Mice, Inbred C57BLRisk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.Models, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Diet: Regular course of eating and drinking adopted by a person or animal.Oxidative Stress: A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products (Sies, Oxidative Stress, 1991, pxv-xvi).Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.United StatesMice, Knockout: Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Cross-Sectional Studies: Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.Age Factors: Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Obesity: A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Case-Control Studies: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.Reactive Oxygen Species: Molecules or ions formed by the incomplete one-electron reduction of oxygen. These reactive oxygen intermediates include SINGLET OXYGEN; SUPEROXIDES; PEROXIDES; HYDROXYL RADICAL; and HYPOCHLOROUS ACID. They contribute to the microbicidal activity of PHAGOCYTES, regulation of signal transduction and gene expression, and the oxidative damage to NUCLEIC ACIDS; PROTEINS; and LIPIDS.Genetic Variation: Genotypic differences observed among individuals in a population.Genotype: The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.Muscle, Skeletal: A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.Prevalence: The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.Food Analysis: Measurement and evaluation of the components of substances to be taken as FOOD.Environmental Exposure: The exposure to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals.Cell Line: Established cell cultures that have the potential to propagate indefinitely.Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.Regression Analysis: Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.Mice, Transgenic: Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.Oxidation-Reduction: A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).History, 21st Century: Time period from 2001 through 2100 of the common era.Genetic Predisposition to Disease: A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.Apoptosis: One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.European Continental Ancestry Group: Individuals whose ancestral origins are in the continent of Europe.Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)Reverse Transcriptase Polymerase Chain Reaction: A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.Bankruptcy: The state of legal insolvency with assets taken over by judicial process so that they may be distributed among creditors.Gene Expression Regulation: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.Biological Markers: Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.Infant, Newborn: An infant during the first month after birth.History, 20th Century: Time period from 1901 through 2000 of the common era.Cohort Studies: Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.Polymorphism, Single Nucleotide: A single nucleotide variation in a genetic sequence that occurs at appreciable frequency in the population.Analysis of Variance: A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Vehicle Emissions: Gases, fumes, vapors, and odors escaping from the cylinders of a gasoline or diesel internal-combustion engine. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed & Random House Unabridged Dictionary, 2d ed)Beverages: Liquids that are suitable for drinking. (From Merriam Webster Collegiate Dictionary, 10th ed)Environmental Monitoring: The monitoring of the level of toxins, chemical pollutants, microbial contaminants, or other harmful substances in the environment (soil, air, and water), workplace, or in the bodies of people and animals present in that environment.Cell Line, Tumor: A cell line derived from cultured tumor cells.Liver: A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.Questionnaires: Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Antioxidants: Naturally occurring or synthetic substances that inhibit or retard the oxidation of a substance to which it is added. They counteract the harmful and damaging effects of oxidation in animal tissues.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.Sex Factors: Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.Blotting, Western: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.Socioeconomic Factors: Social and economic factors that characterize the individual or group within the social structure.Neurons: The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.Homeostasis: The processes whereby the internal environment of an organism tends to remain balanced and stable.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Health Status Disparities: Variation in rates of disease occurrence and disabilities between population groups defined by socioeconomic characteristics such as age, ethnicity, economic resources, or gender and populations identified geographically or similar measures.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Linear Models: Statistical models in which the value of a parameter for a given value of a factor is assumed to be equal to a + bx, where a and b are constants. The models predict a linear regression.Carbon Footprint: A measure of the total greenhouse gas emissions produced by an individual, organization, event, or product. It is measured in units of equivalent kilograms of CARBON DIOXIDE generated in a given time frame.Kinetics: The rate dynamics in chemical or physical systems.Air Pollutants: Any substance in the air which could, if present in high enough concentration, harm humans, animals, vegetation or material. Substances include GASES; PARTICULATE MATTER; and volatile ORGANIC CHEMICALS.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.Phylogeny: The relationships of groups of organisms as reflected by their genetic makeup.Alleles: Variant forms of the same gene, occupying the same locus on homologous CHROMOSOMES, and governing the variants in production of the same gene product.History, 19th Century: Time period from 1801 through 1900 of the common era.Mitochondria: Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)Energy Metabolism: The chemical reactions involved in the production and utilization of various forms of energy in cells.Biomechanical Phenomena: The properties, processes, and behavior of biological systems under the action of mechanical forces.Sequence Analysis, DNA: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.China: A country spanning from central Asia to the Pacific Ocean.Protein Binding: The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.Disabled Persons: Persons with physical or mental disabilities that affect or limit their activities of daily living and that may require special accommodations.Dairy Products: Raw and processed or manufactured milk and milk-derived products. These are usually from cows (bovine) but are also from goats, sheep, reindeer, and water buffalo.Fast Foods: Prepared food that is ready to eat or partially prepared food that has a final preparation time of a few minutes or less.Environment: The external elements and conditions which surround, influence, and affect the life and development of an organism or population.Geography, Medical: The area of medicine concerned with the effects on health and disease due to geographic factors such as CLIMATE, environmental conditions, and geographic location.Polymorphism, Genetic: The regular and simultaneous occurrence in a single interbreeding population of two or more discontinuous genotypes. The concept includes differences in genotypes ranging in size from a single nucleotide site (POLYMORPHISM, SINGLE NUCLEOTIDE) to large nucleotide sequences visible at a chromosomal level.Agriculture: The science, art or practice of cultivating soil, producing crops, and raising livestock.African Americans: Persons living in the United States having origins in any of the black groups of Africa.Myocardium: The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.Up-Regulation: A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.Ethnic Groups: A group of people with a common cultural heritage that sets them apart from others in a variety of social relationships.Calcium: A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.Disease Progression: The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.Environmental Health: The science of controlling or modifying those conditions, influences, or forces surrounding man which relate to promoting, establishing, and maintaining health.Greenhouse Effect: The effect of GLOBAL WARMING and the resulting increase in world temperatures. The predicted health effects of such long-term climatic change include increased incidence of respiratory, water-borne, and vector-borne diseases.Glucose: A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.Endocrine System Diseases: Pathological processes of the ENDOCRINE GLANDS, and diseases resulting from abnormal level of available HORMONES.Fruit: The fleshy or dry ripened ovary of a plant, enclosing the seed or seeds.Smoking: Inhaling and exhaling the smoke of burning TOBACCO.Blood Pressure: PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.Proteins: Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.Atherosclerosis: A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.Animals, Newborn: Refers to animals in the period of time just after birth.Cost of Illness: The personal cost of acute or chronic disease. The cost to the patient may be an economic, social, or psychological cost or personal loss to self, family, or immediate community. The cost of illness may be reflected in absenteeism, productivity, response to treatment, peace of mind, or QUALITY OF LIFE. It differs from HEALTH CARE COSTS, meaning the societal cost of providing services related to the delivery of health care, rather than personal impact on individuals.Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Industrial Waste: Worthless, damaged, defective, superfluous or effluent material from industrial operations.Endothelium, Vascular: Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.Exercise: Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure.Authorship: The profession of writing. Also the identity of the writer as the creator of a literary production.Causality: The relating of causes to the effects they produce. Causes are termed necessary when they must always precede an effect and sufficient when they initiate or produce an effect. Any of several factors may be associated with the potential disease causation or outcome, including predisposing factors, enabling factors, precipitating factors, reinforcing factors, and risk factors.Gene Expression Profiling: The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.World Health: The concept pertaining to the health status of inhabitants of the world.History, 18th Century: Time period from 1701 through 1800 of the common era.Myocytes, Cardiac: Striated muscle cells found in the heart. They are derived from cardiac myoblasts (MYOBLASTS, CARDIAC).Writing: The act or practice of literary composition, the occupation of writer, or producing or engaging in literary work as a profession.Particulate Matter: Particles of any solid substance, generally under 30 microns in size, often noted as PM30. There is special concern with PM1 which can get down to PULMONARY ALVEOLI and induce MACROPHAGE ACTIVATION and PHAGOCYTOSIS leading to FOREIGN BODY REACTION and LUNG DISEASES.Cell Proliferation: All of the processes involved in increasing CELL NUMBER including CELL DIVISION.Lung: Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.Longitudinal Studies: Studies in which variables relating to an individual or group of individuals are assessed over a period of time.Logistic Models: Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.Reference Values: The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.Chlorogenic Acid: A naturally occurring phenolic acid which is a carcinogenic inhibitor. It has also been shown to prevent paraquat-induced oxidative stress in rats. (From J Chromatogr A 1996;741(2):223-31; Biosci Biotechnol Biochem 1996;60(5):765-68).Australia: The smallest continent and an independent country, comprising six states and two territories. Its capital is Canberra.Computer Simulation: Computer-based representation of physical systems and phenomena such as chemical processes.Evolution, Molecular: The process of cumulative change at the level of DNA; RNA; and PROTEINS, over successive generations.Polymerase Chain Reaction: In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.Macrophages: The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)Cytokines: Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.Air Movements: The motion of air currents.Enzyme Inhibitors: Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.Housing: Living facilities for humans.Vegetables: A food group comprised of EDIBLE PLANTS or their parts.Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Atmosphere: The gaseous envelope surrounding a planet or similar body. (From Random House Unabridged Dictionary, 2d ed)Food: Any substances taken in by the body that provide nourishment.Stress, Mechanical: A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area.Insulin: A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).Cell Survival: The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.DNA Primers: Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Food Contamination: The presence in food of harmful, unpalatable, or otherwise objectionable foreign substances, e.g. chemicals, microorganisms or diluents, before, during, or after processing or storage.Energy Intake: Total number of calories taken in daily whether ingested or by parenteral routes.Healthcare Disparities: Differences in access to or availability of medical facilities and services.Mice, Inbred BALB CEnvironmental Pollutants: Substances or energies, for example heat or light, which when introduced into the air, water, or land threaten life or health of individuals or ECOSYSTEMS.African Continental Ancestry Group: Individuals whose ancestral origins are in the continent of Africa.Bacterial Proteins: Proteins found in any species of bacterium.Epithelial Cells: Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.Kidney: Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.Models, Genetic: Theoretical representations that simulate the behavior or activity of genetic processes or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.Ecosystem: A functional system which includes the organisms of a natural community together with their environment. (McGraw Hill Dictionary of Scientific and Technical Terms, 4th ed)Cognition Disorders: Disturbances in mental processes related to learning, thinking, reasoning, and judgment.Air Pollution, Indoor: The contamination of indoor air.Air Pollution: The presence of contaminants or pollutant substances in the air (AIR POLLUTANTS) that interfere with human health or welfare, or produce other harmful environmental effects. The substances may include GASES; PARTICULATE MATTER; or volatile ORGANIC CHEMICALS.RussiaModels, Molecular: Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.Residence Characteristics: Elements of residence that characterize a population. They are applicable in determining need for and utilization of health services.Inflammation Mediators: The endogenous compounds that mediate inflammation (AUTACOIDS) and related exogenous compounds including the synthetic prostaglandins (PROSTAGLANDINS, SYNTHETIC).Hydrogen Peroxide: A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.Stress, Physiological: The unfavorable effect of environmental factors (stressors) on the physiological functions of an organism. Prolonged unresolved physiological stress can affect HOMEOSTASIS of the organism, and may lead to damaging or pathological conditions.Diet Records: Records of nutrient intake over a specific period of time, usually kept by the patient.Phosphorylation: The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.Wounds and Injuries: Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity.Income: Revenues or receipts accruing from business enterprise, labor, or invested capital.Oligonucleotide Array Sequence Analysis: Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.Seasons: Divisions of the year according to some regularly recurrent phenomena usually astronomical or climatic. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Canada: The largest country in North America, comprising 10 provinces and three territories. Its capital is Ottawa.Cluster Analysis: A set of statistical methods used to group variables or observations into strongly inter-related subgroups. In epidemiology, it may be used to analyze a closely grouped series of events or cases of disease or other health-related phenomenon with well-defined distribution patterns in relation to time or place or both.Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.Endoplasmic Reticulum Stress: Various physiological or molecular disturbances that impair ENDOPLASMIC RETICULUM function. It triggers many responses, including UNFOLDED PROTEIN RESPONSE, which may lead to APOPTOSIS; and AUTOPHAGY.DNA: A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).Flow Cytometry: Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.Membrane Proteins: Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.Food Supply: The production and movement of food items from point of origin to use or consumption.Depression: Depressive states usually of moderate intensity in contrast with major depression present in neurotic and psychotic disorders.Haplotypes: The genetic constitution of individuals with respect to one member of a pair of allelic genes, or sets of genes that are closely linked and tend to be inherited together such as those of the MAJOR HISTOCOMPATIBILITY COMPLEX.Cell Movement: The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.Databases, Factual: Extensive collections, reputedly complete, of facts and data garnered from material of a specialized subject area and made available for analysis and application. The collection can be automated by various contemporary methods for retrieval. The concept should be differentiated from DATABASES, BIBLIOGRAPHIC which is restricted to collections of bibliographic references.Gene-Environment Interaction: The combined effects of genotypes and environmental factors together on phenotypic characteristics.Genome, Human: The complete genetic complement contained in the DNA of a set of CHROMOSOMES in a HUMAN. The length of the human genome is about 3 billion base pairs.Fibroblasts: Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.Oxygen: An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.Transcription Factors: Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.Food Habits: Acquired or learned food preferences.Food Industry: The industry concerned with processing, preparing, preserving, distributing, and serving of foods and beverages.Nutrition Surveys: A systematic collection of factual data pertaining to the nutritional status of a human population within a given geographic area. Data from these surveys are used in preparing NUTRITION ASSESSMENTS.Immunity, Innate: The capacity of a normal organism to remain unaffected by microorganisms and their toxins. It results from the presence of naturally occurring ANTI-INFECTIVE AGENTS, constitutional factors such as BODY TEMPERATURE and immediate acting immune cells such as NATURAL KILLER CELLS.Comorbidity: The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.Internationality: The quality or state of relating to or affecting two or more nations. (After Merriam-Webster Collegiate Dictionary, 10th ed)Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.Drinking: The consumption of liquids.
Hawken, Paul (2007). Blessed Unrest: How the Largest Movement in the World Came into Being and Why No One Saw It Coming. New ... Contributor, EW. "Paul Hawken". EcoWatch. EcoWatch. Retrieved 8 September 2016. "Global Green USA Millennium Awards". Global ... Hawken, Paul (2007). Blessed Unrest: How the Largest Movement in the World Came Into Being, and Why No One Saw It Coming (1 ed ... Grover, Sami (21 June 2007). "WISER Earth: User Created Directory of 'the Largest Movement on Earth'". Treehugger. Retrieved 15 ...
The single largest Japanese diaspora in any city is in São Paulo. In 1958 the census counted 120,000 Japanese in the city and ... Contributor Reporter). "Japanese Culture and Architecture in São Paulo." The Rio Times. November 8, 2011. Retrieved on March 19 ... "All You Need To Know About Sao Paulo, Brazil's Largest City." Forbes. July 12, 2013. Retrieved on March 20, 2014. Lesser, A ... In the 1980s, São Paulo Japanese supplementary schools were larger than those in other communities. In 1992 the São Paulo ...
... meaning they are larger than large Siberian tiger males, who are themselves usually larger than the larger lion species. ... Bryden, A.H. (contributor). "Animal Life and the World of Nature" (1902-1903, bound partwork). Iles, G. At Home In The Zoo ( ... Hercules, the largest non-obese liger, is recognised by the Guinness Book of World Records as the largest living cat on Earth, ... Largest living cat "Hercules, 922-Pound Liger, Is The World's Largest Living Cat (PHOTOS)". The Huffington Post. Retrieved 31 ...
"Elizabeth Matheson's contributor biography". outh Writ Large quarterly magazine. Retrieved 1 February 2014. Interior ...
"Contributors: Tolkien". Oxford English Dictionary Online. Retrieved 3 October 2012. Considine, John (1998). "Why do large ... If the editors felt that the dictionary would have to grow larger, it would; it was an important work, and worth the time and ... Another earlier large dictionary is the Grimm brothers' dictionary of the German language, begun in 1838 and completed in 1961 ... Despite its impressive size, the OED is neither the world's largest nor the earliest exhaustive dictionary of a language. ...
Seal blubber contains large amounts of vitamin E, selenium, and other antioxidants, which may[original research?] reduce the ... Damage to cells by free radicals is a theorized[by whom?] contributor to oxidative diseases.) Whale blubber, which tastes like ... However, this is not indicative of larger whales' ability to retain heat better, as the thickness of a whale's blubber does not ... Since toothed whales are high on the food chain, they likely consume large amounts of industrial pollutants (bioaccumulation); ...
The Cullen Foundation is still[when?] a large contributor to the school. Cullen had been in his early life a Democrat, but ... He would drill deeper into the ground, despite technical issues and the higher cost, in order to reach the large oil deposits. ... Cullen was heavily involved in the petroleum industry, was a large supporter of the University of Houston, and longtime ... He would continue to make large donations to the university throughout his lifetime. ...
"Jane Mayer, Contributor, The New Yorker". Newyorker.com. Retrieved 2017-09-26. "WEDDINGS; Jane M. Mayer, William Hamilton". The ... Mayer, Jane (March 27, 2017). "The Reclusive Hedge-Fund Tycoon Behind The Trump Presidency". A Reporter At Large. The New ... Mayer, Jane (October 10, 2011). "State for Sale". A Reporter At Large. The New Yorker. Retrieved 2017-09-22. Mayer, Jane ( ... in his capacity as advisor to reclusive contributor Robert Mercer. Hedge fund director Mercer, joined in his efforts by his ...
Another contributor was novelist Una Troy. Illustrators whose work was published in Our Boys included W. C. Mills, Gordon ... The magazine had a large circulation for Ireland, and advertising kept the magazine ticking over financially. A list of ...
Uihlein is the PAC's largest contributor. Chairman Proft and Richard Uihlein are associated with the Illinois Policy Institute ...
"Kupinatao.com largest TaoBao partner uses Virto Commerce" (PDF). kupinatao. Retrieved 16 June 2015. "Virto Commerce Certified ... "Virto Commerce Contributors". GitHub. Retrieved 2015-09-09. Bowen, David. "EPiServer Acquires Business of e-Commerce Solution ... Virto Commerce is designed to be implemented by medium to large companies looking to launch B2C and Business-to-business ...
Saputo is the largest dairy processor in Canada, one of the top three dairy processors in Argentina, and among the top four in ... Ben Popken, TODAY contributor (November 19, 2012). "Twinkie's last stand: It's up to a mediator". Lifeinc.today.com. Retrieved ... It became Canada's largest producer of mozzarella in the 1980s.[non-primary source needed] In 1988, Saputo expanded to the ... "Saputo buys 3rd-largest Argentine dairy company". The Globe and Mail. "Financial Information - Investors". saputo.com. ...
The Ethiopian Army is the largest contributor. On 15 January 2016, Major General Hassen Ebrahim Mussa was appointed the United ...
Coplin is a contributor to USA Today.[citation needed] He is the director of highly selective Policy Studies undergraduate ... Today, despite its strict entrance requirements, it is one of the largest interdisciplinary undergraduate majors at Syracuse ...
It comprises 10 large-scale woodcuts, executed between 1999 and 2005. Huck is currently working on a 14-triptych cycle of ... He is a regular contributor to BLAB! of Fantagraphics Books. His work is influenced by Albrecht Dürer, José Guadalupe Posada, R ... Tom Huck (born 1971) is an American printmaker best known for his large-scale satirical woodcuts. He lives and works in St. ... Huck is best known for creating large-scale woodcuts acting as both satirical narratives and social criticism. He says in his ...
The single largest contributor is fertilizer use. But the burning of fossil fuels actually dominates the problem in some ... Similarly the Earth may not be able to react to large deviations in critical parameters. In his book The Revenge of Gaia, he ... Disruption of the global nitrogen cycle is one clear example: it is likely that a large fraction of people on Earth would not ... For example, the large projected demand for HFCs could significantly contribute to climate change." Aerosol particles in the ...
Tourism is a large contributor to Central Florida's economy. The area has economically diversified in the past decade. As a ... Agriculture has occupied a large portion of Central Florida's economy, with winter strawberries,[23] citrus, timber, vegetables ... their two metropolitan areas blend together in the area of Lakeland to make up a larger contiguous population center often ... Oldakowski found that Floridians surveyed identified Central Florida as comprising a large swath of peninsular Florida.[1] This ...
Their style is broadly Heavy Metal, but with a large number of other influences including: Industrial, Goth, Romantic. In 2009 ... The band's music is a collaboration between various musicians; Llexi Leon being the only permanent musical contributor. ...
Creators are scheduled to take on the stage and pitch their Projects to a larger audience. This helps promote their idea and ... prizes were reduced and the contributor list shrank. The street festival portion of the event was combined with Downtown ... Pitch Decks are platform for Creators to reach a large audience and communicate their ideas in a short period of time. ... One Spark claims it was the world's largest crowdfunding event. Organizers retooled One Spark for 2016, held April 6-7. For ...
Parker Towing was his largest contributor, providing $24,000.00. $493,856, 41% of his contributions came from large individual ...
Terminal 1 of the SRIA, is large with an area measuring 16,468 m2 (177,260 sq ft). Terminal 1 Departures Hall entrance The ... SRIA is an important contributor to Samarinda's economy. About 6 airlines will operate flights from the airport to 15 cities ... It is also home to Kaltim's largest passenger terminal buildings. The airport will be operated by Airport Authority Samarinda ...
Nurdles are a major contributor to marine debris. During a three-month study of Orange County beaches researchers found them to ... Waterborne nurdles may either be a raw material of plastic production, or from larger chunks of plastics. A major concentration ... Plastic particle water pollution is a type of marine debris originating from plastic particles utilized in manufacturing large ...
"Top Organization Contributors , OpenSecrets". www.opensecrets.org. Retrieved 2016-11-13. Kirkland, Rik; Contributor, Fortune ( ... Under Stern's leadership SEIU became the largest union in the AFL-CIO, and the fastest growing union in the world. Then after ... contributor, By Rik Kirkland , Fortune. "SEIU union boss Andy Stern is the new face of labor - October 16, 2006". archive. ... During the years of Stern's leadership, the SEIU became the largest political action committee in the United States, and ...
When a small part of a large such extent is overwritten, the resulting copy-on-write may create three new extents: a small one ... "Btrfs Contributors at kernel.org". kernel.org. 2016-01-18. Retrieved 2016-01-20. "Suse Documentation: Storage Administration ... This makes for efficient seeks in large files with many extents, because the correct extent for any given file offset can be ... This means user applications iterating over and opening files in a large directory would thus generate many more disk seeks ...
Each contributor to Verity! lives in a different part of the world, so they record in their own locations and are connected via ... The other four cast members rotate, except for large celebratory episodes where all six come together for the show. ... The Verity! contributors are all Doctor Who fans and live in Canada, the United States, the United Kingdom and Australia. The ... Verity! is not scripted, except for some contributors, like Ensign and Stanish, who use occasional notes in order to stay on ...
Most cases of diabetes involve many genes, with each being a small contributor to an increased probability of becoming a type 2 ... type 2 diabetes is the largest cause of nontraumatic blindness and kidney failure.[25] It has also been associated with an ...
The financial sector is the largest contributor, overall, to political campaign. One of the largest credit card banks, MBNA, ... his largest contributor was Maryland Bank, National Association. Hunh? Oh, you may know them as MBNA-- they changed their name ... Women Would be Among the Hardest Hit. Women represent the single largest group in bankruptcy, with households headed by women ... Making matters worse, many large credit card banks or their affiliated holding companies are facing increased scrutiny over ...
MarketWatch: Illness and Injury as Contributors to Bankruptcy. Health Affairs, 2 Feb. 2005. ... A larger category - any medical bankruptcy" - also covered those who cited addiction, or uncontrolled gambling, childbirth, or ...
Mental illness is the largest contributor to disability, according to a report card on the worlds health, The Global Burden of ... Mental illness is the largest contributor to disability, according to a report card on the worlds health, The Global Burden of ... Mental illness the largest contributor to disability worldwide. by University of New South Wales ... Citation: Mental illness the largest contributor to disability worldwide (2012, December 14) retrieved 25 September 2020 from ...
Large contributor to Abbott, Patrick pleaded guilty to domestic violence charge 2 years ago Filed under Local Politics at Feb ... Hiles was Abbotts third-largest contributor and was among the 40 individuals and couples that Abbott named to the prestigious ... AUSTIN - One of the largest donors to Gov. Greg Abbott and Lt. Gov. Dan Patrick pleaded guilty two years ago to a domestic ...
India is largest contributor of illegally imported medicines in Switzerland. Home India is largest contributor of illegally ... India is largest contributor of illegally imported medicines in Switzerland. India was the largest contributor of the illegally ...
Added Fructose Larger Contributor To Diabetes Than Carbohydrates. By Staff Reporter Feb 02, 2015 12:09 PM EST * ...
A Framework for Assessing Mortality and Morbidity After Large-Scale Disasters by the National Academies of Sciences, ... Contributors. National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Health Sciences ... A Framework for Assessing Mortality and Morbidity After Large-Scale Disasters reviews and describes the current state of the ... eBook files are now available for a large number of reports on the NAP.edu website. If an eBook is available, youll see the ...
The Chesapeake Bay, the largest estuary in the continental United States, weaves its way south from Maryland, collecting waters ... Argonne Supercomputer Hosts Largest-Ever Combustion Engine Flow Simulation. By Oliver Peckham ... conducting the largest-ever simulation of flow inside of an internal combustion engine. ... making it the worlds largest seven-nanom Read more… ... Contributors. Tiffany Trader Managing Editor. George Leopold ...
ITALY: CINECA - Largest computing center in Italy; The Marconi Supercomputer is among the worlds fastest energy efficient ... "Last year, we set a goal to become the worlds largest provider of TOP500 computing systems by 2020. We have reached that goal ... SPAIN: Barcelona Supercomputing Center - Largest supercomputer in Spain; Voted "Worlds Most Beautiful Data Center" by ... "Lenovo has an industry leading ability to bring deep innovations and a comprehensive approach to execute on the largest scale ...
Contributor Notes. INCLUDE WHEN CITING Published online November 4, 2016; DOI: 10.3171/2016.8.PEDS16229.. Correspondence ... Using a large cohort of pediatric patients undergoing first-time shunt insertion, we failed to identify an ideal target within ... Ventricular catheter entry site and not catheter tip location predicts shunt survival: a secondary analysis of 3 large ... Overall, the population is a heterogeneous sample from large American (15), Canadian (3), and European (4) centers. There were ...
Netherlands largest net contributor EU this century The Netherlands is relatively the largest net contributor to the UK. ... Randstad economy fourth largest in Europe The Randstad region is the largest economic urban region in the European Union (EU) ... Netherlands has the seventh largest trade surplus in the world Worldwide, the Netherlands has the seventh largest trade surplus ... The United States have by far the largest trade deficit in the goods trade. Three EU countries with large trade deficits in ...
Largest-ever North Korea sanctions a footnote in freewheeling Trump CPAC speech ... OnCall+ Wellness contributors from Duke include: Martin Binks, Ph.D., Elisabetta Politi, R.D., Gerald K. Endress, M.S., Adele ... OnCall+ Contributors. Martin Binks, Ph.D., Duke Diet and Fitness Center Dr. Martin Binks is Director of Behavioral Health, ...
Nonfiction: Large and Largesse. by Robert C. Morgan JUL-AUG 2009 , Books. Given the task at hand, this is a formidable book a ... Brooklyn Rail Contributor Robert C. Morgan Robert C. Morgan is a writer, international art critic, curator, poet, lecturer, and ... Situated adjacent to Seoul, the country s capital on the edge of the border with North Korea Incheon is the fourth largest city ... Known for his sparse, large-scale brush marks on empty canvas and his sculpture in which boulders are placed on glass or ...
Larger Than Life: The Kevyn Aucoin Story chronicles the life of deceased makeup artist, Kevyn Aucoin, an icon of 80s and 90s ... Contributor Im a lifestyle and fashion features editor who writes for heritage magazines like Harpers Bazaar and Vogue. My ... Larger Than Life shares Aucoins journey from a small town in Louisiana as an adopted child in a family of six where he ... Larger Than Life shares Aucoins journey from a small town in Louisiana as an adopted child in a family of six where he ...
Large and Medium Manufacturing Indicator: Indonesia. Contributor. Indonesia. Badan Pusat Statistik. Publisher. Badan Pusat ... Rent and save from the worlds largest eBookstore. Read, highlight, and take notes, across web, tablet, and phone. ... Total Keuntungan Jual Beli Kinds of input Klui Komposisi Biaya Input Komposisi Nilai Output lainnya Other Materials LARGE AND ... gb-gplus-shareLarge and Medium Manufacturing Indicator. ... 0 Reviewshttps://books.google.com/books/about/Large_and_Medium_ ...
Contributor Opinions expressed by Forbes Contributors are their own. On October 12, 1810 Crown Prince Ludwig, soon to become ... Here is everything you need to know about the biggest tent in the worlds largest beer festival. ... Here is everything you need to know about the biggest tent in the worlds largest beer festival. ...
About Evelyne Davos: I love to explore my sexual thoughts and fantasies. If you feel the same, I dare you to come and fantasize together.I love to
... and Larger (5+ units) have pros & cons. Something for you to think about and which will help you shape what type or how large a ... 1st Investment: Larger Multi vs. Duplex/Tri/Quad.... 7 Replies * ... Starting large with no knowledge, background, support network, ... Andrew Ginsburg anything larger than four units is commercial. I have to agree with @Kyle Gregg go for a triplex and see if you ... Anyway, I wanted to ask the experts here what the advantages are of starting my REI career with a smaller multi vs a large ...
Network Contributors. Pierre Mitchell , Jason Busch Magnus Bergfors , Andrew Karpie Michael Lamoureux , Xavier Olivera Nick ... Freelancer Limited - Anatomy of a Large Global Work Intermediation Platform [PRO]. Andrew Karpie ...
However, although ambient particle concentrations and cooking are additional sources of PM2.5, SHS is the largest contributor ... FIGURE 2. Correlation between mean PM2.5 and smoker density* in five U.S. large-hub airports† with designated indoor smoking ... FIGURE 1. Mean levels of PM2.5 in nine large-hub airports with and without designated indoor smoking areas,* by area type - ... Levels of PM2.5 in nine large-hub airports with and without designated indoor smoking areas,* by sampled area (N = 49) - United ...
This post was published on the now-closed HuffPost Contributor platform. Contributors control their own work and posted freely ... Skin: How to Care for Our Largest Organ. Healthy skin is vital for our survival both emotionally and physically. To boost these ... With proper sun exposure, skin plays a large role in manufacturing Vitamin D. ... remember that your skin absorbs a large percentage of what you put on it. Here is a closer look at how much we rely on our skin ...
Psammoma Bodies in a Large Myoepithelioma. Melo, Marcela Pessoa de; Silva, Diego Filipe Bezerra; Ribeiro, Rodrigo Alves; More ...
Contributor. Rich Shea was an editor-at-large for Teacher Magazine. Call of Duty ...
Tesla to Go Private: Brace for the Largest Ever Buyout. August 08, 2018, 08:47:00 AM EDT By Tirthankar Chakraborty, Zacks.com ... Tesla Buyout Would be Largest in History. At the price of $420 a share, by the way, a buyout would cost nearly $72 billion, ... He said that "being public means that there are large numbers of people who have the incentive to attack the company." Musk, ... 3 Crazy Facts About Canopy Growths Largest Acquisition in Marijuana.... *Facebook (FB) Q1 Earnings to Gain on Ad & Stories ...
Contributor 2,121 posts 44 reviews Save Reply 3. Re: car rental for larger family - advice? ... Someone posted recently a trip report where they mentioned having trouble navigating some of the switchbacks with larger suv I ... Cruz Bay, wed all pile into the the larger one to go to dinner. ... car rental for larger family - advice? - St. John Forum. * ... I could only imagine trying to do that in a larger SUV. ... 1. Re: car rental for larger family - advice? 21 Feb 2014, 15: ...
  • A larger category - 'any medical bankruptcy" - also covered those who cited addiction, or uncontrolled gambling, childbirth, or the death of a family member. (factcheck.org)
  • It has become very clear that getting to 2 C, and especially 1.5 C, is very dependent on our ability to remove large amounts of CO2 from the atmosphere," Naomi Vaughan, a climate scientist at the University of East Anglia, told the opening plenary of the Climate Engineering Conference 2017. (spacedaily.com)
  • Beckett, Michael A. , Coles, Simon J. , Horton, Peter N. and Jones, Charlotte L. (2017) Polyborate anions partnered with large non-metal cations: triborate(1-), pentaborate(1-), and heptaborate(2-) salts. (soton.ac.uk)
  • The Ryan White HIV/AIDS Program, the largest HIV-specific discretionary grant program in the U.S. and third largest source of federal funding for HIV care (behind Medicaid and Medicare), is funded at $2.3 billion in the budget request (a $58.8 million or 2.5% decrease over the FY 2017 omnibus level). (kff.org)
  • India was the largest contributor of the illegally imported medicines in Switzerland in 2015, Swissmedic - a Switzerland government agency for therapeutic products - has said. (chemdiv.com)
  • The large grey babbler ( Turdoides malcolmi ) is a member of the Leiothrichidae family found in India. (eol.org)
  • See [https://www.familysearch.org/learn/wiki/en/Clay_County,_Illinois#Boundary_Changes Clay County, Illinois Boundary Changes] as an example. (familysearch.org)
  • AUSTIN - One of the largest donors to Gov. Greg Abbott and Lt. Gov. Dan Patrick pleaded guilty two years ago to a domestic violence charge that included an accusation he choked a woman into unconsciousness. (dallasnews.com)
  • [ 10 ] More reliable high-level coupled-cluster EOM calculations of small model systems predicted even larger coupling constants. (pubmedcentralcanada.ca)
  • Our Medium Red Nitrile Level 1 Cut Resistant Dipped Work Gloves have a ANSI and EN cut rating of 1, TDM cut rating of A, and a Puncture rating of 1.These work gloves are ideal for material handling and general purpose remodeling applications. (homedepot.com)
  • More than 25,000 churches have signed up for My Hope, including some of the largest congregations in America who see this as an opportunity to share the Gospel "at a level never quite seen before. (christianpost.com)
  • Large Scale Network-Centric Distributed Systems provides in-depth coverage ranging from ground-level hardware issues (such as buffer organization, router delay, and flow control) to the high-level issues immediately concerning application or system users (including parallel programming, middleware, and OS support for such computing systems). (wiley.com)
  • Even with a statistical dead heat, the finding is remarkable because of assumptions that urban areas have a big innovation advantage from factors such as larger skilled-labor pools and better information and supply networks, said report co-author Tim Wojan in an email. (huffingtonpost.com)
  • In this work, we investigate links between the formulation of the flow of marginals of reversible diffusion processes as gradient flows in the space of probability measures and path wise large deviation principles for sequences of such processes. (archives-ouvertes.fr)
  • I have also read that renting the car on St Thomas and taking the auto barge over is an option - this also seemed like a good alternative given our larger group size. (tripadvisor.co.uk)
  • Now, researchers from Argonne National Laboratory have applied supercomputing power to push the limits of these processes, conducting the largest-ever simulation of flow inside of an internal combustion engine. (hpcwire.com)
  • While large rural manufacturers had an innovation edge, that finding did not hold true for small and medium-sized rural manufacturers, the study shows. (huffingtonpost.com)
  • A new BU study, the largest ever on childhood anxiety, will compare online and in-person therapy for effectiveness. (bu.edu)
  • These are questions that study coleader Pincus and fellow researchers on both the Charles River and Medical Campuses and elsewhere will study over the next five years in what Pincus calls the largest-ever research project of its kind. (bu.edu)
  • As an application, we study large deviations from the hydrodynamic limit for two variants of the Ginzburg-Landau model endowed with Kawasaki dynamics. (archives-ouvertes.fr)
  • An Adynxx pain drug has failed to meet the main goal of a mid-stage study, but the company instead points to results in a subset of patients that it says are strong enough to justify advancing the treatment into a larger Phase 3 clinical trial. (xconomy.com)
  • Lenovo has an industry leading ability to bring deep innovations and a comprehensive approach to execute on the largest scale and highest performance, working with our customers to design supercomputing systems that meet their needs in terms of design and compute power," said Madhu Matta, Vice President and General Manager of HPC and AI at Lenovo Data Center Group. (hpcwire.com)
  • While the transformations that we have been computing follow the large deformation approach in that they are the result of the evolution of a smooth time-dependent velocity vector field, the final shape analysis via linearizing around template coordinates using displacement vector fields has provided a practical basis for this approach [ 1 ]. (pubmedcentralcanada.ca)
  • A Modular Approach to Monitoring, Assessing and Managing Large Marine Ecosystems (K. Sherman, E.D. Anderson). (elsevier.com)
  • Our experiments show that this approach enables to query large models in a restricted amount of memory with an acceptable performance. (inria.fr)
  • Larger Than Life shares Aucoin's journey from a small town in Louisiana as an adopted child in a family of six where he experienced life-threatening homophobic experiences as an openly gay man in the south. (forbes.com)
  • I have heard some say every now and again that you have the same issues wether it's a small or larger property. (biggerpockets.com)
  • I personally just assume bypassing the small properties if large ones are an option for you. (biggerpockets.com)
  • My partner and I both use them and she had small hands and I have large hands. (homedepot.com)
  • Small number changes on the pH scale actually mean large changes in acidity. (gc.ca)
  • The same plague of us-or-them absolutism that has infested the small community of self-described "climate skeptics," wrecking any chance they could have played a positive role in critiquing mainstream climatology, now threatens to overwhelm the much larger "safe food" movement, too. (scientificamerican.com)
  • On Monday, we posted a photo by EV Grieve reader William Klayer showing a very large bone on the sidewalk. (evgrieve.com)
  • Blessed Unrest, How the Largest Movement in the World Came into Being and Why No One Saw It Coming, published in May 2007, argues that a vast "movement with no name" is forming involving environmental, social justice, and indigenous rights organizations. (wikipedia.org)
  • Large manufacturing firms in rural America are at least as likely as similar urban firms to use innovative methods that can contribute to job creation and increased earnings, a new report says. (huffingtonpost.com)
  • Stillbirths are the largest contributor to perinatal mortality, but current classification systems consistently report about two thirds of stillbirths as being unexplained. (bmj.com)
  • Therefore I wasn't sure if it was also beneficial to find a larger deal and try and build in the 10%ish contingency for a management company or get my hands dirty on a smaller property and learn the guts of it. (biggerpockets.com)
  • For more than a year, volunteers, staff and social workers have questioned the health and safety of Portland's largest shelter for families with children. (opb.org)
  • Which medications in the drug class Antineoplastics, PI3K Delta Inhibitors are used in the treatment of Diffuse Large Cell Lymphoma? (medscape.com)
  • 2 Medicare is the largest federal funder of HIV care and treatment, followed by Medicaid. (kff.org)
  • The migration process must ensure maximum data integrity and our solutions and experience in large-scale migrations will ensure we achieve this. (marinelink.com)
  • Although such devices are not yet commercially available, and covering a body of water may seem impractical on a large scale, setting such a system aloft would provide a hugely important side benefit: preventing drinking water reservoirs from shrinking. (ieee.org)
  • Unlike traditional large-scale evangelistic events, the outreach is designed for Christians, whether they be a pastor, ministry leader, or lay person, to invite guests and host a viewing in a chosen venue, possibly even a home. (christianpost.com)
  • Evolving from the fields of high-performance computing and networking, large scale network-centric distributed systems continues to grow as one of the most important topics in computing and communication and many interdisciplinary areas. (wiley.com)
  • Large Scale Network-Centric Distributed Systems is an incredibly useful resource for practitioners, postgraduate students, postdocs, and researchers. (wiley.com)
  • Once you get your process and systems down, then ramping up to a larger number of units will be smoother as you know what to expect. (biggerpockets.com)
  • In large-deformation diffeomorphic metric mapping (LDDMM), the diffeomorphic matching of images are modeled as evolution in time, or a flow, of an associated smooth velocity vector field v controlling the evolution. (pubmedcentralcanada.ca)
  • At these energy facilities, water stored in a large pool uphill is allowed to flow down through turbines to produce electricity during periods of peak demand. (ieee.org)
  • What is the clinical history large cell transformation of mycosis fungoides cutaneous T-cell lymphoma (CTCL)? (medscape.com)
  • In its fourth year, The Color Run is one of the largest event series in history. (courant.com)
  • Preparations for perhaps the largest evangelistic event in U.S. history continue for Billy Graham and his ministry team with just three weeks to go before the famed preacher's message "The Cross," filmed from his home in North Carolina, is planned for broadcast through multiple platforms. (christianpost.com)
  • Before construction began, every area was subject to detailed archaeological investigation: doing so has exposed a rich history of human settlement since Neolithic times and has provided a unique insight into the history of a large sample of the landscape of North Buckinghamshire . (wikipedia.org)
  • Yesterday, Students for Carbon Dividends announced that more than 350 student government groups from colleges and universities in all 50 states, representing more than four million students, signed onto the "Students Government Leaders' Statement on Carbon Dividends," one of the largest statements of student body presidents in U.S. history. (redgreenandblue.org)
  • Multnomah County evacuated its largest shelter for homeless families late Wednesday, due to safety concerns over damage from a leaking roof. (opb.org)
  • I selected medium to medium-large zucchini's (in the 5-6-inch length range), and - with a surgeon's precision - sliced them into strips, grilled, then served them daintily coiled with goat cheese and red pepper. (annarbor.com)
  • The range is still wide and the population large (tens of thousands of individuals in various countries). (iucnredlist.org)
  • The US Large-Cap Growth Equity Composite seeks long-term capital appreciation by investing primarily in common stocks of large-cap growth companies based in the U.S. (troweprice.com)
  • When this single cell thick membrane is damaged, the holes become larger and particles that are not supposed to come in, can. (apricotpower.com)
  • Anyway, I wanted to ask the experts here what the advantages are of starting my REI career with a smaller multi vs a large multi? (biggerpockets.com)