Subtilisins: A family of SERINE ENDOPEPTIDASES isolated from Bacillus subtilis. EC 3.4.21.-Serine Endopeptidases: Any member of the group of ENDOPEPTIDASES containing at the active site a serine residue involved in catalysis.Matrix Metalloproteinase 15: A transmembrane domain-containing matrix metalloproteinase that plays a role in the cleavage of proteins in the pericellular environment. It is synthesized as an inactive zymogen that is activated by the action of ENDOPEPTIDASES such as MATRIX METALLOPROTEINASE 14.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Protein PrecursorsCatheter Ablation: Removal of tissue with electrical current delivered via electrodes positioned at the distal end of a catheter. Energy sources are commonly direct current (DC-shock) or alternating current at radiofrequencies (usually 750 kHz). The technique is used most often to ablate the AV junction and/or accessory pathways in order to interrupt AV conduction and produce AV block in the treatment of various tachyarrhythmias.alpha 1-Antitrypsin: Plasma glycoprotein member of the serpin superfamily which inhibits TRYPSIN; NEUTROPHIL ELASTASE; and other PROTEOLYTIC ENZYMES.Running: An activity in which the body is propelled by moving the legs rapidly. Running is performed at a moderate to rapid pace and should be differentiated from JOGGING, which is performed at a much slower pace.Cardiac Pacing, Artificial: Regulation of the rate of contraction of the heart muscles by an artificial pacemaker.Protein Processing, Post-Translational: Any of various enzymatically catalyzed post-translational modifications of PEPTIDES or PROTEINS in the cell of origin. These modifications include carboxylation; HYDROXYLATION; ACETYLATION; PHOSPHORYLATION; METHYLATION; GLYCOSYLATION; ubiquitination; oxidation; proteolysis; and crosslinking and result in changes in molecular weight and electrophoretic motility.Matrix Metalloproteinase 11: A secreted matrix metalloproteinase that is believed to play a role in EXTRACELLULAR MATRIX remodeling and cell fate determination during normal and pathological processes. Matrix metalloproteinase 11 was originally isolated in primary BREAST NEOPLASMS and may be involved in the process of tumorigenesis.Proprotein Convertase 2: A serine endopeptidase that has specificity for cleavage at ARGININE. It cleaves a variety of prohormones including PRO-OPIOMELANOCORTIN, proluteinizing-hormone-releasing hormone, proenkephalins, prodynorphin, and PROINSULIN.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Walking: An activity in which the body advances at a slow to moderate pace by moving the feet in a coordinated fashion. This includes recreational walking, walking for fitness, and competitive race-walking.Neuroendocrine Secretory Protein 7B2: An acidic protein found in the NEUROENDOCRINE SYSTEM that functions as a molecular chaperone for PROPROTEIN CONVERTASE 2.Tachycardia, Ventricular: An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).History, 20th Century: Time period from 1901 through 2000 of the common era.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.History, 21st Century: Time period from 2001 through 2100 of the common era.United StatesCervix Uteri: The neck portion of the UTERUS between the lower isthmus and the VAGINA forming the cervical canal.Aquaporin 5: Aquaporin 5 is a water-specific channel protein that is expressed primarily in alveolar, tracheal, and upper bronchial EPITHELIUM. It plays an important role in maintaining water HOMEOSTASIS in the LUNGS and may also regulate release of SALIVA and TEARS in the SALIVARY GLANDS and the LACRIMAL GLAND.Electrophysiologic Techniques, Cardiac: Methods to induce and measure electrical activities at specific sites in the heart to diagnose and treat problems with the heart's electrical system.beta-Lipotropin: A 90-amino acid peptide derived from post-translational processing of pro-opiomelanocortin (POMC) in the PITUITARY GLAND and the HYPOTHALAMUS. It is the C-terminal fragment of POMC with lipid-mobilizing activities, such as LIPOLYSIS and steroidogenesis. Depending on the species and the tissue sites, beta-LPH may be further processed to yield active peptides including GAMMA-LIPOTROPIN; BETA-MSH; and ENDORPHINS.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Molecular Probe Techniques: The use of devices which use detector molecules to detect, investigate, or analyze other molecules, macromolecules, molecular aggregates, or organisms.Sexism: Prejudice or discrimination based on gender or behavior or attitudes that foster stereotyped social roles based on gender.Chlamydia Infections: Infections with bacteria of the genus CHLAMYDIA.Biological Evolution: The process of cumulative change over successive generations through which organisms acquire their distinguishing morphological and physiological characteristics.Gait: Manner or style of walking.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Evaluation Studies as Topic: Studies determining the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies. For drugs and devices, CLINICAL TRIALS AS TOPIC; DRUG EVALUATION; and DRUG EVALUATION, PRECLINICAL are available.Pacemaker, Artificial: A device designed to stimulate, by electric impulses, contraction of the heart muscles. It may be temporary (external) or permanent (internal or internal-external).Translational Medical Research: The application of discoveries generated by laboratory research and preclinical studies to the development of clinical trials and studies in humans. A second area of translational research concerns enhancing the adoption of best practices.Diffusion of Innovation: The broad dissemination of new ideas, procedures, techniques, materials, and devices and the degree to which these are accepted and used.Phylogeny: The relationships of groups of organisms as reflected by their genetic makeup.Forecasting: The prediction or projection of the nature of future problems or existing conditions based upon the extrapolation or interpretation of existing scientific data or by the application of scientific methodology.Body Surface Potential Mapping: Recording of regional electrophysiological information by analysis of surface potentials to give a complete picture of the effects of the currents from the heart on the body surface. It has been applied to the diagnosis of old inferior myocardial infarction, localization of the bypass pathway in Wolff-Parkinson-White syndrome, recognition of ventricular hypertrophy, estimation of the size of a myocardial infarct, and the effects of different interventions designed to reduce infarct size. The limiting factor at present is the complexity of the recording and analysis, which requires 100 or more electrodes, sophisticated instrumentation, and dedicated personnel. (Braunwald, Heart Disease, 4th ed)Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Research: Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)Urbanization: The process whereby a society changes from a rural to an urban way of life. It refers also to the gradual increase in the proportion of people living in urban areas.Models, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Ventricular Premature Complexes: A type of cardiac arrhythmia with premature contractions of the HEART VENTRICLES. It is characterized by the premature QRS complex on ECG that is of abnormal shape and great duration (generally >129 msec). It is the most common form of all cardiac arrhythmias. Premature ventricular complexes have no clinical significance except in concurrence with heart diseases.Software: Sequential operating programs and data which instruct the functioning of a digital computer.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.DNA Probes: Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the DNA probe include the radioisotope labels 32P and 125I and the chemical label biotin. The use of DNA probes provides a specific, sensitive, rapid, and inexpensive replacement for cell culture techniques for diagnosing infections.Genomics: The systematic study of the complete DNA sequences (GENOME) of organisms.Health Services for the Aged: Services for the diagnosis and treatment of diseases in the aged and the maintenance of health in the elderly.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Population Dynamics: The pattern of any process, or the interrelationship of phenomena, which affects growth or change within a population.Computational Biology: A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Exercise: Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Evolution, Molecular: The process of cumulative change at the level of DNA; RNA; and PROTEINS, over successive generations.Climate: The longterm manifestations of WEATHER. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Animal Migration: Periodic movements of animals in response to seasonal changes or reproductive instinct. Hormonal changes are the trigger in at least some animals. Most migrations are made for reasons of climatic change, feeding, or breeding.Climate Change: Any significant change in measures of climate (such as temperature, precipitation, or wind) lasting for an extended period (decades or longer). It may result from natural factors such as changes in the sun's intensity, natural processes within the climate system such as changes in ocean circulation, or human activities.Algorithms: A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)E-Box Elements: DNA locations with the consensus sequence CANNTG. ENHANCER ELEMENTS may contain multiple copies of this element. E-boxes play a regulatory role in the control of transcription. They bind with basic helix-loop-helix (bHLH) type TRANSCRIPTION FACTORS. Binding specificity is determined by the specific bHLH heterodimer or homodimer combination and by the specific nucleotides at the 3rd and 4th position of the E-box sequence.Motor Activity: The physical activity of a human or an animal as a behavioral phenomenon.Sequence Analysis, DNA: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Age Factors: Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.Biomedical Technology: The application of technology to the solution of medical problems.Educational Measurement: The assessing of academic or educational achievement. It includes all aspects of testing and test construction.Nodal Protein: The founding member of the nodal signaling ligand family of proteins. Nodal protein was originally discovered in the region of the mouse embryo primitive streak referred to as HENSEN'S NODE. It is expressed asymmetrically on the left side in chordates and plays a critical role in the genesis of left-right asymmetry during vertebrate development.Sequence Alignment: The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.Reagent Kits, Diagnostic: Commercially prepared reagent sets, with accessory devices, containing all of the major components and literature necessary to perform one or more designated diagnostic tests or procedures. They may be for laboratory or personal use.beta-Endorphin: A 31-amino acid peptide that is the C-terminal fragment of BETA-LIPOTROPIN. It acts on OPIOID RECEPTORS and is an analgesic. Its first four amino acids at the N-terminal are identical to the tetrapeptide sequence of METHIONINE ENKEPHALIN and LEUCINE ENKEPHALIN.Analysis of Variance: A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Gonorrhea: Acute infectious disease characterized by primary invasion of the urogenital tract. The etiologic agent, NEISSERIA GONORRHOEAE, was isolated by Neisser in 1879.Biomedical Research: Research that involves the application of the natural sciences, especially biology and physiology, to medicine.Transfection: The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Neisseria gonorrhoeae: A species of gram-negative, aerobic bacteria primarily found in purulent venereal discharges. It is the causative agent of GONORRHEA.Great BritainAtrial Fibrillation: Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.Internationality: The quality or state of relating to or affecting two or more nations. (After Merriam-Webster Collegiate Dictionary, 10th ed)Delivery of Health Care: The concept concerned with all aspects of providing and distributing health services to a patient population.Ecosystem: A functional system which includes the organisms of a natural community together with their environment. (McGraw Hill Dictionary of Scientific and Technical Terms, 4th ed)Prevalence: The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.Defibrillators, Implantable: Implantable devices which continuously monitor the electrical activity of the heart and automatically detect and terminate ventricular tachycardia (TACHYCARDIA, VENTRICULAR) and VENTRICULAR FIBRILLATION. They consist of an impulse generator, batteries, and electrodes.Pituitary Hormones: Hormones secreted by the PITUITARY GLAND including those from the anterior lobe (adenohypophysis), the posterior lobe (neurohypophysis), and the ill-defined intermediate lobe. Structurally, they include small peptides, proteins, and glycoproteins. They are under the regulation of neural signals (NEUROTRANSMITTERS) or neuroendocrine signals (HYPOTHALAMIC HORMONES) from the hypothalamus as well as feedback from their targets such as ADRENAL CORTEX HORMONES; ANDROGENS; ESTROGENS.Genetic Variation: Genotypic differences observed among individuals in a population.Biological Clocks: The physiological mechanisms that govern the rhythmic occurrence of certain biochemical, physiological, and behavioral phenomena.Urine: Liquid by-product of excretion produced in the kidneys, temporarily stored in the bladder until discharge through the URETHRA.DNA Primers: Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.Program Evaluation: Studies designed to assess the efficacy of programs. They may include the evaluation of cost-effectiveness, the extent to which objectives are met, or impact.Polymerase Chain Reaction: In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.Clinical Trials as Topic: Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.Species Specificity: The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.Basal Metabolism: Heat production, or its measurement, of an organism at the lowest level of cell chemistry in an inactive, awake, fasting state. It may be determined directly by means of a calorimeter or indirectly by calculating the heat production from an analysis of the end products of oxidation within the organism or from the amount of oxygen utilized.Equipment Failure: Failure of equipment to perform to standard. The failure may be due to defects or improper use.EuropeGene Expression Regulation, Enzymologic: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in enzyme synthesis.Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.CHO Cells: CELL LINE derived from the ovary of the Chinese hamster, Cricetulus griseus (CRICETULUS). The species is a favorite for cytogenetic studies because of its small chromosome number. The cell line has provided model systems for the study of genetic alterations in cultured mammalian cells.Workplace: Place or physical location of work or employment.Birds: Warm-blooded VERTEBRATES possessing FEATHERS and belonging to the class Aves.Infant, Newborn: An infant during the first month after birth.Mammals: Warm-blooded vertebrate animals belonging to the class Mammalia, including all that possess hair and suckle their young.Atrioventricular Node: A small nodular mass of specialized muscle fibers located in the interatrial septum near the opening of the coronary sinus. It gives rise to the atrioventricular bundle of the conduction system of the heart.Uncertainty: The condition in which reasonable knowledge regarding risks, benefits, or the future is not available.Gene Expression Regulation, Developmental: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action during the developmental stages of an organism.Disease Progression: The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.Evidence-Based Medicine: An approach of practicing medicine with the goal to improve and evaluate patient care. It requires the judicious integration of best research evidence with the patient's values to make decisions about medical care. This method is to help physicians make proper diagnosis, devise best testing plan, choose best treatment and methods of disease prevention, as well as develop guidelines for large groups of patients with the same disease. (from JAMA 296 (9), 2006)Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Evidence-Based Practice: A way of providing health care that is guided by a thoughtful integration of the best available scientific knowledge with clinical expertise. This approach allows the practitioner to critically assess research data, clinical guidelines, and other information resources in order to correctly identify the clinical problem, apply the most high-quality intervention, and re-evaluate the outcome for future improvement.Cell Line: Established cell cultures that have the potential to propagate indefinitely.Matrix Metalloproteinases, Membrane-Associated: Matrix metalloproteinases that are associated with the CELL MEMBRANE, either through transmembrane domains or GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORS. Membrane-type matrix metalloproteinases may act within the pericellular environment to influence the process of CELL MIGRATION.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.Databases, Factual: Extensive collections, reputedly complete, of facts and data garnered from material of a specialized subject area and made available for analysis and application. The collection can be automated by various contemporary methods for retrieval. The concept should be differentiated from DATABASES, BIBLIOGRAPHIC which is restricted to collections of bibliographic references.Longitudinal Studies: Studies in which variables relating to an individual or group of individuals are assessed over a period of time.Isoenzymes: Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, but differs in its chemical, physical, or immunological characteristics.Reproduction: The total process by which organisms produce offspring. (Stedman, 25th ed)Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.Specimen Handling: Procedures for collecting, preserving, and transporting of specimens sufficiently stable to provide accurate and precise results suitable for clinical interpretation.Education, Medical: Use for general articles concerning medical education.Cross-Sectional Studies: Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.Exercise Test: Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used.Environment: The external elements and conditions which surround, influence, and affect the life and development of an organism or population.Urethra: A tube that transports URINE from the URINARY BLADDER to the outside of the body in both the sexes. It also has a reproductive function in the male by providing a passage for SPERM.Ameloblasts: Cylindrical epithelial cells in the innermost layer of the ENAMEL ORGAN. Their functions include contribution to the development of the dentinoenamel junction by the deposition of a layer of the matrix, thus producing the foundation for the prisms (the structural units of the DENTAL ENAMEL), and production of the matrix for the enamel prisms and interprismatic substance. (From Jablonski's Dictionary of Dentistry, 1992)Workload: The total amount of work to be performed by an individual, a department, or other group of workers in a period of time.Recombinant Proteins: Proteins prepared by recombinant DNA technology.Demography: Statistical interpretation and description of a population with reference to distribution, composition, or structure.Substrate Specificity: A characteristic feature of enzyme activity in relation to the kind of substrate on which the enzyme or catalytic molecule reacts.Databases, Protein: Databases containing information about PROTEINS such as AMINO ACID SEQUENCE; PROTEIN CONFORMATION; and other properties.Electrodes, Implanted: Surgically placed electric conductors through which ELECTRIC STIMULATION is delivered to or electrical activity is recorded from a specific point inside the body.Adaptation, Physiological: The non-genetic biological changes of an organism in response to challenges in its ENVIRONMENT.Biomechanical Phenomena: The properties, processes, and behavior of biological systems under the action of mechanical forces.Equipment Design: Methods of creating machines and devices.Regression Analysis: Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.Predictive Value of Tests: In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.Submandibular Gland: One of two salivary glands in the neck, located in the space bound by the two bellies of the digastric muscle and the angle of the mandible. It discharges through the submandibular duct. The secretory units are predominantly serous although a few mucous alveoli, some with serous demilunes, occur. (Stedman, 25th ed)Temperature: The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.National Institutes of Health (U.S.): An operating division of the US Department of Health and Human Services. It is concerned with the overall planning, promoting, and administering of programs pertaining to health and medical research. Until 1995, it was an agency of the United States PUBLIC HEALTH SERVICE.Body Temperature: The measure of the level of heat of a human or animal.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Education, Medical, Graduate: Educational programs for medical graduates entering a specialty. They include formal specialty training as well as academic work in the clinical and basic medical sciences, and may lead to board certification or an advanced medical degree.Dogs: The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)Proteomics: The systematic study of the complete complement of proteins (PROTEOME) of organisms.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.Sampling Studies: Studies in which a number of subjects are selected from all subjects in a defined population. Conclusions based on sample results may be attributed only to the population sampled.Oxygen Consumption: The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)Activities of Daily Living: The performance of the basic activities of self care, such as dressing, ambulation, or eating.Models, Genetic: Theoretical representations that simulate the behavior or activity of genetic processes or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.Circadian Rhythm: The regular recurrence, in cycles of about 24 hours, of biological processes or activities, such as sensitivity to drugs and stimuli, hormone secretion, sleeping, and feeding.Sex Factors: Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.DNA, Complementary: Single-stranded complementary DNA synthesized from an RNA template by the action of RNA-dependent DNA polymerase. cDNA (i.e., complementary DNA, not circular DNA, not C-DNA) is used in a variety of molecular cloning experiments as well as serving as a specific hybridization probe.Physical Education and Training: Instructional programs in the care and development of the body, often in schools. The concept does not include prescribed exercises, which is EXERCISE THERAPY.Seasons: Divisions of the year according to some regularly recurrent phenomena usually astronomical or climatic. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Research Design: A plan for collecting and utilizing data so that desired information can be obtained with sufficient precision or so that an hypothesis can be tested properly.Cricetinae: A subfamily in the family MURIDAE, comprising the hamsters. Four of the more common genera are Cricetus, CRICETULUS; MESOCRICETUS; and PHODOPUS.Data Collection: Systematic gathering of data for a particular purpose from various sources, including questionnaires, interviews, observation, existing records, and electronic devices. The process is usually preliminary to statistical analysis of the data.Proteins: Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.COS Cells: CELL LINES derived from the CV-1 cell line by transformation with a replication origin defective mutant of SV40 VIRUS, which codes for wild type large T antigen (ANTIGENS, POLYOMAVIRUS TRANSFORMING). They are used for transfection and cloning. (The CV-1 cell line was derived from the kidney of an adult male African green monkey (CERCOPITHECUS AETHIOPS).)Bone Morphogenetic Proteins: Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily of proteins. They are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.Ice Cover: A thick mass of ICE formed over large regions of land; RIVERS; LAKES; ponds; or SEAWATER.Nucleic Acid Amplification Techniques: Laboratory techniques that involve the in-vitro synthesis of many copies of DNA or RNA from one original template.Vitamin K: A lipid cofactor that is required for normal blood clotting. Several forms of vitamin K have been identified: VITAMIN K 1 (phytomenadione) derived from plants, VITAMIN K 2 (menaquinone) from bacteria, and synthetic naphthoquinone provitamins, VITAMIN K 3 (menadione). Vitamin K 3 provitamins, after being alkylated in vivo, exhibit the antifibrinolytic activity of vitamin K. Green leafy vegetables, liver, cheese, butter, and egg yolk are good sources of vitamin K.Gestational Age: The age of the conceptus, beginning from the time of FERTILIZATION. In clinical obstetrics, the gestational age is often estimated as the time from the last day of the last MENSTRUATION which is about 2 weeks before OVULATION and fertilization.Task Performance and Analysis: The detailed examination of observable activity or behavior associated with the execution or completion of a required function or unit of work.Health Policy: Decisions, usually developed by government policymakers, for determining present and future objectives pertaining to the health care system.Longevity: The normal length of time of an organism's life.Binding Sites: The parts of a macromolecule that directly participate in its specific combination with another molecule.Clinical Competence: The capability to perform acceptably those duties directly related to patient care.Helix-Loop-Helix Motifs: Recurring supersecondary structures characterized by 20 amino acids folding into two alpha helices connected by a non-helical "loop" segment. They are found in many sequence-specific DNA-BINDING PROTEINS and in CALCIUM-BINDING PROTEINS.Nursing Homes: Facilities which provide nursing supervision and limited medical care to persons who do not require hospitalization.Cloning, Molecular: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.Public Health: Branch of medicine concerned with the prevention and control of disease and disability, and the promotion of physical and mental health of the population on the international, national, state, or municipal level.Databases, Genetic: Databases devoted to knowledge about specific genes and gene products.Body Fluids: Liquid components of living organisms.Genome, Human: The complete genetic complement contained in the DNA of a set of CHROMOSOMES in a HUMAN. The length of the human genome is about 3 billion base pairs.Anti-Arrhythmia Agents: Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.Gene Expression Regulation: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.Biodiversity: The variety of all native living organisms and their various forms and interrelationships.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Sequence Homology, Amino Acid: The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.Energy Metabolism: The chemical reactions involved in the production and utilization of various forms of energy in cells.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Models, Theoretical: Theoretical representations that simulate the behavior or activity of systems, processes, or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.Molecular Sequence Annotation: The addition of descriptive information about the function or structure of a molecular sequence to its MOLECULAR SEQUENCE DATA record.Developing Countries: Countries in the process of change with economic growth, that is, an increase in production, per capita consumption, and income. The process of economic growth involves better utilization of natural and human resources, which results in a change in the social, political, and economic structures.Embryonic and Fetal Development: Morphological and physiological development of EMBRYOS or FETUSES.Physical Exertion: Expenditure of energy during PHYSICAL ACTIVITY. Intensity of exertion may be measured by rate of OXYGEN CONSUMPTION; HEAT produced, or HEART RATE. Perceived exertion, a psychological measure of exertion, is included.Genome: The genetic complement of an organism, including all of its GENES, as represented in its DNA, or in some cases, its RNA.Placenta: A highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products. It includes a fetal portion (CHORIONIC VILLI) derived from TROPHOBLASTS and a maternal portion (DECIDUA) derived from the uterine ENDOMETRIUM. The placenta produces an array of steroid, protein and peptide hormones (PLACENTAL HORMONES).Chromosome Mapping: Any method used for determining the location of and relative distances between genes on a chromosome.Feasibility Studies: Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.Metalloendopeptidases: ENDOPEPTIDASES which use a metal such as ZINC in the catalytic mechanism.Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Factor IX: Storage-stable blood coagulation factor acting in the intrinsic pathway. Its activated form, IXa, forms a complex with factor VIII and calcium on platelet factor 3 to activate factor X to Xa. Deficiency of factor IX results in HEMOPHILIA B (Christmas Disease).
He also ran a personal best of 60:56 minutes at the Great North Run, taking fifth place at the half marathon, and was the ... Pace Sport Management. Retrieved on 2013-10-28. Johnson, Len (2012-12-08). Good Bett pays off in Melbourne. IAAF. Retrieved on ... In October he was second only to Haile Gebrselassie at the Great Scottish Run and topped the podium at the Great South Run 10- ... He was a late-comer to the elite level of running and made his first professional appearances in 2010. Competing in Brazil, he ...
The 2009 mini-marathon was the 27th running of the event and took place on 1 June. It was part of a weekend of events taking ... "Fundraisers set the pace". Evening Herald. 2 June 2009. Archived from the original on 17 February 2013. Retrieved 2 June 2009 ... The 2001 mini-marathon was the 19th running of the event and took place on 4 June. More than 31,000 females took part in the ... The 2006 mini-marathon was the 23rd running of the event and took place on 6 June. Over 40,000 females took part in the race. ...
Swans Set Merry Pace to Half-Way'; The Sunday Times, 4 August 1968, p. 93 Wilkinson, Colin; 'Perth Take Over as "Cock-of-the ... East Are Run off Their Feet by Pacy South'; The Sunday Times, 1 September 1968, p. 86 Wilkinson, Colin; 'East by Three Points: ... Old Easts Run the Tigers off Their Feet'; The Sunday Times, 28 April 1968, p. 87 Perth - Biggest Home-and-Away Crowds Wilkinson ... East Fremantle End Run of Outs'; The Sunday Times, 25 August 1968, p. 88 Worner, Geoff; 'Farmer at His Artistic Best'; The ...
Bill Franques (2012-04-29). "Home Runs Pace Georgia; Baseball Tied for SEC Lead". LSUsports.net. Retrieved 2013-06-08. Seth ... Takes Game 2 with Solo Home Run". LSUsports.net. Retrieved 2013-06-08. Seth Medvin (2012-02-26). "Mountaineers Shut Down ... Seth Medvin (2012-03-18). "Five-Run First Gives MSU Baseball Series Finale". LSUsports.net. Retrieved 2013-06-08. Bill Franques ... Bill Franques (2012-03-25). "Ninth-Inning Run Lifts Baseball Past Auburn, 4-3". LSUsports.net. Retrieved 2013-06-08. Seth ...
"A Kashmiri pace bowler? Abid Nabi has begun his run-up". Indianexpress.com. 2004-11-14. Retrieved 2012-08-03. Himachal Pradesh ...
"A Kashmiri pace bowler? Abid Nabi has begun his run-up". Indianexpress.com. 2004-11-14. Retrieved 2012-08-03. "Aquib Nazir". ... "Meet Iqra Rasool: The Young Pace Bowler From Kashmir With Big Dreams". Feminism In India. 24 Feb 2017. Retrieved 24 Aug 2017. " ...
"Harper's Running Sets Florida's Pace". The Progress-Index. AP. 20 September 1964. Retrieved 4 September 2016. Moffitt, David ( ... Tennessee ran a wing-T offense that featured a running quarterback while Spurrier was an excellent passer. While Tennessee ... After two unsuccessful running plays called from the sidelines left the Gators in a third down and long situation, Coach Graves ... Henry, Ran (2014). Spurrier : how the ball coach taught the South to play football. Guilford, Connecticut: Lyons Press. ISBN ...
Clinton's running mate selection process was led by campaign chairman John Podesta and Cheryl Mills, while the vetting process ... Pace, Julie (June 21, 2016). "Hillary Clinton's VP search moves into more intense phase". Associated Press. Retrieved June 24, ... According to campaign sources, Clinton did not have a particular running mate in mind, and did not feel pressured to pick a ... Chozick, Amy (July 22, 2016). "Hillary Clinton Selects Tim Kaine, a Popular Senator From a Swing State, as Running Mate". The ...
Lemire, Jonathan; Pace, Julie (December 3, 2016). "AP: Jon Hunstman Jr. in late running for secretary of state". The Salt Lake ... Michelle Howard to run VA: report". "Donald Trump meets with another Texan, and this time it's a Lockheed Martin executive". ... Trump wants ex-Goldman partner Mnuchin to run U.S. Treasury: Fox Business, Reuters, November 3, 2016 Mnuchin Said to Be Top ... "In Donald Trump's cabinet from hell, corporatism and cronyism run rampant - and Sarah Palin may be there, too". Sarah Palin as ...
"Duke's Long Runs Stop Wake Forest". The New York Times. November 12, 1944. p. 53. Archived from the original on October 6, 2012 ... "Expect Clark To Pace Duke". St. Joseph Gazette. Durham, North Carolina. Associated Press. December 30, 1944. p. 5. Retrieved ...
Pace, Richard (21 Apr 2015). "BGR Public Relations Firm Hired By South Korea". EPR news site. EverythingPR. Gale, Alistair (21 ... Rick Kessler, a lobbyist working for BGR Group, was running for a seat in the Maryland House of Delegates in May, 2014. In 2014 ... Yeager, Holly (18 May 2014). "Lobbyists find mixed reception running for office, but a few have won elections". Washington Post ...
Average training pace: 14K/hour. Favourite race drink/food: Water/Power Bars. Running idols: "I don't idolize anyone but I ... He attempted a running comeback in the 1996 Victoria 24-hour run, but could only muster 100 kilometres in the day and night run ... Then he ran the length of Britain-1400 kilometers-in 11 days. A few months later, he ran from England through France to the ... Solo run from Winnipeg to Ottawa (2225 km). Won 24-hour race. May 1984. Ran from Toronto to Ottawa (450 km) for the 24-hour ...
The pace was kind of slow. I asked him at the quarter pole and he came running. He's a very nice horse." In his third try at ... "He ran well," said jockey Joel Rosario. "I had to move a little early and the horse that won the race was there with me and he ... The pace was very good. I had plenty of horse, so I followed the horse in front of me (Miss Temple City) and when I asked he ... Racing just behind a slow early pace, Tourist made his move around the far turn and then held off a late charge by A Lot to win ...
Hope, Clover (2005-11-24). "Brown's 'Run It!' Holds Pace At No. 1". Billboard. Nielsen Business Media, Inc. Retrieved 2009-01- ... To date, it is tied for the longest-running number-one single of the decade, and second in the entire Hot 100 era behind Boyz ... Other singles with extended chart runs include R&B singer Mario's "Let Me Love You", his best-performing song to date, and ... R&B singer Mariah Carey's "We Belong Together" is the longest-running single of 2005, topping the Billboard Hot 100 for 14 non- ...
The company is now run by his son, CEO Michael Gallo. He was the younger brother of Ernest and Julio, founders of E & J Gallo ... Eric Pace (May 4, 1993). "Julio Gallo, 83, Wine Industrialist, Dies". New York Times. Retrieved 2010-07-28. Family Secrets : ...
I get my pace from Mum... she ran the 100m in 11.6s': Swansea's Dyer reveals all". Daily Mail. 21 January 2012. Retrieved 18 ... Dyer was in fine form for much of the 2011-12 season, in which Swansea City had an impressive run for a promoted side in the ... In a 3-1 victory over Bolton Wanderers, Dyer's pace and trickery on the field were extremely effective and earned him praise ... According to Dyer, his mother could run 100 metres in 11.6 seconds. Dyer grew up supporting Manchester United because his ...
Pace is the reciprocal of speed. It can be calculated here from the following formula: p = p0·(1 + α·m) where: p = pace p0 = ... The rule has been tested on fell running times and found to be reliable. Scarf proposed this equivalence in 1998. As you can ... Also available in: ResearchGate Kay, A. (November 2012). "Pace and critical gradient for hill runners: an analysis of race ... pace on flat terrain m = gradient uphill This formula is true for m≥0 (uphill or flat terrain). It assumes equivalence of ...
Tisha Casida, a businesswoman, ran as an independent candidate. Polling External links Tisha Casida campaign website Sal Pace ... Malone, Patrick (June 1, 2011). "Pace running for 3rd Congressional District". The Pueblo Chieftain. "House Majority PAC ... who will instead run in the 4th district), all decided against running. External links Mike Coffman campaign website Joe ... On May 31, Pace declared his intention to challenge Tipton. Hoyer also suggested the name of Perry Haney, a surgeon, as a ...
Pace, Richard D (8 Oct 2015). "SKD Knickerbocker Sells To Stagwell Group For Up To $75 Million Dollars". EverythingPR. " ... O'Reilly, Bill (March 8, 2012). "Factor Investigation: Ex-Obama Official Running Sandra Fluke - Bill O'Reilly - Fox Nation". ...
records office running at hectic pace". Pittsburgh Post-Gazette. Silver, Jonathan D. (November 29, 2009). "State's records law ...
Harrison, Danny (January 28, 2016). "Jim Pace to Run for Congress". Fayette County News. Retrieved January 28, 2016. Campbell, ... former mayor of West Point Chip Flanegan Richard Mix Jim Pace Rod Thomas Withdrawn Hayden Marlowe (running for the state senate ... Carter is running unopposed. The incumbent is Democrat Sanford Bishop, who has represented the district since 1993. Bishop was ... Radio host and former Hall County Commissioner Al Gainey is considering running against Collins in the Republican primary, ...
Pace Time your passes and runs. When individuals make passes, it is important that the pace and timing of the player to receive ... We executed our game plan on the 5 Ps of football, Passing, Possession, Position, Pace, Pressure. Passing The ball can move ...
The Pakistani opening pair, Azhar Ali and Fakhar Zaman, put on 128 runs before Ali was run out for 59 runs off the last ball of ... Rajesh, S. (17 June 2017). "India's top three v Pakistan's pace". Cricinfo. Retrieved 26 June 2017. "ICC Champions Trophy, ... They lost to India in the first game by 124 runs in a sloppy display, but then defeated top-ranked South Africa by 19 runs by ... behind India on net run rate. In the semi-final, England with their undefeated run and home advantage were tipped firm ...
"Nosking Paces UM; Running Game Helps Passes". The Herald Press, Saint Joseph, Michigan (AP story). November 10, 1959. "Daring ... He had run for 23 yards in the first six games of the season and ran for 22 yards against Illinois. After Noskin's rebound ... Noskin threw a touchdown pass to Tony Rio, ran for another and set up the third with key third-down pass conversions. In its ... Noskin passed for Michigan's first score, ran for the second and set up the third with a pair of daring third-down passes." In ...
In May 2014 he won the Wings for Life World Run in Sunrise running 57.75 km and finished 27th globally. In 2015 he chose to ... Cooper, Bob (June 2, 2008). "MICHAEL WARDIAN'S CRAZY PACE". RunnersWorld. Retrieved October 16, 2008. "Wardian Wins Third ... Ungrady, Dave (October 20, 2010). "A Real Marathon Man Runs 10 a Year". On the Run. NYTimes.com. Retrieved October 21, 2010. " ... "dCRRC One Mile Track Championship (2006)". [1] 2004 Damien's Run for Recovery 5k Run Results All-Athletics. "Profile of Michael ...
As they had run out of time filming in the museum, all of the shots looking into the Pandorica were filmed three weeks later in ... this was cut due to pacing issues, which pleased Darvill as he disliked his performance in the scene.[9] Gillan stated that the ...
A Snails Pace Running Academy offers structured training to runners/walkers of all levels. Our goal is to safely train each ... A Snails Pace Running Academy is officially sponsored by BROOKS RUNNING. All participants will receive:. -a Brooks Technical ... you will receive 10% off of all purchases made at any A Snails Pace Running Shop while you are a participant of the Running ... A stronger emphasis will be placed on running form and gait.. Running 103- Fitness and 10-mile training in 36 sessions (running ...
A Snails Pace Running Academy offers a medically based, structured training program for runners/walkers of all levels. Our ... you will receive 10% off of all purchases made at any A Snails Pace Running Shop while you are a participant of the Running ... A Snails Pace Running Academy is officially sponsored by BROOKS RUNNING. All participants will receive: ... "I am the Running Academy Director for the South County Region for A Snails Pace. I cant wait to begin participating in the ...
Running a marathon and racing a marathon are vastly different. Heres how to race the 26.2-mile distance appropriately for your ... The pace band strategy is appealing because its so simple. All you have to worry about is running one simple split, over and ... The runner regroups to run what might be a better pace for about 35 minutes (the 3:40 to 4:15 mark), but at this point even ... 3 - Run that even pace until you blow up, burn out, or hit the finish line?whichever comes first. ...
Now, supply has caught up with demand and the torrid pace of sales has slowed a bit. But Reebok is still one of two solid ... But as Reebok moved into making running and court shoes, it encountered some problems. Reebok may have ``a little bit of an ... Says Jack A. Sullivan, a senior vice-president of Van Kasper & Co., a San Francisco brokerage firm: ``Its a brilliantly run ... Initial attempts to sell a high-priced Reebok running shoe in the United States failed. Later, Reebok was reorganized and ...
... you need to know how to calculate your running pace. ... or you simply want to be able to quantify your daily runs-- ... Whether you are an experienced runner trying to hit a proscribed effort for your daily run, a new runner trying to get an idea ... Calculating your running pace based on your running time and distance provides you with your average pace for the entire run ... you need to know how to calculate your running pace. The formula for figuring out your running pace is easy and you only need ...
Vazee Pace Road Running Shoes: Sleek and responsive road shoes that give a snappy, springy toe-off. The streamlined bootie ... New Balance Vazee Pace Road Running Shoes - Womens. Write a review Write a review ... New Balance Vazee Pace Road Running Shoes - Womens. 5042-970 No reviews yet. Be the first to write a review. ... Road running. Stability Some shoes include added motion control or stability features to help minimize pronation or supination ...
The NB Pace Bra for women offers medium-impact support for activities such as cycling and hiking. The convenient pullover style ... Deep Ozone Plaid NB Pace Bra (reg ) [email protected] ... The NB Pace Bra for women offers medium-impact support for activities such as cycling and hiking. The convenient pullover style ... The low-profile design, feminine details and medium-impact support of the NB Pace Bra make this fitness staple equal parts ...
... those kids can run 7-minute pace and stay aerobic) down to 5-minute aerobic pace by doing lots of running to improve some of ... but that wont help them run a marathon at 5-minute pace. Those elite runners can run 5-minute pace and chatting and laughing. ... fast paced runs in there. Most of my running was slow, easy long runs. ... How we want to run 5k faster, or 50k faster. Yes, of course, we do. But what limits your pace in endurance running is almost ...
Sport IRONMAN RUN PROGRAMME Includes Strength and Conditioning, Plyo, Warm ups and Cool downsDistance Event IRONMANSuitable for ... Find a flat course Go run as fast as you can at the most constant pace you can for 30 minutes. OR run on the track in a similar ... Run easy for 8, stay in zone 2/3, run whatever your feel comfortable distance wise, you have a lot of running to get through ... Free Run Technique Video Library on YouTube. • ALL sessions based on YOUR fitness, using HR threshold and pace for speedwork. ...
Heres everything you need to know about running to power, plus the gadgets to help you do so. ... What is running power?. Running power, measured in Watts, is a way to measure the output of the work youre doing when you run ... Garmin Running Dynamics Pods or HRM-Run/Tri. Three running accessories from Garmin track power. The dynamics pod is a belt- ... If you run a stretch of flat at 230 Watts and your pace equivalent is 8 minute miles, when that flat turns into a decent hill, ...
Ciara Mageean runs personal best time as blistering pace set in World Championship final. Ciara Mageean is embraced by Scottish ... Ciara Mageean runs personal best time as blistering pace set in World Championship final ... unprecedented pace in which the race was run.. In every World Championship final since 2007, Mageeans time would have taken ... www.belfasttelegraph.co.uk/sport/othersports/ciara-mageean-runs-personal-best-time-as-blistering-pace-set-in-world-championship ...
Heres how to work it out and some tempo runs to try. ... Your tempo pace, or lactate threshold, is a must-know for ... Warm up for 10 mins, then do a 30-min run. Start off at a pace about one min per mile slower than 10K pace, then speed up by 10 ... How to work out your tempo pace (and 4 tempo sessions to run once you know it). Your tempo pace, or lactate threshold, is a ... After a 10-min warm-up, run 15 mins at tempo pace, then 15 mins alternating 60 secs hard and 60 secs at tempo pace. By the last ...
Less experience and running at either a slow or a fast pace were risk factors for complications during 56 km road running. ... Less experience and running pace are potential risk factors for medical complications during a 56 km road running race: a ... fastest pace), gastrointestinal complications (slowest pace) and dermatological complications (fastest pace). ... running pace category. Year of observation was also associated with risk of complications (2009 vs 2008, p=0.0176; 2009 vs 2010 ...
Bike/run sessions fully up-loadable to compatible GPS devices and associated applications such as Garmin Connect, Trainer Road ... A typical week includes three swims, four bikes, and four runs. Athletes should plan on training 9-15 hours a week (peak week) ... Tags: triathlon, ironman, intermediate, masters, weightloss, time goal, multi day, hr based, pace based, tss based ... Tags: triathlon, ironman, intermediate, masters, weightloss, time goal, multi day, hr based, pace based, tss based ...
... the coveted Clarksburg Country Run 20-Mile Medal! Running through… instagram.com/p/BsoHGNxh4Uf/… ... A Change of Pace is a full-service event management and production company based in Davis, CA, located 20 miles west of ... Palo Alto Moonlight Run kicks off annual campaign to help fund child-oriented nonprofits. September 22, 2018 ... Clear skies, lots of colorful running shoes and the spirit of community were plentiful in Clarksburg this morning. # ...
The Night Nation Run is the Worlds 1st Running Music Festival an ultimate blend of a Music Festival and a Fun Run. Experience ... Northern California Running Event Calendar. Find your next NorCal running or walking event here! Race Directors: To submit a ... Calendars by Unique Event Type: Half Marathon Relay ◘ Marathon Relay ◘ Trail Run ◘ Dog Run ◘ Kids Triathlon ... Patricks Day ◘ Evening Event ◘ Beer Run ◘ July 4 ◘ Thanksgiving ◘ Christmas/Winter ◘ Womens Event ◘ Wineries/Vineyard ...
What has come as a shocking revelation that almost all central sponsered schemes are either running at a snails pace or are ... Central schemes running at snails pace in Bihar. 19 Jun 2012, 13:28 Jagran Post Editorial , Last Updated: 19 Jun 2012, 13:28 ... Patna: What has come as a shocking revelation that almost all central sponsered schemes are either running at a snails pace or ... In Pics: India Registers 197-Run Victory Against Kiwis In 500th Test ...
My form is running at a snails pace. I need it working for the event Im running now. ...
... the long runs are given more or less the same instruction, except for weeks 8, 10 and 14. The standard instruction is ... Stay below the heart rate throughout," and in week 14 its "Be VERY careful with the pace - do NOT run too fast on the running ... Generally, I guess youd recommend staying either in the Effort 1 heart rate band while running long runs(if running by heart ... or perhaps running anything up to just below Effort 2 pace? My question is, do you imagine 3h30 Plan Effort 1 pace as anything ...
... Welcome! › Forums › Running Forum › Do I run the marathon based on Pace or ... I have a question about my marathon pace.. I am running my first marathon June 12. I have run 3 long runs so far (18,20,20). ... Your pace should be that at which you ran your long training runs at if you felt tired but good at the end of them. Also, Ryan ... I would say stick with pace/effort.. As for what pace to run, your training over the next month or so will dictate a lot. ...
A Snails Pace Running Shop Group Fun Run - Monrovia June 25 @ 6:00 pm - 7:00 pm ... "A Snails Pace Running Club". They are an effective psychological tool at the races and can be purchased at A Snails Pace ... A Snails Pace Running Club, founded in 1978, is a social club designed to accommodate athletes of all abilities. You may have ... Our members run at all levels of ability, so you will always have friends to run with for training and racing! There is also a ...
A Snails Pace Running Shop Group Fun Run - Brea January 7 @ 6:00 pm - December 29 @ 8:00 pm ... The goal of the Running Academy is to create a group running environment where almost anyone can improve their level of fitness ... The ASP Running Club is Social group for all levels of runners. Members meet either at the stores or at nearby locations to go ... Without a doubt I have found my favorite store to purchase running shoes. First time here and definitely wont be my last. Mel ...
Effects Music Has on Lap Pace, Heart Rate and Perceived Exertion Rate During a 20-Minute Self-Paced Run. Submitted by: Brian C ... For trained participants, the average difference in lap pace when running to music versus running without music was just 3.03 s ... Effects Music Has on Lap Pace, Heart Rate, and Perceived Exertion Rate. During a 20-Min Self-Paced Run ... to run for 20 minutes at his own pace in the innermost lane of the three-lane track. Before beginning the run, a participant ...
In short: To get fast you have to run fast.. The problem for those who do run "fast" is that theyre typically not running fast ... and the founder of Strength Running. Have a question about running? Download the free Strength Running PR Guide to get 35+ ... and the founder of Strength Running. Have a question about running? Download the free Strength Running PR Guide to get 35+ ... Running at a pace thats only slightly faster than normal wont help you improve your performance. Even if youre training for ...
Reset the runner to the start, and run the simulation again, setting a different length stride and using a different number of ... and run the simulation again, this time using the STEP FORWARD button. Each time you click on the STEP FORWARD button, the ... attention to the graph after each run of the simulation. ... Running Races. 3-5. Students generate and compare paths which ...
  • After releasing the Moonbeam, Equator and Arc fitness trackers, the company is now launching its first watch, the Amazfit Pace. (wareable.com)
  • The State of Running 2019, by Jens Jakob Anders. (runningnetwork.com)
  • Atlanta Braves' Tyler Flowers hits a three-run home run off Philadelphia Phillies starting pitcher Zach Eflin during the fourth inning of a baseball game Wednesday, Sept. 11, 2019, in Philadelphia. (yahoo.com)
  • For example, Billat (2) reported that the coefficient of variation in velocity was 1%-5% during a 3000 m run. (sportdocbox.com)
  • And because power tracks the actual output rather than your heart's response to the work needed to produce the output, or the result of that output in speed or pace, it's possible to get a consistent reading that reflects your work rate whether you're running on the flat or uphill. (runnersworld.com)
  • Pace doesn't reflect the extra effort of running uphill or the ease of running with a tailwind or into a headwind. (runwithpower.net)
  • A Change of Pace is a full-service event management and production company based in Davis, CA, located 20 miles west of Sacramento. (changeofpace.com)
  • Since he was drafted in 2011, Jacquizz Rodgers has split duties in the backfield with Jason Snelling and either Michael Turner or Steven Jackson as the primary change-of-pace running back. (bleacherreport.com)
  • Antone Smith also has a shot to compete as a change-of-pace back as well, but the man who should run away with the job is Freeman. (bleacherreport.com)
  • the magenta is a change of pace from traditional red. (encyclopedia.com)
  • You can avoid having to calculate your pace by hand with the use of a GPS watch or speed and distance monitor. (livestrong.com)
  • If you just tell newbies to run 5 or 7 or 10 miles or whatever distance seems astronomical to them, they will automatically run slowly, won't they? (runningahead.com)
  • Once or twice a week, go on a run of at least 1.5 times your desired distance, in this case 1.5 miles. (livestrong.com)
  • When you're happy with the distance you're running, work on cutting your times by 10 to 15 seconds each run. (livestrong.com)
  • Stair running essentially elevates the heart rate while the heart and lungs pump more blood and oxygen, resulting in a higher caloric burn than doing the same distance on flat ground," explains Ryan. (rd.com)
  • Along with GPS tracking for route, distance and other stats, which looked accurate based on my tests, PACE also offers heart rate tracking, which seemed right-on to me, too. (cio.com)
  • Getting your pace right for any given distance of run is one of the hardest things to do, with failure to do so the reason for so many race-day disasters. (telegraph.co.uk)
  • 4) demonstrated that fatigue did not increase variability of velocity during a distance run (1280 m). (sportdocbox.com)
  • The M430 harnesses the latest in GPS and accelerometer technology to track your speed, distance and pace whether you're running indoors or out. (polar.com)
  • The M430 records your steps, distance, calories burned, and sleep so you can measure how the rest of your day impacts your running performance. (polar.com)
  • This is typically seen as a conservative racing strategy, but in distance events, many world records have been run with a slight negative split. (wikipedia.org)
  • Middle Distance Running. (angelfire.com)
  • The components to you running a faster middle-distance run are your VO 2 Max, efficiency of your form, speed and strength of your muscle, body composition, and how your body deals with lactic acid. (angelfire.com)
  • A good strategy allows you to conserve critical energy early, settle into a sustainable pace for the body of your race, and ideally sets you up to run the last few critical miles well. (active.com)
  • You can use various online mapping tools to map your route, estimate a road run length by driving the route in your car or run a local certified race course. (livestrong.com)
  • It wasn't enough to get past 10th place, finishing ahead of Nikki Hiltz and Winnie Nanyondo, although that's thanks to the incredible, unprecedented pace in which the race was run. (belfasttelegraph.co.uk)
  • After the race, she was gobsmacked at the pace. (belfasttelegraph.co.uk)
  • Also….should I race trying to maintain the pace…or the heart rate? (hillrunner.com)
  • No I'm not a recreational "also ran" (I race like I mean it! (hillrunner.com)
  • The shorter your race, the more anaerobic it will be since you'll be running faster. (active.com)
  • Since I can't do too much when it comes to physically training my body to be able to run the 12 hour race, I did a lot of studying. (blogspot.com)
  • If I am able to run in the efficiency zone, I would only need 25 kcal every thirty minutes in order to finish the race with barely enough energy. (blogspot.com)
  • I can't just up and run a 12 hour race. (blogspot.com)
  • If starting at a more moderate pace/effort (85%) the HR can gradually rise and keep on rising for all the race even reaching 10K effort level (90-92% of the max). (blogspot.com)
  • Finally, use RunX Fit just before a race to predict your estimated race pace - this gives you an estimate of the pace you should shoot for. (runxfit.com)
  • Perform another Pace Update Run just before your race to determine your estimated race pace. (runxfit.com)
  • Use this estimated race pace to guide your race strategy. (runxfit.com)
  • However, our 30 Minute Newbie Run gives you an estimate of your training paces so you can get started with your training right away without running a race. (runxfit.com)
  • Salmon Run -- Prepare for the race of a (fish's) lifetime! (kickstarter.com)
  • I'd run some laps around the parking lot to warm up and was hopping from foot to foot with other racers at the start line, just wishing they'd stop blaring that stupid 'Tonight's gonna be a good night' song and begin the race. (sun-sentinel.com)
  • Polar's exclusive Running Index interprets your speed and heart rate data, then delivers easy to understand insights about your current condition, likely race finish times and more. (polar.com)
  • However, in a championship race, where the goal of the racer is to win, the pace is typically slow in the beginning of the race and gradually speeds up for a sprint finish, often meaning the race is run with a negative split. (wikipedia.org)
  • The racer tries to run an "even" pace during the entire race. (wikipedia.org)
  • The racer runs slow in the beginning, and gradually runs faster as the race progresses. (wikipedia.org)
  • Because the race is so short, racers simply run at their top speed for the duration of the race. (wikipedia.org)
  • An analysis of world-record performances in these events shows a clear pattern: relatively even pacing throughout most of the race, and a slight increase in speed in the last 1000m of both the 5000m and 10000m. (wikipedia.org)
  • off the pace behind the leader or leading group in a race or contest. (encyclopedia.com)
  • The optimal ratio of muscle fiber typing is that which can propel you at the pace you need, with just enough resistance to fatigue to last the duration of the race. (angelfire.com)
  • Either side of Vettel's performance runs, Ferrari set about conducting longer stints and a full race simulation just after lunch. (go.com)
  • Pace announced that he would not seek reelection to his House district 46 seat in 2012, and would instead enter the race for Colorado's 3rd Congressional District. (wikipedia.org)
  • If you run a stretch of flat at 230 Watts and your pace equivalent is 8 minute miles, when that flat turns into a decent hill, in order to maintain a steady 230 Watts, the chances are you're going to have to slow down. (runnersworld.com)
  • Running 103- Fitness and 10-mile training in 36 sessions (running with an introduction to core and strength training exercises) This is a group course to continue your advancement in your running endurance while making your an overall stronger athlete. (meetup.com)
  • 7 AM Saturday mornings at Bonelli Park 1615 McKinley Ave, La Verne, CA 91750 (in the Norm's Hangar Parking Lot) and 6 PM Wednesday classes are at the ASP Monrovia running shop at 750 S. Myrtle, Monrovia 91016. (meetup.com)
  • Find a group of people to run with in order to keep up the pace, or chart your times against others with a fitness app . (healthline.com)
  • Running is huge and has quite a big following, but as we can see from the chart below it's declining in the last two years. (runningnetwork.com)
  • A stronger emphasis will be placed on running form and gait. (meetup.com)
  • Dr. Reed Ferber, an Alberta Innovates Health Solutions researcher who led his team, has developed a procedure of studying a person's running gait to ascertain if the alignment of the hips is right. (medindia.net)
  • CIO.com's resident reviewer, tech addict and fitness fanatic James A. Martin puts the latest apps, mobile devices, health gadgets and wearable technologies through the paces. (cio.com)
  • The streamlined bootie construction hugs your feet for a snug feel, and the heel counter flexes for more freedom in your stride as you sprint up the steep staircase on your run. (mec.ca)
  • Using your stride speed as a metronome for your breathing can become strangely hypnotic, and is a good way of keeping your mind occupied as you run. (telegraph.co.uk)
  • We often hear that shoes can last for 300 to 500 miles, but wear and tear depends on an individual's body weight, hard or soft landings with each stride, and style of running. (betternutrition.com)
  • This technique uses the same stride and muscles as running, so it helps to build a good rhythm for later running. (wikihow.com)
  • For example, if you covered five miles in 40 minutes, divide 40 minutes by five miles and get your pace of eight minutes per mile. (livestrong.com)
  • So, the problem of the mile: I can run 400 meters in 75 seconds. (runningahead.com)
  • The problem of the marathon: I can run 10 miles at 7:00 per mile. (runningahead.com)
  • For age-group competitors, it might be 10-mile or 15K pace. (runnersworld.com)
  • This is where running on a track comes in handy, as each 400M lap of the track is equal to 1/4 of a mile, so four laps of the track is equal to one mile. (wikihow.com)
  • Find a local track or flat surface of about 1/4 mile (400 meters) to run on. (wikihow.com)
  • To train for a 10-minute mile, aim to complete these runs in less than 20 minutes. (livestrong.com)
  • Maintain the pace as closely as possible, with the goal of being under 7:30 with a quarter mile to go. (livestrong.com)
  • Once you can run a 10-minute mile, it's important to continue to challenge yourself for improved fitness and results. (livestrong.com)
  • Thanks to GPS watches, we're so accustomed to seeing minutes per mile on our wrists that we've become a little brainwashed about what pace truly measures. (runwithpower.net)
  • You combine phrases like "10 Mile" and Easy Run" in the same breath. (coolrunning.com)
  • Having a goal pace will provide you with extra motivation and focus. (runxfit.com)
  • Risk factors for specific common medical complications were: postural hypotension (slowest pace), serious exercise-associated muscle cramping (older age, fastest pace), gastrointestinal complications (slowest pace) and dermatological complications (fastest pace). (nih.gov)
  • These will also provide you with your current pace throughout your run. (livestrong.com)
  • Is my current pace of a few posts a week adequate for your needs, or would you be happier if I delivered at least one new post every day? (scienceblogs.com)
  • Then there are the psychological benefits: running triggers a surge of endorphins - feel-good hormones - and increases circulation to the brain, boosting focus and alertness. (weightwatchers.com)
  • Search for '180 BPM' music on YouTube or Spotify and then run in sync with it. (weightwatchers.com)
  • Pace also reflects on an adage he recently borrowed from Ernie Accorsi, the longtime front-office executive who aided the Bears' 2015 search for a new GM and coach. (chicagotribune.com)
  • 3 - Run that even pace until you blow up, burn out, or hit the finish line?whichever comes first. (active.com)
  • Ask yourself if running is something you enjoy, since you'll be more likely to drum up the motivation for an activity you truly want to do. (healthline.com)
  • While you run, practice good form by keeping your head up with your eyes straight ahead. (wikihow.com)
  • Pacing is all about practice and repetition so that you get to know how your body feels and performs at different intensities and in different situations. (telegraph.co.uk)