Compounds, either natural or synthetic, which block development of the growing insect.
Paired or fused ganglion-like bodies in the head of insects. The bodies secrete hormones important in the regulation of metamorphosis and the development of some adult tissues.
Juvenile hormone analog and insect growth regulator used to control insects by disrupting metamorphosis. Has been effective in controlling mosquito larvae.
A steroid hormone that regulates the processes of MOLTING or ecdysis in insects. Ecdysterone is the 20-hydroxylated ECDYSONE.
Profound physical changes during maturation of living organisms from the immature forms to the adult forms, such as from TADPOLES to frogs; caterpillars to BUTTERFLIES.
The blood/lymphlike nutrient fluid of some invertebrates.
Proteins found in any species of insect.
An inactive stage between the larval and adult stages in the life cycle of insects.
A nutritional reservoir of fatty tissue found mainly in insects and amphibians.
Steroids that bring about MOLTING or ecdysis in insects. Ecdysteroids include the endogenous insect hormones (ECDYSONE and ECDYSTERONE) and the insect-molting hormones found in plants, the phytoecdysteroids. Phytoecdysteroids are natural insecticides.
Insects of the order Dictyoptera comprising several families including Blaberidae, BLATTELLIDAE, Blattidae (containing the American cockroach PERIPLANETA americana), Cryptocercidae, and Polyphagidae.
The active production and accumulation of VITELLINS (egg yolk proteins) in the non-mammalian OOCYTES from circulating precursors, VITELLOGENINS. Vitellogenesis usually begins after the first MEIOSIS and is regulated by estrogenic hormones.
Wormlike or grublike stage, following the egg in the life cycle of insects, worms, and other metamorphosing animals.
Phospholipoglycoproteins produced in the fat body of egg-laying animals such as non-mammalian VERTEBRATES; ARTHROPODS; and others. Vitellogenins are secreted into the HEMOLYMPH, and taken into the OOCYTES by receptor-mediated ENDOCYTOSIS to form the major yolk proteins, VITELLINS. Vitellogenin production is under the regulation of steroid hormones, such as ESTRADIOL and JUVENILE HORMONES in insects.
Major egg yolk proteins from egg-laying animals such as non-mammalian VERTEBRATES; ARTHROPODS; and others. They are high-density lipoglycoproteins derived from circulating precursors, VITELLOGENINS. Vitellins serve as nutrients for the growing non-mammalian embryos (EMBRYO, NONMAMMALIAN).
Chemical substances having a specific regulatory effect on the activity of a certain organ or organs. The term was originally applied to substances secreted by various ENDOCRINE GLANDS and transported in the bloodstream to the target organs. It is sometimes extended to include those substances that are not produced by the endocrine glands but that have similar effects.
Insects of the suborder Heterocera of the order LEPIDOPTERA.
Enzymes which catalyze the hydrolysis of carboxylic acid esters with the formation of an alcohol and a carboxylic acid anion.
A genus of sphinx or hawk moths of the family Sphingidae. These insects are used in molecular biology studies during all stages of their life cycle.
A large order of insects comprising the butterflies and moths.
A steroid hormone that regulates the processes of MOLTING or ecdysis in insects.
Insect members of the superfamily Apoidea, found almost everywhere, particularly on flowers. About 3500 species occur in North America. They differ from most WASPS in that their young are fed honey and pollen rather than animal food.
A genus of small beetles of the family Tenebrionidae; T. confusum is the "confused flour beetle".
Natural hormones secreted by the THYROID GLAND, such as THYROXINE, and their synthetic analogs.
A genus of silkworm MOTHS in the family Bombycidae of the order LEPIDOPTERA. The family contains a single species, Bombyx mori from the Greek for silkworm + mulberry tree (on which it feeds). A native of Asia, it is sometimes reared in this country. It has long been raised for its SILK and after centuries of domestication it probably does not exist in nature. It is used extensively in experimental GENETICS. (From Borror et al., An Introduction to the Study of Insects, 4th ed, p519)
Sesquiterpenes are a class of terpenes consisting of three isoprene units, forming a 15-carbon skeleton, which can be found in various plant essential oils and are known for their diverse chemical structures and biological activities, including anti-inflammatory, antimicrobial, and cytotoxic properties.
A colorless liquid extracted from oils of plants such as citronella, neroli, cyclamen, and tuberose. It is an intermediate step in the biological synthesis of cholesterol from mevalonic acid in vertebrates. It has a delicate odor and is used in perfumery. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Follicle-stimulating hormone stimulates GAMETOGENESIS and the supporting cells such as the ovarian GRANULOSA CELLS, the testicular SERTOLI CELLS, and LEYDIG CELLS. FSH consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity.
Hormones secreted by insects. They influence their growth and development. Also synthetic substances that act like insect hormones.
A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Luteinizing hormone regulates steroid production by the interstitial cells of the TESTIS and the OVARY. The preovulatory LUTEINIZING HORMONE surge in females induces OVULATION, and subsequent LUTEINIZATION of the follicle. LUTEINIZING HORMONE consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH and FSH), but the beta subunit is unique and confers its biological specificity.
A genus of beetles which infests grain products. Its larva is called mealworm.
The class Insecta, in the phylum ARTHROPODA, whose members are characterized by division into three parts: head, thorax, and abdomen. They are the dominant group of animals on earth; several hundred thousand different kinds having been described. Three orders, HEMIPTERA; DIPTERA; and SIPHONAPTERA; are of medical interest in that they cause disease in humans and animals. (From Borror et al., An Introduction to the Study of Insects, 4th ed, p1)
A plant genus of the family CYPERACEAE. SESQUITERPENES are found in some of the species.
The functional hereditary units of INSECTS.
A polypeptide hormone (84 amino acid residues) secreted by the PARATHYROID GLANDS which performs the essential role of maintaining intracellular CALCIUM levels in the body. Parathyroid hormone increases intracellular calcium by promoting the release of CALCIUM from BONE, increases the intestinal absorption of calcium, increases the renal tubular reabsorption of calcium, and increases the renal excretion of phosphates.
Hormones produced by invertebrates, usually insects, mollusks, annelids, and helminths.
A genus of mosquitoes (CULICIDAE) frequently found in tropical and subtropical regions. YELLOW FEVER and DENGUE are two of the diseases that can be transmitted by species of this genus.
A decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE. GnRH is produced by neurons in the septum PREOPTIC AREA of the HYPOTHALAMUS and released into the pituitary portal blood, leading to stimulation of GONADOTROPHS in the ANTERIOR PITUITARY GLAND.
Steroid hormones produced by the GONADS. They stimulate reproductive organs, germ cell maturation, and the secondary sex characteristics in the males and the females. The major sex steroid hormones include ESTRADIOL; PROGESTERONE; and TESTOSTERONE.
A species of fruit fly much used in genetics because of the large size of its chromosomes.
The total process by which organisms produce offspring. (Stedman, 25th ed)
Plant-eating orthopterans having hindlegs adapted for jumping. There are two main families: Acrididae and Romaleidae. Some of the more common genera are: Melanoplus, the most common grasshopper; Conocephalus, the eastern meadow grasshopper; and Pterophylla, the true katydid.
Traumatic or experimentally induced separation of the head from the body in an animal or human.
An order of insects, restricted mostly to the tropics, containing at least eight families. A few species occur in temperate regions of North America.
The immature stage in the life cycle of those orders of insects characterized by gradual metamorphosis, in which the young resemble the imago in general form of body, including compound eyes and external wings; also the 8-legged stage of mites and ticks that follows the first moult.
Ductless glands that secrete HORMONES directly into the BLOOD CIRCULATION. These hormones influence the METABOLISM and other functions of cells in the body.
The family Gryllidae consists of the common house cricket, Acheta domesticus, which is used in neurological and physiological studies. Other genera include Gryllotalpa (mole cricket); Gryllus (field cricket); and Oecanthus (tree cricket).
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
A family of insects in the order Dictyoptera (COCKROACHES), including genera Blattella, Parcoblatta, and Symploce.
Specific high affinity binding proteins for THYROID HORMONES in target cells. They are usually found in the nucleus and regulate DNA transcription. These receptors are activated by hormones that leads to transcription, cell differentiation, and growth suppression. Thyroid hormone receptors are encoded by two genes (GENES, ERBA): erbA-alpha and erbA-beta for alpha and beta thyroid hormone receptors, respectively.
A colorless liquid used as a solvent and an antiseptic. It is one of the ketone bodies produced during ketoacidosis.
A 191-amino acid polypeptide hormone secreted by the human adenohypophysis (PITUITARY GLAND, ANTERIOR), also known as GH or somatotropin. Synthetic growth hormone, termed somatropin, has replaced the natural form in therapeutic usage such as treatment of dwarfism in children with growth hormone deficiency.
Diazonium compounds are organic derivatives containing the general formula R-N2+X-, where R represents an aryl or alkyl group, and X- is an anion such as bromide or chloride, formed by the reaction of amines with nitrous acid in an acidic medium.
The process of laying or shedding fully developed eggs (OVA) from the female body. The term is usually used for certain INSECTS or FISHES with an organ called ovipositor where eggs are stored or deposited before expulsion from the body.
An anterior pituitary hormone that stimulates the ADRENAL CORTEX and its production of CORTICOSTEROIDS. ACTH is a 39-amino acid polypeptide of which the N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Upon further tissue-specific processing, ACTH can yield ALPHA-MSH and corticotrophin-like intermediate lobe peptide (CLIP).
An order of the class Insecta. Wings, when present, number two and distinguish Diptera from other so-called flies, while the halteres, or reduced hindwings, separate Diptera from other insects with one pair of wings. The order includes the families Calliphoridae, Oestridae, Phoridae, SARCOPHAGIDAE, Scatophagidae, Sciaridae, SIMULIIDAE, Tabanidae, Therevidae, Trypetidae, CERATOPOGONIDAE; CHIRONOMIDAE; CULICIDAE; DROSOPHILIDAE; GLOSSINIDAE; MUSCIDAE; TEPHRITIDAE; and PSYCHODIDAE. The larval form of Diptera species are called maggots (see LARVA).
Organs and other anatomical structures of non-human vertebrate and invertebrate animals.
A suborder of HEMIPTERA, called true bugs, characterized by the possession of two pairs of wings. It includes the medically important families CIMICIDAE and REDUVIIDAE. (From Dorland, 28th ed)
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action during the developmental stages of an organism.
Periodic casting off FEATHERS; HAIR; or cuticle. Molting is a process of sloughing or desquamation, especially the shedding of an outer covering and the development of a new one. This phenomenon permits growth in ARTHROPODS, skin renewal in AMPHIBIANS and REPTILES, and the shedding of winter coats in BIRDS and MAMMALS.
Pheromones that elicit sexual attraction or mating behavior usually in members of the opposite sex in the same species.
Hormones secreted by the PITUITARY GLAND including those from the anterior lobe (adenohypophysis), the posterior lobe (neurohypophysis), and the ill-defined intermediate lobe. Structurally, they include small peptides, proteins, and glycoproteins. They are under the regulation of neural signals (NEUROTRANSMITTERS) or neuroendocrine signals (HYPOTHALAMIC HORMONES) from the hypothalamus as well as feedback from their targets such as ADRENAL CORTEX HORMONES; ANDROGENS; ESTROGENS.
Slender-bodies diurnal insects having large, broad wings often strikingly colored and patterned.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
The reproductive organ (GONADS) in female animals. In vertebrates, the ovary contains two functional parts: the OVARIAN FOLLICLE for the production of female germ cells (OOGENESIS); and the endocrine cells (GRANULOSA CELLS; THECA CELLS; and LUTEAL CELLS) for the production of ESTROGENS and PROGESTERONE.
INSECTS of the order Coleoptera, containing over 350,000 species in 150 families. They possess hard bodies and their mouthparts are adapted for chewing.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
Proteins that originate from insect species belonging to the genus DROSOPHILA. The proteins from the most intensely studied species of Drosophila, DROSOPHILA MELANOGASTER, are the subject of much interest in the area of MORPHOGENESIS and development.
Peptides released by NEURONS as intercellular messengers. Many neuropeptides are also hormones released by non-neuronal cells.
A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.
Proteins found usually in the cytoplasm or nucleus that specifically bind steroid hormones and trigger changes influencing the behavior of cells. The steroid receptor-steroid hormone complex regulates the transcription of specific genes.
A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.

Deletion analysis of the Drosophila Inscuteable protein reveals domains for cortical localization and asymmetric localization. (1/457)

The Drosophila Inscuteable protein acts as a key regulator of asymmetric cell division during the development of the nervous system [1] [2]. In neuroblasts, Inscuteable localizes into an apical cortical crescent during late interphase and most of mitosis. During mitosis, Inscuteable is required for the correct apical-basal orientation of the mitotic spindle and for the asymmetric segregation of the proteins Numb [3] [4] [5], Prospero [5] [6] [7] and Miranda [8] [9] into the basal daughter cell. When Inscuteable is ectopically expressed in epidermal cells, which normally orient their mitotic spindle parallel to the embryo surface, these cells reorient their mitotic spindle and divide perpendicularly to the surface [1]. Like the Inscuteable protein, the inscuteable RNA is asymmetrically localized [10]. We show here that inscuteable RNA localization is not required for Inscuteable protein localization. We found that a central 364 amino acid domain - the Inscuteable asymmetry domain - was necessary and sufficient for Inscuteable localization and function. Within this domain, a separate 100 amino acid region was required for asymmetric localization along the cortex, whereas a 158 amino acid region directed localization to the cell cortex. The same 158 amino acid fragment could localize asymmetrically when coexpressed with the full-length protein, however, and could bind to Inscuteable in vitro, suggesting that this domain may be involved in the self-association of Inscuteable in vivo.  (+info)

Sibling cell fate in the Drosophila adult external sense organ lineage is specified by prospero function, which is regulated by Numb and Notch. (2/457)

Specification of cell fate in the adult sensory organs is known to be dependent on intrinsic and extrinsic signals. We show that the homeodomain transcription factor Prospero (Pros) acts as an intrinsic signal for the specification of cell fates within the mechanosensory lineage. The sensory organ precursors divide to give rise to two secondary progenitors - PIIa and PIIb. Pros is expressed in PIIb, which gives rise to the neuron and thecogen cells. Loss of Pros function affects the identity of PIIb and neurons fail to differentiate. Pros misexpression is sufficient for the transformation of PIIa to PIIb fate. The expression of Pros in the normal PIIb cell appears to be regulated by Notch signaling.  (+info)

A functional analysis of inscuteable and its roles during Drosophila asymmetric cell divisions. (3/457)

Cellular diversity in the Drosophila central nervous system is generated through a series of asymmetric cell divisions in which one progenitor produces two daughter cells with distinct fates. Asymmetric basal cortical localisation and segregation of the determinant Prospero during neuroblast cell divisions play a crucial role in effecting distinct cell fates for the progeny sibling neuroblast and ganglion mother cell. Similarly asymmetric localisation and segregation of the determinant Numb during ganglion mother cell divisions ensure that the progeny sibling neurons attain distinct fates. The most upstream component identified so far which acts to organise both neuroblast and ganglion mother cell asymmetric divisions is encoded by inscuteable. The Inscuteable protein is itself asymmetrically localised to the apical cell cortex and is required both for the basal localisation of the cell fate determinants during mitosis and for the orientation of the mitotic spindle along the apical/basal axis. Here we define the functional domains of Inscuteable. We show that aa252-578 appear sufficient to effect all aspects of its function, however, the precise requirements for its various functions differ. The region, aa288-497, is necessary and sufficient for apical cortical localisation and for mitotic spindle (re)orientation along the apical/basal axis. A larger region aa288-540 is necessary and sufficient for asymmetric Numb localisation and segregation; however, correct localisation of Miranda and Prospero requires additional sequences from aa540-578. The requirement for the resolution of distinct sibling neuronal fates appears to coincide with the region necessary and sufficient for Numb localisation (aa288-540). Our data suggest that apical localisation of the Inscuteable protein is a necessary prerequisite for all other aspects of its function. Finally, we show that although inscuteable RNA is normally apically localised, RNA localisation is not required for protein localisation or any aspects of inscuteable function.  (+info)

Effect of juvenile hormone on the central nervous processing of sex pheromone in an insect. (4/457)

Behavioral sex pheromone responsiveness in the male moth Agrotis ipsilon was previously shown to be controlled by juvenile hormone (JH). However, this morphogenetic hormone did not change the sensitivity of antennae to sex pheromones. To analyze the possible involvement of JH in the central integration of the female-produced sex pheromone, we investigated the pheromone response of olfactory antennal lobe (AL) interneurons in male A. ipsilon as a function of age and JH status by using intracellular recordings. When the antennae were stimulated with the sex pheromone blend, the sensitivity of olfactory AL neurons increased with age, as does the JH-dependent behavioral and physiological development of A. ipsilon males. Furthermore, males surgically deprived of JH showed a significant decrease in the sensitivity of the AL neurons. JH injection in operated or in young males restored or induced, respectively, a high sensitivity of the AL neurons. JH seems likely to be involved in the plasticity of the adult insect brain by modulating the central nervous processing of olfactory information, thus allowing mate recognition and reproduction at the optimal time.  (+info)

Cell division genes promote asymmetric interaction between Numb and Notch in the Drosophila CNS. (5/457)

Cell intrinsic and cell extrinsic factors mediate asymmetric cell divisions during neurogenesis in the Drosophila embryo. In the NB4-2->GMC-1->RP2/sib lineage, one of the well-studied neuronal lineages in the ventral nerve cord, the Notch (N) signaling interacts with the asymmetrically localized Numb (Nb) to specify sibling neuronal fates to daughter cells of GMC-1. In this current study, we have investigated asymmetric cell fate specifications by N and Nb in the context of cell cycle. We have used loss-of-function mutations in N and nb, cell division mutants cyclinA (cycA), regulator of cyclin A1 (rca1) and string/cdc25 phosphatase (stg), and the microtubule destabilizing agent, nocodazole, to investigate this issue. We report that the loss of cycA, rca1 or stg leads to a block in the division of GMC-1, however, this GMC-1 exclusively adopts an RP2 identity. While the loss of N leads to the specification of RP2 fates to both progeny of GMC-1 and loss of nb results in the specification of sib fates to these daughter cells, the GMC-1 in the double mutant between nb and cycA assumes a sib fate. These epistasis results indicate that both N and nb function downstream of cell division genes and that progression through cell cycle is required for the asymmetric localization of Nb. In the absence of entry to metaphase, the Nb protein prevents the N signaling from specifying sib fate to the RP2/sib precursor. These results are also consistent with our finding that the sib cell is specified as RP2 in N; nb double mutants. Finally, our results show that nocodazole-arrested GMC-1 in wild-type embryos randomly assumes either an RP2 fate or a sib fate. This suggests that microtubules are involved in mediating the antagonistic interaction between Nb and N during RP2 and sib fate specification.  (+info)

The Drosophila homeobox genes zfh-1 and even-skipped are required for cardiac-specific differentiation of a numb-dependent lineage decision. (6/457)

A series of inductive signals are necessary to subdivide the mesoderm in order to allow the formation of the progenitor cells of the heart. Mesoderm-endogenous transcription factors, such as those encoded by twist and tinman, seem to cooperate with these signals to confer correct context and competence for a cardiac cell fate. Additional factors are likely to be required for the appropriate specification of individual cell types within the forming heart. Similar to tinman, the zinc finger- and homeobox-containing gene, zfh-1, is expressed in the early mesoderm and later in the forming heart, suggesting a possible role in heart development. Here, we show that zfh-1 is specifically required for formation of the even-skipped (eve)-expressing subset of pericardial cells (EPCs), without affecting the formation of their siblings, the founders of a dorsal body wall muscle (DA1). In addition to zfh-1, mesodermal eve itself appears to be needed for correct EPC differentiation, possibly as a direct target of zfh-1. Epistasis experiments show that zfh-1 specifies EPC development independently of numb, the lineage gene that controls DA1 founder versus EPC cell fate. We discuss the combinatorial control mechanisms that specify the EPC cell fate in a spatially precise pattern within the embryo.  (+info)

NUMB localizes in the basal cortex of mitotic avian neuroepithelial cells and modulates neuronal differentiation by binding to NOTCH-1. (7/457)

The importance of lateral inhibition mediated by NOTCH signaling is well demonstrated to control neurogenesis both in invertebrates and vertebrates. We have identified the chicken homolog of Drosophila numb, which suppresses NOTCH signaling. We show that chicken NUMB (c-NUMB) protein is localized to the basal cortex of mitotic neuroepithelial cells, suggesting that c-NUMB regulates neurogenesis by the modification of NOTCH signaling through asymmetrical cell division. Consistent with this suggestion, we show (1) that c-NUMB interferes with the nuclear translocation of activated c-NOTCH-1 through direct binding to the PEST sequence in the cytoplasmic domain of c-NOTCH-1 and (2) that c-NUMB interferes with c-NOTCH-1-mediated inhibition of neuronal differentiation.  (+info)

Experience-expectant plasticity in the mushroom bodies of the honeybee. (8/457)

Worker honeybees (Apis mellifera) were reared in social isolation in complete darkness to assess the effects of experience on growth of the neuropil of the mushroom bodies (MBs) during adult life. Comparison of the volume of the MBs of 1-day-old and 7-day-old bees showed that a significant increase in volume in the MB neuropil occurred during the first week of life in bees reared under these highly deprived conditions. All regions of the MB neuropil experienced a significant increase in volume with the exception of the basal ring. Measurement of titers of juvenile hormone JH) in a subset of bees indicated that, as in previous studies, these rearing conditions induced in some bees the endocrine state of high JH associated with foraging, but there was no correlation between JH titer and volume of MB neuropil. Treatment of another subset of dark-reared bees with the JH analog, methoprene, also had no effect of the growth of the MB neuropil. These results demonstrate that there is a phase of MB neuropil growth early in the adult life of bees that occurs independent of light or any form of social interaction. Together with previous findings showing that an increase in MB neuropil volume begins around the time that orientation flights occur and then continues throughout the phase of life devoted to foraging, these results suggest that growth of the MB neuropil in adult bees may have both experience-expectant and experience-dependent components.  (+info)

Juvenile hormones (JHs) are a class of sesquiterpenoid compounds that play a crucial role in the regulation of insect development, reproduction, and other physiological processes. They are primarily produced by the corpora allata, a pair of endocrine glands located in the head of insects.

JHs are essential for maintaining the larval or nymphal stage of insects, preventing the expression of adult characteristics during molting. As the concentration of JH decreases in the hemolymph (insect blood), a molt to the next developmental stage occurs, and if the insect has reached its final instar, it will metamorphose into an adult.

In addition to their role in development, JHs also influence various aspects of insect reproductive physiology, such as vitellogenesis (yolk protein synthesis), oocyte maturation, and spermatogenesis. Furthermore, JHs have been implicated in regulating diapause (a period of suspended development during unfavorable environmental conditions) and caste determination in social insects like bees and ants.

Overall, juvenile hormones are vital regulators of growth, development, and reproduction in insects, making them attractive targets for the development of novel pest management strategies.

The corpora allata are small endocrine glands found in the head of insects, located near the brain. They are part of the insect endocrine system and produce important hormones that regulate various physiological processes, including growth, development, reproduction, and molting. The most well-known hormone produced by the corpora allata is juvenile hormone (JH), which plays a crucial role in maintaining the larval or nymphal stage of insects and preventing metamorphosis into the adult form. As the insect grows and develops, the production of JH decreases, allowing for the initiation of metamorphosis and the emergence of the adult form.

Methoprene is an insect growth regulator (IGR) that disrupts the developmental process in insects, preventing them from reaching maturity and reproducing. It works by mimicking the natural hormones found in insects, specifically juvenile hormone, which regulates their molting and metamorphosis. By interfering with this process, methoprene causes immature insects to continue molting without ever becoming adults, or it prevents larvae from transforming into pupae or adults.

Methoprene is commonly used in pest control applications, including public health, agriculture, and household settings, to control a wide range of insect pests, such as mosquitoes, fleas, ticks, ants, cockroaches, and stored product pests. It has low toxicity to non-target organisms, including mammals, making it a relatively safe option for use in sensitive environments. However, like any pesticide, methoprene should be used responsibly and according to label instructions to minimize potential risks to human health and the environment.

Ecdysterone is a type of steroid hormone that occurs naturally in various plants and animals. In animals, ecdysterones are known to play important roles in the growth, development, and reproduction of arthropods, such as insects and crustaceans. They are called "ecdysteroids" and are crucial for the process of molting, in which the arthropod sheds its exoskeleton to grow a new one.

In plants, ecdysterones are believed to function as growth regulators and defense compounds. Some studies suggest that they may help protect plants against pests and pathogens.

Ecdysterone has also gained attention in the context of human health and performance enhancement. While it is not a hormone naturally produced by the human body, some research suggests that ecdysterone may have anabolic effects, meaning it could potentially promote muscle growth and improve physical performance. However, more studies are needed to confirm these findings and establish the safety and efficacy of ecdysterone supplementation in humans.

It is important to note that the use of performance-enhancing substances, including ecdysterone, may be subject to regulations and anti-doping rules in various sports organizations. Always consult with a healthcare professional before starting any new supplement regimen.

Biological metamorphosis is a complex process of transformation that certain organisms undergo during their development from embryo to adult. This process involves profound changes in form, function, and structure of the organism, often including modifications of various body parts, reorganization of internal organs, and changes in physiology.

In metamorphosis, a larval or juvenile form of an animal is significantly different from its adult form, both morphologically and behaviorally. This phenomenon is particularly common in insects, amphibians, and some fish and crustaceans. The most well-known examples include the transformation of a caterpillar into a butterfly or a tadpole into a frog.

The mechanisms that drive metamorphosis are regulated by hormonal signals and genetic programs. In many cases, metamorphosis is triggered by environmental factors such as temperature, moisture, or food availability, which interact with the organism's internal developmental cues to initiate the transformation. The process of metamorphosis allows these organisms to exploit different ecological niches at different stages of their lives and contributes to their evolutionary success.

Hemolymph is not a term typically used in human medicine, but it is commonly used in the study of invertebrates, particularly arthropods such as insects and crustaceans. Hemolymph is the fluid that circulates within the open circulatory system of these animals, serving multiple functions similar to both blood and lymphatic systems in vertebrates.

In simpler terms, hemolymph is a combined fluid that performs the functions of both blood and lymph in invertebrates. It serves as a transport medium for nutrients, waste products, hormones, and immune cells (hemocytes) throughout the body. Hemolymph does not contain red and white blood cells like human blood; instead, hemocytes are the primary cellular components responsible for immune responses and wound healing in these animals.

I'm sorry for any confusion, but "Insect Proteins" is not a recognized medical term. However, I can provide some information about insect protein from a nutritional and food science perspective.

Insect proteins refer to the proteins that are obtained from insects. Insects are a rich source of protein, and their protein content varies by species. For example, mealworms and crickets have been found to contain approximately 47-63% and 60-72% protein by dry weight, respectively.

In recent years, insect proteins have gained attention as a potential sustainable source of nutrition due to their high protein content, low environmental impact, and the ability to convert feed into protein more efficiently compared to traditional livestock. Insect proteins can be used in various applications such as food and feed additives, nutritional supplements, and even cosmetics.

However, it's important to note that the use of insect proteins in human food is not widely accepted in many Western countries due to cultural and regulatory barriers. Nonetheless, research and development efforts continue to explore the potential benefits and applications of insect proteins in the global food system.

I must clarify that the term 'pupa' is not typically used in medical contexts. Instead, it is a term from the field of biology, particularly entomology, which is the study of insects.

In insect development, a pupa refers to a stage in the life cycle of certain insects undergoing complete metamorphosis. During this phase, the larval body undergoes significant transformation and reorganization within a protective casing called a chrysalis (in butterflies and moths) or a cocoon (in other insects). The old larval tissues are broken down and replaced with new adult structures. Once this process is complete, the pupal case opens, and the adult insect emerges.

Since 'pupa' is not a medical term, I couldn't provide a medical definition for it. However, I hope this explanation helps clarify its meaning in the context of biology.

A "fat body" is not a medical term that is typically used to describe human anatomy. It is more commonly used in the context of insects and other invertebrates, where it refers to a specialized tissue that functions to store energy in the form of fat.

However, in humans, we do have adipose tissue, which is the medical term for body fat. Adipose tissue is found throughout the body, but is particularly concentrated in certain areas such as the abdomen, hips, and thighs. It serves a variety of functions, including storing energy, insulating the body, and producing hormones that regulate metabolism and appetite.

If you are looking for information on obesity or excess body fat in humans, there are many medical resources available to help you understand these topics better.

Ecdysteroids are a class of steroid hormones that are primarily known for their role in the regulation of molting and growth in arthropods, such as insects and crustaceans. They are structurally similar to vertebrate steroid hormones, such as estrogens and androgens, but have different physiological functions.

Ecdysteroids bind to specific receptors in the cell nucleus, leading to changes in gene expression that regulate various processes related to molting and growth, including the synthesis of new exoskeleton components and the breakdown of old ones. They also play a role in other physiological processes, such as reproduction, development, and stress response.

In recent years, ecdysteroids have attracted interest in the medical community due to their potential therapeutic applications. Some studies suggest that certain ecdysteroids may have anabolic effects, promoting muscle growth and protein synthesis, while others have shown anti-inflammatory, antioxidant, and immunomodulatory properties. However, more research is needed to fully understand the potential therapeutic uses of ecdysteroids in humans.

Cockroaches are not a medical condition or disease. They are a type of insect that can be found in many parts of the world. Some species of cockroaches are known to carry diseases and allergens, which can cause health problems for some people. Cockroach allergens can trigger asthma symptoms, especially in children. Additionally, cockroaches can contaminate food and surfaces with bacteria and other germs, which can lead to illnesses such as salmonellosis and gastroenteritis.

If you have a problem with cockroaches in your home or workplace, it is important to take steps to eliminate them to reduce the risk of health problems. This may include cleaning up food and water sources, sealing entry points, and using pesticides or hiring a professional pest control service.

Vitellogenesis is the process of producing and accumulating yolk proteins in the oocytes (immature ovum or egg cell) of females in preparation for fertilization and embryonic development. This process is primarily seen in oviparous animals, such as birds, fish, and insects, where the yolk serves as a source of nutrients for the developing embryo.

The yolk proteins are synthesized mainly in the liver under the control of estrogen hormones and are then transported to the oocytes through the bloodstream. Once inside the oocytes, these proteins are taken up by a process called pinocytosis, where they are enclosed in vesicles and fuse with lysosomes to form yolk granules. The accumulation of these yolk granules provides the developing embryo with essential nutrients such as lipids, carbohydrates, and proteins.

In addition to its role in reproduction, vitellogenesis has been used as a biomarker for environmental estrogen exposure in non-target organisms, as the production of yolk proteins can be induced by estrogenic compounds found in pollutants such as pesticides and industrial chemicals.

A larva is a distinct stage in the life cycle of various insects, mites, and other arthropods during which they undergo significant metamorphosis before becoming adults. In a medical context, larvae are known for their role in certain parasitic infections. Specifically, some helminth (parasitic worm) species use larval forms to infect human hosts. These invasions may lead to conditions such as cutaneous larva migrans, visceral larva migrans, or gnathostomiasis, depending on the specific parasite involved and the location of the infection within the body.

The larval stage is characterized by its markedly different morphology and behavior compared to the adult form. Larvae often have a distinct appearance, featuring unsegmented bodies, simple sense organs, and undeveloped digestive systems. They are typically adapted for a specific mode of life, such as free-living or parasitic existence, and rely on external sources of nutrition for their development.

In the context of helminth infections, larvae may be transmitted to humans through various routes, including ingestion of contaminated food or water, direct skin contact with infective stages, or transmission via an intermediate host (such as a vector). Once inside the human body, these parasitic larvae can cause tissue damage and provoke immune responses, leading to the clinical manifestations of disease.

It is essential to distinguish between the medical definition of 'larva' and its broader usage in biology and zoology. In those fields, 'larva' refers to any juvenile form that undergoes metamorphosis before reaching adulthood, regardless of whether it is parasitic or not.

Vitellogenins are a group of precursor proteins that are synthesized in the liver and subsequently transported to the ovaries, where they are taken up by developing oocytes. Once inside the oocyte, vitellogenins are cleaved into smaller proteins called lipovitellins and phosvitins, which play a crucial role in providing nutrients and energy to the developing embryo.

Vitellogenins are found in many oviparous species, including birds, reptiles, amphibians, fish, and some invertebrates. They are typically composed of several domains, including a large N-terminal domain that is rich in acidic amino acids, a central von Willebrand factor type D domain, and a C-terminal domain that contains multiple repeat units.

In addition to their role in egg development, vitellogenins have also been implicated in various physiological processes, such as immune function, stress response, and metal homeostasis. Moreover, the levels of vitellogenin in the blood can serve as a biomarker for environmental exposure to estrogenic compounds, as these chemicals can induce the synthesis of vitellogenins in male and juvenile animals.

Vitellins are a group of precursor proteins found in the yolk of eggs of many animals, including birds and reptiles. They play a crucial role in the development of the embryo by providing it with essential nutrients, such as amino acids, lipids, and carbohydrates. Vitellins are synthesized in the liver of the female animal and then transported to the ovaries, where they are stored in the yolk granules of developing eggs. During embryonic development, vitellins are broken down into smaller peptides and free amino acids, which can be easily absorbed and utilized by the growing embryo.

In a medical context, vitellins may be studied in relation to reproductive biology, nutrition, and developmental biology. However, they do not have direct clinical relevance to human health or disease, as humans do not produce eggs with yolks containing vitellins.

Hormones are defined as chemical messengers that are produced by endocrine glands or specialized cells and are transported through the bloodstream to tissues and organs, where they elicit specific responses. They play crucial roles in regulating various physiological processes such as growth, development, metabolism, reproduction, and mood. Examples of hormones include insulin, estrogen, testosterone, adrenaline, and thyroxine.

I believe there may be some confusion in your question. "Moths" are not a medical term, but rather they are a group of insects closely related to butterflies. They belong to the order Lepidoptera and are characterized by their scales covering their wings and body. If you have any questions about moths or if you meant to ask something else, please let me know!

Carboxylic ester hydrolases are a class of enzymes that catalyze the hydrolysis of ester bonds in carboxylic acid esters, producing alcohols and carboxylates. This group includes several subclasses of enzymes such as esterases, lipases, and thioesterases. These enzymes play important roles in various biological processes, including metabolism, detoxification, and signal transduction. They are widely used in industrial applications, such as the production of biodiesel, pharmaceuticals, and food ingredients.

"Manduca" is not a term commonly used in medical definitions. However, it does refer to a genus of moths, also known as the "hawk moths." While there are no direct medical applications or definitions associated with this term, it's worth noting that some species of hawk moths have been used in scientific research. For instance, the tobacco hornworm (Manduca sexta) is a popular model organism for studying insect physiology and genetics.

In a broader context, understanding the biology and behavior of Manduca can contribute to fields like ecology, entomology, and environmental science, which in turn can have indirect implications for human health, agriculture, and conservation. However, it is not a term that would be used in a medical context for diagnosing or treating diseases.

I'm sorry for any confusion, but "Lepidoptera" is not a medical term. It is a taxonomic order that includes moths and butterflies, which are insects known for their distinctive wing scales. This term is used in the field of biology, not medicine.

Ecdysone is a steroid hormone that triggers molting in arthropods, including insects. It's responsible for the regulation of growth and development in these organisms. When ecdysone binds to specific receptors within the cell, it initiates a cascade of events leading to the shedding of the old exoskeleton and the formation of a new one. This process is essential for the growth and survival of arthropods, as their rigid exoskeletons do not allow for expansion. By understanding ecdysone and its role in insect development, researchers can develop targeted strategies to control pest insect populations.

"Bees" are not a medical term, as they refer to various flying insects belonging to the Apidae family in the Apoidea superfamily. They are known for their role in pollination and honey production. If you're looking for medical definitions or information, please provide relevant terms.

"Tribolium" is not a term commonly used in medical definitions. It is actually the name of a genus of beetles, also known as flour beetles, which are often used in scientific research, particularly in the fields of genetics and evolution. If you have any confusion with a specific medical context where this term was used, I would recommend checking the source again for clarification.

Thyroid hormones are hormones produced and released by the thyroid gland, a small endocrine gland located in the neck that helps regulate metabolism, growth, and development in the human body. The two main thyroid hormones are triiodothyronine (T3) and thyroxine (T4), which contain iodine atoms. These hormones play a crucial role in various bodily functions, including heart rate, body temperature, digestion, and brain development. They help regulate the rate at which your body uses energy, affects how sensitive your body is to other hormones, and plays a vital role in the development and differentiation of all cells of the human body. Thyroid hormone levels are regulated by the hypothalamus and pituitary gland through a feedback mechanism that helps maintain proper balance.

"Bombyx" is a genus name that refers to a group of insects in the family Bombycidae, which are known as silk moths. The most well-known species in this genus is "Bombyx mori," which is the domesticated silkworm used for commercial silk production.

The term "Bombyx" itself does not have a specific medical definition, but it is sometimes used in medical or scientific contexts to refer to this group of insects or their characteristics. For example, researchers might study the effects of Bombyx mori silk on wound healing or tissue regeneration.

It's worth noting that while some species of moths and butterflies can be harmful to human health in certain circumstances (such as by acting as vectors for diseases), the Bombyx genus is not typically considered a medical concern.

Sesquiterpenes are a class of terpenes that consist of three isoprene units, hence the name "sesqui-" meaning "one and a half" in Latin. They are composed of 15 carbon atoms and have a wide range of chemical structures and biological activities. Sesquiterpenes can be found in various plants, fungi, and insects, and they play important roles in the defense mechanisms of these organisms. Some sesquiterpenes are also used in traditional medicine and have been studied for their potential therapeutic benefits.

Farnesol is a chemical compound classified as a sesquiterpene alcohol. It is produced by various plants and insects, including certain types of roses and citrus fruits, and plays a role in their natural defense mechanisms. Farnesol has a variety of uses in the perfume industry due to its pleasant, floral scent.

In addition to its natural occurrence, farnesol is also synthetically produced for use in various applications, including as a fragrance ingredient and as an antimicrobial agent in cosmetics and personal care products. It has been shown to have antibacterial and antifungal properties, making it useful for preventing the growth of microorganisms in these products.

Farnesol is not typically used as a medication or therapeutic agent in humans, but it may have potential uses in the treatment of certain medical conditions due to its antimicrobial and anti-inflammatory properties. However, more research is needed to fully understand its effects and safety profile in these contexts.

Follicle-Stimulating Hormone (FSH) is a glycoprotein hormone secreted and released by the anterior pituitary gland. In females, it promotes the growth and development of ovarian follicles in the ovary, which ultimately leads to the maturation and release of an egg (ovulation). In males, FSH stimulates the testes to produce sperm. It works in conjunction with luteinizing hormone (LH) to regulate reproductive processes. The secretion of FSH is controlled by the hypothalamic-pituitary-gonadal axis and its release is influenced by the levels of gonadotropin-releasing hormone (GnRH), estrogen, inhibin, and androgens.

Insect hormones are chemical messengers that regulate various physiological and behavioral processes in insects. They are produced and released by endocrine glands and organs, such as the corpora allata, prothoracic glands, and neurosecretory cells located in the brain. Insect hormones play crucial roles in the regulation of growth and development, reproduction, diapause (a state of dormancy), metamorphosis, molting, and other vital functions. Some well-known insect hormones include juvenile hormone (JH), ecdysteroids (such as 20-hydroxyecdysone), and neuropeptides like the brain hormone and adipokinetic hormone. These hormones act through specific receptors, often transmembrane proteins, to elicit intracellular signaling cascades that ultimately lead to changes in gene expression, cell behavior, or organ function. Understanding insect hormones is essential for developing novel strategies for pest management and control, as well as for advancing our knowledge of insect biology and evolution.

Luteinizing Hormone (LH) is a glycoprotein hormone, which is primarily produced and released by the anterior pituitary gland. In women, a surge of LH triggers ovulation, the release of an egg from the ovaries during the menstrual cycle. During pregnancy, LH stimulates the corpus luteum to produce progesterone. In men, LH stimulates the testes to produce testosterone. It plays a crucial role in sexual development, reproduction, and maintaining the reproductive system.

"Tenebrio" is the genus name for mealworm beetles, which are insects commonly found in stored grains and animal feed. The most common species is Tenebrio molitor. Mealworms and their larvae are often used as a food source for pets, such as reptiles and birds, but they can also cause damage to crops and structures if they infest them. They have been studied in various medical and scientific research fields including nutrition, toxicology, and allergies. Some people may have allergic reactions to mealworms or their byproducts.

I apologize for any confusion, but "insects" are not a medical term. Insects are small air-breathing arthropods that have a segmented body with six legs and usually have wings. They make up the largest group of animals on Earth, with over a million described species.

If you're looking for information about a specific medical condition or topic, please provide more details so I can offer a relevant response.

'Cyperus' is a genus of plants in the family Cyperaceae, also known as the sedge family. These plants are typically found in wet or moist environments and are characterized by their triangular stems and narrow, grass-like leaves. Some common species of *Cyperus* include *C. alternifolius* (alternanthera), *C. papyrus* (paper reed), and *C. rotundus* (nutgrass). While some species of *Cyperus* have medicinal uses, there is no single medical definition for the genus as a whole.

Genes in insects refer to the hereditary units of DNA that are passed down from parents to offspring and contain the instructions for the development, function, and reproduction of an organism. These genetic materials are located within the chromosomes in the nucleus of insect cells. They play a crucial role in determining various traits such as physical characteristics, behavior, and susceptibility to diseases.

Insect genes, like those of other organisms, consist of exons (coding regions) that contain information for protein synthesis and introns (non-coding regions) that are removed during the process of gene expression. The expression of insect genes is regulated by various factors such as transcription factors, enhancers, and silencers, which bind to specific DNA sequences to activate or repress gene transcription.

Understanding the genetic makeup of insects has important implications for various fields, including agriculture, public health, and evolutionary biology. For example, genes associated with insect pests' resistance to pesticides can be identified and targeted to develop more effective control strategies. Similarly, genes involved in disease transmission by insect vectors such as mosquitoes can be studied to develop novel interventions for preventing the spread of infectious diseases.

Parathyroid hormone (PTH) is a polypeptide hormone that plays a crucial role in the regulation of calcium and phosphate levels in the body. It is produced and secreted by the parathyroid glands, which are four small endocrine glands located on the back surface of the thyroid gland.

The primary function of PTH is to maintain normal calcium levels in the blood by increasing calcium absorption from the gut, mobilizing calcium from bones, and decreasing calcium excretion by the kidneys. PTH also increases phosphate excretion by the kidneys, which helps to lower serum phosphate levels.

In addition to its role in calcium and phosphate homeostasis, PTH has been shown to have anabolic effects on bone tissue, stimulating bone formation and preventing bone loss. However, chronic elevations in PTH levels can lead to excessive bone resorption and osteoporosis.

Overall, Parathyroid Hormone is a critical hormone that helps maintain mineral homeostasis and supports healthy bone metabolism.

Invertebrate hormones refer to the chemical messengers that regulate various physiological processes in invertebrate animals, which include insects, mollusks, worms, and other animals without a backbone. These hormones are produced by specialized endocrine cells or glands and released into the bloodstream to target organs, where they elicit specific responses that help control growth, development, reproduction, metabolism, and behavior.

Examples of invertebrate hormones include:

1. Ecdysteroids: These are steroid hormones found in arthropods such as insects and crustaceans. They regulate molting (ecdysis) and metamorphosis by stimulating the growth and differentiation of new cuticle layers.
2. Juvenile hormone (JH): This is a sesquiterpenoid hormone produced by the corpora allata glands in insects. JH plays a crucial role in maintaining the juvenile stage, regulating reproduction, and controlling diapause (a period of suspended development during unfavorable conditions).
3. Neuropeptides: These are short chains of amino acids that act as hormones or neurotransmitters in invertebrates. They regulate various functions such as feeding behavior, growth, reproduction, and circadian rhythms. Examples include the neuropeptide F (NPF), which controls food intake and energy balance, and the insulin-like peptides (ILPs) that modulate metabolism and growth.
4. Molluscan cardioactive peptides: These are neuropeptides found in mollusks that regulate heart function by controlling heart rate and contractility. An example is FMRFamide, which has been identified in various mollusk species and influences several physiological processes, including feeding behavior, muscle contraction, and reproduction.
5. Vertebrate-like hormones: Some invertebrates produce hormones that are structurally and functionally similar to those found in vertebrates. For example, some annelids (segmented worms) and cephalopods (squid and octopus) have insulin-like peptides that regulate metabolism and growth, while certain echinoderms (starfish and sea urchins) produce steroid hormones that control reproduction.

In summary, invertebrates utilize various types of hormones to regulate their physiological functions, including neuropeptides, cardioactive peptides, insulin-like peptides, and vertebrate-like hormones. These hormones play crucial roles in controlling growth, development, reproduction, feeding behavior, and other essential processes that maintain homeostasis and ensure survival. Understanding the mechanisms of hormone action in invertebrates can provide valuable insights into the evolution of hormonal systems and their functions across different animal taxa.

"Aedes" is a genus of mosquitoes that are known to transmit various diseases, including Zika virus, dengue fever, chikungunya, and yellow fever. These mosquitoes are typically found in tropical and subtropical regions around the world. They are distinguished by their black and white striped legs and thorax. Aedes aegypti is the most common species associated with disease transmission, although other species such as Aedes albopictus can also transmit diseases. It's important to note that only female mosquitoes bite and feed on blood, while males feed solely on nectar and plant juices.

Gonadotropin-Releasing Hormone (GnRH), also known as Luteinizing Hormone-Releasing Hormone (LHRH), is a hormonal peptide consisting of 10 amino acids. It is produced and released by the hypothalamus, an area in the brain that links the nervous system to the endocrine system via the pituitary gland.

GnRH plays a crucial role in regulating reproduction and sexual development through its control of two gonadotropins: follicle-stimulating hormone (FSH) and luteinizing hormone (LH). These gonadotropins, in turn, stimulate the gonads (ovaries or testes) to produce sex steroids and eggs or sperm.

GnRH acts on the anterior pituitary gland by binding to its specific receptors, leading to the release of FSH and LH. The hypothalamic-pituitary-gonadal axis is under negative feedback control, meaning that when sex steroid levels are high, they inhibit the release of GnRH, which subsequently decreases FSH and LH secretion.

GnRH agonists and antagonists have clinical applications in various medical conditions, such as infertility treatments, precocious puberty, endometriosis, uterine fibroids, prostate cancer, and hormone-responsive breast cancer.

Gonadal steroid hormones, also known as gonadal sex steroids, are hormones that are produced and released by the gonads (i.e., ovaries in women and testes in men). These hormones play a critical role in the development and maintenance of secondary sexual characteristics, reproductive function, and overall health.

The three main classes of gonadal steroid hormones are:

1. Androgens: These are male sex hormones that are primarily produced by the testes but also produced in smaller amounts by the ovaries and adrenal glands. The most well-known androgen is testosterone, which plays a key role in the development of male secondary sexual characteristics such as facial hair, deepening of the voice, and increased muscle mass.
2. Estrogens: These are female sex hormones that are primarily produced by the ovaries but also produced in smaller amounts by the adrenal glands. The most well-known estrogen is estradiol, which plays a key role in the development of female secondary sexual characteristics such as breast development and the menstrual cycle.
3. Progestogens: These are hormones that are produced by the ovaries during the second half of the menstrual cycle and play a key role in preparing the uterus for pregnancy. The most well-known progestogen is progesterone, which also plays a role in maintaining pregnancy and regulating the menstrual cycle.

Gonadal steroid hormones can have significant effects on various physiological processes, including bone density, cognitive function, mood, and sexual behavior. Disorders of gonadal steroid hormone production or action can lead to a range of health problems, including infertility, osteoporosis, and sexual dysfunction.

'Drosophila melanogaster' is the scientific name for a species of fruit fly that is commonly used as a model organism in various fields of biological research, including genetics, developmental biology, and evolutionary biology. Its small size, short generation time, large number of offspring, and ease of cultivation make it an ideal subject for laboratory studies. The fruit fly's genome has been fully sequenced, and many of its genes have counterparts in the human genome, which facilitates the understanding of genetic mechanisms and their role in human health and disease.

Here is a brief medical definition:

Drosophila melanogaster (droh-suh-fih-luh meh-lon-guh-ster): A species of fruit fly used extensively as a model organism in genetic, developmental, and evolutionary research. Its genome has been sequenced, revealing many genes with human counterparts, making it valuable for understanding genetic mechanisms and their role in human health and disease.

Reproduction, in the context of biology and medicine, refers to the process by which organisms produce offspring. It is a complex process that involves the creation, development, and growth of new individuals from parent organisms. In sexual reproduction, this process typically involves the combination of genetic material from two parents through the fusion of gametes (sex cells) such as sperm and egg cells. This results in the formation of a zygote, which then develops into a new individual with a unique genetic makeup.

In contrast, asexual reproduction does not involve the fusion of gametes and can occur through various mechanisms such as budding, fragmentation, or parthenogenesis. Asexual reproduction results in offspring that are genetically identical to the parent organism.

Reproduction is a fundamental process that ensures the survival and continuation of species over time. It is also an area of active research in fields such as reproductive medicine, where scientists and clinicians work to understand and address issues related to human fertility, contraception, and genetic disorders.

I'm sorry for any confusion, but "grasshoppers" is not a term used in medical definitions. Grasshoppers are a type of insect that belongs to the order Orthoptera and suborder Caelifera. They are known for their long hind legs which they use for jumping, and some species can jump over 20 times their own body length. If you have any questions about medical terminology or topics, I'd be happy to help with those instead!

Decapitation is the surgical separation or removal of the head from the body. It is also used to describe the traumatic separation of the head from the body, such as in a severe accident or a violent act. In a medical context, decapitation may be performed during an autopsy or as part of a surgical procedure for certain conditions like cancer or severe trauma.

'Isoptera' is an outdated term for a taxonomic order of social insects commonly known as termites. These eusocial insects are closely related to cockroaches and share some similarities in their appearance, but they have specialized castes including workers, soldiers, and reproductives that live in colonies. Termites feed on wood, plant fibers, and other materials containing cellulose, which they break down with the help of symbiotic protozoa living in their gut. The order Isoptera is no longer recognized by modern taxonomists, who now place termites within the cockroach family Blattodea.

I'm sorry for any confusion, but "Nymph" does not have a medical definition. In general, nymph is a term used in mythology to refer to a minor nature deity typically represented as an attractive maiden or beautiful young woman who animates nature and is often associated with various natural phenomena.

If you have any medical concerns or questions, I would be happy to help if you could provide more information.

Endocrine glands are ductless glands in the human body that release hormones directly into the bloodstream, which then carry the hormones to various tissues and organs in the body. These glands play a crucial role in regulating many of the body's functions, including metabolism, growth and development, tissue function, sexual function, reproduction, sleep, and mood.

Examples of endocrine glands include the pituitary gland, thyroid gland, parathyroid glands, adrenal glands, pineal gland, pancreas, ovaries, and testes. Each of these glands produces specific hormones that have unique effects on various target tissues in the body.

The endocrine system works closely with the nervous system to regulate many bodily functions through a complex network of feedback mechanisms. Disorders of the endocrine system can result in a wide range of symptoms and health problems, including diabetes, thyroid disease, growth disorders, and sexual dysfunction.

"Gryllidae" is not a medical term. It is the family designation for crickets in the order Orthoptera, which includes various species of insects that are characterized by their long antennae and ability to produce chirping sounds. The misinterpretation might have arisen from the fact that some scientific research or studies may reference these creatures; however, it is not a medical term or concept.

Molecular sequence data refers to the specific arrangement of molecules, most commonly nucleotides in DNA or RNA, or amino acids in proteins, that make up a biological macromolecule. This data is generated through laboratory techniques such as sequencing, and provides information about the exact order of the constituent molecules. This data is crucial in various fields of biology, including genetics, evolution, and molecular biology, allowing for comparisons between different organisms, identification of genetic variations, and studies of gene function and regulation.

Blattellidae is a family of small to medium-sized insects commonly known as cockroaches or wood cockroaches. They are closely related to the larger Blaberidae family, which includes many of the tropical cockroaches. Blattellidae species are found worldwide and include some of the most common and widespread cockroaches, such as the German cockroach (Blattella germanica) and the brown-banded cockroach (Supella longipalpa).

These insects are generally small, with adults ranging in size from about 1/2 to 3/4 inch (1.2 to 1.9 centimeters) in length. They have a flattened body and long, slender antennae. The wings of Blattellidae species are well-developed, but they are not strong flyers. Instead, they tend to scuttle quickly away when disturbed.

Blattellidae cockroaches are omnivorous, feeding on a wide variety of plant and animal materials. They can be found in a range of habitats, including forests, grasslands, and urban environments. Some species are adapted to living in close association with humans and can be found in homes, restaurants, and other buildings.

Like all cockroaches, Blattellidae species have the potential to carry and transmit diseases, as well as cause allergic reactions in some people. It is important to take steps to prevent and control infestations of these pests in order to maintain a healthy living environment.

Thyroid hormone receptors (THRs) are nuclear receptor proteins that bind to thyroid hormones, triiodothyronine (T3) and thyroxine (T4), and regulate gene transcription in target cells. These receptors play a crucial role in the development, growth, and metabolism of an organism by mediating the actions of thyroid hormones. THRs are encoded by genes THRA and THRB, which give rise to two major isoforms: TRα1 and TRβ1. Additionally, alternative splicing results in other isoforms with distinct tissue distributions and functions. THRs function as heterodimers with retinoid X receptors (RXRs) and bind to thyroid hormone response elements (TREs) in the regulatory regions of target genes. The binding of T3 or T4 to THRs triggers a conformational change, which leads to recruitment of coactivators or corepressors, ultimately resulting in activation or repression of gene transcription.

Acetone is a colorless, volatile, and flammable liquid organic compound with the chemical formula (CH3)2CO. It is the simplest and smallest ketone, and its molecules consist of a carbonyl group linked to two methyl groups. Acetone occurs naturally in the human body and is produced as a byproduct of normal metabolic processes, particularly during fat burning.

In clinical settings, acetone can be measured in breath or blood to assess metabolic status, such as in cases of diabetic ketoacidosis, where an excess production of acetone and other ketones occurs due to insulin deficiency and high levels of fatty acid breakdown. High concentrations of acetone can lead to a sweet, fruity odor on the breath, often described as "fruity acetone" or "acetone breath."

Human Growth Hormone (HGH), also known as somatotropin, is a peptide hormone produced in the pituitary gland. It plays a crucial role in human development and growth by stimulating the production of another hormone called insulin-like growth factor 1 (IGF-1). IGF-1 promotes the growth and reproduction of cells throughout the body, particularly in bones and other tissues. HGH also helps regulate body composition, body fluids, muscle and bone growth, sugar and fat metabolism, and possibly heart function. It is essential for human development and continues to have important effects throughout life. The secretion of HGH decreases with age, which is thought to contribute to the aging process.

Diazonium compounds are a class of organic compounds that contain the functional group -N=N+E-, where E- represents a halide ion or an organic cation. They are typically prepared by treating an aromatic primary amine with nitrous acid (HNO2) in an acidic medium, which results in the formation of a diazonium ion.

The general reaction can be represented as follows:

R-NH2 + HNO2 + HX → R-N=N+X- + 2H2O

where R represents the aromatic ring and X- is a halide ion (Cl-, Br-, or I-).

Diazonium compounds are important intermediates in organic synthesis, particularly in the preparation of azo dyes and other colored compounds. They are also useful for introducing functional groups into aromatic rings through various chemical reactions such as sandmeyer reaction, gattermann reaction etc. However, diazonium salts are generally unstable and can decompose explosively if heated or subjected to strong shock or friction. Therefore, they must be handled with care.

Oviposition is a medical/biological term that refers to the process of laying or depositing eggs by female organisms, including birds, reptiles, insects, and fish. In humans and other mammals, the term is not applicable since they give birth to live young rather than laying eggs.

Adrenocorticotropic Hormone (ACTH) is a hormone produced and released by the anterior pituitary gland, a small endocrine gland located at the base of the brain. ACTH plays a crucial role in the regulation of the body's stress response and has significant effects on various physiological processes.

The primary function of ACTH is to stimulate the adrenal glands, which are triangular-shaped glands situated on top of the kidneys. The adrenal glands consist of two parts: the outer cortex and the inner medulla. ACTH specifically targets the adrenal cortex, where it binds to specific receptors and initiates a series of biochemical reactions leading to the production and release of steroid hormones, primarily cortisol (a glucocorticoid) and aldosterone (a mineralocorticoid).

Cortisol is involved in various metabolic processes, such as regulating blood sugar levels, modulating the immune response, and helping the body respond to stress. Aldosterone plays a vital role in maintaining electrolyte and fluid balance by promoting sodium reabsorption and potassium excretion in the kidneys.

ACTH release is controlled by the hypothalamus, another part of the brain, which produces corticotropin-releasing hormone (CRH). CRH stimulates the anterior pituitary gland to secrete ACTH, which in turn triggers cortisol production in the adrenal glands. This complex feedback system helps maintain homeostasis and ensures that appropriate amounts of cortisol are released in response to various physiological and psychological stressors.

Disorders related to ACTH can lead to hormonal imbalances, resulting in conditions such as Cushing's syndrome (excessive cortisol production) or Addison's disease (insufficient cortisol production). Proper diagnosis and management of these disorders typically involve assessing the function of the hypothalamic-pituitary-adrenal axis and addressing any underlying issues affecting ACTH secretion.

Diptera is an order of insects that includes flies, mosquitoes, and gnats. The name "Diptera" comes from the Greek words "di," meaning two, and "pteron," meaning wing. This refers to the fact that all members of this order have a single pair of functional wings for flying, while the other pair is reduced to small knob-like structures called halteres, which help with balance and maneuverability during flight.

Some common examples of Diptera include houseflies, fruit flies, horseflies, tsetse flies, and midges. Many species in this order are important pollinators, while others can be significant pests or disease vectors. The study of Diptera is called dipterology.

'Animal structures' is a broad term that refers to the various physical parts and organs that make up animals. These structures can include everything from the external features, such as skin, hair, and scales, to the internal organs and systems, such as the heart, lungs, brain, and digestive system.

Animal structures are designed to perform specific functions that enable the animal to survive, grow, and reproduce. For example, the heart pumps blood throughout the body, delivering oxygen and nutrients to the cells, while the lungs facilitate gas exchange between the animal and its environment. The brain serves as the control center of the nervous system, processing sensory information and coordinating motor responses.

Animal structures can be categorized into different systems based on their function, such as the circulatory system, respiratory system, nervous system, digestive system, and reproductive system. Each system is made up of various structures that work together to perform a specific function.

Understanding animal structures and how they function is essential for understanding animal biology and behavior. It also has important implications for human health, as many animals serve as models for studying human disease and developing new treatments.

Heteroptera is not a medical term, but a taxonomic category in zoology. It refers to a suborder of insects within the order Hemiptera, also known as true bugs. This group includes a wide variety of species, such as bed bugs, assassin bugs, and stink bugs. While Heteroptera is not directly related to human health or medicine, some species can have medical importance as disease vectors or pests.

Developmental gene expression regulation refers to the processes that control the activation or repression of specific genes during embryonic and fetal development. These regulatory mechanisms ensure that genes are expressed at the right time, in the right cells, and at appropriate levels to guide proper growth, differentiation, and morphogenesis of an organism.

Developmental gene expression regulation is a complex and dynamic process involving various molecular players, such as transcription factors, chromatin modifiers, non-coding RNAs, and signaling molecules. These regulators can interact with cis-regulatory elements, like enhancers and promoters, to fine-tune the spatiotemporal patterns of gene expression during development.

Dysregulation of developmental gene expression can lead to various congenital disorders and developmental abnormalities. Therefore, understanding the principles and mechanisms governing developmental gene expression regulation is crucial for uncovering the etiology of developmental diseases and devising potential therapeutic strategies.

"Molting" is not a term typically used in medical contexts. It is primarily used to describe the shedding and replacement of feathers, hair, or skin in animals, including birds, reptiles, insects, and other invertebrates. In humans and other mammals, this process is more commonly referred to as "shedding" or "growing new hair/skin."

However, if you are referring to the medical term "molt," it is a rare genetic disorder that affects the skin's pigmentation and causes it to shed in patches. It is also known as "congenital ichthyosiform erythroderma" or "non-bullous congenital ichthyosiform erythroderma." The condition is present at birth, and affected individuals have red, scaly skin that sheds in a pattern similar to snake skin. Molting is not contagious and has no known cure, but various treatments can help manage its symptoms.

I could not find a widely accepted medical definition for "sex attractants" as it is not a standard term used in medical literature. However, the concept of sex attractants is often discussed in the context of animal behavior and can refer to chemical substances that animals produce and release to attract mates. These substances are also known as pheromones.

In humans, there is ongoing scientific debate about whether or not pheromones play a significant role in sexual attraction and mate selection. Some studies suggest that humans may have a functional vomeronasal organ (VNO), which is involved in the detection of pheromones in other animals. However, many scientists remain skeptical about the role of human sex attractants or pheromones due to limited evidence and conflicting results from various studies.

Therefore, it's essential to note that while there may be some scientific interest in the concept of human sex attractants, it is not a well-established area of study within medical research.

Pituitary hormones are chemical messengers produced and released by the pituitary gland, a small endocrine gland located at the base of the brain. The pituitary gland is often referred to as the "master gland" because it controls several other endocrine glands and regulates various bodily functions.

There are two main types of pituitary hormones: anterior pituitary hormones and posterior pituitary hormones, which are produced in different parts of the pituitary gland and have distinct functions.

Anterior pituitary hormones include:

1. Growth hormone (GH): regulates growth and metabolism.
2. Thyroid-stimulating hormone (TSH): stimulates the thyroid gland to produce thyroid hormones.
3. Adrenocorticotropic hormone (ACTH): stimulates the adrenal glands to produce cortisol and other steroid hormones.
4. Follicle-stimulating hormone (FSH) and luteinizing hormone (LH): regulate reproductive function in both males and females.
5. Prolactin: stimulates milk production in lactating women.
6. Melanocyte-stimulating hormone (MSH): regulates skin pigmentation and appetite.

Posterior pituitary hormones include:

1. Oxytocin: stimulates uterine contractions during childbirth and milk ejection during lactation.
2. Vasopressin (antidiuretic hormone, ADH): regulates water balance in the body by controlling urine production in the kidneys.

Overall, pituitary hormones play crucial roles in regulating growth, development, metabolism, reproductive function, and various other bodily functions. Abnormalities in pituitary hormone levels can lead to a range of medical conditions, such as dwarfism, acromegaly, Cushing's disease, infertility, and diabetes insipidus.

"Butterflies" is not a medical term, but rather a colloquial or informal term that is often used to describe a feeling of nervousness or excitement in the stomach. It is thought to be due to the release of adrenaline and the increased heart rate and breathing that can occur when someone is anxious or excited. The sensation may be caused by the contraction of the muscles in the stomach, which can feel like fluttering or flips. This feeling is not a medical condition and does not typically require treatment, but if it is severe or persistent, it may be helpful to speak with a healthcare provider to address any underlying anxiety or stress.

Messenger RNA (mRNA) is a type of RNA (ribonucleic acid) that carries genetic information copied from DNA in the form of a series of three-base code "words," each of which specifies a particular amino acid. This information is used by the cell's machinery to construct proteins, a process known as translation. After being transcribed from DNA, mRNA travels out of the nucleus to the ribosomes in the cytoplasm where protein synthesis occurs. Once the protein has been synthesized, the mRNA may be degraded and recycled. Post-transcriptional modifications can also occur to mRNA, such as alternative splicing and addition of a 5' cap and a poly(A) tail, which can affect its stability, localization, and translation efficiency.

An amino acid sequence is the specific order of amino acids in a protein or peptide molecule, formed by the linking of the amino group (-NH2) of one amino acid to the carboxyl group (-COOH) of another amino acid through a peptide bond. The sequence is determined by the genetic code and is unique to each type of protein or peptide. It plays a crucial role in determining the three-dimensional structure and function of proteins.

An ovary is a part of the female reproductive system in which ova or eggs are produced through the process of oogenesis. They are a pair of solid, almond-shaped structures located one on each side of the uterus within the pelvic cavity. Each ovary measures about 3 to 5 centimeters in length and weighs around 14 grams.

The ovaries have two main functions: endocrine (hormonal) function and reproductive function. They produce and release eggs (ovulation) responsible for potential fertilization and development of an embryo/fetus during pregnancy. Additionally, they are essential in the production of female sex hormones, primarily estrogen and progesterone, which regulate menstrual cycles, sexual development, and reproduction.

During each menstrual cycle, a mature egg is released from one of the ovaries into the fallopian tube, where it may be fertilized by sperm. If not fertilized, the egg, along with the uterine lining, will be shed, leading to menstruation.

"Beetles" is not a medical term. It is a common name used to refer to insects belonging to the order Coleoptera, which is one of the largest orders in the class Insecta. Beetles are characterized by their hardened forewings, known as elytra, which protect their hind wings and body when not in use for flying.

There are many different species of beetles found all over the world, and some can have an impact on human health. For example, certain types of beetles, such as bed bugs and carpet beetles, can cause skin irritation and allergic reactions in some people. Other beetles, like the Colorado potato beetle, can damage crops and lead to economic losses for farmers. However, it is important to note that most beetles are not harmful to humans and play an essential role in ecosystems as decomposers and pollinators.

A base sequence in the context of molecular biology refers to the specific order of nucleotides in a DNA or RNA molecule. In DNA, these nucleotides are adenine (A), guanine (G), cytosine (C), and thymine (T). In RNA, uracil (U) takes the place of thymine. The base sequence contains genetic information that is transcribed into RNA and ultimately translated into proteins. It is the exact order of these bases that determines the genetic code and thus the function of the DNA or RNA molecule.

'Drosophila proteins' refer to the proteins that are expressed in the fruit fly, Drosophila melanogaster. This organism is a widely used model system in genetics, developmental biology, and molecular biology research. The study of Drosophila proteins has contributed significantly to our understanding of various biological processes, including gene regulation, cell signaling, development, and aging.

Some examples of well-studied Drosophila proteins include:

1. HSP70 (Heat Shock Protein 70): A chaperone protein involved in protein folding and protection from stress conditions.
2. TUBULIN: A structural protein that forms microtubules, important for cell division and intracellular transport.
3. ACTIN: A cytoskeletal protein involved in muscle contraction, cell motility, and maintenance of cell shape.
4. BETA-GALACTOSIDASE (LACZ): A reporter protein often used to monitor gene expression patterns in transgenic flies.
5. ENDOGLIN: A protein involved in the development of blood vessels during embryogenesis.
6. P53: A tumor suppressor protein that plays a crucial role in preventing cancer by regulating cell growth and division.
7. JUN-KINASE (JNK): A signaling protein involved in stress response, apoptosis, and developmental processes.
8. DECAPENTAPLEGIC (DPP): A member of the TGF-β (Transforming Growth Factor Beta) superfamily, playing essential roles in embryonic development and tissue homeostasis.

These proteins are often studied using various techniques such as biochemistry, genetics, molecular biology, and structural biology to understand their functions, interactions, and regulation within the cell.

Neuropeptides are small protein-like molecules that are used by neurons to communicate with each other and with other cells in the body. They are produced in the cell body of a neuron, processed from larger precursor proteins, and then transported to the nerve terminal where they are stored in secretory vesicles. When the neuron is stimulated, the vesicles fuse with the cell membrane and release their contents into the extracellular space.

Neuropeptides can act as neurotransmitters or neuromodulators, depending on their target receptors and the duration of their effects. They play important roles in a variety of physiological processes, including pain perception, appetite regulation, stress response, and social behavior. Some neuropeptides also have hormonal functions, such as oxytocin and vasopressin, which are produced in the hypothalamus and released into the bloodstream to regulate reproductive and cardiovascular function, respectively.

There are hundreds of different neuropeptides that have been identified in the nervous system, and many of them have multiple functions and interact with other signaling molecules to modulate neural activity. Dysregulation of neuropeptide systems has been implicated in various neurological and psychiatric disorders, such as chronic pain, addiction, depression, and anxiety.

Triiodothyronine (T3) is a thyroid hormone, specifically the active form of thyroid hormone, that plays a critical role in the regulation of metabolism, growth, and development in the human body. It is produced by the thyroid gland through the iodination and coupling of the amino acid tyrosine with three atoms of iodine. T3 is more potent than its precursor, thyroxine (T4), which has four iodine atoms, as T3 binds more strongly to thyroid hormone receptors and accelerates metabolic processes at the cellular level.

In circulation, about 80% of T3 is bound to plasma proteins, while the remaining 20% is unbound or free, allowing it to enter cells and exert its biological effects. The primary functions of T3 include increasing the rate of metabolic reactions, promoting protein synthesis, enhancing sensitivity to catecholamines (e.g., adrenaline), and supporting normal brain development during fetal growth and early infancy. Imbalances in T3 levels can lead to various medical conditions, such as hypothyroidism or hyperthyroidism, which may require clinical intervention and management.

Molecular cloning is a laboratory technique used to create multiple copies of a specific DNA sequence. This process involves several steps:

1. Isolation: The first step in molecular cloning is to isolate the DNA sequence of interest from the rest of the genomic DNA. This can be done using various methods such as PCR (polymerase chain reaction), restriction enzymes, or hybridization.
2. Vector construction: Once the DNA sequence of interest has been isolated, it must be inserted into a vector, which is a small circular DNA molecule that can replicate independently in a host cell. Common vectors used in molecular cloning include plasmids and phages.
3. Transformation: The constructed vector is then introduced into a host cell, usually a bacterial or yeast cell, through a process called transformation. This can be done using various methods such as electroporation or chemical transformation.
4. Selection: After transformation, the host cells are grown in selective media that allow only those cells containing the vector to grow. This ensures that the DNA sequence of interest has been successfully cloned into the vector.
5. Amplification: Once the host cells have been selected, they can be grown in large quantities to amplify the number of copies of the cloned DNA sequence.

Molecular cloning is a powerful tool in molecular biology and has numerous applications, including the production of recombinant proteins, gene therapy, functional analysis of genes, and genetic engineering.

Steroid receptors are a type of nuclear receptor protein that are activated by the binding of steroid hormones or related molecules. These receptors play crucial roles in various physiological processes, including development, homeostasis, and metabolism. Steroid receptors function as transcription factors, regulating gene expression when activated by their respective ligands.

There are several subtypes of steroid receptors, classified based on the specific steroid hormones they bind to:

1. Glucocorticoid receptor (GR): Binds to glucocorticoids, which regulate metabolism, immune response, and stress response.
2. Mineralocorticoid receptor (MR): Binds to mineralocorticoids, which regulate electrolyte and fluid balance.
3. Androgen receptor (AR): Binds to androgens, which are male sex hormones that play a role in the development and maintenance of male sexual characteristics.
4. Estrogen receptor (ER): Binds to estrogens, which are female sex hormones that play a role in the development and maintenance of female sexual characteristics.
5. Progesterone receptor (PR): Binds to progesterone, which is a female sex hormone involved in the menstrual cycle and pregnancy.
6. Vitamin D receptor (VDR): Binds to vitamin D, which plays a role in calcium homeostasis and bone metabolism.

Upon ligand binding, steroid receptors undergo conformational changes that allow them to dimerize, interact with co-regulatory proteins, and bind to specific DNA sequences called hormone response elements (HREs) in the promoter regions of target genes. This interaction leads to the recruitment of transcriptional machinery, ultimately resulting in the modulation of gene expression. Dysregulation of steroid receptor signaling has been implicated in various diseases, including cancer, metabolic disorders, and inflammatory conditions.

RNA interference (RNAi) is a biological process in which RNA molecules inhibit the expression of specific genes. This process is mediated by small RNA molecules, including microRNAs (miRNAs) and small interfering RNAs (siRNAs), that bind to complementary sequences on messenger RNA (mRNA) molecules, leading to their degradation or translation inhibition.

RNAi plays a crucial role in regulating gene expression and defending against foreign genetic elements, such as viruses and transposons. It has also emerged as an important tool for studying gene function and developing therapeutic strategies for various diseases, including cancer and viral infections.

Watt, G. R.; Davey, K. G. (1996). "Cellular and Molecular Actions of Juvenile Hormone. II. Roles of Juvenile Hormone in Adult ... JH is principally degraded by the enzymes juvenile-hormone esterase (JHE) or juvenile hormone epoxide hydrolase (JHEH). JHE and ... Juvenile Hormone Sullivan, J. P., Jassim, O., Fahrbach, S. E. and Robinson, G. E. (2000). Juvenile hormone paces behavioral ... "Juvenile Hormone Bisepoxide Biosynthesis in vitro by the Ring Gland of Drosophila melanogaster: A putative juvenile Hormone in ...
... juvenile hormone I + H2O = juvenile hormone I acid + methanol (2) juvenile hormone III + H2O = juvenile hormone III acid + ... Juvenile hormone production, juvenile hormone esterase, and juvenile hormone acid methyltransferase in corpora allata of ... juvenile hormone esterase, and juvenile hormone carboxyesterase. Juvenile hormone (JH) controls insect metamorphosis. High JH ... Metabolism of Cecropia Juvenile Hormone in Insects and in Mammals, in: Menn, J.J., Beroza, M. (Eds.), Insect Juvenile Hormones ...
Juvenile hormone diol is acted on by juvenile hormone diol kinase, to give juvenile hormone diol phosphate, with the phosphate ... Juvenile hormone epoxide hydrolase (JHEH) is an enzyme that inactivates insect juvenile hormones. This inactivation is ... The other is juvenile-hormone esterase, or JHE. The first observation of activity from JHEH was in Rhodnius prolixus and ... In contrast, the juvenile hormone diols that are the product of the epoxide hydrolase are very hydrophilic and cannot be ...
Characterization of the juvenile hormone epoxide hydrolase (JHEH) and juvenile hormone diol phosphotransferase (JHDPT) from ... 1995 Characterization of the juvenile hormone epoxide hydrolase (JHEH) and juvenile hormone diol phosphotransferase (JHDPT) ... and molecular modeling of juvenile hormone-selective diol kinase from Manduca sexta. J. Biol. Chem. 277, 21882-21890 (Hormones) ... Juvenile hormone diol kinase, a calcium-binding protein with kinase activity, from the silkworm, Bombyx mori. Insect Biochem ...
"Aedes aegypti juvenile hormone acid methyl transferase, the ultimate enzyme in the biosynthetic pathway of juvenile hormone III ... Juvenile hormone acid O-methyltransferase (JHAMT) is a ~33 kDa enzyme (the molecular mass is species-dependent) that catalyzes ... Niwa R, Niimi T, Honda N, Yoshiyama M, Itoyama K, Kataoka H, Shinoda T (July 2008). "Juvenile hormone acid O-methyltransferase ... Kinjoh T, Kaneko Y, Itoyama K, Mita K, Hiruma K, Shinoda T (August 2007). "Control of juvenile hormone biosynthesis in Bombyx ...
... family of proteins consists of several insect specific haemolymph juvenile hormone binding proteins. Juvenile hormone (JH) has ... JH is transported from the sites of its synthesis to target tissues by a haemolymph carrier called juvenile hormone-binding ... Kolodziejczyk R, Bujacz G, Jakob M, Ozyhar A, Jaskolski M, Kochman M (March 2008). "Insect juvenile hormone binding protein ... In molecular biology, the haemolymph juvenile hormone-binding protein (JHPB) ...
Devillers, James (2013). Juvenile Hormones and Juvenoids. CRC Press. p. 118. ISBN 978-1-4665-1322-8. Zhang, Jinfa; Fang, Hui; ...
Juvenile hormone regulation of the larval diapause of the Southwestern corn borer, Diatraea grandiosella. C.-M. Yina and G.M. ... Growth and development are regulated by juvenile hormones. The southwestern corn borer has an extensive range. It occurs in ... effects of a juvenile hormone mimic: G. M. Chippendalea1 and C.-M. Yina1a1, Department of Entomology, University of Missouri, ...
The original description of the insect juvenile hormone by Carroll Williams in Nature in 1956 is from the cecropia silkworm. ... This large insect had enough juvenile hormone in its abdomen to permit extraction of detectable amounts from a single specimen ... "The Juvenile Hormone of Insects". Nature. 178 (4526): 212-213. Hultmark D (1982). Insect Immunity: Inducible Antibacterial ...
Meyer, A. S.; H. A. Schneiderman; E. Hanzmann; H. I. Ko (1968). "The two juvenile hormones from the Cecropia silk moth". Proc. ... He helped found the developmental biology center at Case-Western Reserve University where he worked on juvenile hormones and ... was an American entomologist who was a co-discoverer of the insect juvenile hormone II. He worked at several universities ...
Arthropod hormones are present, most notably the juvenile hormone. Trehalose can be present and sometimes in great amounts ... The efficiency of the vertebrate system is far greater than is needed for transporting nutrients, hormones, and so on, whereas ... These sugar levels are maintained by the control of hormones. Other carbohydrates can be present. These include inositol, sugar ...
Devillers, James (2013). Juvenile Hormones and Juvenoids: Modeling Biological Effects and Environmental Fate. CRC Press. p. 39 ... feeds the juveniles for about a month. Crickets are hemimetabolic insects, whose lifecycle consists of an egg stage, a larval ...
The Evolution and Genetics of Migration in Insects Devillers, James (2013). Juvenile Hormones and Juvenoids: Modeling ...
... is a juvenile hormone analog and an insect growth regulator. It prevents larvae from developing into adulthood and ... Devillers, James (May 6, 2013). Juvenile Hormones and Juvenoids: Modeling Biological Effects and Environmental Fate. CRC Press ... "insect development is quite different to human development and involves different hormones, developmental pathways and sets of ...
Pre-mating behaviors and the growth and development of the ovaries are controlled by the juvenile hormone-III, which is ... Hartmann, R; Loher, W; Huber, F. (1994). "Correlation Between the Rate of Juvenile Hormone biosynthesis in Vitro and Sexual ... The production of this juvenile hormone fluctuates. Patterns of behavior are correlated with the increasing or decreasing rate ... The hormone concentration within the hemolymph may be affected by esterases. Corpus allata activity is also affected by ...
Finally, he was active in the field of insect juvenile hormones. Šorm was the author or co-author of a large number of ... He also initiated the study of natural peptides, especially neurohypophyseal hormones and their analogues, some of which were ...
Insect growth regulators (juvenile hormones, chitin synthesis inhibitors, etc.) are available. For example, the insect growth ...
... molt has no juvenile hormone present at all. Experiments on firebugs have shown how juvenile hormone can affect the number of ... molts between larval instars have a high level of juvenile hormone, the moult to the pupal stage has a low level of juvenile ... Slama; Williams (1965). "Juvenile hormone activity for the bug Pyrrhocoris apterus". Proceedings of the National Academy of ... Singh, Amit; Konopova, Barbora; Smykal, Vlastimil; Jindra, Marek (2011). "Common and Distinct Roles of Juvenile Hormone ...
Dhadialla TS, Carlson GR, Le DP (1998). "New insecticides with ecdysteroidal and juvenile hormone activity". Annu. Rev. Entomol ... Vitamins & Hormones. 60: 1-73. doi:10.1016/S0083-6729(00)60016-X. ISBN 978-0-12-709860-9. PMID 11037621. Syed MH, Mark B, Doe ... Vitamins & Hormones. 73: 59-100. doi:10.1016/S0083-6729(05)73003-X. ISBN 0-12-709873-9. PMID 16399408. Graham LD (June 2002). " ... EcR and USP share the multi-domain architecture common to all nuclear hormone receptors, namely an N-terminal transcriptional ...
Instead, it prevents immature insects from reaching maturity by mimicking juvenile hormone. Fenoxycarb in the Pesticide ... "New insecticides with ecdysteroidal and juvenile hormone activity". Annual Review of Entomology. Annual Reviews. 43 (1): 545- ...
"Juvenile hormone and the ontogeny of cockroach aggression". Hormones and Behavior. 56 (3): 332-338. doi:10.1016/j.yhbeh.2009.06 ... Researchers theorize that this lack of change in social hierarchies even under the influence of aggression hormones is due to ... This will cause low-ranking animals treated with aggression hormones to behave aggressively towards animals from other groups ...
Juvenile hormone is synthesised in the corpora allata. In every insect tested, at least one of the three types of Allatostatin ... They have a twofold function: they both inhibit the generation of juvenile hormone and reduce their food intake. They are ... Stay B, Tobe SS (2007). "The role of allatostatins in juvenile hormone synthesis in insects and crustaceans". Annu. Rev. ... Other amine and neuropeptide neurotransmitters may also inhibit juvenile hormone biosynthesis. ...
These assist the juvenile hormone in determining the position of totipotent workers in the caste system. In ants, female larvae ... If the juvenile hormone titer is raised above a certain threshold, gynomorphs develop; otherwise, workers develop. Control of ... Juvenile hormones, for example, control pheromone production in the owl butterfly Mythimna unipuncta. These are produced in ... Juvenile hormones, however, interfere more indirectly with the circadian release of PBAN. Male butterflies of the Danainae ...
In all species, molting and juvenile hormones appear to regulate these changes. The figure to the right shows the stages of ... The juvenile phase is different in plants and animals, but in plants juvenility is an early phase of plant growth in which ... In animals, the juvenile stage is most commonly found in social mammals, such as wild dogs, monkeys, apes, lions, wolves, and ... "Juvenile Stage , Center for Academic Research and Training in Anthropogeny (CARTA)". carta.anthropogeny.org. Retrieved 25 April ...
Juvenile hormone released by mated females increased 2.5 fold. The profile of the juvenile hormone produced also changed - ... Transfer of Juvenile Hormone During Copulation by Male to Female and Stimulation of Biosynthesis of Endogenous Juvenile Hormone ... In males, juvenile hormone is synthesized in small quantities by accessory sex glands. At birth, males synthesize around 1.5 ... In Chloridea virescens, juvenile hormone (JH, which regulates many aspects of insect development) is necessary for the ...
The application of juvenile hormone to worker honey bees has been shown to alter the tasks that they undertake indicating the ... "Regulation of honey bee age polyethism by juvenile hormone". Behavioral Ecology and Sociobiology. 20 (5): 329-338. doi:10.1007/ ...
W. S. Bowers; H. M. Fales; M. J. Thompson; E. C. Uebel (1966-11-25). "Juvenile Hormone: Identification of an Active Compound ... Karel Slama & Carroll M. Williams (1965). "Juvenile hormone activity for the bug Pyrrhocoris apterus" (PDF). Proceedings of the ... it mimics juvenile hormone closely at the chemical level, defending against vulnerable pests. Nymph Firebugs in Spain showing ... This hormone happened to have a profound effect on P. apterus, but not on other insect species, showing the diversification of ...
Roseler, P. F. (1977). "Juvenile hormone control of oogenesis in bumblebee workers, B. terrestris". Journal of Insect ...
The juvenile hormone also plays a role in ovarian development. When the corpora allata is removed in females, the ovaries are ... The juvenile hormone, released by the corpora allota, is necessary for females to produce and release pheromones through their ... Cusson, M. & McNeil, J. N. (1989). "Involvement of Juvenile Hormone in the Regulation of Pheromone Release Activities in a Moth ... The production and release of the pheromones are influenced by temperature, photoperiod, and the juvenile hormone. Hearing is ...
When the juvenile hormone is present also, larvae moult to another larval stage. Juvenile hormone is not present during the ... Williams was the first to isolate juvenile hormone and ecdysone. With his students he studied cocoon-spinning behavior and the ... He showed that a hormone from the brain activated the prothoracic glands to release the moulting hormone ecdysone. ... The pupae enter diapause which is broken when the brain has been chilled for weeks, after which it releases the brain hormone. ...
Watt, G. R.; Davey, K. G. (1996). "Cellular and Molecular Actions of Juvenile Hormone. II. Roles of Juvenile Hormone in Adult ... JH is principally degraded by the enzymes juvenile-hormone esterase (JHE) or juvenile hormone epoxide hydrolase (JHEH). JHE and ... Juvenile Hormone Sullivan, J. P., Jassim, O., Fahrbach, S. E. and Robinson, G. E. (2000). Juvenile hormone paces behavioral ... "Juvenile Hormone Bisepoxide Biosynthesis in vitro by the Ring Gland of Drosophila melanogaster: A putative juvenile Hormone in ...
... the transition from juvenile development to the adult stage is controlled by juvenile hormone (JH) synthesized from the corpora ... Whereas a JH-free period during the last juvenile instar triggers metamorphosis and the end of the growth period, the ... Here, using the hemimetabolous insect Blattella germanica, we show that nuclear hormone receptors Seven-up-B (BgSvp-B) and ... reappearance of this hormone after the imaginal molt marks the onset of reproductive adulthood. Despite the importance of such ...
Yue-Shu Yu, Shan Xue, Jin-Cai Wu, Fang Wang, and Guo-Qin Yang "Changes in Levels of Juvenile Hormone and Molting Hormone in ... Yue-Shu Yu, Shan Xue, Jin-Cai Wu, Fang Wang, Guo-Qin Yang "Changes in Levels of Juvenile Hormone and Molting Hormone in Larvae ... Changes in Levels of Juvenile Hormone and Molting Hormone in Larvae and Adult Females of Chilo suppressalis (Lepidoptera: ... The current study investigated changes in juvenile hormone (JH) and molting hormone (MH) levels in fourth instars and adult ...
Generally, hormones are secreted by glands and perform a systemic action. Here we show that Juvenile Hormones (JHs), insect ... our results identify JHs as key hormonal regulators of gut homeostasis and open the possibility that analogous hormones may ... Hormones play essential roles during development and maintaining homeostasis in adult organisms, regulating a plethora of ... Local juvenile hormone activity regulates gut homeostasis and tumor growth in adult Drosophila. ...
Scientists are interested in juvenile hormone. One way to work on this question is to study the hormone in a bee that ... Somewhere along the evolutionary history of these bees, juvenile hormone stopped doing one job, and started doing a different ... Our experiments on juvenile hormone effects on bumble bee behavior will tell us if these pesticides are safe to use with bumble ... In these worker honey bees, a substance called juvenile hormone is not involved in egg laying. Instead, it determines when the ...
Parents of juvenile-hormone esterase activity (GO:0004453) subject. relation. object. juvenile-hormone esterase activity is_a ... JH esterase activity, JH-esterase activity, juvenile hormone analog esterase activity, juvenile hormone carboxyesterase ... A carboxylesterase that hydrolyzes the ester linkage of juvenile hormone. Source: PMID:11267890. , RHEA:16393. Comment. None. ... Link to all annotated objects annotated to juvenile-hormone esterase activity. Link to all direct and indirect annotations to ...
Dive into the research topics of Juvenile hormone and locust phase. Together they form a unique fingerprint. ...
An experience of sequental use of three biologics and recombinant growth hormone in a patient with juvenile idiopathic ... An experience of sequental use of three biologics and recombinant growth hormone in a patient with juvenile idiopathic ... An experience of sequental use of three biologics and recombinant growth hormone in a patient with juvenile idiopathic ... Recovery of linear growth is quite often reached as result of biologics therapy, but use of recombinant growth hormone (rGH) ...
... and juvenile hormones (Met) interact to mediate cross-talk between these two important hormones. ... and juvenile hormones (Met) interact to mediate cross-talk between these two important hormones.", ... and juvenile hormones (Met) interact to mediate cross-talk between these two important hormones. ... and juvenile hormones (Met) interact to mediate cross-talk between these two important hormones. ...
... ... Growth hormone (GH) was applied to Atlantic salmon Salmo salar parr (the pre-migratory freshwater life stage) to manipulate ... with the hormone having an effect only during the early part of the summer. Regardless of treatment, fish that moved most ...
THE CONCENTRATION OF JUVENILE HORMONE IN FEMALE ADULTS OF COCCINELLA SEPTEMPUNCTATA DURING OVARIAN DEVELOPMENT FU YI-LING, CHEN ... THE CONCENTRATION OF JUVENILE HORMONE IN FEMALE ADULTS OF COCCINELLA SEPTEMPUNCTATA DURING OVARIAN DEVELOPMENT[J]., 1984, 27(3 ... Molecular mechanisms of juvenile hormone in insect metamorphosis [J]. , 2017, 60(5): 594-603. ... Effects of application of juvenile hormone and precocene on physiological trade-offs between flight muscle and reproductive ...
Synthesis and anti-juvenile hormone activity of ethyl 4-(2-benzylalkyloxy) benzoates and their enantiomers. In: Journal of ... Synthesis and anti-juvenile hormone activity of ethyl 4-(2-benzylalkyloxy) benzoates and their enantiomers. Journal of ... Synthesis and anti-juvenile hormone activity of ethyl 4-(2-benzylalkyloxy) benzoates and their enantiomers. / Furuta, Kenjiro; ... Furuta, K, Ashibe, K, Shirahashi, H, Fujita, N, Yamashita, H, Yamada, N & Kuwano, E 2007, Synthesis and anti-juvenile hormone ...
2014). Metabolic analysis reveals changes in the mevalonate and juvenile hormone synthesis pathways linked to the mosquito ... 2014). Metabolic analysis reveals changes in the mevalonate and juvenile hormone synthesis pathways linked to the mosquito ... Metabolic analysis reveals changes in the mevalonate and juvenile hormone synthesis pathways linked to the mosquito ...
... juvenile hormone analogue Brand: FRONTLINE ® PLUS. Company: BOEHRINGER INGELHEIM (MERIAL). FORMULATION: «spot-on» solution for ...
Their chemical structures are similar to that of juvenile hormone (JH) and have been suspected to mimic JH signaling in ... Phurealipids, produced by the entomopathogenic bacteria, Photorhabdus, mimic juvenile hormone to suppress insect immunity and ... Phurealipids, produced by the entomopathogenic bacteria, Photorhabdus, mimic juvenile horm ...
Combined transcriptome sequencing and gene family analysis further revealed that four juvenile hormone esterase (JHE)-family ... and the juvenile hormone (JH) titers maintained in insects. Nerolidol, a natural sesquiterpenol belonging to the terpenoid ... the juvenile hormone esterase-like (JHEL) gene Sexi006721, a critical element responsive to nerolidol stress, was closely ... genes that are involved in juvenile hormone degradation were significantly altered in S. exigua larvae after nerolidol ...
Peptidic analogs of the juvenile hormone (JH) selectively interfere with development of linden bugs. Newly derived peptidic ... thus by far surpassing potency of the native linden bug hormone. ... Species-selective peptidic agonists of the juvenile hormone ...
Molecular Characterization of Primary Juvenile Hormone Responders Methoprene-Tolerant (Met) and Krüppel Homolog 1 (Kr-h1) in ... Molecular Characterization of Primary Juvenile Hormone Responders Methoprene-Tolerant (Met) and Krüppel Homolog 1 (Kr-h1) in ... Molecular Characterization of Primary Juvenile Hormone Responders Methoprene-Tolerant (Met) and Krüppel Homolog 1 (Kr-h1) in ...
... ecdysone and juvenile hormone); (iii) involve a depression or suppression of the oxidative metabolism with mitochondrial ...
juvenile hormone diol kinase. K16651 L-threonine kinase [EC:2.7.1.177]. K18201 hydroxylysine kinase [EC:2.7.1.81]. ...
Juvenile Hormone. *K. *Kin Discrimination. *Kin Recognition. *Kinship. *Kinship Theory. *L. *Large Carpenter Bees (Xylocopa) ...
Juvenile medaka anti-androgen screening assay (JMASA) (draft OECD GD).. *Short-term juvenile hormone activity screening assay ...
Juvenile Hormone and Ecdysone Mimics. Methoprene is the pioneer juvenile hormone analog and the most prominent. It is an ... They mimic the action of applied juvenile hormone, but are not subject to the same biochemical regulatory mechanisms. They ... between the potency of analogs for affecting head capsule slippage and ability to displace the binding of labeled hormone from ...
juvenile hormone metabolic process +. 0. pentalenolactone metabolic process +. 0. sesquiterpenoid biosynthetic process +. 0. ...
These results suggest that sp2 gene activity is affected by juvenile and molting hormones [24]. From the analysis of the ... T. S. Dhadialla, G. R. Carlson, and D. P. Le, "New insecticides with ecdysteroidal and juvenile hormone activity," Annual ... Owing to the influence of juvenile hormone and ecdysone, SP2 is synthesized by the fat body of feeding larvae and released into ...
Juvenile hormone (JH) and 20-hydroxy-ecdysone (20E) are highly versatile hormones, coordinating development, growth, ...
Journal Article] Molecular impact of juvenile hormone agonists on neonatal Daphnia magna.2014. *. Author(s). Toyota, K., Kato, ...
... a powerful synthetic analog of mosquito juvenile hormone (42). An effective prevention and control strategy against Aedes ...
Contact and stomach action, acts by mimicing the action of the juvenile hormone keeping the insect in an immature state. ...
  • Juvenile hormones are secreted by a pair of endocrine glands behind the brain called the corpora allata. (wikipedia.org)
  • The primary control of juvenile hormone is by 1) the stimulation of the corpora allata by allatotropins short peptides which bind to G-protein coupled receptors, which signal the glands to produce JH, and 2), the inhibition of JH production by allatostatins. (wikipedia.org)
  • Generally, the removal of the corpora allata from juveniles will result in a diminutive adult at the next moult. (wikipedia.org)
  • Implantation of corpora allata into last larval instars will boost JH levels and hence produce a supernumerary (extra) juvenile instar etc. (wikipedia.org)
  • In insects, the transition from juvenile development to the adult stage is controlled by juvenile hormone (JH) synthesized from the corpora allata (CA) glands. (nature.com)
  • Peptidic analogs of the juvenile hormone (JH) selectively interfere with development of linden bugs. (cas.cz)
  • Link to all annotated objects annotated to juvenile-hormone esterase activity. (planteome.org)
  • Link to all direct and indirect annotations to juvenile-hormone esterase activity. (planteome.org)
  • Secondary control of the JH titre found in the haemolymph of the developing insect is metabolic inactivation of JH by JH-specific esterase and juvenile hormone epoxide hydrolase. (wikipedia.org)
  • There is a complex interaction between JH, the hormone ecdysone and vitellogenin. (wikipedia.org)
  • Owing to the influence of juvenile hormone and ecdysone, SP2 is synthesized by the fat body of feeding larvae and released into the hemolymph [ 9 ]. (hindawi.com)
  • Juvenile hormone (JH) and 20-hydroxy-ecdysone (20E) are highly versatile hormones, coordinating development, growth, reproduction and aging in insects. (rero.ch)
  • Whereas a JH-free period during the last juvenile instar triggers metamorphosis and the end of the growth period, the reappearance of this hormone after the imaginal molt marks the onset of reproductive adulthood. (nature.com)
  • Postembryonic development in winged insects is divided into three stages: (i) a juvenile phase where growth takes place, (ii) the metamorphic transformation during the last juvenile instar, and (iii) the reproductive adulthood. (nature.com)
  • An 85 kDa protein identified in Drosophila melanogaster methoprene-tolerant (Met) mutant binds to JH III with high affinity, and the mutant flies are resistant to juvenile hormone analog (JHA), methoprene. (uky.edu)
  • Phurealipids, produced by the entomopathogenic bacteria, Photorhabdus, mimic juvenile hormone to suppress insect immunity and immature development. (bvsalud.org)
  • Their chemical structures are similar to that of juvenile hormone (JH) and have been suspected to mimic JH signaling in immunity and the development of insects . (bvsalud.org)
  • One type of IGR is a juvenile hormone (JH) mimic. (target-specialty.com)
  • Molecular mechanisms regulating the binding capacity of juvenile hormone response region (JHRR) to nuclear proteins in Drosophila melanogaster [J]. , 2016, 59(12): 1325-1331. (insect.org.cn)
  • Molecular cloning, sequence analysis and developmental expression of cDNA fragment of juvenile hormone esterase from the whitefly Bemisia tabaci MED (Hemiptera: Aleyrodidae) [J]. , 2013, 56(3): 234-242. (insect.org.cn)
  • Spruce budworm ( Choristoneura fumiferana ) juvenile hormone esterase: hormonal regulation, developmental expression and cDNA cloning. (gc.ca)
  • Newly derived peptidic juvenoids bind and activate the JH receptor of the linden bug at picomolar doses, thus by far surpassing potency of the native linden bug hormone. (cas.cz)
  • Growth hormone circulates bound to a specific binding protein (GHBP), which is the extracellular portion of the growth hormone receptor. (medscape.com)
  • Electroencephalogram demonstrating polyspike and wave discharges seen in juvenile myoclonic epilepsy. (medscape.com)
  • Various plant species contain terpene secondary metabolites, which disrupt insect growth and development by affecting the activity of juvenile hormone-degrading enzymes, and the juvenile hormone (JH) titers maintained in insects. (mdpi.com)
  • In insects, JH (formerly neotenin) refers to a group of hormones, which ensure growth of the larva, while preventing metamorphosis. (wikipedia.org)
  • Insect hormones regulate growth and development and fecundity of insects. (bioone.org)
  • Many pest insects also use the hormone to produce eggs. (hoa-pr.com)
  • These pesticides overload the hormone system in the pest insects and stop them from laying eggs. (hoa-pr.com)
  • The timing of juvenile hormone signalling supports homology between stages of hemimetabolous and holometabolous insects. (cas.cz)
  • Here, using the hemimetabolous insect Blattella germanica , we show that nuclear hormone receptors Seven-up-B (BgSvp-B) and Fushi tarazu-factor 1 (BgFTZ-F1) have essential roles in the tissue- and stage-specific activation of adult CA JH-biosynthetic activity. (nature.com)
  • Moreover, a study by Liu et al found that JNAs express higher levels of hormone receptors and vascular endothelial growth factor (VEGF) than does normal nasal mucosa, a possible indication that interaction between the receptors and VEGF is associated with JNA initiation and growth. (medscape.com)
  • Anopheles funestus, Anopheles stephensi, Anopheles minimus and Anopheles albimanus) to seven public health insecticides in five classes, including pyrethroids (metofluthrin, prallethrin and transfluthrin), neonicotinoids (clothianidin), pyrroles (chlorfenapyr), juvenile hormone mimics (pyriproxyfen) and butenolides (flupyradifurone), in glass bottle assays. (cdc.gov)
  • Juvenile hormones (JHs) are a group of acyclic sesquiterpenoids that regulate many aspects of insect physiology. (wikipedia.org)
  • Ecdysteroids and juvenile hormones (JH) regulate a variety of developmental, physiological, behavioral, and metabolic processes. (uky.edu)
  • In addition to these transcription factors, several peptide hormones (allatotropins, allatostatins and short neuropeptide F) and neurotransmitters (the biogenic amines octopamine, dopamine and glutamate) are also involved in the regulation of CA activity 16 . (nature.com)
  • Rivera-Pérez C., Clifton M.E., Noriega F., Jindra M. (2020) Juvenile hormone regulation and function. (cas.cz)
  • Ghrelin may play a role in regulation of growth hormone at the hypothalamic level, permitting an adequate energy supply for maintenance, growth, and repair. (medscape.com)
  • Thus, the presence of JH during pre-ultimate juvenile stages prevents the premature differentiation of adult features, while its disappearance upon entering into the last immature stage allows metamorphosis to occur 4 . (nature.com)
  • Molecular mechanisms of juvenile hormone in insect metamorphosis [J]. , 2017, 60(5): 594-603. (insect.org.cn)
  • A number of ethyl 4-(2-benzylalkyloxy)benzoates were prepared and their activity to induce precocious metamorphosis was evaluated in larvae of the silkworm, Bombyx mori, which was clearly recognized as a juvenile hormone (JH)-deficiency symptom. (elsevierpure.com)
  • Being a sesquiterpenoid, JH chemical structure differs significantly from the structure of other animal hormones. (wikipedia.org)
  • Effects of application of juvenile hormone and precocene on physiological trade-offs between flight muscle and reproductive development in the wing dimorphic cricket Velarifictorus ornatus (Orthoptera: Gryllidae) (In English) [J]. , 2013, 56(6): 622-629. (insect.org.cn)
  • Females with juvenile nasopharyngeal angiofibroma (JNA) should undergo genetic testing. (medscape.com)
  • Short stature and hip lesions are typical complications of juvenile idiopathic arthritis (JIA) especially in systemic and polyarticular variants with early onset. (biomedcentral.com)
  • When growth hormone pulses are secreted into the systemic circulation, insulinlike growth factor (IGF)-1 is released, either locally or at the site of the growing bone. (medscape.com)
  • The 2 general clinical categories of paracoccidioidomycosis are (1) an acute/subacute form (juvenile paracoccidioidomycosis) and (2) a chronic form (adult paracoccidioidomycosis). (medscape.com)
  • Changes in the transcriptional levels of pyridoxal kinase and pyridoxine-5′-phosphate oxidase post exogenous hormone treatment in the silkworm, Bombyx mori [J]. , 2015, 58(12): 1285-1290. (insect.org.cn)
  • In contrast, molting hormone (MH) level in larvae fed on control plants was significantly higher than that on treated plants. (bioone.org)
  • In these worker honey bees, a substance called juvenile hormone is not involved in egg laying. (hoa-pr.com)
  • There are also insecticides based on nuclear polyhedrosis virus (NPV) and insect hormones. (encyclopedia.com)
  • Most insect species contain only juvenile growth hormone (JH) III. (wikipedia.org)
  • Certain species of crustaceans have been shown to produce and secrete methyl farnesoate, which is juvenile hormone III lacking the epoxide group. (wikipedia.org)
  • Growth hormone (GH) was applied to Atlantic salmon Salmo salar parr (the pre-migratory freshwater life stage) to manipulate growth potential experimentally and to elucidate the effects on dominance status, actual growth, exploratory activity and home range. (edu.au)
  • These data suggest that the proteins that are involved in signal transduction of ecdysteroids (EcR and USP) and juvenile hormones (Met) interact to mediate cross-talk between these two important hormones. (uky.edu)
  • Type 1 diabetes was once called insulin-dependent or juvenile diabetes, but it can develop at any age. (cdc.gov)
  • Microglial Phagocytosis of Newborn Cells Is Induced by Endocannabinoids and Sculpts Sex Differences in Juvenile Rat Social Play. (nih.gov)
  • However, says Siegel, "we do not know what effects juvenile hormone has on bumble bee pollination. (hoa-pr.com)
  • Our experiments on juvenile hormone effects on bumble bee behavior will tell us if these pesticides are safe to use with bumble bee pollinators, or if they will hurt the foraging bumble bees. (hoa-pr.com)
  • Effects of juvenile hormone on mammalian steroidogenesis. (umassmed.edu)
  • The GH stimulated increase in fork length (L F) and mass and decrease in condition factor due to the relatively greater increase in L F. There was, however, an interaction between GH-stimulated increase in growth and season, with the hormone having an effect only during the early part of the summer. (edu.au)
  • Because the hormone has to be present at very specific concentrations to work correctly, farmers can spray pesticides on plants that include chemicals that work in the same way as the hormone. (hoa-pr.com)
  • Under varied temperatures, β-Tubulin and V-ATPase-A were most stable, whereas ubiquitin (UbiQ) and V-ATPase-A displayed the highest expression stability after Juvenile Hormone III treatment. (lu.se)