Cancers or tumors of the LARYNX or any of its parts: the GLOTTIS; EPIGLOTTIS; LARYNGEAL CARTILAGES; LARYNGEAL MUSCLES; and VOCAL CORDS.

Elevation of the epidermal growth factor receptor and dependent signaling in human papillomavirus-infected laryngeal papillomas. (1/1167)

Laryngeal papillomas are benign tumors caused by human papillomaviruses types 6 and 11. This study addressed alterations in levels of signal transduction from the epidermal growth factor receptor (EGFR) in papillomas and cultured papilloma cells compared to normal tissue and cells. Mitogen-activated protein kinase (MAPK) was activated to a greater extent, phosphotyrosine was more abundant, and EGFR was overexpressed in laryngeal papillomas compared to normal laryngeal epithelium by Western blot analysis. The EGFR was 3 times more abundant in cultured papilloma cells than in normal laryngeal cells by Scatchard analysis and Western blot, without gene amplification or an increase in steady-state levels of mRNA. Following stimulation with EGF, a significant portion of the EGFR was recycled to the surface in papilloma cells, whereas in normal cells, it was not. Tyrosine kinase activity and activation of MAPK was more responsive to epidermal growth factor stimulation in papilloma cells than in uninfected primary laryngeal cells. PD153035, a specific inhibitor of the EGFR, and an EGFR-specific antibody that blocks ligand binding completely abrogated basal MAPK activation by endogenous ligands in laryngeal papilloma cells. These results demonstrated that infection of laryngeal epithelium by low-risk human papillomaviruses elevates the EGFR by posttranslational mechanisms, increasing its responsiveness to ligand-mediated activation. They also showed that MAPK activation in laryngeal papillomas depends upon ligand-mediated EGFR stimulation.  (+info)

Glutathione S-transferase GSTM3 and GSTP1 genotypes and larynx cancer risk. (2/1167)

Glutathione S-transferases (GSTs) are involved in detoxification of reactive metabolites of carcinogens and, therefore, could be potentially important in susceptibility to cancer. The associations between larynx cancer risk and GSTM3 and GSTP1 gene polymorphisms, either separately or in combination with GSTM1 and GSTT1 gene polymorphisms, were evaluated using peripheral blood DNA from 129 cancer patients and 172 controls, all regular smokers. The frequencies of GSTM3 AA, AB, and BB genotypes were 60.5%, 36.4%, and 3.1% in cases and 72.7%, 24.4%, and 2.9% in controls, respectively. The frequencies of GSTP1 AA, AG, and GG genotypes were 48.1%, 40.3%, and 11.6% in cases and 50.0%, 37.2%, and 12.8% in controls, respectively. Multivariate logistic regression analyses did not reveal any association between the GSTP1 (AG or GG) genotype and larynx cancer [odds ratio, 1.1; 95% confidence interval (CI), 0.7-2.0]. In contrast, a significant increase in risk was related to the GSTM3 (AB or BB) genotype (odds ratio, 2.0; 95% CI, 1.1-3.4). The combined GSTM3 (AB or BB) and GSTM1-null genotype conferred a 4-fold risk (95% CI, 1.6-10.1) of larynx cancer as compared with the combined GSTM3 AA and GSTM1-positive genotype. However, the effect of GSTM3 (AB or BB) genotype was similar among individuals with GSTM1-positive or GSTM1-null genotypes.  (+info)

Concordant induction of cyclin E and p21cip1 in differentiated keratinocytes by the human papillomavirus E7 protein inhibits cellular and viral DNA synthesis. (3/1167)

Productive infections by human papillomaviruses (HPVs) occur only in differentiated keratinocytes in squamous epithelia in which the HPV E7 protein reactivates the host DNA replication machinery to support viral DNA replication. In a fraction of the differentiated keratinocytes, E7 also posttranscriptionally induces p21Cip1, which is distributed in a mutually exclusive manner with unscheduled cellular DNA synthesis. In this study, double immunofluorescence labeling unexpectedly revealed that E7 caused a concordant accumulation of both cyclin E and p21Cip1 to high levels in patient papillomas and in organotypic cultures of primary human keratinocytes. The induction of cyclin E is mutually exclusive with unscheduled cellular DNA synthesis or abundant viral DNA. These novel virus-host interactions in differentiated keratinocytes are in contrast to previous observations made in submerged proliferating cultures, in which HPV E7 induces cyclin E and overcomes p21Cip1 inhibition of S-phase entry. We propose that an appropriately timed induction of cyclin E/cyclin-dependent kinase 2 by HPV E7 in postmitotic cells enables S-phase reentry and HPV DNA amplification, whereas prematurely induced cyclin E stabilizes p21Cip1 protein, which then inhibits cyclin E/cyclin-dependent kinase 2. Consequently, cyclin E and p21Cip1 both fail to turn over, and DNA synthesis does not occur.  (+info)

Preradiotherapy computed tomography as a predictor of local control in supraglottic carcinoma. (4/1167)

PURPOSE: To determine the utility of pretreatment computed tomography (CT) for predicting primary site control in patients with supraglottic squamous cell carcinoma (SCC) treated with definitive radiotherapy (RT). MATERIALS AND METHODS: Pretreatment CT studies in 63 patients were reviewed. Minimum length of follow-up was 2 years. Local recurrence and treatment complications resulting in permanent loss of laryngeal function were documented. Tumor volume was calculated using a computer digitizer, and pre-epiglottic space (PES) spread was estimated. The data were analyzed using a combination of Fisher's exact test, logistic regression modeling, and multivariate analyses. Five-year local control rates were calculated using the product-limit method. RESULTS: Local control rates were inversely and roughly linearly related to tumor volume, although there seemed to be a threshold volume at which primary site prognosis diminished. Local control was 89% in tumors less than 6 cm3 and 52% when volumes were > or =6 cm3 (P = .0012). The likelihood of maintaining laryngeal function also varied with tumor volume: 89% for tumors less than 6 cm3 and 40% for tumors > or =6 cm3 (P = .00004). Pre-epiglottic space involvement by tumor of > or =25% was associated with a reduced chance of saving the larynx (P = .0076). Multivariate analyses revealed that only tumor volume independently altered these end points. CONCLUSION: Pretreatment CT measurements of tumor volume permits stratification of patients with supraglottic SCC treated with RT alone (which allows preservation of laryngeal function) into groups in which local control is more likely and less likely. Pre-epiglottic space spread is not a contraindication to using RT as the primary treatment for supraglottic SCC.  (+info)

Sternothoracotomy for combined coronary artery bypass grafting and left upper lobectomy in a patient with low-lying tracheostoma. (5/1167)

A 64-year-old man had a low-lying tracheostoma and presented with unstable angina and a mass in the pulmonary left upper lobe. Simultaneous coronary revascularization and resection of the lung neoplasm were completed through a sternothoracotomy (clam-shell) incision. The advantages of this approach include excellent exposure to the mediastinum and the lung fields, and the option of using both internal thoracic arteries for bypass grafting.  (+info)

Suppression of extracellular signals and cell proliferation by the black tea polyphenol, theaflavin-3,3'-digallate. (6/1167)

Previous studies in our laboratory have shown that the major green tea polyphenol, (-)-epigallocatechin-3-gallate (EGCG), suppressed autophosphorylation of epidermal growth factor (EGF) receptor induced by EGF in human A431 epidermoid carcinoma cells. In this study, we examined the inhibitory effects of black tea polyphenols, including theaflavin (TF-1), a mixture (TF-2) of theaflavin-3-gallate (TF-2a) and theaflavin-3'-gallate (TF-2b), theaflavin-3,3'-digallate (TF-3) and the thearubigin fraction on the autophosphorylation of the EGF and PDGF receptors in A431 cells and mouse NIH3T3 fibroblast cells, respectively. First, we examined the effects of these polyphenols on the proliferation of A431 and NIH3T3 cells. Both EGCG and TF-3 strongly inhibited the proliferation of A431 and NIH3T3 cells more than the other theaflavins did. In cultured cells with pre-treatment of tea polyphenol, TF-3 was stronger than EGCG on the reduction of EGF receptor and PDGF receptor autophosphorylation induced by EGF and PDGF, respectively. Other theaflavins slightly reduced the autophosphorylation of the EGF and PDGF receptors; furthermore, TF-3 could reduce autophosphorylation of the EGF receptor (or PDGF receptor) even with co-treatment with EGF (or PDGF) and TF-3, but EGCG was inactive under these conditions. In addition, TF-3 was stronger than EGCG in blocking EGF binding to its receptor. These results suggest that not only the green tea polyphenol, EGCG, but also the black tea polyphenol, TF-3, have an antiproliferative activity on tumor cells, and the molecular mechanisms of antiproliferation may block the growth factor binding to its receptor and thus suppress mitogenic signal transduction.  (+info)

The difference between delayed extubation and tracheostomy in post-operative sleep apnea after glossectomy or laryngectomy. (7/1167)

BACKGROUND: Patients with cancer of the tongue or larynx require glossectomies or laryngectomies and subsequent reconstruction. These procedures remove part of the patient's upper airway. In cancer of the tongue, the removed part of the airway is substituted by a flap of their skin. Post-operatively, it is possible that the patients have problems respiring comfortably. In addition to this, long surgical procedures may simply interfere with their circadian rhythm. To elucidate the possible change in their post-operative respiration, we monitored the patient's respiratory pattern with an apnea monitor. METHODS: We attached an apnea monitor to the patients and recorded their respiratory pattern and arterial oxygen saturation. The patients were monitored for a total of five days: three days prior to the operation, one day before the operation, the day of operation, two days after, and on the fourth day after the operation. The period of monitoring was from 8:00 p.m. to 6:00 a.m. the next morning. RESULTS: Sixteen patients completed this study. The patients whose tube was extubated after glossectomy showed frequent apnea, low mean oxygen saturation and low comfort score as compared to the patients with tracheostomy after laryngectomy. Because two failed cases of free skin flap were among the former, it is possible that the frequent apnea is a factor of failed free skin graft after glossectomy and laryngectomy. CONCLUSION: Further studies are required to improve the patient's respiration during their sleep after tracheal extubation in glossectomy.  (+info)

Differential protection against benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced DNA damage in HepG2 cells stably transfected with allelic variants of pi class human glutathione S-transferase. (8/1167)

The pi class glutathione S-transferase (GSTP1-1), which is polymorphic in human populations, is believed to play an important role in detoxification of the ultimate carcinogen of widespread environmental pollutant benzo[a]pyrene [(+)-anti-benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide [(+)-anti-BPDE]]. The allelic variants of human GSTP1-1 (hGSTP1-1) differ in their structures by the amino acids in positions 104 (isoleucine or valine) and/or 113 (valine or alanine). Here, we have determined the protective effect of overexpression of allelic variants of hGSTP1-1, through stable transfection in HepG2 cells, against (+)-anti-BPDE-induced DNA modification. Clonal transfectants of HepG2 cells corresponding to the three allelic variants of hGSTP1-1 [(I104,A113), (V104,A113), and (V104,V113), denoted hGSTP1(IA), hGSTP1(VA), and hGSTP1(VV), respectively] with similar levels of hGSTP1 protein were identified and characterized for their GST activity and (+)-anti-BPDE-induced DNA modification. The glutathione S-transferase activity toward (+)-anti-BPDE was significantly higher (approximately 3.0-3.6-fold) in cells transfected with hGSTP1(VA) [HepG2(VA)] and hGSTP1(VV) [HepG2(VV)] compared with hGSTP1(IA) transfectant [HepG2(IA)]. The formation of (+)-anti-BPDE-DNA adducts was significantly reduced in HepG2(VA) and HepG2(VV) cells compared with cells transfected with insert-free vector (HepG2-vect). Maximum protection against (+)-anti-BPDE-induced DNA damage was afforded by the hGSTP1(VV) isoform. The results of this study indicate that the allelic variants of hGSTP1-1 significantly differ in their ability to provide protection against (+)-anti-BPDE-induced DNA damage. Thus, hGSTP1-1 polymorphism may be an important factor in differential susceptibility of individuals to tumorigenesis induced by benzo[a]pyrene.  (+info)

The most common types of laryngeal neoplasms include:

1. Vocal cord nodules and polyps: These are benign growths that develop on the vocal cords due to overuse, misuse, or trauma.
2. Laryngeal papillomatosis: This is a condition where warts grow on the vocal cords, often caused by the human papillomavirus (HPV).
3. Adenoid cystic carcinoma: This is a rare type of cancer that develops in the salivary glands near the larynx.
4. Squamous cell carcinoma: This is the most common type of cancer that develops in the larynx, often due to smoking or heavy alcohol consumption.
5. Verrucous carcinoma: This is a rare type of cancer that develops on the vocal cords and is often associated with chronic inflammation.
6. Lymphoma: This is a type of cancer that affects the immune system, and can develop in the larynx.
7. Melanoma: This is a rare type of cancer that develops from pigment-producing cells called melanocytes.

Symptoms of laryngeal neoplasms can include hoarseness or difficulty speaking, breathing difficulties, and ear pain. Diagnosis is typically made through a combination of physical examination, imaging tests such as CT scans or MRI, and biopsy. Treatment options vary depending on the type and severity of the neoplasm, but may include surgery, radiation therapy, or chemotherapy.

Laryngeal neoplasms Abnormal growths in the larynx (voice box) that can be cancerous or noncancerous. Laryngeal nodules ... Laryngeal paralysis Loss of function or feeling of one or both of the vocal folds caused by injury or disease to the nerves of ... This is also known as laryngeal framework surgery. The most common technique may be to insert small blocks of custom-shaped ... Laryngoplasty Laryngeal framework surgery of a paralysed vocal cord to help strengthen the voice - a window in the thyroid ...
Slaney syndrome Reardon-Wilson-Cavanagh syndrome Rectal neoplasm Rectophobia Rectosigmoid neoplasm Recurrent laryngeal ... atresia Radiation induced angiosarcoma of the breast Radiation induced meningioma Radiation leukemia Radiation related neoplasm ...
On infantile cerebral paralysis, 1886 Studies in pathological anatomy, especially in relation to laryngeal neoplasms, 1888 ...
... syndrome Laryngeal abductor paralysis mental retardation Laryngeal carcinoma Laryngeal cleft Laryngeal neoplasm Laryngeal ... isolated Lissencephaly Listeria infection Listeriosis Livedoid dermatitis Liver cirrhosis Liver neoplasms Lobar atrophy of ... pulmonary Lymphangiomyomatosis Lymphatic filariasis Lymphatic neoplasm Lymphedema distichiasis Lymphedema hereditary type 1 ... papillomatosis Laryngeal web congenital heart disease short stature Laryngocele Laryngomalacia dominant congenital ...
RASSF1A and FHIT in laryngeal squamous cell carcinomas and adjacent normal mucosa". Oral Oncol. 47 (2): 104-7. doi:10.1016/j. ... ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of ... The term neoplasm is a synonym of tumor. Neoplasia denotes the process of the formation of neoplasms/tumors, and the process is ... The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that ...
Laryngeal stroboscopy is the primary clinical tool used for this purpose. Laryngeal stroboscopy uses a synchronized flashing ... Neoplasm (Premalignant: dysplasia) - (Malignant: Squamous cell carcinoma) Trauma (Iatrogenic: surgery, intubation) - ( ... Surgeries involve myoectomies of the laryngeal muscles to reduce voice breaks, and laryngoplasties, in which laryngeal ... The most common laryngeal diagnosis among children is vocal fold nodules, a condition known to be associated with vocally ...
... ear neoplasms MeSH C04.588.443.665.481 - laryngeal neoplasms MeSH C04.588.443.665.650 - nose neoplasms MeSH C04.588.443.665. ... skull base neoplasms MeSH C04.588.149.828 - spinal neoplasms MeSH C04.588.180.260 - breast neoplasms, male MeSH C04.588.180.390 ... bile duct neoplasms MeSH C04.588.274.120.250.250 - common bile duct neoplasms MeSH C04.588.274.120.401 - gallbladder neoplasms ... femoral neoplasms MeSH C04.588.149.721 - skull neoplasms MeSH C04.588.149.721.450 - jaw neoplasms MeSH C04.588.149.721.450.583 ...
Other features of the laryngeal tissues may include[citation needed] Redness of the laryngeal tissues (acute) Dilated blood ... Spasmodic dysphonia Reflux laryngitis Chronic allergic laryngitis Neoplasm Croup: This presents with a barking cough, ... If laryngeal symptoms last for more than three weeks, a referral should be made for further examination, including direct ... 2007), this disease is often an uncommon cause of laryngeal symptoms and is frequently misdiagnosed as another voice disorder. ...
Marginal zone B-cell lymphoma Mast cell leukemia Mediastinal large B cell lymphoma Multiple myeloma/plasma cell neoplasm ... Small cell lung cancer Mesothelioma Non-small cell lung cancer Non-small cell lung carcinoma Pleuropulmonary blastoma Laryngeal ...
... liver neoplasms, experimental MeSH E05.598.500.496.843 - mammary neoplasms, experimental MeSH E05.598.500.496.937 - melanoma, ... laryngeal masks MeSH E05.588.465.340 - electrophoresis, microchip MeSH E05.588.570.660 - oligonucleotide array sequence ... neoplasms, experimental MeSH E05.598.500.496.500 - leukemia, experimental MeSH E05.598.500.496.750 - ...
... paranasal sinus neoplasms MeSH C08.460.669.693.575 - maxillary sinus neoplasms MeSH C08.460.692.503 - paranasal sinus neoplasms ... laryngeal MeSH C08.618.846.450 - hantavirus pulmonary syndrome MeSH C08.618.846.565 - hypoventilation MeSH C08.618.846.565.500 ... paranasal sinus neoplasms MeSH C08.785.600.693.575 - maxillary sinus neoplasms MeSH C08.785.640.700 - pleural effusion, ... mediastinal neoplasms MeSH C08.846.187.790 - mediastinitis The list continues at List of MeSH codes (C09). (Wikipedia articles ...
... and laryngeal pharynx (laryngopharynx - also referred to as the hypopharynx), from top to bottom). The pharynx is a ... unlike other head and neck primary tumours that may have associated second neoplasms, that may occur at the same time ( ...
July 2009). "Regulation of the cell cycle gene, BTG2, by miR-21 in human laryngeal carcinoma". Cell Research. 19 (7): 828-37. ... it has been demonstrated as an independent prognostic factor in patients with pancreatic neuroendocrine neoplasms. miR-21 has ... "Prognostic relevance of proliferation-related miRNAs in pancreatic neuroendocrine neoplasms". European Journal of Endocrinology ...
However, the laryngeal instrumentation involved in the intubation process is associated with a acute, brief rise in ... cerebral neoplasm. Clinical researches have recommended ICP and cerebral perfusion pressure (CPP) monitoring in any persons ...
The tumor infiltrates into infrahyoid muscles, trachea, oesophagus, recurrent laryngeal nerve, carotid sheath, etc. The tumor ... Newly reclassified variant: noninvasive follicular thyroid neoplasm with papillary-like nuclear features is considered an ... be present are pain in the anterior region of the neck and changes in voice due to an involvement of the recurrent laryngeal ...
Baranov E, Hornick JL (March 2020). "Soft Tissue Special Issue: Fibroblastic and Myofibroblastic Neoplasms of the Head and Neck ... difficulty in swallowing and breathing due to a laryngeal LGMS tumor, and abdominal pain due to a pancreas LGMS tumor. A study ... A Case Report and Literature Review of Laryngeal Low-Grade Myofibroblastic Sarcoma". Cureus. 12 (10): e11072. doi:10.7759/ ...
"Comprehensive expression profiling of microRNAs in laryngeal squamous cell carcinoma". Head & Neck. 35 (5): 720-8. doi:10.1002/ ... "miR-28 is a thrombopoietin receptor targeting microRNA detected in a fraction of myeloproliferative neoplasm patient platelets ...
... which may be benign neoplasms) or else a malignant neoplasm (cancer). These neoplasms are also indicated, in the diagram below ... oropharyngeal/laryngeal cancer, esophageal adenocarcinoma and esophageal squamous-cell carcinoma, gastric cancer, bile duct ... Neoplasms are mosaics of different mutant cells with both genetic and epigenetic changes that distinguish them from normal ... In this way, a population of mutant cells, called a clone, can expand in the neoplasm. Clonal expansion is the signature of ...
... attributed to intracranial neoplasm Headache attributed to increased intracranial pressure or hydrocephalus caused by neoplasm ... Trigeminal neuralgia Glossopharyngeal neuralgia Nervus intermedius neuralgia Superior laryngeal neuralgia Nasociliary neuralgia ... Headache attributed directly to neoplasm Headache attributed to carcinomatous meningitis Headache attributed to hypothalamic or ...
... neoplasm seeding MeSH C23.550.727.650.895 - neoplasms, unknown primary MeSH C23.550.727.655 - neoplasm recurrence, local MeSH ... laryngeal MeSH C23.550.393.225 - failure to thrive MeSH C23.550.393.450 - fetal growth retardation MeSH C23.550.414.300 - blood ... neoplasm metastasis MeSH C23.550.727.650.560 - lymphatic metastasis MeSH C23.550.727.650.645 - neoplasm circulating cells MeSH ... C23.550.727.670 - neoplasm regression, spontaneous MeSH C23.550.727.700 - neoplasm, residual MeSH C23.550.737.500 - retrograde ...
H19 is overexpressed in laryngeal squamous cell carcinomas that relapse as compared to those that do not relapse. In a pilot ... In contrast to most other cancers, adrenocortical neoplasms appear to have decreased expression of H19. To determine a possible ... adrenocortical neoplasms, choriocarcinomas, hepatocellular carcinomas, bladder cancers, ovarian serous epithelial cancers, head ...
However, p16 can be expressed in other neoplasms and in several normal human tissues. More than a third of urinary bladder SCCs ... laryngeal and oropharyngeal cancers. Tobacco smoking increases the carriers' susceptibility for such non-melanoma cancers. ... infection and neoplasms of cervical origin. The majority of SCCs of uterine cervix express p16. ...
... neoplasms, and cysts are skin lesions that develop from the epidermal layer of the skin. Aberrant basal cell carcinoma ... laryngeal papillomatosis) Rift Valley fever Roseola infantum (exanthem subitum, exanthema subitum, sixth disease) Roseola ... an overview with emphasis on the myeloid neoplasms". Chem. Biol. Interact. 184 (1-2): 16-20. doi:10.1016/j.cbi.2009.10.009. ... neoplasms invading or aberrantly present in the dermis. Acquired progressive lymphangioma (benign lymphangioendothelioma) Acral ...
The gland receives parasympathetic nerve supply from the superior laryngeal nerve and the recurrent laryngeal nerve. There are ... The most common neoplasm affecting the thyroid gland is a benign adenoma, usually presenting as a painless mass in the neck. ... A small horn at the back of the thyroid lobes, usually close to the recurrent laryngeal nerve and the inferior thyroid artery, ... In this region, the recurrent laryngeal nerve and the inferior thyroid artery pass next to or in the ligament. Typically, four ...
Mutant cells in neoplasms compete for space and resources. Thus, a clone with a mutation in a tumor suppressor gene or oncogene ... RASSF1A and FHIT in laryngeal squamous cell carcinomas and adjacent normal mucosa". Oral Oncology. 47 (2): 104-7. doi:10.1016/j ... Some of the small polyps in the field defect shown in the photo of the opened colon segment may be relatively benign neoplasms ... These neoplasms are also indicated (in the diagram below the photo) by 4 small tan circles (polyps) and a larger red area ( ...
Laryngeal prominence - The Adam's apple, or laryngeal prominence, colloquially known as the neck triangle, is the lump or ... Papillary - In oncology, papillary refers to neoplasms with projections ("papillae", from Latin, 'nipple') that have ... Laryngeal ventricle - (also called the ventricle of the larynx, laryngeal sinus, or Morgagni's sinus) is a fusiform fossa, ... Medical Definition of Laryngeal sinus in lexic.us. Updated 05 Mar 2000 Elias, H.; Bengelsdorf, H. (1 July 1952). "The Structure ...
See: "C16 - Malignant neoplasm of the stomach". ICD-10 Version: 2015. World Health Organization. Archived from the original on ... a result of the tumor affecting the recurrent laryngeal nerve. The presence of the tumor may disrupt the normal contractions of ...
Such mutations and epigenetic alterations can give rise to cancer (see malignant neoplasms). Germ line mutations in DNA repair ... RASSF1A and FHIT in laryngeal squamous cell carcinomas and adjacent normal mucosa". Oral Oncology. 47 (2): 104-107. doi:10.1016 ...
JavaScript is disabled for your browser. Some features of this site may not work without it ...
All MeSH CategoriesDiseases CategoryNeoplasmsNeoplasms by SiteHead and Neck NeoplasmsOtorhinolaryngologic NeoplasmsLaryngeal ... All MeSH CategoriesDiseases CategoryOtorhinolaryngologic DiseasesLaryngeal DiseasesLaryngeal Neoplasms. All MeSH Categories ... Laryngeal Neoplasms. Cancers or tumors of the LARYNX or any of its parts: the GLOTTIS; EPIGLOTTIS; LARYNGEAL CARTILAGES; ... All MeSH CategoriesDiseases CategoryRespiratory Tract DiseasesRespiratory Tract NeoplasmsLaryngeal Neoplasms ...
"Laryngeal Neoplasms" by people in this website by year, and whether "Laryngeal Neoplasms" was a major or minor topic of these ... "Laryngeal Neoplasms" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Below are the most recent publications written about "Laryngeal Neoplasms" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Laryngeal Neoplasms". ...
OR laryngeal neoplasms[mh] OR epidermodysplasia verruciformis[mh]) OR (hpv[ti] OR genital warts[ti] OR human papillomavirus[ti ... papillomavirus infections[majr:noexp] AND (genital warts[mh] OR laryngeal neoplasms[mh] OR epidermodysplasia verruciformis[mh ...
Neuroendocrine laryngeal neoplasm. A report of two cases - Otorinolaringologia 2001 December;51(4):155-8 - Minerva Medica - ... Neuroendocrine laryngeal neoplasm. A report of two cases. Saraniti C., Caramanna C., Miceli L., Dispenza C. ... Neuroendocrine -tumours are -rare and aggres-sive neo-plasms. The -most accred-it-ed hypoth-e-sis is -that -they -derive -from ... such as the laryn-geal par-a-gan-gli-o-ma, mel-a-no-ma and squa-mous car-ci-no-ma -ofthe lar-ynx for the atyp-i-cal car-ci-noid ...
Start Over You searched for: Subjects Laryngeal Neoplasms ✖Remove constraint Subjects: Laryngeal Neoplasms Publication Year ...
You are looking for all the forum topics related to Laryngeal neoplasms malignant ...
LARYNGEAL NEOPLASMS /*surg. CARCINOMA, SQUAMOUS CELL /*surg. *LARYNGECTOMY Jejunectomy. JEJUNUM /*surg. , Previous Page , 1 , 2 ... NEOPLASMS /*ther Current status of gene therapy for thyroid cancer. THYROID NEOPLASMS /*ther. *GENE THERAPY Do not routinely ... Imaging of pancreatic neoplasms. PANCREATIC NEOPLASMS /*diag image. (not DIAGNOSTIC IMAGING) Several subheadings are permitted ...
ClinicalTrials.gov: Hypopharyngeal Neoplasms (National Institutes of Health) * ClinicalTrials.gov: Laryngeal Neoplasms ( ... ClinicalTrials.gov: Nasopharyngeal Neoplasms (National Institutes of Health) * ClinicalTrials.gov: Oropharyngeal Neoplasms ( ... Childhood Laryngeal Tumors Treatment (National Cancer Institute) Also in Spanish * Childhood Nasopharyngeal Cancer Treatment ( ... General Information about Laryngeal Cancer (National Cancer Institute) Also in Spanish * General Information about ...
Laryngeal abnormalities (eg, neoplasm, polyps, cyst). * Laryngeal edema from C1INH deficiency or ACE inhibitor use ... Treatment of adductor laryngeal breathing dystonia with botulinum toxin type A. Laryngoscope. 1994 Jan. 104(1 Pt 1):30-2. [QxMD ... Table 1. Differential diagnosis of laryngeal movement disorders [69, 70, 71] (Open Table in a new window) ... Prolonged intubation, recurrent laryngeal or vagus nerve damage during chest or thyroid surgery, idiopathic. ...
Laryngeal Cancer use Laryngeal Neoplasms Laryngeal Cancers use Laryngeal Neoplasms Laryngeal Cartilage use Laryngeal Cartilages ... Laryngeal Neoplasm use Laryngeal Neoplasms Laryngeal Neoplasms Laryngeal Nerve use Laryngeal Nerves ... Laryngeal Epithelium use Laryngeal Mucosa Laryngeal Granuloma use Granuloma, Laryngeal Laryngeal Granulomas use Granuloma, ... Laryngeal Nerve Contusions use Laryngeal Nerve Injuries Laryngeal Nerve Injuries Laryngeal Nerve Injury use Laryngeal Nerve ...
2. [Laryngeal neoplasms].. Mozet C; Dietz A. Laryngorhinootologie; 2010 May; 89(5):295-315. PubMed ID: 20458662. [No Abstract ... 8. Neuroendocrine neoplasms of the larynx: an overview.. Ferlito A; Silver CE; Bradford CR; Rinaldo A. Head Neck; 2009 Dec; 31( ... Laryngeal alveolar rhabdomyosarcoma involving the true vocal fold in an adult: Case report.. Leventhal DD; Spiegel J; Keane W. ... A laryngeal cancer in pregnancy].. Matschke RG; Gräber T; Panagiotopoulos A. HNO; 1994 Aug; 42(8):505-8. PubMed ID: 7960954. [ ...
Laryngeal Neoplasms/epidemiology*; Laryngeal Neoplasms/etiology; Male; Middle Aged; Occupational Medicine*; Risk; Smoking ... Abstract: In a case-control analysis, we studied the effects of type of employment on laryngeal cancer risk using the interview ...
Complex and Multifaceted Therapy-Related Myeloid Neoplasm Following Laryngeal Cancer Treated with Cisplatin and Radiotherapy ... Niscola, P. (2013) "Complex and Multifaceted Therapy-Related Myeloid Neoplasm Following Laryngeal Cancer Treated with Cisplatin ... Key words, azacitidine, cisplatin, chronic myelomonocytic leukemia, laryngeal cancer, myelofibrosis, platinum, secondary ... BCR-ABL1 POSITIVE MYELOID NEOPLASMS: REVIEW OF LITERATURE , Mediterranean Journal of Hematology and Infectious Diseases: Vol. ...
Laryngeal Neoplasms - abnormal growths in the larynx (voice box) that can be cancerous or noncancerous. ... Laryngeal Paralysis - loss of function or feeling of one or both of the vocal folds caused by injury or disease to the nerves ... Also known as laryngeal framework surgery.. Tinnitus - sensation of a ringing, roaring, or buzzing sound in the ears or head. ... Laryngeal Nodules - noncancerous, callous-like growths on the inner parts of the vocal folds (vocal cords); usually caused by ...
The study aims to identify the effects of Notch1 signaling on the proliferation and apoptosis of laryngeal cancer cells in ... It is well-known that hypoxia has a variety of effects on the regulation of cell apoptosis and proliferation in human neoplasms ... into laryngeal cancer cells. After transfection for 24 hours, laryngeal cancer cells were collected for further research. ... Laryngeal cancer cell lines. The AMC-HN-8 and Tu212 cell lines were both obtained from the Institute of Biochemistry and Cell ...
No nasal or laryngeal neoplasms were attributed to exposure to molybdenum trioxide. Incidences of hyaline degeneration in the ... In both male and female mice, the incidences of hyperplasia of the laryngeal epithelium in level II of the larynx increased ... No increase in the incidences of lung neoplasms occurred in female rats. Incidences of chronic alveolar inflammation in male ...
Malignant breast neoplasm. Rare: Bladder carcinoma, benign brain neoplasm, esophageal carcinoma, malignant laryngeal neoplasm, ... Neoplasms Benign, Malignant, and Unspecified: Infrequent: Anaplastic thyroid cancer, angiomyolipoma, basal cell carcinoma, ... lipoma, rectal carcinoma, uterine neoplasm. Psychiatric: Infrequent: Increased libido, agitation, apathy, impaired ...
Baseline laryngeal functional status and overall health in advanced laryngeal SCC are associated with poor functional outcomes ... Laryngeal Neoplasms* / pathology * Retrospective Studies * Risk Factors * Squamous Cell Carcinoma of Head and Neck ... Conclusions: Baseline laryngeal functional status and overall health in advanced laryngeal SCC are associated with poor ... Risk Factors for Functional Outcomes in Advanced Laryngeal Squamous Cell Carcinoma Laryngoscope. 2023 Mar;133(3):594-600. doi: ...
LARYNGEAL NEOPL. Entry Term(s). Cancer of Larynx Cancer of the Larynx Laryngeal Cancer Larynx Cancer Larynx Neoplasms Neoplasms ... Otorhinolaryngologic Neoplasms [C04.588.443.665] * Ear Neoplasms [C04.588.443.665.312] * Laryngeal Neoplasms [C04.588.443.665. ... coord IM with histol type of neopl (IM); laryngeal polyps = LARYNGEAL NEOPLASMS (IM) + POLYPS (IM). Scope Note. Cancers or ... Neoplasms [C04] * Neoplasms by Site [C04.588] * Head and Neck Neoplasms [C04.588.443] * ...
Head and Neck Neoplasms, Radiotherapy, Drug Therapy, Laryngeal Neoplasms, Speech, Language and Hearing Sciences, Cirurgia de ... Speech, Language and Hearing Sciences, Public Health, Neoplasms, Diagnostic Imaging, General Surgery, ...
Pharyngeal Neoplasm;. Head and Neck Neoplasms;. Laryngeal Disease Investigational Drug(s). None ...
Recurrent respiratory papillomatosis (RRP) is the most common benign pediatric laryngeal neoplasm. Various adjuvant medical ... Merkel cell carcinoma (MCC) is a rare, rapidly growing, and aggressive dermatological neoplasm. It is commonly reported in ...
Laryngeal_Carcinoma,modify,24-FEB-06,(null),(null) C3156,Laryngeal_Neoplasm,modify,24-FEB-06,(null),(null) C13305,Laryngeal, ... Neoplasm C6955,Olfactory_Neural_Neoplasm,merge,24-FEB-06,C5121,Olfactory_Nerve_Neoplasm C6955,Olfactory_Neural_Neoplasm,retire, ... Neoplasm,merge,24-FEB-06,C53684,Benign_Connective_and_Soft_Tissue_Neoplasm C4880,Benign_Bone_Neoplasm,modify,24-FEB-06,(null),( ... Neoplasm,modify,24-FEB-06,(null),(null) C5822,Nerve_Plexus_Neoplasm,modify,24-FEB-06,(null),(null) C5119,Nerve_Root_Neoplasm, ...
Laryngeal Neoplasm Larynx Neoplasm Larynx Neoplasms Neoplasm, Laryngeal Neoplasm, Larynx Neoplasms, Laryngeal Neoplasms, Larynx ... Larynx Neoplasm. Larynx Neoplasms. Neoplasm, Laryngeal. Neoplasm, Larynx. Neoplasms, Laryngeal. Neoplasms, Larynx. ... Cancer, Laryngeal. Cancer, Larynx. Cancers, Laryngeal. Cancers, Larynx. Laryngeal Cancer. Laryngeal Cancers. Laryngeal Neoplasm ... Cancer, Laryngeal Cancer, Larynx Cancers, Laryngeal Cancers, Larynx Laryngeal Cancer Laryngeal Cancers Larynx Cancer Larynx ...
LARYNGEAL NEOPL. Entry Term(s). Cancer of Larynx Cancer of the Larynx Laryngeal Cancer Larynx Cancer Larynx Neoplasms Neoplasms ... Otorhinolaryngologic Neoplasms [C04.588.443.665] * Ear Neoplasms [C04.588.443.665.312] * Laryngeal Neoplasms [C04.588.443.665. ... coord IM with histol type of neopl (IM); laryngeal polyps = LARYNGEAL NEOPLASMS (IM) + POLYPS (IM). Scope Note. Cancers or ... Neoplasms [C04] * Neoplasms by Site [C04.588] * Head and Neck Neoplasms [C04.588.443] * ...
Wulff, N. B., Højager, A., Wessel, I., Dalton, S. O. & Homøe, P., apr. 2021, I: The Laryngoscope. 131, 4, s. 820-831 12 s.. Publikation: Bidrag til tidsskrift › Review › peer review ...
  • Radiotherapy in laryngeal carcinoma: can a panel of 13 markers predict response? (umassmed.edu)
  • Notch1 and Ki-67 expression in laryngeal squamous cell carcinoma (LSCC) tissue samples were detected by immunohistochemistry. (researchsquare.com)
  • Our study has demonstrated that hypoxia may promote cell proliferation and inhibit cell apoptosis of laryngeal carcinoma. (researchsquare.com)
  • Laryngeal carcinoma has been considered as a common malignancy of the head and neck. (researchsquare.com)
  • 9 ], our previous data has observed that the expression level of Notch1 in laryngeal cancer tissues is significantly higher than that in normal mucosal tissues, and was positively associated with lymph node metastasis and clinical stage [ 10 ], suggesting that aberrant Notch1 signaling may be involved in regulating the malignant process of laryngeal carcinoma. (researchsquare.com)
  • As mentioned above, the role of Notch1 signaling in regulating cellular proliferation and apoptosis of laryngeal carcinoma by in vitro studies with Hep-2 cells is also controversial. (researchsquare.com)
  • Chemoradiation for patients with laryngeal squamous cell carcinoma (SCC) may achieve organ preservation, but appropriate patient selection remains unknown. (nih.gov)
  • Merkel cell carcinoma (MCC) is a rare, rapidly growing, and aggressive dermatological neoplasm. (deepdyve.com)
  • Laryngeal papilloma carcinoma. (malaimare.ro)
  • Indicatii si Tehnici operatorii: Cordectomia se adreseaza cancerului treimii medii a corzii vocale T1,T2cu mobilitate pastrata a acesteia, leziunilor displazice ale corzilor laryngeal papilloma carcinoma si carcinomului in situ. (malaimare.ro)
  • Laryngeal tumor suspicion can be raised in the early laryngeal papilloma carcinoma by dysphonia, not accompanied by pain. (malaimare.ro)
  • Cordectomy can be done endoscopically, by transoral approach and laryngeal papilloma carcinoma open surgery through laringofissure. (malaimare.ro)
  • Patologie tumorala este o problema de sanatate publica laryngeal papilloma carcinoma continua crestere, unul dintre principalele scopuri ale lumii medicale fiind dezvoltarea metodelor de screening si detectie precoce, in stadii cat mai tratabile, a neoplaziilor. (malaimare.ro)
  • Simptomul de alarma, usor de remarcat de catre pacient si laryngeal papilloma carcinoma util descoperirii tumorii laringiene in bacterii filamentoase incipiente este disfonia, neinsotita de durere. (malaimare.ro)
  • Laryngeal papilloma carcinoma factori de risc citati sunt Human Papilloma Virus HPV - mai ales HPV 16, refluxul gastro-esofagian, expunerea la rumegus, laryngeal papilloma carcinoma, radiatii ionizante si diversi compusi chimici volatili, imunosupresia si susceptibilitatea genetica. (malaimare.ro)
  • Paraliziile laryngeal papilloma carcinoma sunt datorate lezarii nervului laringeu recurent, fie iatrogen chirurgical, in timpul manevrelor de intubatie oro trahealafie printr-un proces tumoral laryngeal papilloma carcinoma, tiroidian sau de mediastin superior. (malaimare.ro)
  • 8. Neuroendocrine neoplasms of the larynx: an overview. (nih.gov)
  • METHODS: Cisplatin and fluorouracil were given during weeks 1 and 4 of radiation to 115 patients with locoregionally advanced larynx or hypopharynx squamous cell cancer without cartilage invasion or laryngeal destruction. (duke.edu)
  • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. (icd10data.com)
  • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified ( C25.9 ). (icd10data.com)
  • Categories D37 - D44 , and D48 classify by site neoplasms of uncertain behavior, i.e., histologic confirmation whether the neoplasm is malignant or benign cannot be made. (icd10data.com)
  • What's New in Laryngeal and Hypopharyngeal Cancer Research and Treatment? (medlineplus.gov)
  • 10. Organ preservation surgery for laryngeal cancer. (nih.gov)
  • 13. Does vocal cord fixation preclude nonsurgical management of laryngeal cancer? (nih.gov)
  • 14. [A laryngeal cancer in pregnancy]. (nih.gov)
  • 16. Looking at laryngeal cancer. (nih.gov)
  • 17. Pathological validation of supracricoid partial laryngectomy in laryngeal cancer. (nih.gov)
  • Niscola, P. (2013) "Complex and Multifaceted Therapy-Related Myeloid Neoplasm Following Laryngeal Cancer Treated with Cisplatin and Radiotherapy", Mediterranean Journal of Hematology and Infectious Diseases , 5(1), p. e2013030. (mjhid.org)
  • Occupational risk for laryngeal cancer. (nih.gov)
  • In a case-control analysis, we studied the effects of type of employment on laryngeal cancer risk using the interview data from the Third National Cancer Survey. (nih.gov)
  • The study aims to identify the effects of Notch1 signaling on the proliferation and apoptosis of laryngeal cancer cells in hypoxic microenvironment. (researchsquare.com)
  • In laryngeal cancer cells, small interfering RNA (siRNA) technology was to inhibit Notch1 expression. (researchsquare.com)
  • Notch1 signalling may exert a pivotal role in regulating the proliferation and apoptosis resistance of laryngeal cancer cells under hypoxia. (researchsquare.com)
  • To date, the regulatory mechanism of the aberrant growth of laryngeal cancer cells has not been elucidated. (researchsquare.com)
  • Unfortunately, the regulatory effect and mechanisms of hypoxia on the proliferation and apoptosis of laryngeal cancer cells are still unclear. (researchsquare.com)
  • Accordingly, the purpose of current research was to further explore the effects of Notch1 signaling on the regulation of apoptosis and proliferation of laryngeal cancer cells in the hypoxic microenvironment, clarifying the regulatory role of Notch1 signaling in tumor progression. (researchsquare.com)
  • Survival impact of pre-treatment neutrophils on oropharyngeal and laryngeal cancer patients undergoing definitive radiotherapy. (ucdenver.edu)
  • Treatment outcomes and cost comparisons for older adults with T4 laryngeal squamous cell cancer. (ucdenver.edu)
  • Postextubation airway obstruction from occult laryngeal mass. (umassmed.edu)
  • Recurrent respiratory papillomatosis (RRP) is the most common benign pediatric laryngeal neoplasm. (deepdyve.com)
  • For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned. (icd10data.com)
  • Laryngeal Neoplasms" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
  • This study investigates pre-treatment risk factors associated with functional and survival outcomes after radiation-based therapy in patients with advanced laryngeal SCC. (nih.gov)
  • Baseline laryngeal functional status and overall health in advanced laryngeal SCC are associated with poor functional outcomes after radiation-based therapy, highlighting the importance of patient selection when deciding between surgical and non-surgical treatment plans. (nih.gov)
  • An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm. (icd10data.com)
  • A retrospective cohort study was performed on 75 adult patients with stage III or IV laryngeal SCC receiving definitive radiation-based therapy from 1997 to 2016 at a tertiary care center. (nih.gov)
  • 11. Laryngeal alveolar rhabdomyosarcoma involving the true vocal fold in an adult: Case report. (nih.gov)
  • 8. [Surgical management and preservation of laryngeal function for senile patients with advanced laryngeal carcinoma]. (nih.gov)
  • This article focuses on the use of CT imaging in the evaluation of the larynx, with particular focus on laryngeal neoplasia, trauma, foreign bodies, and radiation-induced changes. (medscape.com)
  • INTRODUCTION: A multitude of treatment modalities have been proposed in management of early laryngeal squamous cell cancers(SCC). (bvsalud.org)
  • 9. [Horizontal laryngectomy in treatment of laryngeal cancer--oncologic and function results]. (nih.gov)
  • The aggregate data are reassuring in excluding any excess risk of death from lung, laryngeal, soft tissue sarcoma, brain and lymphoid neoplasms, as well as cirrhosis. (nih.gov)
  • CT scanning has become the most commonly used technique for general laryngeal imaging. (medscape.com)
  • Salivary gland neoplasms most commonly appear in the sixth decade of life. (medscape.com)
  • A further study of laryngeal neoplasms in America. (nih.gov)
  • [ 1 ] The incidence of salivary gland neoplasms as a whole is approximately 5.5 cases per 100,000 individuals in the United States, with malignant neoplasms accounting for 0.9 cases per 100,000. (medscape.com)
  • The acquisition time for a CT image is extremely short (within a matter of seconds), which is quite useful for the laryngeal examination, as patients are generally required to hold their breath to reduce movement. (medscape.com)
  • Contrasting information was derived through a literature review by Louredo et al, which indicated that in pediatric patients, most salivary gland neoplasms (75.4%) are malignant. (medscape.com)
  • Salivary gland neoplasms occurred with slightly greater frequency in girls (57.4% of patients) than in boys. (medscape.com)
  • Failure in the development of the TES, as seen in laryngeal and laryngoesophageal cleft, results in a communication between the 2 lumens and allows for aspiration of esophageal contents. (medscape.com)
  • Failure of complete recanalization results in laryngeal or subglottic stenosis. (medscape.com)
  • Salivary gland neoplasms are rare in children. (medscape.com)
  • In children, 35% of salivary gland neoplasms are malignant. (medscape.com)
  • the lumen recanalizes later by the 10th week of gestation and, in doing so, helps form the laryngeal ventricles and true and false vocal cords. (medscape.com)
  • Some common salivary gland neoplasms are listed in the table below. (medscape.com)