Lectins. Medical search

Proteins that share the common characteristic of binding to carbohydrates. Some ANTIBODIES and carbohydrate-metabolizing proteins (ENZYMES) also bind to carbohydrates, however they are not considered lectins. PLANT LECTINS are carbohydrate-binding proteins that have been primarily identified by their hemagglutinating activity (HEMAGGLUTININS). However, a variety of lectins occur in animal species where they serve diverse array of functions through specific carbohydrate recognition.

Protein or glycoprotein substances of plant origin that bind to sugar moieties in cell walls or membranes. Some carbohydrate-metabolizing proteins (ENZYMES) from PLANTS also bind to carbohydrates, however they are not considered lectins. Many plant lectins change the physiology of the membrane of BLOOD CELLS to cause agglutination, mitosis, or other biochemical changes. They may play a role in plant defense mechanisms.

A subclass of lectins that are specific for CARBOHYDRATES that contain MANNOSE.

Lectins purified from the germinating seeds of common wheat (Triticum vulgare); these bind to certain carbohydrate moieties on cell surface glycoproteins and are used to identify certain cell populations and inhibit or promote some immunological or physiological activities. There are at least two isoforms of this lectin.

A class of animal lectins that bind to carbohydrate in a calcium-dependent manner. They share a common carbohydrate-binding domain that is structurally distinct from other classes of lectins.

A class of animal lectins that bind specifically to beta-galactoside in a calcium-independent manner. Members of this class are distiguished from other lectins by the presence of a conserved carbohydrate recognition domain. The majority of proteins in this class bind to sugar molecules in a sulfhydryl-dependent manner and are often referred to as S-type lectins, however this property is not required for membership in this class.

Carbohydrates covalently linked to a nonsugar moiety (lipids or proteins). The major glycoconjugates are glycoproteins, glycopeptides, peptidoglycans, glycolipids, and lipopolysaccharides. (From Biochemical Nomenclature and Related Documents, 2d ed; From Principles of Biochemistry, 2d ed)

Lectin purified from peanuts (ARACHIS HYPOGAEA). It binds to poorly differentiated cells and terminally differentiated cells and is used in cell separation techniques.

The largest class of organic compounds, including STARCH; GLYCOGEN; CELLULOSE; POLYSACCHARIDES; and simple MONOSACCHARIDES. Carbohydrates are composed of carbon, hydrogen, and oxygen in a ratio of Cn(H2O)n.

A MANNOSE/GLUCOSE binding lectin isolated from the jack bean (Canavalia ensiformis). It is a potent mitogen used to stimulate cell proliferation in lymphocytes, primarily T-lymphocyte, cultures.

Glycosides formed by the reaction of the hydroxyl group on the anomeric carbon atom of galactose with an alcohol to form an acetal. They include both alpha- and beta-galactosides.

A plant genus in the family LILIACEAE (sometimes classified as Amaryllidaceae). Galanthus nivalis L. is the source of GALANTHAMINE.

The N-acetyl derivative of galactosamine.

A family of calcium-binding alpha-globulins that are synthesized in the LIVER and play an essential role in maintaining the solubility of CALCIUM in the BLOOD. In addition the fetuins contain aminoterminal cystatin domains and are classified as type 3 cystatins.

Glycoprotein molecules on the surface of B- and T-lymphocytes, that react with molecules of antilymphocyte sera, lectins, and other agents which induce blast transformation of lymphocytes.

The aggregation of ERYTHROCYTES by AGGLUTININS, including antibodies, lectins, and viral proteins (HEMAGGLUTINATION, VIRAL).

Cellular processes in biosynthesis (anabolism) and degradation (catabolism) of CARBOHYDRATES.

The clumping together of suspended material resulting from the action of AGGLUTININS.

A hexose or fermentable monosaccharide and isomer of glucose from manna, the ash Fraxinus ornus and related plants. (From Grant & Hackh's Chemical Dictionary, 5th ed & Random House Unabridged Dictionary, 2d ed)

The sequence of carbohydrates within POLYSACCHARIDES; GLYCOPROTEINS; and GLYCOLIPIDS.

A plant genus of the family FABACEAE. Canavalia ensiformis is the source of CONCANAVALIN A.

A plant genus of the family MORACEAE. Puag-haad extract, from A. lakoocha, contains STILBENES and related 4-substituted RESORCINOLS.

A plant genus of the family EUPHORBIACEAE, order Euphorbiales, subclass Rosidae. The seed of Ricinus communis L. is the CASTOR BEAN which is the source of CASTOR OIL; RICIN; and other lectins.

An aldohexose that occurs naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins. Deficiency of galactosyl-1-phosphate uridyltransferase (GALACTOSE-1-PHOSPHATE URIDYL-TRANSFERASE DEFICIENCY DISEASE) causes an error in galactose metabolism called GALACTOSEMIA, resulting in elevations of galactose in the blood.

Ribosome inactivating proteins consisting of two polypeptide chains, the toxic A subunit and a lectin B subunit, linked by disulfide bridges. The lectin portion binds to cell surfaces and facilitates transport into the ENDOPLASMIC RETICULUM.

Agents that cause agglutination of red blood cells. They include antibodies, blood group antigens, lectins, autoimmune factors, bacterial, viral, or parasitic blood agglutinins, etc.

Substances, usually of biological origin, that cause cells or other organic particles to aggregate and stick to each other. They include those ANTIBODIES which cause aggregation or agglutination of particulate or insoluble ANTIGENS.

Sensitive tests to measure certain antigens, antibodies, or viruses, using their ability to agglutinate certain erythrocytes. (From Stedman, 26th ed)

Endogenous glycoproteins from which SIALIC ACID has been removed by the action of sialidases. They bind tightly to the ASIALOGLYCOPROTEIN RECEPTOR which is located on hepatocyte plasma membranes. After internalization by adsorptive ENDOCYTOSIS they are delivered to LYSOSOMES for degradation. Therefore receptor-mediated clearance of asialoglycoproteins is an important aspect of the turnover of plasma glycoproteins. They are elevated in serum of patients with HEPATIC CIRRHOSIS or HEPATITIS.

Glycosides formed by the reaction of the hydroxyl group on the anomeric carbon atom of mannose with an alcohol to form an acetal. They include both alpha- and beta-mannosides.

Conjugated protein-carbohydrate compounds including mucins, mucoid, and amyloid glycoproteins.

Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.

The N-acetyl derivative of glucosamine.

Parasitic plants that form a bushy growth on branches of host trees which are in the order Santalales. It includes the Christmas mistletoe family (VISCACEAE), the showy mistletoe family (LORANTHACEAE) and the catkin mistletoe family (Eremolepidaceae). The composition of toxins, lectins, tyramine, phenethylamines, and other compounds may be affected by the host.

A chromatographic technique that utilizes the ability of biological molecules to bind to certain ligands specifically and reversibly. It is used in protein biochemistry. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

N-Glycosidases that remove adenines from RIBOSOMAL RNA, depurinating the conserved alpha-sarcin loop of 28S RIBOSOMAL RNA. They often consist of a toxic A subunit and a binding lectin B subunit. They may be considered as PROTEIN SYNTHESIS INHIBITORS. They are found in many PLANTS and have cytotoxic and antiviral activity.

Plants whose roots, leaves, seeds, bark, or other constituent parts possess therapeutic, tonic, purgative, curative or other pharmacologic attributes, when administered to man or animals.

Carbohydrates consisting of between two (DISACCHARIDES) and ten MONOSACCHARIDES connected by either an alpha- or beta-glycosidic link. They are found throughout nature in both the free and bound form.

The large family of plants characterized by pods. Some are edible and some cause LATHYRISM or FAVISM and other forms of poisoning. Other species yield useful materials like gums from ACACIA and various LECTINS like PHYTOHEMAGGLUTININS from PHASEOLUS. Many of them harbor NITROGEN FIXATION bacteria on their roots. Many but not all species of "beans" belong to this family.

An N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518)

Cell surface receptors that bind to ACETYLGLUCOSAMINE.

The chemical or biochemical addition of carbohydrate or glycosyl groups to other chemicals, especially peptides or proteins. Glycosyl transferases are used in this biochemical reaction.

Mannosides formed by the reaction of the hydroxyl group on the anomeric carbon atom of mannose with methyl alcohol. They include both alpha- and beta-methylmannosides.

A toxic lectin from the seeds of jequirity, Abrus precatorius L. Very active poison. Five different proteins have so far been isolated: Abrus agglutinin, the component responsible for: hemagglutinating activity, & abrins a-d, the toxic principals each consisting of two peptide chains are held together by disulfide bonds.

Mucoproteins isolated from the kidney bean (Phaseolus vulgaris); some of them are mitogenic to lymphocytes, others agglutinate all or certain types of erythrocytes or lymphocytes. They are used mainly in the study of immune mechanisms and in cell culture.

The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.

Simple sugars, carbohydrates which cannot be decomposed by hydrolysis. They are colorless crystalline substances with a sweet taste and have the same general formula CnH2nOn. (From Dorland, 28th ed)

A genus of leguminous shrubs or trees, mainly tropical, yielding useful compounds such as ALKALOIDS and PLANT LECTINS.

A galectin found abundantly in smooth muscle (MUSCLE, SMOOTH) and SKELETAL MUSCLE and many other tissues. It occurs as a homodimer with two 14-kDa subunits.

Study of intracellular distribution of chemicals, reaction sites, enzymes, etc., by means of staining reactions, radioactive isotope uptake, selective metal distribution in electron microscopy, or other methods.

A plant genus in the family CAPRIFOLIACEAE known for elderberries.

The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.

A group of naturally occurring N-and O-acyl derivatives of the deoxyamino sugar neuraminic acid. They are ubiquitously distributed in many tissues.

The parts of a macromolecule that directly participate in its specific combination with another molecule.

Glycoprotein moieties on the surfaces of cell membranes that bind concanavalin A selectively; the number and location of the sites depends on the type and condition of the cell.

A multifunctional galactin initially discovered as a macrophage antigen that binds to IMMUNOGLOBULIN E, and as 29-35-kDa lectin that binds LAMININ. It is involved in a variety of biological events including interactions with galactose-containing glycoconjugates, cell proliferation, CELL DIFFERENTIATION, and APOPTOSIS.

Electrophoresis in which a polyacrylamide gel is used as the diffusion medium.

The characteristic 3-dimensional shape of a carbohydrate.

Tests that are dependent on the clumping of cells, microorganisms, or particles when mixed with specific antiserum. (From Stedman, 26th ed)

Any compound that contains a constituent sugar, in which the hydroxyl group attached to the first carbon is substituted by an alcoholic, phenolic, or other group. They are named specifically for the sugar contained, such as glucoside (glucose), pentoside (pentose), fructoside (fructose), etc. Upon hydrolysis, a sugar and nonsugar component (aglycone) are formed. (From Dorland, 28th ed; From Miall's Dictionary of Chemistry, 5th ed)

A class of C-type lectins that target the carbohydrate structures found on invading pathogens. Binding of collectins to microorganisms results in their agglutination and enhanced clearance. Collectins form trimers that may assemble into larger oligomers. Each collectin polypeptide chain consists of four regions: a relatively short N-terminal region, a collagen-like region, an alpha-helical coiled-coil region, and carbohydrate-binding region.

A galectin found in the small and large intestine and the stomach. It occurs as a homodimer with two 36-kDa subunits and is localized to sites of cell adhesion where it may play role in assembly of ADHERENS JUNCTIONS.

Common name for Ricinus communis, a species in the family EUPHORBIACEAE. It is the source of CASTOR OIL.

A plant genus in the family ARALIACEAE, order Apiales, subclass Rosidae. It includes Aralia californica S. Watson, Aralia nudicaulis L., and Aralia racemosa L.

A class of Echinodermata characterized by long, slender bodies.

An enzyme that catalyzes the hydrolysis of alpha-2,3, alpha-2,6-, and alpha-2,8-glycosidic linkages (at a decreasing rate, respectively) of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid, and synthetic substrate. (From Enzyme Nomenclature, 1992)

A disaccharide of GLUCOSE and GALACTOSE in human and cow milk. It is used in pharmacy for tablets, in medicine as a nutrient, and in industry.

A plant species of the genus DATURA, family SOLANACEAE, that contains TROPANES and other SOLANACEOUS ALKALOIDS.

A protein phytotoxin from the seeds of Ricinus communis, the castor oil plant. It agglutinates cells, is proteolytic, and causes lethal inflammation and hemorrhage if taken internally.

A monocot family within the order Liliales. This family is divided by some botanists into other families such as Convallariaceae, Hyacinthaceae and Amaryllidaceae. Amaryllidaceae, which have inferior ovaries, includes CRINUM; GALANTHUS; LYCORIS; and NARCISSUS and are known for AMARYLLIDACEAE ALKALOIDS.

A plant genus of the family Musaceae, order Zingiberales, subclass Zingiberidae, class Liliopsida.

The encapsulated embryos of flowering plants. They are used as is or for animal feed because of the high content of concentrated nutrients like starches, proteins, and fats. Rapeseed, cottonseed, and sunflower seed are also produced for the oils (fats) they yield.

Proteins which are present in or isolated from SOYBEANS.

Proteins which contain carbohydrate groups attached covalently to the polypeptide chain. The protein moiety is the predominant group with the carbohydrate making up only a small percentage of the total weight.

A plant species of the family FABACEAE that yields edible seeds, the familiar peanuts, which contain protein, oil and lectins.

The major human blood type system which depends on the presence or absence of two antigens A and B. Type O occurs when neither A nor B is present and AB when both are present. A and B are genetic factors that determine the presence of enzymes for the synthesis of certain glycoproteins mainly in the red cell membrane.

The sum of the weight of all the atoms in a molecule.

A plant genus of the family FABACEAE. Members contain isoacteoside, luteolin, indole-3-carboxylic acid.

An arthropod subclass (Xiphosura) comprising the North American (Limulus) and Asiatic (Tachypleus) genera of horseshoe crabs.

Multicellular, eukaryotic life forms of kingdom Plantae (sensu lato), comprising the VIRIDIPLANTAE; RHODOPHYTA; and GLAUCOPHYTA; all of which acquired chloroplasts by direct endosymbiosis of CYANOBACTERIA. They are characterized by a mainly photosynthetic mode of nutrition; essentially unlimited growth at localized regions of cell divisions (MERISTEMS); cellulose within cells providing rigidity; the absence of organs of locomotion; absence of nervous and sensory systems; and an alternation of haploid and diploid generations.

Specific, characterizable, poisonous chemicals, often PROTEINS, with specific biological properties, including immunogenicity, produced by microbes, higher plants (PLANTS, TOXIC), or ANIMALS.

The first alpha-globulins to appear in mammalian sera during FETAL DEVELOPMENT and the dominant serum proteins in early embryonic life.

A specific mannose-binding member of the collectin family of lectins. It binds to carbohydrate groups on invading pathogens and plays a key role in the MANNOSE-BINDING LECTIN COMPLEMENT PATHWAY.

The systematic study of the structure and function of the complete set of glycans (the glycome) produced in a single organism and identification of all the genes that encode glycoproteins.

The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.

SUGARS containing an amino group. GLYCOSYLATION of other compounds with these amino sugars results in AMINOGLYCOSIDES.

Lymphocyte proliferation inhibitory factor (PIF) in alcoholic liver disease. (1/6088)

Lymphocyte proliferation inhibitory factor (PIF) was determined in the supernatants of PHA-stimulated lymphocytes from patients with alcoholic liver disease. PIF was assayed by determining inhibition of DNA synthesis in WI-38 human lung fibroblasts. A two-fold greater inhibition in thymidine incorporation into DNA by lung fibroblasts was observed in supernatants of PHA stimulated lymphocytes from patients with alcoholic hepatitis or active Laennec's cirrhosis as compared with that found in control subjects or patients with fatty liver. It is suggested that decreased liver cell regeneration seen in some patients with alcoholic hepatitis may be due to increased elaboration of PIF. (+info)

Structure of CD94 reveals a novel C-type lectin fold: implications for the NK cell-associated CD94/NKG2 receptors. (2/6088)

The crystal structure of the extracellular domain of CD94, a component of the CD94/NKG2 NK cell receptor, has been determined to 2.6 A resolution, revealing a unique variation of the C-type lectin fold. In this variation, the second alpha helix, corresponding to residues 102-112, is replaced by a loop, the putative carbohydrate-binding site is significantly altered, and the Ca2+-binding site appears nonfunctional. This structure may serve as a prototype for other NK cell receptors such as Ly-49, NKR-P1, and CD69. The CD94 dimer observed in the crystal has an extensive hydrophobic interface that stabilizes the loop conformation of residues 102-112. The formation of this dimer reveals a putative ligand-binding region for HLA-E and suggests how NKG2 interacts with CD94. (+info)

Differential expression of the mRNA for the vanilloid receptor subtype 1 in cells of the adult rat dorsal root and nodose ganglia and its downregulation by axotomy. (3/6088)

Sensitivity to the pungent vanilloid, capsaicin, defines a subpopulation of primary sensory neurons that are mainly polymodal nociceptors. The recently cloned vanilloid receptor subtype 1 (VR1) is activated by capsaicin and noxious heat. Using combined in situ hybridization and histochemical methods, we have characterized in sensory ganglia the expression of VR1 mRNA. We show that this receptor is almost exclusively expressed by neurofilament-negative small- and medium-sized dorsal root ganglion cells. Within this population, VR1 mRNA is detected at widely varying levels in both the NGF receptor (trkA)-positive, peptide-producing cells that elicit neurogenic inflammation and the functionally less characterized glial cell line-derived neurotrophic factor-responsive cells that bind lectin Griffonia simplicifolia isolectin B4 (IB4). Cells without detectable levels of VR1 mRNA are found in both classes. A subpopulation of the IB4-binding cells that produce somatostatin has relatively low levels of VR1 mRNA. A previously uncharacterized population of very small cells that express the receptor tyrosine kinase (RET) and that do not label for trkA or IB4-binding has the highest relative levels of VR1 mRNA. The majority of small visceral sensory neurons of the nodose ganglion also express VR1 mRNA, in conjunction with the BDNF receptor trkB but not trkA. Axotomy results in the downregulation of VR1 mRNA in dorsal root ganglion cells. Our data emphasize the heterogeneity of VR1 mRNA expression by subclasses of small sensory neurons, and this may result in their differential sensitivity to chemical and noxious heat stimuli. Our results also indicate that peripherally derived trophic factors may regulate levels of VR1 mRNA. (+info)

Control of metastasis by Asn-linked, beta1-6 branched oligosaccharides in mouse mammary cancer cells. (4/6088)

Studies in cell lines and malignant human tissues have shown that increased cell-surface Asn-linked beta1-6(GlcNAcbeta1-6Man) branching is associated with increased tumorigenic and metastatic properties. In this study, three mouse mammary cancer cell lines were transfected with an expression vector containing the mouse cDNA for N-acetylglucosaminyltransferase V (GlcNAcT-V EC 2.4.1.155), the glycosyltransferase responsible for initiating beta1-6 branching on Asn-linked carbohydrates. The cell lines were screened for increased cytotoxicity to L-PHA, a lectin specific for beta1-6 branching structures. Cell lines exhibiting increased L-PHA cytotoxicity expressed increased levels of beta1-6 branching structures. Northern blots detected the presence of GlcNAcT-V transcribed from the expression vector in the L-PHA sensitive cell lines. After injection into the tail veins of mice, transfected cell lines with increased beta1-6 branching on the cell surface formed elevated levels of lung tumors relative to control transfected cell lines (P < 0.002). Western blots of membrane proteins from GlcNAcT-V transfected and control cells probed with the lectins DSA and WGA did not show an increase in polyN-acetyllactosamine and sialic acid content in the transfected cell lines. These results demonstrate that a specific increase in beta1-6 branching due to an elevation in GlcNAcT-V expression increases metastatic potential. (+info)

Lectin receptor sites on rat liver cell nuclear membranes. (5/6088)

The presence and localization of lectin receptor sites on rat liver cell nuclear and other endomembranes was studied by light and electron microscopy using fluorescein and ferritin-coupled lectin conjugates. Isolated nuclei labelled with fluorescein-conjugated Concanavalin A (Con A) or wheat germ agglutinin (WGA) often showed membrane staining, which sometimes was especially bright on small stretches of the nuclear surface. Unlabelled nuclei and nuclei with a complete ring fluorescence were also seen. The nuclear fluorescence corresponded in intensity to that seen on the surface of isolated rat liver cells. Con A-ferritin particles were seldom detected on the cytoplasmic surface of the intact nuclear envelope. However, at places where the 2 leaflets of the envelope were widely separated or where the outer nuclear membrane was partly torn away, heavy labelling was seen on the cisternal surface of both the inner and outer nuclear membranes. Labelling with Con A-ferritin was also found on the cisternal side of rough endoplasmic reticulum present in the specimens. No labelling was seen on the cytoplasmic surface of mitochondrial outer membrane. The results demonstrate the presence of binding sites for Con A and WGA in nuclei and an asymmetric localization of these sites on the cisternal side of ribosome-carrying endomembranes in rat liver cells. (+info)

Developmental changes in mucosubstances revealed by immunostaining with antimucus monoclonal antibodies and lectin staining in the epithelium lining the segment from gizzard to duodenum of the chick embryo. (6/6088)

The mucosubstances in the epithelium lining the segment from gizzard to duodenum during development of the chick embryo was studied histochemically using monoclonal antibodies against gizzard mucus and lectins, with attention to the regional differentiation of the epithelium in this segment. The anterior limit of epithelial CdxA mRNA expression detected by in situ hybridisation, which served as the position of the gizzard-duodenal boundary, was clearly found from d 3. Granules positive for some antibodies or lectins were found in the region ranging from the posterior part of the gizzard to the duodenum at d 3, which was followed by an increase in the number of granules and a gradual enlargement of the granule-positive area to the anterior part of the gizzard over 4-6 d. From d 4, the epithelia of the gizzard body and of the pyloric or duodenal region came to be differently stained with some antibodies or lectins. From d 10, each region showed a specific pattern of staining. The epithelia of the gizzard body and pyloric region contained abundant mucus granules with a different staining pattern. In the duodenum the number of stained granules was low except in occasional goblet cells. Thus the epithelia of the gizzard body, pyloric region and duodenum may produce different mucosubstances and the regional differentiation in these epithelia may start at rather early stages soon after the formation of digestive tube. (+info)

Effect of sodium butyrate on lymphocyte activation. (7/6088)

Butyrate, in relatively low concentrations, has been shown to induce synthesis of enzymes, cause changes in cell morphology, and inhibit growth of a variety of mammalian cells in tissue culture (reviewed in [1]). In this communication, we report our observations on the effect of butyrate on lymphocyte activation. Butyrate completely and reversibly inhibits mitogen-induced blast formation. We present evidence that it does not interfere with the binding of mitogens, that it does not inhibit a number of the "early" reactions involved in activation, and that it does not affect ongoing DNA synthesis for an extended period of time. However, butyrate rapidly inhibits any increase in the rate of DNA synthesis. (+info)

In vivo NGF deprivation reduces SNS expression and TTX-R sodium currents in IB4-negative DRG neurons. (8/6088)

Recent evidence suggests that changes in sodium channel expression and localization may be involved in some pathological pain syndromes. SNS, a tetrodotoxin-resistant (TTX-R) sodium channel, is preferentially expressed in small dorsal root ganglion (DRG) neurons, many of which are nociceptive. TTX-R sodium currents and SNS mRNA expression have been shown to be modulated by nerve growth factor (NGF) in vitro and in vivo. To determine whether SNS expression and TTX-R currents in DRG neurons are affected by reduced levels of systemic NGF, we immunized adult rats with NGF, which causes thermal hypoalgesia in rats with high antibody titers to NGF. DRG neurons cultured from rats with high antibody titers to NGF, which do not bind the isolectin IB4 (IB4(-)) but do express TrkA, were studied with whole cell patch-clamp and in situ hybridization. Mean TTX-R sodium current density was decreased from 504 +/- 77 pA/pF to 307 +/- 61 pA/pF in control versus NGF-deprived neurons, respectively. In comparison, the mean TTX-sensitive sodium current density was not significantly different between control and NGF-deprived neurons. Quantification of SNS mRNA hybridization signal showed a significant decrease in the signal in NGF-deprived neurons compared with the control neurons. The data suggest that NGF has a major role in the maintenance of steady-state levels of TTX-R sodium currents and SNS mRNA in IB4(-) DRG neurons in adult rats in vivo. (+info)

Nine types of collectins have been defined: MBL = mannan-binding lectin (mannose-binding lectin) SP-A = surfactant protein A SP ... which participate in activation of the lectin pathway. MASP-2 has a cleavage activity and it is essential for forming lectin C3 ... Collectins (collagen-containing C-type lectins) are a part of the innate immune system. They form a family of collagenous Ca2+- ... Collectin MBL is involved in activation of the lectin complement pathway. There are three serine proteases, MASP-1, 2 and 3 ( ...

https://en.wikipedia.org/wiki/Collectin

... is a plant-based lectin, but not a legume lectin, found in jackfruit. It has been studied for capturing O-glycoproteins ... Jacalin belongs to a family of galactose-binding lectins containing the Jacalin-like lectin domain and it has a tetrameric two- ... The lectin is blood group non-specific after neuraminidase treatment and agglutinates human erythrocytes at a concentration of ... The relative affinities of the lectin for galactose derivatives, as well as the structural basis of its T-antigen specificity, ...

https://en.wikipedia.org/wiki/Jacalin

The name lectin is a bit misleading because the family includes proteins with at least one C-type lectin domain (CTLD) which is ... DC‑associated C‑type lectin 1 (Dectin1) subfamily includes dectin 1/CLEC7A, DNGR1/CLEC9A, Myeloid C‑type lectin‑like receptor ( ... associating lectin (MDL)‑1 (CLEC5A), DC‑associated C‑type lectin 1 (Dectin1) subfamily, and DC immunoreceptor (DCIR) subfamily ... One very important collectin is mannan-binding lectin (MBL), a major PRR of the innate immune system that binds to a wide range ...

https://en.wikipedia.org/wiki/Pattern_recognition_receptor

Mannan-binding lectins. Other assumptions may help to explain this resistance to FCoV infections by kittens. In the first weeks ... ACE and DC-SIGN are two trans-membrane retrovirus receptors (mannose receptors) which can bind "the plant lectins C-type ... Extensive data also shows that processes using sialic acid are directly involved in the interaction with the receptor's lectins ... Lozach, Pierre-Yves; Burleigh, Laura; Staropoli, Isabelle; Amara, Ali (2007). "The C Type Lectins DC-SIGN and L-SIGN". ...

https://en.wikipedia.org/wiki/Feline_coronavirus

Varki A, Cummings RD, Esko JD, Freeze HH, Stanley P, Bertozzi CR, Hart GW, Etzler M (2009). "P-type Lectins". Essentials of ... Imperial College Lectins Research Information UniProtKB/ Swiss-Prot entry for the human cation-independent mannose 6-phosphate ...

https://en.wikipedia.org/wiki/Mannose_6-phosphate_receptor

... can "hide" mannose antigens on the surface of host cells or bacteria from mannose-binding lectin.[citation needed] ... This finding is moreover supported by recent lectin staining studies and a molecular level survey on prokaryotic nonulosonic ... Mandal, C. (1990). "Sialic acid binding lectins". Experientia. 46 (5): 433-441. doi:10.1007/BF01954221. PMID 2189746. S2CID ...

https://en.wikipedia.org/wiki/Sialic_acid

During the 1940s, Boyd and Karl O. Renkonen independently discovered that lectins react differently to various blood types, ... Espino-Solis, Gerardo Pavel (April 2015). "Lectins: A brief review". Vitae. 22 (1): 9-11. doi:10.17533/udea.vitae.v22n1a01. ...

https://en.wikipedia.org/wiki/Archaeogenetics

It does this with lectin-a protein made for binding proteins-named regenectin, which shares a family with other ... Kubo T, Arai T (September 1996). "Insect Lectins and Epimorphosis". Trends in Glycoscience and Glycotechnology. 8 (43): 357-364 ... Kubo T, Arai T (September 1996). "Insect Lectins and Epimorphosis". Trends in Glycoscience and Glycotechnology. 8 (43): 357-364 ...

https://en.wikipedia.org/wiki/Epimorphosis

V. Horoejsí, O. Chaloupecká, and j. Kocourek, Studies on lectins: XLIII. Isolation and characterization of the lectin from ...

https://en.wikipedia.org/wiki/Glycopolymer

ISBN 978-0-12-385968-6. Csaba, György (September 2016). "Lectins and Tetrahymena - A review". Acta Microbiologica et ...

https://en.wikipedia.org/wiki/Tetrahymena

While some companies were considering growing GM crops expressing lectin, GNA was an unlikely candidate. Lectin is toxic, ... Vasconcelos IM, Oliveira JT (September 2004). "Antinutritional properties of plant lectins". Toxicon. 44 (4): 385-403. doi: ... "Effect of diets containing genetically modified potatoes expressing Galanthus nivalis lectin on rat small intestine". Lancet. ... allowing the tuber to synthesise the GNA lectin protein. ...

https://en.wikipedia.org/wiki/Genetically_modified_food_controversies

Another study suggests that C-type lectins part of the mannose receptor (MR) family play a role as an alternative SRLV receptor ... The mannose receptor is a 180-kDa transmembrane protein with eight tandem C-type lectin carbohydrate recognition domains (CRD) ... Kerrigan AM, Brown GD (2009). "C-type lectins and phagocytosis". Immunobiology. 214 (7): 562-575. doi:10.1016/j.imbio.2008.11. ...

https://en.wikipedia.org/wiki/Visna-maedi_virus

Cytotoxic lectins including modeccin act in a similar manner as ricin, a well understood toxic lectin, though each one has a ... Modeccin is a toxic lectin, a group of glycoproteins capable of binding specifically to sugar moieties. Different toxic lectins ... Cytotoxic lectins include ricin, abrin, modeccin, volkensin (least toxic, 10 and 40 times less cytotoxic than ricin and ... Olsnes S, Pihl A (1982). "Toxic lectins and related proteins". In Cohen P, Van Heyningen S (eds.). Molecular action of toxins ...

https://en.wikipedia.org/wiki/Modeccin

Hartley MR, Lord JM (September 2004). "Cytotoxic ribosome-inactivating lectins from plants". Biochimica et Biophysica Acta (BBA ...

https://en.wikipedia.org/wiki/Enzyme_inhibitor

C-type lectin-like receptors (CLRs) contain one or more C-type lectin (Ca2+ dependent carbohydrate-binding lectin) domains. ... C-Type Lectins in Immune Homeostasis. Current Topics in Microbiology and Immunology. 429: 103-115. doi:10.1007/82_2020_203. ... distinguished by extracellular regions containing immunoglobulin or C-type lectin domains. Nomenclature within these families ... region may contain multiple repeating protein domains and may be members of either the immunoglobulin or C-type lectin families ...

https://en.wikipedia.org/wiki/Paired_receptors

In general, lectins are used in blood typing and serology, and they are widely used in affinity chromatography for purifying ... Clavaria zollingeri contains lectins, a class of proteins that bind specific carbohydrates on the surface of cells, causing ... ISBN 978-81-85041-73-5. Jeune-Chung KH, Kim MK, Chung SR (1987). "Studies on lectins from mushrooms II. Screening of bioactive ... substance lectins from Korean wild mushrooms". Yakhak Hoeji (in Korean). 31 (4): 213-8. "Clavaria zollingeri Lév". NERI - The ...

https://en.wikipedia.org/wiki/Clavaria_zollingeri

Jeune-Chung KH, Kim MK, Chung SR (1987). "Studies on lectins from mushrooms II. Screening of bioactive substance lectins from ...

https://en.wikipedia.org/wiki/Lactifluus_volemus

Sialic acid-binding Ig-like lectin 6 is a protein that in humans is encoded by the SIGLEC6 gene. The gene was originally named ... Sialic acid-binding immunoglobulin superfamily lectins". Journal of Biological Chemistry. 275 (12): 8625-32. doi:10.1074/jbc. ...

https://en.wikipedia.org/wiki/SIGLEC6

"Ask the Expert: Clearing Up Lectin Misconceptions". Today's Dietitian Magazine. 2017. Retrieved August 14, 2018. The lectin- ... The Plant Paradox Quick and Easy: The 30-Day Plan to Lose Weight, Feel Great, and Live Lectin-Free. New York: Harper Wave. 2019 ... He is best known for his disputed claims that lectins, a type of plant protein found in numerous foods, cause inflammation ... In 2022, he authored Unlocking the Keto Code which promotes a lectin-free ketogenic diet consisting of goat and sheep dairy ...

https://en.wikipedia.org/wiki/Steven_Gundry

She characterized several lectins, including Vicia graminea lectin which is specific for human N blood group antigen, described ... Duk, M.; Lisowska, E.; Wu, J. H.; Wu, A. M. (1994-09-01). "The Biotin/Avidin-Mediated Microtiter Plate Lectin Assay with the ... Wu, Albert M.; Lisowska, Elwira; Duk, Maria; Yang, Zhangung (2008-03-27). "Lectins as tools in glycoconjugate research". ... Wu, Albert; Lisowska, Elwira; Duk, Maria; Zhangung, Yang (2009). "Lectins as tools in glycoconjugate research". Glycocnjugate ...

https://en.wikipedia.org/wiki/Elwira_Lisowska

These foods contain the highly toxic lectin phytohemagglutinin, making as few as four raw beans toxic. This lectin is only ... Among the lectins known to have toxic effects is phytohaemagglutinin which occurs at relatively high levels in the seeds of ... Kotifani, Aislinn (2020-03-06). "The Truth About Lectins-Why Beans Have Gotten a Bad Rap - Blue Zones". Blue Zones. Retrieved ... Pressure cooking also deactivates the lectins. Cooking portal Food portal Beanpot Carry over cooking Combi steamer Haybox List ...

https://en.wikipedia.org/wiki/Slow_cooker

... structure World of Lectin, Gateway to lectins Proteopedia 1bxh con A in complex with methyl alpha1-2 ... and carbohydrate-binding specificity of lectins". In Liener, Irvin E.; Sharon, Nathan; Goldstein, Irwin J. (eds.). The Lectins ... Like most lectins, ConA is a homotetramer: each sub-unit (26.5kDa, 235 amino-acids, heavily glycated) binds a metallic atom ( ... ConA was the first lectin to be available on a commercial basis, and is widely used in biology and biochemistry to characterize ...

https://en.wikipedia.org/wiki/Concanavalin_A

"Lectin from Peanuts". Sigma Aldrich. 2015. Retrieved 30 April 2015. "AABB". AABB. 2015. Retrieved 29 April 2015. Marcela ... Armed Forces Medical College, Pune Immunohaematology American Association of Blood Banks Lectin India portal Medicine portal ... The King of Lectins and Polyagglutination. In 1961, when Queen Elizabeth II visited India, Gregory Bird was in charge of ...

https://en.wikipedia.org/wiki/George_William_Gregory_Bird

... (also BanLec-I or Banana lectin) is a lectin from the jacalin-related lectin family isolated from the fruit of the ... Crystal structures of BanLec suggest that the lectin has two saccharide binding sites. In 2010, BanLec was reported to be a ... Swanson MD, Winter HC, Goldstein IJ, Markovitz DM (March 2010). "A Lectin Isolated from Bananas Is a Potent Inhibitor of HIV ... The protein is highly stable, unfolding only at high temperatures All jacalin-related lectins feature type I beta-prism folding ...

https://en.wikipedia.org/wiki/BanLec

Gupta GS (2012). Gupta GS (ed.). Animal Lectins: Form, Function and Clinical Applications. Wien: Springer-Verlag. doi:10.1007/ ... The asialoglycoprotein receptors (ASGPR) are lectins which bind asialoglycoprotein and glycoproteins from which a sialic acid ... and was the first mammalian lectin identified. The researchers transferred radioactively-labeled ceruloplasmin that had ... C-type lectins, All stub articles, Biochemistry stubs). ...

https://en.wikipedia.org/wiki/Asialoglycoprotein_receptor

Dectin-2 is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded protein is a type II ... Dectin-2 is a member of C-type lectin receptor family, which is a group of pattern recognition receptors involved in antifungal ... Dectin-2 or C-type lectin domain containing 6A is a protein that in humans is encoded by the CLEC6A gene. ... Kerscher B, Willment JA, Brown GD (May 2013). "The Dectin-2 family of C-type lectin-like receptors: an update". International ...

https://en.wikipedia.org/wiki/CLEC6A

Vautier S, Sousa M, Brown GD (December 2010). "C-type lectins, fungi and Th17 responses". Cytokine & Growth Factor Reviews. 21 ...

https://en.wikipedia.org/wiki/T_helper_17_cell

While some lectins such as cyanovirin and Urtica dioica agglutinin are thought likely to be too allergenic to be used ... Li Y, Zhang X, Chen G, Wei D, Chen F (2008). "Algal lectins for potential prevention of HIV transmission". Current Medicinal ... Huskens D, Schols D (July 2012). "Algal lectins as potential HIV microbicide candidates". Marine Drugs. 10 (7): 1476-97. doi: ... Ziółkowska NE, Wlodawer A (2006). "Structural studies of algal lectins with anti-HIV activity". Acta Biochimica Polonica. 53 (4 ...

https://en.wikipedia.org/wiki/Scytovirin

Lectins from D. confragosa, tested against rabbit and human erythrocytes, were determined to have anti-H serological ... Pemberton R.T. (1994). "Agglutinins (lectins) from some British higher fungi". Mycological Research. 98 (3): 277-90. doi: ...

https://en.wikipedia.org/wiki/Daedaleopsis_confragosa

Lectin affinity chromatography is a form of affinity chromatography where lectins are used to separate components within the ... Lectins, such as concanavalin A are proteins which can bind specific alpha-D-mannose and alpha-D-glucose carbohydrate molecules ... Another example of a lectin is wheat germ agglutinin which binds D-N-acetyl-glucosamine. The most common application is to ... Although there are various ways to perform lectin affinity chromatography, the goal is extract a sugar ligand of the desired ...

https://en.wikipedia.org/wiki/Affinity_chromatography

Some lectins are poisonous, such as the ones found in kidney beans. This is why certain foods must be soaked to hydrolyse the ...

https://everything2.com/title/lectin

Mannose-binding lectin deficiency is a condition that affects the immune system. Explore symptoms, inheritance, genetics of ... Functional mannose-binding lectins are made up of two to six protein groups called trimers, which are each composed of three of ... Mannose-binding lectin plays an important role in the bodys immune response by attaching to foreign invaders such as bacteria ... Mannose-binding lectin deficiency is a condition that affects the immune system. People with this condition have low levels ( ...

https://medlineplus.gov/genetics/condition/mannose-binding-lectin-deficiency

Dear collegues, I am loking any informaton conserning lectin or lectin-contained medicaments which are available on the market ... Lectin medicaments. Dr.A.V.Timoshenko Timoshenko at phys.bsu.unibel.by Wed Jun 17 06:14:17 EST 1998 *Previous message: BIOSCI/ ...

http://bio.net/hypermail/GLYCOSCI/1998-June/001238.html

Lectins. <. >", "path": "https://www.betternutrition.com/diet-and-nutrition/are-beans-a-nutritional-friend-or-foe/", "listing_ ...

https://www.betternutrition.com/tag/lectins/

... Br J Nutr. 1993 Jul;70(1):313-21. ... As a result of their binding and endocytosis by the epithelial cells of the small intestine, all three lectins were growth ... as the presence of this lectin in the diet may harm higher animals at the concentrations required to be effective against most ...

https://pubmed.ncbi.nlm.nih.gov/8399111/?dopt=AbstractPlus

C-type lectin superfamily member 10. DC-associated C-type lectin 2. dectin 2. dendritic cell-associated C-type lectin 2. ... C-type lectin domain family 6 member A. Names. C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily ... C-type lectin domain containing 6Aprovided by HGNC. Primary source. HGNC:HGNC:14556 See related. Ensembl:ENSG00000205846 MIM: ... Deciphering the molecular basis of mycobacteria and lipoglycan recognition by the C-type lectin Dectin-2. Decout A, et al. Sci ...

https://www.ncbi.nlm.nih.gov/gene/93978

Receptors, C-Type Lectin. Known as: C-Type Lectin Receptors, Lectin Receptors, C-Type, Receptors, C Type Lectin ...

https://www.semanticscholar.org/topic/Receptors%2C-C-Type-Lectin/9362041

What are lectins? Lectins are carbohydrate-binding proteins that are found in most foods. They can be harmful. Kidney beans are ... Lectins are not our enemies, and the foods Gundry prohibits are part of a science-based healthy diet. Avoiding them might lead ... In the book he describes many case reports of patients who improved on a lectin-limited diet, but he has done no studies with a ... Lectins play essential roles in human physiology. Among their many important functions, they regulate cell adhesion and are the ...

https://sciencebasedmedicine.org/the-plant-paradox-steven-gundrys-war-on-lectins/

... rye and rice all contain chitin-binding lectins similar to wheat lectin (WGA). ... All three cereals contain lectin at the periphery of embryonic roots. Similar lectins were not detected in oats and pearl ... Rice, a species only distantty related to wheat, contains a lectin that is antigenically similar to the other cereal lectins ... All three cereals contain lectin at the periphery of embryonic roots. Similar lectins were not detected in oats and pearl ...

https://greenmedinfo.com/article/barley-rye-and-rice-all-contain-chitin-binding-lectins-similar-wheat-lectin-wg

Immobilized lectins are prepared using affinity purified lectins. *Covalent attachment preserves lectin activity and minimizes ... Our agarose bound lectins are supplied at a constant concentration of lectin per ml of settled beads. The concentration for ... The technique we have developed to couple lectins to agarose beads inserts a hydrophilic spacer arm between the lectin and the ... The attachment of the lectins to the beads is carefully controlled to preserve lectin activity and minimize conformational ...

https://vectorlabs.com/products/glycobiology/agarose-bound-wheat-germ-agglutinin

More info for Superfamily b.77.3: Mannose-binding lectins. Timeline for Superfamily b.77.3: Mannose-binding lectins: * ... Superfamily b.77.3: Mannose-binding lectins appears in SCOPe 2.06. *Superfamily b.77.3: Mannose-binding lectins appears in the ... b.77.3.1: Mannose-binding lectins [51102] (7 proteins). *. b.77.3.0: automated matches [191397] (1 protein). not a true family ... Lineage for Superfamily b.77.3: Mannose-binding lectins. *Root: SCOPe 2.07 *. Class b: All beta proteins [48724] (178 folds). ...

http://scop.berkeley.edu/sunid=51101&ver=2.07

Lectins have been making a lot of headlines over the past year. What exactly are they, and do we need to avoid them? Medical ... What Are Lectins?. Lectins are a family of carbohydrate-binding proteins. Lectins are ubiquitous in the food supply, but they ... Should Lectins Be Avoided?. Garth Davis, MD, says people often ask him about this subject. "Like gluten and carbs, (lectins ... "If lectins are so poisonous, why would we see such amazing health in people whose diet is dominated by lectins?" ...

https://www.forksoverknives.com/wellness/do-vegans-need-worry-about-lectins/

The lectin-imprinted hydrogel layer sensor chips showed larger SPR signal change in response to a target lectin than ... On the other hand, the SPR signal change of the lectin-imprinted hydrogel layer chip in the presence of other lectin was very ... The larger SPR signal change was attributed to the strong affinity constant of the lectin-imprinted hydrogel layer for the ... These results suggest that molecular recognition sites for the lectin were formed within the hydrogel layers by molecular ...

https://www.nature.com/articles/s41428-017-0013-7?error=cookies_not_supported&code=2a03df92-55ca-4a91-82c6-4c1225d41766

Do high lectin plants tend to have more lectins in their roots in general?. Thank you ... Do you happen to know? "The most potent lectin against the SARS-CoV-induced cytopathicity is the mannose-specific plant lectin ... and every other lectin they tested). I havent been able to find much info about this lectin, but assume it might be more ... When these lectins induce specific white blood cells to multiply, they are known as mitogens . Many plant lectins are mitogens ...

https://dadamo.com/dangerous/2020/03/24/covid-19-stinging-nettle-lectin/?replytocom=696

The Mac-2 antigen is a galactose-specific lectin that binds IgE. Cherayil, B.J., Weiner, S.J., Pillai, S. J. Exp. Med. (1989) [ ... Immunohistochemical and in situ hybridization analysis of galectin-3, a beta-galactoside binding lectin, in the urinary system ... Human breast carcinoma cDNA encoding a galactoside-binding lectin homologous to mouse Mac-2 antigen. Oda, Y., Leffler, H., ... Carbohydrate-binding protein 35 (Mac-2), a laminin-binding lectin, forms functional dimers using cysteine 186. Woo, H.J., Lotz ...

https://www.wikigenes.org/e/gene/e/16854.html

Lectin Labs is announcing the launch of its first commercial product based on its groundbreaking, ... Carson City - Lectin Labs is announcing the launch of its first commercial product based on its groundbreaking, proprietary ... NutraLec is based on a class of proteins called lectins which, the Company has found, have the ability to bind to harmful ... The Company has been awarded six U.S. patents for its lectin technologies, and many more U.S. and international cases are ...

https://www.newhope.com/supply-news-amp-analysis/lectin-labs-launches-nutralec

... dc.contributor.author. Larvie, Mykol. ... Mannose-binding lectin (MBL), a soluble factor of the innate immune system, is a pattern recognition molecule with a number of ... Mannose-binding lectin binds to amyloid \(\beta\) protein and modulates inflammation. Journal of Biomedicine and Biotechnology ... Mannose-Binding Lectin Binds to Amyloid \(\beta\) Protein and Modulates Inflammation. en_US. ...

https://dash.harvard.edu/handle/1/10347163?show=full

The potential of the synthesized galactose analogues to act as competitive inhibitors in lectin-carbohydrate interactions is ... De novo synthesis and lectin binding studies of unsaturated carba-pyranoses† Timo Leermann,*a Oliver Block,b Michael A. L. ... novo synthesis and lectin binding studies of unsaturated carba. -pyranoses T. Leermann, O. Block, M. A. L. Podeschwa, U. ... in lectin-. carbohydrate. interactions is investigated by means of Surface Plasmon Resonance (SPR) Spectroscopy. . ...

https://pubs.rsc.org/en/content/articlelanding/2010/ob/c003597a

BGR, Dendritic Cell-Associated C-Type Lectin-1, Dendritic Cell-Associated C-Type Lectin 1, C-Type Lectin Domain Family 7, ... Member A, Lectin-Like Receptor 1, CD369 Antigen, CANDF4, SCARE2, CD369, C-Type Lectin Domain Containing 7A, C-Type Lectin ... C-Type Lectin Superfamily Member 12, DC-Associated C-Type Lectin 1, Beta-Glucan Receptor, Dectin-1, CLECSF12, DECTIN1. ... C-type lectin domain family 7 member A 1 or CLEC7A is a protein, that in the innate immune system, acts against fungal ...

https://www.prospecbio.com/clec7a-human

A range of products available for the purification of lectins and galactose binding molecules ... Examples of N-acetyl-D- glucosamine specific lectins are wheat germ agglutinin, elderberry lectin, Maackia amurensis lectin, ... Lectin Purification. G-Biosciences offer a range of products for the rapid purification of lectins, galactosidases and other ... Jacalin (Artocarpus integrifolia lectin). G-Biosciences Jacalin (Artocarpus integrifolia lectin) is isolated from the seeds of ...

https://www.gbiosciences.com/Protein-Research/Purification-Chromatography/Affinity-Purification-Resins/Lectin-Purification

Lectin Blot-Based Profiling of Salivary Fluid Glycoproteins Distinguishes Different Patterns Among Individuals. Presenting ...

https://www.aafs.org/research/lectin-blot-based-profiling-salivary-fluid-glycoproteins-distinguishes-different-patterns

An international team of scientists have engineered protein banana lectin, or BanLec, to create a new version that can fight ... Posted in News , Tagged Antiviral, BanLec, Genetic engineering, Lectin, Proteins, virus An international team of scientists ... "But its also exciting to have created it by engineering a lectin molecule for the first time, by understanding and then ... have engineered protein banana lectin, or BanLec, to create a new version that can fight off a range of viruses without ...

https://www.ddw-online.com/engineered-banana-lectin-could-become-broad-spectrum-antiviral-19955-202210/

... while lectin is a plant protein that has the ability to bin ... The key difference between leptin and lectin is that leptin is ... 3. What is Lectin. 4. Similarities Between Leptin and Lectin. 5. Side by Side Comparison - Leptin vs Lectin in Tabular Form. 6 ... What is Lectin?. Lectin is a protein which is of plant origin. They are found in high concentrations in wheat, rye, barley, ... The key difference between leptin and lectin is that leptin is a hormone secreted by fat cells, while lectin is a plant protein ...

https://www.differencebetween.com/difference-between-leptin-and-lectin/

Rabbit C Type Lectin Domain Family 3 Member B CLEC3B ELISA Kit - Gentaur.com - Product info ... CLEC10A (C-type Lectin Domain Family 10 Member A, C-type Lectin Superfamily Member 14, Macrophage Lectin 2, CD301, CLECSF13, ... CD302, ID (CD302 Antigen, C-type Lectin Domain Family 13 Member A, C-type Lectin BIMLEC, Type I Transmembrane C-type Lectin ... CD302, ID (CD302 Antigen, C-type Lectin Domain Family 13 Member A, C-type Lectin BIMLEC, Type I Transmembrane C-type Lectin ...

https://gentaur.com/enlibio/rabbit-c-type-lectin-domain-family-3-member-b-clec3b-elisa-kit-01017008146

The seed lectin from elderberry sambucus nigra l and its relationship to the two bark lectins. Meeting of The Belgian ... Isolation and characterization of a seed lectin from elderberry (Sambucus nigra L.) and its relationship to the bark lectins. ... The Neu Ac(-2,6)-Gal/Gal Nac-Binding Lectin from Elderberry ( Sambucus Nigra ) Bark, a type-2 Ribosome-Inactivating Protein ... The NeuAc(alpha-2,6)-Gal/GalNAc-binding lectin from elderberry (Sambucus nigra) bark, a type-2 ribosome-inactivating protein ...

https://eurekamag.com/research/040/168/040168543.php

Maackia Amurensis Lectin I (MAL I), Biotinylated (B-1315-2) by Vector Laboratories ... Lectins & Glycobiology Reagents [Lectins ], Galactose (Beta1;4) N-acetylglucosamine binding lectin. Application:. ... This lectin is the leucoagglutinin or mitogenic isolectin from Maackia seeds. Maackia amurensis lectin I binds gal (β-1,4) ... First the biotinylated lectin is added, followed by the VECTASTAIN ABC Reagent, Avidin D conjugate, or streptavidin derivative ...

https://www.2bscientific.com/Products/Vector-Laboratories/B-1315-2/Maackia-Amurensis-Lectin-I-MAL-I-Biotinylated

Home / Lectins By Latin Name / Glycine max Lectin. Glycine max Gel -SBA- Immobilized Lectin, 2mL. ... SKU: A-1301-2 Categories: Agarose Beads, Agarose Beads, Glycine max Lectin Tags: Soybean, A-1301-2, lectin, SBA, Affinity- ... Glycine max Gel -SBA- Immobilized Lectin, 2mL With the exception of Diagnostic Microbiology Products all biochemicals described ...

http://eylabs.com/product/glycine-max-gel-sba-immobilized-lectin-2ml/?add_to_wishlist=46

Understanding the role of L-type lectin receptor kinases in Phytophthora resistance: Abstract Phytophthora pathogens are ... Understanding the role of L-type lectin receptor kinases in Phytophthora resistance. Authors * Wang, Y. ... One RLK that was previously identified as a novel Phytophthora resistance component is the Arabidopsis L-type lectin receptor ... Cell death induction however, only required the kinase, not the lectin domain. Since transient expression of both LecRKs in ...

https://www.mysciencework.com/publication/show/understanding-role-l-type-lectin-receptor-kinases-phytophthora-resistance-f6e5286f?search=1

Synthesis of 3-amido-3-deoxy-beta-D-talopyranosides: all-cis-substituted pyranosides as lectin inhibitors. In: Tetrahedron. ... Synthesis of 3-amido-3-deoxy-beta-D-talopyranosides: all-cis-substituted pyranosides as lectin inhibitors. / Öberg, Christopher ... Synthesis of 3-amido-3-deoxy-beta-D-talopyranosides: all-cis-substituted pyranosides as lectin inhibitors. Tetrahedron. 2011;67 ... title = "Synthesis of 3-amido-3-deoxy-beta-D-talopyranosides: all-cis-substituted pyranosides as lectin inhibitors", ...

https://portal.research.lu.se/en/publications/synthesis-of-3-amido-3-deoxy-beta-d-talopyranosides-all-cis-subst

Lectin-Free/Plant Paradox Discussion Pt. 2 + Asking For Help + A Food Waste Tip ...

https://html5-player.libsyn.com/embed/episode/id/18261716/height/90/theme/custom/thumbnail/yes/direction/forward/render-playlist/no/custom-color/337ab7/

Lectins are a family of carbohydrate-binding proteins. (forksoverknives.com)
NutraLec is based on a class of proteins called lectins which, the Company has found, have the ability to bind to harmful bacteria and make them incapable of causing disease. (newhope.com)
Purification of N-acetyl-D-galactosamine/ D-galactose specific lectins and carbohydrate binding proteins/enzymes is consistent and affordable with N-Acetyl-D-Galactosamine Agarose . (gbiosciences.com)
N-Acetyl-D- Glucosamine Agarose is used in purification of N-acetyl-D- glucosamine specific lectins and carbohydrate binding proteins/enzymes. (gbiosciences.com)
Lectins are proteins or glycoproteins that have at least one noncatalytic domain that binds specifically and reversibly to monosaccharides or oligosaccharides. (gbiosciences.com)
Both leptin and lectin are proteins. (differencebetween.com)
Lectins are carbohydrate recognizing proteins that bind mono- and oligosaccharide specifically and reversibly but are devoid of catalytic activity. (sapub.org)
Lectins are carbohydrate-binding proteins with remarkable ability to recognize and bind reversibly to carbohydrate moieties of complex glycoconjugates without altering the covalent structure of the bound glycosyl ligands[9]. (sapub.org)
Bacterial colonization of human tissues is mediated by interaction of bacterial surface proteins - lectins - with cellular surface carbohydrates. (biomedcentral.com)
Some ANTIBODIES and carbohydrate-metabolizing proteins ( ENZYMES ) also bind to carbohydrates, however they are not considered lectins. (bvsalud.org)
PLANT LECTINS are carbohydrate-binding proteins that have been primarily identified by their hemagglutinating activity ( HEMAGGLUTININS ). (bvsalud.org)

Leptin is a hormone secreted from fat cells that helps to regulate body weight while lectin is a protein of plant origin that binds with carbohydrates. (differencebetween.com)
In contrast, lectin binds with carbohydrates and reduces the body's ability to absorb nutrients. (differencebetween.com)
Maackia amurensis lectin I binds gal (β-1,4) glcNAc but tolerates substitution of N -acetyllactosamine with sialic acid at the 3 position of galactose. (2bscientific.com)
This lectin preferably binds to [Galβ(1-4)GlcNAc, poly LacNAc] glycan epitopes. (tcichemicals.com)
Vicia villosa lectin, which binds selectively to T145 of activated T cells and which is cytotoxic for cytolytic T cell lines, has been used to select lectin-resistant mutants from these lines. (ox.ac.uk)
Included in this family is a lectin found in black locust (Robinia pseudoacacia) bark, which binds chitin but lacks chitinase activity. (unl.edu)

The root also possesses what I consider one of the most interesting plant lectins, known as Urtica Dioica Agglutinin (UDA). (dadamo.com)
Examples of N-acetyl-D-galactosamine specific lectins are lectin from Glycine max, Dolichos biflorus, Ricinus communis agglutinin, Peanut agglutinin, Jacalin etc. (gbiosciences.com)
Examples of N-acetyl-D- glucosamine specific lectins are wheat germ agglutinin, elderberry lectin, Maackia amurensis lectin, etc. (gbiosciences.com)
Both P. marinus strains bound with lower intensity to Maclura pomifera agglutinin, Bauhinia purpurea agglutinin, soybean agglutinin ( N -acetyl- d -galactosamine-specific lectins), peanut agglutinin (PNA) (terminal galactose specific), and Griffonia simplicifolia II (GlcNAc specific). (allenpress.com)
The green pea lectin (pisum sativum agglutinin) is "much less toxic" than others, according to renowned legume opponent Dr. Loren Cordain's research . (marksdailyapple.com)
The 45-kDa form was pulled down by lectin concanavalin A (Con A) and Galant husnivalis lectin (GNL), indicating an immature glycan with a high amount of mannose (Man), whereas the 65-kDa form is a mature glycan composed of acetylglucosamine (GlcNAc) and poly-N-acetyllactosame (poly-LacNAc) that was pulled down by wheat germ agglutinin (WGA) and tomato lectin, respectively. (emory.edu)

People with this condition have low levels (deficiency) of an immune system protein called mannose-binding lectin in their blood. (medlineplus.gov)
This gene provides instructions for making a protein that assembles into a complex called mannose-binding lectin. (medlineplus.gov)
Functional mannose-binding lectins are made up of two to six protein groups called trimers, which are each composed of three of the protein pieces (subunits) produced from the MBL2 gene. (medlineplus.gov)
A decrease in the availability of the normal subunit protein may lead to a reduction of the functional mannose-binding lectin in blood. (medlineplus.gov)
However, not everyone with a change in the MBL2 gene has decreased levels of mannose-binding lectin, and not everyone with decreased protein levels is prone to infection. (medlineplus.gov)
The protein encoded by this gene is a type II membrane receptor with an extracellular C-type lectin-like domain fold. (nih.gov)
Last year, Steven Gundry, MD, released The Plant Paradox: The Hidden Dangers in Healthy Foods That Cause Disease and Weight Gain , which claimed that lectins, a type of protein in many plant foods, are the culprits behind autoimmune diseases, coronary artery disease, type 2 diabetes, and a host of other health problems. (forksoverknives.com)
the authors noted that lectins such as UDA do not affect binding of the S-protein to the ACE2 receptor, but rather seem to inhibit viral entry at some undefined later stage. (dadamo.com)
C-type lectin domain family 7 member A 1 or CLEC7A is a protein, that in the innate immune system, acts against fungal pathogens. (prospecbio.com)
An international team of scientists have engineered protein banana lectin, or BanLec, to create a new version that can fight off a range of viruses without unwanted side effects. (ddw-online.com)
On the other hand, lectin is a protein that is of plant origin. (differencebetween.com)
Lectin is a protein which is of plant origin. (differencebetween.com)
In contrast, lectin is a plant protein. (differencebetween.com)
Here, using state-of-the-art structure prediction methods and structural modeling, we show that A33 has most likely evolved from a C-type lectin-like protein. (pasteur.fr)
Lectins were discovered in the last century when Stillmark (1889) presented evidence that the extreme toxicity of castor beans (Ricinus communis) could be attributed to a protein fraction which agglutinated red blood cella and which he called «ricin. (fundacionbengoa.org)
The rLSL-N is an N-terminal domain of carbohydrate-binding protein (Lectin) derived from Laetiporus sulphureus . (tcichemicals.com)
Lectin like protein whose expression is induced upon treatment with chitin oligomers. (or.jp)
The CX5 antibody is specific for mouse NKG2D (CD314, KLRK1), a lectin-like type II transmembrane receptor protein. (enquirebio.com)

The potential of the synthesized galactose analogues to act as competitive inhibitors in lectin- carbohydrate interactions is investigated by means of Surface Plasmon Resonance (SPR) Spectroscopy . (rsc.org)
G-Biosciences offer a range of products for the rapid purification of lectins, galactosidases and other galactose-binding molecules. (gbiosciences.com)
G-Biosciences Immobilized D-Galactose is for the purification of lectins, galactosidases and other galactose-, N-acetylgalactosamine- or carbohydrate binding molecules. (gbiosciences.com)
Jacalin is a α-D-galactose binding lectin consisting of a tetrameric two chain structure with a molecular weight of ~66kDa. (gbiosciences.com)
However, MAL I does not appear to bind this structure when substitution with sialic acid is on the 6 position of galactose.Biotinylated Maackia amurensis lectin has an appropriate number of biotins bound to provide the optimum staining characteristics for this lectin. (2bscientific.com)

The characterization of lectins as assailants on our health is "utter nonsense," Davis says. (forksoverknives.com)
This study explores the isolation and partial characterization of lectin from leaves of Vernonia amygdalina , Talinum triangulare, Telfairia occidentalis and the kernels of Irvingia gabonensis focusing on their degree of antibacterial activities against some selected gastrointestinal pathogenic bacteria. (sapub.org)

Understanding the role of L-type lectin receptor kinases in Ph. (mysciencework.com)
One RLK that was previously identified as a novel Phytophthora resistance component is the Arabidopsis L-type lectin receptor kinase LecRK-I.9. (mysciencework.com)
N-glycosylation of mannose receptor (CD206) regulates glycan binding by C-type lectin domains. (bvsalud.org)
The macrophage mannose receptor (MR, CD206) is a transmembrane endocytic lectin receptor, expressed in selected immune and endothelial cells , and is involved in immunity and maintaining homeostasis . (bvsalud.org)

Identification of a site on mannan-binding lectin critical for enhancement of phagocytosis. (medlineplus.gov)
We hypothesised that mannan-binding lectin (MBL) deficiency may confer risk of obesity and insulin resistance. (elsevier.com)

Ehrlich (1891) compared it with the toxic abrin from the jeriquinty seeds (Abrus precatorus) and thus initiated his immunological research on the specificity of antisera obtained by the use of these lectins. (fundacionbengoa.org)
Lectin-binding specificity was confirmed by sugar inhibition and Kolmogorov-Smirnov statistics. (allenpress.com)
Adam J, et al: Engineering of PA-IIL lectin from Pseudomonas aeruginosa - Unravelling the role of the specificity loop for sugar preference. (biomedcentral.com)

Recent progress in glycobiology has emphasized that numerous pathogens ranging from viruses and bacteria to pluricellular parasites use lectins as tools to recognize and bind to the oligosaccharides exposed by target cells and tissues[1]. (sapub.org)
PA-IIL is Pseudomonas aeruginosa tetrameric lectin, which contains two calcium ions in each binding site and recognizes fucosylated oligosaccharides [ 1 ]. (biomedcentral.com)

Relatively common mutations in the MBL2 gene can lead to mannose-binding lectin deficiency. (medlineplus.gov)
Mutations in the MBL2 gene can reduce the production of the mannose-binding lectin subunit or eliminate the subunit's ability to assemble into functional mannose-binding lectin. (medlineplus.gov)
Mannose-binding lectin concentrations, MBL2 polymorphisms, and susceptibility to respiratory tract infections in young men. (cdc.gov)
Mannose-binding lectin 2 (MBL2) gene polymorphism in asthma and atopy among adults. (cdc.gov)

This study reports on the identification of Perkinsus marinus surface carbohydrates by flow cytometric analyses of fluorescein isothiocyanate-conjugated lectin binding. (allenpress.com)

Mannose-binding lectin deficiency is a condition that affects the immune system. (medlineplus.gov)
People with mannose-binding lectin deficiency can develop infections of the upper respiratory tract and other body systems. (medlineplus.gov)
Infants and young children with mannose-binding lectin deficiency seem to be more susceptible to infections than affected adults, but adults can also develop recurrent infections. (medlineplus.gov)
Researchers believe that a number of factors, including other genetic and environmental factors, are involved in the development of mannose-binding lectin deficiency and susceptibility to infection. (medlineplus.gov)
The inheritance pattern of mannose-binding lectin deficiency is unclear. (medlineplus.gov)
It is important to note that people inherit an increased risk of developing mannose-binding lectin deficiency, not the condition itself. (medlineplus.gov)

Mannose-binding lectin (MBL), a soluble factor of the innate immune system, is a pattern recognition molecule with a number of known ligands, including viruses, bacteria, and molecules from abnormal self tissues. (harvard.edu)

however, many affected individuals have no signs or symptoms related to low mannose-binding lectin levels. (medlineplus.gov)
Mannose-binding lectin plays an important role in the body's immune response by attaching to foreign invaders such as bacteria, viruses, or yeast and turning on (activating) the complement system . (medlineplus.gov)
Mannose-binding lectin can also stimulate special immune cells to engulf and break down the attached pathogen. (medlineplus.gov)
With decreased levels of mannose-binding lectin, the body does not recognize and fight foreign invaders efficiently. (medlineplus.gov)
Effects of GNA and other mannose binding lectins on development and fecundity of the peach-potato aphid Myzus persicae. (inrae.fr)
In contrast, the collectin mannose binding lectin C (MBL-C) but not MBL-A led to efficient lectin pathway activation on A. fumigatus in the absence of ficolin-A. In addition, ficolin-A opsonization led to a modulation of the proinflammatory cytokine interleukin-8. (elsevier.com)
Eight of the ten extracellular domains of the MR are C-type lectin domains (CTLDs) which mediate the binding of mannose , fucose , and GlcNAc in a calcium -dependent manner. (bvsalud.org)
Is Plasma Level of Mannose Binding Lectin Associated With Reproductive Failure? (who.int)
Mannose-binding lectin 2 gene polymorphisms and predisposition to allergic bronchial asthma in a western Romanian children population: an observational study. (cdc.gov)
Mannose-binding lectin gene polymorphisms in infants with bronchiolitis and post-bronchiolitis wheezing. (cdc.gov)
Mannose-binding lectin genotype and serum levels in patients with chronic and allergic pulmonary aspergillosis. (cdc.gov)
Mannose binding lectin gene polymorphisms and asthma. (cdc.gov)
The role of mannose-binding lectin in pneumococcal infection. (cdc.gov)

Lectins are ubiquitous in the food supply, but they occur in especially high numbers in whole grains, legumes, potatoes, and fruit (including fruits that we typically consider vegetables, such as tomatoes and bell peppers)-in other words, a whole lot of the things that whole food, plant-based eaters rely on and enjoy every day. (forksoverknives.com)
Plant lectins like UDA probably target viral attachment and fusion, and its eventual exit (exocytosis or egress) from the cell. (dadamo.com)
A new plant lectin from elderberry (Sambucus nigra L.) bark, which was shown by immunochemical techniques to bind specifically to terminal Neu5Ac(alpha 2-6)Gal/GalNAc residues of glycoconjugates, was immobilized onto Sepharose 4B (SNA-Sepharose) and its carbohydrate binding properties was determined using a series of standard compounds. (eurekamag.com)
60. Lectin-Free/Plant Paradox Discussion Pt. (libsyn.com)
Lectins have been reported in more than 800 plant species (Lis and Sharon, 1973). (fundacionbengoa.org)
Agglutination of red blood cells by lectin from Talinum triangulare were significantly enhanced by D-lactose, D-maltose and D-glucose compared to lectin from other plant materials. (sapub.org)
The study showed that the lectins from the different plant materials were capable of inhibiting the growth of the bacterial isolates. (sapub.org)
Although some plant lectins are resistant to heat, heat processing can reduce their toxicity identified by consumption of food with high content of lectins while low temperature or insufficient cooking may be insufficient to completely eliminate them. (sapub.org)
While leguminous seeds are particularly rich sources of lectin, lectins have also been isolated from other plant families and adopted for alternative therapy[13-14]. (sapub.org)
Lectin activities in roots, nodules, stems and leaves of 1-6 week old peanut plant (A. hypogaea) were checked by erythrocyte (human and rabbit) agglutination and sugar inhibition assays. (who.int)

In plants, legume lectins are the best know lectin family[12]. (sapub.org)

Recommended product for eluting glycoconjugates bound to this agarose-lectin: Glycoprotein Eluting solution, Cat. (vectorlabs.com)
I purchased an agarose bound lectin from Vector Labs. (vectorlabs.com)
Our agarose lectin products are supplied as hydrated matrix solutions in amber glass bottles. (vectorlabs.com)
1) Draw (pipet) the desired amount of settled agarose-lectin (gel) from the stock bottle into the prepared column and let the buffer drain by gravity. (vectorlabs.com)
What are recommended conditions for using the agarose-lectin in chromatography? (vectorlabs.com)

G-Biosciences' Jacalin (Artocarpus integrifolia lectin) is isolated from the seeds of jackfruit and purified by affinity chromatography. (gbiosciences.com)

These compounds, known as "lectins" (from the Latin verb "legere," to choose), are extracted by the Company exclusively from botanical sources, many of which are present in our diet, and are being developed as nutraceutical and pharmaceutical microbicides which inhibit or destroy the infectivity of pathogenic viruses and bacteria (microbes) by binding to their carbohydrate surfaces. (newhope.com)
MBL binding to other known carbohydrate ligands is calcium-dependent and has been attributed to the carbohydrate-recognition domain, a common feature of other C-type lectins. (harvard.edu)
The carbohydrate serves as a targeting agent and newly identified fragments increase its interaction with the lectin. (biomedcentral.com)
However, a variety of lectins occur in animal species where they serve diverse array of functions through specific carbohydrate recognition. (bvsalud.org)

Although the transfer of the gene of WGA into crop plants has been advocated to increase their insect resistance, as the presence of this lectin in the diet may harm higher animals at the concentrations required to be effective against most pests, its use in plants as natural insecticide is not without health risks for man. (nih.gov)

Recombinant TC14-3 could reproduce all the activities of native lectins by itself, which was accelerated by recombinant TC14-2. (biologists.com)

A mutation in the kinase domain abolished the ability of LecRK-IX.1 and LecRK-IX.2 to induce Phytophthora resistance as did deletion of the lectin domain. (mysciencework.com)
Cell death induction however, only required the kinase, not the lectin domain. (mysciencework.com)

Saturation of bacterial surface lectins by specially designed compounds might prevent adhesion to host tissues and thus suppress the infection. (biomedcentral.com)

All of them are cytolytically active, bind up to 100-fold less lectin than the parental lines, but still express T145 or a closely related glycoprotein. (ox.ac.uk)
Lentil-lectin-purified glycoprotein antigens derived from VZV-infected human fibroblast cells (obtained through CRADA with Merck & Co.) is coated on the wells of a 96-well microtiter plate, which is subsequently incubated with a diluted test specimen. (cdc.gov)

IMSEAR at SEARO: Vegetative tissue lectins of peanut (A. hypogaea). (who.int)

This lectin is the leucoagglutinin or mitogenic isolectin from Maackia seeds. (2bscientific.com)

This conjugate is supplied essentially free of unconjugated biotins and is preserved with sodium sodium azide.This biotinylated lectin is an ideal intermediate for examining glycoconjugates using the Biotin-Avidin/Streptavidin System. (2bscientific.com)
First the biotinylated lectin is added, followed by the VECTASTAIN ABC Reagent, Avidin D conjugate, or streptavidin derivative. (2bscientific.com)

Cystic kidney cells in vitro stained positive for lectins from Concanavalia ensiformis (concanavalin A), Triticum vulgaris, Erythrina cristagalli, Ulex europeaus, and Arachis hypogaea. (cdc.gov)

He says lectins cause inflammation, stimulate weight gain, and cause leaky gut syndrome. (sciencebasedmedicine.org)
While it's true that in patients with celiac disease or gluten sensitivity, gluten (which is a type of lectin) causes inflammation that does serious long-term damage, for the vast majority of people, the fear of inflammation is overblown, Kahn says. (forksoverknives.com)

As a result of their binding and endocytosis by the epithelial cells of the small intestine, all three lectins were growth factors for the gut and interfered with its metabolism and function to varying degrees. (nih.gov)

Consequently, rLSL-N exhibits a weak hemagglutination activity to a rabbit reticulocyte through the glycan binding to subsites of the lectin. (tcichemicals.com)

Unfortunately, chickpeas contain toxins like lectins that can cause food poisoning and make you very sick if they are consumed raw, so it's important to cook them properly. (vegiac.com)

Wang, H. X. and Ng, T. B. Examination of lectins, polysaccharopeptide, polysaccharide, alkaloid, coumarin and trypsin inhibitors for inhibitory activity against human immunodeficiency virus reverse transcriptase and glycohydrolases. (webmd.com)

Some lectins are poisonous, such as the ones found in kidney beans . (everything2.com)
If lectins are so poisonous, why would we see such amazing health in people whose diet is dominated by lectins? (forksoverknives.com)

But it's also exciting to have created it by engineering a lectin molecule for the first time, by understanding and then targeting the structure. (ddw-online.com)

In investigations of the lectin pathway of complement activation, ficolin-A-opsonized conidia did not lead to lectin pathway-specific C4 deposition. (elsevier.com)

However, when UDA was exposed to the amino sugar N-acetylglucosamine the UDA lectin did not inhibit the virus infection. (dadamo.com)

Deciphering the molecular basis of mycobacteria and lipoglycan recognition by the C-type lectin Dectin-2. (nih.gov)
Molecularly imprinted hydrogel layers with lectin-recognition sites were prepared on surface plasmon resonance (SPR) sensor chips via surface-initiated atom transfer radical polymerization (SI-ATRP) combined with molecular imprinting. (nature.com)
These results suggest that molecular recognition sites for the lectin were formed within the hydrogel layers by molecular imprinting. (nature.com)
This paper describes that SI-ATRP with biomolecular imprinting is a useful method to design highly sensitive and selective SPR sensor chips with molecular recognition sites for a target lectin. (nature.com)

This complex of lectins, when applied in vitro to tunicate multipotent cells of epithelial origin, blocked cell proliferation and induced cell aggregation. (biologists.com)

Rice, a species only distantty related to wheat, contains a lectin that is antigenically similar to the other cereal lectins and located at the periphery of embryonic roots and throughut the coleoptile. (greenmedinfo.com)

Leptin and lectin are two substances. (differencebetween.com)

Identification of Cell Surface Markers to Differentiate Rat Endothelial and Fibroblast Cells Using Lectin Arrays and LC-ESI-MS/MS . Analytical Chemistry. (wisc.edu)

Antigenically similar chitin-binding lectins are present in the embryos of wheat, barley, and rye, members of the Triticeae tribe of the grass family (Gramineae). (greenmedinfo.com)
It is a member of the C-type lectin family, expressed as a disulfide-linked homodimer. (biolegend.com)
This conserved domain family includes a large number of catalytically inactive chitinase-like lectins (chitolectins) including YKL-39, YKL-40 (HCGP39), YM1, oviductin, and AMCase (acidic mammalian chitinase), as well as catalytically active chitotriosidases. (unl.edu)

Specific applications include the purification of galactosidases, C-type lectins, enterotoxins and cholera toxin. (gbiosciences.com)

Barley, rye and rice all contain chitin-binding lectins similar to wheat lectin (WGA). (greenmedinfo.com)
Lectin is absent from the coleoptile of barley but is present in the outer surface cells of this organ in wheat and in both inner and outer surface cells of rye coleoptiles. (greenmedinfo.com)

Anatomy1

Organisms19

Chemicals and Drugs50

Analytical, Diagnostic and Therapeutic Techniques and Equipment5

Phenomena and Processes11

Disciplines and Occupations2

Technology, Industry, Agriculture4

Information Science3

Lymphocyte proliferation inhibitory factor (PIF) in alcoholic liver disease. (1/6088)

Structure of CD94 reveals a novel C-type lectin fold: implications for the NK cell-associated CD94/NKG2 receptors. (2/6088)

Differential expression of the mRNA for the vanilloid receptor subtype 1 in cells of the adult rat dorsal root and nodose ganglia and its downregulation by axotomy. (3/6088)

Control of metastasis by Asn-linked, beta1-6 branched oligosaccharides in mouse mammary cancer cells. (4/6088)

Lectin receptor sites on rat liver cell nuclear membranes. (5/6088)

Developmental changes in mucosubstances revealed by immunostaining with antimucus monoclonal antibodies and lectin staining in the epithelium lining the segment from gizzard to duodenum of the chick embryo. (6/6088)

Effect of sodium butyrate on lymphocyte activation. (7/6088)

In vivo NGF deprivation reduces SNS expression and TTX-R sodium currents in IB4-negative DRG neurons. (8/6088)

Lectins

Plant Lectins

Mannose-Binding Lectins

Wheat Germ Agglutinins

Lectins, C-Type

Galectins

Glycoconjugates

Peanut Agglutinin

Carbohydrates

Concanavalin A

Galactosides

Galanthus

Acetylgalactosamine

Fetuins

Receptors, Mitogen

Hemagglutination

Carbohydrate Metabolism

Agglutination

Mannose

Carbohydrate Sequence

Canavalia

Artocarpus

Ricinus

Polysaccharides

Galactose

Ribosome Inactivating Proteins, Type 2

Hemagglutinins

Agglutinins

Hemagglutination Tests

Fucose

Asialoglycoproteins

Mannosides

Glycoproteins

Molecular Sequence Data

Acetylglucosamine

Mistletoe

Chromatography, Affinity

Ribosome Inactivating Proteins

Plants, Medicinal

Oligosaccharides

Fabaceae

N-Acetylneuraminic Acid

Receptors, N-Acetylglucosamine

Glycosylation

Methylmannosides

Abrin

Phytohemagglutinins

Amino Acid Sequence

Monosaccharides

Erythrina

Galectin 1

Histocytochemistry

Sambucus

Protein Binding

Sialic Acids

Binding Sites

Receptors, Concanavalin A

Galectin 3

Electrophoresis, Polyacrylamide Gel

Carbohydrate Conformation

Agglutination Tests

Glycosides

Collectins

Galectin 4

Castor Bean

Aralia

Sea Cucumbers

Neuraminidase

Lactose

Datura stramonium

Ricin

Liliaceae

Musa

Seeds

Soybean Proteins

Glycopeptides

Arachis hypogaea

ABO Blood-Group System

Molecular Weight

Bauhinia