A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)
A tubular organ of VOICE production. It is located in the anterior neck, superior to the TRACHEA and inferior to the tongue and HYOID BONE.
A pair of cone-shaped elastic mucous membrane projecting from the laryngeal wall and forming a narrow slit between them. Each contains a thickened free edge (vocal ligament) extending from the THYROID CARTILAGE to the ARYTENOID CARTILAGE, and a VOCAL MUSCLE that shortens or relaxes the vocal cord to control sound production.
Congenital or acquired paralysis of one or both VOCAL CORDS. This condition is caused by defects in the CENTRAL NERVOUS SYSTEM, the VAGUS NERVE and branches of LARYNGEAL NERVES. Common symptoms are VOICE DISORDERS including HOARSENESS or APHONIA.
Total or partial excision of the larynx.
Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)
Procedures of applying ENDOSCOPES for disease diagnosis and treatment. Endoscopy involves passing an optical instrument through a small incision in the skin i.e., percutaneous; or through a natural orifice and along natural body pathways such as the digestive tract; and/or through an incision in the wall of a tubular structure or organ, i.e. transluminal, to examine or perform surgery on the interior parts of the body.
The mucous lining of the LARYNX, consisting of various types of epithelial cells ranging from stratified squamous EPITHELIUM in the upper larynx to ciliated columnar epithelium in the rest of the larynx, mucous GOBLET CELLS, and glands containing both mucous and serous cells.
Instruments for the visual examination of interior structures of the body. There are rigid endoscopes and flexible fiberoptic endoscopes for various types of viewing in ENDOSCOPY.
A protein extract of human menopausal urine in which LUTEINIZING HORMONE has been partially or completely removed. Urofollitropin represents FOLLICLE STIMULATING HORMONE from the urine.
A procedure involving placement of a tube into the trachea through the mouth or nose in order to provide a patient with oxygen and anesthesia.
Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER.
The vocal apparatus of the larynx, situated in the middle section of the larynx. Glottis consists of the VOCAL FOLDS and an opening (rima glottidis) between the folds.
Analysis of the HYDROGEN ION CONCENTRATION in the lumen of the ESOPHAGUS. It is used to record the pattern, frequency, and duration of GASTROESOPHAGEAL REFLUX.
Mobilization of the lower end of the esophagus and plication of the fundus of the stomach around it (fundic wrapping) in the treatment of GASTROESOPHAGEAL REFLUX that may be associated with various disorders, such as hiatal hernia. (From Dorland, 28th ed)
The muscular membranous segment between the PHARYNX and the STOMACH in the UPPER GASTROINTESTINAL TRACT.
INFLAMMATION, acute or chronic, of the ESOPHAGUS caused by BACTERIA, chemicals, or TRAUMA.
A group of carcinomas which share a characteristic morphology, often being composed of clusters and trabecular sheets of round "blue cells", granular chromatin, and an attenuated rim of poorly demarcated cytoplasm. Neuroendocrine tumors include carcinoids, small ("oat") cell carcinomas, medullary carcinoma of the thyroid, Merkel cell tumor, cutaneous neuroendocrine carcinoma, pancreatic islet cell tumors, and pheochromocytoma. Neurosecretory granules are found within the tumor cells. (Segen, Dictionary of Modern Medicine, 1992)
A publication issued at stated, more or less regular, intervals.
Individual's rights to obtain and use information collected or generated by others.
A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.
The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)
"The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.
The evaluation by experts of the quality and pertinence of research or research proposals of other experts in the same field. Peer review is used by editors in deciding which submissions warrant publication, by granting agencies to determine which proposals should be funded, and by academic institutions in tenure decisions.
Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription.
Regional infusion of drugs via an arterial catheter. Often a pump is used to impel the drug through the catheter. Used in therapy of cancer, upper gastrointestinal hemorrhage, infection, and peripheral vascular disease.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Unstable isotopes of fluorine that decay or disintegrate emitting radiation. F atoms with atomic weights 17, 18, and 20-22 are radioactive fluorine isotopes.
An imaging technique using compounds labelled with short-lived positron-emitting radionuclides (such as carbon-11, nitrogen-13, oxygen-15 and fluorine-18) to measure cell metabolism. It has been useful in study of soft tissues such as CANCER; CARDIOVASCULAR SYSTEM; and brain. SINGLE-PHOTON EMISSION-COMPUTED TOMOGRAPHY is closely related to positron emission tomography, but uses isotopes with longer half-lives and resolution is lower.
The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.
Created 7 April 1992 as a result of the division of Yugoslavia.
Neoplasms of the skin and mucous membranes caused by papillomaviruses. They are usually benign but some have a high risk for malignant progression.
A family of small, non-enveloped DNA viruses infecting birds and most mammals, especially humans. They are grouped into multiple genera, but the viruses are highly host-species specific and tissue-restricted. They are commonly divided into hundreds of papillomavirus "types", each with specific gene function and gene control regions, despite sequence homology. Human papillomaviruses are found in the genera ALPHAPAPILLOMAVIRUS; BETAPAPILLOMAVIRUS; GAMMAPAPILLOMAVIRUS; and MUPAPILLOMAVIRUS.
A type of ALPHAPAPILLOMAVIRUS especially associated with malignant tumors of the CERVIX and the RESPIRATORY MUCOSA.
Infections produced by oncogenic viruses. The infections caused by DNA viruses are less numerous but more diverse than those caused by the RNA oncogenic viruses.
Tumors or cancer of the UTERINE CERVIX.
Neoplasms composed of glandular tissue, an aggregation of epithelial cells that elaborate secretions, and of any type of epithelium itself. The concept does not refer to neoplasms located in the various glands or in epithelial tissue.
A device, activated electronically or by expired pulmonary air, which simulates laryngeal activity and enables a laryngectomized person to speak. Examples of the pneumatic mechanical device are the Tokyo and Van Hunen artificial larynges. Electronic devices include the Western Electric electrolarynx, Tait oral vibrator, Cooper-Rand electrolarynx and the Ticchioni pipe.
Techniques, procedures, and therapies carried out on diseased organs in such a way to avoid complete removal of the organ and preserve the remaining organ function.
Methods of enabling a patient without a larynx or with a non-functional larynx to produce voice or speech. The methods may be pneumatic or electronic.
A method of speech used after laryngectomy, with sound produced by vibration of the column of air in the esophagus against the contracting cricopharyngeal sphincter. (Dorland, 27th ed)

Elevation of the epidermal growth factor receptor and dependent signaling in human papillomavirus-infected laryngeal papillomas. (1/1167)

Laryngeal papillomas are benign tumors caused by human papillomaviruses types 6 and 11. This study addressed alterations in levels of signal transduction from the epidermal growth factor receptor (EGFR) in papillomas and cultured papilloma cells compared to normal tissue and cells. Mitogen-activated protein kinase (MAPK) was activated to a greater extent, phosphotyrosine was more abundant, and EGFR was overexpressed in laryngeal papillomas compared to normal laryngeal epithelium by Western blot analysis. The EGFR was 3 times more abundant in cultured papilloma cells than in normal laryngeal cells by Scatchard analysis and Western blot, without gene amplification or an increase in steady-state levels of mRNA. Following stimulation with EGF, a significant portion of the EGFR was recycled to the surface in papilloma cells, whereas in normal cells, it was not. Tyrosine kinase activity and activation of MAPK was more responsive to epidermal growth factor stimulation in papilloma cells than in uninfected primary laryngeal cells. PD153035, a specific inhibitor of the EGFR, and an EGFR-specific antibody that blocks ligand binding completely abrogated basal MAPK activation by endogenous ligands in laryngeal papilloma cells. These results demonstrated that infection of laryngeal epithelium by low-risk human papillomaviruses elevates the EGFR by posttranslational mechanisms, increasing its responsiveness to ligand-mediated activation. They also showed that MAPK activation in laryngeal papillomas depends upon ligand-mediated EGFR stimulation.  (+info)

Glutathione S-transferase GSTM3 and GSTP1 genotypes and larynx cancer risk. (2/1167)

Glutathione S-transferases (GSTs) are involved in detoxification of reactive metabolites of carcinogens and, therefore, could be potentially important in susceptibility to cancer. The associations between larynx cancer risk and GSTM3 and GSTP1 gene polymorphisms, either separately or in combination with GSTM1 and GSTT1 gene polymorphisms, were evaluated using peripheral blood DNA from 129 cancer patients and 172 controls, all regular smokers. The frequencies of GSTM3 AA, AB, and BB genotypes were 60.5%, 36.4%, and 3.1% in cases and 72.7%, 24.4%, and 2.9% in controls, respectively. The frequencies of GSTP1 AA, AG, and GG genotypes were 48.1%, 40.3%, and 11.6% in cases and 50.0%, 37.2%, and 12.8% in controls, respectively. Multivariate logistic regression analyses did not reveal any association between the GSTP1 (AG or GG) genotype and larynx cancer [odds ratio, 1.1; 95% confidence interval (CI), 0.7-2.0]. In contrast, a significant increase in risk was related to the GSTM3 (AB or BB) genotype (odds ratio, 2.0; 95% CI, 1.1-3.4). The combined GSTM3 (AB or BB) and GSTM1-null genotype conferred a 4-fold risk (95% CI, 1.6-10.1) of larynx cancer as compared with the combined GSTM3 AA and GSTM1-positive genotype. However, the effect of GSTM3 (AB or BB) genotype was similar among individuals with GSTM1-positive or GSTM1-null genotypes.  (+info)

Concordant induction of cyclin E and p21cip1 in differentiated keratinocytes by the human papillomavirus E7 protein inhibits cellular and viral DNA synthesis. (3/1167)

Productive infections by human papillomaviruses (HPVs) occur only in differentiated keratinocytes in squamous epithelia in which the HPV E7 protein reactivates the host DNA replication machinery to support viral DNA replication. In a fraction of the differentiated keratinocytes, E7 also posttranscriptionally induces p21Cip1, which is distributed in a mutually exclusive manner with unscheduled cellular DNA synthesis. In this study, double immunofluorescence labeling unexpectedly revealed that E7 caused a concordant accumulation of both cyclin E and p21Cip1 to high levels in patient papillomas and in organotypic cultures of primary human keratinocytes. The induction of cyclin E is mutually exclusive with unscheduled cellular DNA synthesis or abundant viral DNA. These novel virus-host interactions in differentiated keratinocytes are in contrast to previous observations made in submerged proliferating cultures, in which HPV E7 induces cyclin E and overcomes p21Cip1 inhibition of S-phase entry. We propose that an appropriately timed induction of cyclin E/cyclin-dependent kinase 2 by HPV E7 in postmitotic cells enables S-phase reentry and HPV DNA amplification, whereas prematurely induced cyclin E stabilizes p21Cip1 protein, which then inhibits cyclin E/cyclin-dependent kinase 2. Consequently, cyclin E and p21Cip1 both fail to turn over, and DNA synthesis does not occur.  (+info)

Preradiotherapy computed tomography as a predictor of local control in supraglottic carcinoma. (4/1167)

PURPOSE: To determine the utility of pretreatment computed tomography (CT) for predicting primary site control in patients with supraglottic squamous cell carcinoma (SCC) treated with definitive radiotherapy (RT). MATERIALS AND METHODS: Pretreatment CT studies in 63 patients were reviewed. Minimum length of follow-up was 2 years. Local recurrence and treatment complications resulting in permanent loss of laryngeal function were documented. Tumor volume was calculated using a computer digitizer, and pre-epiglottic space (PES) spread was estimated. The data were analyzed using a combination of Fisher's exact test, logistic regression modeling, and multivariate analyses. Five-year local control rates were calculated using the product-limit method. RESULTS: Local control rates were inversely and roughly linearly related to tumor volume, although there seemed to be a threshold volume at which primary site prognosis diminished. Local control was 89% in tumors less than 6 cm3 and 52% when volumes were > or =6 cm3 (P = .0012). The likelihood of maintaining laryngeal function also varied with tumor volume: 89% for tumors less than 6 cm3 and 40% for tumors > or =6 cm3 (P = .00004). Pre-epiglottic space involvement by tumor of > or =25% was associated with a reduced chance of saving the larynx (P = .0076). Multivariate analyses revealed that only tumor volume independently altered these end points. CONCLUSION: Pretreatment CT measurements of tumor volume permits stratification of patients with supraglottic SCC treated with RT alone (which allows preservation of laryngeal function) into groups in which local control is more likely and less likely. Pre-epiglottic space spread is not a contraindication to using RT as the primary treatment for supraglottic SCC.  (+info)

Sternothoracotomy for combined coronary artery bypass grafting and left upper lobectomy in a patient with low-lying tracheostoma. (5/1167)

A 64-year-old man had a low-lying tracheostoma and presented with unstable angina and a mass in the pulmonary left upper lobe. Simultaneous coronary revascularization and resection of the lung neoplasm were completed through a sternothoracotomy (clam-shell) incision. The advantages of this approach include excellent exposure to the mediastinum and the lung fields, and the option of using both internal thoracic arteries for bypass grafting.  (+info)

Suppression of extracellular signals and cell proliferation by the black tea polyphenol, theaflavin-3,3'-digallate. (6/1167)

Previous studies in our laboratory have shown that the major green tea polyphenol, (-)-epigallocatechin-3-gallate (EGCG), suppressed autophosphorylation of epidermal growth factor (EGF) receptor induced by EGF in human A431 epidermoid carcinoma cells. In this study, we examined the inhibitory effects of black tea polyphenols, including theaflavin (TF-1), a mixture (TF-2) of theaflavin-3-gallate (TF-2a) and theaflavin-3'-gallate (TF-2b), theaflavin-3,3'-digallate (TF-3) and the thearubigin fraction on the autophosphorylation of the EGF and PDGF receptors in A431 cells and mouse NIH3T3 fibroblast cells, respectively. First, we examined the effects of these polyphenols on the proliferation of A431 and NIH3T3 cells. Both EGCG and TF-3 strongly inhibited the proliferation of A431 and NIH3T3 cells more than the other theaflavins did. In cultured cells with pre-treatment of tea polyphenol, TF-3 was stronger than EGCG on the reduction of EGF receptor and PDGF receptor autophosphorylation induced by EGF and PDGF, respectively. Other theaflavins slightly reduced the autophosphorylation of the EGF and PDGF receptors; furthermore, TF-3 could reduce autophosphorylation of the EGF receptor (or PDGF receptor) even with co-treatment with EGF (or PDGF) and TF-3, but EGCG was inactive under these conditions. In addition, TF-3 was stronger than EGCG in blocking EGF binding to its receptor. These results suggest that not only the green tea polyphenol, EGCG, but also the black tea polyphenol, TF-3, have an antiproliferative activity on tumor cells, and the molecular mechanisms of antiproliferation may block the growth factor binding to its receptor and thus suppress mitogenic signal transduction.  (+info)

The difference between delayed extubation and tracheostomy in post-operative sleep apnea after glossectomy or laryngectomy. (7/1167)

BACKGROUND: Patients with cancer of the tongue or larynx require glossectomies or laryngectomies and subsequent reconstruction. These procedures remove part of the patient's upper airway. In cancer of the tongue, the removed part of the airway is substituted by a flap of their skin. Post-operatively, it is possible that the patients have problems respiring comfortably. In addition to this, long surgical procedures may simply interfere with their circadian rhythm. To elucidate the possible change in their post-operative respiration, we monitored the patient's respiratory pattern with an apnea monitor. METHODS: We attached an apnea monitor to the patients and recorded their respiratory pattern and arterial oxygen saturation. The patients were monitored for a total of five days: three days prior to the operation, one day before the operation, the day of operation, two days after, and on the fourth day after the operation. The period of monitoring was from 8:00 p.m. to 6:00 a.m. the next morning. RESULTS: Sixteen patients completed this study. The patients whose tube was extubated after glossectomy showed frequent apnea, low mean oxygen saturation and low comfort score as compared to the patients with tracheostomy after laryngectomy. Because two failed cases of free skin flap were among the former, it is possible that the frequent apnea is a factor of failed free skin graft after glossectomy and laryngectomy. CONCLUSION: Further studies are required to improve the patient's respiration during their sleep after tracheal extubation in glossectomy.  (+info)

Differential protection against benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced DNA damage in HepG2 cells stably transfected with allelic variants of pi class human glutathione S-transferase. (8/1167)

The pi class glutathione S-transferase (GSTP1-1), which is polymorphic in human populations, is believed to play an important role in detoxification of the ultimate carcinogen of widespread environmental pollutant benzo[a]pyrene [(+)-anti-benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide [(+)-anti-BPDE]]. The allelic variants of human GSTP1-1 (hGSTP1-1) differ in their structures by the amino acids in positions 104 (isoleucine or valine) and/or 113 (valine or alanine). Here, we have determined the protective effect of overexpression of allelic variants of hGSTP1-1, through stable transfection in HepG2 cells, against (+)-anti-BPDE-induced DNA modification. Clonal transfectants of HepG2 cells corresponding to the three allelic variants of hGSTP1-1 [(I104,A113), (V104,A113), and (V104,V113), denoted hGSTP1(IA), hGSTP1(VA), and hGSTP1(VV), respectively] with similar levels of hGSTP1 protein were identified and characterized for their GST activity and (+)-anti-BPDE-induced DNA modification. The glutathione S-transferase activity toward (+)-anti-BPDE was significantly higher (approximately 3.0-3.6-fold) in cells transfected with hGSTP1(VA) [HepG2(VA)] and hGSTP1(VV) [HepG2(VV)] compared with hGSTP1(IA) transfectant [HepG2(IA)]. The formation of (+)-anti-BPDE-DNA adducts was significantly reduced in HepG2(VA) and HepG2(VV) cells compared with cells transfected with insert-free vector (HepG2-vect). Maximum protection against (+)-anti-BPDE-induced DNA damage was afforded by the hGSTP1(VV) isoform. The results of this study indicate that the allelic variants of hGSTP1-1 significantly differ in their ability to provide protection against (+)-anti-BPDE-induced DNA damage. Thus, hGSTP1-1 polymorphism may be an important factor in differential susceptibility of individuals to tumorigenesis induced by benzo[a]pyrene.  (+info)

Philippine General Hospital, University of the Philippines Manila. Objective. This study aims to determine the prevalence and pattern of thyroid gland involvement in advanced laryngeal squamous cell carcinoma and to identify factors associated with its development.. Method. Records of 118 patients who underwent laryngectomy with thyroidectomy for advanced laryngeal squamous cell carcinoma in a tertiary government hospital from January 2010 to August 2015 were reviewed. Demographic, clinical and histopathology data were obtained. The relationship of the laterality of primary tumor bulk and lobe involvement was analyzed using Fischers exact test. The association between thyroid gland invasion and other factors was analyzed using logistic regression.. Results. Thyroid gland involvement was found in 11% of the patients via direct spread in 92.3%. Single lobe involvement accounted for 61.5% of cases. There is a tendency for laryngeal squamous cell carcinoma to invade the thyroid lobe ipsilateral to ...
TY - JOUR. T1 - Immunohistochemical expression patterns of the HER4 receptors in normal mucosa and in laryngeal squamous cell carcinomas: Antioncogenic significance of the HER4 protein in laryngeal squamous cell carcinoma. AU - Paludetti, Gaetano. AU - Almadori, Giovanni. AU - Pitocco, Dario. AU - Bussu, Francesco. AU - Ranelletti, Franco Oreste. AU - Gessi, Marco. AU - Graziani, Cristina. AU - Lanza, Paola. AU - Lauriola, Libero. PY - 2012. Y1 - 2012. N2 - OBJECTIVES/HYPOTHESIS.: The prognosis for laryngeal squamous cell carcinoma (LSCC) has not shown any improvement in the last 30 years because of inadequate prognostic stratification. Therefore, the detection of reliable molecular markers may have a significant impact on clinical practice. As promising data regarding HER1/EGFR have been published, the purpose of the present study was to elucidate the role of the other receptors of the HER family. STUDY DESIGN: Retrospective. METHODS.: We used quantitative immunohistochemistry to evaluate the ...
Epidermal growth factor receptor (EGFR) is a tyrosine kinase molecule associated to the initial stages of neoplastic transformation. High expression of EGFR is connected to aggressive tumor behavior and high risk of metastasis and treatment failure. The aim of our study was to analyze the immunohistochemical expression of EGFR in 38 cases of laryngeal squamous cell carcinomas depending on clinicopathological parameters related to prognosis. The EGFR immunoreactions have statistical significant higher values in high grade carcinomas. Although the EGFR values were superior in advanced stages lesions, the aspect was not significant EGFR may be useful in identifying the aggressive laryngeal squamous carcinomas.
The aim of the present study was to identify specific serum miRNAs (preoperative serum samples compared to healthy controls) as potential diagnostic markers for detection in laryngeal squamous cell carcinoma (LSCC). Serum samples obtained from 66 patients with LSCC were compared with 100 healthy control subjects. Additionally, miRNA levels were evaluated to identify possible correlations with clinicopathological features. The expression of 377 miRNAs (screening set) was evaluated by microarray screening. The most differentially expressed miRNAs were validated by high-throughput real-time quantitative polymerase chain reaction (RT-qPCR) in the group of LSCC patients and healthy controls. Receiver-operator characteristic (ROC) curve analysis was conducted to evaluate the diagnostic accuracy of the highly and significantly identified deregulated miRNA(s) as potential candidate biomarker(s). According to the array analysis, eleven miRNAs revealed an altered expression profile. The levels of serum expression
The presence of Lymph node metastasis with extranodal extension (ENE) is considered to be an important adverse prognostic factor for survival in patients with head and neck cancer. The aim of this study was to determine the prognostic significance of ENE in patients with laryngeal squamous cell carcinoma (LSCC). Three hundred and fifty-five patients with LSCC who underwent surgical resection and neck dissection were included. The status of cervical lymph node was classified into three groups: pathological negative nodal (pN-), pathological positive nodal without ENE (ENE-), and pathological positive nodal with ENE (ENE+). A total of 85 of 355 (23.9%) LSCC were pathological nodal positive, and ENE was detected in 22/355 (6.2%) patients. ENE was associated with drinking (p=0.005), T stage (p=0.000), tumor location (p=0.000), and differentiation degree (p=0.000). The number of lymph node metastasis in ENE+ group was associated with almost twice compared to ENE- group (p=0.005). The 5-year overall ...
Laryngeal squamous cell carcinomas (LSCC) are frequently occurring cancers with a high risk of local recurrences or second primary tumours developing within the first two years of diagnosis. A common feature of LSCC is the epigenetic inactivation of certain genes by promoter hypermethylation. In a previous study we found associations of promoter methylation with some clinical features of LSCC. The present study aimed at assessing promoter hypermethylation of CDKN2A, MGMT and MLH1 as prognostic factors in LSCC patients. ...
Laryngeal squamous cell carcinomas (LSCC) are frequently occurring cancers with a high risk of local recurrences or second primary tumours developing within the first two years of diagnosis. A common feature of LSCC is the epigenetic inactivation of certain genes by promoter hypermethylation. In a previous study we found associations of promoter methylation with some clinical features of LSCC. The present study aimed at assessing promoter hypermethylation of CDKN2A, MGMT and MLH1 as prognostic factors in LSCC patients. ...
Laryngeal squamous cell carcinoma (LSCC) is a common malignant tumor in Northeast China and is frequently associated with well-established risk factors like smoking and alcohol abuse. Human papilloma
Prognostic value of cell-cycle regulators and cellular biomarkers in laryngeal squamous cell carcinoma | Menha Swellam; Lobna R. Ezz El-Arab; Ahmed Adly | download | BookSC. Download books for free. Find books
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This page includes the following topics and synonyms: Laryngeal Neoplasm, Laryngeal Tumor, Vocal Cord Cancer, Squamous Cell Carcinoma of the Larynx, Laryngeal Cancer, Laryngeal Squamous Cell Carcinoma.
The presence of RBP protein 48 positive papilloma virus morte slowly positive cases was associated with hpv and larynx cancer recurrence in 29 cases The presence of TGF protein 41 positive and slowly positive cases was associated with hpv and larynx cancer recurrence hpv and larynx cancer 18 cases The presence of HPV capsid protein 14 positive cases was associated with local recurrence in nine cases Figure 6. Unele studii au arătat că, în anumite cazuri hpv cancer larynx cancer laringian de etiologie HPV, genomul viral se integrează în materialul genetic al celulelor tumorale, hpv cancer larynx proteina p16 INK4A este supraexprimată în aceste cazuri, din cauza blocării proteinei pRb, ca rezultat al acțiunii proteinei virale E7 9, Totuși, privind în ansamblu situația, implicarea Hpv cancer larynx în apariția cancerelor laringiene este relativ restrânsă, însă infecția cu tulpina hpv cancer larynx este hpv laryngeal cancer corelată hpv laryngeal cancer predispoziția dezvoltării
Purpose: The objective of this study is to show the accumulation of bile acids in laryngeal tissues of laryngeal carcinoma patients. Materials and Methods: The present study compared the total bile acid level in the hypopharyngeal tissue, tumor tissue, and blood of 21 primary laryngeal carcinoma patients (study group) to that in the hypopharyngeal tissue and blood of 15 patients with benign laryngeal lesions (control group). Results: The total bile acid level was significantly higher in the tumor and hypopharyngeal tissues of the study group than in the hypopharyngeal tissues of the control group; however, the difference in the blood total bile acid level between the 2 groups was not significant. Conclusion: Bile acids in reflux material accumulate in the laryngeal tissue in laryngeal carcinoma patients; therefore, bile acids should be considered a carcinogenic factor in the etiology of laryngeal carcinoma because of their mutagenicity due to DNA breaking, as they cause chronic inflammation due ...
Background: Laryngeal cancer is an important malignancy in head and neck area and squamous cell carcinoma(SCC) is the most common type accounting for 95% of cases. Increase in matrix metalloproteinases (MMPs) indifferent tumors and their correlation with tumor invasiveness has been documented. However, most studieshave evaluated MMP-2 and MMP-9 expression and few have evaluated serum levels. The aim of current studywas to evaluate serum levels in patients with laryngeal SCC compared to normal subjects and assess any relationwith tumor clinicopathological findings. Materials and Methods: In this case control study, 20 patients with oralSCC and 20 healthy subjects were included. Serum levels of MMP-2 and MMP-9 were compared between groupsand correlations with findings including grade (T) and node involvement (N) were evaluated. Results: Patientswith laryngeal SCC had significantly higher serum levels of MMP-2 (p=0.01) and MMP-9 (p=0.03) comparedto healthy subjects. Patients with higher T stage (T3,4) had
WEDNESDAY, Dec. 14, 2016 (HealthDay News) - For patients with laryngeal squamous cell carcinoma (SCC), factors predictive of recurrence include neck metastasis at presentation and nonsurgical treatment, according to a study published online Nov. 30 in Head & Neck.. Aaro Haapaniemi, M.D., from Helsinki University Hospital in Finland, and colleagues analyzed a nationwide laryngeal SCC cohort from Finnish university hospitals during 2001 to 2005. Data were included for 316 patients with initial successful therapy.. The researchers found that 22 percent of patients had laryngeal SCC recurrence. The median time to recurrence was nine months, and 90 percent occurred within 36 months following treatment. Independent prognostic factors for recurrence included the World Health Organization performance status ,0, neck metastasis at presentation, and nonsurgical treatment. Five-year overall survival was 53 percent for patients with local recurrence and 5 percent for patients with regional/distant ...
Accumulating evidence has confirmed that miR-196a plays a critical role in tumorigenesis and tumor progression in a variety of cancers. It has been demonstrated that miR-196a is highly up-regulated in laryngeal cancer by miRNA profiling analysis. However, the functional mechanism of miR-196a in laryngeal cancer remains unclear. This study aims to explore the mechanism of miR-196a in laryngeal cancer. In the present study, we conducted qPCR analysis of miR-196a expression in human laryngeal cancer and showed that miR-196a was overexpressed in tumor-derived samples and laryngeal cancer cell lines compared with matched normal controls. Further functional analysis of miR-196a demonstrated that the inhibition of miR-196a could inhibit laryngeal cell-cycle progression and proliferation in vitro. Luciferase reporter assay and western blot confirmed that miR-196a directly targeted p27kip1. Moreover, in order to investigate whether miR-196a regulated cell growth in laryngeal cancer cells by targeting p27kip1,
Subsequently, the use of endoscopy was chosen for diagnosis, and an attempt was made to excise the mass. Intravenous etomidate (1mg kg-1), midazolam (0.5mg kg-1) and lidocaine (1mg kg-1), combined in the same syringe, were used for anesthetic induction. Anesthetic maintenance was performed with isoflurane, initially with a mask because orotracheal intubation was impossible, and then, a tracheostomy was performed, thus stabilizing the cardiorespiratory parameters for the procedure.. During the endoscopic procedure, a 10mm rigid endoscope/ nephroscope 5mm with a working channel, 5-mm atraumatic Babcock forceps, bipolar cutting and bipolar coagulation forceps (LinaTripolPowerBlade(r), WEM & VIVAMED, RibeirãoPreto, SP, Brazil) were used. The instruments were inserted through the mouth, and after reaching the larynx, the mass was observed in the laryngeal lumen, confirming the radiographic findings. The areas where the mass adhered to the laryngeal mucosa were found using the forceps, and a surgical ...
Preoperative neutrophil-to-lymphocyte ratio is an independent prognostic marker in patients with laryngeal squamous cell carcinoma. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
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E-mail: [email protected], [email protected] Abstract. Salmonella entericais an ultimative human pathogen that causes various health problems. On the other hand, Lactobacillus plantarumhas numerous positive effects on human health. The objective of this study was to investigate the influence of enterobacteriaS. entericaLT21 on human laryngeal carcinoma cell line (HEp2). The ability of the adhesion of S. entericaLT21 as an independent culture and in combination with L. plantarum16.4 to HEp2 cells was tested as well as metabolic activity of S. entericaLT21 after adhesion to HEp2 cells. The protein content in HEp2 cells after the incubation with S. entericaLT21 was investigated and compared with the protein content in the untreated HEp2 cells. Adhesion results show better binding of S. entericaLT21 than L. plantarum16.4 when bacteria are mixed in a 1:1 and 10:1 ratios, respectively. Acetic and lactic acid in the sample of HEp2 cells incubated with S. entericaLT21 were detected, as well as lactic ...
Risk factors for laryngeal cancer include smoking, alcohol, smoking and alcohol combined, asbestos and sulphuric acid. Learn about laryngeal cancer risk.
Personalized treatment strategies for laryngeal cancer based on tumor response after a single cycle of neoadjuvant chemotherapy ups survival.
TY - JOUR. T1 - Improving decision making in larynx cancer by developing a decision aid. T2 - A mixed methods approach. AU - Petersen, Japke F.. AU - Berlanga, Adriana. AU - Stuiver, Martijn M.. AU - Hamming-Vrieze, Olga. AU - Hoebers, Frank. AU - Lambin, Philippe. AU - van den Brekel, Michiel W. M.. PY - 2019/12. Y1 - 2019/12. KW - Patient decision aid. KW - counseling. KW - health communication. KW - larynx cancer. KW - chemoradiotherapy. KW - radiotherapy. KW - laryngectomy. KW - PATIENT-REPORTED OUTCOMES. KW - TOTAL LARYNGECTOMY. KW - NECK-CANCER. KW - SURVIVAL. KW - PRESERVATION. KW - QUALITY. KW - INFORMATION. KW - VALIDATION. KW - RADIATION. KW - TRENDS. U2 - 10.1002/lary.27800. DO - 10.1002/lary.27800. M3 - Article. VL - 129. SP - 2733. EP - 2739. JO - Laryngoscope. JF - Laryngoscope. SN - 0023-852X. IS - 12. ER - ...
BACKGROUND The aetiology and factors leading to the progression of laryngeal cancer are still unclear. Although human papillomavirus (HPV) has been suggested to play a role, reports concerning the effect of HPV infection on tumour development are controversial. Recently, transfusion transmitted virus (TTV) was suggested to play a role in certain infections as a causative or coinfecting agent. AIMS To investigate whether the development and progression of laryngeal squamous cell carcinoma is associated with coinfection with TTV and HPV. METHODS The prevalence of TTV and HPV was investigated using the polymerase chain reaction in tissue samples from 40 healthy individuals, 10 patients with recurrent papillomatosis, five patients with papillomatosis with malignant transformation, and 25 patients with laryngeal carcinoma. The obtained prevalence data were compared and analysed statistically. RESULTS In the 11 patients with carcinoma who had metastasis or relapse there was a high rate of coinfection
From BioPortfolio: DelveInsight Larynx Cancer Epidemiology Forecast To 2023 provides an overview of the epidemiology trends of Larynx Cancer in seven major markets US, France, Ger...
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Background: Laryngeal squamous cell carcinoma (LSCC) is among the most prevalent cancer tumor types in the globe. and EZH2 in both LSCC tissue and adjacent regular laryngeal tissue. Chi-square check, univariate analysis, and multivariate analysis were conducted to statistically measure the clinical need for EZH2 and USP7. Conclusions: USP7and EZH2 impacts LSCC progression; USP7 and EZH2 had been upregulated in LSCC cells, that may serve as 3rd party prognostic predictors, and potential restorative focuses on for LSCC. valuevaluevalue /th th colspan=2″ align=middle rowspan=1″ Multivariate evaluation /th th colspan=2″ align=middle rowspan=1″ hr / /th th align=middle rowspan=1″ colspan=1″ Harzard Percentage /th th align=middle rowspan=1″ colspan=1″ 95% CI /th /thead Lymphatic invasionNegative/Positive 0.0012.6051.534-4.423pTNMI + II/III + IV0.2340.7110.406-1.246USP7Bad/Positive0.0034.3381.639-11.477EZH2Bad/Positive0.0332.1301.063-4.269 Open up in another window ...
Patients with comorbidities do not receive optimal treatment for their cancer, leading to lower cancer survival. Information on individual comorbidities is not straightforward to derive from population-based administrative health datasets. We described the development of a reproducible algorithm to extract the individual Charlson index comorbidities from such data. We illustrated the algorithm with 1,789 laryngeal cancer patients diagnosed in England in 2013. We aimed to clearly set out and advocate the time-related assumptions specified in the algorithm by providing empirical evidence for them.. METHODS ...
The clinical management of head and neck squamous cell carcinoma (HNSCC) commonly involves chemoradiotherapy, but recurrences often occur that are associated with radioresistance. Using human SQD9 laryngeal squamous cell carcinoma cancer cells as a model, we aimed to identify metabolic changes associated with acquired radioresistance. In a top-down approach, matched radiosensitive and radioresistant SQD9 cells were generated and metabolically compared, focusing on glycolysis, oxidative phosphorylation (OXPHOS) and ROS production. The cell cycle, clonogenicity, tumor growth in mice and DNA damage-repair were assessed. Mitochondrial DNA (mtDNA) was sequenced. In a bottom-up approach, matched glycolytic and oxidative SQD9 cells were generated using FACS-sorting, and tested for their radiosensitivity/radioresistance. We found that acquired radioresistance is associated with a shift from a glycolytic to a more oxidative metabolism in SQD9 cells. The opposite was also true, as the most oxidative fraction
Laryngeal squamous cell carcinoma (LSCC) is the most common form of malignant disease in the head and neck region characterized by the frequent occurrence of metastases in the neck lymph nodes early in the disease progression. This form of cancer is characterised with numerous genetic abnormalities and changes in expression levels of proteins and glycoproteins associated with the process of carcinogenesis. Despite numerous findings molecular mechanism of metastatic disease has not yet been fully elucidated. In addition, there is increasing evidence that abnormal expression and glycosylation of proteins result of initial malignant transformation of cells, and aberrant glycosylation is one of the key events in the invasion and metastasis of many malignant diseases. In addition, there is increasing evidence indicating that abnormal expression and glycosylation of proteins is a result of cellular initial malignant transformation, and aberrant glycosylation is one of the key events in the invasion ...
EGFR Mutation and hematopoietic and lymphoid system neoplasm as inclusion criteria, 1 is phase 1 (1 open) [5]. EGFR Mutation is an inclusion criterion in 1 clinical trial Fax // +1.202.887.5093, © 2020 American Association for Clinical Chemistry. closed. trials that contain Of the trial that contains The disadvantage, of course, is that the assay will only detect those specific mutations targeted by the assay. are [4]. EGFR Mutation and laryngeal squamous cell carcinoma as inclusion criteria, 1 is phase 2 (1 open) [5]. trial that contains EGFR Mutation is an inclusion criterion in 1 clinical trial +. EGFR Mutation is an inclusion criterion in 1 clinical trial EGFR Mutation is an inclusion criterion in 1 clinical trial are open and 1 EGFR Mutation and liposarcoma as inclusion criteria, 1 is phase 1/phase 2 (1 open) [5]. for oropharyngeal squamous cell carcinoma, of which 2 EGFR Mutation is an inclusion criterion in 1 clinical trial Liu X, Jian X, and Boerwinkle E. dbNSFP: A lightweight database ...
The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above. General Information About Laryngeal Cancer. Updated statistics with estimated new cases and deaths for 2017 (cited American Cancer Society as reference 1).. Treatment Option Overview for Laryngeal Cancer. Added subsection title and text to state that surgery and radiation therapy have been the standards for treatment of laryngeal cancer but outcome data from randomized trials are limited; underpowered studies have not fully addressed whether to use surgery or radiation (cited Iyer et al. as reference 1). Also added that selection of primary surgery versus radiation therapy-based treatment should be made in a multidisciplinary setting with consideration of disease stage, comorbidities, and functional status, including voice and swallowing outcomes and lung capacity.. Added text to state that prospective ...
TY - JOUR. T1 - Treatment and survival in 10,429 patients with localized laryngeal cancer. T2 - A population-based analysis. AU - Misono, Stephanie. AU - Marmor, Schelomo. AU - Yueh, Bevan. AU - Virnig, Beth A.. PY - 2014/6/15. Y1 - 2014/6/15. N2 - BACKGROUND The objectives of this study were to identify factors associated with treatment differences, characterize changes in treatment patterns over time, and compare survival across treatment types in patients who received treatment for localized laryngeal cancer. METHODS Using the Surveillance, Epidemiology, and End Results database, we conducted a retrospective cohort analysis of patients who were treated from 1995 to 2009 for localized laryngeal cancer. Four treatment groups were defined: (1) radiation only, (2) local surgery only, (3) local surgery and radiation, and (4) open surgery with or without radiation. Variations in treatment rates between these groups were evaluated according to demographic factors, and differences in treatment rates ...
Thesis, English, Potential role of Bcl 2 and Ki 67 expressions in predicting the response to radiotherapy of T1 and T2 clinical stages of laryngeal squamous cell carcinoma for Ezzo Eman Mohamed Hassan
To test whether the distribution of AHH inducibility is shifted toward the high end of the range in patients who had lung and laryngeal cancer, we measured this trait in 59 patients (32 lung and 27 laryngeal) who had resectable tumors and had been disease-free for a period of time. The advantage of selecting patients who were free of clinical disease was that measurement of their AHH inducibility should not have been affected by the disease state. Patient and control populations showed no difference in basal and induced AHH activity of AHH inducibility. The mean AHH inducibility in patients who had lung cancer was 3.20 +/- 0.20; in patients who had laryngeal cancer 2.96 +/- 0.18, and for all controls 3.29 +/- 0.04 (no significant difference at p = 0 05). Further analysis of the distribution of AHH inducibility in the patient group compared to controls showed no suggestion of a shift toward the higher end of the range in patients who had lung and laryngeal cancer.
Tumours of head and neck belong to the most frequent types of cancer world-wide. In Poland, mortality from larynx cancer among males has been continuously increasing during the last decades up to 8.4 deaths per 100,000 men in 1993, which exceeds epidemiological records from other countries. The aetiology of laryngeal cancer is strongly associated with exposure to carcinogens present in tobacco smoke. The review describes a sequence of molecular and cellular events from carcinogenic exposure, DNA adduct formation, detection of mutations in the p53 gene, loss of heterozygosity (LOH) in chromosomal loci encoding the p53 and p16 genes, and loss of control of the cell cycle. The section concerning DNA adducts includes a discussion of the role of such confounders as exogenous exposure, the age and sex of the subject, and disease progression. The significance of genetic factors as individual risk determinants is discussed in relation to bleomycin-induced chromosome instability and in connection with ...
1. Torre LA, Bray F, Siegel RL. et al. Global cancer statistics, 2012. CA Cancer J Clin. 2015;65:87-108 2. Siegel RL, Miller KD, Jemal A. Cancer Statistics, 2017. CA Cancer J Clin. 2017;67:7-30 3. Chen W, Zheng R, Baade PD. et al. Cancer statistics in China, 2015. CA Cancer J Clin. 2016;66:115-32 4. Wong TS, Gao W, Li ZH. et al. Epigenetic dysregulation in laryngeal squamous cell carcinoma. J Oncol. 2012;2012:739461 5. Shimura T, Kakuda S, Ochiai Y. et al. Targeting the AKT/GSK3beta/cyclin D1/Cdk4 survival signaling pathway for eradication of tumor radioresistance acquired by fractionated radiotherapy. Int J Radiat Oncol Biol Phys. 2011;80:540-8 6. Li Z, Yang X, Xia N. et al. PTOP and TRF1 help enhance the radio resistance in breast cancer cell. Cancer Cell Int. 2014;14:7 7. Zhou FX, Xiong J, Luo ZG. et al. cDNA expression analysis of a human radiosensitive-radioresistant cell line model identifies telomere function as a hallmark of radioresistance. Radiat Res. 2010;174:550-7 8. Kim JS, Chang ...
In conclusion, we have showed that miR-106b is one of oncogenic miRNAs in laryngeal carcinomas and RB is a novel and critical target of miR-106b. These results suggest that miR-106b might be useful as a potential therapeutic target for laryngeal carcinoma. and more in depth analysis is required. Acknowledgements This work was supported by grant which is funded Tariquidar molecular weight by Taizhou Peoples Hospital for the construction of Jiangsu province hospital clinical key subjects. References 1. Marioni G, Marchese-Ragona R, Cartei G, Marchese F, Staffieri A: Current opinion in diagnosis and treatment of laryngeal carcinoma. Cancer Treat Rev 2006, 32:504-515.PubMedCrossRef 2. Papadas TA, Alexopoulos EC, Mallis A, Jelastopulu E, Mastronikolis NS, Goumas P: Survival after laryngectomy: a review of 133 patients with laryngeal carcinoma. Eur Arch Otorhinolaryngol 2010, 267:1095-1101.PubMedCrossRef 3. Shi L, Cheng Z, Zhang J, Li R, Zhao P, Fu Z, You Y: hsa-mir-181a and hsa-mir-181b ...
Patients with larynx cancer who received a three-drug combination of docetaxel, cisplatin and 5-fluorouracil (TPF) during induction chemotherapy were more likely to retain larynx function than were patients treated with cisplatin and 5-fluoruracil (PF) alone, according to data from a randomized controlled trial in the March 24 online issue of the Journal of the National Cancer Institute.
Cu toate astea, n cele mai multe din cazuri infecia se remite de la A. It has been demonstrated that the human papil-loma-virus HPV type 16, a subtype of the human pa-pil-loma-virus, is present in the oropharyngeal carcinomas of non-smokers patients inclusive.
TY - JOUR. T1 - Pre- and post-radiotherapy MRI results as a predictive model for response in laryngeal carcinoma. AU - Ljumanovic, R.. AU - Langendijk, J.A.. AU - Hoekstra, O.S.. AU - Knol, D.L.. AU - Leemans, C.R.. AU - Castelijns, J.A.. PY - 2008. Y1 - 2008. U2 - 10.1007/s00330-008-0986-x. DO - 10.1007/s00330-008-0986-x. M3 - Article. C2 - 18491097. VL - 18. SP - 2231. EP - 2240. JO - European Radiology. JF - European Radiology. SN - 0938-7994. IS - 10. ER - ...
Laryngeal cancer represents the malignant degeneration, of epithelial nature or from the connective tissue, which starts in the constitutive elements of the larynx. Cancer localization in the larynx represents between 1% and 3% of all malignant tumors and approximately 50% of ear, nose and throat (ENT) tumors. Squamous cell carcinoma is the most common form (around 95%) of laryngeal cancer, with high incidence in human males from southern and central Europe, Romania occupying one of the top places. Material and Methods. Our study consisted of 490 patients diagnosed with laryngeal cancer from 2010 to 2016. They have been clinically, histologically, immunohistochemically, genetically, therapeutically and prognostically analyzed. Suspended microlaringoscopy has been the standard, allowing tumor extension evaluation and biopsy. All specimens were microscopically analyzed in standard or special histology stainings. For unclear histology specimens, immunohistochemical stainings were performed. Results and
Stage I larynx cancer can be treated with surgery or radiation therapy. When radiation therapy is used, surgery is reserved for cancer recurrence.
PURPOSE: Retrospective studies indicate that larger tumour volume is a strong prognostic indicator for poor tumour control after (chemo)radiotherapy for laryngeal cancer. The impact of tumour volume on the outcome of patients treated within a prospective study comparing accelerated radiotherapy (AR)+/-carbogen breathing and nicotinamide (ARCON) was investigated. METHODS AND MATERIALS: Of 345 patients with cT2-4 laryngeal cancer, pre-treatment computed tomography (CT) scans of 270 patients were available for tumour volume calculation. Contouring of the primary tumour and involved lymph nodes was reviewed by one experienced head and neck radiation oncologist. Kaplan-Meier plots were used for analysis of outcome. RESULTS: Of 137 AR and 133 ARCON patients, 57 and 80 versus 56 and 77 patients had glottic and supraglottic tumours, respectively. A correlation between primary tumour volume and T-stage was observed (Rs=.51, P,.01). In both treatment arms no correlation was detected between the primary ...
Learn about Laryngeal Cancer, a rare throat cancer that affects the larynx. Dr. Robert Contrucci of ENT Pembroke Pines treats Larynx Cancer and other throat conditions.
Radiotherapy uses high-energy rays to destroy laryngeal cancer cells. It can be given on its own or with other cancer treatments.
Alcohol and tobacco are the 2 main things that can increase your risk of developing laryngeal cancer. Theyre thought to contain chemicals that can damage the cells of the larynx.. The more you drink or smoke, the higher your risk of developing laryngeal cancer.. People who smoke more than 25 cigarettes a day, or people who have smoked for more than 40 years, have been found to be about 40 times more likely to develop laryngeal cancer than people who dont smoke.. Compared to people who dont drink, people who regularly drink large amounts of alcohol are about 3 times more likely to develop laryngeal cancer.. If you drink and smoke, your risk of laryngeal cancer increases even further. By stopping both drinking and smoking, you can significantly reduce your risk of developing the condition. Read more about preventing laryngeal cancer.. ...
Laryngeal cancer starts in the cells that line the larynx. Learn about symptoms, diagnosis, treatment and risks in our guide to laryngeal cancer.
Laryngeal neoplasms Abnormal growths in the larynx (voice box) that can be cancerous or noncancerous. Laryngeal nodules ... Laryngeal paralysis Loss of function or feeling of one or both of the vocal folds caused by injury or disease to the nerves of ... This is also known as laryngeal framework surgery. The most common technique may be to insert small blocks of custom-shaped ... Laryngoplasty Laryngeal framework surgery of a paralysed vocal cord to help strengthen the voice - a window in the thyroid ...
RASSF1A and FHIT in laryngeal squamous cell carcinomas and adjacent normal mucosa". Oral Oncol. 47 (2): 104-7. doi:10.1016/j. ... ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of ... The term 'neoplasm' is a synonym of "tumor". 'Neoplasia' denotes the process of the formation of neoplasms/tumors, the process ... "II Neoplasms". World Health Organization. Retrieved 19 June 2014.. *^ a b Abrams, Gerald. "Neoplasia I". Retrieved 23 January ...
Slaney syndrome Reardon-Wilson-Cavanagh syndrome Rectal neoplasm Rectophobia Rectosigmoid neoplasm Recurrent laryngeal ... atresia Radiation induced angiosarcoma of the breast Radiation induced meningioma Radiation leukemia Radiation related neoplasm ...
On infantile cerebral paralysis, 1886 Studies in pathological anatomy, especially in relation to laryngeal neoplasms, 1888 ...
... syndrome Laryngeal abductor paralysis mental retardation Laryngeal carcinoma Laryngeal cleft Laryngeal neoplasm Laryngeal ... isolated Lissencephaly Listeria infection Listeriosis Livedoid dermatitis Liver cirrhosis Liver neoplasms Lobar atrophy of ... pulmonary Lymphangiomyomatosis Lymphatic filariasis Lymphatic neoplasm Lymphedema distichiasis Lymphedema hereditary type 1 ... papillomatosis Laryngeal web congenital heart disease short stature Laryngocele Laryngomalacia dominant congenital ...
RASSF1A and FHIT in laryngeal squamous cell carcinomas and adjacent normal mucosa". Oral Oncol. 47 (2): 104-7. doi:10.1016/j. ... ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of ... The term "neoplasm" is a synonym of "tumor". "Neoplasia" denotes the process of the formation of neoplasms/tumors, the process ... p. Neoplasm. ISBN 978-0781733908. "II Neoplasms". International Statistical Classification of Diseases and Related Health ...
Laryngeal stroboscopy is the primary clinical tool used for this purpose. Laryngeal stroboscopy uses a synchronized flashing ... Neoplasm (Premalignant: dysplasia) - (Malignant: Squamous cell carcinoma) Trauma (Iatrogenic: surgery, intubation) - ( ... Surgeries involve myoectomies of the laryngeal muscles to reduce voice breaks, and laryngoplasties, in which laryngeal ... The most common laryngeal diagnosis among children is vocal fold nodules, a condition known to be associated with vocally ...
... ear neoplasms MeSH C04.588.443.665.481 - laryngeal neoplasms MeSH C04.588.443.665.650 - nose neoplasms MeSH C04.588.443.665. ... skull base neoplasms MeSH C04.588.149.828 - spinal neoplasms MeSH C04.588.180.260 - breast neoplasms, male MeSH C04.588.180.390 ... bile duct neoplasms MeSH C04.588. - common bile duct neoplasms MeSH C04.588.274.120.401 - gallbladder neoplasms ... femoral neoplasms MeSH C04.588.149.721 - skull neoplasms MeSH C04.588.149.721.450 - jaw neoplasms MeSH C04.588.149.721.450.583 ...
Other features of the laryngeal tissues may include[citation needed] Redness of the laryngeal tissues (acute) Dilated blood ... Spasmodic dysphonia Reflux laryngitis Chronic allergic laryngitis Neoplasm Croup: This presents with a barking cough, ... If laryngeal symptoms last for more than three weeks, a referral should be made for further examination, including direct ... 2007), this disease is often an uncommon cause of laryngeal symptoms and is frequently misdiagnosed as another voice disorder. ...
Bronchial adenomas/carcinoids Small cell lung cancer Mesothelioma Non-small cell lung cancer Pleuropulmonary blastoma Laryngeal ... Marginal zone B-cell lymphoma Mast cell leukemia Mediastinal large B cell lymphoma Multiple myeloma/plasma cell neoplasm ...
... liver neoplasms, experimental MeSH E05.598.500.496.843 - mammary neoplasms, experimental MeSH E05.598.500.496.937 - melanoma, ... laryngeal masks MeSH E05.588.465.340 - electrophoresis, microchip MeSH E05.588.570.660 - oligonucleotide array sequence ... neoplasms, experimental MeSH E05.598.500.496.500 - leukemia, experimental MeSH E05.598.500.496.750 - ...
... paranasal sinus neoplasms MeSH C08.460.669.693.575 - maxillary sinus neoplasms MeSH C08.460.692.503 - paranasal sinus neoplasms ... laryngeal MeSH C08.618.846.450 - hantavirus pulmonary syndrome MeSH C08.618.846.565 - hypoventilation MeSH C08.618.846.565.500 ... paranasal sinus neoplasms MeSH C08.785.600.693.575 - maxillary sinus neoplasms MeSH C08.785.640.700 - pleural effusion, ... mediastinal neoplasms MeSH C08.846.187.790 - mediastinitis The list continues at List of MeSH codes (C09).. ...
... and laryngeal pharynx (laryngopharynx - also referred to as the hypopharynx), from top to bottom). The pharynx is a ... unlike other head and neck primary tumours that may have associated second neoplasms, that may occur at the same time ( ...
July 2009). "Regulation of the cell cycle gene, BTG2, by miR-21 in human laryngeal carcinoma". Cell Research. 19 (7): 828-37. ... it has been demonstrated as an independent prognostic factor in patients with pancreatic neuroendocrine neoplasms. miR-21 has ... "Prognostic relevance of proliferation-related miRNAs in pancreatic neuroendocrine neoplasms". European Journal of Endocrinology ...
However, the laryngeal instrumentation involved in the intubation process is associated with a acute, brief rise in ... cerebral neoplasm. Clinical researches have recommended ICP and cerebral perfusion pressure (CPP) monitoring in any persons ...
The tumor infiltrates into infrahyoid muscles, trachea, oesophagus, recurrent laryngeal nerve, carotid sheath, etc. The tumor ... Newly reclassified variant: noninvasive follicular thyroid neoplasm with papillary-like nuclear features is considered an ... be present are pain in the anterior region of the neck and changes in voice due to an involvement of the recurrent laryngeal ...
ISBN 0-7020-2606-9. Huete-Garin, A.; S.S. Sagel (2005). "Chapter 6: "Mediastinum", Thymic Neoplasm". In J.K.T. Lee; S.S. Sagel ... Symptoms are sometimes confused with bronchitis or a strong cough because the tumour presses on the recurrent laryngeal nerve. ...
"Comprehensive expression profiling of microRNAs in laryngeal squamous cell carcinoma". Head & Neck. 35 (5): 720-8. doi:10.1002/ ... "miR-28 is a thrombopoietin receptor targeting microRNA detected in a fraction of myeloproliferative neoplasm patient platelets ...
... which may be benign neoplasms) or else a malignant neoplasm (cancer). These neoplasms are also indicated, in the diagram below ... oropharyngeal/laryngeal cancer, esophageal adenocarcinoma and esophageal squamous-cell carcinoma, gastric cancer, bile duct ... Neoplasms are mosaics of different mutant cells with both genetic and epigenetic changes that distinguish them from normal ... In this way, a population of mutant cells, called a clone, can expand in the neoplasm. Clonal expansion is the signature of ...
... attributed to intracranial neoplasm Headache attributed to increased intracranial pressure or hydrocephalus caused by neoplasm ... Trigeminal neuralgia Glossopharyngeal neuralgia Nervus intermedius neuralgia Superior laryngeal neuralgia Nasociliary neuralgia ... Headache attributed directly to neoplasm Headache attributed to carcinomatous meningitis Headache attributed to hypothalamic or ...
... neoplasm seeding MeSH C23.550.727.650.895 - neoplasms, unknown primary MeSH C23.550.727.655 - neoplasm recurrence, local MeSH ... laryngeal MeSH C23.550.393.225 - failure to thrive MeSH C23.550.393.450 - fetal growth retardation MeSH C23.550.414.300 - blood ... neoplasm metastasis MeSH C23.550.727.650.560 - lymphatic metastasis MeSH C23.550.727.650.645 - neoplasm circulating cells MeSH ... C23.550.727.670 - neoplasm regression, spontaneous MeSH C23.550.727.700 - neoplasm, residual MeSH C23.550.737.500 - retrograde ...
H19 is overexpressed in laryngeal squamous cell carcinomas that relapse as compared to those that do not relapse. In a pilot ... In contrast to most other cancers, adrenocortical neoplasms appear to have decreased expression of H19. To determine a possible ... adrenocortical neoplasms, choriocarcinomas, hepatocellular carcinomas, bladder cancers, ovarian serous epithelial cancers, head ...
... neoplasms, and cysts are skin lesions that develop from the epidermal layer of the skin. Aberrant basal cell carcinoma ... laryngeal papillomatosis) Rift Valley fever Roseola infantum (exanthem subitum, exanthema subitum, sixth disease) Roseola ... an overview with emphasis on the myeloid neoplasms". Chem. Biol. Interact. 184 (1-2): 16-20. doi:10.1016/j.cbi.2009.10.009. ... neoplasms invading or aberrantly present in the dermis. Acquired progressive lymphangioma (benign lymphangioendothelioma) Acral ...
The gland receives parasympathetic nerve supply from the superior laryngeal nerve and the recurrent laryngeal nerve. There are ... The most common neoplasm affecting the thyroid gland is a benign adenoma, usually presenting as a painless mass in the neck. ... A small horn at the back of the thyroid lobes, usually close to the recurrent laryngeal nerve and the inferior thyroid artery, ... In this region, the recurrent laryngeal nerve and the inferior thyroid artery pass next to or in the ligament. Typically, four ...
cystic neoplasms: Serous microcystic adenoma. *Intraductal papillary mucinous neoplasm. *Mucinous cystic neoplasm ...
Salivary gland neoplasm. *Sarcoma. *Skin cancer. *Small intestine cancer. *Small-cell carcinoma ...
Thus, a clone with a mutation in a tumor suppressor gene or oncogene will expand only in a neoplasm if that mutation gives the ... RASSF1A and FHIT in laryngeal squamous cell carcinomas and adjacent normal mucosa". Oral Oncology. 47 (2): 104-7. doi:10.1016/j ... Some of the small polyps in the field defect shown in the photo of the opened colon segment may be relatively benign neoplasms ... These neoplasms are also indicated (in the diagram below the photo) by 4 small tan circles (polyps) and a larger red area ( ...
Horn, L; Lovly, CM; Johnson, DH (2015). "Chapter 107: Neoplasms of the lung". In Kasper, DL; Hauser, SL; Jameson, JL; Fauci, AS ... Invasion of the mediastinum, heart, great vessels, trachea, carina, recurrent laryngeal nerve, esophagus, or vertebra. ... "Immunohistochemistry for Assessment of Pulmonary and Pleural Neoplasms: A Review and Update". Int J Clin Exp Pathol. 1 (1): 19 ...
Laryngeal polyps[edit]. Polyps on the vocal folds can take on many different forms, and can sometimes result from vocal abuse, ... Some polyps are tumors (neoplasms) and others are nonneoplastic (for example, hyperplastic or dysplastic). The neoplastic ones ...
Large cell lung carcinoma (LCLC) is a heterogeneous group of undifferentiated malignant neoplasms originating from transformed ... in that the tumor cells lack light microscopic characteristics that would classify the neoplasm as a small-cell carcinoma, ...
Laryngeal abductor paralysis mental retardation. *Laryngeal web congenital heart disease short stature ... Lymph node neoplasm. *Lymphadenopathy, angioimmunoblastic with dysproteinemia. *Lymphangiectasies lymphoedema type Hennekam ...
Tseng-Tong Kuo, Classification of thymic epithelial neoplasms: a controversial issue coming to an end?, J.Cell.Mol.Med. 5. ... Fujita A, Nakazato Y, Tachibana K, Goya T., Thymic metastasis of laryngeal cancer. Kyobu Geka. september 2011;64(10):912-5., ... Using the World Health Organization Classification of Thymic Epithelial Neoplasms to Describe CT Findings, AJR:179, oktoober ...
Lung cancer is an extremely heterogeneous family of malignant neoplasms,[1] with well over 50 different histological variants ...
The gland receives parasympathetic nerve supply from the superior laryngeal nerve and the recurrent laryngeal nerve.[4] ... The most common neoplasm affecting the thyroid gland is a benign adenoma, usually presenting as a painless mass in the neck.[64 ... The trachea, larynx, lower pharynx and esophagus all lie behind the thyroid.[5] In this region, the recurrent laryngeal nerve[8 ... usually close to the recurrent laryngeal nerve and the inferior thyroid artery, is called Zuckerkandl's tubercle.[9] ...
Salivary gland neoplasms *Benign: Basal cell adenoma. *Canalicular adenoma. *Ductal papilloma. *Monomorphic adenoma ... Laryngeal papillomatosis. *Butcher's wart. *Bowenoid papulosis. *Epidermodysplasia verruciformis. *Verruca plana. *Pigmented ...
Salivary gland neoplasms *Benign: Basal cell adenoma. *Canalicular adenoma. *Ductal papilloma. *Monomorphic adenoma ... Laryngeal papillomatosis. *Butcher's wart. *Bowenoid papulosis. *Epidermodysplasia verruciformis. *Verruca plana. *Pigmented ...
Recurrent laryngeal nerve, Thrombophilia (T, good article since 29 March 2011), Vancomycin-resistant Staphylococcus aureus, ... Myeloproliferative neoplasm, Non-alcoholic fatty liver disease, Pericarditis, Paraneoplastic syndrome, Paroxysmal nocturnal ...
Glandular and epithelial neoplasms (ICD-O 8010-8589). Epithelium. Papilloma/carcinoma. (8010-8139). *Small cell carcinoma ...
Laryngeal cyst. Laryngitis. Laryngopharyngeal reflux (LPR). Laryngospasm. vocal folds. Laryngopharyngeal reflux (LPR). Vocal ... Necrotizing tumors: 8% to 18% are due to neoplasms across all age groups, higher in older people; primary squamous carcinoma of ...
... recurrent laryngeal inflammation may result in laryngomalacia or permanent laryngeal stenosis with inspiratory dyspnea that may ... Myelodysplasia,[5] Myeloproliferative neoplasm.[5][15] Dermatologic diseases. Psoriasis,[5] atopic dermatitis,[5] lichen ruber ... Inflammation occurs in the laryngeal, tracheal and bronchial cartilages.[4] Both of these sites are involved in 10% of persons ... Tracheobronchial involvement may or may not be accompanied with laryngeal chondritis and is potentially the most severe ...
Laryngeal prominence - The Adam's apple, or laryngeal prominence, colloquially known as the neck triangle, is the lump or ... Papillary - In oncology, papillary refers to neoplasms with projections ("papillae", from Latin, 'nipple') that have ... Laryngeal ventricle - (also called the ventricle of the larynx, laryngeal sinus, or Morgagni's sinus) is a fusiform fossa, ... Medical Definition of Laryngeal sinus in Updated 05 Mar 2000 Elias, H.; Bengelsdorf, H. (1 July 1952). "The Structure ...
... , Laryngeal Tumor, Vocal Cord Cancer, Squamous Cell Carcinoma of the Larynx, Laryngeal Cancer, Laryngeal ... Laryngeal Neoplasms, Neoplasm, Laryngeal, Neoplasms, Laryngeal, larynx neoplasm, LARYNGEAL NEOPL, NEOPL LARYNGEAL, LARYNX NEOPL ... Laryngeal neoplasia, Laryngeal neoplasm NOS, Neoplasm larynx, Larynx Neoplasms, Neoplasm, Larynx, Neoplasms, Larynx, Laryngeal ... Laryngeal Neoplasm. Laryngeal Neoplasm Aka: Laryngeal Neoplasm, Laryngeal Tumor, Vocal Cord Cancer, Squamous Cell Carcinoma of ...
The goal of this study is to report a successful case of a laryngeal neoplasm removal through endoscopy. A head and neck ... Image taken after the excision of the neoplasm; the clearing of the laryngeal lumen; D. Dissection of the neoplasm, displaying ... there are few reports in the veterinary literature of such neoplasms in dogs. The laryngeal neoplasms reported in dogs were ... Image taken after the excision of the neoplasm; the clearing of the laryngeal lumen; D. Dissection of the neoplasm, displaying ...
"Laryngeal Neoplasms" by people in this website by year, and whether "Laryngeal Neoplasms" was a major or minor topic of these ... "Laryngeal Neoplasms" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Below are the most recent publications written about "Laryngeal Neoplasms" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Laryngeal Neoplasms". ...
ICD-10-CM Neoplasms Index References for C32.3 - Malignant neoplasm of laryngeal cartilage The ICD-10-CM Neoplasms Index ... Malignant neoplasm of laryngeal cartilage BILLABLE Billable Code Billable codes are sufficient justification for admission to ... C32.3 is a billable ICD code used to specify a diagnosis of malignant neoplasm of laryngeal cartilage. A billable code is ... The ICD code C32 is used to code Respiratory tract neoplasm A respiratory tract neoplasm is a tumor that affects a portion of ...
Otorhinolaryngologic Neoplasms. Head and Neck Neoplasms. Neoplasms by Site. Neoplasms. Laryngeal Diseases. Respiratory Tract ... Recurrence laryngeal cancer Other: Recurrence laryngeal cancer Recurrence laryngeal cancer has a wide range of invasion, rapid ... No recurrence laryngeal cancer Other: Recurrence laryngeal cancer Recurrence laryngeal cancer has a wide range of invasion, ... Trial record 10 of 31 for: Recruiting, Not yet recruiting, Available Studies , Laryngeal Neoplasms ...
Laryngeal Neoplasms. Otorhinolaryngologic Neoplasms. Head and Neck Neoplasms. Neoplasms by Site. Neoplasms. Laryngeal Diseases ... Investigation of Contralateral Arytenoid Sparing IMRT for T1a & T2a Larynx Cancer & Analysis of Post-treatment Laryngeal ... of Contralateral Arytenoid Sparing IMRT for T1a and T2a Larynx Cancer With Detailed Analysis of Post-treatment Laryngeal ...
Tibbetts KM, Tan M. Role of Advanced Laryngeal Imaging in Glottic Cancer: Early Detection and Evaluation of Glottic Neoplasms. ... Role of Advanced Laryngeal Imaging in Glottic Cancer : Early Detection and Evaluation of Glottic Neoplasms. In: Otolaryngologic ... Role of Advanced Laryngeal Imaging in Glottic Cancer : Early Detection and Evaluation of Glottic Neoplasms. / Tibbetts, ... Early identification of laryngeal neoplasms results in improved prognosis and functional outcomes. Imaging plays an integral ...
Laryngeal Neoplasms, Male, Middle Aged, Prognosis, Tumor Suppressor Protein p53",. author = "Halmos, {Gyorgy B} and {van der ... Is human papillomavirus involved in laryngeal neuroendocrine carcinoma?. Halmos, G. B., van der Laan, T. P., van Hemel, B. M., ... Is human papillomavirus involved in laryngeal neuroendocrine carcinoma? / Halmos, Gyorgy B; van der Laan, Tom P; van Hemel, ... All cases were negative for the low-risk HPV types HPV6 and HPV11 that are associated with laryngeal papillomatosis. High-risk ...
... and vibration patterns of the laryngeal recordings which are taken with m... ... Laryngeal Neoplasms. Cancers or tumors of the LARYNX or any of its parts: the GLOTTIS; EPIGLOTTIS; LARYNGEAL CARTILAGES; ... Laryngeal cancer is at risk of recurrence.... Feasibility of Laryngeal Mask Airway Gastro on Patients Undergoing Endoscopic ... Laryngeal Disorders and GERD in Assiut University. Study laryngeal disorders by laryngoscopic examination by two physicians on ...
These preliminary results suggest a new role for chemotherapy in patients with advanced laryngeal cancer and indicate that a ... Laryngeal Neoplasms / radiotherapy * Laryngeal Neoplasms / therapy* * Laryngectomy * Male * Middle Aged * Neoplasm Recurrence, ... Department of Veterans Affairs Laryngeal Cancer Study Group; Gregory T Wolf, Susan Gross Fisher, Waun Ki Hong, Robert Hillman, ... Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer N Engl J ...
Laryngeal epithelial neuroendocrine neoplasms are all malignant lesions. The major categories of LNECs are typical carcinoid, ... LNECs account for approximately 1% of all laryngeal neoplasms [4]. The different subtypes show a variety of different natural ... Laryngeal Neuroendocrine Carcinomas: A Retrospective Study of 14 Cases. Yingying Zhu,1 Liming Gao,1 Yunxiao Meng,2 Wenwen Diao, ... A. Ferlito, C. E. Silver, C. R. Bradford, and A. Rinaldo, "Neuroendocrine neoplasms of the larynx: an overview," Head and Neck ...
The purpose of this study is to see what dose of the drug cidofovir is safe to treat laryngeal papillomatosis (warts in the ... Laryngeal Neoplasms. .map{width:100%;height:300px;margin-bottom:15px}. Name. Location. ... Has active laryngeal papillomatosis (warts in the throat) that requires 8 or more. surgeries per year.. - Developed this ... A Phase I/II Evaluation of Cidofovir Therapy For Recurrent Laryngeal Papillomatosis in Children. Trial Phase:. Phase 1. Minimum ...
The purpose of this study is to investigate the relationship between SDF-1/CXCR4 and metastasis of laryngeal and hypopharyngeal ... Laryngeal Neoplasms. *Carcinoma, Squamous Cell. *Neoplasm Metastasis. *Hypopharyngeal Neoplasms. .map{width:100%;height:300px; ... And such studies are limited in laryngeal and hypopharyngeal cancer.. Metastasis of laryngeal and hypopharyngeal cancer occurs ... If laryngeal and hypopharyngeal SCC that. express high levels of CXCR4 show a consistently higher incidence of lymphatic and ... Hypopharyngeal Neoplasms (National Institutes of Health) * Laryngeal Neoplasms ( ... Nasopharyngeal Neoplasms (National Institutes of Health) * Oropharyngeal Neoplasms ( ... General Information about Laryngeal Cancer (National Cancer Institute) Also in Spanish * General Information about ... Whats New in Laryngeal and Hypopharyngeal Cancer Research and Treatment? (American Cancer Society) Also in Spanish ...
Neoplasms by Histologic Type. Neoplasms. Neoplasms, Squamous Cell. Neoplasms by Site. Otorhinolaryngologic Neoplasms. Laryngeal ... Laryngeal Neoplasms. Mouth Neoplasms. Oropharyngeal Neoplasms. Neoplasms, Glandular and Epithelial. ... Respiratory Tract Neoplasms. Otorhinolaryngologic Diseases. Mouth Diseases. Stomatognathic Diseases. Pharyngeal Neoplasms. ... Head and Neck Cancer Squamous Cell Carcinoma Oral Cavity Cancer Oropharynx Cancer Hypopharynx Cancer Larynx Cancer Laryngeal ...
Laryngeal Neoplasms. *Head and Neck Neoplasms. Intervention ICMJE Drug: 18F-Fluorothymidine PET scan 18F-Fluorothymidine (0.04 ...
Laryngeal Neoplasms / epidemiology*, pathology*, surgery. Lipoma / pathology*, surgery. Lipomatosis / epidemiology*. Male. ... To the best of our knowledge, this is only the second case of laryngeal lipoma associated with lipomatosis to be reported in ... 20155698 - Laryngeal lipoma associated with diffuse lipomatosis: case report and literature review.. ... We report a case of a laryngeal lipoma that was associated with diffuse systemic lipomatosis. The tumor was successfully ...
... of all laryngeal neoplasms. The aim of this study was to report the experience of our department in the management of these ... Laryngeal Neoplasms / diagnosis, pathology*, therapy. Lymphoma, B-Cell, Marginal Zone / diagnosis, pathology*, therapy. ... BACKGROUND: Extranodal lymphomas limited to the larynx are rare, accounting for less than 1% of all laryngeal neoplasms. The ... CONCLUSIONS: Primary laryngeal lymphoma is a rare entity. Early symptoms are subtle and nonspecific, and confirmation of the ...
... expression was evaluated in 103 primary laryngeal tumors and in 42 normal laryngeal tissue specimens. Significantly higher EGFR ... Epidermal-growth-factor-receptor(EGFR) expression was evaluated in 103 primary laryngeal tumors and in 42 normal laryngeal ... Data reported here suggest that high EGFR levels may identify a sub-set of laryngeal-cancer patients with a particularly ... Laryngeal Neoplasms / chemistry* * Laryngeal Neoplasms / pathology* * Male * Middle Aged * Prognosis * Prospective Studies ...
The Role of Human Papillomavirus Infection in Etiology and Pathogenesis of Laryngeal and Esophageal Epithelial Neoplasms. ... laryngeal naoplasms-etiology, esophageal naoplasms-etiology, papillomavirus human Cite as:. Med Razgl. 1995; 34: 51-78. ... purpose of the present review is to summarize the present knowledge of human papillomavirus infection and epithelial neoplasms ...
Neoplasm , Flow Cytometry , Glycoproteins , Humans , Laryngeal Neoplasms , Therapeutics , Neoplastic Stem Cells , Radiation ... Neoplasms stem cells play an important role in resistance of laryngeal squamous cancer to chemoradiotherapy / 临床耳鼻咽喉头颈外科杂志 ... Neoplasms stem cells play an important role in resistance of laryngeal squamous cancer to ... [email protected]#To determine an approach enriching cancer stem cells from laryngeal cancer cell line. To investigate whether ...
Palabras clave : Laryngeal neoplasms; laryngectomy; organ sparing treatments; neoplasm invasiveness. · resumen en Español · ... YANEZ M, Ricardo; LOYOLA B, Francisco Javier; URZUA E, Camilo y CORNEJO F, Jorge. Total laryngectomy in advanced laryngeal ... Background: In Chile a significant number of patients is presented with advanced laryngeal cancer at diagnosis with poor ... Aim: To present the results obtained with the extended total laryngectomy in patients with advanced laryngeal carcinoma. ...
Key words Laryngeal neoplasms Malignant ¶histiocytoma Radiotherapy Received: 8 December 1998 / Accepted: 12 April 1999 ... The neoplasm was characterized by spindle-shaped atypical cells arranged in a diffuse storiform pattern. Mitoses were prominent ...
Submucosal Neoplasms of the Laryngeal Introitus. Journal of Laryngology & Otology. 2012 126(7):706-13 ... Methods for minimizing laser thermal damage associated with laryngeal surgery. *Aortic homograft reconstruction of laryngeal ... Office-based laryngeal laser surgery with the 532-nm pulsed-potassium-titanyl-phosphate laser.Curr Opin Otolaryngol Head Neck ... Fiber-based, laryngeal laser procedures for treatment of papillomatosis, premalignant/dysplasia, cancer, and vascular trauma: * ...
Malignant neoplasm of laryngeal cartilage. 2016 2017 2018 Billable/Specific Code C32.3. ... C50 Malignant neoplasm of breast* C50.0 Malignant neoplasm of nipple and areola* C50.01 Malignant neoplasm of nipple and areola ... C50.1 Malignant neoplasm of central portion of brea...* C50.11 Malignant neoplasm of central portion of brea...* C50.111 ... C50.2 Malignant neoplasm of upper-inner quadrant of...* C50.21 Malignant neoplasm of upper-inner quadrant of...* C50.211 ...
Otolaryngology - Laryngeal Disease Pages Acute Laryngitis Chronic Laryngitis Dysphonia Plicae Ventricularis Functional Aphonia ... Laryngeal Fracture Reflux Laryngitis Smokers Laryngitis Spastic Dysphonia Vocal Cord Dysfunction Vocal Cord Paralysis Vocal ... Laryngeal Disease Chapter Lip Disorders Chapter Mental Health Chapter Nasal Disease Chapter Neonatology Chapter Neurology ...
Laryngeal neoplasm. Laryngectomy. Depression. Voice.. RESUMO. OBJETIVO: O tratamento cirúrgico para o câncer de cabeça e ... Long-term quality of life after treatment of laryngeal cancer. Arch Otolaryngol Head Neck Surg 1998;124:964-71. [ Links ]. 23. ... In spite of this, the changes observed in the total group of patients who had undergone laryngeal surgery are similar, and the ... Longitudinal assessment of quality of life in laryngeal cancer patients. Head Neck 1996; 18:1-9. [ Links ]. 11. Bjordal K, ...
Laryngeal Diseases: Pathological processes involving any part of the LARYNX which coordinates many functions such as voice ... Laryngeal Neoplasms (Laryngeal Cancer) 4. Wounds and Injuries (Trauma) 5. Neoplasms (Cancer) ... Larynx Diseases; Disease, Laryngeal; Disease, Larynx; Diseases, Laryngeal; Diseases, Larynx; Laryngeal Disease; Laryngeal ... Laryngeal Diseases. Subscribe to New Research on Laryngeal Diseases Pathological processes involving any part of the LARYNX ...
Diseases associated with BCL2L12 include Autoimmune Lymphoproliferative Syndrome, Type Iii and Laryngeal Benign Neoplasm. Among ...
... representing the tenth most common malign neoplasm for males. In São Paulo City, 169 new cases of laryngeal cancer were ... to investigate occupational risk factors for laryngeal cancer. The study included 122 laryngeal cancers and 187 controls, ... Laryngeal cancer was associated with exposure to respirable free crystalline silica (OR 1,83, 95% CI 1,00 - 3,36), soot (from ... Laryngeal cancer comprises 3,1% of the new cases of cancer in men in the world, ...
  • Laryngeal cancer accounts for approximately 2.4% of new malignancies worldwide each year. (
  • Imaging plays an integral role in the diagnosis, staging, and long-term follow-up of laryngeal cancer. (
  • Tibbetts, KM & Tan, M 2015, ' Role of Advanced Laryngeal Imaging in Glottic Cancer: Early Detection and Evaluation of Glottic Neoplasms ', Otolaryngologic Clinics of North America , vol. 48, no. 4, pp. 565-584. (
  • Mortality is high in this cohort: laryngeal cancer affects over 13 000 patients in the United States, with over 3500 deaths annually.The results of the Veterans Affairs Cooperative Studies Program Laryngeal Cancer Trial and subsequent studies demonstrated similar overall survival (OS) rates for organ preservation protocols involving radiotherapy (RT) or chemoradiotherapy (CRT) when compared to surgery, with the benefit of preserving the larynx in a large majority of patients. (
  • Recurrence laryngeal cancer has a wide range of invasion, rapid progression and poor prognosis. (
  • The relationship between gastroesophageal reflux disease (GERD) and laryngeal cancer has not been fully elucidated. (
  • Rates of GERD among cases of laryngeal cancer identified in the Veterans Health Administration outpatient care files (year 2000-2006) were compared with controls. (
  • In this population, there was no increased risk of laryngeal cancer among patients with GERD. (
  • Reverse causality must be considered in future studies assessing the relationship between reflux and laryngeal cancer to limit misclassification bias. (
  • Despite the fact that laryngeal cancer causes symptoms early, the patients often present with advanced disease. (
  • Assessment of HPV 16, HPV 18, p16 expression in advanced stage laryngeal cancer patients and prognostic significance. (
  • Early laryngeal cancer can be treatment by laser surgery or radiotherapy, intermediate and advanced laryngeal carcinoma mainly surgical treatment. (
  • Laryngeal cancer is at risk of recurrence. (
  • These preliminary results suggest a new role for chemotherapy in patients with advanced laryngeal cancer and indicate that a treatment strategy involving induction chemotherapy and definitive radiation therapy can be effective in preserving the larynx in a high percentage of patients, without compromising overall survival. (
  • What Happens After Treatment for Laryngeal and Hypopharyngeal Cancer? (
  • What's New in Laryngeal and Hypopharyngeal Cancer Research and Treatment? (
  • [email protected]#To determine an approach enriching cancer stem cells from laryngeal cancer cell line . (
  • To investigate whether laryngeal cancer stem cells in chemoradiotherapy have the characteristic of resistance. (
  • In Chile a significant number of patients is presented with advanced laryngeal cancer at diagnosis with poor prognosis and less than 50% survival at 5 years. (
  • The surgical treatment of head and neck cancer, primarily laryngeal cancer, causes sequelae and can change the patient's quality of life. (
  • Laryngeal cancer comprises 3,1% of the new cases of cancer in men in the world, representing the tenth most common malign neoplasm for males. (
  • In São Paulo City, 169 new cases of laryngeal cancer were reported in 1970, representing 25,5/100.000 and 299 cases in 1985, increasing the rate to 37,6/100.000 (both for males, age standardized truncated rate, 30-74 years). (
  • The best established risk factors for laryngeal cancer are tobacco and alcohol. (
  • However, asbestos, pesticides, paints, gasoline and diesel engine emissions, dusts, among other factors are reported in the literature as occupational agents that increase the risk of laryngeal cancer. (
  • A hospital-based case-control study was conducted, in seven hospitals in São Paulo, to investigate occupational risk factors for laryngeal cancer. (
  • This study showed that occupational exposures to: respirable free crystalline silica, soot (from coal, coke, fuel oil, wood), fumes and live animals are risk factors for laryngeal cancer. (
  • Human vaccines are intended to reduce the incidence of UTERINE CERVICAL NEOPLASMS, so they are sometimes considered a type of CANCER VACCINES. (
  • The first documented case of laryngeal cancer in a child was reported by Rehn in 1868 in a 3 year-old child. (
  • What separates laryngeal cancer in children from that of adults is the timing of presentation. (
  • Laryngeal cancer is the second most common cancer among respiratory system tumors. (
  • According to a report by the American Cancer Society, 13,360 new laryngeal cancers and 3,660 new deaths were projected to occur in the USA in 2017 [ 1 ]. (
  • Laryngeal squamous cell carcinoma (LSCC) is the most common pathological type of laryngeal cancer [ 2 ]. (
  • In China, there has been an increasing incidence of laryngeal cancer in the younger population, especially in the northern region of China [ 3 ]. (
  • Metastatic laryngeal cancer to the small bowel is extremely rare. (
  • We are reporting a case of an elderly man known to have laryngeal cancer who presented with small bowel obstruction due to metastatic deposit to the small bowel. (
  • A review of the natural history of advanced laryngeal cancer, common and uncommon sites of metastasis, and the rare presentation as small bowel obstruction is illustrated in this review. (
  • The following case illustrates the successful treatment of the rare metastatic laryngeal cancer to the small bowel using laparoscopic assisted techniques. (
  • An 82-year-old Emirati male was diagnosed to have laryngeal cancer in 2007. (
  • The results suggested hypermethylation of 12 CpG sites of the promoter in both laryngeal cancer tissues and the laryngeal cancer line Hep-2 cell. (
  • There was no increase in mortality from laryngeal cancer (SMR 1.09) or neoplasms other than those listed. (
  • Objective: Total laryngectomy is a well-established treatment for locally advanced laryngeal cancer. (
  • This study aimed to determine whether total laryngectomy alone is adequate therapy for certain patient subgroups with locally advanced laryngeal cancer. (
  • Design: We performed a retrospective survival analysis of patients in the surveillance epidemiology and end results (SEER) database with locally advanced laryngeal cancer between 2004 and 2012. (
  • Conclusion: Locally advanced laryngeal cancer patients with T3 primaries, no nodal disease or primaries of the glottis may not benefit from post-operative radiotherapy when treated with primary total laryngectomy. (
  • Cervenka, BP , Rao, S , Farwell, DG & Bewley, A 2017, ' Efficacy of laryngectomy alone for treatment of locally advanced laryngeal cancer: A stage- and subsite-specific survival analysis ', Clinical Otolaryngology . (
  • A neoplasm can be benign , potentially malignant, or malignant ( cancer ). (
  • Malignant neoplasms are commonly called cancer. (
  • Secondary neoplasm refers to any of a class of cancerous tumor that is either a metastatic offshoot of a primary tumor, or an apparently unrelated tumor that increases in frequency following certain cancer treatments such as chemotherapy or radiotherapy . (
  • Laryngeal granuloma occurring after surgery for laryngeal cancer treated by surgical removal and immediate post-operative radiotherapy: A case report. (
  • Laryngeal granulomas are benign lesion that rarely occurs after surgery of laryngeal cancer. (
  • The patient was diagnosed with laryngeal granuloma 1 month after the surgery of laryngeal cancer. (
  • The patient was followed up for 3 years after surgery and the laryngeal granuloma and laryngeal cancer did not recur during follow-up. (
  • Early laryngeal cancer can usually be managed successfully with either radiotherapy or surgery. (
  • Background The primary goal of treatment in advanced laryngeal cancer is to achieve optimal oncologic outcomes while preserving function and quality of life. (
  • Its overexpression is associated with increased tumor grade and proliferation in prostate cancer and other neoplasms, including breast, ovarian, nasopharyngeal, squamous laryngeal, hepatocellular and urothelial carcinomas. (
  • Objective: To provide information on the effects of alcohol and tobacco on laryngeal cancer and its subsites. (
  • Conclusions: Our study shows that both cigarette smoking and alcohol drinking are independent risk factors for laryngeal cancer. (
  • Altered microRNAs (miRNAs) expression has been found in many cancer types, including laryngeal squamous cell carcinoma (LSCC). (
  • Does vocal cord fixation preclude nonsurgical management of laryngeal cancer? (
  • Fingerprint Dive into the research topics of 'Does vocal cord fixation preclude nonsurgical management of laryngeal cancer? (
  • Adelstein, David J. / Does vocal cord fixation preclude nonsurgical management of laryngeal cancer? . (
  • Other factors that seem to play a non-marginal role in the development of laryngeal cancer are a diet low in vitamins A and E, gastro-oesophageal reflux disease that chronically expose throat to acidic gastric juices from the stomach, and infection by human papillomavirus (HPV). (
  • Laryngeal malignant tumors represent 2% of all cancer tumors. (
  • An HPV16 independent association was observed for HPV18 and oropharyngeal cancer (OR = 8.14, 95% CI = 2.21 to 29.99 for HPV18 E6 seropositivity) and HPV6 and laryngeal cancer (OR = 3.25, 95% CI = 1.46 to 7.24 for HPV6 E7 seropositivity). (
  • These results also support a marginal role for HPV18 in oropharyngeal cancer and HPV6 in laryngeal cancer. (
  • The most appropriate treatment for laryngeal tumors is the resection of the submucosa or a partial laryngectomy however, partial and total laryngectomies are associated with many postoperative complications. (
  • Herein,we examine a cohort of patients with recurrent or persistent laryngeal SCC after definitive RT/CRT who has undergone total laryngectomy in order to identify potential preoperative predictors of clinical outcomes. (
  • We performed a prospective, randomized study in patients with previously untreated advanced (Stage III or IV) laryngeal squamous carcinoma to compare the results of induction chemotherapy followed by definitive radiation therapy with those of conventional laryngectomy and postoperative radiation. (
  • To present the results obtained with the extended total laryngectomy in patients with advanced laryngeal carcinoma. (
  • Retrospective analysis of all patients with advanced laryngeal carcinoma T4a underwent total extended laryngectomy at our center between 2007-2010. (
  • In the serie, extended total laryngectomy is a good therapeutic alternative in patients with advanced laryngeal carcinoma, with low surgical morbidity, short hospital stay and favorable survival. (
  • Patients and Methods: 37 patients with proved laryngeal or hypopharyngeal neoplasm that were candidates for total laryngectomy were included in this study. (
  • However, many advanced stage laryngeal carcinomas are treated with radiotherapy with or without chemotherapy, and surgery is used as a salvage therapy in recurrent cases [ 7 ]. (
  • RT within 24 hours after operation can significantly reduce the recurrence of laryngeal granuloma. (
  • Laryngeal epithelial neuroendocrine neoplasms are all malignant lesions. (
  • The reflex is abolished by damage to the adductory component of the recurrent laryngeal nerve, by lesions in the spinal cord in the anterior thoracic region and by excitement. (
  • can result from lesions of the vagus or recurrent laryngeal nerves, and may be acquired or congenital. (
  • These include: lasers for laryngeal lesions (that do not require general anesthesia), digital stroboscopy, transnasal esophagoscopy, pulse dye laser treatment, objective swallowing measures, and assessment and laryngeal electromyography. (
  • For lymphoid neoplasms, e.g. lymphoma and leukemia , clonality is proven by the amplification of a single rearrangement of their immunoglobulin gene (for B cell lesions) or T cell receptor gene (for T cell lesions). (
  • Aberrant expression of minichromosome maintenance protein-2 and Ki67 in laryngeal squamous epithelial lesions. (
  • Expression patterns were compared using double labelling confocal microscopy.Minichromosome maintenance protein-2 staining may increase the objectivity and reliability of histological grading of laryngeal epithelial lesions.Laryngeal brushings, combined with immuno-enhanced liquid-based cytology, could be useful, as a less invasive approach, to the detection of laryngeal malignant and premalignant lesions. (
  • Histological classification of laryngeal epithelial lesions is highly subjective, and methods of cytological detection are not well developed. (
  • Minichromosome maintenance protein-2 staining may increase the objectivity and reliability of histological grading of laryngeal epithelial lesions. (
  • Laryngeal brushings, combined with immuno-enhanced liquid-based cytology, could be useful, as a less invasive approach, to the detection of laryngeal malignant and premalignant lesions. (
  • Laryngeal lesions often result in voice changes. (
  • Laryngeal neuroendocrine carcinomas (LNECs) are rare but are the most common nonsquamous tumors of this organ, which can be divided into 2 broad categories based on their tissue of origin: epithelial and neural. (
  • Laryngeal neuroendocrine neoplasms (NENs) are a rare group of NENs of the neck, divided into epithelial (carcinomas), and neural-type tumors (paraganglioma) ( 1 ). (
  • Although researchers have learned much from the study of this diverse group of tumors over the years, the diagnosis and treatment of salivary gland neoplasms remain complex and challenging problems for the head and neck surgeon. (
  • Salivary gland neoplasms make up 6% of all head and neck tumors. (
  • Benign neoplasms occur more frequently in women than in men, but malignant tumors are distributed equally between the sexes. (
  • Almost half of all submandibular gland neoplasms and most sublingual and minor salivary gland tumors are malignant. (
  • Laryngeal papillomatosis (LP, recurrent respiratory papillomatosis) is a rare type of respiratory papillomatosis that presents with small, wart-like, noncancerous epithelial tumors of the laryngeal mucosa. (
  • Hypopharyngeal tumors, which fare worse than laryngeal tumors, warrant investigation of more aggressive treatment. (
  • Lymph node metastasis directly affects the prognosis of patients with laryngeal and hypopharyngeal SCC. (
  • The present case is the seventh described in the literature of laryngeal NEN associated with elevated serum calcitonin levels and the first case with parathyroid metastasis, suggesting the importance of a correct differential diagnosis between MTC and calcitonin-secreting laryngeal NEN, using an integrated approach of biochemistry and advanced imaging. (
  • Advanced laryngeal squamous cell carcinoma (SCC) remains a highly morbid and fatal disease despite aggressive interventions. (
  • Squamous cell carcinoma (SCC) is the most common histopathologic type of the laryngeal and hypopharyngeal malignancies, accounting for more than 90% of cancers occurring in this region. (
  • The aim of this study was to investigate CLDN11 promoter methylation and its potential relevance to clinicopathologic features and prognosis of patients with laryngeal squamous cell carcinoma (LSCC). (
  • Because squamous-cell carcinoma accounts for almost 95% of the neoplasms in this region, the discussion will refer mainly to this histopathologic subtype. (
  • Advanced laryngeal squamous cell carcinoma usually spread via lymphatic channels to the neck and chest. (
  • Promoter hypermethylation-induced transcriptional down-regulation of the gene MYCT1 in laryngeal squamous cell carcinoma. (
  • However, the expression of S100A11 and its exact function in laryngeal squamous cell carcinoma (LSCC) have not been elucidated. (
  • Two patients with laryngeal squamous cell carcinoma, presenting with a prelaryngeal abscess, are described. (
  • Sections of normal larynx (n=10), laryngeal dysplasia (n=20) and laryngeal squamous cell carcinoma (SCC) (n=10) were classified according to the Ljubljana classification and stained for markers of cell cycle entry, minichromosome maintenance protein-2 (Mcm-2) and Ki67. (
  • Laryngeal neuroendocrine carcinomas (LNECs) are rare and highly heterogeneous which present a wide spectrum of pathological and clinical manifestations. (
  • 1967). Among the laryngeal neoplasms, epidermóide glottic carcinomas are the most frequent ones, constituting approximately 60 to 65% of cases (Hanna et al . (
  • Over the past twenty years, team members of the Mass General Center for Laryngeal Surgery & Voice Rehabilitation have designed, developed and perfected many surgical procedures now currently in use to enhance the treatment of benign and malignant laryngeal and pharyngeal disease. (
  • Background/Objective: Cartilage invasion is important in the management plan of laryngeal and hypo pharyngeal neoplasm's. (
  • 25 had laryngeal tumor and 12 had hypo pharyngeal tumor. (
  • After the age of 60 in subjects with risk factors, examination of the oral cavity and pharyngeal-laryngeal district is recommended. (
  • EVIDENCE ACQUISITION: A careful analysis of the Literature regarding the possible etiological role of the professional activity in laryngeal neoplasia has been carried out, focusing mainly on the years 1990-2017. (
  • All cases were negative for the low-risk HPV types HPV6 and HPV11 that are associated with laryngeal papillomatosis. (
  • Has active laryngeal papillomatosis (warts in the throat) that requires 8 or more surgeries per year. (
  • C32.3 is a billable ICD code used to specify a diagnosis of malignant neoplasm of laryngeal cartilage. (
  • Clinical diagnosis of voice pathologies is performed by analyzing audio, color, shape, and vibration patterns of the laryngeal recordings which are taken with medical imaging devices such as video-laryngostroboscope, direct laryngoscopy, and high-speed videoendoscopes. (
  • By this study, we reveal new opportunities and potentials of vision-based computerized solutions for evaluation, early diagnosis, and prevention of laryngeal disorders. (
  • Clinical stage of laryngeal carcinoma and lost time at the moment of diagnosis with 15-year-long interval. (
  • Mass General's Voice Center Research Laboratories are designed to develop novel technologies, biomaterials, devices, and surgical tools for advancing the diagnosis, management and treatment of laryngeal diseases and pathologies that affect voice. (
  • Laryngeal NENs with calcitonin hypersecretion and lymph node metastases represent a diagnostic and therapeutic challenge, which should be included in the differential diagnosis of medullary thyroid carcinoma (MTC). (
  • Can Laryngeal and Hypopharyngeal Cancers Be Found Early? (
  • Can Laryngeal and Hypopharyngeal Cancers Be Prevented? (
  • What Are the Key Statistics about Laryngeal and Hypopharyngeal Cancers? (
  • The study included 122 laryngeal cancers and 187 controls, selected by frequency matching on sex and age. (
  • The excess mortality from pneumoconiosis, malignant mesothelioma, and respiratory cancers, but not stomach neoplasms, was dependent on time since first exposure and cumulative exposure. (
  • [5] Malignant neoplasms are also simply known as cancers and are the focus of oncology . (
  • Laryngeal neoplasms represent 2% of all human cancers. (
  • A primary or metastatic malignant neoplasm involving the larynx. (
  • Complete small bowel obstruction secondary to metastatic laryngeal caner is rarely reported in the literature. (
  • INTRODUCTION: Cigarette smoking and alcohol abuse have always been considered the risk factors most involved in the etiology of laryngeal carcinoma. (
  • Changes in a Daily Phonotrauma Index After Laryngeal Surgery and Voice Therapy: Implications for the Role of Daily Voice Use in the Etiology and Pathophysiology of Phonotraumatic Vocal Hyperfunction. (
  • At first imaging, a laryngeal lesion with lateral cervical lymphadenopathies was found, and it resulted as a moderately differentiated neuroendocrine tumor (G2), Ki67 = 5%, positive for calcitonin. (
  • Current English, however, both medical and non-medical, uses tumor as a synonym for a neoplasm (a solid or fluid-filled cystic lesion that may or may not be formed by an abnormal growth of neoplastic cells) that appears enlarged in size. (
  • Septate hyphae were observed on histopathology of the laryngeal lesion, which was further confirmed as Aspergillus fumigatus after extraction of fungal DNA from formalin fixed paraffin embedded tissue (FFPET) and sequencing. (
  • a part of acute inflammation of the laryngeal mucosa due to infection, allergy or inhalation of irritant materials. (
  • This article highlights advanced laryngeal imaging techniques and their application to early glottic neoplasms. (
  • Inducible laryngeal obstruction: Endoscopic quantitative analysis of glottic aperture. (
  • Using a method developed for this study, the objective was to perform a quantitative analysis of glottic aperture during the respiratory cycle in subjects suspected of having inducible laryngeal obstr. (
  • [ 1 ] The incidence of salivary gland neoplasms as a whole is approximately 5.5 cases per 100,000 individuals in the United States, with malignant neoplasms accounting for 0.9 cases per 100,000. (
  • IMPORTANCE A rare variant of mucous membrane pemphigoid (MMP) is characterized by circulating anti-laminin 332 (Lam332) autoantibodies and seems to be associated with concurrent malignant neoplasms. (
  • benign neoplasms , in situ neoplasms , malignant neoplasms , and neoplasms of uncertain or unknown behavior. (
  • Potentially-malignant neoplasms include carcinoma in situ . (
  • Diseases associated with BCL2L12 include Autoimmune Lymphoproliferative Syndrome, Type Iii and Laryngeal Benign Neoplasm . (
  • It is the most important symptom of laryngeal diseases. (
  • The goal of this study is to report a successful case of a laryngeal neoplasm removal through endoscopy. (
  • We report a case of a laryngeal lipoma that was associated with diffuse systemic lipomatosis. (
  • Early identification of laryngeal neoplasms results in improved prognosis and functional outcomes. (
  • art methods and reveals open issues and problems of computing solutions for analysis and identification of laryngeal disorders. (
  • Two imaging findings were considered as neoplastic invasion of the laryngeal cartilage-increased density and chondrolysis. (
  • Study laryngeal disorders by laryngoscopic examination by two physicians on GERD patients diagnosed by gastroenterology department by endoscopy and effect of GERD treatment for 3 months on. (
  • 2 ], the larynx has received increasing attention in the potential for development of different neuroendocrine neoplasms there. (
  • Laryngeal neuroendocrine neoplasms (NENs) are a rare group of NENs of the neck, which commonly show immunostaining for calcitonin. (
  • abstract = "The purpose of this study was to detect human papillomavirus (HPV) infection in laryngeal neuroendocrine carcinoma (LNEC) and to explore the possible relationship between HPV-induced malignant transformation and prognosis in LNEC. (
  • abstract = "The case of a male child with a benign neurogenic laryngeal tumour caused by von Recklinghausen's disease is presented. (
  • The intention of this study is to compare the performance of the single-use I-gel laryngeal mask with the classic laryngeal mask in 50 patients with a BMI>25 during elective surgery. (
  • This study was conducted to determine the diagnostic accuracy of computed tomography (CT) to detect the neoplastic invasion of the laryngeal cartilages. (
  • On initial pathologic examination, the biopsy specimen contained scar and granulation tissue but was negative for a neoplasm. (
  • Primary laryngeal lymphoma: report of 3 cases and review of the literature. (
  • CONCLUSIONS: Primary laryngeal lymphoma is a rare entity. (
  • Usually for primary laryngeal granulomas, surgical treatment alone is not enough, because it is easy to relapse. (
  • Primary laryngeal aspergillosis in immunocompetent individuals is extremely rare, with a few cases documented over the last five decades. (
  • We report a case of primary localised laryngeal aspergillosis in a 21-year-old apparently immunocompetent student. (
  • Since last few decades, cases of primary laryngeal aspergillosis in immunocompetent individuals are on the rise, globally. (
  • Primary laryngeal aspergillosis in immunocompetent individuals is extremely rare. (
  • Herein, a case of primary laryngeal aspergillosis in an apparently immunocompetent young adult is reported. (
  • HPV types 16 and 18 have been well documented in cervical carcinoma in situ and invasive neoplasm of the cervix. (
  • Bar charts (median±IQR) comparing Mcm-2 LIs in different compartments of the laryngeal epithelium in normal larynx (n=8), atypical hyperplasia (n=10), carcinoma in situ (n=9). (
  • The aim of this paper was to take stock of the main occupational risk factors that could affect, independently and/or complement, on the development of laryngeal carcinoma. (
  • A head and neck radiogram revealed a mass in the laryngeal lumen protruding into the trachea. (
  • A method and devices for transcutaneous or transmucosal stimulation of the recurrent laryngeal nerve are provided. (
  • Recurrent laryngeal nerve stimulation is delivered by applying electric charge from an electrode in the form of a probe or an indwelling device to the intact neck skin at specific points. (
  • 2. A device as described in claim 1, further comprising means for generating an electrical current to the leads such that the electrodes produce an electrical stimulus, wherein the electrical stimulus has a frequency which is selected to evoke a predetermined amount of stimulation in at least one laryngeal muscle and a current effective to selectively stimulate at least a portion of the recurrent laryngeal nerve. (
  • Direct stimulation of the recurrent laryngeal nerve (RLN) results in a characteristic movement of the vocal cords that is frequency dependent. (
  • This trial determines the feasibility of Laryngeal Mask Airway Gastro (Laryngeal Mask Airway) when used on patients who are undergoing endoscopic retrograde cholangiopancreatography for pa. (
  • Laryngeal image/video analysis is discussed in four main categories: segmentation of vocal folds, classification of vocal fold disorders, vocal fold vibration analysis, and vocal fold image stitching. (
  • Microlaryngoscopy demonstrated laryngeal papillomas and a fixed right vocal cord. (
  • Objectives/Hypothesis: To determine whether vocal cord fixation precludes nonsurgical management of T3/T4 laryngeal carcinoma. (
  • The purpose of the present review is to summarize the present knowledge of human papillomavirus infection and epithelial neoplasms of the larynx and esopha-gus, and to briefly present the results of human papillomavirus studies done in Slovenia. (