The thin noncellular outer covering of the CRYSTALLINE LENS composed mainly of COLLAGEN TYPE IV and GLYCOSAMINOGLYCANS. It is secreted by the embryonic anterior and posterior epithelium. The embryonic posterior epithelium later disappears.
A transparent, biconvex structure of the EYE, enclosed in a capsule and situated behind the IRIS and in front of the vitreous humor (VITREOUS BODY). It is slightly overlapped at its margin by the ciliary processes. Adaptation by the CILIARY BODY is crucial for OCULAR ACCOMMODATION.
Hard or soft soluble containers used for the oral administration of medicine.
The making of a continuous circular tear in the anterior capsule during cataract surgery in order to allow expression or phacoemulsification of the nucleus of the lens. (Dorland, 28th ed)
Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
Pieces of glass or other transparent materials used for magnification or increased visual acuity.
A darkly stained mat-like EXTRACELLULAR MATRIX (ECM) that separates cell layers, such as EPITHELIUM from ENDOTHELIUM or a layer of CONNECTIVE TISSUE. The ECM layer that supports an overlying EPITHELIUM or ENDOTHELIUM is called basal lamina. Basement membrane (BM) can be formed by the fusion of either two adjacent basal laminae or a basal lamina with an adjacent reticular lamina of connective tissue. BM, composed mainly of TYPE IV COLLAGEN; glycoprotein LAMININ; and PROTEOGLYCAN, provides barriers as well as channels between interacting cell layers.
Artificial implanted lenses.
Lenses designed to be worn on the front surface of the eyeball. (UMDNS, 1999)
An envelope of loose gel surrounding a bacterial cell which is associated with the virulence of pathogenic bacteria. Some capsules have a well-defined border, whereas others form a slime layer that trails off into the medium. Most capsules consist of relatively simple polysaccharides but there are some bacteria whose capsules are made of polypeptides.
Non-invasive, endoscopic imaging by use of VIDEO CAPSULE ENDOSCOPES to perform examination of the gastrointestinal tract, especially the small bowel.
The anterior aspect of the casing that surrounds the natural CRYSTALLINE LENS.
Clouding or loss of transparency of the posterior lens capsule, usually following CATARACT extraction.
The normal decreasing elasticity of the crystalline lens that leads to loss of accommodation.
The removal of a cataractous CRYSTALLINE LENS from the eye.
A heterogeneous family of water-soluble structural proteins found in cells of the vertebrate lens. The presence of these proteins accounts for the transparency of the lens. The family is composed of four major groups, alpha, beta, gamma, and delta, and several minor groups, which are classed on the basis of size, charge, immunological properties, and vertebrate source. Alpha, beta, and delta crystallins occur in avian and reptilian lenses, while alpha, beta, and gamma crystallins occur in all other lenses.
The deposition of flaky, translucent fibrillar material most conspicuous on the anterior lens capsule and pupillary margin but also in both surfaces of the iris, the zonules, trabecular meshwork, ciliary body, corneal endothelium, and orbital blood vessels. It sometimes forms a membrane on the anterior iris surface. Exfoliation refers to the shedding of pigment by the iris. (Newell, Ophthalmology, 7th ed, p380)
The posterior aspect of the casing that surrounds the natural CRYSTALLINE LENS.
Insertion of an artificial lens to replace the natural CRYSTALLINE LENS after CATARACT EXTRACTION or to supplement the natural lens which is left in place.
The dioptric adjustment of the EYE (to attain maximal sharpness of retinal imagery for an object of regard) referring to the ability, to the mechanism, or to the process. Ocular accommodation is the effecting of refractive changes by changes in the shape of the CRYSTALLINE LENS. Loosely, it refers to ocular adjustments for VISION, OCULAR at various distances. (Cline et al., Dictionary of Visual Science, 4th ed)
The front third of the eyeball that includes the structures between the front surface of the cornea and the front of the VITREOUS BODY.
The sac enclosing a joint. It is composed of an outer fibrous articular capsule and an inner SYNOVIAL MEMBRANE.
A procedure for removal of the crystalline lens in cataract surgery in which an anterior capsulectomy is performed by means of a needle inserted through a small incision at the temporal limbus, allowing the lens contents to fall through the dilated pupil into the anterior chamber where they are broken up by the use of ultrasound and aspirated out of the eye through the incision. (Cline, et al., Dictionary of Visual Science, 4th ed & In Focus 1993;1(1):1)
Soft, supple contact lenses made of plastic polymers which interact readily with water molecules. Many types are available, including continuous and extended-wear versions, which are gas-permeable and easily sterilized.
The portion of the crystalline lens surrounding the nucleus and bound anteriorly by the epithelium and posteriorly by the capsule. It contains lens fibers and amorphous, intercellular substance.
A scientific tool based on ULTRASONOGRAPHY and used not only for the observation of microstructure in metalwork but also in living tissue. In biomedical application, the acoustic propagation speed in normal and abnormal tissues can be quantified to distinguish their tissue elasticity and other properties.
A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH).
A pill sized videocamera encased in a capsule. It is designed to be swallowed and subsequently traverse the gastrointestinal tract while transmitting diagnostic images along the way.
Nitrous acid (HNO2). A weak acid that exists only in solution. It can form water-soluble nitrites and stable esters. (From Merck Index, 11th ed)
The core of the crystalline lens, surrounded by the cortex.
Diseases affecting the eye.
Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.
A ring of tissue extending from the scleral spur to the ora serrata of the RETINA. It consists of the uveal portion and the epithelial portion. The ciliary muscle is in the uveal portion and the ciliary processes are in the epithelial portion.
Connective tissue comprised chiefly of elastic fibers. Elastic fibers have two components: ELASTIN and MICROFIBRILS.
WHITE MATTER pathway, flanked by nuclear masses, consisting of both afferent and efferent fibers projecting between the WHITE MATTER and the BRAINSTEM. It consists of three distinct parts: an anterior limb, posterior limb, and genu.
The most anterior portion of the uveal layer, separating the anterior chamber from the posterior. It consists of two layers - the stroma and the pigmented epithelium. Color of the iris depends on the amount of melanin in the stroma on reflection from the pigmented epithelium.
Hydrophilic contact lenses worn for an extended period or permanently.
Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.
Incomplete rupture of the zonule with the displaced lens remaining behind the pupil. In dislocation, or complete rupture, the lens is displaced forward into the anterior chamber or backward into the vitreous body. When congenital, this condition is known as ECTOPIA LENTIS.
Resistance and recovery from distortion of shape.
Sterile solutions used to clean and disinfect contact lenses.
Non-collagenous, calcium-binding glycoprotein of developing bone. It links collagen to mineral in the bone matrix. In the synonym SPARC glycoprotein, the acronym stands for Secreted Protein, Acidic and Rich in Cysteine.
One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
A species of the genus MACACA which typically lives near the coast in tidal creeks and mangrove swamps primarily on the islands of the Malay peninsula.
The transparent, semigelatinous substance that fills the cavity behind the CRYSTALLINE LENS of the EYE and in front of the RETINA. It is contained in a thin hyaloid membrane and forms about four fifths of the optic globe.
Ubiquitous macromolecules associated with the cell surface and extracellular matrix of a wide range of cells of vertebrate and invertebrate tissues. They are essential cofactors in cell-matrix adhesion processes, in cell-cell recognition systems, and in receptor-growth factor interactions. (From Cancer Metastasis Rev 1996; 15(2): 177-86; Hepatology 1996; 24(3): 524-32)
A non-fibrillar collagen found in the structure of BASEMENT MEMBRANE. Collagen type IV molecules assemble to form a sheet-like network which is involved in maintaining the structural integrity of basement membranes. The predominant form of the protein is comprised of two alpha1(IV) subunits and one alpha2(IV) subunit, however, at least six different alpha subunits can be incorporated into the heterotrimer.
Proteoglycans consisting of proteins linked to one or more CHONDROITIN SULFATE-containing oligosaccharide chains.
Measurements of the height, weight, length, area, etc., of the human and animal body or its parts.
Large, noncollagenous glycoprotein with antigenic properties. It is localized in the basement membrane lamina lucida and functions to bind epithelial cells to the basement membrane. Evidence suggests that the protein plays a role in tumor invasion.
A form of fluorescent antibody technique commonly used to detect serum antibodies and immune complexes in tissues and microorganisms in specimens from patients with infectious diseases. The technique involves formation of an antigen-antibody complex which is labeled with fluorescein-conjugated anti-immunoglobulin antibody. (From Bennington, Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)
Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.
The space in the eye, filled with aqueous humor, bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and that part of the crystalline lens which presents through the pupil. (Cline et al., Dictionary of Visual Science, 4th ed, p109)
The use of photothermal effects of LASERS to coagulate, incise, vaporize, resect, dissect, or resurface tissue.
Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.
A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area.
A heteropolysaccharide that is similar in structure to HEPARIN. It accumulates in individuals with MUCOPOLYSACCHARIDOSIS.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
The properties, processes, and behavior of biological systems under the action of mechanical forces.
Macromolecular organic compounds that contain carbon, hydrogen, oxygen, nitrogen, and usually, sulfur. These macromolecules (proteins) form an intricate meshwork in which cells are embedded to construct tissues. Variations in the relative types of macromolecules and their organization determine the type of extracellular matrix, each adapted to the functional requirements of the tissue. The two main classes of macromolecules that form the extracellular matrix are: glycosaminoglycans, usually linked to proteins (proteoglycans), and fibrous proteins (e.g., COLLAGEN; ELASTIN; FIBRONECTINS; and LAMININ).
An extracellular layer outside the cell wall of a fungus composed of polysaccharides. It may serve a protective role amongst others.
A type of stress exerted uniformly in all directions. Its measure is the force exerted per unit area. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
A double-walled epithelial capsule that is the bulbous closed proximal end of the kidney tubular system. It surrounds the cluster of convoluted capillaries of KIDNEY GLOMERULUS and is continuous with the convoluted PROXIMAL KIDNEY TUBULE.
Chromatography on non-ionic gels without regard to the mechanism of solute discrimination.
In vivo method of screening investigative anticancer drugs and biologic response modifiers for individual cancer patients. Fresh tumor tissue is implanted under the kidney capsule of immunocompetent mice or rats; gross and histological assessments follow several days after tumor treatment in situ.
A type of ion exchange chromatography using diethylaminoethyl cellulose (DEAE-CELLULOSE) as a positively charged resin. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Glycoproteins found on the surfaces of cells, particularly in fibrillar structures. The proteins are lost or reduced when these cells undergo viral or chemical transformation. They are highly susceptible to proteolysis and are substrates for activated blood coagulation factor VIII. The forms present in plasma are called cold-insoluble globulins.
The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Refraction of LIGHT effected by the media of the EYE.

Anterior polar cataracts in CS rats: a predictor of mature cataract formation. (1/316)

PURPOSE: The objective of this study was to characterize the morphology of the anterior opacities formed during recovery from posterior subcapsular cataract (PSC) in Royal College of Surgeons (RCS) rats. METHODS: Lenses from RCS rats at 8 and 12 weeks postnatal (n = 14 and 12, respectively) were examined under a dissecting microscope for the presence of anterior opacities. Lenses with anterior opacities were fixed, embedded in epoxy resin, and sectioned along the optic axis for light microscopy (LM) and transmission electron microscopy (TEM). RESULTS: At eight weeks postnatal, 21.5% of animals (3/14) had anterior cataracts. Light microscopy of 1- to 2-microm-thick sections revealed an anomalous layer of material located at the epithelium-fiber interface, which was identified as a zone of liquefaction by TEM. Epithelial cells had minor structural defects but were not necrotic. Anterior portions of elongating and cortical fibers under the zone of liquefaction were undisrupted, whereas their posterior portions had numerous vacuoles. The anterior opacities were classified as anterior polar cataracts (APCs) based on the location and type of morphologic damage in the affected lenses. At twelve weeks postnatal, 25% of animals (3/12) had APCs that involved prominent vesiculation of the anterior cortex. Ultrastructural examination showed that large vesicles were located between and inside anterior fibers and that most extracellular spaces were abnormally widened. Posteriorly, internalization of the PSC by new fiber growth was disordered and displayed vesiculation and density variations. In the bow region, LM revealed minor structural irregularities that were identified as groups of apparently degenerating fibers by TEM. CONCLUSIONS: APCs in RCS rats are caused by degeneration of elongating fibers in the bow region and subsequent damage in the superficial anterior cortex. The percentage of animals with APCs (25%) was consistent with the percentage of animals in which mature cataracts eventually develop. The morphologic changes, time of onset, and percentage of animals affected suggest that APC is the initial manifestation of mature cataract formation in RCS rats.  (+info)

Loss of heterozygosity in pseudoexfoliation syndrome. (2/316)

PURPOSE: Pseudoexfoliation (PEX) syndrome is characterized by the accumulation of a material of unknown origin in the anterior structures of the eye. Loss of heterozygosity (LOH) in a genetic locus indicates the presence of a gene located in the same region that could be implicated in the development or the progression of a disease. In this study, the occurrence of LOH in tissues involved in PEX and the possible correlation of LOH incidence with clinical parameters were evaluated. METHODS: Twelve iris specimens, 12 anterior capsule specimens, and respective blood samples were obtained from 17 patients with PEX (13 men), who were undergoing glaucoma and cataract surgery. Sixteen anterior capsule specimens and four iris specimens were obtained from 16 patients without PEX. Polymerase chain reaction was used to amplify 10 highly polymorphic microsatellite markers located on chromosomes 1, 7, 9, and 13. RESULTS: Overall, 83.3% (20/24) of PEX specimens and 94.11% (16/17) of patients with PEX had LOH. The highest incidence of LOH was observed in marker D13S175 (41.6%) followed by D7S478 and D7S479 (37.5%). Only three non-PEX specimens displayed LOH. The number of loci lost was directly related to the altitude of the patients' present residence, but the number lost did not differ significantly between the iris and capsule samples. CONCLUSIONS: The occurrence of LOH in tissues involved in PEX implies a genetic role in PEX pathogenesis at a cellu lar level. The correlation of LOH incidence with the altitude of the patient's residence, could indicate an increased susceptibility to UV radiation of the chromosomal regions examined.  (+info)

Biometric, optical and physical changes in the isolated human crystalline lens with age in relation to presbyopia. (3/316)

The biometric, optical and physical properties of 19 pairs of isolated human eye-bank lenses ranging in age from 5 to 96 years were compared. Lens focal length and spherical aberration were measured using a scanning laser apparatus, lens thickness and the lens surface curvatures were measured by digitizing the lens profiles and equivalent refractive indices were calculated for each lens using this data. The second lens from each donor was used to measure resistance to physical deformation by providing a compressive force to the lens. The lens capsule was then removed from each lens and each measurement was repeated to ascertain what role the capsule plays in determining these optical and physical characteristics. Age dependent changes in lens focal length, lens surface curvatures and lens resistance to physical deformation are described. Isolated lens focal length was found to be significantly linearly correlated with both the anterior and posterior surface curvatures. No age dependent change in equivalent refractive index of the isolated lens was found. Although decapsulating human lenses causes similar changes in focal length to that which we have shown to occur when human lenses are mechanically stretched into an unaccommodated state, the effects are due to nonsystematic changes in lens curvatures. These studies reinforce the conclusion that lens hardening must be considered as an important factor in the development of presbyopia, that age changes in the human lens are not limited to the loss of accommodation that characterizes presbyopia but that the lens optical and physical properties change substantially with age in a complex manner.  (+info)

Molecular architecture of the lens fiber cell basal membrane complex. (4/316)

Lens fiber cells are transparent, highly elongated, epithelial cells. Because of their unusual length these cells represent a novel model system to investigate aspects of epithelial cell polarity. In this study, we examined the fiber cell basal membrane complex (BMC). The BMC anchors fiber cells to the lens capsule and facilitates their migration across the capsule. Confocal microscopy revealed that bundled actin filaments converge beneath the center of each BMC and insert into the lateral membrane at points enriched in N-cadherin. Two other contractile proteins, caldesmon and myosin, were enriched in the BMC, co-localizing with f-actin bundles. The actin/N-cadherin complex formed a hexagonal lattice, cradling the posterior face of the lens. Removal of the capsule caused the tips of the fiber cells to break off, remaining attached to the stripped capsule. This provided a method for assaying cell adhesion and purifying BMC components. Fiber cell adhesion required Mg2+ and/or Ca2+ and was disrupted by incubation with beta1 integrin antibody. BMC proteins were compared with samples from the neighboring lateral membrane. Although some components were common to both samples, others were unique to the BMC. Furthermore, some lateral membrane proteins, most notably lens major intrinsic protein (MIP), were excluded from the BMC. Western blotting of BMC preparations identified several structural proteins originally found in focal adhesions and two kinases, FAK and MLCK, previously undescribed in the lens. These data suggest that the BMC constitutes a distinct membrane domain in the lens. The structural organization of the BMC suggests a role in shaping the posterior lens face and hence the refractive properties of the eye.  (+info)

Digital image capture and automated analysis of posterior capsular opacification. (5/316)

PURPOSE: To develop and validate a digital imaging and analysis technique for assessing the extent of posterior capsular opacification after cataract surgery. METHODS: Retroillumination images of the posterior capsule were obtained by using a digital camera mounted on a slit lamp. The images were analyzed using an available image analysis software program. The image acquisition and analysis techniques were tested for face validity, reproducibility, and the ability to detect progression of capsular opacity over time. RESULTS: Digital retroillumination images were obtained without patient discomfort. Automated analysis of images correlated well with clinical grading both at slit lamp examination and when looking at the images themselves (Spearman's correlation coefficient >0.7). Analysis of images taken at different times showed high reproducibility (intraclass correlation >0.9), and the system was able to identify progression of capsular opacity over a 2-year period with a mean increase of 15.8% in progressors versus an increase of 0.6% in nonprogressors (P < 0.05). CONCLUSIONS: Digital retroillumination images of the posterior capsule can be obtained reliably, and automated analyses correlate well with clinical assessment. The system presented here uses commercially available instruments and software, and it is practical for use in longitudinal studies of posterior capsule opacification. It is reliable, easy to use, and can detect small changes in the percentage area covered by posterior capsule opacification over time.  (+info)

The effect of the haptic portion of intraocular lens on the development of posterior capsular opacification in rabbit. (6/316)

Using a white rabbit model, the effect of the haptic portion of the intraocular lens (IOL) and intracapsular ring on the development of posterior capsular opacification (PCO) after extracapsular cataract extraction (ECCE) with phacoemulsification was studied. Implantation of both the intracapsular ring and IOL developed less PCO than implantation of the IOL alone. ECCE followed by implantation of the intracapsular ring alone also developed less PCO than ECCE alone. Through this experimental work in a rabbit model, it could be conceived that the haptic portion of IOL and the intracapsular ring can prevent the development of PCO.  (+info)

Uveitis induced by lymphocytes sensitized against a transgenically expressed lens protein. (7/316)

PURPOSE: Previously established experimental models for lens-associated uveitis (LAU) are all mediated by antibodies. The present study analyzed the features of a novel experimental intraocular inflammatory eye disease that is mediated by lymphocytes targeted at a lens antigen. METHODS: Conventional technologies were used to generate three lines of transgenic (Tg) mice, expressing hen egg lysozyme (HEL) under the control of the alphaA-crystallin promoter. To induce intraocular inflammation, these Tg mice were injected with lymphocytes from syngeneic wild-type donors sensitized against HEL. Before their injection, the cells were stimulated in culture with HEL. To release lenticular material, some eyes were capsulotomized. Ocular histopathologic changes were examined by routine methods. Levels of HEL antibody were measured by enzyme-linked immunosorbent assay, whereas cellular immunity was determined by the lymphocyte proliferation assay. RESULTS: Intraocular inflammation developed in HEL-Tg mice injected with syngeneic lymphocytes sensitized against HEL. The severity of inflammation was directly related to the number of injected cells, as well as to the accessibility of HEL. The most intense inflammation was seen in Tg mice in which the lens was disintegrated due to high production of HEL. In mice with no apparent lenticular changes the inflammation was enhanced by capsulotomy. The inflammation affected all segments of the eye and persisted for at least 39 days after adoptive transfer of cells. Four days after cell injection, the inflammation consisted of subacute infiltration, with both mononuclear and polymorphonuclear leukocytes, whereas more chronic infiltration was seen at later times. Vigorous cellular immunity but no antibody to HEL was found in recipient mice, thus demonstrating the exclusive participation of cellular immunity in the pathogenesis of this experimental disease. CONCLUSIONS: Transgenic mice expressing HEL in their lenses develop intraocular inflammation after injection of syngeneic lymphocytes sensitized against HEL. This experimental disease is a novel cell-mediated model for LAU.  (+info)

Lens cell populations studied in human donor capsular bags with implanted intraocular lenses. (8/316)

PURPOSE: Posterior capsule opacification is an ongoing cellular redistribution process. The level of viable cell coverage was therefore determined in human donor capsular bags with implanted intraocular lenses, and cellular morphology and ultrastructure were investigated in relation to cell type and level of differentiation. METHODS: Donor capsular bags, retrieved at intervals of 4 months to 13 years after surgery, were investigated by phase optics before fixation. Postfixation techniques included scanning electron microscopy and transmission electron microscopy of sections and immunofluorescent staining of cytoskeletal proteins in wholemounts. RESULTS: All the capsular bags contained a large population of viable cells on the capsular surfaces. Cells on the anterior face of the anterior capsule and in the spaces around the intraocular lens had an elongated morphology and expressed alpha-smooth muscle actin. The cells formed light-scattering, multilayered aggregates and strands that were surrounded by layers of extracellular matrix. The regions between the intraocular lens and the equator of the bags were populated by monolayers of epithelial cells of normal morphology and ultrastructure, on both the anterior and posterior capsules. In some regions the apical surfaces of the two epithelial monolayers were in contact, and in some parts of the equatorial regions, differentiation of cells into well-organized fiberlike cells was evident. CONCLUSIONS: Human capsular bags contain a large population of viable cells for many years after cataract surgery. Cells in the regions around the intraocular lens undergo transition to a mesenchymal type. Cells peripheral to these regions can form a stable closed microenvironment in which both normal epithelial morphology and differentiation to fiberlike cells are maintained.  (+info)

Definition of capsular tension ring in the Legal Dictionary - by Free online English dictionary and encyclopedia. What is capsular tension ring? Meaning of capsular tension ring as a legal term. What does capsular tension ring mean in law?
Senescence is a leading cause of age-related cataract (ARC). The current study indicated that the senescence-associated protein, p53, total laminin (LM), LMα4, and transforming growth factor-beta1 (TGF-β1) in the cataractous anterior lens capsules (ALCs) increase with the grades of ARC. In cataractous ALCs, patient age, total LM, LMα4, TGF-β1, were all positively correlated with p53. In lens epithelial cell (HLE B-3) senescence models, matrix metalloproteinase-9 (MMP-9) alleviated senescence by decreasing the expression of total LM and LMα4; TGF-β1 induced senescence by increasing the expression of total LM and LMα4. Furthermore, MMP-9 silencing increased p-p38 and LMα4 expression; anti-LMα4 globular domain antibody alleviated senescence by decreasing the expression of p-p38 and LMα4; pharmacological inhibition of p38 MAPK signaling alleviated senescence by decreasing the expression of LMα4. Finally, in cataractous ALCs, positive correlations were found between LMα4 and total LM, as well as
TY - JOUR. T1 - Three-Year Incidence and Factors Associated With Posterior Capsule Opacification After Cataract Surgery: The Australian Prospective Cataract Surgery and Age-related Macular Degeneration Study. AU - Fong, Calvin. AU - Mitchell, Paul. AU - Rochtchina, Elena. AU - Cugati, Sudha. AU - Hong, Thomas. AU - Wang, Jie. PY - 2014/1. Y1 - 2014/1. N2 - Purpose To assess 3-year incidence and associated factors of posterior capsule opacification (PCO) after phacoemulsification surgery. Design Cohort study. Methods A total of 1934 consecutive patients aged ≥64 years undergoing phacoemulsification surgery at Westmead Hospital were recruited, of whom 1495 (77.3%) had retroillumination anterior segment images taken of the surgical eyes after 1 month and at a further postoperative visit within 3 years. Severe PCO was defined if the view of the optic disc was obscured, or neodymium-yttrium- aluminum-garnet capsulotomy was performed. Cumulative incidence of PCO was estimated using Kaplan-Meier ...
Purpose : To compare central corneal thickness (CCT), corneal endothelial cell density, and lens capsule thickness in normotensive patients with and without pseudoexfoliation syndrome (PXS) Methods : This was a prospective, comparative, descriptive study. Normotensive candidates for cataract surgery with (study group) and without (control group) PXS were enrolled in the study. CCT ...
YAG capsulotomies are routine procedures used to restore vision after the formation of a secondary cataract, also called posterior capsular opacification.
Posterior capsule opacification (PCO) is a fairly common complication of cataract surgery. Sometimes you can develop a thickening of the back (posterior) of the lens capsule which holds your artificial lens in place.This thickening of the capsule causes your vision to become cloudy. If this happens you may need to have laser treatment to make vision clear again. Once you have had the laser treatment for PCO it doesnt normally cause any long term problem with your sight.
Posterior capsule opacification (PCO) is a fairly common complication of cataract surgery. Sometimes you can develop a thickening of the back (posterior) of the lens capsule which holds your artificial lens in place.This thickening of the capsule causes your vision to become cloudy. If this happens you may need to have laser treatment to make vision clear again. Once you have had the laser treatment for PCO it doesnt normally cause any long term problem with your sight.
Discusses laser surgery called Nd:YAG posterior capsulotomy. Covers cloudiness that may happen after cataract surgery, sometimes called aftercataract. Discusses why surgery is done, how well it works, and risks.
Discusses laser surgery called Nd:YAG posterior capsulotomy. Covers cloudiness that may happen after cataract surgery, sometimes called aftercataract. Discusses why surgery is done, how well it works, and risks.
The lenses of New Zealand White and Flemish Giant rabbits were removed using five techniques representative of the different clinical approaches to extracapsular cataract extraction currently employed. Posterior capsule opacification developed in all experimental animals within 6 weeks of the operat …
Purpose : Many drugs have been loaded onto IOLs by different methods to achieve a sustained and controlled release of drugs to treat posterior capsular opacification (PCO). This study tested the hypothesis that the sustained release of genistein (GEN) from negative charged nanoparticles surface modified IOL by ester bond can prevent the PCO in rabbit eyes effectively and safely.. Methods : Nanostructured lipid carriers (NLCs) loaded with GEN (GEN-NLC) were made by melt emulsification method. GEN-NLCs were attached on IOLs by ester bond formed by the dehydration between the carboxyl group offered by the sodium deoxycholate on the NLC surface and the hydroxy group of hydrophilic acrylic IOLs. The morphology and release of the GEN-NLC on the surface of IOLs and was measured. Sixty New Zealand albino rabbits undergoing phacoemulsification in left eye were randomly and equally divided into three groups. Group A: original IOL; group B: anterior chamber (AC) injection GEN-NLC and original IOL; group C: ...
Aslam and colleagues6 have presented, in the BJO, a systematic analysis of strategies to evaluate posterior capsule opacity and have pointed out that at present there is no entirely satisfactory method of comprehensively quantifying capsule opacity in vivo. In addition to regional quantitation of the optical density of capsule opacity, typically scored subjectively or by analysis of digitised photographs, capsule opacity has fibrotic and lens epithelial proliferative components that require three dimensional measurement. In order to assess the extent of opacification, researchers such as Sacu and colleagues have resorted to multiple modes of evaluation including a subjective score that ranks subtypes of fibrotic opacity, automated analysis of digitised photographs, and need for Nd:YAG laser capsulotomy.4 Hayashi and Hayashi7 have argued that multiple methods are indeed required to adequately describe these various features, and have suggested that retroillumination photography is helpful in ...
Purpose: To determine the qualitative change in stress on the lens capsule during in vivo human accommodation. Methods: Nine subjects [mean age: 30 years, range: 25-38 years] were studied, each of whom had undergone a phakic refractive intraocular lens (PRL) surgical procedure. The change, during accommodation, of stress on the surface of the anterior lens capsule (ALS) was determined by employing high-resolution anterior segment optical coherence tomography (OCT). This was done by comparing the ratio of the intensity of the image from the anterior surface of the natural lens (ALS) to the images of the anterior corneal surface (ACS), posterior corneal surface (PCS), and the posterior surface of the phakic refractive intraocular lens (PPRLS) before and during accommodation. Results: The intensities of the OCT images of the ACS and PPRLS did not significantly change during accommodation when compared to their respective baselines, while the intensity ratios: ALS/ACS, ALS/PCS and ALS/PPRLS all ...
The StabilEyes® Capsular Tension Ring provides exceptional intraoperative stability for cataract patients with zonular weakness.
A synthetic polymer (24) is provided for endocapsular lens (18) replacement in an eye (10). The polymer, whch is injected into the lens capsule (16) after removal of the lens, comprises an oxygen-stabilized photosensitive prepolymer. An example of such a prepolymer comprises polyether with urethane linkages with one or both ends capped with a functional group containing at least one double bond, such as an acrylate, a methacrylate, or a styrene. The polymerization reaction is initiated with a photoinitiator such as dimethoxyphenylacetophenone and is quenched in the presence of oxygen. Contrary to the prior art polymers, the time of curing is on the order of only a minute or so. The viscosity and thickness of the polymer formed may be tailored to achieve a desired index of refraction of between about 1.3 and 1.6.
Nuestros profesionales publican en revistas científicas de alto impacto con el objetivo de ofrecer a nuestros pacientes los últimos tratamientos. Clínica Universidad de Navarra
Abstract: : Purpose: Our aim is to covalently modify intraocular lens implants (IOLs) with death receptor ligands to induce apoptosis in contacting lens epithelial cells (LECs). The clinical goals are prevention of posterior capsular opacification (PCO) and preservation of normal capsule tissue compliance for accommodating IOLs. We have previously demonstrated that primary LECs on lens capsule are resistant to Fas stimulated apoptosis; whereas HLE-B3 LECs are sensitive to Fas ligation when cultured on tissue culture plastic but become Fas resistant when cultured on lens capsule or collagen IV. Here we determine whether Fas ligand modified surfaces can induce apoptosis in LECs using conditions under which they are Fas sensitive. We also initiate exploration of the mechanism of Fas resistance for primary LECs adherent to capsule. Methods: Prototype surfaces were constructed by coupling Fas ligand (FasL) via heterobifunctional polyethylene glycol (PEG) chains to hydroxyethyl methacrylate (HEMA). ...
In myopic eyes and post-vitrectomy eyes, we can get an overly deep anterior chamber during cataract surgery. The infusion pressure from the phaco probe or I/A probe will push the iris against the anterior lens capsule and create a seal. Now that there is less pressure in the vitreous cavity and posterior chamber, this causes…
A common cataract surgery complications is a posterior capsule opacity in the lens implant. A procedure called a YAG laser capsulotomy can quickly and effectively restore vision following posterior capsular opacification.
The scleral pigment, best seen temporal, is found in all affected individual in this bilateral disease. The dark iris is not visible due to the dilated pupil. Pigment can be seen on the anterior lens capsule (black arrows). The pigment and scar on the axial cornea is due to exposure keratitis secondary to buphthalmia. Intraocular pressure at this time was 22mmHg.. ...
Capsular bag distension syndrome (CBDS) (i.e. capsular block syndrome, capsular bag hyperdistension, capsulorhexis block syndrome) is a rare complication of cataract surgery with in the bag intraocular lens placement where turbid fluid builds up behind the intraocular lens and posterior capsule, eventually leading to a decrease in visual acuity for the patient.
Gemini Refractive Capsule. The Gemini Refractive Capsule (Omega Ophthalmics) takes an open-source approach to providing the option of exchangeability to any modern lens design while also stabilizing ELP. The product is an implant that lines the circumference of the capsular bag and provides a defined plane in the middle of the capsule to securely hold a traditional IOL in place. The company is also developing a proprietary hydrophobic acrylic optic that could be used in conjunction with the Gemini Refractive Capsule, either alone or in combination with traditional IOLs, to create new optical systems for low-vision patients or simply to fine-tune refractive outcomes. Additionally, by keeping the capsular bag open, the Gemini Refractive Capsule has been shown to dramatically reduce posterior capsular opacification (PCO). Other nonrefractive devices, such as biometric sensors, are also being developed to fit inside the real estate that is protected by the Gemini Refractive Capsule. With a protected ...
Meacock, W R, Spalton, D J, Hollick, E J, Boyce, J F, Barman, S A and Sanguinetti, G (2000) A double masked prospective ocular safety study of an anti-lens epithelial cell antibody to prevent posterior capsular opacification. Journal of Cataract and Refractive Surgery, 26(5), pp. 716-721. ISSN (print) 0886-3350 ...
We will demonstrate several exercises to stretch out the tight posterior capsule after covering causes of a tight posterior capsule.
Learn more about cataracts and YAG capsulotomy with the eye doctors and ophthalmologists at MN Eye, serving Minneapolis, Minnesota.
Discussion. In the rat lens explant model used in the present study explants cultured with TGFβ then FGF without addition of DEX exhibited many features of PCO development over the 30 day culture period, as reported previously [10]. Cells became multilayered and tended to gather up into plaques, leaving the surrounding lens capsule denuded. These plaques, which arose quite abruptly from the lens capsule, were covered with a thick web of ECM-like material. In addition, cells underwent epithelial-mesenchymal transition, as evidenced by expression of α-smooth muscle actin and fibronectin, non-lens proteins that are typically associated with human PCO.. In this model, significant changes in lens cell behavior occurred when DEX was included throughout the culture period. These included rapid formation of long, needle-like cells early in the culture period and a reduction in the overall extent of thickening of the explant over time, which was associated with a decreased tendency for the lens capsule ...
The pathological development of lens epithelial cells (LECs) leads to posterior capsular opacification (PCO). This studywas undertaken to investigate the effects of microRNA-486-5p (miR-486-5p) on TGF-b2-induced proliferation, invasionand epithelial-mesenchymal transition (EMT) in the lens epithelial cell line SRA01/04, and to explore the underlyingmolecular mechanisms. The expression of miR-486-5p in TGF-b2-induced SRA01/04 cells was down-regulated, and theexpression of Smad2, p-Smad2 and p-Smad3 was up-regulated. A dual-luciferase reporter assay revealed that miR-486-5pdirectly targets the 30-UTR of Smad2. MiR-486-5p mimic transfection markedly down-regulated the expression levels ofSmad2, thus inhibiting the expression of p-Smad2 and p-Smad3. MiR-486-5p overexpression in SRA01/04 cells markedlysuppressed TGF-b2-induced proliferation and invasion, inhibited protein expression of CDK2 and CDK4, down-regulatedfibronectin, a-SMA and vimentin and up-regulated E-cadherin; these effects were partly ...
Capsulotomy is a laser procedure performed at Nicolitx Eye Consultants in Jacksonville to clean secondary cataracts - learn more about this procedure.
0081] Mirror M2 serves to direct the light onto the target, and may be used in a variety of ways. Mirror M2 could be a dichroic element that the user looks through in order to visualize the target directly or using a camera, or may be made as small as possible to provide an opportunity for the user to view around it, perhaps with a binocular microscope. If a dichroic element is used, it may be made to be photopically neutral to avoid hindering the users view. An apparatus for visualizing the target tissue is shown schematically as element V, and is preferably a camera with an optional light source for creating an image of the target tissue. The optional aiming beam AIM may then provide the user with a view of the disposition of the treatment beam, or the location of the identified targets. To display the target only, AIM may be pulsed on when the scanner has positioned it over an area deemed to be a target. The output of visualization apparatus V may be brought back to the system via the ...
The session is intended to provide an understanding of when and how to perform a YAG capsulotomy. It will highlight the risks, benefits, preoperative and postoperative care that is involved with a YAG capsulotomy ...
A knowledge of the indications for Nd:YAG laser capsulotomy and meticulous technique increase the safety of the procedure and the chance of a subsequent improvement in vision for patients.
Synonyms for Anterior subcapsular cataract in Free Thesaurus. Antonyms for Anterior subcapsular cataract. 20 synonyms for cataract: opacity, waterfall, falls, rapids, cascade, torrent, deluge, downpour, Niagara, alluvion, cataclysm, deluge, downpour, flood, freshet. What are synonyms for Anterior subcapsular cataract?
The purpose of this study is to examine the efficacy of a capsular tension ring (CTR) in preventing anterior capsule shrinkage after cataract surgery in exfoliation syndrome (XFS) with no zonular weakness. The eyes with XFS undergo phacoemulsification and aspiration (PEA) with an intraocular lens (IOL) implantation. All operations are performed by a single surgeon. No eyes with either ectopia lentis or phacodonesis are included. There are three groups; CTR is not used in group A, CTR is simply implanted in group B, and CTR is implanted and closed by tying both eyelets in group C. The areas of continuous curvilinear capsulorhexis (CCC) are calculated, and both the time-course change and the comparison among the 3 groups are tested ...
Posterior capsular opacification (PCO) caused by proliferation of residual epithelial cells over the lens equator and onto the posterior lens capsule [1] is the leading cause of visual impairment and blindness after cataract surgery [2-4]. There are currently no effective means by which to eradicate the residual lens epithelial cells during the operation [5,6]. In spite of improvements in the basic research on development of cataracts, surgical techniques, and the material or the design of the intraocular lens, the incidence of PCO is still 8~34.3% in adults, and nearly 100% in children [7-10]. One new promising approach for treatment of PCO is a gene therapy system uses a so-called suicide gene, the herpes simplex virus type 1 thymidine kinase (HSV-tk) gene, and the anti-herpes nucleoside analog drug, ganciclovir (GCV) [11-13]. In this system, GCV is phosphorylated by HSV-tk into a deoxynucleotide analog that becomes incorporated into DNA during strand replacement in proliferating cells, where ...
0024]Typically the human lens capsule of the present invention may be supported on a solid substrate such as a plastics or glass surface, e.g. the surface of a petri dish. Sigma ligands may be first identified as such by conducting, for example, a radioligand binding assay, such as described in WO 00/00599 to ascertain that the test agent is a sigma ligand, before carrying out the method as described above. Importantly, sigma radioligand binding assays determine only that an agent binds to sigma sites and not whether it acts as an agonist or antagonist in functional terms (whether it acts to stimulate or inhibit the receptor). In WO 00/00599 it was disclosed that different sigma receptor subtypes--or even binding pockets on the same receptor molecule--can act in opposite ways to either promote or suppress apoptosis (cell death). Given that a number of sigma ligands bind to both sigma-1 and sigma-2 sites (that act in opposition to regulate cell death), the balance of their functional activities ...
Ocular lens tissue mechanics: Understanding the mechanics of lens accommodation (ability of the eye dynamically to focus near to far, or far to near) can assist in the diagnosis of early presbyopia as well as in the development of new potential clinical treatments and intraocular lens (IOL) design and implantation strategies. Related to the mechanism of focusing, presbyopia is an ocular disease that stems from age-related loss of lens accommodation leading to loss of focusing range and near vision. This is attributed to changes in ciliary muscle function, as well as changes in the elastic and deformable properties of the lens substance and the lens capsule. The precise relationship of these changes, however, is not well described. During cataract surgery, the process of removing a circular portion latitudinally of the anterior lens capsule can lead to tearing of the capsule longitudinally, propagating to the posterior capsule and loss of the full lens and zonules. A fundamental understanding of ...
Cataracts are a degenerative change of the lens, resulting in an opacity and interference with optical clarity and vision. Cataracts are the most common cause of blindness in dogs. Surgical removal of the cataract and replacement with an artificial intraocular lens implant (IOL) restores vision. The leading complication of cataract surgery in dogs and humans is posterior capsular opacification (PCO), a hazy opacity of the lens capsule developing post-operatively that results in diminished vision. This is treated with laser surgery in humans which cannot be performed in dogs. Therefore, an alternative method for preventing or decreasing PCO must be found. A capsular tension ring (CTR) is a device that can be placed within the lens capsule, with the IOL, at the time of cataract surgery. Previous studies in humans have shown that CTRs significantly decrease PCO formation. We hypothesize that CTRs will significantly diminish PCO formation in canine lenses using an ex vivo model and in clinical canine
Eloise Mikkonen from the University of Tampere, Finland, is part of a collaborative project investigating a connection between herpes simplex virus and Alzheimers disease. Thanks to a Travelling Fellowship from DMM, she visited her collaborators in Umeå University, Sweden, and the team have now published their work in DMM. Read more on her story here.. Where could your research take you? The deadline to apply for the current round of Travelling Fellowships is 23 February 2018. Apply now!. Did you know that DMM also offers conference travel grants? Apply by 9 March 2018. Find out more here.. ...
Cataract surgery is a very common procedure with low risks involved. Less than a single percent of patients will suffer from any serious complications that will necessitate further surgeries. If complications do arise, these are, more often than not, successfully treated through additional procedures.. While it is possible that your vision may get worse or that permanent damage may occur after the cataract surgery, these cases are extremely rare. Still, a comprehensive consultation with your eye doctor should be done so that you will be fully informed of all the possible risks.. Posterior Capsule Opacification. The most common risk that a cataract patient may encounter after surgery is the development of a condition called posterior capsule opacification, or PCO. In this condition, a portion of the capsule of your lens may thicken and lead to a cloudy vision. While some may mistake this as a sign of the cataract returning, it is actually cells growing at the back of the artificial lens.. This is ...
TY - JOUR. T1 - Traumatic corneal laceration with associated lens capsule disruption. T2 - A retrospective study of 77 clinical cases from 1999 to 2009. AU - Paulsen, Michael E.. AU - Kass, Philip H. PY - 2012/11. Y1 - 2012/11. N2 - Objective Examine prognostic factors that may indicate when surgical lens removal is indicated to prevent vision-threatening complications in patients presented following traumatic perforating corneal laceration with associated lens capsule disruption. Procedures Seventy-seven patients (10 cats and 67 dogs) were evaluated with this injury; of these, 47 were presented acutely and treated surgically and/or medically. Successful outcome was defined as functional vision in the treated eye. Results The 47 patients with acute injuries were divided into 3 treatment groups A-C for comparison; A - corneal repair/lens removal (n = 15), B - corneal repair/no lens removal (n = 9), C - medical management (n = 23). Groups A and B showed a significantly greater rate of vision loss ...
The present invention relates to an intraocular lens, including a flexible capsule adapted to be inserted into the natural lens capsular bag. A polymerized portion is positioned within the flexible capsule, and an unpolymerized material is located within the flexible capsule, and has loose monomers and a polymerization initiator so that the unpolymerized material changes its volume when exposed to an energy source.
Three variants on the human in vitro capsular bag model were employed. The first was used to assess an open bag IOL (Anew Zephyr™); this involved using the bag-zonular-ciliary body complex isolated from human donor eyes and attached to a silicone ring. A capsulorhexis and lens extraction were performed, and an Alcon Acrysof IOL or Anew Zephyr™ IOL implanted in to the suspended capsular bags. To assess cell growth in different medium volumes (1.5 versus 6mL) we employed a non-suspended human capsular bag model in which the bag is isolated from the ciliary body and secured to a culture dish with pins. We further adapted the capsular bag system, such that radial incisions were made in the anterior capsule, which was then folded back and secured to a dish (a fully open bag model). Cell growth was observed by phase-contrast microscopy and quantified using ImageJ software. Growth factor levels were detected by ELISA ...
A collection of 33 Extra Large, Full-Color plates for chair-side consultation of all subjects of eye care. By Ophthalmic Artist Stephen F. Gordon. Contains full color, full page plates of: A. Normal Eye B. Normal Orbit 1. Cataract 2. Phacoemulsification 3. Lens Implantation 4. Intraocular Lens (Posterior) 5. Laser Posterior Capsulotomy 6. Extracapsular Extraction 7. Astigmatism 8. Nearsighted (Myopia) 9. Farsighted (Hyperopia) 10. Presbyopia 11. Corneal Transplant 12. RK 13. PRK 14. LASIK for Myopia 15. LASIK for Hyperopia 16. Astigmatic Keratotomy 17. Normal Fundus 18. PVD-Floaters-Traction 19. Retinal Detachment 20. Scleral Buckle 21. Macular Degeneration 22. Diabetic Retinopathy 23. Panretinal Photocoagulation 24. Glaucoma 25. Optic Disc 26. Laser Iridotomy 27. Laser Trabeculoplasty 28. Trabeculectomy 29. Lacrimal and Lid 30. Normal Lid/Blepharitis/Chalazion 31. Muscles. ||||| TO ORDER THIS BOOK and have it SHIPPED to you, click the Buy in Print button below. |||||
OCT Application Before and After Cataract Surgery. By Xiaogang Wang, Jing Dong, Suhua Zhang and Bin Sun. Optical coherence tomography (OCT), especially anterior segment OCT (AS-OCT), plays an important role in ophthalmology. With the technology evolving from time-domain to spectral-domain, more and more detailed ocular information has become available. Anterior segment OCT provides particularly useful information for cataract surgeons. This chapter focuses mainly on AS-OCT evaluation of eyes before and after cataract surgery. Four aspects including: (1) anterior lens capsule and lens epithelium evaluation using spectral-domain OCT (SD-OCT); (2) investigation of clear corneal incision in femtosecond laser assisted cataract surgery using SD-OCT; (3) capsular block syndrome evaluation before and after treatment using SD-OCT; (4) IOL power calculation in post-myopic excimer laser eyes using SD-OCT, will be discussed in this chapter.. Part of the book: OCT ...
Is your vision blurry, especially at night or in very bright light? It could be an early symptom of cataracts. A cataract is a clouding of the lens of the eye that interferes with clear vision. Unlike a healthy, transparent lens, which focuses light rays precisely onto the retina, a lens clouded by a cataract loses its ability to focus light rays. The light that reaches the retina is scattered and diffuse, causing blurry vision. The amount of vision impairment depends on the size and density of the cataract and where it is located in the lens: the nucleus, cortex, or posterior lens capsule. A cataract in the periphery of the cortex, for example, has little effect on vision because it does not impede the passage of light through the center of the lens. On the other hand, a dense nuclear cataract causes severe blurring, interfering primarily with distant vision (at first). A cataract that develops in the posterior capsule has a greater effect on near vision and also causes sensitivity to glare. ...
Posterior Capsule Opacity is NOT a result of a complication during or from your cataract surgery. It is however an unavoidable after effect of cataract surgery. It is easily treated and the vision in most cases is restored; as long as there is no other associated ophthalmic pathology.. The natural lens in the eye that forms a cloudy image known as a cataract sits inside what is called a capsule . The capsule is elastic in form and shrinks tightly around the lens. During cataract surgery the lens is removed through a small incision in the front of the lens capsule and vacuumed out and the new intraocular lens is put in its place. The capsule then wraps around it neatly, avoiding the need for sutures. Inside the lens are epithelial cells that continue to grow at a minute rate from the time our eyes form as a foetus. During cataract surgery these cells are removed with the cloudy lens, however it is unavoidable that some of the microscopic cells may remain. It is these epithelial cells that form ...
Six rabbits underwent phacoemulsification with bilater implantation of an IOL. Postoperative power adjustment was performed using the femtosecond laser 2 weeks following implantation, in one eye. The animals were then followed clinically with slit lamp examination for an additional 4 weeks. The rabbits were then euthanized and the globes were enucleated. The globes were bisected coronally and gross examination and photographs from the posterior aspect were performed to assess anterior capsular opacification and fibrosis as well as posterior capsular opacification. After IOL explantation for power measurements, the globes were sectioned and processed for light microscopy following H&E staining ...
The most common surgery in the world, cataract surgery numbers 3 million yearly in the U.S. alone. Serious complications like: retinal detachment, corneal edema, cornea transplant will claim around 27,000. Within two years, 30%-50% of the 3 million will develop posterior lens capsule cloudiness needing laser treatment with more possible complications, including increased eye pressure. In one ALTERNATIVE cataract treatment, 90% of senile cataract cases improved in visual acuity without surgery. … [Read more...] about Removing Your Own Cataracts! by Julia M Busch ...
Posterior Capsule Opacification After Implantation of a Hydrophilic Acrylic Intraocular Lens (IOL) With Double Square Edge and a Hydrophobic Acrylic IOL With Square Posterior Edge (2007 ...
Academic Journals Database is a universal index of periodical literature covering basic research from all fields of knowledge, and is particularly strong in medical research, humanities and social sciences. Full-text from most of the articles is available. Academic Journals Database contains complete bibliographic citations, precise indexing, and informative abstracts for papers from a wide range of periodicals.
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Cataract surgery is one of the most common surgical procedures performed in the United States, and it has one of the highest success rates of any surgery. However, there are cases after cataract surgery where the patient is still experiencing cloudy vision. This may develop weeks or even months after successful surgery.. This cloudiness is not uncommon, and it can be corrected using a procedure called Posterior Capsulotomy.. The lens of your eye has a cellophane-like outer lining called the capsule. During cataract surgery, the natural lens in the eye is removed, but great care is taken to keep the capsule in place to hold the replacement artificial (intraocular) lens.. Sometimes after surgery, the posterior capsule (located behind the implanted intraocular lens) can become cloudy, causing some loss of vision. When this happens, your ophthalmologist performs a Posterior Capsulotomy to reduce the obstruction.. The procedure is often called a YAG Laser Treatment, after the name of the instrument ...
Safety study to examine the use of mitomycin-C, distilled water and triton-X for sealed irrigation of the capsular bag to prevent posterior capsule opacification in ...
In this 1-Minute Video, Dr. Arsham Sheybani performs phacoemulsification in a patient with posterior capsule puncture after intravitreal injection.
The developing lens is a powerful system for the study of tissue interactions and also the target of the medically important ocular disease cataract, a lens opacity that affects over 25 million individuals and is the leading cause of blindness worldwide (Asbell et al., 2005; Hejtmancik, 2008). The mature lens consists of two polarized cell types: a monolayer of lens epithelial (LE) cells and a mass of elongated and aligned lens fiber (LF) cells. The entire structure is covered by a lens capsule, a thick basement membrane secreted by LE and early LF cells in a polarized manner (Wederell and de longh, 2006). During development, the lens originates from a thickening of the head ectoderm that invaginates to form the lens pit, and then detaches to form the lens vesicle. Cells from the anterior lens vesicle differentiate into epithelial cells, while cells from the posterior lens vesicle elongate to form primary fiber cells. In later embryogenesis, LE cells continuously proliferate and differentiate ...
The results of this study showed a statistical similarity for washout times between groups. However, comparedwith brimonidine, a trend existed to a slightly longer mean ALTHOUGH VARIOUS RETINAL COMPLICATIONS, SUCH as aphakic/pseudophakic cystoid macular edema,1 pe- washout period, and among individuals, washout periods ripheral retinal breaks, and retinal detachment,2,3 have were often greater than 1 month for latanoprost. Both been well described after cataract surgery, and they are medications demonstrated a wide variation of the washout thought to be increased by intraoperative breach of the posterior capsule and late posterior capsulotomy for pseu- This study suggests that after discontinuing latanoprost dophakic posterior capsular opacification,1-3 the underly- or brimonidine, a wide variation exists in washout times ing mechanisms remain unclear.1-3 Full-thickness macular among individuals, with latanoprost demonstrating a trend hole formation has also been described after uncompli- cated ...
Ideally, the capsulorhexis diameter should be slightly smaller than the optic diameter so that we can achieve 360° overlap. But what if it doesnt? Well, it turns out that it is not that big of an issue because the capsule shrink-wraps in the post-op period and it makes the capsulorhexis diameter about 10% smaller --…
Researchers began by looking at the properties of lens epithelial stem cells (LECs). These are cells that regenerate replacement lens cells as a person ages, but this process slows as a person gets older. They wanted to see which genes controlled how they developed into fully formed lens cells. After establishing that LECs had the potential to regenerate lenses, they started developing their surgical technique on young animals - firstly using rabbits, then macaque monkeys. When they had shown that both animals could regenerate complete, working lenses from the LECs that remained in a largely intact lens capsule, the researchers carried out the surgery on 12 children (24 eyes). They then compared the results to 25 children (50 eyes) treated with the conventional method. The surgery was carried out as a randomised controlled trial, with children randomly allocated to either the new operation or the standard method. The new operation involved making much smaller cuts in the lens capsule (about 1 to ...
Purpose: We categorize weak zonule during capsulorhexis. Design: Retrospective interventional case series. Methods: The study examined 5447 consecutive eyes of 3527 c..
The clear cell histologic subtype of stage I ovarian cancer is associated with a disproportionately high risk for capsule rupture during surgery compared with other histologies.
The lens capsule is a component of the globe of the eye. It is a clear, membrane-like structure that is quite elastic, a quality that keeps it under constant tension. As a result, the lens naturally tends towards a rounder or more globular configuration, a shape it must assume for the eye to focus at a near distance.. ...
Cataract surgery is performed under a full general anaesthetic and a muscle relaxant is given so that the eye comes into the correct position for the operation. This means that a ventilator needs to be used to inflate the chest during the procedure. We monitor your dog very carefully throughout the surgery using very modern sensitive equipment and the staff involved are specially trained in the procedure. This helps to reduce the risks of the anaesthetic to a very low level.. The operation is very delicate and involves the use of an operating microscope and tiny instruments. Two small cuts are made in the window of the eye (the cornea), near where the coloured part (the iris) joins the white part.. The lens is just behind the iris and lies in a delicate bag of tissue called the capsule. After the eye has been filled with a special gel called a viscoelastic, some of the lens capsule is taken out. The gel which is used helps to inflate the eye and protect the structures inside it from the effects ...
The PCCC hosted its Kickoff Meeting on March 14-15, 2013 in Fulda. All projects were presented and discussed during the meeting and the network of collaborative research activities was further developed, also involving the associated industry partners. Critical feedback from the members of the Advisory Board contributed to shaping the consortium s research activities ...
A remotely operable ocular surgical cutting instrument (10), useful, for instance as a knife for a capsulotomy procedure, has a two portion main body (12) with one portion (16) oriented at an angle with respect to the other (14). A turning unit (20) extends through the main instrument body (12), and, to constitute a capsulotomy knife, a cutting blade (22) is mounted on the turning unit (20) at one end of the body (12). During operation, the orientation of cutting edge of the blade (22) with respect to the instrument body (12) is determined by manipulation of the opposite end of the turning unit at the other end of the instrument body (12).
De handige preloaded tension ring is ontwikkeld door Morcher. Het geheel is disposable en erg prettig in het gebruik. Dit innovatieve product ligt standaard bij ons op voorraad.. Let op, Rockmed heeft alleen de 14R op voorraad.. ...
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A three-piece rock wrecking crew from Melbourne, Kingswood trace a direct line from legends like AC/DC, the Easy Beats and Cold Chisel through to the modern rock of today.
Copper deposition in peripheral Descemet membrane (Kayser-Fleischer ring) and anterior capsule of crystalline lens ( Sunflower ...
A corelysis is a surgical detachment of adhesions of the iris to the capsule of the crystalline lens or cornea. A coremorphosis ... A cataract is an opacification or cloudiness of the eye's crystalline lens due to aging, disease, or trauma that typically ... If visual loss is significant, surgical removal of the lens may be warranted, with lost optical power usually replaced with a ... Refractive surgery aims to correct errors of refraction in the eye, reducing or eliminating the need for corrective lenses. ...
... is a rare congenital anomaly of the eye characterized by a conical protrusion on the crystalline lens capsule and the ... sharply demarcated conical projection of the lens capsule and cortex, usually axial in localization. In an early stage, retro- ... This phenomenon is due to the different refraction in the central and the peripheral area of the lens. Ultrasonography also can ... It produces a decrease in visual acuity and irregular refraction that cannot be corrected by either spectacle or contact lenses ...
... lens capsule, crystalline MeSH A09.371.509.225 - lens cortex, crystalline MeSH A09.371.509.670 - lens nucleus, crystalline MeSH ...
... the lens capsule, the lens epithelium, and the lens fibers. The lens capsule forms the outermost layer of the lens and the lens ... "equator of the crystalline lens - definition of equator of the crystalline lens in the Medical dictionary - by the Free Online ... The lens epithelium, located in the anterior portion of the lens between the lens capsule and the lens fibers, is a simple ... The lens capsule is a smooth, transparent basement membrane that completely surrounds the lens. The capsule is elastic and is ...
Phakia is the presence of the natural crystalline lenses. Phakic IOL (PIOL) refers to an intraocular lens implanted without ... Accommodative intraocular lenses may also have a slightly higher risk of developing posterior capsule opacification (PCO), ... More commonly IOLs are implanted via Clear Lens Extraction And Replacement (CLEAR) surgery. During CLEAR, the crystalline lens ... the human crystalline lens in order to attempt to protect the retina after cataract extraction of the natural crystalline lens ...
... a surgical technique in which the crystalline lens material is removed but the surrounding capsule which contained it is left ... The capsule of the lens was pierced with a smaller cut than in conventional cataract surgery - just 1-1.5 mm - and drained of ... The capsule was otherwise left intact as this is lined with lens epithelial stem cells, which then reproduced to regenerate the ... The new lens was similar in structure to the structure but its shape might be irregular. Filling the capsule during ...
The newts had part of their front limbs amputated and their crystalline lenses removed to study the possible rate of human ... A barometric pressure recorder mounted in the primate capsule was used to correct and normalise the implanted pressure sensor ... Monkeys were housed in Soviet biosatellite capsules, as for the Kosmos 1514 mission. United States hardware developed for the ...
... be safely and painlessly corrected using a laser device to make small holes in the posterior lens capsule of the crystalline. ... The Crystalens is on struts and is implanted in the eye's lens capsule, and its design allows the lens' focusing muscles to ... Cataract surgery, also called lens replacement surgery, is the removal of the natural lens of the eye (also called "crystalline ... Intracapsular cataract extraction (ICCE) involves the removal of the lens and the surrounding lens capsule in one piece. The ...
The lens is biconvex, and the body of the stemma has a vitreous or crystalline core. ... Moth larva about to moult; the new stemmata are visible behind the old head capsule ... The eyes of humans and large animals, and camera lenses are classed as "simple" because in both cases a single lens collects ... A dorsal ocellus consists of a lens element (cornea) and a layer of photoreceptors (rod cells). The ocellar lens may be ...
The zonules attach to the lens capsule 2mm anterior and 1 mm posterior to the equator, and arise from the pars plana region of ... that connects the ciliary body with the crystalline lens of the eye. These fibers are sometimes collectively referred to as the ... The zonules insert around the outer margin of the lens (equator), both anteriorly and posteriorly. Securing the lens to the ... "Surface ultrastructure of the human lens capsule and zonular attachments". Investigative Ophthalmology. 15 (1): 36-40. PMID ...
Since the objective lenses of microscopes focus the laser beam to several micrometres in diameter, the resulting photon flux is ... Transmission Raman - Allows probing of a significant bulk of a turbid material, such as powders, capsules, living tissue, etc. ... "Controlled Vapor Phase Growth of Single Crystalline, Two-Dimensional Ga Se Crystals with High Photoresponse". Scientific ... Electromagnetic radiation from the illuminated spot is collected with a lens and sent through a monochromator. Elastic ...
... is a displacement or malposition of the eye's crystalline lens from its normal location. A partial dislocation ... in which lens comes out of the eyeball and becomes trapped under the Tenon's capsule or conjunctiva [6] A nonsurgical ... of a lens is termed lens subluxation or subluxated lens; a complete dislocation of a lens is termed lens luxation or luxated ... Lens subluxation[edit]. Lens subluxation is also seen in dogs and is characterized by a partial displacement of the lens. It ...
... causing the central surfaces of the crystalline lens to steepen, the central thickness of the lens to increase (anterior- ... The anterior capsule and the zonule form a trampoline shape or hammock shaped surface that is totally reproducible depending on ... It is in this lens shape that the mechanically reproducible state of a steep radius of curvature in the center of the lens with ... The increased equatorial zonular tension keeps the lens stable and flattens the peripheral lens surface during accommodation. ...
They form photosensitizers in the crystalline lens, which has implications for cataract development. Reduced muscle function is ... Large AGE proteins unable to enter the Bowman's capsule are capable of binding to receptors on endothelial and mesangial cells ... lens and renal cortex of diabetic rats. The inhibition of AGE formation reduced the extent of nephropathy in diabetic rats. ... "Advanced Glycation Endproducts Induce Photocrosslinking and Oxidation of Bovine Lens Proteins Through Type-I Mechanism". ...
This extreme, localized heat causes the quartz to change from its vitreous form into a weaker, crystalline form that leaks gas ... Halogen lamps' thick glass lenses are safe to use inside high humidity reptile enclosures. Banks of powerful tubular halogen ... and the bulb may be handled without damaging it surroundings are protected from possible shattering of the inner capsule the ...
The UPW forms a puddle between the lens and the wafer, improving NA, and the UPW must be extremely pure. POU filtration is used ... Certain tools may use a fixed filter housing with replaceable filters, whereas other tools may use disposable filter capsules ... and crystalline silicon photovoltaics; the cleanliness requirements in the semiconductor industry, however, are currently the ... Another POU UPW application for lithography is the immersion water used at the lens/wafer interface for 193 nm immersion ...
Ceramic materials may have a crystalline or partly crystalline structure, with long-range order on atomic scale. Glass ceramics ... laser amplifiers and lenses, hosts for solid-state lasers and optical window materials for gas lasers, and infrared (IR) heat ... "Fluorescent Guest Molecules Report Ordered Inner Phase of Host Capsules in Solution". Science. 309 (5743): 2037-9. Bibcode: ... At a certain point (~70% crystalline) the glass-ceramic has a net TEC near zero. This type of glass-ceramic exhibits excellent ...
Crystalline Suspension: With crystalline suspensions the crystalline size governs the rate of absorption and therefore the ... Progesterone in the form of oral capsules; vaginal capsules, tablets/inserts, and gels; and intramuscular oil have widespread ... www.indufar.com.py/files/shares/prospectos/400000154.pdf Lens J, Overbeek GA, Polderman J (1949). "The effect of sex hormones ... Progesterone is available in a variety of different forms, including oral capsules; sublingual tablets; vaginal capsules, ...
Immersion lithography places a layer of pure water between the projection lens and the wafer. Any contaminant within the water ... Spiegelman, J. "Silicon Dioxide Layer Key to High Efficiency Crystalline Solar Cells". Technical White Paper, 2010. Deal, B. E ... The boiling action of water creates microdroplets, which act as liquid capsules that entrain particles and molecular ... Jianhua Zhao, "Production Technologies For High Efficiency Crystalline Silicon Solar Cells", CEEG Nanjing PV-Tech Co. Ltd, ...
Glasses (non-crystalline ceramics) also are used widely as host materials for lasers. Relative to crystalline lasers, they ... The use of evacuated glass capsules to perform HIP treatment allowed samples that showed open porosity after vacuum sintering ... laser amplifiers and lenses, hosts for solid-state lasers and optical window materials for gas lasers, and infrared (IR) heat ... the size of the crystalline grains is determined largely by the size of the crystalline particles present in the raw material ...
The eye changes focus by shifting the position of the entire lens with respect to the retina, instead of reshaping the lens as ... The egg case is produced through a complex capsule of the female accessory genital glands and the ink bag. On occasion, a large ... They reflect light using plates of crystalline chemochromes made from guanine. When illuminated, they reflect iridescent colors ... Leucophores, usually located deeper in the skin than iridophores, are also structural reflectors using crystalline purines, ...
The zygote grows into the ascus, an elongated tube-shaped or cylinder-shaped capsule. Meiosis then gives rise to four haploid ... The Woronin bodies are spherical, hexagonal, or rectangular membrane bound structures with a crystalline protein matrix. ...
Orange spider egg sac hanging from ceiling Gasteracantha mammosa spiderlings next to their eggs capsule Wolf spider carrying ... 325-349 Vollrath, F. & Knight, D.P. (2001). "Liquid crystalline spinning of spider silk". Nature. 410 (6828): 541-48. Bibcode: ... This acuity is achieved by a telephotographic series of lenses, a four-layer retina, and the ability to swivel the eyes and ...
Scientists at Cornell University use a specialised lens to entirely cloak an object from view for 40 trillionths of a second by ... NBC News) (AIDS2012) Ageing termite workers are discovered to use a toxic crystalline structure to "self-destruct", spraying ... jumping from a pressurized capsule 24 miles (39 km) above Roswell, New Mexico. Baumgartner became the first human to break the ... Science Daily) A Belgian team develops a curved LCD contact lens display. Researchers say the prototype could be used in ...
The patent application[94][95] claimed the final form of Gleevec (the beta crystalline form of imatinib mesylate).[96]:3 In ... In 1980, Ciba-Geigy set up the company, Ciba Vision, to enter the contact lens market.[24] In 1992 Ciba-Geigy agreed to pay New ... "Focalin XR (dexmethylphenidate hydrochloride) extended-release capsules CII". Warning Letters. US Food and Drug Administration ... Pharmaceuticals, generic drugs, over-the-counter drugs, vaccines, diagnostics, contact lenses, animal health (list...). ...
capsule A dry fruit formed from two of more united carpels and dehiscing when ripe (usually by splitting into pieces or opening ... lenticular 1. lens-shaped. 2. covered in lenticels. lepidote covered with small scales. leprose powdery liana a woody climbing ... epicuticular wax A layer of crystalline or amorphous wax deposited on the surface of the cuticle. epidermis An organ's ... lenticel Typically lenticular (lens-shaped) porous tissue in bark with large intercellular spaces that allows direct exchange ...
A crystalline Green Lantern. Voice Actor: Alexander Polinsky He, Sinestro, and Guy Gardner call upon Batman to space to help ... Batman does not want to leave Kamandi and Canus to the mercy of the ratmen, and instead leaves a time-capsule in the Statue of ... Upon discovering Ray Palmer's former home and research, he modified the lens in order to grow to the size of a human. With this ... Atomic-Man is a criminal that wears special lenses that enable him to focus his eye beams that can transmute one matter to ...
The nictitating membrane also covers the eye and acts as a contact lens in many aquatic birds. With the exception of pigeons ... They differ from Pacinian corpuscles in being smaller and more elongated, in having thinner and more closely placed capsules ... without which the crystalline structure would be too brittle to keep its form; the organic matrix is thought to have a role in ...
Crystalline. On-line free medical diagnosis assistant. Ranked list of possible diseases from either several symptoms or a full ... Lens Capsule, Crystalline. The thin noncellular outer covering of the CRYSTALLINE LENS composed mainly of collagen type iv and ...
What is crystalline capsule? Meaning of crystalline capsule medical term. What does crystalline capsule mean? ... Looking for online definition of crystalline capsule in the Medical Dictionary? crystalline capsule explanation free. ... capsule of lens. (redirected from crystalline capsule) capsule. [kap´sul, kap´sūl] 1. an enclosing structure, as a soluble ... Tenons capsule the connective tissue enveloping the posterior eyeball.. capsule of lens. [TA] the capsule enclosing the lens ...
Posterior capsule opacification developed in all experimental animals within 6 weeks of the operat … ... The lenses of New Zealand White and Flemish Giant rabbits were removed using five techniques representative of the different ... The lenses of New Zealand White and Flemish Giant rabbits were removed using five techniques representative of the different ... Posterior capsule opacification: experimental analyses Ophthalmic Res. 1985;17(2):75-84. doi: 10.1159/000265354. ...
... pseudoexfoliation syndrome has an increased intraoperative posterior capsule complication rate that increases as the level of ... Lens Capsule, Crystalline / pathology* * Lens Diseases / etiology* * Male * Middle Aged * Risk Factors ... Background: To evaluate rates of intraoperative posterior capsule complications in manual small-incision cataract surgery of ... Preoperative data collected were cataract maturity level, best corrected visual acuity, and intraoperative posterior capsule ...
... lensing explanation free. What is lensing? Meaning of lensing medical term. What does lensing mean? ... Looking for online definition of lensing in the Medical Dictionary? ... lens capsule See capsule; crystalline lens.. lens carrier See lenticular lens; bioptic telescope.. cast-moulding contact lens A ... Syn. convex lens; plus lens; positive lens.. corrected lens See best-form lens.. lens cortex See crystalline lens.. cosmetic ...
A conduit through which a drug is introduced penetrates at least the outer lens capsule for drug delivery. When withdrawn, the ... A method of delivering a drug or other compound to the lens of the eye. ... wherein the conduit penetrates at least one of a lens capsule, a lens subcapsule epithelium, a lens cortex, or a lens nucleus. ... The lens capsule 14, which includes an anterior capsule portion 22 and a posterior capsule portion 24, is a clear, membrane- ...
Diseases of crystalline lens and capsule. I. On the growth of the crystalline lens. - Trans. Ophthalmic Soc. UK 3: 79-99. ... For individuals with two eye lenses we used the lens with the largest mass in our analyses because the other lens likely had a ... The mammalian eye lens continues to grow until death and hence the dry mass of the eye lens has commonly been used to estimate ... In each of the five models, γ is the asymptotic eye lens dry mass, α is the natal eye lens dry mass (except for the Lord model ...
Posterior capsule rupture , 10% occurrence rate [ Time Frame: Time of Surgery ]. *Less than 5% of eyes should lose more than ... of Laser Treatment of the Crystalline Lens in Subjects Having Elected to Undergo Lens Extraction and Intraocular Lens ... Laser Treatment of the Crystalline Lens. The safety and scientific validity of this study is the responsibility of the study ... Lens removal a. Ease of irrigation / aspiration (time) b. Reduced ultrasound phacoemulsification [ Time Frame: Time of surgery ...
Copper deposition in peripheral Descemet membrane (Kayser-Fleischer ring) and anterior capsule of crystalline lens ( Sunflower ...
The change, during accommodation, of stress on the surface of the anterior lens capsule (ALS) was determined by employing high- ... Conclusions: The stress on the anterior lens capsule is increased during in vivo human accommodation. This observation is ... Purpose: To determine the qualitative change in stress on the lens capsule during in vivo human accommodation. ... The Stress on the Anterior Lens Surface During Human in vivo Accommodation ...
... be positioned in the posterior chamber of the eye such that the optical portion is spaced anteriorly from the crystalline lens ... An alternative intraocular lens includes an optical portion having a peripheral optic zone and an inner non-optic zone. Methods ... The intraocular lens may be deformed before or during insertion in an eye of a patient, and may ... In alternative embodiments, an intraocular or intracorneal lens of the invention may be inserted in the anterior chamber, or ...
... linear absorption promotes and linear absorption promote generates to revise eye inner tissue and synthetic intraocular lens. ... lens capsule, crystalline lens and synthetic intraocular lenss implant composition, select.Described pattern can be configured ... lens capsule, crystalline lens and synthetic intraocular lenss implant composition, select. InstituteThe pattern of stating ... In addition, owing to ining contrast to corneal incision and lens capsule, crystalline lens regulate required precision and ...
A corelysis is a surgical detachment of adhesions of the iris to the capsule of the crystalline lens or cornea.[14] ... Whereas a capsulotomy is the creation of an opening in the lens capsule, a capsulectomy is the acutal removal of lens capsule ... involves the removal of the lens and the surrounding lens capsule in one piece. The lens is then replaced with an artificial ... Extracapsular cataract extraction involves the removal of the lens while the elastic lens capsule is left partially intact to ...
A cataract is an opacity or clouding that develops in the crystalline lens of the eye or in its capsule. ...
Smith P. Diseases of crystalline lens and capsule. 1. On the growth of the crystalline lens. Trans Ophthalmol Soc UK. 1883; 3: ... Changes in crystalline lens radii of curvature and lens tilt and decentration during dynamic accommodation in rhesus monkeys ... Contribution of the crystalline lens gradient refractive index to the accommodation amplitude in non-human primates: In vitro ... Growth patterns of fresh human crystalline lenses measured by in vitro photographic biometry. J Anat. 2005; 206: 575-580. ...
... cataracts appeared in the OCT images as hyperreflective that grew next to the posterior capsule of the crystalline lens (Fig. 4 ... part of the crystalline lens. Although the anterior segment of the crystalline lens (C, G) seems normal, the observation of the ... part of the crystalline lens. Although the anterior segment of the crystalline lens (C, G) seems normal, the observation of the ... part of the crystalline lens. Although the anterior segment of the crystalline lens (C, G) seems normal, the observation of the ...
The rests of a forward capsule were densely connected with a back capsule of a crystalline lens. Visual acuity before operation ... The method of klipping deployed IOL on a back capsule of a crystalline lens allows to reach good and stable centration of ... The technics of operation consisted in formation in the centre of a back capsule of a crystalline lens of an aperture, diameter ... The purpose - to study efficiency of elimination of decentred IOL to a crystalline lens bag. Setting: The Samara State Medical ...
Figure 3. Layers of the lens. Upper section is through the anterior lens capsule showing lens epithelial cells, lec, and lens ... Crystalline Lens and Cataract by Joah F. Aliancy and Nick Mamalis. Crystalline Lens and Cataract ... Crystalline Lens and Cataract by Joah F. Aliancy and Nick Mamalis. *Intraocular Lenses for Cataract Surgery by Jason Nguyen and ... The lens is composed of 4 structures: capsule, epithelium, cortex and nucleus (Fig. 3). The capsule is the basement membrane ...
... we touch the crystalline lens capsule; W: cutting through the capsule (outer ring) and touching the inner lens surface; X: ... capsule (outer ring) and inner lens (center). Fiber structure is suggested in the inner lens tissue. ... Illumination: continuous 300 W Xenon arc lamp with multimode fiber and (L1) microscope objective as entry lens (air, 10×, 0.25 ... achromatic doublet lens (75 cm focal length); Ref: reference mirror (9% reflectivity); PZT: piezoelectric stage actuator; ...
The partial or complete loss of transparency by the crystalline lens, or its capsule, results in a common condition known as ... Accommodation of the eye refers to the physiological act of adjusting crystalline lens elements to alter the refractive power ... Removal of the opaque lens during cataract surgery, with subsequent replacement by a plastic lens (intraocular lens implants), ... Light scattering and absorption by elements in the crystalline lens contributes to a further loss of sensitivity in the far ...
A corelysis is a surgical detachment of adhesions of the iris to the capsule of the crystalline lens or cornea. A coremorphosis ... A cataract is an opacification or cloudiness of the eyes crystalline lens due to aging, disease, or trauma that typically ... If visual loss is significant, surgical removal of the lens may be warranted, with lost optical power usually replaced with a ... Refractive surgery aims to correct errors of refraction in the eye, reducing or eliminating the need for corrective lenses. ...
... shallower anterior chamber depth and thicker human lens. In pseudophakic eyes, iris conicity is significantly lower, indicating ... thicker human lens and higher corneal power in multivariable analysis, while older age was related to a flatter iris conicity. ... geometrical parameter may be the distance between the iris pigment epithelium and the anterior capsule of the crystalline lens ... Please observe the different light reflexes by the artificial intraocular lens and the crystalline lens. The iris is flat in ...
An opacity of the crystalline lens, or of its capsule, which prevents the passage of the rays of light and impairs or destroys ... The capsule of the patients natural lens is left in place behind the implanted lens which increases the success and safety of ... This is addressed by using a YAG laser to form a hole in the now opaque lens capsule which can now be done with relative safety ... a powerful rigid contact lens. Nowadays the extracted lens is replaced by an implanted artificial lens of a similar effectivity ...
... contact lenses) Corneal refractive procedures (ie, radial keratotomy [RK], automated lamellar keratoplasty [ALK], ... photorefractive keratoplasty [PRK], laser-assisted in situ keratomileusis [LASIK]) Intraocular procedures (ie, clear lens ... or even the crystalline lens. An intermittent or a continuous touch with the anterior lens capsule can produce lens ... The increasing volume of the crystalline lens with age encroaches on the posterior chamber volume. The crystalline lens volume ...
2010) Crystal deposits on the lens capsules in Bietti crystalline corneoretinal dystrophy associated with a mutation in the ... 2004) Bietti crystalline corneoretinal dystrophy is caused by mutations in the novel gene CYP4V2. Am J Hum Genet 74:817-826. ... Bietti crystalline corneoretinal dystrophy. DoGEX. Discovery of General Endo- and Xenobiotics. ESI. electrospray ionization. GC ... Mutations in the CYP4V2 gene (chromosome 4q35.1) have been found to be related to a rare eye disorder, Bietti crystalline ...
The elastic constants and ultrastructure of the basement membrane of the crystalline lens of the adult cat have been ... The elastic constants and ultrastructural organization of a basement membrane (lens capsule). R. F. Fisher, Jennifer Wakely ... The elastic constants and ultrastructural organization of a basement membrane (lens capsule) ... The elastic constants and ultrastructural organization of a basement membrane (lens capsule). ...
Crystal deposits on the lens capsules in Bietti crystalline corneoretinal dystrophy associated with a mutation in the CYP4V2 ... MalaCards based summary : Bietti Crystalline Corneoretinal Dystrophy, also known as bietti crystalline dystrophy, is related to ... MalaCards integrated aliases for Bietti Crystalline Corneoretinal Dystrophy:. Name: Bietti Crystalline Corneoretinal Dystrophy ... MalaCards organs/tissues related to Bietti Crystalline Corneoretinal Dystrophy:. 38 Retina, Eye, Skin ...
... and in front of the anterior capsule of the human crystalline lens. It offers an intraocular alternative for the correction of ... contact lenses were not worn for at least 2 weeks (rigid and toric contact lenses) or 3 days (soft contact lenses) prior to the ... Clinical Performance of a Phakic Intraocular Lens (IOL). The safety and scientific validity of this study is the responsibility ... Current contact lens wearers need to demonstrate a stable refraction, (± 0.5 D), expressed as MRSE, on two consecutive ...
Figure 1 shows an SOCT tomogram of an anterior part of the crystalline lens and the pupillary margin of the iris. The quality ... Human lens capsule thickness as a function of age and location along the sagittal lens perimeter. Invest Ophthalmol Vis Sci ... Assessment of the lens capsule and estimation of its thickness may also be used to evaluate capsule-related cataract-surgery ... A) En-face image of the iris and lens surface reconstructed from three-dimensional data. (B) Anterior lens capsule thickness ...
The lens is enclosed in a lens capsule and consists of lens cortex, and lens nucleus. The lens capsule is an elastic bag ... The lens cortex is a jelly-like portion of the crystalline lens, composed of a multiplicity of thin lens fibers that form the ... fluid facilitates mobilization of the lens within the lens capsule by causing separation of the lens capsule from the lens ... a synthetic lens material can be injected into the lens capsule 43. This material fills the lens capsule 43 and essentially ...
  • the anterior surface has a cuboidal epithelium, and at the equator the cells elongate to become lens fibers. (thefreedictionary.com)
  • 11 . The method of claim 1 wherein the conduit penetrates at least one of a lens capsule, a lens subcapsule epithelium, a lens cortex, or a lens nucleus. (google.com.au)
  • The lens is composed of 4 structures: capsule, epithelium, cortex and nucleus (Fig. 3). (utah.edu)
  • The capsule is the basement membrane with type VI collagen elaborated by the epithelium layer, and stains positively with periodic acid shiff (PAS) stain. (utah.edu)
  • These elastic fibers originate from the nonpigmented epithelium layer of the ciliary body and articulate with the outer layer of the capsule, the capsular lamellar layer. (utah.edu)
  • It was possible to visualise a separate layer of lens epithelium, to the authors' knowledge the first such visualisation. (bmj.com)
  • Conculsions Ultrahigh-resolution, ultrahigh-speed SOCT based on a femtosecond laser allows two- and three-dimensional evaluation of a capsular bag and lens epithelium. (bmj.com)
  • 53 Bietti crystalline corneoretinal dystrophy is an autosomal recessive retinal dystrophy characterized by numerous tiny glistening yellow-white crystals at the posterior pole of the retina, associated with atrophy of the retinal pigment epithelium (RPE), pigment clumps, and choroidal sclerosis. (malacards.org)
  • Posterior subcapsular catarct where the opacity is at the posterior (back) of the lens due to plaque formation or migration of the lens epithelium to the posterior surface. (healthhype.com)
  • The portion of the crystalline lens surrounding the nucleus and bound anteriorly by the epithelium and posteriorly by the capsule. (harvard.edu)
  • Cells within the central anterior epithelium have been present since lens vesicle formation during embryogenesis. (royalsocietypublishing.org)
  • However, the cells in the peripheral epithelium are capable of migration, cell division and differentiation into lens fibre cells that form the bulk of the lens. (royalsocietypublishing.org)
  • Lens crystallines are altered during cataract formation and are accompanied by morphologic changes in lens capsule, anterior lens epithelium and lens fibers. (vetstream.com)
  • Normal lens is maintained in dehydrated state, depends on energy from lens epithelium and lens fibers. (vetstream.com)
  • Historically, the lens has been viewed as a closed system, in which cells at the periphery of the lens epithelium differentiate into fiber cells. (biomedcentral.com)
  • Then we present the ciliary body as a possible source for lens stem cells, and conclude by comparing the ocular lens with the corneal epithelium. (biomedcentral.com)
  • The germinative zone is a narrow cellular region that rings the lens epithelium toward the periphery of the anterior lens surface. (biomedcentral.com)
  • In the fetal eyes, the BM of the corneal epithelium, the Descemet's membrane (DM) and the Bruch's membrane each had their specific combinations of LM chains and time line of development, whereas the lens capsule and the internal limiting membrane showed constant LM chain patterns. (diva-portal.org)
  • The aim of this study is to locate, describe and evaluate the ultrastructural alterations of the anterior lens capsule's epithelium in patients affected by cataract and to connect them with findings in previous studies. (dentisty.org)
  • The internal capsule carries both afferent and efferent fibers of the cerebral cortex. (thefreedictionary.com)
  • The secondary lens fibers eventually grow to form the adult nucleus with new layers of lens fibers forming the lenticular cortex. (utah.edu)
  • When the clinical examination revealed cortical or subcapsular cataracts, hyperreflective features were visible either in the cortex parallel to the surfaces of the lens or in the posterior pole. (arvojournals.org)
  • Other type of opacities that appeared as hyporeflective localized features were identified in the cortex of the lens. (arvojournals.org)
  • 14. The method recited in Claim 13 wherein introducing the second fluid facilitates mobilization of the lens within the lens capsule by causing separation of the lens capsule from the lens cortex. (google.se)
  • Cortical cataract where changes in the hydration and ionic composition in the cortex of the lens causes an opacity in the edge of the lens. (healthhype.com)
  • Lens Cortex, Crystalline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
  • This graph shows the total number of publications written about "Lens Cortex, Crystalline" by people in Harvard Catalyst Profiles by year, and whether "Lens Cortex, Crystalline" was a major or minor topic of these publication. (harvard.edu)
  • Below are the most recent publications written about "Lens Cortex, Crystalline" by people in Profiles. (harvard.edu)
  • The researchers used intact porcine lenses from five-month-old pigs, intact human lenses obtained from three donors aged 41, 42 and 45 years, and sections of human lens cortex obtained from four donors aged 11, 19, 32, and 34 years were incubated for 72 hours at 7°C in aqueous solutions of green (566 nm) and red (652 nm) fluorescent water soluble cadmium tellurium (CdTe) nanoparticles. (nanowerk.com)
  • Lenticonus (/len·ti·co·nus/ (len″tĭ-ko´nus)) [lens + L. conus, cone] is a rare congenital anomaly of the eye characterized by a conical protrusion on the crystalline lens capsule and the underlying cortex. (wikipedia.org)
  • Biomicroscopically lenticonus is characterized by a transparent, localized, sharply demarcated conical projection of the lens capsule and cortex, usually axial in localization. (wikipedia.org)
  • Rotating Scheimpflug imaging (Pentacam 70700:Oculus, Wetzlar Germany) confirmed the traumatic cataract in the region of the PCT visualized as increased lens density at the cortex-vitreous interface. (bvsalud.org)
  • Preoperative data collected were cataract maturity level, best corrected visual acuity, and intraoperative posterior capsule complications as documented in the surgical report, namely (1) posterior capsule rupture or zonulolysis, or both, and (2) vitreous loss. (nih.gov)
  • The human eye is equipped with a variety of optical components including the cornea, iris, pupil, aqueous and vitreous humors, a variable-focus lens, and the retina (as illustrated in Figure 1). (fsu.edu)
  • In order to reach the retina, light rays focused by the cornea must successively traverse the aqueous humor (in the anterior chamber), the crystalline lens, the gelatinous vitreous body, and the vascular and neuronal layers of the retina before they reach the photosensitive outer segments of the cone and rod cells. (fsu.edu)
  • The large spheroid space in back of the lens (the center of the eyeball) is filled with vitreous humor, a jellylike substance. (thefreedictionary.com)
  • either in the crystalline lens in the vitreous or in the aqueous humours. (intune-media.co.uk)
  • The adult lens is isolated from other tissues and has no innervations or vascular system, receiving all required nutrients from the aqueous and vitreous humours that bathe it. (royalsocietypublishing.org)
  • The diversion of aqueous flow into the posterior segment comes from an abnormal relationship between the ciliary body process, lens, and anterior vitreous. (eyeworld.org)
  • The lens is located behind the iris and in front of the vitreous body. (everydaysight.com)
  • Lens vesicle posterior epithelial cells (pec) elongate to form the primary lens fibers (H&E stain, X10). (utah.edu)
  • The anterior cells become the lens epithelial cells, while the primary lens fibers collectively form the embryonic nucleus. (utah.edu)
  • Subsequently, secondary lens fibers begin to elongate from the lens epithelial cells to form the fetal nucleus during the gestation period and continues to grow multiple layers. (utah.edu)
  • Upper section is through the anterior lens capsule showing lens epithelial cells, lec, and lens fibers, lf. (utah.edu)
  • Our study aimed at exploring the effects of miR-211 on the proliferation and apoptosis of lens epithelial cells in diabetic cataract mice by targetting NAD + -dependent histone deacetylase sirtulin 1 (SIRT1). (portlandpress.com)
  • Lens epithelial cells were classified into the normal, blank, negative control (NC), miR-211 mimics, miR-211 inhibitors, siRNA-SIRT1, and miR-211 inhibitors + siRNA-SIRT1 groups. (portlandpress.com)
  • MiR-211 could promote apoptosis and inhibit proliferation of lens epithelial cells in diabetic cataract mice by targetting SIRT1. (portlandpress.com)
  • Lens epithelial cell apoptosis is a common cellular foundation for the development of non-congenital cataract in human beings and animals [ 8 ]. (portlandpress.com)
  • Former evidence revealed that high glucose concentrations could lead to apoptosis of human lens epithelial cell and inhibit proliferation [ 9 ]. (portlandpress.com)
  • MiRNA has been widely studied for its close association with lens epithelial cells [ 10 - 12 ]. (portlandpress.com)
  • The lens is comprised of tightly packed epithelial cells and lens fibers, enclosed in a thin capsule' Schachar and Pierscionek explain to Nanowerk. (nanowerk.com)
  • The authors created new human immortalized crystalline lens epithelial cells (iHLEC-NY1s) with excellent differentiation potential, and as a result of culturing the cells by static and rotation-floating methods, succeeded in producing a three-dimensional cell structure model (3D-iHLEC-NY1s) which is similar to Soemmering's ring in tissue structure and expression characteristics of αA-crystalline, βB2-crystalline, vimentin proteins. (fujita-hu.ac.jp)
  • In farsightedness ( hyperopia ) the image is focused behind the retina because the refractive power of the lens is too weak or the eyeball axis is too short. (thefreedictionary.com)
  • Nearsightedness ( myopia ) occurs when the refractive power of the lens is too strong or the eyeball is too long, so that the image is focused in front of the retina. (thefreedictionary.com)
  • The normal crystalline lens is transparent, refractive, and provides adequate accommodation (shape change) to transmit and focus light on the retina at various distances. (google.com.au)
  • A cataract is an opacification or cloudiness of the eye's crystalline lens due to aging, disease, or trauma that typically prevents light from forming a clear image on the retina. (wikibooks.org)
  • The lens of the eye is a biconvex, relatively acellular, optically transparent intraocular structure that with the cornea serves to transmit light to the retina with minimal light scattering (Fig. 1a). (utah.edu)
  • We now know that this is the function of the retina, with the lens serving as a conduit of light transmission and focus to the retina. (utah.edu)
  • The lens can change shape with the aid of the ciliary muscles, thereby changing the focal distance to the retina and bringing the image into sharp focus on the retina. (utah.edu)
  • A human eyeball cut in half to show the lens and the passage of light through it from the object ahead to the focus on the retina. (utah.edu)
  • When an object is observed, it is first focused through the convex cornea and lens elements, forming an inverted image on the surface of the retina , a multi-layered membrane that contains millions of light-sensitive cells. (fsu.edu)
  • The cornea removes some of the most damaging ultraviolet wavelengths present in sunlight, thereby further protecting the highly susceptible retina and crystalline lens from damage. (fsu.edu)
  • Our eye's lens is a transparent, crystalline structure that, like glasses, directs incoming light to the back of the eye (the retina). (naturaleyecare.com)
  • Light, focused according to the distance of the object, passes through the lens to the retina where photoreceptor cells in the retina direct the light energy to the optic nerve which, in turn, transmits the information to the brain for interpretation. (naturaleyecare.com)
  • The role of the lens role is to focus light onto the retina. (cat-world.com.au)
  • It then passes through the lens of the eye which bends the light (refraction) to focus it on the back of the retina. (healthhype.com)
  • Normally in the human eye , light passes through the lens and is bent (refraction) so that all beams of light are focused on a single spot on the retina. (healthhype.com)
  • The crystalline lens , or lens, is a bi-convex structure in the eye that is transparent and which works with the cornea to refract light to focus on the retina. (advancedvisioncare.co.uk)
  • The natural lens of the eye, located behind the pupil, which helps bring rays of light to focus on the Retina, The original state of the lens is transparent, but the lens becomes cloudy with age (see Cataract). (consumersresearchcncl.org)
  • Refractive condition in which no refractive error is present and distant images are focused sharply on the Retina with no need for corrective lenses. (consumersresearchcncl.org)
  • Behind the iris is the lens, a transparent, elastic, but solid ellipsoid body that focuses the light on the retina, the third and innermost layer of tissue. (thefreedictionary.com)
  • The lens can then no longer transmit a clear picture to the retina where it can be processed and sent through the optic nerve to the brain. (nanowerk.com)
  • An intraocular lens having an anterior lens member (48) presenting an anterior light-converging optic (58) and a posterior lens member (50) presenting a posterior light-diverging optic (50) for magnifying an observed image onto large regions of the retina (32) to permit central focus in patients suffering. (google.com)
  • An intraocular lens having an anterior lens member ( 48 ) presenting an anterior light-converging optic ( 58 ) and a posterior lens member ( 50 ) presenting a posterior light-diverging optic ( 50 ) for magnifying an observed image onto large regions of the retina ( 32 ) to permit central focus in patients suffering from AMD and a method of implanting said lens into the human eye ( 10 ). (google.com)
  • My cataract had grown so dense after my vitrectomy about 2 years ago, that they could not see thru the lens to view my retina and could not see the PCO as well. (medhelp.org)
  • 25 Bietti crystalline dystrophy is a disorder in which numerous small, yellow or white crystal-like deposits of fatty (lipid) compounds accumulate in the light-sensitive tissue that lines the back of the eye (the retina). (malacards.org)
  • By changing shape, the lens bends, or refracts light onto the retina to create clear images of objects positioned at various distances. (everydaysight.com)
  • The lens changes shape to continue bending the rays and focuses the light onto the retina. (everydaysight.com)
  • As light passes through the cloudy lens it cannot focus clearly on the retina and creates a hazy or blurry picture. (everydaysight.com)
  • To image, describe, and characterize different features visible in the crystalline lens of older adults with and without cataract when imaged three-dimensionally with a swept-source optical coherence tomography (SS-OCT) system. (arvojournals.org)
  • Accommodation in the human eye occurs through controlled changes in crystalline lens shape, thickness, and refractive surface placement relative to the cornea. (google.com.au)
  • In alternative embodiments, an intraocular or intracorneal lens of the invention may be inserted in the anterior chamber, or within the cornea, of an eye of a patient. (google.co.uk)
  • Conventional extracapsular cataract extraction involves manual expression of the lens through an incision made in the cornea or sclera. (wikibooks.org)
  • Notice the lens is flatter anteriorally, facing the cornea (cornea). (utah.edu)
  • Despite some misconceptions due to the wide spectrum of terminology employed for describing eye anatomy, it is the cornea, not the lens, which is responsible for the major part of the total refractive power of the eye. (fsu.edu)
  • Although much thinner in width than the crystalline lens, the cornea provides about 65 percent of the eye's refractive power. (fsu.edu)
  • Intracorneal rings or corneal ring segments Implantable contact lenses Presbyopia reversal Anterior ciliary sclerotomy Scleral reinforcement surgery for the mitigation of degenerative myopia Corneal surgery includes most refractive surgery, as well as: Corneal transplant surgery is used to remove a cloudy/diseased cornea and replace it with a clear donor cornea. (wikipedia.org)
  • The initial step in our vision begins with light passing through the cornea where 65% to 75% is "pre-focused" before it even reaches the lens. (naturaleyecare.com)
  • A small incision is made in the cornea and a small opening is made into the capsule of the lens (capsulotomy) and an ultrasound probe emulsifies the lens which is then removed by suction. (cat-world.com.au)
  • The part of the eye anterior to the crystalline lens including the Cornea, Anterior Chamber, Iris and Ciliary Body. (consumersresearchcncl.org)
  • Between the cornea and iris and between the iris and lens are small spaces filled with aqueous humor, a thin, watery fluid. (thefreedictionary.com)
  • It is also present in the cornea and lens of the eye in crystalline form. (bodykind.com)
  • Surgical ways include corneal procedures (i.e., laser surgery on the cornea, thermokeratoplasty, and implantation of corneal inlays) and intraocular procedures that include cataract surgery or refractive lens exchange with the implantation of multifocal intraocular lenses or monofocal lenses with refractive target monovision. (hindawi.com)
  • The cornea bends, or refracts, the light and passes it through the pupil to the lens. (everydaysight.com)
  • Unlike the cornea that has a fixed shape, the lens changes shape to enable the eye to focus at various distances. (everydaysight.com)
  • Is not thin like the cornea, and this thickness contributes to the overall lens power. (dentisty.org)
  • The area behind the cornea, in front of the iris and the lens, filled with fluid called aqueous humour. (dentisty.org)
  • internal capsule the fanlike mass of white fibers separating the lentiform nucleus laterally from the head of the caudate nucleus, the dorsal thalamus, and the tail of the caudate nucleus medially. (thefreedictionary.com)
  • In an extracapsular surgery, the surgeon performs an anterior capsulotomy, or capsulorhexis, to create an opening through which the lens nucleus can be removed and the intraocular lens implant inserted. (wikibooks.org)
  • During lenticular development, the hyaloid artery delivers nutrition and growth factors through the tunica vasculosa lentis, a vascular structure that envelopes the lens nucleus. (utah.edu)
  • The OCT signal in the nucleus of the crystalline lens correlated with the nuclear cataract clinical grade. (arvojournals.org)
  • Nuclear cataracts are characterized by an increase of light scattering in the nucleus of the crystalline lens and can be accompanied by a myopic shift and an increase in yellow coloration due to the absorption of wavelengths in the blue end of the spectrum. (arvojournals.org)
  • Nuclear cataract where the opacity is in the center of the lens (nucleus). (healthhype.com)
  • Garland DL, Duglas-Tabor Y, Jimenez-Asensio J, Datiles MB, Magno B. The nucleus of the human lens: demonstration of a highly characteristic protein pattern by two-dimensional electrophoresis and introduction of a new method of lens dissection. (harvard.edu)
  • The making of a continuous circular tear in the anterior capsule during cataract surgery in order to allow expression or phacoemulsification of the nucleus of the lens. (bvsalud.org)
  • With the nucleus still in the bag at this stage, the surgeon is faced with the sizeable challenge of completing surgery without propagating a wrap-around tear to the posterior capsule. (bvsalud.org)
  • With cataracts, the normally clear lens becomes cloudy, affecting the transmission of light through the lens and resulting in loss of visual acuity. (google.com.au)
  • Cataracts are most frequently associated with the normal aging process or pathology, but injury or mechanical violation of the ocular capsule surrounding the lens also causes cataract formation. (google.com.au)
  • The partial or complete loss of transparency by the crystalline lens, or its capsule, results in a common condition known as cataracts . (fsu.edu)
  • Cataracts can affect part of or the entire lens and can be unilateral (one eye) or bilateral (both eyes). (cat-world.com.au)
  • The reason why the lens becomes opaque is complex and there are several mechanisms accounting for the different types of cataracts. (healthhype.com)
  • There are broadly three types of cataracts based on the location of the opacity in or on the lens. (healthhype.com)
  • The formation of cataracts in the elderly (senile cataracts) is probably due to a multitude of factors seen with aging - diminished regenerative properties, oxidative damage, hardening of the lens and any systemic illnesses. (healthhype.com)
  • There are a number of potential problems with the crystalline lens with, perhaps, cataracts being the best known. (advancedvisioncare.co.uk)
  • Cataracts themselves are opacities of the lens and some may be small and not need treatment while others will be big enough to block light and perfect vision. (advancedvisioncare.co.uk)
  • Cataracts usually develop as the lens becomes older and more opaque but they can be formed after an injury to the lens itself or congenitally. (advancedvisioncare.co.uk)
  • Cataracts can be operated on and the cataract surgery will see the removal of the lens and an artificial intraocular lens being inserted in its place. (advancedvisioncare.co.uk)
  • While cataract surgery is the most successful medical procedure, the inability to control penetration of the pharmacological agents into the lens and target specific intracellular biochemical pathways has impeded the success of pharmacological treatment of cataracts. (nanowerk.com)
  • Most cases of cataract are related to the aging process, as proteins in the lens degrade, but occasionally cataracts are congenital or develop after eye injuries, inflammation, or other eye diseases. (givewell.org)
  • Well-developed cataracts appear as gray, white, or yellow-brown opacities in the lens. (msdmanuals.com)
  • Lens Exchange vision correction surgery can help to get rid of all your spectacles for a lifetime, can prevent the formation of cataracts at a later age and ensure you enjoy the unique experience of clear vision without your glasses. (dentisty.org)
  • At this point, the lens vesicle is made up of a single layer of cells enveloped within an outer basement membrane. (utah.edu)
  • This basement membrane will eventually form the lens capsule. (utah.edu)
  • The elastic constants and ultrastructure of the basement membrane of the crystalline lens of the adult cat have been investigated. (royalsocietypublishing.org)
  • The basement membrane from the lens capsule of the eye is a collagen IV-rich matrix that can easily be extracted and manipulated in vitro. (elsevier.com)
  • Here we investigate the effects of increased transmembrane pressure and solute electrical charge on the transport properties of the lens basement membrane (LBM) from the bovine eye. (elsevier.com)
  • external capsule the layer of white fibers between the putamen and claustrum. (thefreedictionary.com)
  • As the secondary lens fibers elongate from the equator, they form Y-shaped sutures by meeting anteriorly and posteriorly during fetal growth. (utah.edu)
  • Lower section is of the posterior lens capsule, plc and cortical fibers (cf). (utah.edu)
  • The lens is held in place by zonular fibers, otherwise known as the zonules of Zinn (Fig. 4). (utah.edu)
  • These fibers are crystallins, water-soluble proteins that comprise 90% of the protein in the lens. (naturaleyecare.com)
  • It contains lens fibers and amorphous, intercellular substance. (harvard.edu)
  • Although the lens fibers have few organelles, their protein content is very high. (nanowerk.com)
  • In a preliminary study, the scientists demonstrate that passive diffusion of fluorescent nanoparticles (quantum dots) may be used to study the basic structure and biochemistry of cortical lens fibers. (nanowerk.com)
  • Fluorescent micrograph of a wet mount of human cortical lens fibers from a 34 year old donor, demonstrating the intracellular presence of (a) red fluorescent nanoparticles and (b) green fluorescent nanoparticles, 40x objective (Reprinted with permission from IOP Publishing). (nanowerk.com)
  • We were able to demonstrate that CdTe quantum dots diffused into the lens capsule and the cortical lens fibers but did not pass through the intact lens capsule' says Chen. (nanowerk.com)
  • This study shows that nanoparticles can be used as a method for studying intracellular structure and biochemical pathways within the lens capsule and cortical lens fibers to further understand cataractogenesis. (nanowerk.com)
  • In cataractous lens, hydration of the fibers occurs impairing transmission of light. (vetstream.com)
  • Lens fibers become swollen resulting in fiber membrane rupture, cytoplasmic extrusion and lens cell death. (vetstream.com)
  • As we age lens fibers grow denser and less elastic. (everydaysight.com)
  • 1 measured the change in anterior chamber depth and lens thickness of 13 young (18-21 years old) and 10 older (50-63 years old) subjects in the upright position, and in the prone position before and during maximum voluntary and pilocarpine-stimulated accommodation. (arvojournals.org)
  • Three-dimensional data were used to produce lens-capsule thickness maps. (bmj.com)
  • 2. The intraocular lens of claim 1 wherein the secondary deflection mechanism is a portion of the lens element having a reduced thickness. (google.com)
  • A-scan ultrasonography may reveal an increased lens thickness and B- scanultrasonography may show herniated lenticular material, suggestive of a lenticonus. (wikipedia.org)
  • Clinically, the capsule that was removed during the capsulorhexis appeared to be of normal thickness. (escrs.org)
  • True exfoliation of the lens capsule could masquerade as a partial capsulorrhexis and should be looked before capsulorrhexis to avoid creating a partial thickness capsulorrhexis and its related surgical complications. (escrs.org)
  • 14 . The lens of claim 9 , said flexible body having a thickness greater at the termini than the remainder of said body. (google.com)
  • 15 . The lens of claim 14 , said ratio in thickness of said body at a terminus to said remainder of said body being of from about 1:1 to 5:1. (google.com)
  • However, this new generation of formulas use the pre-operative ACD, without considering the thickness of the crystalline lens. (clinicaltrials.gov)
  • Therefore the thickness of the crystalline lens has a significant impact on the predicted post-operative position of the IOL. (clinicaltrials.gov)
  • Over time, some patients will develop an opacification of the posterior capsule behind the implant lens after the cataract has been removed. (bmj.com)
  • A cataract is a clouding/opacity of the lens in the eye due to proteins within the lens clumping together. (cat-world.com.au)
  • The lens also has specialized crystalline proteins that are capable of transmitting and refracting light. (healthhype.com)
  • Rao PV, Zigler JS, Garland D. Analysis of small GTP-binding proteins of the lens by GTP overlay assay reveals the presence of unique GTP-binding proteins associated with fiber cells. (harvard.edu)
  • In addition, there are three classes of proteins in the human lens. (nanowerk.com)
  • Even slight changes in lens protein shape, structure or to the overall protein arrangement and the interaction of the proteins with water can cause the scattering that reduces lens transparency, which results in a cataract. (nanowerk.com)
  • The arrangement of proteins that is needed to maintain transparency is still not fully understood, as to date it has not been possible to tag the proteins inside an intact lens. (nanowerk.com)
  • The crystalline lens is a transparent structure of the eye filled with proteins called crystallins. (everydaysight.com)
  • Subjects with anterior segment pathology in the eye to be treated that is not directly improved by lens extraction and IOL implantation. (clinicaltrials.gov)
  • A firm understanding of the embryology and development of the lens will provide great insight into the pathology associated with cataract formation. (utah.edu)
  • Statistical analysis revealed associations between steeper iris conicity and shallower anterior chamber depth, thicker human lens and higher corneal power in multivariable analysis, while older age was related to a flatter iris conicity. (hindawi.com)
  • Compared to the corneal procedures, the intraocular procedures suffer from one glaring handicap, that is, patients with the lens implants have to be under careful supervision of the ophthalmic surgeon throughout their lives to prevent or treat any adverse development. (medscape.com)
  • 71 Bietti crystalline corneoretinal dystrophy: An autosomal recessive ocular disease characterized by retinal degeneration and marginal corneal dystrophy. (malacards.org)
  • It has been attributed to several factors such as the pupil size, total and corneal aberrations, degrees and axis of astigmatism, potential of visual perception, and axial movement of the intraocular lens. (hindawi.com)
  • Finally the lens is pinched off and settles in place with the developing iris and ciliary body in the front of the eyeball (3). (utah.edu)
  • Cataract cannot usually be seen on casual inspection because it is happening in the lens which is just behind the iris and the pupil aperture. (everything2.com)
  • Associations indicate a correlation between iris conicity with risk factors for angle-closure, namely, shallower anterior chamber depth and thicker human lens. (hindawi.com)
  • The design of the iris claw lens has practically remained unchanged in the past 15 years. (medscape.com)
  • Phakic myopia iris claw lens, 11 years postoperatively. (medscape.com)
  • It reduces the chances of pressure by the lens haptics and the optic on the natural lens and the iris, in case a bigger knuckle of iris is drawn inside the claw. (medscape.com)
  • Anterior segment fluorescein angiography in a case of iris claw lens (Artisan lens) in a phakic myope. (medscape.com)
  • The Visian implantable collamer lens (ICL), marketed by Staar Surgical, is a posterior-chamber phakic IOL, meaning it is positioned behind the iris and in front of the crystalline lens. (medscape.com)
  • The Visian ICL is intended to be implanted within the posterior chamber, directly behind the iris, and in front of the anterior capsule of the human crystalline lens. (clinicaltrials.gov)
  • The amount of light that strikes the lens is regulated by the outer iris which contracts the central pupil size in bright light and expands it in dim light. (naturaleyecare.com)
  • The lens is transparent crystalline structure encased in a capsule which sits behind the pupil and iris, the coloured part of the eye. (cat-world.com.au)
  • The amount of light entering the eye is controlled by the iris, which sits in front of the lens. (advancedvisioncare.co.uk)
  • The medical approach includes mydriatic and cycloplegic agents to relax the ciliary muscle and tighten the lens zonules, giving a posterior push to the iris and crystalline lens diaphragms. (eyeworld.org)
  • The lenses of New Zealand White and Flemish Giant rabbits were removed using five techniques representative of the different clinical approaches to extracapsular cataract extraction currently employed. (nih.gov)
  • Extracapsular cataract extraction involves the removal of the lens while the elastic lens capsule is left partially intact to allow implantation of an intraocular lens [2] . (wikibooks.org)
  • Intracapsular cataract extraction (ICCE) involves the removal of the lens and the surrounding lens capsule in one piece. (wikibooks.org)
  • Although it is now used primarily for the removal of subluxated lenses, it was the favored form of cataract extraction from the late 1960s to the early 1980s [5] . (wikibooks.org)
  • An opacification or clouding of the posterior lens capsule frequently occurs in those who have had an extracapsular cataract extraction procedure, therefore, a laser posterior capsulotomy, or YAG laser capsulotomy, is used to clear the back implant surface [6] . (wikibooks.org)
  • For the stabilization of the crystalline lens capsule in the presence of weak or partially absent zonules in adult patients undergoing cataract extraction with intraocular lens implantation. (bausch.com)
  • The development of posterior capsule opacification secondary to extracapsular cataract extraction is a common occurrence. (nih.gov)
  • The majority of catacacts are caused by aging , which triggers chemical changes in the eye's natural lens. (everything2.com)
  • The present invention pertains to accommodating intraocular lens (AIOL) assemblies (31) including a haptics system (32) for self-anchoring implantation in a human eye's annular ciliary sulcus (28) for retaining an AIOL (33) at a desired position along the human eye's visual axis (36), and an accommodation. (google.com.au)
  • The present invention pertains to accommodating intraocular lens (AIOL) assemblies (31) including a haptics system (32) for self-anchoring implantation in a human eye's annular ciliary sulcus (28) for retaining an AIOL (33) at a desired position along the human eye's visual axis (36), and an accommodation measurement implant (AMI) for determining accommodation and accommodation forces in an experimental set-up including an animal's eye. (google.com.au)
  • Cataract surgery involves removal of the eye's natural lens, followed by implantation of an artificial intraocular lens. (givewell.org)
  • Bietti Crystalline Corneoretinal Dystrophy, also known as bietti crystalline dystrophy , is related to blepharocheilodontic syndrome 1 and choroiditis , and has symptoms including progressive visual loss , abnormality of blood and blood-forming tissues and progressive night blindness . (malacards.org)
  • Bietti Crystalline Corneoretinal Dystrophy, also known as bietti crystalline dystrophy , is related to retinitis pigmentosa and blepharocheilodontic syndrome 1 . (malacards.org)
  • Phacoemulsification - Surgery to remove the lens and replace it with an artificial one. (cat-world.com.au)
  • Extracapsular lens extraction - Surgical removal of the entire lens if it is too solid to be break up, or the practice doesn't have the necessary equipment for phacoemulsification. (cat-world.com.au)
  • After the lens is stabilized by the AssiAnchor, the surgeon performs phacoemulsification in the conventional manner. (crstoday.com)
  • A primary tear-out of the capsulorrhexis or a later anterior capsule tear occurs in less than 1% of phacoemulsification procedures [Marques et al. (bvsalud.org)
  • All eyes underwent phacoemulsification with implantation of intraocular lenses. (bvsalud.org)
  • This retrospective study comprised 14 eyes of eight patients who had RLE to treat myopia of −19.0±5.4 diopters (D). Phacoemulsification, posterior chamber intraocular lens (IOL) implantation, and standard three-port vitrectomy were performed. (nature.com)
  • The thin noncellular outer covering of the CRYSTALLINE LENS composed mainly of collagen type iv and glycosaminoglycans . (lookfordiagnosis.com)
  • The lens is contained within a flexible capsule or sac composed of collagen. (naturaleyecare.com)
  • A conduit through which a drug is introduced penetrates at least the outer lens capsule for drug delivery. (google.com.au)
  • 1 . An ocular drug delivery method comprising penetrating at least an outer capsule of an ocular lens with a conduit to create an aperture in the lens and introducing a drug into the lens through the aperture, wherein the aperture is self-sealing upon removal of the conduit. (google.com.au)
  • 14 . A localized ocular drug delivery method comprising penetrating at least an outer capsule of an ocular lens with a conduit to create an aperture, providing an agent directly into the lens via the conduit through the aperture, and withdrawing the conduit wherein the agent is substantially confined within the lens. (google.com.au)
  • One embodiment of the invention is an ocular drug delivery method by penetrating at least the outer capsule of the lens with a fine conduit that creates a self-sealing aperture when it is removed, then introducing a drug into the lens through this aperture. (google.com.au)
  • 9 . The intraocular lens of claim 8 , wherein said at least one arcuate corrugation further comprises a first outer arcuate corrugation and a second outer arcuate corrugation, said first outer arcuate corrugation and said second outer arcuate corrugation disposed adjacent to, and radially outward from, said inner partial annulus. (google.co.uk)
  • 10 . The intraocular lens of claim 9 , wherein said first outer arcuate corrugation and said second outer arcuate corrugation jointly form an outer partial annulus. (google.co.uk)
  • 11 . The intraocular lens of claim 10 , wherein each of said inner partial annulus and said outer partial annulus is concentric with said optical portion. (google.co.uk)
  • During cataract surgery the outer shell (capsule) of the natural lens is left behind to hold the artificial lens (implant). (drugster.info)
  • The crystalline lens has a cellophane-like outer lining called the capsule. (asiaretina.com)
  • They concluded that the reduction in anterior chamber depth in the prone position during high levels of accommodation slackens the zonules sufficiently to allow the lens to move under the effect of gravity. (arvojournals.org)
  • The lens is suspended in place from tiny ciliary muscles by hundreds of fine ligaments called zonules. (naturaleyecare.com)
  • If the zonules appeared pathologic and the lens seemed to be unstable as the case began, I would place retractors from the Mackool Cataract Support System (Duckworth & Kent Ltd., Hertfordshire, United Kingdom) as I performed the capsulorhexis. (crstoday.com)
  • 1 Another theory attributes the forward lens movement seen in this condition to laxity of the lens zonules. (eyeworld.org)
  • The delicate, yet strong zonules connect to the ciliary body to suspend the lens in position. (everydaysight.com)
  • In the relaxed state the ciliary muscles pull on the zonules increasing their tension on the lens. (everydaysight.com)
  • The zonules pull on the lens around its equator causing the entire lens to become flatter, or less convex. (everydaysight.com)
  • When the zonules loosen, the lens thickens, or becomes rounder in shape. (everydaysight.com)
  • A blunt injury to the eye can disrupt the zonules dislocating the lens in any direction. (everydaysight.com)
  • Cataract is the leading cause of blindness worldwide, 1 and is a condition characterized by the progressive loss of the transparency of the crystalline lens that results in visual impairment. (arvojournals.org)
  • Cataract is the loss of transparency of the crystalline lens in the eye. (everything2.com)
  • An opacity or loss of transparency of the crystalline lens which results in loss of light transmission, image degradation and reduced vision. (consumersresearchcncl.org)
  • Lens transparency is thought to depend on short-range order of these protein classes within the lens. (nanowerk.com)
  • In conclusion, P. densiflora bark extract prevented selenite-induced cataract formation via regulating antioxidant enzymes, inhibiting m -calpain-induced proteolysis, and apoptosis, and thus, maintained the transparency of the lens. (molvis.org)
  • Soemmering's ring, which is a type of PCO also called a regenerated lens with similar tissue structure to that of a human lens, is an important proxy for elucidating the mechanism of lens regeneration and maintenance of transparency. (fujita-hu.ac.jp)
  • By further improving the culture conditions, we aim to control the cell sequence and elucidate the mechanism underlying the maintenance of lens transparency. (fujita-hu.ac.jp)
  • Histological section of normal crystalline lens (H&E stain, X2). (utah.edu)
  • It has also been referred to as aqueous misdirection, ciliary block glaucoma, and lens block angle closure. (eyeworld.org)
  • The lens relies on the aqueous humor for nutrition and waste removal. (everydaysight.com)
  • To evaluate rates of intraoperative posterior capsule complications in manual small-incision cataract surgery of eyes with and without pseudoexfoliation syndrome in terms of cataract maturity level. (nih.gov)
  • Intraoperative posterior capsule complications occurred in 18 eyes (18%) in group 1 and 7 eyes (5.5%) in group 2 (difference was significant at p=0.003). (nih.gov)
  • In manual small-incision cataract surgery, pseudoexfoliation syndrome has an increased intraoperative posterior capsule complication rate that increases as the level of cataract maturity increases and the preoperative visual acuity decreases. (nih.gov)
  • It offers an intraocular alternative for the correction of refractive error in those who currently utilize spectacle and/or contact lenses correction. (clinicaltrials.gov)
  • It produces a decrease in visual acuity and irregular refraction that cannot be corrected by either spectacle or contact lenses. (wikipedia.org)
  • Nonsurgical ways are with properly designed spectacles and contact lenses. (hindawi.com)
  • Eyeglasses or contact lenses are usually required for best vision after cataract surgery. (dentisty.org)
  • The natural lens is then replaced with an artificial intraocular lens. (wikibooks.org)
  • Today, an Intraocular Lens (IOL) is implanted in the eye after the Cataract is removed to replace the focusing power of the natural lens eliminating the need for Aphakic Spectacles. (consumersresearchcncl.org)
  • To describe the results of refractive lens exchange (RLE) combined with simultaneous pars plana vitrectomy (PPV) in the management of severe myopia. (nature.com)
  • At present, there are principally three techniques including laser in situ keratomileusis (LASIK), phakic intraocular lens (IOL) implantation, and refractive lens exchange (RLE). (nature.com)
  • The lens is then replaced with an artificial plastic lens (an intraocular lens implant) of appropriate power which remains permanently in the eye. (wikibooks.org)
  • During cataract surgery the lens is removed from this sac and replaced by an artificial lens). (naturaleyecare.com)
  • The veterinarian inserts the artificial intraocular lens. (cat-world.com.au)
  • Even if we implant the artificial lens into the capsule in PEX eye, there is some possibility of dislocation of the capsule with intraocular lens in the future. (ocniatlas.cz)
  • The treatment of cataract involves surgical removal of the old lens and implantation of a new artificial intraocular lens. (molvis.org)
  • In most cases the cataract is replaced by an artificial lens made of polymethyl methacrylate, acrylic, or silicone. (bmj.com)
  • Cataract cannot recur in an eye with an artificial lens. (givewell.org)
  • In the attempt to manage presbyopia, different intraocular lens designs have been proposed such as monofocal IOLs with monovision or multifocal IOLs. (hindawi.com)
  • Newer premium lenses that are designed to correct either astigmatism or presbyopia and, in the process, make people less dependent on glasses, are now an option for some patients. (uclahealth.org)
  • This process of the aging lens is called presbyopia. (everydaysight.com)
  • After the surgery, an intraocular lens implant ( IOL )is suture d ( stitched with a microscopically fine thread) over the the eye , and the benign shell of the caract is left to speed recovery. (everything2.com)
  • If the zonule (the structure on which the crystalline lens "hangs") is very weak, it can be destroyed during the surgery and we can´t implant the new intraocular lens in it´s best place - into the capsule, but we have to find another way to fix it in the eye. (ocniatlas.cz)
  • If an implant lens is not used, or there is remaining refractive error (e.g., astigmatism that is uncorrected by the implant lens), the patient may need to wear either a contact lens or spectacles to achieve good postoperative vision. (bmj.com)
  • In most cataract surgeries, the posterior capsule has been left intact to support the intraocular lens implant that was inserted at the time of surgery. (asiaretina.com)
  • Image above showing an intraocular implant placed in the original lens capsule. (asiaretina.com)
  • A capsulotomy, rarely known as cystitomy, is a procedure to open a portion of the lens capsule. (wikibooks.org)
  • An anterior capsulotomy refers to the opening of the front portion of the lens capsule, whereas a posterior capsulotomy refers to the opening of the back portion of the lens capsule. (wikibooks.org)
  • Whereas a capsulotomy is the creation of an opening in the lens capsule, a capsulectomy is the acutal removal of lens capsule tissue. (wikibooks.org)
  • The YAG laser posterior capsulotomy has become standard treatment for this anomaly: an opening is created in the opacified posterior capsule, which immediately improves visual acuity. (nih.gov)
  • During the 30 months follow-up period three eyes (21.4%) required neodymium : yttrium-aluminium-garnet (Nd : YAG) capsulotomy for posterior capsule opacification. (nature.com)
  • A laser treatment known as YAG laser capsulotomy can be done to improve your vision by creating an opening in the cloudy lens capsule to allow the clear passage of light. (asiaretina.com)
  • Nine subjects [mean age: 30 years, range: 25-38 years] were studied, each of whom had undergone a phakic refractive intraocular lens (PRL) surgical procedure. (bmj.com)
  • If visual loss is significant, surgical removal of the lens may be warranted, with lost optical power usually replaced with a plastic intraocular lens (IOL). (wikibooks.org)
  • The treatment involves surgical cataract removal followed by placement of an intraocular lens (IOL). (everything2.com)
  • It is an extremely successful surgical procedure in which the crystalline lens, which has become cloudy or opaque, is extracted. (everything2.com)
  • Owing to its flexibility, the lens can be folded during implantation, requiring only a small surgical incision. (medscape.com)
  • Both the anterior and the posterior lens members ( 48, 50 ) have positioning holes ( 70, 80 ) formed therein permitting surgical implantation thereof. (google.com)
  • Aphakia is the absence of the lens, due to surgical removal, or a congenital anomaly. (everydaysight.com)
  • Treatment is surgical removal and placement of an intraocular lens. (msdmanuals.com)
  • The ciliary muscles adjust the lens to enable us to see near, middle and far distances clearly by relaxing to see distant objects and contracting to see objects near at hand. (naturaleyecare.com)
  • An accommodating intraocular lens is provided having optical parameters that are altered in-situ, wherein an optic portion of the lens includes an actuator that deflects a lens element to alter the optical power of the lens, responsive to forces applied to a haptic portion to the lens by contraction of the ciliary muscles. (google.co.uk)
  • The optic portion of the lens includes an actuator that deflects a lens element to alter the optical power of the lens responsive to forces applied to the haptic portion of the lens by contraction of the ciliary muscles and. (google.com)
  • For the lens to work, the ciliary muscles change the shape of the lens which enables the eye to focus on objects at different distances. (advancedvisioncare.co.uk)
  • The ciliary muscles control the convexity (outward curvature) of the lens in response to the distance of the object being viewed. (everydaysight.com)
  • Imagine the ciliary muscles surrounding the lens as a tiny doughnut. (everydaysight.com)
  • The lens becomes stiff making it more difficult for the ciliary muscles to change the shape of the lens causing impaired vision. (everydaysight.com)
  • ABSTRACT This study aimed to analyze the anterior lens capsule specimens from both eyes of a patient with systemic sclerosis and compare them to the eyes of a control patient. (bvsalud.org)
  • abstract = "The incidence rate of post-cataract surgery posterior capsule opacification (PCO) and lens turbidity is about 20% in 5 years. (fujita-hu.ac.jp)
  • This study will evaluate the clinical performance of a phakic intraocular lens (IOL) for the improvement of Uncorrected Near Visual Acuity (UCNVA) in subjects who require between +1.00 and +2.50 Reading Add. (clinicaltrials.gov)
  • Diagnosis is made by the detection of a decrease in visual acuity that cannot be corrected by refractive correction, and an eye exam that is otherwise normal apart from opacity in the crystalline lens. (bmj.com)
  • A dedicated OCT is a useful tool to study in vivo the subtle opacities in the cataractous crystalline lens, revealing its position and size three-dimensionally. (arvojournals.org)
  • Morris MS, Jacques PF, Hankinson SE, Chylack LT, Willett WC, Taylor A. Moderate alcoholic beverage intake and early nuclear and cortical lens opacities. (harvard.edu)
  • Opacities are caused by metabolic and/or anatomical disturbances to normal lens structure and function. (vetstream.com)
  • 9. The method recited in Claim 8 wherein the lens is a cataractous lens. (google.se)
  • cataract and lens opacity are the earliest complications experienced by DM patients, which are characterized by severe metabolic disorders and high blood glucose level [ 5 , 6 ]. (portlandpress.com)
  • Nuclear sclerosis occurs as the lens loses water due to aging, does not impede vision and requires no treatment. (cat-world.com.au)
  • Reactive oxygen species (ROS) production, lipid peroxidation, reduction of antioxidant enzymes, crystalline proteolysis, and apoptosis are considered factors that contribute to pathogenesis of age-related nuclear cataract. (molvis.org)
  • Pseudoexfoliations on the anterior surface of the crystalline lens. (ocniatlas.cz)
  • The immature lenticular cells thicken to form the lens placode. (utah.edu)
  • 13 . A method that minimizes cataract formation when an agent is provided to an ocular lens, the method comprising piercing the lens with a needle of 30 gauge or thinner, introducing an agent into the lens through the needle, and withdrawing the needle from the lens. (google.com.au)
  • A cataract refers to any opacity of the ocular crystalline lens. (google.com.au)
  • Great antioxidant eye drop for ocular and eye lens health. (naturaleyecare.com)
  • Cataract is an opacity in the lens, primary cataract occurs in the absence of any other ocular disease has a bilateral potential and is hereditary. (vetstream.com)
  • In this paper, we consider the ocular lens in the context of contemporary developments in biological ideas. (biomedcentral.com)
  • A congenital cataract is opacification of the lens that occurs in the fetus at some time during pregnancy. (everything2.com)
  • This occurs as a result of sclerosis (abnormal hardening) of the lens with accumulation of urochrome pigment causing the lens to become yellow or brown. (healthhype.com)
  • Figure 3 shows a stained section of the adult human lens with anterior part of the lens in the top section and the posterior part in the lower section. (utah.edu)
  • My clinical experience (11 patients, 12 anchors) has been encouraging, and final follow-up (more than 2 years for four patients) revealed stable and central capsule-fixated IOLs in all eyes. (crstoday.com)
  • Surgery involves removing the cloudy lens and replacing it with a plastic intraocular lens (IOL). (uclahealth.org)
  • Months or years after cataract surgery, the posterior capsule (behind the intraocular lens) may become cloudy. (uclahealth.org)
  • This thickening of the capsule causes your vision to become cloudy. (dentisty.org)
  • Posterior capsular opacification (PCO) results from the proliferation and migration of cells within the lens capsule, causing it to become wrinkled or cloudy. (asiaretina.com)
  • Image above shows how the YAG laser makes an opening in the cloudy posterior capsule. (asiaretina.com)
  • The intraocular lens may be deformed before or during insertion in an eye of a patient, and may be positioned in the posterior chamber of the eye such that the optical portion is spaced anteriorly from the crystalline lens of the eye. (google.co.uk)