and may vary due to different patient populations and testing methods. (wikipedia.org)
  • abstract = "Enumerating specific cell types from whole blood can be very useful for research and diagnostic purposes - e.g., for counting of CD4 and CD8 T cells in HIV/AIDS diagnostics. (illinois.edu)
  • In univariable analysis C3, CRP and leukocyte count, but not ESR, were significantly correlated with HOMA index. (diabetesjournals.org)
  • Platelet and leukocyte counts were not significantly altered in episodes caused by diarrhea and other gastrointestinal symptoms. (ajtmh.org)
  • At 180 min after declamping, the PMN count in both the non-dependent and dependent regions of the isoflurane pre-treated lungs was significantly lower than that of the controls. (nih.gov)
  • If the count is significantly below normal levels, it may be attributed to a viral infection such as influenza, hepatitis, or rubella. (biomedcentral.com)
  • Compared with values measured at the edge of the ear and in the contralateral ear, leukocyte adhesion was found to be diminished significantly in vessels inside the ear tumor in both mouse models. (aacrjournals.org)
  • Surprisingly, the level of leukocyte adhesion in ear venules of mice with a large flank tumor was also reduced significantly. (aacrjournals.org)
  • Leukocyte recruitment in CD18 null but not wild-type mice is significantly blocked by an mAb to E-selectin. (nih.gov)
  • The accuracy of the World Health Organization method of estimating malaria parasite density from thick blood smears by assuming a white blood cell (WBC) count of 8,000/μL has been questioned in several studies. (biomedcentral.com)
  • Giemsa-stained thick films for qualitative and quantitative diagnosis and enumeration of malaria pigment, or haemozoin (Hz)-containing leukocytes (PCL) were performed, and full blood counts (FBC) were generated with a Cell Dyn 3000 ® instrument. (biomedcentral.com)
  • Malaria is known to cause several changes in full blood count (FBC) parameters, of which the most prominent are anaemia and thrombocytopaenia [ 1 ]. (biomedcentral.com)
  • Compared to the lowest quartile, the ORs (95% CI) of the highest quartile for high CRP and leukocyte count were 2.03 (1.50-2.76) and 1.54 (1.13-2.10) after adjusting for age, sex, body mass index, smoking status, alcohol intake, fasting plasma glucose, log-transformed triglyceride and HDL-cholesterol levels. (elsevier.com)
  • Compared with those in the lowest quartile of leukocyte count, those in the highest had an increased risk of IS (adjusted HR 1.75, 95% CI 1.08 to 2.82). (elsevier.com)
  • Differential leucocyte count and the risk of future coronary artery disease in healthy men and women: the EPIC-Norfolk Prospective Population Study. (semanticscholar.org)
  • BACKGROUND We examined the relationship between granulocyte, lymphocyte and monocyte counts and risk of coronary heart disease (CHD) and cardiovascular disease (CVD) in men and women. (semanticscholar.org)
  • Objective: An increased leukocyte count is positively associated with poor outcomes and all-cause mortality in coronary heart disease, cancer, and ischemic stroke. (current-neurovascular-research.com)
  • Leukocyte count appears to be an indicator of a person's future risk of major coronary heart disease events. (elsevier.com)
  • That study showed a relationship between the level of platelet leukocyte aggregates in patients with acute coronary syndrome. (clinicaltrials.gov)
  • The role of leukocyte count in acute ischemic stroke (AIS) remains important. (current-neurovascular-research.com)
  • Objective: To investigate the hypothesis that relative elevations in leukocyte count in a stroke-free population predict future ischemic stroke (IS). (elsevier.com)
  • Feeding mice palm carotene prevents DNA damage in bone marrow and reduction of peripheral leukocyte counts, and enhances survival following X-ray irradiation. (oup.com)
  • This study examined the effects of palm carotene feeding on DNA damage of bone marrow, recovery of peripheral leukocyte counts, and the survival of mice that received whole-body X-ray irradiation. (oup.com)
  • When mice received X-ray (1.5 Gy), marked DNA damage in bone marrow and reduction of peripheral leukocyte count were observed. (oup.com)
  • Once the condition subsides, WBC production by the bone marrow decreases and their count in circulation falls back to normal levels. (1mg.com)
  • Leukocytes, derived from bone marrow stem cells, are the first line of defense of the immune system. (biomedcentral.com)
  • Both meals increased granulocytes' count and reduced the lipoperoxidation induced by both exogenous free radicals and reactive oxygen species (ROS) produced by oxidative burst. (hindawi.com)
  • A fertile-aged woman with right lower abdominal pain but unelevated leukocyte count and C-reactive protein. (biomedsearch.com)
  • OBJECTIVE To evaluate diagnostic markers of infection in critically ill children, comparing procalcitonin with C reactive protein and leucocyte count in a paediatric intensive care unit (PICU). (bmj.com)
  • Area under the ROC curve was 0.96 for procalcitonin, 0.83 for C reactive protein, and 0.51 for leucocyte count. (bmj.com)
  • Risk factors not currently part of the Framingham model (nontraditional risk factors) include high sensitivity C-reactive protein (hs-CRP), ankle-brachial index (ABI), leukocyte count. (uspreventiveservicestaskforce.org)
  • Plasma concentrations of C reactive protein, serum amyloid A protein, and serum albumin and leucocyte count. (bmj.com)
  • Circulating concentrations of C reactive protein, serum amyloid A protein, and serum albumin and the leucocyte count can fluctuate widely during acute responses to tissue damage or infection. (bmj.com)
  • Leukocytes, C-reactive protein, children obesity. (openbiochemistryjournal.com)
  • Our second model is an extension which accounts for extra variation in the leukocyte count due to a treatment adversity, infections, using C-reactive protein as a surrogate. (jyu.fi)
  • Peritonitis was defined by fever, abdominal pain, and cloudy effluent with a leukocyte count greater than 100/mm3 or a positive dialysis effluent culture for microorganisms. (biomedsearch.com)
  • The aim of this study was to establish the effectiveness of platelet and leukocyte counts in the differential diagnosis of fever in the returning traveler. (ajtmh.org)
  • Initial platelet and leukocyte counts might be useful for the clinical differential diagnosis of fever in the returning traveler. (ajtmh.org)
  • If the count exceeds this amount, it is usually caused by an acute infection such as appendicitis, smallpox, or rheumatic fever. (biomedcentral.com)
  • ECs 3 can influence the selection of leukocyte subtypes that compose the immune infiltrate by regulating adhesion molecule expression. (aacrjournals.org)
  • The aim of this study was to estimate the prevalence of abnormal leukocyte count (either low or high) and identify factors associated with high WBC counts in a sample of Saudi patients with SCD. (dovepress.com)
  • Abnormal leukocyte count was common: approximately five in ten Saudi SCD patients assessed in this sample. (dovepress.com)
  • Leucocyte Count Test is to be followed up with other tests to determine the exact cause of the abnormal results, if any. (1mg.com)
  • It is important to realize an abnormal variation in the leukocytes. (biomedcentral.com)
  • Clinical neutrophil hypersegmentation has been widely used as an indicator of B12 or folate deficiency.Biomedical technologists can currently recognize abnormal leukocytes using human eyes. (biomedcentral.com)
  • There may also be less common reasons for abnormal WBC counts. (medlineplus.gov)
  • The manual differential, in which white blood cells are counted on a stained microscope slide, is now performed to investigate abnormal results from the automated differential, or upon request by the healthcare provider. (wikipedia.org)
  • However, there was a fairly good agreement between the number of eosinophils counted with the three techniques in asthmatics and in exacerbated chronic bronchitics, suggesting that sputum cell analysis may be used for a noninvasive assessment of airway eosinophilia. (nih.gov)
  • The decrease in glucose concentration was directly proportional to both the leukocyte count and preanalytical time, confirming unusually high leukocyte-mediated in vitro glucose consumption (3, 4). (thefreedictionary.com)
  • 0.0001), although the association between low serum albumin concentration and leucocyte count was weaker (P=0.08). (bmj.com)
  • Incidence of SAH in relation to baseline leukocyte concentration was studied during a mean follow-up of 27 years in participants free from previous stroke. (beds.ac.uk)
  • The hazard ratio for SAH per one standard deviation (2.01 × 10 9 cells/L) increase of leukocyte concentration was 1.26 (95% CI 1.05-1.53, p = 0.014) after adjustment for several potential confounding factors including smoking. (beds.ac.uk)
  • Leukocyte concentration in relation to incidence of SAH has, to our best knowledge, not earlier been studied. (beds.ac.uk)
  • High leukocyte count at baseline was associated with increased incidence of SAH, although this relationship might be restricted to smokers. (beds.ac.uk)
  • Results: Among 3,103 stroke-free community participants (mean age 69.2 ± 10.3 years) with baseline leukocyte levels measured, median follow-up was 5.2 years. (elsevier.com)
  • The difference was due to a lower granulocyte count, as well as a lower monocyte count in PDS. (mysciencework.com)
  • Monocyte count was also enhanced 2.3 times. (bisp-surf.de)
  • The relation of the leukocyte count to cancer mortality appears to be due to its close association with cigarette smoking, which raises the incidence of certain cancers and can hasten death attributed to cancer. (nih.gov)
  • The aim was to assess postoperative morbidity and mortality in relation to leukocyte reaction and the time interval between radiotherapy and surgery. (diva-portal.org)
  • It is also possible through the APP to check the final percentage of each leukocyte count. (shouthindi.com)
  • Express the count as percentage. (indianmedicinalplants.info)
  • Although the blast percentage and count were decreased in flight mice, the CD34(+) population was increased. (spacestationresearch.com)
  • Different WBCs are seen which are counted in percentage. (medstudentscorner.com)
  • Percentage of various types of white cell is calculated by counting the different cells in various squares. (medstudentscorner.com)
  • This blood test measures the percentage of each type of white blood cell or leukocyte in your blood. (buddymd.com)
  • We studied the prognostic value of the third-day dialysis effluent leukocyte count after antibiotic therapy for prediction of treatment outcomes. (biomedsearch.com)
  • Since epidemiological investigations, anti-malarial efficacy trials and routine laboratory reporting in Papua New Guinea (PNG) have all relied on this approach, its validity was assessed as part of a trial of artemisinin-based combination therapy, which included blood smear microscopy and automated measurement of leucocyte densities on Days 0, 3 and 7. (biomedcentral.com)
  • It is essential to extract the leukocyte region from a blood smear image in order to develop an automatic leukocyte recognition system. (biomedcentral.com)
  • Insensitive to the variance of images, the LNS (Leukocyte Nuclei Segmentation) method functioned well to isolate the leukocyte nuclei from a blood smear image with much better UR (Under Segmentation Rate), ER (Overall Error Rate), and RDE (Relative Distance Error). (biomedcentral.com)
  • In a manual differential, a stained blood smear is examined under a microscope and white blood cells are counted and classified based on their appearance. (wikipedia.org)
  • Association Between Eosinophilic Leukocyte Count and Hematoma Expansion in Acute Spontaneous Intracerebral Hemorrhage. (annals.org)
  • Also called leukocyte , white cell , white corpuscle . (thefreedictionary.com)
  • Analysis indicates that this decline in white cell count with time is not related to exposure to the 1945 atomic bombs, to sex, to age, to commonly diagnosed diseases, or to the disproportionate influence of a subgroup. (osti.gov)
  • A count of the number of white blood cells per unit volume in venous blood . (lymphedemapeople.com)
  • A differential leukocyte count measures the relative numbers of the different types of white cells. (lymphedemapeople.com)
  • High white blood cell (WBC) count is an indicator of sickle cell disease (SCD) severity, however, there are limited studies on WBC counts in Saudi Arabian patients with SCD. (dovepress.com)
  • The results of the study demonstrated significant alterations in autonomic parameters and differential white blood cell count in response to maximal exercise. (scirp.org)
  • 68 proved bacterial and 100 proved cases of viral infections are studied from the point of view of diagnosis using white blood cell counts and other characteristics. (nus.edu.sg)
  • Read more: WBC (white blood cell) count. (bitsosob.gq)
  • Six patients with various forms of leukaemia had neurological signs and symptoms associated with an extremely high white blood cell count and increased whole blood (but not plasma) viscosity. (isharonline.org)
  • Leukocytes or white blood cells (WBCs) are blood cells which form an integral part of the immune system of the body. (1mg.com)
  • These include erythrocytes or red blood cells, leukocytes or white blood cells, and platelets. (1mg.com)
  • Inbrief white blood cells are counted in diluted blood and actual count is calculated by multiplying it by dilution factor. (medstudentscorner.com)
  • The white blood cells are counted in 64 smaller squares by applying Thomas rule. (medstudentscorner.com)
  • Leukocytes are white colored blood cells which defend our body against infections and diseases. (buddymd.com)
  • Decrease in white blood cells count is called leukopenia. (buddymd.com)
  • Increase in white blood cells count is called leukocytosis. (buddymd.com)
  • Most EM docs I know love regaling each other with stories of the CT showing acute appy and the surgeon asking "what's the white count? (blogspot.com)
  • Recent genome-wide association studies identified variants in DARC and CXCL2 genes, and in ORMDL3-GSDMA-CSF3 locus on chromosome 17q21 that influence white blood cell and neutrophil counts in healthy individuals. (cdc.gov)
  • The parameters which are obtained routinely for white blood cell counts include: capacity - electrical conductivity (conductivity) - dispersion (scatter), and volume. (clinicaltrials.gov)
  • A WBC count is a blood test to measure the number of white blood cells (WBCs) in the blood. (medlineplus.gov)
  • White blood cells (also called leukocytes or leucocytes and abbreviated as WBCs) are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders. (wikipedia.org)
  • The number of leukocytes in the blood is often an indicator of disease , and thus the white blood cell count is an important subset of the complete blood count . (wikipedia.org)
  • The normal white cell count is usually between 4 × 10 9 /L and 1.1 × 10 10 /L. In the US, this is usually expressed as 4,000 to 11,000 white blood cells per microliter of blood. (wikipedia.org)
  • In the automated differential, a blood sample is loaded onto an analyzer, which samples a small volume of blood and measures various properties of white blood cells to produce a differential count. (wikipedia.org)
  • This machine used electrical impedance measurements to count cells and determine their sizes, allowing white and red blood cells to be enumerated. (wikipedia.org)
  • The white blood cell differential is a common blood test that is often ordered alongside a complete blood count. (wikipedia.org)
  • The laboratory test results revealed a leukocyte count of 7. (thefreedictionary.com)
  • The promising interim results from this ongoing clinical trial indicate that single-agent GCS-100 induces apoptosis (programmed cell death) in patients' CLL cells, reduces leukocyte count in some patients and is generally well tolerated. (thefreedictionary.com)
  • For each episode of peritonitis, the leukocyte count of the effluent was measured on the third day after initiation of empiric therapy and culture results were recorded. (biomedsearch.com)
  • Our results are a first step towards establishing leukocyte count baselines for the Antarctic pack ice seals off the western Antarctic Peninsula. (springer.com)
  • In addition, it has been established both in vitro (13) and in vivo (14) that suppressed adhesion molecule expression by angiogenic factors results in diminished leukocyte-vessel wall interactions. (aacrjournals.org)
  • Depending on the condition, the count of one or more types of WBCs remains high in the blood. (1mg.com)
  • Diluted specimen of blood with stained WBCs is loaded on to haemocytometer and the cellular elements are counted. (medstudentscorner.com)
  • Track method is usually used to count WBCs. (medstudentscorner.com)
  • WBCs are also called leukocytes. (medlineplus.gov)
  • Leukocyte levels were measured at enrollment, and participants were followed annually for IS, myocardial infarction (MI), and cause-specific mortality. (elsevier.com)
  • Like this the smear is moved in a zigzag manner till 100 cells are counted and entered. (indianmedicinalplants.info)
  • 3.The differential cells are counted manually. (medstudentscorner.com)
  • Longitudinal pattern method or lengthwise method is also used) in which cells are countered in consecutive fields in strips or rows from the tail end straight back towards the thitk end of film i.e. cells are counted in one direction and then field is shifted and counting is done in opposite direction. (medstudentscorner.com)
  • CONCLUSIONS: Impaired postoperative leukocyte reaction is frequent after short-course radiotherapy and increases the risk of postoperative complications and death. (diva-portal.org)
  • CONCLUSIONS: The present study demonstrates a positive relationship between serum GGT and leukocyte count. (yonsei.ac.kr)
  • Differential counts of leukocytes were performed on cytospin preparations of sputum and BAL. (nih.gov)
  • In children with UTIs, uNGAL levels may be associated with blood leukocyte differential counts. (chikd.org)
  • Leukocyte differential counts have long been used to determine the cause of infection [ 13 - 17 ]. (chikd.org)
  • In the 1970s, two techniques were developed for performing automated differential counts: digital image processing of microscope slides and flow cytometry techniques using light scattering and cell staining. (wikipedia.org)
  • Pigment-containing leukocytes (PCL) are more readily detected by automated scatter flow cytometry than by microscopy. (biomedcentral.com)