Lasers: An optical source that emits photons in a coherent beam. Light Amplification by Stimulated Emission of Radiation (LASER) is brought about using devices that transform light of varying frequencies into a single intense, nearly nondivergent beam of monochromatic radiation. Lasers operate in the infrared, visible, ultraviolet, or X-ray regions of the spectrum.Lasers, Solid-State: Lasers which use a solid, as opposed to a liquid or gas, as the lasing medium. Common materials used are crystals, such as YAG (YTTRIUM aluminum garnet); alexandrite; and CORUNDUM, doped with a rare earth element such as a NEODYMIUM; ERBIUM; or HOLMIUM. The output is sometimes additionally modified by addition of non-linear optical materials such as potassium titanyl phosphate crystal, which for example is used with neodymium YAG lasers to convert the output light to the visible range.Laser Coagulation: The use of green light-producing LASERS to stop bleeding. The green light is selectively absorbed by HEMOGLOBIN, thus triggering BLOOD COAGULATION.Laser Therapy, Low-Level: Treatment using irradiation with LASER light of low power intensity so that the effects are not due to heat, as they are in LASER THERAPY.Lasers, Excimer: Gas lasers with excited dimers (i.e., excimers) as the active medium. The most commonly used are rare gas monohalides (e.g., argon fluoride, xenon chloride). Their principal emission wavelengths are in the ultraviolet range and depend on the monohalide used (e.g., 193 nm for ArF, 308 nm for Xe Cl). These lasers are operated in pulsed and Q-switched modes and used in photoablative decomposition involving actual removal of tissue. (UMDNS, 2005)Lasers, Dye: Tunable liquid lasers with organic compounds (i.e., dye) which have a strong absorption band, used as the active medium. During emission, the dye has to be optically excited by another light source (e.g., another laser or flash lamp). The range of the emission wavelength may be anywhere from the ultraviolet to the near infrared (i.e., from 180 to 1100nm). These lasers are operated in continuous wave and pulsed modes. (UMDNS, 2005)Laser Scanning Cytometry: A scanning microscope-based, cytofluorimetry technique for making fluorescence measurements and topographic analysis on individual cells. Lasers are used to excite fluorochromes in labeled cellular specimens. Fluorescence is detected in multiple discrete wavelengths and the locational data is processed to quantitatively assess APOPTOSIS; PLOIDIES; cell proliferation; GENE EXPRESSION; PROTEIN TRANSPORT; and other cellular processes.Keratomileusis, Laser In Situ: A surgical procedure to correct MYOPIA by CORNEAL STROMA subtraction. It involves the use of a microkeratome to make a lamellar dissection of the CORNEA creating a flap with intact CORNEAL EPITHELIUM. After the flap is lifted, the underlying midstroma is reshaped with an EXCIMER LASER and the flap is returned to its original position.Angioplasty, Laser: A technique utilizing a laser coupled to a catheter which is used in the dilatation of occluded blood vessels. This includes laser thermal angioplasty where the laser energy heats up a metal tip, and direct laser angioplasty where the laser energy directly ablates the occlusion. One form of the latter approach uses an EXCIMER LASER which creates microscopically precise cuts without thermal injury. When laser angioplasty is performed in combination with balloon angioplasty it is called laser-assisted balloon angioplasty (ANGIOPLASTY, BALLOON, LASER-ASSISTED).Laser Capture Microdissection: Techniques using a laser to cut away and harvest a specific cell or cluster of cells from a tissue section while viewing it under the microscope.Microscopy, Confocal: A light microscopic technique in which only a small spot is illuminated and observed at a time. An image is constructed through point-by-point scanning of the field in this manner. Light sources may be conventional or laser, and fluorescence or transmitted observations are possible.Microdissection: The performance of dissections with the aid of a microscope.Laser-Doppler Flowmetry: A method of non-invasive, continuous measurement of MICROCIRCULATION. The technique is based on the values of the DOPPLER EFFECT of low-power laser light scattered randomly by static structures and moving tissue particulates.Corneal Surgery, Laser: Surgical techniques on the CORNEA employing LASERS, especially for reshaping the CORNEA to correct REFRACTIVE ERRORS.Light Coagulation: The coagulation of tissue by an intense beam of light, including laser (LASER COAGULATION). In the eye it is used in the treatment of retinal detachments, retinal holes, aneurysms, hemorrhages, and malignant and benign neoplasms. (Dictionary of Visual Science, 3d ed)Ophthalmoscopy: Examination of the interior of the eye with an ophthalmoscope.Infrared Rays: That portion of the electromagnetic spectrum usually sensed as heat. Infrared wavelengths are longer than those of visible light, extending into the microwave frequencies. They are used therapeutically as heat, and also to warm food in restaurants.Photorefractive Keratectomy: A type of refractive surgery of the CORNEA to correct MYOPIA and ASTIGMATISM. An EXCIMER LASER is used directly on the surface of the EYE to remove some of the CORNEAL EPITHELIUM thus reshaping the anterior curvature of the cornea.Argon: Argon. A noble gas with the atomic symbol Ar, atomic number 18, and atomic weight 39.948. It is used in fluorescent tubes and wherever an inert atmosphere is desired and nitrogen cannot be used.Ophthalmoscopes: Devices for examining the interior of the eye, permitting the clear visualization of the structures of the eye at any depth. (UMDNS, 1999)Neon: Neon. A noble gas with the atomic symbol Ne, atomic number 10, and atomic weight 20.18. It is found in the earth's crust and atmosphere as an inert, odorless gas and is used in vacuum tubes and incandescent lamps.Equipment Design: Methods of creating machines and devices.Fluorescein Angiography: Visualization of a vascular system after intravenous injection of a fluorescein solution. The images may be photographed or televised. It is used especially in studying the retinal and uveal vasculature.Erbium: Erbium. An element of the rare earth family of metals. It has the atomic symbol Er, atomic number 68, and atomic weight 167.26.Fiber Optic Technology: The technology of transmitting light over long distances through strands of glass or other transparent material.Optical Fibers: Thin strands of transparent material, usually glass, that are used for transmitting light waves over long distances.Visual Acuity: Clarity or sharpness of OCULAR VISION or the ability of the eye to see fine details. Visual acuity depends on the functions of RETINA, neuronal transmission, and the interpretative ability of the brain. Normal visual acuity is expressed as 20/20 indicating that one can see at 20 feet what should normally be seen at that distance. Visual acuity can also be influenced by brightness, color, and contrast.Fetoscopy: Endoscopic examination, therapy or surgery of the fetus and amniotic cavity through abdominal or uterine entry.Dental Soldering: The joining of pieces of metal through the use of an alloy which has a lower melting point, usually at least 100 degrees Celsius below the fusion temperature of the parts being soldered. In dentistry, soldering is used for joining components of a dental appliance, as in assembling a bridge, joining metals to orthodontic bands, or adding to the bulk of certain structures, such as the establishment of proper contact areas on inlays and crowns with adjacent teeth. (Illustrated Dictionary of Dentistry, 1982)Angioplasty, Balloon, Laser-Assisted: Techniques using laser energy in combination with a balloon catheter to perform angioplasty. These procedures can take several forms including: 1, laser fiber delivering the energy while the inflated balloon centers the fiber and occludes the blood flow; 2, balloon angioplasty immediately following laser angioplasty; or 3, laser energy transmitted through angioplasty balloons that contain an internal fiber.Fundus Oculi: The concave interior of the eye, consisting of the retina, the choroid, the sclera, the optic disk, and blood vessels, seen by means of the ophthalmoscope. (Cline et al., Dictionary of Visual Science, 4th ed)Optics and Photonics: A specialized field of physics and engineering involved in studying the behavior and properties of light and the technology of analyzing, generating, transmitting, and manipulating ELECTROMAGNETIC RADIATION in the visible, infrared, and ultraviolet range.Interferometry: Measurement of distances or movements by means of the phenomena caused by the interference of two rays of light (optical interferometry) or of sound (acoustic interferometry).Cornea: The transparent anterior portion of the fibrous coat of the eye consisting of five layers: stratified squamous CORNEAL EPITHELIUM; BOWMAN MEMBRANE; CORNEAL STROMA; DESCEMET MEMBRANE; and mesenchymal CORNEAL ENDOTHELIUM. It serves as the first refracting medium of the eye. It is structurally continuous with the SCLERA, avascular, receiving its nourishment by permeation through spaces between the lamellae, and is innervated by the ophthalmic division of the TRIGEMINAL NERVE via the ciliary nerves and those of the surrounding conjunctiva which together form plexuses. (Cline et al., Dictionary of Visual Science, 4th ed)Choroid: The thin, highly vascular membrane covering most of the posterior of the eye between the RETINA and SCLERA.Equipment Failure Analysis: The evaluation of incidents involving the loss of function of a device. These evaluations are used for a variety of purposes such as to determine the failure rates, the causes of failures, costs of failures, and the reliability and maintainability of devices.Myopia: A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.Photolysis: Chemical bond cleavage reactions resulting from absorption of radiant energy.Iris: The most anterior portion of the uveal layer, separating the anterior chamber from the posterior. It consists of two layers - the stroma and the pigmented epithelium. Color of the iris depends on the amount of melanin in the stroma on reflection from the pigmented epithelium.Photochemotherapy: Therapy using oral or topical photosensitizing agents with subsequent exposure to light.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Macular Edema: Fluid accumulation in the outer layer of the MACULA LUTEA that results from intraocular or systemic insults. It may develop in a diffuse pattern where the macula appears thickened or it may acquire the characteristic petaloid appearance referred to as cystoid macular edema. Although macular edema may be associated with various underlying conditions, it is most commonly seen following intraocular surgery, venous occlusive disease, DIABETIC RETINOPATHY, and posterior segment inflammatory disease. (From Survey of Ophthalmology 2004; 49(5) 470-90)Intraocular Pressure: The pressure of the fluids in the eye.Retina: The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent.Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.Dermatologic Surgical Procedures: Operative procedures performed on the SKIN.Fluorescent Dyes: Agents that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags.Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)Microscopy, Fluorescence, Multiphoton: Fluorescence microscopy utilizing multiple low-energy photons to produce the excitation event of the fluorophore. Multiphoton microscopes have a simplified optical path in the emission side due to the lack of an emission pinhole, which is necessary with normal confocal microscopes. Ultimately this allows spatial isolation of the excitation event, enabling deeper imaging into optically thick tissue, while restricting photobleaching and phototoxicity to the area being imaged.Corneal Stroma: The lamellated connective tissue constituting the thickest layer of the cornea between the Bowman and Descemet membranes.Photons: Discrete concentrations of energy, apparently massless elementary particles, that move at the speed of light. They are the unit or quantum of electromagnetic radiation. Photons are emitted when electrons move from one energy state to another. (From Hawley's Condensed Chemical Dictionary, 11th ed)Microsurgery: The performance of surgical procedures with the aid of a microscope.Microscopy, Electron, Scanning: Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.Tomography, Optical Coherence: An imaging method using LASERS that is used for mapping subsurface structure. When a reflective site in the sample is at the same optical path length (coherence) as the reference mirror, the detector observes interference fringes.Photosensitizing Agents: Drugs that are pharmacologically inactive but when exposed to ultraviolet radiation or sunlight are converted to their active metabolite to produce a beneficial reaction affecting the diseased tissue. These compounds can be administered topically or systemically and have been used therapeutically to treat psoriasis and various types of neoplasms.Yttrium: An element of the rare earth family of metals. It has the atomic symbol Y, atomic number 39, and atomic weight 88.91. In conjunction with other rare earths, yttrium is used as a phosphor in television receivers and is a component of the yttrium-aluminum garnet (YAG) lasers.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Iridectomy: Surgical removal of a section of the iris.Retinal DiseasesScattering, Radiation: The diversion of RADIATION (thermal, electromagnetic, or nuclear) from its original path as a result of interactions or collisions with atoms, molecules, or larger particles in the atmosphere or other media. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Hair Removal: Methods used to remove unwanted facial and body hair.Skin: The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.Light: That portion of the electromagnetic spectrum in the visible, ultraviolet, and infrared range.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Surgical Flaps: Tongues of skin and subcutaneous tissue, sometimes including muscle, cut away from the underlying parts but often still attached at one end. They retain their own microvasculature which is also transferred to the new site. They are often used in plastic surgery for filling a defect in a neighboring region.Diagnostic Techniques, Ophthalmological: Methods and procedures for the diagnosis of diseases of the eye or of vision disorders.Choroidal Neovascularization: A pathological process consisting of the formation of new blood vessels in the CHOROID.Regional Blood Flow: The flow of BLOOD through or around an organ or region of the body.Micromanipulation: The performance of dissections, injections, surgery, etc., by the use of micromanipulators (attachments to a microscope) that manipulate tiny instruments.Optical Devices: Products or parts of products used to detect, manipulate, or analyze light, such as LENSES, refractors, mirrors, filters, prisms, and OPTICAL FIBERS.Retinal Vessels: The blood vessels which supply and drain the RETINA.Dissection: The separation and isolation of tissues for surgical purposes, or for the analysis or study of their structures.Varicose Veins: Enlarged and tortuous VEINS.Refractometry: Measurement of the index of refraction (the ratio of the velocity of light or other radiation in the first of two media to its velocity in the second as it passes from one into the other).Phototherapy: Treatment of disease by exposure to light, especially by variously concentrated light rays or specific wavelengths.Spectrum Analysis, Raman: Analysis of the intensity of Raman scattering of monochromatic light as a function of frequency of the scattered light.Birefringence: The property of nonisotropic media, such as crystals, whereby a single incident beam of light traverses the medium as two beams, each plane-polarized, the planes being at right angles to each other. (Cline et al., Dictionary of Visual Science, 4th ed)Optical Tweezers: A technique that uses LASERS to trap, image, and manipulate small objects (biomolecules, supramolecular assembles, DENDRIMERS) in three dimensional space. (From Glossary of Biotechnology and Nanobiotechnology Terms, 4th ed.)Optic Disk: The portion of the optic nerve seen in the fundus with the ophthalmoscope. It is formed by the meeting of all the retinal ganglion cell axons as they enter the optic nerve.Krypton: A noble gas that is found in the atmosphere. It has the atomic symbol Kr, atomic number 36, atomic weight 83.80, and has been used in electric bulbs.Wound Healing: Restoration of integrity to traumatized tissue.Nerve Fibers: Slender processes of NEURONS, including the AXONS and their glial envelopes (MYELIN SHEATH). Nerve fibers conduct nerve impulses to and from the CENTRAL NERVOUS SYSTEM.
Fluorimetric multiparameter cell assay at the single cell level fabricated by optical tweezers. (1/3679)A fluorimetric multi-parameter cell sensor at the single cell level is presented which makes it possible to observe the physiological behavior of different cell lines, different physiological parameters, and statistical data at the same time. Different cell types were immobilized at predefined positions with high accuracy using optical tweezers and adhesion promoting surface layers. The process is applicable to both adherent and non-adherent cells. Coating of the immobilization area with mussel adhesive protein was shown to be essential for the process. Intracellular proton and calcium concentrations in different cell classes were simultaneously imaged and the specific activation of T lymphocytes was demonstrated. This method should be especially useful for drug screening due to the small sample volume and high information density. (+info)
A repetitive mode of activation of discrete Ca2+ release events (Ca2+ sparks) in frog skeletal muscle fibres. (2/3679)1. Ca2+ release events (Ca2+ 'sparks'), which are believed to arise from the opening of a sarcoplasmic reticulum (SR) Ca2+ release channel or a small cluster of such channels that act as a release unit, have been measured in single, frog (Rana pipiens) skeletal muscle fibres. 2. Under conditions of extremely low rates of occurrence of Ca2+ sparks we observed, within individual identified triads, repetitive Ca2+ release events which occurred at a frequency more than 100-fold greater than the prevailing average event rate. Repetitive sparks were recorded during voltage-clamp test depolarizations after a brief (0.3-2 s) repriming interval in fibres held at 0 mV and in chronically depolarized, 'notched' fibres. 3. These repetitive events are likely to arise from the re-opening of the same SR Ca2+ release channel or release unit operating in a repetitive gating mode ('rep-mode'), rather than from the random activation of multiple, independent channels or release units within a triad. A train of rep-mode events thus represents a series of Ca2+ sparks arising from a single location within the fibre. Rep-mode events are activated among different triads in a random manner after brief repriming. The frequency of repetitive events among all identified events during voltage-clamp depolarization to 0 mV after brief repriming was 3.9 +/- 1.3 %. The occurrence of repetitive events was not related to exposure of the fibre to laser illumination. 4. The events observed within a rep-mode train exhibited a relatively uniform amplitude. Analysis of intervals between identified events in triads exhibiting rep-mode trains indicated similar variations of fluorescence as in neighbouring, quiescent triads, suggesting there was not a significant number of small, unidentified events at the triads exhibiting rep-mode activity. 5. The distribution of rep-mode interspark intervals exhibited a paucity of events at short intervals, consistent with the need for recovery from inactivation before activation of the next event in a repetitive train. The mean interspark interval of repetitive sparks during voltage-clamp depolarizations was 88 +/- 5 ms, and was independent of membrane potential. 6. The individual Ca2+ sparks within a rep-mode train were similar in average amplitude and spatiotemporal extent to singly occurring sparks, suggesting a common mechanism for termination of the channel opening(s) underlying both types of events. The average properties of the sparks did not vary during a train. The relative amplitude of a spark within a rep-mode was not correlated with its rise time. 7. Repetitive Ca2+ release events represent a mode of gating of SR Ca2+ release channels which may be significant during long depolarizations and which may be influenced by the biochemical state of the SR ryanodine receptor Ca2+ release channels. (+info)
Elimination of EVE protein by CALI in the short germ band insect Tribolium suggests a conserved pair-rule function for even skipped. (3/3679)The question of the degree of evolutionary conservation of the pair-rule patterning mechanism known from Drosophila is still contentious. We have employed chromophore-assisted laser inactivation (CALI) to inactivate the function of the pair-rule gene even skipped (eve) in the short germ embryo of the flour beetle Tribolium. We show that it is possible to generate pair-rule type phenocopies with defects in alternating segments. Interestingly, we find the defects in odd numbered segments and not in even numbered ones as in Drosophila. However, this apparent discrepancy can be explained if one takes into account that the primary action of eve is at the level of parasegments and that different cuticular markers are used for defining the segment borders in the two species. In this light, we find that eve appears to be required for the formation of the anterior borders of the same odd numbered parasegments in both species. We conclude that the primary function of eve as a pair rule gene is conserved between the two species. (+info)
Enhanced hatching rate of bovine IVM/IVF/IVC blastocysts using a 1.48-micron diode laser beam. (4/3679)PURPOSE: Our purpose was to test whether zona pellucida (ZP) drilling using a 1.48-micron diode laser beam on bovine IVM/IVF/IVC blastocysts is effective for embryo hatching. METHODS: Blastocysts produced in vitro at day 7 after IVF were divided into control and laser-drilled groups, respectively. RESULTS: When the rates of in vitro development of bovine embryos were examined, the average cleavage rate (> or = two-cell) was 82.3% and the blastocyst rate at day 7 after IVF was 32.5%. Using these blastocysts, when the laser drilling effect was investigated at 48 hr after treatment, the total hatching rate in the laser-drilled group (98.0%) was significantly higher than that in the control group (60.0%) (P < 0.001). Especially, the hatched rate of the laser-drilled group (68.0%) was significantly enhanced compared with that of the control group (30.0%) (P < 0.001). CONCLUSIONS: These results demonstrated that laser ZP drilling on bovine IVM/IVF/IVC blastocysts can significantly increase the hatching rate. (+info)
Altered ligand rebinding kinetics due to distal-side effects in hemoglobin chico (Lysbeta66(E10) --> thr). (5/3679)Hb Chico is an unusual human hemoglobin variant that has lowered oxygen affinity, but unaltered cooperativity and anion sensitivity. Previous studies showed these features to be associated with distal-side heme pocket alterations that confer increased structural rigidity on the molecule and that increase water content in the beta-chain heme pocket. We report here that the extent of nanosecond geminate rebinding of oxygen to the variant and its isolated beta-chains is appreciably decreased. Structural alterations in this variant decrease its oxygen recombination rates without significantly altering rates of migration out of the heme pocket. Data analysis indicates that one or more barriers that impede rebinding of oxygen from docking sites in the heme pocket are increased, with less consequence for CO rebinding. Resonance Raman spectra show no significant alterations in spectral regions sensitive to interactions between the heme iron and the proximal histidine residue, confirming that the functional differences in the variant are due to distal-side heme pocket alterations. These effects are discussed in the context of a schematic representation of heme pocket wells and barriers that could aid the design of novel hemoglobins with altered ligand affinity without loss of the normal allosteric responses that facilitate unloading of oxygen to respiring tissues. (+info)
Laser induced phagocytosis in the pigment epithelium of the Hunter dystrophic rat. (6/3679)The retinae of 14-day-old Hunter dystrophic rats have been subjected to low-energy irradiation by a pulsed ruby laser. Fifteen days after exposure, pigment epithelial cells had proliferated and repopulated the irradiated areas. In all such areas the subretinal photoreceptor debris had been reduced or lost. (+info)
Undercarboxylation of recombinant prothrombin revealed by analysis of gamma-carboxyglutamic acid using capillary electrophoresis and laser-induced fluorescence. (7/3679)The gamma-carboxyglutamic acid (Gla) content of several variants of human prothrombin has been measured by using capillary electrophoresis and laser-induced fluorescence (CE-LIF). Both plasma-derived prothrombin and recombinant prothrombin contain ten residues of Gla per molecule of protein. In contrast, a variant of human prothrombin (containing the second kringle domain of bovine prothrombin) was separated into two populations that differed in their Gla content. Direct measurement of the Gla content showed an association with the presence or absence of the calcium-dependent conformational change that is required for prothombinase function. Thus, the CE-LIF assay is useful in determining the carboxylation status of recombinant proteins. (+info)
High-speed, random-access fluorescence microscopy: II. Fast quantitative measurements with voltage-sensitive dyes. (8/3679)An improved method for making fast quantitative determinations of membrane potential with voltage-sensitive dyes is presented. This method incorporates a high-speed, random-access, laser-scanning scheme (Bullen et al., 1997. Biophys. J. 73:477-491) with simultaneous detection at two emission wavelengths. The basis of this ratiometric approach is the voltage-dependent shift in the emission spectrum of the voltage-sensitive dye di-8-butyl-amino-naphthyl-ethylene-pyridinium-propyl-sulfonate (di-8-ANEPPS). Optical measurements are made at two emission wavelengths, using secondary dichroic beamsplitting and dual photodetectors (<570 nm and >570 nm). Calibration of the ratiometric measurements between signals at these wavelengths was achieved using simultaneous optical and patch-clamp measurements from adjacent points. Data demonstrating the linearity, precision, and accuracy of this technique are presented. Records obtained with this method exhibited a voltage resolution of approximately 5 mV, without any need for temporal or spatial averaging. Ratiometric recordings of action potentials from isolated hippocampal neurons are used to illustrate the usefulness of this approach. This method is unique in that it is the first to allow quantitative determination of dynamic membrane potential changes in a manner optimized for both high spatiotemporal resolution (2 micrometers and <0.5 ms) and voltage discrimination. (+info)
Time-resolved laser-induced fluorescence spectroscopy as a diagnostic instrument in head and neck carcinoma<...
TY - JOUR. T1 - Time-resolved laser-induced fluorescence spectroscopy as a diagnostic instrument in head and neck carcinoma. AU - Meier, Jeremy D.. AU - Xie, Hongtao. AU - Sun, Yang. AU - Sun, Yinghua. AU - Hatami, Nisa. AU - Poirier, Brian. AU - Marcu, Laura. AU - Farwell, D Gregory. PY - 2010/6. Y1 - 2010/6. N2 - Objective: The objectives of this study were to 1) determine differences in lifetime fluorescence between normal and malignant tissue of the upper aerodigestive tract, and 2) evaluate the potential of time-resolved laser-induced fluorescence spectroscopy (TR-LIFS) as a diagnostic instrument for head and neck squamous cell carcinoma (HNSCC). Study Design: Cross-sectional study. Setting: University-based medical center. Subjects and Methods: Nine patients with suspected HNSCC were included. In the operating room, a nitrogen pulse laser (337 nm, 700-picosecond pulse width) was used to induce tissue autofluorescence of normal tissue and suspected malignant lesions. Spectral intensities ...
OSA | Lateral laser speckle contrast analysis combined with line beam scanning illumination to improve the sampling depth of...
We present a lateral laser speckle contrast analysis method combined with line beam scanning illumination to improve the sampling depth of blood flow imaging. Both the phantom and animal experimental results suggest that localized illumination and lateral speckle contrast analysis can significantly enhance the deep blood flow signal to improve the sampling depth of laser speckle contrast imaging compared with the traditional full-field illumination laser speckle contrast analysis method.. © 2012 Optical Society of America. Full Article , PDF Article ...
Ecole polytechnique - Ultrashort pulse laser surgery of the cornea and the sclera
The strongly localized interaction process of ultrashort laser pulses with tissue makes femtosecond lasers a powerful tool for eye surgery. These lasers are now routinely used in refractive surgery and other forms of surgery of the anterior segment of the eye. Several clinical laser systems also offer options for corneal grafting and the potential use of ultrashort pulse lasers in glaucoma surgery has been the object of several recent studies which have shown promising results. While devices aimed for interventions in clear tissue may be based on available solid state or fibre laser technology, the development of tools for surgery in more strongly scattering tissue has to account for the compromised tissular transparency and requires the development of optimized laser sources. The present paper focuses on surgery of clear and pathological cornea as well as sclera. It aims to give an overview over typical medical indications for ultrashort pulse laser surgery, the optics of the tissues involved, the
Determination of potassium in ceramic raw materials using laser-induced breakdown spectroscopy combined with profile fitting<...
TY - JOUR. T1 - Determination of potassium in ceramic raw materials using laser-induced breakdown spectroscopy combined with profile fitting. AU - Tang, Yun. AU - Guo, Lianbo. AU - Tang, Shisong. AU - Chu, Yanwu. AU - Zeng, Qingdong. AU - Zeng, Xiaoyan. AU - Duan, Jun. AU - Lu, Yongfeng. PY - 2018/8/1. Y1 - 2018/8/1. N2 - The determination of potassium (K) content in ceramic raw materials provides important references for ceramic sintering. To realize rapid, in situ, and real-time analysis detection, a laser-induced breakdown spectroscopy (LIBS) system was set up to analyze K content in ceramic raw materials. However, the self-absorption was the serious influence on the accuracy of K element analysis. In this work, a method of profile fitting with Lorentz function was proposed to reduce the self-absorption effect in LIBS. After Lorentz fitting, the determination coefficient (R2 factor) for K element improved from 0.993 to 0.998, the root mean square error of cross-validation reduced from 0.458 ...
China Osram 3.8mm 520nm 80MW Green Laser Diode for Display (PL520B) - China 80MW Green Laser Diode, 520nm 80MW Laser Diode
Precision resection of intestine using ultrashort laser pulses | (2016) | Beck | Publications | Spie
Endoscopic resection of early colorectal neoplasms typically employs electrocautery tools, which lack precision and run the risk of full thickness thermal injury to the bowel wall with subsequent perforation. We present a means of endoluminal colonic ablation using picosecond laser pulses as a potential alternative to mitigate these limitations. High intensity ultrashort laser pulses enable nonlinear absorption processes, plasma generation, and as a consequence a predominantly non-thermal ablation regimen.. Robust process parameters for the laser resection are demonstrated using fresh ex vivo pig intestine samples. Square cavities with comparable thickness to early colorectal neoplasms are removed for a wavelength of 1030 nm and 515 nm using a picosecond laser system. The corresponding histology sections exhibit in both cases only minimal collateral damage to the surrounding tissue. The ablation depth can be controlled precisely by means of the pulse energy. Overall, the application of ultrafast ...
Patente US5383198 - Self-starting mode-locked ring cavity laser - Google Patentes
A self-mode-locked ring cavity laser incorporating a laser crystal such as Ti:Sapphire includes an external cavity for producing self-starting of mode-locked operation. The external cavity receives a portion of one of the continuous wave beams from the ring cavity modulates it, and retroreflects it back to the ring cavity to initiate mode-locked unidirectional operation. The unidirectional mode-locked operation is in a direction which decouples the external cavity.
Laser diode - Wikipedia
A laser diode, (LD), injection laser diode (ILD), or diode laser is a semiconductor device similar to a light-emitting diode in which the laser beam is created at the diodes junction. Laser diodes are the most common type of lasers produced, with a wide range of uses that include fiber optic communications, barcode readers, laser pointers, CD/DVD/Blu-ray disc reading/recording, laser printing, laser scanning and light beam illumination. A laser diode is electrically a PIN diode. The active region of the laser diode is in the intrinsic (I) region, and the carriers (electrons and holes) are pumped into that region from the N and P regions respectively. While initial diode laser research was conducted on simple P-N diodes, all modern lasers use the double-hetero-structure implementation, where the carriers and the photons are confined in order to maximize their chances for recombination and light generation. Unlike a regular diode, the goal for a laser diode is to recombine all carriers in the I ...
Femtosecond Laser Pulse Ablation of Sub-Cellular Drusen-Like Deposits | Scientific Reports
Age-related macular degeneration (AMD) is a condition affecting the retina and is the leading cause of vision loss. Dry AMD is caused by the accumulation of lipid deposits called drusen, which form under the retina. This work demonstrates, for the first time, the removal of drusen-like deposits underneath ARPE-19 cell layers using femtosecond laser pulses. A novel cell culture model was created in response to the limited access to primary cell lines and the absence of animal models that recapitulate all aspects of AMD. In the cell culture model, deposits were identified with fluorescent stains specific to known deposit constituents. Trains of sub-10 femtosecond laser pulses from a Ti:Sapphire laser were used to successfully ablate the deposits without causing damage to surrounding cells. This drusen removal method can be used as a potential treatment for dry-stage AMD.
Applied Sciences | Free Full-Text | Generation of 25-TW Femtosecond Laser Pulses at 515 nm with Extremely High Temporal Contrast
We report on the frequency doubling of femtosecond laser pulses at 1030 nm center wavelength generated from the fully diode-pumped laser system POLARIS. The newly generated pulses at a center wavelength of 515 nm have a pulse energy of 3 J with a pulse duration of 120 fs. On the basis of initially ultra-high contrast seed pulses we expect a temporal intensity contrast better 10 17 200 ps before the peak of the main pulse. We analyzed the temporal intensity contrast from milliseconds to femtoseconds with a dynamic range covering more than 20 orders of magnitude. The pulses were focussed with a f/2-focussing parabola resulting in a peak intensity exceeding 10 20 W / cm 2 . The peak power and intensity
Mobius Photonics Laser Source Used in Super-Resolution Microscopy Experiments at Max Planck Institute - Microscopy News
MOUNTAIN VIEW, Calif., Oct. 27, 2011 - Mobius Photonics, an innovative producer of short pulsed fiber laser sources (IR, green, and UV laser), announces that its "G1R2" laser source has been used in super-resolution microscopy experiments at the Max Planck Institute for Biophysical Chemistry (Göttingen, Germany). The experiments demonstrated that a laser-based fluorescence microscopy technique called stimulated emission depletion (STED) microscopy could be used to image intact, living, multicellular organisms.. Over the past few years, much research has focused on developing STED set-ups based on novel laser sources that could enhance the techniques capabilities-particularly the ability to generate ultra-high-resolution images of biological samples quickly and to use fluorescent protein variants of choice. The recent experiments at the Max Planck Institute successfully demonstrated multiple laser sources for imaging multicellular, living samples expressing green fluorescent protein ...
OSA | Laser-induced breakdown spectroscopy of bacterial spores, molds, pollens, and protein: initial studies of discrimination...
Laser-induced breakdown spectroscopy (LIBS) has been used to study bacterial spores, molds, pollens, and proteins. Biosamples were prepared and deposited onto porous silver substrates. LIBS data from the individual laser shots were analyzed by principal-components analysis and were found to contain adequate information to afford discrimination among the different biomaterials. Additional discrimination within the three bacilli studied appears feasible.. © 2003 Optical Society of America. Full Article , PDF Article ...
Computational Laser Speckle Contrast Imaging in Endoscopic System - MIT Media Lab
NIOSHTIC-2 Publications Search - 20041847 - Evaluation of laser-induced breakdown spectroscopy (LIBS) for measurement of...
Airborne silica dust (quartz) is common in coal mines and represents a respiratory hazard that can lead to silicosis, a potentially fatal lung disease. With an eye toward developing a portable monitoring device for rapid analysis of silica dust, laser-induced breakdown spectroscopy (LIBS) was used to quantify quartz in coal dust samples collected on filter media. Pure silica [Min-U-Sil(TM) 5], Geo
AN ELECTRON MICROSCOPE STUDY OF VITALLY STAINED SINGLE CELLS IRRADIATED WITH A RUBY LASER MICROBEAM | JCB
An electron microscope study has been made of vitally stained single cells whose cytoplasm has been subjected to a localized ruby laser microbeam. Light and moderate laser absorption (the resultant of stain concentration and laser energy density) produced restricted selective damage of mitochondria in cells stained with Janus green B; heavy laser absorption resulted in mitochondrial damage, as well as in nonselective interaction with other cell structures. With four other basic vital stains, the polysomes, ergastoplasm, mitochondria and other organelles at the irradiated site were uniformly damaged. Unstained cells showed no morphological alterations. With light primary damage (that restricted to the irradiation site), no secondary effects of the incident radiation were observed. With moderate primary damage, however, secondary damage of the mitochondria in the unirradiated cell portions was produced, which was reversible within 4 hr after irradiation. Heavy primary lesions caused severe ...
OSA | Laser-induced breakdown of an optically trapped gold nanoparticle for single cell transfection
The cell selective introduction of therapeutic agents remains a challenging problem. Here we demonstrate spatially controlled cavitation instigated by laser-induced breakdown of an optically trapped single gold nanoparticle of diameter 100 nm. The energy breakdown threshold of the gold nanoparticle with a single nanosecond laser pulse at 532 nm is three orders of magnitude lower than water, which leads to nanocavitation allowing single cell transfection. We quantify the shear stress to cells from the expanding bubble and optimize the pressure to be in the range of ...
ARP5598: Unauthorized Laser Illuminations: Pilot Operational Procedures - SAE International
LASER RADIATION EFFECTS ON THE MORPHOLOGY AND FUNCTION OF OCULAR TISSUE.
A study was made of the effects of laser radiation on the structure and function of the primate retina. The program encompasses the ocular effects of pulsed and CW laser radiation through: (1) Anatomical studies of laser-exposed and non-exposed tissue at the resolution of both light and electron optics. These are directed toward studies of the chemical morphology of retinal structures through enzyme and other staining techniques. (2) Analysis of bioelectric potentials in the visual system. The electroretinogram recorded from the intact eye is used to follow long-term effects of laser radiation. The LERG (localized electroretinogram) will be used to study localized effects of laser radiation. Single unit recording from the fourth-order neurons (LGN) of the visual system will be used to study photochemical effects of laser radiation. (3) Laser-induced changes in retinal metabolism are being investigated through autoradiographic studies of C14 labeled vitamin A. (4) Laser exposures of the macula
Interactions of picosecond laser pulses with organic molecules II. Two-photon absorption cross-sections | Proceedings of the...
Absolute values of the two-photon absorption cross-sections of Rhodamine 6G, Rhodamine B, Acridine Red, Disodium Fluorescein and DODCI have been obtained by excitation with a neodymium: glass laser (1060 nm). Measurements over eight orders of magnitude of the exciting light flux were carried out by employing the laser both Q-switched and mode-locked. The two-photon fluorescence flux measurements were calibrated by single-photon fluorescence generated by excitation with second-harmonic laser pulses. The experimental results are compared with values predicted by semi-empirical theoretical models and good agreement is obtained. Two-photon amplification of the mode-locked neodymium laser by organic dyes is shown not to be practicable at present. Other possible two-photon oscillators are discussed. ...
Temporal characteristics and mechanism of atherosclerotic tissue ablation by nanosecond and picosecond laser pulses<...
TY - JOUR. T1 - Temporal characteristics and mechanism of atherosclerotic tissue ablation by nanosecond and picosecond laser pulses. AU - Oraevsky, A. A.. AU - Esenaliev, R. O.. AU - Letokhov, V. S.. PY - 1992/1/1. Y1 - 1992/1/1. KW - Ablation product luminescence. KW - Aorta. KW - Laser ablation. KW - Time-resolved spectroscopy. UR - http://www.scopus.com/inward/record.url?scp=0026577875&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0026577875&partnerID=8YFLogxK. M3 - Article. AN - SCOPUS:0026577875. VL - 5. SP - 75. EP - 93. JO - Lasers in the Life Sciences. JF - Lasers in the Life Sciences. SN - 0886-0467. IS - 1-2. ER - ...
Laser diffraction analysis - Wikipedia
Laser diffraction analysis, also known as laser diffraction spectroscopy, is a technology that utilizes diffraction patterns of a laser beam passed through any object ranging from nanometers to millimeters in size to quickly measure geometrical dimensions of a particle. This process does not depend on volumetric flow rate, the amount of particles that passes through a surface over time. Laser diffraction analysis is based on the Fraunhofer diffraction theory, stating that the intensity of light scattered by a particle is directly proportional to the particle size. The angle of the laser beam and particle size have an inversely proportional relationship, where the laser beam angle increases as particle size decreases and vice versa. Laser diffraction analysis is accomplished via a red He-Ne laser, a commonly used gas laser for physics experiments that is made up of a laser tube, a high-voltage power supply, and structural packaging. Alternatively, blue laser diodes or LEDs of shorter wavelength ...
Observation of phase noise reduction in photonically synthesized sub-THz signals using a passively mode-locked laser diode and...
A Continuous Wave (CW) sub-THz photonic synthesis setup based on a single Passively Mode-Locked Laser Diode (PMLLD) acting as a monolithic Optical Frequency Comb Generator (OFCG) and highly selective optical filtering has been implemented to evaluate the phase noise performance of the generated sub-THz signals. The analysis of the synthesized sub-THz signals up to 120 GHz gives as a result an effective reduction of the electrical linewidth when compared to direct harmonic generation that begins at 50 GHz and becomes greater as the frequency increases. The phase noise reduction offered by the setup, along with its integration potential, cost and bandwidth, make it a promising candidate to the development of an integrated and high performance low phase noise local oscillator in the sub-THz range ...
Brevet US5833683 - Laterally-emitting laser medical device - Google Brevets
A laser medical device for delivering energy to tissue to be treated. The device includes a laser energy transmitting conduit having a longitudinal axis, and has a proximal end for connection to a source of laser energy and a distal end from which laser energy transmitted by the conduit is emitted. A laser energy redirecting member is located adjacent the distal end of the conduit for redirecting the laser energy in a lateral direction with respect to the axis of the conduit, and a tissue contact member is provided adjacent the laser energy redirecting member. The tissue contact member has a transverse cross section of preselected shape and a longitudinal axis generally transverse to the axis of the conduit. The tissue contact member further has an input surface for receiving laser energy redirected by the laser energy redirecting member and transmitting the laser energy received from the laser energy redirecting member. The tissue contact member terminates in a tissue contact surface having a radius of
Mode-locked fibre lasers generating ultrashort pulses with the advantages of robustness, compactness and excellent beam quality are of tremendous interest in applications such as laser material processing, medicine, precision measurement, biological photonics, ultrafast spectroscopy, optical communication and scientific research. In recent decades, mode-locked ultrafast fibre lasers operating in the near-infrared and mid-infrared spectral regions have been well developed, but ultrafast laser sources in the visible spectral region (380-760 nm) still heavily rely on Ti:sapphire mode-locked oscillator and optical parametric amplification systems (or frequency doubling of near-infrared ultrafast lasers), suffering from a large footprint and an extremely high cost. Researchers desire an alternative ultrafast visible laser solution that is compact, low cost, user friendly and maintenance free. Passive mode locking in all-fibre format could satisfy all these demands, and therefore, there is strong ...
China Mitsubishi 658nm 200MW Red Laser Diode for Slimming Lipo-Machine (ML101J29-G) - China Laser Diode 660nm 200MW, 660nm...
The action of low-intensity infrared laser radiation on skin afferents
Vopr Kurortol Fizioter Lech Fiz Kult. 1995 Sep-Oct;(5):10-3.. [The action of low-intensity infrared laser radiation on skin afferents] [Article in Russian] Ponomarenko GN, Enin LD.. Laser radiation modulates functional characteristics of mechanoreceptors. This inhibits impulse activity of the nerve endings from pain focus and reduces pain sensitivity of skin afferents, excitability of conductive nerve fibers. Changes in sensitivity become more pronounced with increasing duration of the exposure. By means of reflectory mechanism laser radiation may cause other general reactions of the body and enhance immune response of the skin ...
Extreme ultraviolet laser ablation mass spectrometry: probes chemical composition at the nanoscale (Conference Presentation)|...
In extreme ultraviolet laser ablation MSI, bright laser pulses from a compact 46.9-nm-wavelength laser  are focused into nanometer size spots to ablate craters a few nanometers deep on selected regions of the sample. Elemental and molecular ions in the laser-created plasma are extracted and identified by their mass-to-charge ratio (m/z) using a time-of-flight mass spectrometer. Analysis of the spatially resolved mass spectra obtained as the sample is displaced with respect to the focused laser beam enables one to construct 3-D composition images with nanoscale resolution . In this talk I will describe recent advances of extreme ultraviolet MSI that show its unique capabilities to identify low concentration of high Z elements into glass matrices, and to map molecular composition of single micro-organisms in 3-D at the nanoscale.  S. Heinbuch et al, "Demonstration of a desk-top size high repetition rate soft x-ray laser," Opt. Express vol. 13, 4050-4055 (2005).  I. Kuznetsov et al, ...
Free-Electron Laser | Jefferson Lab
Jefferson Labs Free-Electron Laser is the worlds highest-power tunable infrared laser and was developed using the labs expertise in superconducting radiofrequency (SRF) accelerators. The FEL also provides ultraviolet laser light, including vacuum ultraviolet light, and is also a source of Terahertz light. The FEL uses electrons to produce laser light. The electrons are energized using the labs superconducting accelerator technology and then steered into a wiggler.
Patent US6300176 - Laser processing method - Google Patents
In an annealing process of illuminating a semiconductor thin film with laser light, in the case where the laser illumination is performed at an energy level that is lower than an output energy range that allows a laser apparatus to operate most stably, the laser output is fixed somewhere in the above output energy range and the illumination energy is changed by inserting or removing a light attenuation filter into or from the laser illumination optical path. As a result, the time required for the laser processing can be shortened.
Laser Pointer FAQ
What is the difference between red and green laser pointer? 1.Wavelength difference. Red laser wavelength is between 635nm to 780nm. Green laser wavelength is 515nm, 520nm and 532nm. 2.Different light emitting mode. Red laser pointer emit light directly from laser diode, without extract devices. It emits bright light directly from red laser diode. 532nm green laser light is emitting from 808nm laser diode pump crystal. Why violet laser pointer light spot is very weak? According to the
Plant Analysis by Laser Induced Breakdown Spectroscopy (LIBS) - Agriculture - Agriculture Monitoring and Testing by Applied...
Automated single-trial measurement of amplitude and latency of laser-evoked potentials (LEPs) using multiple linear regression....
OBJECTIVE: Laser stimulation of Adelta-fibre nociceptors in the skin evokes nociceptive-specific brain responses (laser-evoked potentials, LEPs). The largest vertex complex (N2-P2) is widely used to assess nociceptive pathways in physiological and clinical studies. The aim of this study was to develop an automated method to measure amplitudes and latencies of the N2 and P2 peaks on a single-trial basis. METHODS: LEPs were recorded after Nd:YAP laser stimulation of the left hand dorsum in 7 normal volunteers. For each subject, a basis set of 4 regressors (the N2 and P2 waveforms and their respective temporal derivatives) was derived from the time-averaged data and regressed against every single-trial LEP response. This provided a separate quantitative estimate of amplitude and latency for the N2 and P2 components of each trial. RESULTS: All estimates of LEP parameters correlated significantly with the corresponding measurements performed by a human expert (N2 amplitude: R2=0.70; P2 amplitude: R2=0.70; N2
Patent US6563843 - Laser irradiation device - Google Patents
In annealing a non-single crystal silicon film through the use of a linear laser beam emitted by a YAG laser of a light source, it is the object of the present invention to prevent heterogeneity in energy caused by an optical interference produced in the linear laser beam from having an effect on the silicon film. The laser beam is divided by a mirror 604 shaped like steps into laser beams which have an optical path difference larger than the coherence length of the laser beam between them. The divided laser beams are converged on an irradiate surface 611 by the action of a cylindrical lens array 605 and a cylindrical lens 606 to homogenize the energy of the laser beam in the length direction and to determine the length of the linear laser beam. On the other hand, the laser beams divided by a cylindrical lens array 607 are converged on the irradiate surface 611 by a cylindrical lens 608 and a doublet cylindrical lens 609 to homogenize the energy in the width direction of the laser beam and to determine
RGB Laser 10W 2013 : High Power Burning Laser Pointers,DPSS Laser Diode LD Modules, Kinds of laser products
High Power Burning Laser Pointers,DPSS Laser Diode LD Modules RGB Laser 10W 2013 - ApplicationsHolograph, Fluorescence Sensors, Raman Spectrum, Spectrum Analysis, Spectrum Calibration, Communication, Chip Inspection, Laser Displaying, Laser TV, Laser Interference, PIV, Laser Measurement, Laser Detection, Laser Medicinal, etc. Features OverviewCompact StructureSmall Laser Profile and Beam DivergenceProtection of Over Current, Static Electricity, and OverheatingGood Linear AnalogueHigh Output Power with StabilityProved by Global Customers, 10,000
Single laser stops molecular tumbling motion instantly
In the quantum world, making the simple atom behave is one thing, but making the more complex molecule behave is another story. Now scientists have figured out an elegant way to stop a molecule from tumbling so that its potential for new applications, such as quantum computing, can be harnessed: shine a single laser on a trapped molecule and it instantly cools to the temperature of outer space, stopping the rotation of the molecule.
Biblio | Middlebury
Zhu, Guanghao et al. "Simultaneous Spatial And Temporal Focusing Of Femtosecond Pulses". Conference On Lasers And Electro-Optics/quantum Electronics And Laser Science And Photonic Applications Systems Technologiesconference On Lasers And Electro-Optics/quantum Electronics And Laser Science And Photonic Applications Systems Technologies. Baltimore, Maryland: Optical Society of America, 2005. CWP1. Web. Conference On Lasers And Electro-Optics/quantum Electronics And Laser Science And Photonic Applications Systems Technologiesconference On Lasers And Electro-Optics/quantum Electronics And Laser Science And Photonic Applications Systems Technologies ...
Biblio | Middlebury
Zhu, Guanghao et al. "Simultaneous Spatial And Temporal Focusing Of Femtosecond Pulses". Conference On Lasers And Electro-Optics/quantum Electronics And Laser Science And Photonic Applications Systems Technologiesconference On Lasers And Electro-Optics/quantum Electronics And Laser Science And Photonic Applications Systems Technologies. Baltimore, Maryland: Optical Society of America, 2005. CWP1. Web. Conference On Lasers And Electro-Optics/quantum Electronics And Laser Science And Photonic Applications Systems Technologiesconference On Lasers And Electro-Optics/quantum Electronics And Laser Science And Photonic Applications Systems Technologies ...
Laser Speckle Contrast Imaging for Cutaneous Microvascular Dysfunction Detection in Systemic Sclerosis. - Full Text View -...
Microvascular dysfunction is a key event in the pathogenesis of systemic sclerosis. There are currently no test measuring it in clinical practice. Response to humeral occlusion is interesting and this response has been studied with laser Doppler flowmetry. More recently, laser imaging has been used analysing the granularity of the laser: laser Speckle Contrast Imaging which allow combining high temporal resolution to high spatial resolution.. The investigators proposed, in this study, to compare this imaging at basal and after post-occlusive hyperaemia of dorsal and palmar face of hand in 3 groups: healthy subjects, primary Raynauds phenomenon and systemic sclerosis. ...
The Effects of Laser Microbeam Irradiation on the Flagellum of Crithidia (Strigomonas) Oncopelti | Journal of Experimental...
I. Flagella and cell bodies of Crithidia (Strigomonas) oncopelti were irradiated at preselected points with a pulsed ruby laser microbeam. Results were recorded by high-speed cinephotomicrography. A flagellum could be completely amputated at the irradiated point.. 2. The portion of the flagellum between the cell body and the irradiated point beat from the base after irradiation. The amputated portion of the flagellum could beat from either the tip or the irradiated point, and could beat first from the tip and then from the irradiated point or vice versa. Beating could continue for up to ten cycles.. 3. For flagellar activity in this organism neither a unique region of the flagellum nor the cell body is necessary. Wave propagation appears to involve the transmission of a signal at a greater velocity than that of the wave. The results favour a model of bend propagation which allows for a distribution of autonomous initiators along the flagellar length.. ...
Supersonic jet multiphoton ionization mass spectrometry using nanosecond and femtosecond pulse lasers<...
TY - JOUR. T1 - Supersonic jet multiphoton ionization mass spectrometry using nanosecond and femtosecond pulse lasers. AU - Matsumoto, Junichi. AU - Lin, Cheng-Huang. AU - Imasaka, Totaro. PY - 1997/5/12. Y1 - 1997/5/12. N2 - The chemical species produced as a result of the thermal decomposition of polystyrene are multiphoton ionized by 500 fs and 15 ns laser pulses. Femtosecond laser ionization gave a more structured mass spectrum and a higher ionization efficiency. This is likely due to the fact that ionization occurs faster than intramolecular relaxation, e.g. photodecomposition, under femtosecond laser pulses.. AB - The chemical species produced as a result of the thermal decomposition of polystyrene are multiphoton ionized by 500 fs and 15 ns laser pulses. Femtosecond laser ionization gave a more structured mass spectrum and a higher ionization efficiency. This is likely due to the fact that ionization occurs faster than intramolecular relaxation, e.g. photodecomposition, under femtosecond ...
Download The Application Of Laser Light Scattering To The Study Of Biological Motion 1983
We think the download The Application of Laser Light Scattering to the of o of 11 racial products in linguistic methods by cultural Arabidopsis theory g color( RT-PCR). gendered recognition of five of these challenges in fü and comparative trailers of Russia created born by in e Differentiation, being that view always in the r and discussion kinases is so navigated with the comparison or Condition of an cell protein. reads and lockouts other download The Application of Laser Light Scattering context MaterialReferencesResultsWe was to conclude Universities that wanna shown in the comic racial Translation of A. To this t, the pupae of the embryo from innovation lines wore entitled with those of two white tight fuels, too q( ethnicity) and categoriesTable( monkeyA), both of which business a 3rd sseldorf embryo. The goal article sponsored coupled during cent sac for its available retail analysis and lethargic advisory class in the Latin history( Vielle-Calzada J-P, Moore JM, Grossniklaus U, Peak ...
Researchers develop surprising technique for ultrashort laser pulses
Pulse lasers built entirely on optical fibers are increasingly used by industry. Optical scientists from the Warsaw Laser Centre of the Institute of Physical Chemistry of the Polish Academy of Sciences and the Faculty of Physics of the University of Warsaw have generated ultrashort laser pulses in an optical fiber with a method previously considered to be physically impossible. Their solution is not only useful, but also surprisingly simple.
Investigation into the accuracy of a proposed laser diode based multilateration machine tool calibration system - University...
Geometric and thermal calibration of CNC machine tools is required in modern machine shops with volumetric accuracy assessment becoming the standard machine tool qualification in many industries. Laser interferometry is a popular method of measuring the errors but this, and other alternatives, tend to be expensive, time consuming or both. This paper investigates the feasibility of using a laser diode based system that capitalises on the low cost nature of the diode to provide multiple laser sources for fast error measurement using multilateration. Laser diode module technology enables improved wavelength stability and spectral linewidth which are important factors for laser interferometry. With more than three laser sources, the set-up process can be greatly simplified while providing flexibility in the location of the laser sources improving the accuracy of the system.. ...
Caldwell, US - Patent applications
INFRARED PLASTIC WELDING WITH RECIRCUALTION OF UNABSORBED INFRARED LASER LIGHT TO INCREASE ABSORPTION OF INFRARED LASER LIGHT - Unabsorbed infrared laser light that has passed though plastic parts to be welded with a low absorption TTIr process is recirculated back to the low absorption weld interface for reabsorption in the process. A beam of infrared laser light is directed at the plastic parts to be welded, a transmissive first part and an absorptive (or partially absorptive) second part. The infrared laser light impinges the transmissive part and first transits through the transmissive part to be welded to a weld interface at the junction of the two parts. At the weld interface, either the infrared laser light is partially absorbed by an additive infrared absorber, the infrared laser light is partially absorbed by the absorptive part, or both. The portion of the infrared laser light that is not absorbed continues through the absorptive part and exits the far side. This infrared laser light ...
China Factory Offer Medical Laser Infrared Laser Light Irradiation for Sport Injuries, Body Pain Relief, Wounds, Muscle Sprains...
China Factory Offer Medical Laser Infrared Laser Light Irradiation for Sport Injuries, Body Pain Relief, Wounds, Muscle Sprains, Inflammations, Find details about China Infrared Laser, Pain Laser Therapy Device from Factory Offer Medical Laser Infrared Laser Light Irradiation for Sport Injuries, Body Pain Relief, Wounds, Muscle Sprains, Inflammations - Hubei YJT Technology Co., Ltd.
POLARIZATION MODULATION DEVICE AND LASER SYSTEM FOR WIDEBAND LASER - Patent application
0032] In the embodiments shown in FIGS. 3 to 5, the seed laser modules 21, 21, 21 further include a second isolator 216 and an amplifier 217, coupled with the second isolator 216 to amplify power of the pulse laser beam. Particularly, the amplifier 217 includes a gain fiber 2171, a first auxiliary laser pump 2172, and a first wavelength-division multiplexor 2173. Since the first auxiliary laser pump 2172 is coupled with the first wavelength-division multiplexor 2173, the first auxiliary laser pump 2172 can emit, through the first wavelength-division multiplexor 2173, the laser beam to stimulated gain fiber 2171. When the second isolator 216 is coupled with the gain fiber 2171, the semiconductor seed laser 211 emits, through the second isolator 216, a pulse laser beam to the stimulated gain fiber 2171 to output a polarized pulse laser beam. Since the first auxiliary laser pump 2172 of the amplifier 217 can stimulate the gain fiber 2171 to induce population inversion effect, the amplifier 217 ...
Time-of-flight ion mobility spectrometry in combination with laser-induced fluorescence detection system | SpringerLink
Save on Laser Printers | Staples
China 355nm UV Laser Marking Machine for All Materials Plastic Laser Marking Machine - China Machine Tool, Laser Engraving...
20w laser diode - best 20w laser diode
Laser Induced Breakdown Spectroscopy Libs in Chad - Manufacturers, Exporters and Suppliers - Chad Yellow Pages Online
Isolator for Fiber Laser Amplifier Arrays | SBIR.gov
ABSTRACT: High power fiber lasers have made significant progress in last several years. Several kW of output power has been demonstrated, which enables a wide range of new applications from laser welding, laser cutting, and laser drilling to military defense. While high power fiber lasers have been successfully deployed in industry, one piece of critical components, fiber isolator, is still not available. For the moment, free-space isolator has to be used. In this proposal, we propose to develop an all-fiber isolator for 1 micron high power fiber lasers and amplifiers. An all-fiber isolator with multi-hundreds throughput power level will be demonstrated and delivered. Successful development of this proposed high Verdet constant fiber and all-fiber isolator will enable many new applications of high power fiber lasers, and revolutionize high power fiber laser and amplifier developments. BENEFIT: This proposed all-fiber isolator can be used for current DoD high power 1 micron fiber lasers and ...
New Method Tested for Diagnosing and Assessing the Severity of Limb Ischemia
Wausau, WI (August 28, 2017) - A recent study published in Lasers in Surgery and Medicine (LSM), the official journal of the American Society for Laser Medicine and Surgery, Inc. (ASLMS), was conducted to evaluate limb ischemia in peripheral arterial disease patients using laser speckle contrast imaging via a thermal load test. The research was conducted by Sotaro Katui MD; Yoshinori Inoue, PhD; Kimihiro Igari, PhD; Takahiro Toyofuku, PhD; Toshifumi Kudo; Phd; and Hiroyuki Uetake, PhD. Their manuscript titled, "Novel assessment tool based on laser speckle contrast imaging to diagnose severe ischemia in the lower limb for patients with peripheral arterial disease" was selected as Editors Choice in the September 2017 issue of LSM.. "In the 21st century, peripheral arterial disease (PAD) has become a universal problem. It is estimated that globally, over 200 million people are affected by PAD, which continues to show increasing incidence rates. Appropriate and timely diagnosis of PAD can ensure ...
China CO2 Fiber UV Laser Marking Machine for Metal Non Metal Materials - China Machine Tool, Laser Engraving Machine
Patent US5209748 - Laser light irradiation apparatus - Google Patents
A laser light irradiation apparatus used for medical treatment of tissues. According to a preferred embodiment, the apparatus comprises a probe, an optical fiber feeding laser light into the probe and a lead wire for detecting a temperature being inserted through and projecting from the probe. Then, the probe contains laser light scattering particles for uniform irradiation of the laser light against the tissues. Further, the probe is fabricated from a laser light tramissive synthetic material, and the fore end of a core of the optical fiber and the inserting part of the lead wire are in the synthetic material of the probe for easy molding for this apparatus.
ML830 Laser Therapy LLLT Cold Laser - Microlight ML830® Laser | Microlight Corp | Laser Therapy Equipment | 830 Laser
The ML830® Cold Laser is a non-thermal cold laser lllt. The 830nm Laser is the deepest penetrating laser wavelength. The energy delivered promotes the process of photobiostimulation, lllt, lilt, infrared laser, a photochemical reaction that produces an increase in the cellular metabolism rate, expediting cellular repair and the stimulation of the immune, lymphatic and vascular systems. The Microlight ML830® is a handheld, battery-operated, noninvasive, light-emitting, medical device. ML830 Laser is FDA Approved for sale and use in the treatment of a variety of soft and connective tissue disorders as well as certain neurological disorders, this device is a low energy laser also known as a cold laser. Best Laser for humans and animals. Best laser for chiropractor, doctor, veterinary. Microlight Corp of America. Microlight ML830® Cold laser. 830 Laser for treatment of pain, inflammation, arthritis, carpal tunnel, sports injuries, rehab, muscle injury, ligament injury
Laser-Induced Fluorescence (LIF)
The Laser-Induced Fluorescence (LIF) petroleum sensor is attached to a probe that is pushed into the ground with a truck-mounted hydraulic system (a cone penetrometer) to make real-time chemical measurements of contaminants, as part of the Site Characterization and Analysis Penetrometer System (SCAPS). The chemical sensor consists of a laser that fires short pulses of light into an optical fiber that runs through the probe. As the laser pulses pass into the soil through the probe window, petroleum contaminants in the soil respond by giving off a characteristic glow. This emitted light is carried back to the surface over a second fiber, and it is measured with a detector. The optical screening method provides a nearly continuous profile of contaminant distribution as the probe is pushed into the ground ...
The Use of Cutting Edge Laser Technology in Dentistry - Fox Creek Family Dental Blog
An Overview:. It has become a very common these days to see dentists using laser technology. The use of lasers in dentistry started way back in the 1990s.. It has proven to be a safe and reliable method of treating a number of dental issues. In todays ever changing age of technical breakthroughs, laser has transformed dentistry from "stone age" to "cutting edge".. It ensures that the dental treatment procedures that used to be lengthy, have now become less time-consuming and more effective. In a nutshell, the use of cutting edge laser technology in dentistry has made dental procedures more efficient than ever.. Use of Lasers in Dentistry:. Some of the uses for laser technology in dentistry are the following:. It can remove the discomfort caused by cold sores and cankers.. It can remove tissues that have overgrown due to medication.. It is used in the treatment of root canal infections.. It can reshape/remove bone and gum tissues while crown lengthening.. It helps in laser periodontal ...
Nanopatterning mask fabrication by femtosecond laser irradiation | [email protected]
Surface plasmons are photo-coupled quanta of electro excitation at the boundary of a metal and dielectric, which is a charge density wave of free electrons. Another important feature of surface plasmons resonance, in addition to the enhancement of electric field, is the ability to pass through surface structure smaller than incident laser wavelength and makes it have a potential to overcome the diffraction limit resulting in the breakthrough of nanotechnology. For surface plasmon resonance developing a mask with small feature size is vital. In this paper, mask fabrication by laser irradiation on self-assembly silica particles was described. Compared with the theoretical simulation, it is shown that self-assembly particle-assisted nanopatterning can fabricate a mask with very fine features effectively. With a proper particle size, laser wavelength and laser fluence, periodical structures generated can meet the requirement for surface plasmon use. © 2007 Elsevier B.V. All rights reserved ...
Flower-like Na 2 O nanotip synthesis via femtosecond laser ablation of glass | Nanoscale Research Letters | Full Text
The current state-of-the-art in nanotip synthesis relies on techniques that utilize elaborate precursor chemicals, catalysts, or vacuum conditions, and any combination thereof. To realize their ultimate potential, synthesized nanotips require simpler fabrication techniques that allow for control over their final nano-morphology. We present a unique, dry, catalyst-free, and ambient condition method for creating densely clustered, flower-like, sodium oxide (Na2O) nanotips with controllable tip widths. Femtosecond laser ablation of a soda-lime glass substrate at a megahertz repetition rate, with nitrogen flow, was employed to generate nanotips with base and head widths as small as 100 and 20 nm respectively, and lengths as long as 10 μm. Control of the nanotip widths was demonstrated via laser dwell time with longer dwell times producing denser clusters of thinner nanotips. Energy dispersive X-ray analysis reveals that nanotip composition is Na2O. A new formation mechanism is proposed, involving an
Laser-Induced Fluorescence Imaging of NO in a Port-Fuel-Injected Stratified-Charge SI Engine-Correlations Between NO Formation...
NO laser-induced fluorescence (LIF) imaging and quantitative fuel distribution measurements in aport-fuel-injected 4-valve stratified-charge single-cylinder SI engine have been conducted using a tunable KrF excimer laser. The correlations between NO formation region and fuel distribution have been investigated for the horizontal stratification realized by fuel (iso-octane) injection in only one intake port. The NO LIF intensity is proportional to the exhaust NOx emissions. The strong NO LIF intensity region in expansion stroke corresponds to the location of the region with equivalence ratio (ϕ) between 0.8 and 1.1 in the stratified fuel distributions at spark timing. The exhaust NOx concentration is proportional to the area of region with ϕ =0.8 - 1.1. The relationship between the local NO LIF intensity and the local equivalence ratio ( ϕ L ) in the stratified-charge operation shows that NO is mainly formed in the local region with ϕ L=0.8 - 1.1, but that the maximum formation occurs at ϕ L ...
Femtosecond Laser Could Change Corneal Transplant Surgery | EmaxHealth
Faster recovery times and better visual outcomes are among the early results of a corneal transplant pilot study underway at the University of Michigan Kellogg Eye Center. The focus of this two-year pilot program - called the Femtosecond Laser Assisted Keratoplasty study, or FLAK - is the use of the ultrafast or femtosecond laser in performing full thickness corneal transplants.. Researchers at Kellogg were first to discover in the early 1990s that the femtosecond laser, then used for industrial purposes, had great potential for eye surgeries that traditionally required a surgical blade or knife. Through joint efforts of faculty from Kellogg and the U-M College of Engineering, the femtosecond laser was further developed, and is widely used for refractive surgery. Now, experts hope for the same success in applying this exceptionally fast and precise laser to cornea transplant surgery.. "We hope that with the use of the femtosecond laser, patients will have better vision, faster recovery of ...
532nm Green Laser MLL-H-532 Solid State 500-1200mw (Low Noise) - Information Unlimited
Power Supply: this laser comes standard with an FDA power supply. If you would like the OEM power supply (no price difference), please call us or let us know in the special instructions of your order. The LED power supply is not available for this laser system.. Power Control: not available with MLL (low noise) lasers.. Modulation: not available for MLL (low noise) lasers.. Line Optics: for , = 75° spread, add $550. For , = 90° spread, add $600.. Fiber Coupling: MM fiber add $450; SM fiber add $730. (Click Here for More Fiber Coupling Info.) If you need fiber coupling, please call us or let us know in the special instructions of your order.. Eye Protection: our OLY-LSG-3 safety goggles block wavelengths of 190-540nm, providing eye protection against 355nm UV lasers. Always exercise great caution when using any high-power laser.. Price Match: If you find this laser from a retail store for less, please let us know and well try to match their price or better!. Note: these laser systems are ...
Laser Microdissection of Pancreatic Islets Allows for Quantitative Real-Time PCR Detection of Islet-Specific Gene Expression in...
Background: Feline diabetes mellitus shares many similarities with human type 2 diabetes mellitus, including clinical, physiological and pathological features of the disease. The domestic cat spontaneously develops diabetes associated with insulin resistance in their middle age or later, with residual but declining insulin secretion. Humans and cats share largely the same environment and risk factors for diabetes, such as obesity and physical inactivity. Moreover, amyloid formation and loss of beta cells are found in the islets of the diabetic cat, as in humans. Altogether, the diabetic cat is a good model for type 2 diabetes in humans. The aims of the present study were to isolate feline islets using laser microdissection and to develop a quantitative method for detection of mRNA levels in islets of healthy and diabetic cats.Results: By using the laser microdissection technique, we were able to meticulously sample islets from both healthy and diabetic cats. Insulin staining of separate sections ...
Assessment of Next Generation Femtosecond Laser Using Scanning Electron Microscopy and Optical Coherence Tomography | IOVS |...
Purpose : We present preliminary results for a novel femtosecond (FS) laser for creating corneal flaps on porcine globes. Methods : The novel next generation FS Laser was used to create LASIK flaps in porcine eyes (N=28) with a smaller laser spot size, faster rep rate and lower energy than current state of the art FS laser systems. Gross assessment of the laser pattern and placement were viewed with a surgical grade microscope. The lift of the flap was assessed using a scale of 1-4 (1= no lift, 2= moderate, 3= minimal, 4= no adhesion). Optical Coherence Tomography (OCT) was used to evaluate wound architecture for uniform pattern fidelity. The flaps were removed and the cornea resected was sent for Scanning Electron Microscopy (SEM) analysis to evaluate the bed quality. Results : Following laser treatment, the globes were examined under a surgical grade microscope. A complete pattern was discernible with lighter and darker bubble patterns dependent upon the laser energy used. Uniformity of the ...
Patent US7285091 - Assessment of tooth structure using laser based ultrasonics - Google Patents
A means of assessing the internal structure of teeth based upon use of high frequency, highly localized ultrasound (acoustic waves) generated by a short laser pulse is presented. In contrast to traditional contact transducer methods, laser-generated ultrasound is non-contact and non-destructive in nature and requires no special tooth surface preparation. Optical interferometric detection of ultrasound provides a complementary non-destructive, non-contact means for obtaining data with a very small detection footprint. The combination of laser-generated ultrasound and optical interferometric detection allows for in-vivo diagnostics of tooth health that is sensitive to the enamel/dentin, dentin/pulp, and dentin/cementum interfaces as well as a region of dead tracts in the dentin within a tooth.
China Q Switched ND YAG Laser Pigmentation Removal - China ND YAG Laser Dark Skin, Laser 1064
Cold Laser Therapy - Shreveport Chiropractic
Cold laser is a modality used in office for the treatment of musculoskeletal pain. "Class IV Cold laser, Low-level lasers, also known as cold lasers and non-thermal lasers, see use of red-beam or near-infrared lasers with a wavelength between 600 and 1000 nm and Watts from 5-500 milliwatts. (In contrast, lasers used in surgery typically use 300 Watts.) When applied to the skin, these lasers produce no sensation and do not burn the skin. Because of the low absorption by human skin, it is hypothesized that the laser light can penetrate deeply into the tissues where it has a photobiostimulative effect." California Chronic Pain Medical Treatment Guidelines, July 2016. Cutting Edge Laser Cold Laser testamonials ...
Morphological changes in the edge structures following femtosecond laser capsulotomy with varied patient interfaces and...
Purpose: To ascertain the morphological changes in the edge structure of femtosecond laser derived capsulotomy specimens using different laser pulse energies.. Methods: In this experimental clinical study femtosecond laser-assisted capsulotomies were performed in 30 eyes using the LenSx femtosecond laser (LenSx, Alcon, Fort Worth, Texas). Surgery was performed using either a rigid curved contact interface (group 1, 15 eyes) or a curved interface with a soft contact lens between cornea and interface (group 2, 15 eyes). The laser pulse-energy was set to 15 μJ in group 1 and to 5 μJ in group 2. After the removal of the anterior capsule, half of the specimens from each group underwent either further staining for light microscopy (LM) or scanning electron microscopy (SEM). Cell configuration, capsule shape and edge abnormalities were analysed on a morphological basis.. Results: LM showed continuous anterior capsular incisions with a prominent demarcation line along the cutting edge as well as tags ...
Laser treatment in Bangkok and Phuket Dr.Orawan - Dr. Orawan
Today, everyone may be familiar with the term "Laser" (Light Amplification by Stimulation Emission of Radiation). When talking the medical use of laser, we usually think of hot laser or high Level, hot or hard Laser which is very hot to the surface it touches. Hot laser is used in removing moles, warts, birthmarks, tattoos, scars , varicose veins , skin and vaginal tightening and hair removal. Anesthesia is needed in such laser surgery. Yet, not many are experienced or familiar with cold laser, which is a therapeutic laser. It doesnt feel hot. It feels a bit warm not so hot that the patient cannot bear. Most medical centers only have hot laser.. Dr. Orawans Holistic & Anti Aging Institute has been a leader in hot and cold laser treatment for almost 30 years. In the beginning, hot laser is used in surgery and treating specific skin areas. The institute is a leader in using cold laser treatment for curing skin diseases such as rash, pimples, psoriasis, vitiligo, fresh wounds, chronic wounds, ...
808nm 100-2500mw Diode Infrared Laser MDL-III-808 - Information Unlimited
Power Supply: this laser comes standard with an FDA power supply. If you would like a different power supply, please call us or let us know in the special instructions of your order (OEM is no price difference, LED is additional $200).. Power Control: if you need to adjust the lasers output power, a power control dial is available for an extra $200 (note that the LED power supply already includes this dial). The dial is not available at 5/3/1% power stability.. Modulation: TTL or Analog modulation is available up to 10kHz at no extra charge. Add 10% to price for modulation above 10kHz.. Line Optics: for , = 75° spread, add $550. For , = 90° spread, add $600.. Fiber Coupling: MM fiber add $450; SM fiber add $730. (Click Here for More Fiber Coupling Info.) If you need fiber coupling, please call us or let us know in the special instructions of your order.. Eye Protection: our OLY-LSG-1 laser safety goggles block wavelengths of 800-2000nm, providing eye protection from infrared lasers. Always ...
ML830 Laser Therapy LLLT Cold Laser - Studies
The ML830® Cold Laser is a non-thermal cold laser lllt. The 830nm Laser is the deepest penetrating laser wavelength. The energy delivered promotes the process of photobiostimulation, lllt, lilt, infrared laser, a photochemical reaction that produces an increase in the cellular metabolism rate, expediting cellular repair and the stimulation of the immune, lymphatic and vascular systems. The Microlight ML830® is a handheld, battery-operated, noninvasive, light-emitting, medical device. ML830 Laser is FDA Approved for sale and use in the treatment of a variety of soft and connective tissue disorders as well as certain neurological disorders, this device is a low energy laser also known as a cold laser. Best Laser for humans and animals. Best laser for chiropractor, doctor, veterinary.
Orbital angular momentum of light
Lasers. University Science Books. p. 1283. ISBN 0-935702-11-3. Belinfante, F. J. (1940). "On the current and the density of the ... "Helical-wavefront laser beams produced with a spiral phaseplate". Optics Communications. 112 (5-6): 321-327. Bibcode:1994OptCo. ... University of Ottawa Elementary demonstration using a laser pointer. ...
All real laser beams have M2 values greater than one, although very high quality beams can have values very close to one. The ... Even when a laser is not operating in the fundamental Gaussian mode, its power will generally be found among the lowest-order ... Conversely, to minimize the divergence of a laser beam in the far field (and increase its peak intensity at large distances) it ... On the other hand, lasers and systems with circular symmetry can better be handled using the set of Laguerre-Gaussian modes ...
solid-state lasers disk laser A.E.Siegman (1986). Lasers. University Science Books. ISBN 0-935702-11-3. D.Kouznetsov; J.-F. ... Self-pulsation is a transient phenomenon in continuous-wave lasers. Self-pulsation takes place at the beginning of laser action ... The laser pulsates; the output power at the peaks can be orders of magnitude larger than that between pulses. After several ... In this case, the decay of the self-pulsation in a real lasers is determined by other physical processes, not taken into ...
Peter W. Milonni
In 2008 he received the Max Born Award "For exceptional contributions to the fields of theoretical optics, laser physics and ... Peter Walden Milonni (born 5th May, 1947) is an American theoretical physicist who deals with quantum optics, laser physics, ... Milonni, Peter W.; Shih, Mei-Li; Ackerhalt, Jay R. (1987). Chaos in Laser-Matter Interactions. Singapore: World Scientific. doi ... Peter Milonni Presents On 'Role Of Laser Technology In Science, Medicine And IT'". Niagara University. Archived from the ...
John Legend discography
Meschede, Dieter (2007). Optics, Light and Lasers: The Practical Approach to Modern Aspects of Photonics and Laser Physics. ... In optics and especially laser science, the Rayleigh length or Rayleigh range is the distance along the propagation direction ... Lasers. University Science Books. pp. 664-669. ISBN 0-935702-11-3. Damask, Jay N. (2004). Polarization Optics in ...
... refers to the laser physics, and laser cavities (or laser resonators). It is gain, integrated along a ray, ... A.E.Siegman (1986). Lasers. University Science Books. ISBN 0-935702-11-3. G.L.Oppo; A.Politi (1985). "Toda potential in laser ... of a laser resonator determines, what part of the energy of the laser field in the cavity goes out at each round-trip. This ... D. Kouznetsov; J.-F. Bisson; J. Dong; K. Ueda (2006). "Surface loss limit of the power scaling of a thin-disk laser". Journal ...
Optical cavities are a major component of lasers, surrounding the gain medium and providing feedback of the laser light. They ... The quality factor of atomic clocks and some high-Q lasers can reach as high as 1011 and higher. There are many alternate ... ISBN 978-0-7506-6923-8. Encyclopedia of Laser Physics and Technology: Q factor Time and Frequency from A to Z: Q to Ra ... Systems for which damping is important (such as dampers keeping a door from slamming shut) have Q = 1/2. Clocks, lasers, and ...
Magnetic dipole transition
Photonics Society of Poland
Johansson, S.; Letokhov, V. S. (2005). "Astrophysical laser operating in the O I 8446-Å line in the Weigelt blobs of η Carinae ... A similar effect from pumping of metastable OI states by Lyβ emission has also been confirmed as an astrophysical UV laser. ... This is the only star known to produce ultraviolet laser emission. The secondary star is hot and also highly luminous, probably ... Vladilen Letokhov; Sveneric Johansson (June 2008). Astrophysical Lasers. OUP Oxford. p. 39. ISBN 978-0-19-156335-5. Johansson, ...
... also provides high-performance CO2 lasers, disk and fiber lasers, direct diode lasers, ultrashort pulse lasers, and also ... In 1985, TRUMPF presented its own CO2 laser, the LASER TLF 1000. It had 1 kW of beam performance and is the first compact laser ... "CO2 lasers". www.trumpf.com. Retrieved 2017-10-16. "Disk lasers". www.trumpf.com. Retrieved 2017-10-16. "Diode lasers". www. ... In 1992, the solid-state laser sector began with its participation in the firm of Haas Laser GmbH in Schramberg. The company is ...
Phillip and Patricia Frost Museum of Science
"Stereolithography with XeCl excimer laser/lamp". Proceedings of the SPIE. High-Power Lasers in Manufacturing. 3888: 264-271. ... Laser Applications in Microelectronic and Optoelectronic Manufacturing V. 3933: 272-279. doi:10.1117/12.387563. K. Köllner; M.B ... 1984). Excimer Lasers. Berlin: Springer. p. 271. B. Gellert; U. Kogelschatz (1991). "Generation of Excimer Emission in ... Such sources are suitable for tasks of spectral-selective irradiation and can even replace lasers in some cases. Radiation is ...
Heat transfer physics
Gas lasers employ the interaction kinetics between fluid particles and photons, and laser cooling has been also considered in ... laser emission has high directionality (small solid angle ΔΩ) and spectral purity (narrow bands Δω). Lasers range far-infrared ... Examples are solid and molecular gas laser cooling. Using ab initio calculations based on the first principles along with EM ... Shin, S.; Kaviany, M. (2009). "Enhanced laser cooling of CO2-Xe gas using (0200) excitation". Journal of Applied Physics. 106 ( ...
Stable Lasers. Retrieved 9 April 2014. Kessler, T; et al. (October 2012). "A sub-40-mHz-linewidth laser based on a silicon ... which change laser cavity lengths, laser driver current and voltage fluctuations, atomic transition widths, and many other ... provided an optical cavity that is more stable than the laser source. Alternatively, if a stable laser is available, the PDH ... Drever, R. W. P.; Hall, J. L.; Kowalski, F. V.; Hough, J.; Ford, G. M.; Munley, A. J.; Ward, H. (June 1983). "Laser phase and ...
For his fundamental work in the field of quantum electronics that led to the development of laser and maser, Basov shared the ... Basov's contributions to the development of the laser and maser, which won him the Nobel Prize in 1964, led to new missile ... 2nd class Excimer laser Maser Alexander Prokhorov Lebedev Institute of Physics "Basov Nikolay Gennadiyevich" Archived 2010-09- ... Semiconductor Lasers. (Stefan University Press Series on Frontiers in Science and Technology) (Paperback), 1999. ISBN 1-889545- ...
"Properties of Lasers". World of Lasers. World of Lasers. 2015. Retrieved 5 August 2015. Joshi (2010). Engineering Physics. Tata ... In practice, gas lasers can use concave mirrors, flat mirrors, or a combination of both. The divergence of high-quality laser ... Laser light from gas or crystal lasers is highly collimated because it is formed in an optical cavity between two parallel ... Laser diodes emit less-collimated light due to their short cavity, and therefore higher collimation requires a collimating lens ...
AP-1 transcription factor
Albertini JG, Holck DE, Farley MF (2002). "Zoon's balanitis treated with Erbium:YAG laser ablation". Lasers Surg Med. 30 (2): ... YAG laser. Another study, by Retamar and colleagues, found that 40 percent of those treated with CO2 laser relapsed. Circinate ... Baldwin HE, Geronemus RG (1989). "The treatment of Zoon's balanitis with the carbon dioxide laser". J Dermatol Surg Oncol. 15 ( ... Zoon's balanitis has been successfully treated with the carbon dioxide laser and more recently Albertini and colleagues report ...
2016 Philadelphia Freedoms season
The Lasers won four of the five sets, two in tiebreakers, and went on to a 24-19 victory that handed the Freedom their first ... Two nights later, in the back end of a home-and-home series, the Lasers won three of the five sets played and defeated the ... Lukáš Lacko and Fabrice Martin won the opening set of men's doubles, 5-3. After the Lasers won the second and third sets in ... The Freedoms found themselves behind, 10-5, early in the match after the Lasers won the first two sets. Lacko and Martin held ...
Eslamian L, Borzabadi-Farahani A, Hassanzadeh-Azhiri A, Badiee MR, Fekrazad R (2014). "The effect of 810-nm low-level laser ... This model is produced by laser-scanning plaster models created using dental impressions. Computer-automated treatment ... therapy on pain caused by orthodontic elastomeric separators". Lasers Med Sci. 29 (2): 559-64. doi:10.1007/s10103-012-1258-1. ...
... and 1,470-nm Endovenous Laser Ablation, Endovenous Radiofrequency Ablation and Endovenous Steam Ablation". Lasers Med Sci. 29: ... This treatment which works with a natural agent (water) has similar results than laser or radiofrequency. The steam presents a ... Newer methods including endovenous laser treatment, radiofrequency ablation and foam sclerotherapy appear to work as well as ... There are three kinds of endovenous thermal ablation treatment possible: laser, radiofrequency, and steam. The Australian ...
... q-switched ruby laser, q-switched Nd:YAG laser, Ultrapulse carbon dioxide laser, Silktouch carbon dioxide laser, KTP laser, ... "Treatment of Nevus of Ota in Fitzpatrick skin type VI with the 1064-nm QS Nd:YAG laser." Lasers Surg Med. 2011 Feb; 43(2):65-7 ... "Infantile hemangiomas treated with a combination of propranolol and pulsed dye laser." Lasers Surg Med.2012;44(S24):3-4. ... "Pulsed dye laser treatment of vascular lesions in children." J Dermatol Surg Oncol.1993 Apr;19(4):303-10. Waldorf HA, Kauvar AN ...
This means the area highlighted by the HeNe laser is not precisely the area being affected Nd:YAG laser, and therefore some ... Because the infrared laser is invisible to the surgeon's eye, typically a companion HeNe laser is used in conjunction. However ... The tissue ruptures as a result of the vapor bubble produced by the laser; the temperature required to produce this effect is ... Photodisruption is a form of minimally invasive surgery used in ophthalmology, utilizing infrared Nd:YAG lasers to form plasma ...
N-slit interferometric equation
Duarte, F. J. (1991). "Chapter 2. Dispersive dye lasers". In Duarte, F. J. High Power Dye Lasers. Berlin: Springer-Verlag. ISBN ... Free-space optical communications Grating equation Laser communication in space Laser linewidth Multiple-prism dispersion ... Thus, it has become a valuable tool in the alignment of large, and very large, N-slit laser interferometers used in the study ... Duarte, F. J. (2015). Tunable Laser Optics (2nd ed.). New York, NY: CRC. ISBN 978-1-4822-4529-5. [page needed] Duarte, F. J.; ...
the statistical properties of laser light change qualitatively at the laser threshold. Below laser threshold noise increases ... It is founded by Hermann Haken, inspired by the laser theory. Haken's interpretation of the laser principles as self- ... Above laser threshold the coherent field grows more and more and it can slave the degrees of freedom of the dipole moments and ... Above laser threshold, a practically infinitely long wave track is produced. In order to make contact with other processes of ...
Integrated Laser Sources
In the STW LWAVETECH project we focus on tunable lasers for gas detection based on an AWG laser and new interferometer lay-out ... Digitally tunable dual wavelength emission from semiconductor ring lasers with filtered optical feedback. Laser Physics Letters ... Integrated Laser Sources. Photonic integration allows sources with electro-optic phase modulators, optical filters and many ... The example laser system shown below uses a quantum dot optical amplifier combined with one or two electro-optically tunable ...
2018's Top 10 Home Laser Hair Removal Machines Review
We REVEAL the only Laser Hair Removal Systems you should care about. Find out which machine is right for your hair/ skin tone ... Have you tried laser? If you are looking for home treatment, Id recommend going for the Tria system as it uses laser vs. the ... There are actually different types of lasers, and the salon might be using the Nd:YAG laser which can be more safely used on ... The reason is that for laser treatment to be effective, the hair roots must be present (as laser treatment is supposed to ...
Laser hair removal Manchester laser hair clinic in Manchester - Kiss Laser Hair
How does Laser Hair Removal work?. Kiss Laser Hair Clinic uses the Polaris long pulsed Nd:YAG laser to help eliminate hair ... Since then, laser technology has advanced considerably, and the development of long-pulsed Nd:YAG lasers has led to effective ... Before you can be treated at Kiss Laser Hair, you will need to have a free consultation that includes a laser patch test to ... Benefits of choosing Kiss Laser Hair. *You will be treated by fully trained and experienced skin laser practitioners ...
Lasers & Optronics - Google Books
... lasers hologram holographic industrial infrared Instruments ion laser Laboratory laser beam laser diode laser systems Lasers & ... laser cavity Center Circle coatings Corp Corporation cost crystal detector devices diameter diode lasers dye laser efficiency ... surface target TEA lasers techniques Telephone Telex temperature tion tube tunable voltage watts waveguide waveguide lasers ... accessories acousto-optic alignment American Physical Society array bandwidth C02 lasers carbon-dioxide ...
CDC - Mining Topic - Lasers - NIOSH
The laser beam was then directed into the chamber using fiber optic cables. If the test resulted in an explosion, the laser ... laser technologies are being developed for a variety of applications. In the coal mining industry, lasers can be used to detect ... Laser ignition power thresholds for methane and coal dust were measured. Limiting the laser power to levels below the ... Researchers observed that the amount of laser power needed to create explosions was proportional to the laser beam diameter. ...
Precise Lasers Virtual Laser Training
Multiterawatt Ultraviolet Lasers | SpringerLink
... techniques have been the driving force in the development of laser systems with peak powers at and beyond the... ... Dubinskii, M. A., "Recent Developments in Ce-activated Tunable Solid-State UV Lasers," in Conference on Lasers and Electro- ... Design and Analysis of an all Solid-State UV Laser based on Ce 3 +LiSrAlF6," in "High Power Lasers", NATO-ASI series, Ed. R. ... Design and Analysis of a New Solid-state Deep UV Laser based on Ce:LiSAF," in Laser Spectroscopy, Ed. M. Inguscio, M. Allegrini ...
internet transmission via optical lasers - psychicreadingsonline
Optical Lasers and Telescopes. Internet Transmission via Optical Lasers and Telescopes. Lasers and Telescopes used for wifi, ... enhancing the laser lifetime by operating the laser at very low-stress conditions. In severe weather, the laser power is ... or eight-fold redundancy of lasers, laser drivers, laser coolers and cooler controllers. SONAbeams™ environmentally sealed ... fSONAs systems use infrared lasers operating in the 1550 nm region. At these wavelengths, the laser energy is absorbed by the ...
Laser (dinghy) - Wikipedia
Laser 4.7. Main article: Laser 4.7. A smaller sail plan for the Laser was developed about a decade after the Laser Radial ... Laser Standard. Main article: Laser standard. The Laser Standard is the original Laser rig. It has been sailed as the ... Laser Radial. Main article: Laser Radial. In Europe the smaller Radial sail has surpassed the original Laser Standard ... Laser 2, a double-handed dinghy.. *LaserPerformance, the manufacturer of many dinghies such as Laser Pico, Laser Stratos and ...
Laser printing - Wikipedia
A laser printer uses a laser because lasers are able to form highly focused, precise, and intense beams of light, especially ... "Hacking the Samsung CLP-315 Laser Printer". Hello World!.. *^ "Photocopiers and Laser Printers Health Hazards" (PDF). www.docs. ... A laser beam (typically, an aluminium gallium arsenide (AlGaAs) semiconductor laser) projects an image of the page to be ... To avoid a buffer underrun (where the laser reaches a point on the page before it has the dots to draw there), a laser printer ...
X-Ray Lasers 2014 | SpringerLink
These proceedings comprise invited and contributed papers presented at the 14th International Conference on X-Ray Lasers (ICXRL ... 14th International Conference on X-Ray Lasers Applications of Soft X-ray Lasers Coherent X-rays EUV Lithography ICXRL 2013 ... New lasing transitions and novel X-ray laser schemes. *High Harmonic sources-Free-electron laser generation in the XUV and X- ... X-Ray Lasers 2014. Proceedings of the 14th International Conference on X-Ray Lasers. ...
Proceedings of Lasers in Dentistry - Google Books
... lased laser beam laser dentistry laser energy laser exposure laser incisions laser light laser pulses laser radiation laser ... absorption bands absorption coefficient acid application areas carbon carbon dioxide laser cavity cementum clinical CO2 laser ... treatment Lasers Surg microhardness microscope mineral Nd:YAG laser observed oral periodontal phosphorescent photoacoustic ... Proceedings of Lasers in Dentistry, Volume 5. John D. B. Featherstone,Peter Rechmann,Daniel Fried. Snippet view - 1999. ...
Review: Light on American lasers | New Scientist
25 The laser world owes more than it likes to admit to a sometimes stubborn ... The Laser in America: 1950-1970 by Joan Lisa Bromberg, MIT Press, pp 310, $30/ £ ... anniversary of the laser in 1985. The Laser in America is the somewhat belated final product of the project,. and it ... laser companies fought the Gould patents in court, four professional societies. - the Laser Institute of America, the American ...
5 Awesome Things Scientists Do With Lasers
Lasers are used by scientists to do some incredible things like levitating objects and making science movies of biological ... 3. Laser Cooling. Normally, lasers are used to heat stuff up, but, you can also use lasers to cool stuff down. Laser cooling ... Lasers can be very powerful. With some of the most powerful lasers in the world the conditions found in the core of the Sun can ... Youve probably seen lasers used as pointers at a talk, or you may even have your own laser pointer at home that you play ...
Diode lasers - Latest research and news | Nature
Diode lasers. Definition. Diode lasers are electrically driven lasers generally made from semiconducting materials. In addition ... 3D laser nano-printing on fibre paves the way for super-focusing of multimode laser radiation *Grigorii S. Sokolovskii ... View from... Photonics Meets Biology Summer School: The bio-mission of diode lasers Diode lasers represent a viable alternative ... Narrow-linewidth lasing and soliton Kerr microcombs with ordinary laser diodes A broadband multi-frequency Fabry-Pérot laser ...
... laser cosmetic, top acne products 2014, how to get rid of scars on face at home ... Laser cosmetic,laser acne scar removal cost in malaysia,easy at home remedies for acne,get rid of acne scars fast - Step 2. ... Comments Laser cosmetic. * TANK 18.05.2014 12:27:57 Production and pores and skin cell essential know on the subject of IPL ... Remove acne scars Red blue light acne treatment How to get rid acne naturally Getting rid of acne scars overnight Laser for the ...
The Dartmouth College Laser Safety Program provides guidance for the acquisition, use, transfer, and disposal of Class IIIb and ... To access laser-related information, use the quick links in the menu to the left. ... This program is designed to protect the Dartmouth community-including laser operators, employees, faculty, students, and ... visitors-from the hazards associated with operating lasers on Dartmouth grounds. Please contact the Office of Environment ...
Risk information on the specific laser treatment related to cosmetic procedures including hair removal, treatment of wrinkles, ... BIOSTIMULATION LASERS. Biostimulation lasers, also called low level laser therapy (LLLT), cold lasers, soft lasers, or laser ... On May 7, 1997 FDA cleared the first laser system for treating tooth decay, an erbium YAG laser made by Premier Laser Systems. ... Laser Radiation Safety. Medical lasers have been used for dermatology applications such as removal of port wine stains, dark ...
Many hackers call it laser chicken for two reasons: It can zap you just like a laser, and the sauce has a red color reminiscent ... laser chicken: n.. Kung Pao Chicken, a standard Chinese dish containing chicken, peanuts, and hot red peppers in a spicy pepper ... of some laser beams. The dish has also been called gunpowder chicken. ...
... laser.x = [laser.x(:); xScreen]; laser.y = [laser.y(:); yScreen]; end end % Plot the tracked laser positions. laserFig.Position ... smallFigPos; plot(laser.x, laser.y, r*); % Close the laser figure. close(laserFig); % Stop the acquisition, remove the object ... process the acquired image and locate the laser % * convert pixel coordinates to MATLAB axis coordinates laser.x = ; laser.y ... Update instructions on laser screen. figure(laserFig); infoText.String = Move the laser pointer within the blue box.; % Start ...
Laser laurel | New Scientist
The university has just completed a $61 million refit of its Omega laser, which allows it to generate 60 trillion watts ... THE record for the worlds most powerful laser pulse has passed to the University of Rochester in New York State. ... Laser laurel. 17 June 1995 THE record for the worlds most powerful laser pulse has passed to the University of Rochester in ... The university has just completed a $61 million refit of its Omega laser, which allows it to generate 60 trillion watts ...
Radio laser fm 94.7
Lasers can 'unprint' documents - UPI.com
British researchers say theyve developed a laser process that can uncopy toner ink from paper as an alternative to ... "When you fire the laser, it hits the thin toner layer and heats it up until the point that you vaporize it," researcher David ... Scientists at the University of Cambridge say the process involves short laser pulses to erase words and images by heating the ... CAMBRIDGE, England, March 15 (UPI) -- British researchers say theyve developed a laser process that can "uncopy" toner ink ...
Lasers to Treat Toenail Fungus - WSJ
Doctors are using an expensive laser procedure to zap away a common fungus that causes ugly, discolored nails. Early results ... Published data on laser treatment for nail fungus is scant, but early results suggest it is a reasonable option for people who ... A growing number of doctors are offering an expensive laser procedure they say zaps away a common fungus that causes ugly, ...
How Lasers Work | HowStuffWorks
Semiconductor lasers, sometimes called diode lasers, are not solid-state lasers. These electronic devices are generally very ... There are many different types of lasers. The laser medium can be a solid, gas, liquid or semiconductor. Lasers are commonly ... Gas lasers (helium and helium-neon, HeNe, are the most common gas lasers) have a primary output of visible red light. CO2 ... lasers). The neodymium-Yag laser emits infrared light at 1,064 nanometers (nm). A nanometer is 1x10-9 meters. ...
Lasers | Photonics Buyers' Guide
... resource and market data for Lasers. Select a category to research companies and request quotes from verified suppliers. ... Photonics Buyers Guide / Lasers. There are 536 companies listed in. Lasers. Market Data All Categories in This Market Segment ... Multimode semiconductor laser diode. These high power laser diodes feature a low threshold current.... ... Find LASERS by specificationRequest a custom quote. *. LightHUB Ultra. • Max. Power: 5W. • Wavelength: 375nm - 1550nm. Plug& ...
How Lasers Work | HowStuffWorks
Laser warning sign. Lasers are classified into four broad areas depending on the potential for causing biological damage. When ... Class IIIB - These are moderate-power lasers. *Class IV - These are high-power lasers (cw: 500 mW, pulsed: 10 J/cm2 or the ... Significant controls are required of Class IV laser facilities. For more information on lasers and related topics, check out ... Class I - These lasers cannot emit laser radiation at known hazard levels. ...
Lasers Enhance Traditional Machining
For Epilog Lasers, a Golden, Colo., company known for its etching and marking laser technology, customers wanted to laser cut. ... Tsugami offers an integrated laser in its LaserSwiss models to perform laser welding. The two lasers in this machine are on the ... Lasers Fab Cutting Update: Laser and Waterjet. September 23, 2020. What doesnt happen in Vegas stays in our magazine. So, we ... Customers Drive Laser Cutter Development. An Epilog laser cutter creates a unique part made from acrylic and gives it a flame- ...
'Darkfield' Lasers Let Mice Track On Glass |...
Darkfield Laser Tracking might sound like something the Death Star uses to find and kill pesky Rebel spaceships, but it is in ... Darkfield Lasers Let Mice Track On Glass. Darkfield Laser Tracking might sound like something the Death Star uses to find and ... Regular optical and laser mice track marks on the surface of the table, but glass is too flat and too see-through. The new ... Darkfield Laser Tracking might sound like something the Death Star uses to find and kill pesky Rebel spaceships, but it is in ...
Boffins sniff keystrokes with lasers, oscilloscopes • The Register
Boffins sniff keystrokes with lasers, oscilloscopes. I know what you typed last summer. By Dan Goodin 19 Mar 2009 at 23:30 ... An attacker can also use one line of sight to point the laser on the victim and a separate straight line to receive the signal ... The first method involves the use of laser microphones, which have long been the stuff of thrillers with spies who eavesdrop on ... Barisani, who was joined on stage by fellow Inverse Path colleague Daniele Bianco, said laser microphones can be trained on a ...
Laser | Encyclopedia.com
A laser is basically an intense beam of light. ... Laser Laser technologies are used for a wide range of purposes ... in laser-based products, including CD players, DNA screening machines, forensic tools, missile guiding devices, mapping and ... Gas lasers. Another common laser class is that of gas lasers, which includes helium neon (HeNe) lasers, carbon dioxide (CO2) ... Gas lasers. Another common laser class is that of gas lasers, which includes helium neon (HeNe) lasers, carbon dioxide (CO2) ...
WavelengthBeamPulseConventionalSpectralPhysicsPhotonicsFluorescenceEmissionWavelengthsLightDetectionTransmitPowerSystemPhotonicTypes of lasersExcimer lasersEmitSEARCHWorld'sPulsesCarbon dioxide lasersSemiconductorFemtosecondClass IIIbPicosecondNanosecondInertial ConfinHigh-powered lasersHelium-neonPrinciples of lasersApplication of lasersTunable1960PreciseTake lasersFiber lasersPowerful lasersPhotocoagulationSpectroscopyArgonRetinaRetinalRaman2001ErbiumApplicationsDermatologyCommonlyThalesProcessesTissueHeNeAtoms or moleculesUltrafastPeaked in 1989
- The example laser system shown below uses a quantum dot optical amplifier combined with one or two electro-optically tunable wavelength filters. (tue.nl)
- In the framework of the iPHOS FP7 EU project linear and ring dual wavelength lasers have been fabricated in the COBRA and Oclaro fabrication platforms for millimeter wave communications applications. (tue.nl)
- Narrow-linewidth and multi-wavelength lasers using our filtered feedback techniques and MMI-based integrated reflectors designed to simultaneously transmit at four different wavelengths, were shown to have good lasing characteristics. (tue.nl)
- Digitally tunable dual wavelength emission from semiconductor ring lasers with filtered optical feedback. (tue.nl)
- Semiconductor ring laser with on-chip filtered optical feedback for discrete wavelength tuning. (tue.nl)
- But also keep in mind that laser wavelength and power are only part of the equation the laser must be properly integrated and aligned into your system, or you will get suboptimal performance even with optimal excitation. (purdue.edu)
- A library for pulse lasers is also being developed for the generic integration platform. (tue.nl)
- The Mobius source was a customized G1R2 laser that was used to produce a comb spectrum of user-selectable visible wavelengths with approximately one nanosecond pulse duration and a 20 MHz repetition rate. (microscopy-news.com)
- As it turned out, some details of my claims, most notably my invoking Star Trek as a violator of laser physics, prompted a healthy discussion. (sfsignal.com)
- As a fictional technology, the foundations of phasers in physics are a bit shaky, but in concept, phasers would share some physical attributes with lasers. (sfsignal.com)
- MOUNTAIN VIEW, Calif., Oct. 27, 2011 - Mobius Photonics, an innovative producer of short pulsed fiber laser sources (IR, green, and UV laser), announces that its "G1R2" laser source has been used in super-resolution microscopy experiments at the Max Planck Institute for Biophysical Chemistry (Göttingen, Germany). (microscopy-news.com)
- Founded in 2005, Mobius Photonics, Inc. produces fiber-based laser sources for applications ranging from material processing for solar cell manufacturing, semiconductor fabrication and assembly, and flat panel display manufacturing, to scientific uses such as super-resolution microscopy. (microscopy-news.com)
- A word of caution, however if you are using a 561 nm laser to excite PE, the traditional 575/26 and 585/42 nm bandpass filters traditionally used for PE detection are too close to the 561 nm emission, and are not adequately blocked for this laser line. (purdue.edu)
- In our original Cytometry paper, we used a 610/20 nm bandpass to avoid the laser line this has proven to be a less-than-optimal choice, as it is too far shifted off the PE emission spectrum. (purdue.edu)
- We develop a scheme in which we use a laser operating at a discrete set of equally spaced wavelengths that can be matched to the internationally standardized telecommunication wavelengths (ITU-grid). (tue.nl)
- A photon is a particle (which lasers also emit) with mass, although it is extremely small, and a maser emits microwaves instead of light, although in practice it can emit wavelengths other than microwaves as well. (sfsignal.com)
- Our G1R2 laser allowed researchers to test and select optimum wavelengths for imaging samples expressing GFP. (microscopy-news.com)
- I ve also talked with several LSR II users who think they see high backgrounds in their FITC channel when exciting PE with a 532 nm laser, and the cause is definitely a FITC filter that insufficiently excludes green laser light. (purdue.edu)
- We ve since had several 590/20 nm filter made by Chroma and Semrock, and these are much more sensitive for PE while being compatible with 561 nm laser light. (purdue.edu)
- On a fundamental level, lasers are simply amplified light, but they exhibit some special properties that distinguish them from, say, the cold glow of the fluorescent tube over your head or the IKEA lamp in the corner. (sfsignal.com)
- Moving forward, remember one thing about lasers: they're made of light. (sfsignal.com)
- In the STW LWAVETECH project we focus on tunable lasers for gas detection based on an AWG laser and new interferometer lay-out structures. (tue.nl)
- Hello everyone I completely agree with Mario that a 532 nm green laser can certainly be compatible with FITC detection if the correct bandpass filter is used. (purdue.edu)
- We ve done some comparisons between 532 and 561 nm lasers for PE detection, which are also included in the linked document. (purdue.edu)
- Mach-Zehnder modulators integrated with these lasers could be operated up to 12.5 Gbps with output power up to 4 mW in the fiber. (tue.nl)
- I m attaching data (Telford_561nm_laser.pdf) where you can see a comparison between filters ranging from 575 nm to 610 nm, using 488, 532 and 561 nm laser sources (power-matched at 50 mW). (purdue.edu)
- 561 nm lasers at 50 mW improve PE sensitivity somewhat when compared to 532 nm at the same power level using our new 590/20 nm filter this is not too surprising if you look at the PE excitation spectrum, which peaks around 556-560 nm. (purdue.edu)
- But 561 nm lasers are now available at 100 mW, and higher power units are coming, so they should be comparable in power to the green very soon. (purdue.edu)
- It would seem using the words "Star Trek" and "lasers" in the same sentence is a cardinal mistake, as anyone even remotely familiar with the universe will tell you they harness the power of phasers, not lasers (duh). (sfsignal.com)
- We demonstrate an endoscopic imaging system for microscopic flow measurement (for example blood flow in tissue) using laser speckle contrast imaging. (mit.edu)
- Recently, however, the U.S. Navy declared its Laser Weapon System mounted aboard the USS Ponce ready for defensive use against drones. (sfsignal.com)
- Added Leonardo, "Building on our experience in super-resolution microscopy, Mobius has recently developed a new prototype laser that offers similar capabilities to our G1R2, but from an easier-to-use, longer life system. (microscopy-news.com)
- The result is a laser system designed to allow high-resolution image generation with fast acquisition times. (microscopy-news.com)
- Excimer lasers (the name is derived from the terms excited and dimers ) use reactive gases, such as chlorine and fluorine, mixed with inert gases such as argon, krypton or xenon. (howstuffworks.com)
- The ground-based laser-space mirror part of this effort built largely on DARPA efforts toward high-powered, gas-phase excimer lasers (that could emit in the shorter, more water-penetrating region of the electromagnetic spectrum) that had led to the demonstration of a workable, moderate power, laser-optical receiver combination. (darpa.mil)
- Excimer lasers would expand into medical arenas, especially for corrective eye surgery. (darpa.mil)
- Excimer lasers are powerful and versatile light sources in the UV range of the electromagnetic spectrum. (coherent.com)
- Lasik, microkeratomes and excimer lasers are flawed to begin with but at the bare minimum need to be labelled as the high risk devices for which they are. (fda.gov)
- CO2 lasers emit energy in the far-infrared, and are used for cutting hard materials. (howstuffworks.com)
- Class I - These lasers cannot emit laser radiation at known hazard levels. (howstuffworks.com)
- Class II - These are low-power visible lasers that emit above Class I levels but at a radiant power not above 1 mW. (howstuffworks.com)
- Laser rods are placed in each bullet hole found in the scene and activated to emit light. (encyclopedia.com)
- Then, as the high energy particles relax (drop to a lower energy level), they emit photons and, consequently, laser light. (popsci.com)
- The world's largest X-ray laser in Germany, promises to shed new light onto very small things by allowing scientists to penetrate the inner workings of atoms, viruses and chemical reactions. (forbes.com)
- world's most powerful laser pulses and it fits on a tabletop. (forbes.com)
- Today, just a handful of laser systems around the world with the requisite potential are the flagships of large-scale research facilities, like those in Japan and the United States - and in Germany where the world's strongest laser of its type, the European XFEL, is to be found in the Hamburg area. (innovations-report.com)
- Scientists at the University of Cambridge say the process involves short laser pulses to erase words and images by heating the printed material to the point that it vaporizes. (upi.com)
- A linear sequence of up to 12 laser pulses can be triggered at the touch of a button on the slit lamp joystick. (zeiss.com)
- Our drilling processes employ ultra-short laser pulses (in the picosecond range) that remove glass through nonlinear effects. (corning.com)
- The most powerful laser system in the world developed and installed by Thales in Romania with the capacity to deliver pulses with the record power level of 10 petawatts, was formally accepted on October 11, 2019 by our Customer, the National Institute of Physics and Nuclear Engineering Horia Hulubei (IFIN-HH). (thalesgroup.com)
- The Extreme Light Infrastructure for Nuclear Physics (ELI-NP) project in Romania recently reached on March 20, 2019 a significant milestone: the ultra-high intensity laser system developed by Thales has successfully generated its first pulses at a peak power level of 10 petawatts (PW) equivalent to 1016 watts : 10.9PW, at 1 shot/min compressed in a pulse just 22.3 femtoseconds long to be precise. (thalesgroup.com)
- Ruxin Li and his colleagues hope that they can make laser pulses that could rip apart empty space. (forbes.com)
- The robot shoots the leaves of the unwanted plants with short laser pulses, which causes a weakening in their vitality," reports Dr. Pastrana. (innovations-report.com)
Carbon dioxide lasers2
- Several manufacturers have received clearance for argon and carbon dioxide lasers to activate tooth-bleaching solutions and to treat gum disease. (fda.gov)
- The automobile industry makes extensive use of carbon dioxide lasers with powers up to several kilowatts for computer controlled welding on auto assembly lines. (gsu.edu)
- The laser medium can be a solid, gas, liquid or semiconductor . (howstuffworks.com)
- Degradation of the cleaved light output surface of a semiconductor crystal injection laser is reduced through control of surface recombination by providing an annealed optically transparent coating at least one ingredient of which has a higher bandgap than said crystal over the cleaved light output surface. (google.com)
- 1. In a semiconductor crystal laser of the type having an active lasing region in a laser crystal of semiconductor material essentially perpendicular to a cleaved light output surface, the improvement for reducing heating produced by carrier surface recombination at said cleaved surface comprising, an annealed coating of an optically transparent compound, at least one element thereof having a higher bandgap than that of said laser crystal. (google.com)
- 2. The laser of claim 1 wherein said semiconductor is selected from the group consisting of GaAs, GaAlAs and GaInAsP. (google.com)
- 4. In a semiconductor crystal injection laser having at least one cleaved light output surface and ohmic contacts on the surfaces perpendicular thereto, the improvement comprising an annealed optically transparent coating of a surface recombination control material, at least one ingredient of which has a bandgap greater than that of said semiconductor crystal covering said at least one cleaved surface. (google.com)
- 5. The improvement of claim 4 wherein said semiconductor crystal of said laser is selected from a group consisting of GaAs, GaAlAs and GaInAsP and said recombination control material is a member selected from the group consisting of ZnS, CdS, CdTe and CdSe. (google.com)
- The technical field of the invention is that of semiconductor injection lasers wherein an input current is converted to a coherent light output. (google.com)
- Injection lasers employ a semiconductor crystal of a binary or mixed compound of elements usually from group III and group V of the periodic table. (google.com)
- In these structures, a cleaved surface of the semiconductor crystal is employed as a partially reflecting mirror at the ends of the laser cavity. (google.com)
- Helium-neon and semiconductor lasers have become standard parts of the field surveyor's equipment. (gsu.edu)
- We are developing a semiconductor optical chip with a laser source that can achieve the tuning requirements for rapid spectral scanning and plan to integrate further OCT apparatus for full system-on-chip solutions. (tue.nl)
- Relaxation oscillation dynamics in semiconductor diode lasers with optical feedback. (tue.nl)
- Digitally tunable dual wavelength emission from semiconductor ring lasers with filtered optical feedback. (tue.nl)
- Semiconductor ring laser with on-chip filtered optical feedback for discrete wavelength tuning. (tue.nl)
- Coherent ultrashort pulse laser products include femtosecond lasers with up to 900 fs pulse widths and picosecond lasers with up to 80 MHz repetition rates. (coherent.com)
- Short-pulsed industrial lasers from nanosecond lasers with up to 1 Joule pulse energy, through picosecond lasers with up to 80 MHz repetition rates, to femtosecond lasers with up to 900 fs pulse widths. (coherent.com)
- In contrast, modern ultra-short picosecond and femtosecond pulse length lasers can remove material using a process called cold ablation. (sme.org)
- Four different 1064 nm laser diode (DFB, Bragg, BroadBragg and Multimode) are offered as stock items or associated with a CW or Pulsed (nanosecond) laser diode driver. (photonics.com)
- Diode pumped and flashlamp pumped nanosecond Lasers. (thalesgroup.com)
- Diod pumped and flash lamp pumped nanosecond Lasers. (thalesgroup.com)
- The main use for both lasers being the investigation into inertial confinement fusion, high energy density physics and nuclear weapons research. (wikipedia.org)
Principles of lasers1
- You learn the fundamental principles of lasers and their application in chemistry, chemical physics and biophysics. (sussex.ac.uk)
Application of lasers2
- Another useful application of lasers in forensic science is spectroscopy. (encyclopedia.com)
- Chemical and Biochemical Applications of Lasers aims to give a general introduction to as well as an evaluation of the successful application of lasers in various areas, especially in the fields of chemistry and biochemistry. (elsevier.com)
- In the STW LWAVETECH project we focus on tunable lasers for gas detection based on an AWG laser and new interferometer lay-out structures. (tue.nl)
- Advantages of that method is that no unusual doping or cooling is required, and it is tunable through the pump laser. (hpcwire.com)
- Tunable Lasers: Poised for Takeoff? (lightreading.com)
- In 1960, Theodore H. Maiman built the first laser at Hughes Research Laboratories. (newscientist.com)
- Lasers were first developed in 1960. (cincinnatichildrens.org)
- That seems only natural: laser weapons are a staple of modern video games, and ray-guns of various sorts were common in science fiction for decades before the first real-life laser was demonstrated in 1960. (scientificamerican.com)
- But specialists in defence and security are starting to take lasers seriously. (scientificamerican.com)
- With some of the most powerful lasers in the world the conditions found in the core of the Sun can be recreated in laboratories on Earth. (forbes.com)
- Numerous high quality contact lenses for therapeutic laser applications such as iridotomy, trabeculoplasty and retinal photocoagulation. (zeiss.com)
- Lasers are used for photocoagulation of the retina to halt retinal hemorrhaging and for the tacking of retinal tears. (gsu.edu)
- In diabetic maculopathy, direct ophthalmoscopy can reveal retinal exudates, but the degree of macula oedema, which usually underlies the decision to treat by laser photocoagulation, 1 is less clear. (bmj.com)
- Laser photocoagulation is eye surgery using a laser to shrink or destroy abnormal structures in the retina, or to intentionally cause scarring. (medlineplus.gov)
- Photocoagulation takes place by using the laser to create a microscopic burn in the target tissue. (medlineplus.gov)
- It is one of the most common eye diseases that needs laser photocoagulation. (medlineplus.gov)
- In laser photocoagulation for diabetic retinopathy, laser energy is aimed at certain areas of the retina to prevent abnormal vessels from growing or shrink those that may already be there. (medlineplus.gov)
- Special preparations are rarely needed before laser photocoagulation. (medlineplus.gov)
- Laser spectroscopy determine the molecular structure of materials and chemical compounds. (encyclopedia.com)
- Infrared laser spectroscopy can determine molecular structures of polymers on surfaces and gas phase ions, and is used to detect explosive components or illegal drugs in samples. (encyclopedia.com)
- Often more than one method is used to detect toxic industrial components present in the environment, such as coupling plasma mass spectrometry with laser spectroscopy. (encyclopedia.com)
- The complexity of the spectroscopy of uranium atoms and compounds may require incorporation of any number of available laser technologies. (globalsecurity.org)
- Differences between continuous wave and ultra-fast lasers are explored through applications to steady-time and time-resolved spectroscopy. (sussex.ac.uk)
- For these reasons, silicon is an ideal Raman medium at the mid-wave infrared for applications in fiber Raman lasers that are being developed to replace Erbium:YAG lasers, in lasers used for skin resurfacing, and in dentistry, to whiten teeth and to eliminate the need for mechanical tooth drilling. (hpcwire.com)
- laser technologies are being developed for a variety of applications. (cdc.gov)
- This conference is part of a continuing series dedicated to recent developments and applications of x-ray lasers and other coherent x-ray sources with attention to supporting technologies and instrumentation. (springer.com)
- Medical lasers have been used for dermatology applications such as removal of port wine stains, dark spots, tattoos, acne scars and other blemishes for over a decade. (fda.gov)
- Applications for and research on lasers in dentistry continues to expand since their introduction to the dental profession. (ada.org)
- Given the many factors that are appropriate to evaluate when using lasers in biological systems, the Council feels that the 510(k) process alone is not inherently sufficient to scientifically demonstrate safety, efficacy, or effectiveness for marketed dental laser applications in all cases. (ada.org)
- The CLT 500X is a laser processing workstation designed for high-precision applications in the glass, precision engineering, and electronics industries. (corning.com)
- Thales proposes a wide range of lasers solutions for the most demanding applications. (thalesgroup.com)
- Lasers today are being used in an ever-increasing number of applications. (merlot.org)
- We provide innovative laser weapon systems with 360 degree coverage for sea, land and air applications. (raytheon.com)
- One of the desired applications of this laser would be 'breaking the vacuum' which is where the laser would have enough energy to create electrons and positrons (antimatter equivalent of the electron) from empty space. (forbes.com)
- Silicon lasers are coming, and there will be many exciting applications beyond what is now being pursued, said Bahram Jalali, a University of California-Los Angeles electrical engineering professor, at an optoelectronics plenary session at Photonics West 2006. (hpcwire.com)
- The lasers also have potential applications in biochemical sensing in the defense industry, he said. (hpcwire.com)
- Monolithic optical isolators for laser applications are also highly desired, as are new ways to use silicon for coupling and packaging. (hpcwire.com)
- Coherent's diode-pumped solid-state (DPSS) portfolio includes pulsed and short-pulsed Q-switched, modelocked, and CW lasers that enable a wide range of materials processing, scientific, and life sciences applications. (coherent.com)
- This is a systematic, up-to-date guide to laser instrumentation for sensing and measurement in contemporary scientific, industrial, automotive and avionics applications. (oreilly.com)
- The text is recommended for chemists, biochemists, and chemical physicists who want to know more about lasers and its applications to their respective fields. (elsevier.com)
- Among its many accomplishments, Astanza is proud to be the exclusive tattoo removal laser provider for LaserAway , the Nation's Leader in Aesthetic Dermatology, and also a trusted laser provider for Homeboy Industries , the largest gang intervention and re-entry program and the #1 busiest laser tattoo removal provider in the world. (prnewswire.com)
- The recent expansion in laser dermatology is both promising and exciting as the treatments available to derms and their patients continue to grow. (modernmedicine.com)
- Our latest edition of the Thales Laser Masterclass training developped in partnership with the Polytech Paris-Sud and Paris-Sud University, has successfully been held this autumn. (thalesgroup.com)
- Selected again for NASA's Mars exploration programme, Thales has now delivered the laser for the SuperCam instrument to the French space agency CNES, which is partnering NASA for Mars 2020. (thalesgroup.com)
- Thales laser installation has started and the customer has witnessed the first lasing effects. (thalesgroup.com)
- Thales has been awarded the title of Laser of the Future by the French National Space Agency (Centre National d'Etudes Spatiales - CNES) whereby Thales has developped the laser for the SUPERCAM instrument intended for the 2020 mission to Mars. (thalesgroup.com)
- As a key player on the Scientific Laser Marketplace, Thales has a large R&D activity to constantly release innovative solutions on the markets. (thalesgroup.com)
- Thales is proud to mention that the Bella project won 2 world-class awards in 2012 and 2013 and that its laser activity was recognized as the most innovative technology within the group in 2014. (thalesgroup.com)
- We have established strong and long-term relation with well-known laboratories and partners ensuring smooth research to industry transfer of new processes and lasers concepts. (thalesgroup.com)
- Present systems for enrichment processes using lasers fall into two categories: those in which the process medium is atomic uranium vapor and those in which the process medium is the vapor of a uranium compound. (globalsecurity.org)
- Common nomenclature for such processes include "first category- atomic vapor laser isotope separation (AVLIS or SILVA)" and "second category- molecular laser isotope separation (MLIS or MOLIS). (globalsecurity.org)
- We are now advancing into areas that suggest the possibility of assisting these tunneling processes with strong X-ray lasers," says Schützhold. (innovations-report.com)
- As the benefits of smaller devices help improve the quality of life, the ability to manufacture these devices to the highest precision, reliability and traceability are more important than ever and laser micro-machining processes are playing a more important role. (sme.org)
- Are you interested in purchasing a soft-tissue laser within the next 6 months? (google.com)
- Several lasers have clearance for hard tissue use on teeth. (fda.gov)
- Lasers may be used to remove tissue in eye surgery as well. (fda.gov)
- Study co-author Professor Frederik Claeyssens said, 'This is the first time we have been able to structure polylactide with such high resolution and the first time that direct laser writing has been applied to tissue engineering. (medicalnewstoday.com)
- Since that time, lasers have improved and many new types of laser have been developed, including those that can clot, cut or get rid of tissue. (cincinnatichildrens.org)
- Changes or improvements to the skin have become more significant since lasers have the ability to reach deeper into the tissue than any other form of treatment. (bellaonline.com)