Joints. Medical search

Also known as articulations, these are points of connection between the ends of certain separate bones, or where the borders of other bones are juxtaposed.

A synovial hinge connection formed between the bones of the FEMUR; TIBIA; and PATELLA.

The articulation between the head of one phalanx and the base of the one distal to it, in each finger.

The joint that is formed by the inferior articular and malleolar articular surfaces of the TIBIA; the malleolar articular surface of the FIBULA; and the medial malleolar, lateral malleolar, and superior surfaces of the TALUS.

The joint that is formed by the articulation of the head of FEMUR and the ACETABULUM of the PELVIS.

The articulations between the various TARSAL BONES. This does not include the ANKLE JOINT which consists of the articulations between the TIBIA; FIBULA; and TALUS.

The joint that is formed by the distal end of the RADIUS, the articular disc of the distal radioulnar joint, and the proximal row of CARPAL BONES; (SCAPHOID BONE; LUNATE BONE; triquetral bone).

The sac enclosing a joint. It is composed of an outer fibrous articular capsule and an inner SYNOVIAL MEMBRANE.

The immovable joint formed by the lateral surfaces of the SACRUM and ILIUM.

Lack of stability of a joint or joint prosthesis. Factors involved are intra-articular disease and integrity of extra-articular structures such as joint capsule, ligaments, and muscles.

A variety of conditions affecting the anatomic and functional characteristics of the temporomandibular joint. Factors contributing to the complexity of temporomandibular diseases are its relation to dentition and mastication and the symptomatic effects in other areas which account for referred pain to the joint and the difficulties in applying traditional diagnostic procedures to temporomandibular joint pathology where tissue is rarely obtained and x-rays are often inadequate or nonspecific. Common diseases are developmental abnormalities, trauma, subluxation, luxation, arthritis, and neoplasia. (From Thoma's Oral Pathology, 6th ed, pp577-600)

The articulation between a metatarsal bone (METATARSAL BONES) and a phalanx.

The articulations extending from the ANKLE distally to the TOES. These include the ANKLE JOINT; TARSAL JOINTS; METATARSOPHALANGEAL JOINT; and TOE JOINT.

The articulation between the head of the HUMERUS and the glenoid cavity of the SCAPULA.

Prostheses used to partially or totally replace a human or animal joint. (from UMDNS, 1999)

A plate of fibrous tissue that divides the temporomandibular joint into an upper and lower cavity. The disc is attached to the articular capsule and moves forward with the condyle in free opening and protrusion. (Boucher's Clinical Dental Terminology, 4th ed, p92)

The gliding joint formed by the outer extremity of the CLAVICLE and the inner margin of the acromion process of the SCAPULA.

A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.

A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.

A double gliding joint formed by the CLAVICLE, superior and lateral parts of the manubrium sterni at the clavicular notch, and the cartilage of the first rib.

A protective layer of firm, flexible cartilage over the articulating ends of bones. It provides a smooth surface for joint movement, protecting the ends of long bones from wear at points of contact.

The clear, viscous fluid secreted by the SYNOVIAL MEMBRANE. It contains mucin, albumin, fat, and mineral salts and serves to lubricate joints.

Methods of delivering drugs into a joint space.

The articulations between the CARPAL BONES and the METACARPAL BONES.

Inflammation of a synovial membrane. It is usually painful, particularly on motion, and is characterized by a fluctuating swelling due to effusion within a synovial sac. (Dorland, 27th ed)

The properties, processes, and behavior of biological systems under the action of mechanical forces.

The inner membrane of a joint capsule surrounding a freely movable joint. It is loosely attached to the external fibrous capsule and secretes SYNOVIAL FLUID.

The distance and direction to which a bone joint can be extended. Range of motion is a function of the condition of the joints, muscles, and connective tissues involved. Joint flexibility can be improved through appropriate MUSCLE STRETCHING EXERCISES.

ARTHRITIS that is induced in experimental animals. Immunological methods and infectious agents can be used to develop experimental arthritis models. These methods include injections of stimulators of the immune response, such as an adjuvant (ADJUVANTS, IMMUNOLOGIC) or COLLAGEN.

Roentgenography of a joint, usually after injection of either positive or negative contrast medium.

Arthritis caused by BACTERIA; RICKETTSIA; MYCOPLASMA; VIRUSES; FUNGI; or PARASITES.

Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)

Pain in the joint.

The articulations between the various CARPAL BONES. This does not include the WRIST JOINT which consists of the articulations between the RADIUS; ULNA; and proximal CARPAL BONES.

The articulation between the articular surface of the PATELLA and the patellar surface of the FEMUR.

The physical state of supporting an applied load. This often refers to the weight-bearing bones or joints that support the body's weight, especially those in the spine, hip, knee, and foot.

Partial or total replacement of a joint.

The act, process, or result of passing from one place or position to another. It differs from LOCOMOTION in that locomotion is restricted to the passing of the whole body from one place to another, while movement encompasses both locomotion but also a change of the position of the whole body or any of its parts. Movement may be used with reference to humans, vertebrate and invertebrate animals, and microorganisms. Differentiate also from MOTOR ACTIVITY, movement associated with behavior.

Fibrous cords of CONNECTIVE TISSUE that attach bones to each other and hold together the many types of joints in the body. Articular ligaments are strong, elastic, and allow movement in only specific directions, depending on the individual joint.

In horses, cattle, and other quadrupeds, the joint between the femur and the tibia, corresponding to the human knee.

A symptom complex consisting of pain, muscle tenderness, clicking in the joint, and limitation or alteration of mandibular movement. The symptoms are subjective and manifested primarily in the masticatory muscles rather than the temporomandibular joint itself. Etiologic factors are uncertain but include occlusal dysharmony and psychophysiologic factors.

Prolonged shortening of the muscle or other soft tissue around a joint, preventing movement of the joint.

Fixation and immobility of a joint.

Drugs that are used to treat RHEUMATOID ARTHRITIS.

A private, voluntary, not-for-profit organization which establishes standards for the operation of health facilities and services, conducts surveys, and awards accreditation.

Manner or style of walking.

The second longest bone of the skeleton. It is located on the medial side of the lower leg, articulating with the FIBULA laterally, the TALUS distally, and the FEMUR proximally.

Infections resulting from the implantation of prosthetic devices. The infections may be acquired from intraoperative contamination (early) or hematogenously acquired from other sites (late).

The rotational force about an axis that is equal to the product of a force times the distance from the axis where the force is applied.

Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.

Replacement of the knee joint.

Bleeding into the joints. It may arise from trauma or spontaneously in patients with hemophilia.

Endoscopic examination, therapy and surgery of the joint.

Bony outgrowth usually found around joints and often seen in conditions such as ARTHRITIS.

Either of two extremities of four-footed non-primate land animals. It usually consists of a FEMUR; TIBIA; and FIBULA; tarsals; METATARSALS; and TOES. (From Storer et al., General Zoology, 6th ed, p73)

The longest and largest bone of the skeleton, it is situated between the hip and the knee.

A type of inflammatory arthritis associated with PSORIASIS, often involving the axial joints and the peripheral terminal interphalangeal joints. It is characterized by the presence of HLA-B27-associated SPONDYLARTHROPATHY, and the absence of rheumatoid factor.

A non-vascular form of connective tissue composed of CHONDROCYTES embedded in a matrix that includes CHONDROITIN SULFATE and various types of FIBRILLAR COLLAGEN. There are three major types: HYALINE CARTILAGE; FIBROCARTILAGE; and ELASTIC CARTILAGE.

Surgical reconstruction of a joint to relieve pain or restore motion.

Pathological processes involving the chondral tissue (CARTILAGE).

Polymorphic cells that form cartilage.

An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

The application of LUBRICANTS to diminish FRICTION between two surfaces.

The distal part of the arm beyond the wrist in humans and primates, that includes the palm, fingers, and thumb.

A fibrillar collagen found predominantly in CARTILAGE and vitreous humor. It consists of three identical alpha1(II) chains.

Deformities acquired after birth as the result of injury or disease. The joint deformity is often associated with rheumatoid arthritis and leprosy.

The interarticular fibrocartilages of the superior surface of the tibia.

An articulation where the costal cartilage of each rib fit with slight concavities along the lateral borders of the STERNUM.

The flat, triangular bone situated at the anterior part of the KNEE.

A front limb of a quadruped. (The Random House College Dictionary, 1980)

Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.

Injuries to the knee or the knee joint.

A strong ligament of the knee that originates from the posteromedial portion of the lateral condyle of the femur, passes anteriorly and inferiorly between the condyles, and attaches to the depression in front of the intercondylar eminence of the tibia.

Sensory functions that transduce stimuli received by proprioceptive receptors in joints, tendons, muscles, and the INNER EAR into neural impulses to be transmitted to the CENTRAL NERVOUS SYSTEM. Proprioception provides sense of stationary positions and movements of one's body parts, and is important in maintaining KINESTHESIA and POSTURAL BALANCE.

The inner and longer bone of the FOREARM.

The region corresponding to the human WRIST in non-human ANIMALS.

Fibrous bands or cords of CONNECTIVE TISSUE at the ends of SKELETAL MUSCLE FIBERS that serve to attach the MUSCLES to bones and other structures.

Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.

Measurements of joint flexibility (RANGE OF MOTION, ARTICULAR), usually by employing an angle-measuring device (arthrometer). Arthrometry is used to measure ligamentous laxity and stability. It is often used to evaluate the outcome of ANTERIOR CRUCIATE LIGAMENT replacement surgery.

A growth differentiation factor that plays a role in early CHONDROGENESIS and joint formation.

Replacement for a knee joint.

Presence of calcium salts, especially calcium pyrophosphate, in the cartilaginous structures of one or more joints. When accompanied by attacks of goutlike symptoms, it is called pseudogout. (Dorland, 27th ed)

A dead body, usually a human body.

The eight bones of the wrist: SCAPHOID BONE; LUNATE BONE; TRIQUETRUM BONE; PISIFORM BONE; TRAPEZIUM BONE; TRAPEZOID BONE; CAPITATE BONE; and HAMATE BONE.

Sense of movement of a part of the body, such as movement of fingers, elbows, knees, limbs, or weights.

A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area.

Recording of the changes in electric potential of muscle by means of surface or needle electrodes.

The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.

The point of articulation between the OCCIPITAL BONE and the CERVICAL ATLAS.

The region in the hindlimb of a quadruped, corresponding to the human ANKLE.

The distal extremity of the leg in vertebrates, consisting of the tarsus (ANKLE); METATARSUS; phalanges; and the soft tissues surrounding these bones.

Elements of limited time intervals, contributing to particular results or situations.

The position or attitude of the body.

The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.

General or unspecified injuries involving the fingers.

Motion of an object in which either one or more points on a line are fixed. It is also the motion of a particle about a fixed point. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

A number of ligaments on either side of, and serving as a radius of movement of, a joint having a hingelike movement. They occur at the elbow, knee, wrist, metacarpo- and metatarsophalangeal, proximal interphalangeal, and distal interphalangeal joints of the hands and feet. (Stedman, 25th ed)

The farthest or outermost projections of the body, such as the HAND and FOOT.

The restriction of the MOVEMENT of whole or part of the body by physical means (RESTRAINT, PHYSICAL) or chemically by ANALGESIA, or the use of TRANQUILIZING AGENTS or NEUROMUSCULAR NONDEPOLARIZING AGENTS. It includes experimental protocols used to evaluate the physiologic effects of immobility.

Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.

A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.

VERTEBRAE in the region of the lower BACK below the THORACIC VERTEBRAE and above the SACRAL VERTEBRAE.

Diseases of BONES.

Arthritis of children, with onset before 16 years of age. The terms juvenile rheumatoid arthritis (JRA) and juvenile idiopathic arthritis (JIA) refer to classification systems for chronic arthritis in children. Only one subtype of juvenile arthritis (polyarticular-onset, rheumatoid factor-positive) clinically resembles adult rheumatoid arthritis and is considered its childhood equivalent.

Tuberculosis of the bones or joints.

An activity in which the body advances at a slow to moderate pace by moving the feet in a coordinated fashion. This includes recreational walking, walking for fitness, and competitive race-walking.

Shiny, flexible bands of fibrous tissue connecting together articular extremities of bones. They are pliant, tough, and inextensile.

Bone in humans and primates extending from the SHOULDER JOINT to the ELBOW JOINT.

Surgical procedure to relax the JOINT CAPSULE tissues in a joint that has a reduced range of motion due to CONTRACTURE or TISSUE ADHESIONS or joint deformities.

The surgical cutting of a bone. (Dorland, 28th ed)

Three-dimensional representation to show anatomic structures. Models may be used in place of intact animals or organisms for teaching, practice, and study.

Bone diseases caused by pathogenic microorganisms.

Large HYALURONAN-containing proteoglycans found in articular cartilage (CARTILAGE, ARTICULAR). They form into aggregates that provide tissues with the capacity to resist high compressive and tensile forces.

Any of a group of bone disorders involving one or more ossification centers (EPIPHYSES). It is characterized by degeneration or NECROSIS followed by revascularization and reossification. Osteochondrosis often occurs in children causing varying degrees of discomfort or pain. There are many eponymic types for specific affected areas, such as tarsal navicular (Kohler disease) and tibial tuberosity (Osgood-Schlatter disease).

The hemispheric articular surface at the upper extremity of the thigh bone. (Stedman, 26th ed)

A natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. It is found in the UMBILICAL CORD, in VITREOUS BODY and in SYNOVIAL FLUID. A high urinary level is found in PROGERIA.

A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.

Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.

The second largest of the TARSAL BONES. It articulates with the TIBIA and FIBULA to form the ANKLE JOINT.

The projecting part on each side of the body, formed by the side of the pelvis and the top portion of the femur.

Surface resistance to the relative motion of one body against the rubbing, sliding, rolling, or flowing of another with which it is in contact.

Interruption of NEURAL CONDUCTION in peripheral nerves or nerve trunks by the injection of a local anesthetic agent (e.g., LIDOCAINE; PHENOL; BOTULINUM TOXINS) to manage or treat pain.

Measurement of rate of settling of erythrocytes in anticoagulated blood.

Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.

Movement or the ability to move from one place or another. It can refer to humans, vertebrate or invertebrate animals, and microorganisms.

Replacement for a hip joint.

Pain in the facial region including orofacial pain and craniofacial pain. Associated conditions include local inflammatory and neoplastic disorders and neuralgic syndromes involving the trigeminal, facial, and glossopharyngeal nerves. Conditions which feature recurrent or persistent facial pain as the primary manifestation of disease are referred to as FACIAL PAIN SYNDROMES.

Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.

Procedures used to treat and correct deformities, diseases, and injuries to the MUSCULOSKELETAL SYSTEM, its articulations, and associated structures.

The spinal or vertebral column.

Non-neoplastic tumor-like lesions at joints, developed from the SYNOVIAL MEMBRANE of a joint through the JOINT CAPSULE into the periarticular tissues. They are filled with SYNOVIAL FLUID with a smooth and translucent appearance. A synovial cyst can develop from any joint, but most commonly at the back of the knee, where it is known as POPLITEAL CYST.

Antibodies found in adult RHEUMATOID ARTHRITIS patients that are directed against GAMMA-CHAIN IMMUNOGLOBULINS.

Inflammation of the synovial lining of a tendon sheath. Causes include trauma, tendon stress, bacterial disease (gonorrhea, tuberculosis), rheumatic disease, and gout. Common sites are the hand, wrist, shoulder capsule, hip capsule, hamstring muscles, and Achilles tendon. The tendon sheaths become inflamed and painful, and accumulate fluid. Joint mobility is usually reduced.

A subspecialty of internal medicine concerned with the study of inflammatory or degenerative processes and metabolic derangement of connective tissue structures which pertain to a variety of musculoskeletal disorders, such as arthritis.

A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH).

A chronic inflammatory condition affecting the axial joints, such as the SACROILIAC JOINT and other intervertebral or costovertebral joints. It occurs predominantly in young males and is characterized by pain and stiffness of joints (ANKYLOSIS) with inflammation at tendon insertions.

A surgical specialty which utilizes medical, surgical, and physical methods to treat and correct deformities, diseases, and injuries to the skeletal system, its articulations, and associated structures.

A hereditary disease of the hip joints in dogs. Signs of the disease may be evident any time after 4 weeks of age.

Chronic progressive degeneration of the stress-bearing portion of a joint, with bizarre hypertrophic changes at the periphery. It is probably a complication of a variety of neurologic disorders, particularly TABES DORSALIS, involving loss of sensation, which leads to relaxation of supporting structures and chronic instability of the joint. (Dorland, 27th ed)

The outer shorter of the two bones of the FOREARM, lying parallel to the ULNA and partially revolving around it.

Disorders of connective tissue, especially the joints and related structures, characterized by inflammation, degeneration, or metabolic derangement.

The ligament that travels from the medial epicondyle of the FEMUR to the medial margin and medial surface of the TIBIA. The medial meniscus is attached to its deep surface.

The region of the HAND between the WRIST and the FINGERS.

Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.

Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.

The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material).

A partial or complete return to the normal or proper physiologic activity of an organ or part following disease or trauma.

Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.

Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

The superior part of the upper extremity between the SHOULDER and the ELBOW.

Computer-based representation of physical systems and phenomena such as chemical processes.

PROTEOGLYCANS-associated proteins that are major components of EXTRACELLULAR MATRIX of various tissues including CARTILAGE; and INTERVERTEBRAL DISC structures. They bind COLLAGEN fibers and contain protein domains that enable oligomer formation and interaction with other extracellular matrix proteins such as CARTILAGE OLIGOMERIC MATRIX PROTEIN.

Acute or chronic pain located in the posterior regions of the THORAX; LUMBOSACRAL REGION; or the adjacent regions.

Part of the body in humans and primates where the arms connect to the trunk. The shoulder has five joints; ACROMIOCLAVICULAR joint, CORACOCLAVICULAR joint, GLENOHUMERAL joint, scapulathoracic joint, and STERNOCLAVICULAR joint.

The five cylindrical bones of the METACARPUS, articulating with the CARPAL BONES proximally and the PHALANGES OF FINGERS distally.

Hereditary metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of uric acid calculi.

The part of the foot between the tarsa and the TOES.

Major component of chondrocyte EXTRACELLULAR MATRIX of various tissues including bone, tendon, ligament, SYNOVIUM and blood vessels. It binds MATRILIN PROTEINS and is associated with development of cartilage and bone.

Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.

The seven bones which form the tarsus - namely, CALCANEUS; TALUS; cuboid, navicular, and the internal, middle, and external cuneiforms.

The forepart of the foot including the metatarsals and the TOES.

The joining of pieces of metal through the use of an alloy which has a lower melting point, usually at least 100 degrees Celsius below the fusion temperature of the parts being soldered. In dentistry, soldering is used for joining components of a dental appliance, as in assembling a bridge, joining metals to orthodontic bands, or adding to the bulk of certain structures, such as the establishment of proper contact areas on inlays and crowns with adjacent teeth. (Illustrated Dictionary of Dentistry, 1982)

Applies to movements of the forearm in turning the palm backward or downward. When referring to the foot, a combination of eversion and abduction movements in the tarsal and metatarsal joints (turning the foot up and in toward the midline of the body).

Substances that reduce or suppress INFLAMMATION.

An extracellular endopeptidase of vertebrate tissues similar to MATRIX METALLOPROTEINASE 1. It digests PROTEOGLYCAN; FIBRONECTIN; COLLAGEN types III, IV, V, and IX, and activates procollagenase. (Enzyme Nomenclature, 1992)

An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.

A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.

The washing of a body cavity or surface by flowing water or solution for therapy or diagnosis.

The region of the lower limb between the FOOT and the LEG.

Lateral displacement of the great toe (HALLUX), producing deformity of the first METATARSOPHALANGEAL JOINT with callous, bursa, or bunion formation over the bony prominence.

Applies to movements of the forearm in turning the palm forward or upward. When referring to the foot, a combination of adduction and inversion movements of the foot.

Acute or chronic pain in the lumbar or sacral regions, which may be associated with musculo-ligamentous SPRAINS AND STRAINS; INTERVERTEBRAL DISK DISPLACEMENT; and other conditions.

A degenerative joint disease involving the SPINE. It is characterized by progressive deterioration of the spinal articular cartilage (CARTILAGE, ARTICULAR), usually with hardening of the subchondral bone and outgrowth of bone spurs (OSTEOPHYTE).

Tomography using x-ray transmission and a computer algorithm to reconstruct the image.

The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.

Inflammation of the bone.

Region of the body immediately surrounding and including the ELBOW JOINT.

Macromolecular organic compounds that contain carbon, hydrogen, oxygen, nitrogen, and usually, sulfur. These macromolecules (proteins) form an intricate meshwork in which cells are embedded to construct tissues. Variations in the relative types of macromolecules and their organization determine the type of extracellular matrix, each adapted to the functional requirements of the tissue. The two main classes of macromolecules that form the extracellular matrix are: glycosaminoglycans, usually linked to proteins (proteoglycans), and fibrous proteins (e.g., COLLAGEN; ELASTIN; FIBRONECTINS; and LAMININ).

The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.

The part of the pelvis that comprises the pelvic socket where the head of FEMUR joins to form HIP JOINT (acetabulofemoral joint).

Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.

Inflammation of the joints of the SPINE, the intervertebral articulations.

Forcible or traumatic tear or break of an organ or other soft part of the body.

A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.

Production of an image when x-rays strike a fluorescent screen.

Also called the shoulder blade, it is a flat triangular bone, a pair of which form the back part of the shoulder girdle.

Exudates are fluids, CELLS, or other cellular substances that are slowly discharged from BLOOD VESSELS usually from inflamed tissues. Transudates are fluids that pass through a membrane or squeeze through tissue or into the EXTRACELLULAR SPACE of TISSUES. Transudates are thin and watery and contain few cells or PROTEINS.

The first seven VERTEBRAE of the SPINAL COLUMN, which correspond to the VERTEBRAE of the NECK.

Large, hoofed mammals of the family EQUIDAE. Horses are active day and night with most of the day spent seeking and consuming food. Feeding peaks occur in the early morning and late afternoon, and there are several daily periods of rest.

An order of flightless birds comprising the ostriches, which naturally inhabit open, low rainfall areas of Africa.

Congenital dislocation of the hip generally includes subluxation of the femoral head, acetabular dysplasia, and complete dislocation of the femoral head from the true acetabulum. This condition occurs in approximately 1 in 1000 live births and is more common in females than in males.

Bones that make up the SKELETON of the FINGERS, consisting of two for the THUMB, and three for each of the other fingers.

Injuries to the wrist or the wrist joint.

External devices which hold wires or pins that are placed through one or both cortices of bone in order to hold the position of a fracture in proper alignment. These devices allow easy access to wounds, adjustment during the course of healing, and more functional use of the limbs involved.

Displacement of the HUMERUS from the SCAPULA.

A collective term for muscle and ligament injuries without dislocation or fracture. A sprain is a joint injury in which some of the fibers of a supporting ligament are ruptured but the continuity of the ligament remains intact. A strain is an overstretching or overexertion of some part of the musculature.

Examination of any part of the body for diagnostic purposes by means of X-RAYS or GAMMA RAYS, recording the image on a sensitized surface (such as photographic film).

Pyorrhoea as cause of pyrexia. (1/2057)

Three patients with fever and malaise, one of whom also had joint pains, were extensively investigated before their condition was attributed to dental sepsis. Each patient recovered fully after appropriate dental treatment. Dental sepsis should be added to the list of possible causes of pyrexia of undetermined origin, and a routine dental examination should be carried out in each case. (+info)

Sensory afferent properties of immobilised or inflamed rat knees during continuous passive movement. (2/2057)

We studied the sensory afferent properties of normal, immobilised and inflamed rat knees by recording the activity of the medial articular nerve (MAN). When the knee was inflamed by kaolin-carrageenan or immobilised for six weeks, MAN activity significantly increased during rest and continuous passive motion (CPM). The maximal discharge rate tended to increase depending on the angular velocity of the CPM. When the knees were then rested for one hour before again starting CPM, activity was further increased at the initial CPM cycle, the 'post-rest effect'. Analysis of the conduction velocity showed that 94% and 66% of spike units on the recorded discharge of the immobilised and inflamed knees, respectively, belonged to fine nerve fibres. Our findings show that the sensory receptors in the knee are sensitised in a similar manner by immobilisation and by inflammation, suggesting a relationship to pain. The post-rest effect may be related to a characteristic symptom of osteoarthritis called 'starting pain'. (+info)

Histology and tissue chemistry of tidemark separation in hamsters. (3/2057)

Adult articular cartilage is divided by the tidemark into a deep calcified layer and a more superficial uncalcified layer. Histologic examination of articular cartilage from the knee joint of golden Syrian hamsters 123 days of age or older revealed defects at the tidemark in the tibia. Defects ranged from small separations of the calcified and uncalcified layers along the tidemark to progressively larger defects apparently formed by dissolution. These larger defects appeared as cavities in the noncalcified cartilage, had smooth rather than rough edges, frequently contained coalesced debris, and often resulted in a bulge in the articular surface. Occasionally, these large defects broke through the articular surface. Defects were not observed in tibial cartilage of younger (<90 days old) hamsters or in femoral cartilage from hamsters of any age. Exercise neither protected against nor increased the severity of the defects. Collagen cross-linking by pyridinoline was examined as a function of age and increased from 1,090 to 3,062 micromoles of pyridinoline/mole of hydroxyproline over the period of 1-9 months of age but was not correlated with defect formation. With increasing age, these focal tidemark defects could lead to osteoarthrosis-like cartilage lesions. (+info)

Transformations in embryonic motility in chick: kinematic correlates of type I and II motility at E9 and E12. (4/2057)

Soon after hatching, chicks exhibit an array of adaptive, coordinated behaviors. Chick embryos also acquire nearly 18 days of movement experience, referred to as embryonic motility, before hatching. The chick expresses three forms of motility, types I, II, and III, and each emerges at a different stage of embryonic development. Although much is known about the mechanisms associated with motility at early embryonic stages and at the onset of hatching, the transformations in behavior and underlying mechanisms are not fully understood. Thus the purpose of this study was to determine how motility is modified during the first expected transformation, from type I to type II. It was hypothesized that kinematic features for motility at embryonic day 12 (E12) would differ significantly from features at E9 because type II motility emerges during E11. Embryos were video taped for extended intervals in ovo at E9 or E12 and entire sequences of motility were computer digitized for kinematic analyses. Results reported here indicate that several of the kinematic features characteristic of motility at E9 are also reliable features at E12. On the basis of these findings, a kinematic definition of type I motility is posed for use in subsequent behavioral studies. Several parameters distinguished motility at E12 from E9. The most notable difference between ages was the less regular timing of repetitive limb movements at E12, a finding consistent with recent reports suggesting early motility is an emergent product of a transient neural network rather than a specialized pattern generator. As predicted from established definitions for type II motility, startle-like movements were common at E12; however, they also were present in many kinematic plots at E9, suggesting the discreet age-dependent boundaries in the established definition for type II motility may require modification. Some age-related differences, such as increased intralimb coordination and excursion velocity, may be prerequisites for adaptive behavior after hatching. (+info)

Role of proprioceptive signals from an insect femur-tibia joint in patterning motoneuronal activity of an adjacent leg joint. (5/2057)

Interjoint reflex function of the insect leg contributes to postural control at rest or to movement control during locomotor movements. In the stick insect (Carausius morosus), we investigated the role that sensory signals from the femoral chordotonal organ (fCO), the transducer of the femur-tibia (FT) joint, play in patterning motoneuronal activity in the adjacent coxa-trochanteral (CT) joint when the joint control networks are in the movement control mode of the active behavioral state. In the active behavioral state, sensory signals from the fCO induced transitions of activity between antagonistic motoneuron pools, i.e., the levator trochanteris and the depressor trochanteris motoneurons. As such, elongation of the fCO, signaling flexion of the FT joint, terminated depressor motoneuron activity and initiated activity in levator motoneurons. Relaxation of the fCO, signaling extension of the FT joint, induced the opposite transition by initiating depressor motoneuron activity and terminating levator motoneuron activity. This interjoint influence of sensory signals from the fCO was independent of the generation of the intrajoint reflex reversal in the FT joint, i.e., the "active reaction," which is released by elongation signals from the fCO. The generation of these transitions in activity of trochanteral motoneurons barely depended on position or velocity signals from the fCO. This contrasts with the situation in the resting behavioral state when interjoint reflex action markedly depends on actual fCO stimulus parameters, i.e., position and velocity signals. In the active behavioral state, movement signals from the fCO obviously trigger or release centrally generated transitions in motoneuron activity, e.g., by affecting central rhythm generating networks driving trochanteral motoneuron pools. This conclusion was tested by stimulating the fCO in "fictive rhythmic" preparations, activated by the muscarinic agonist pilocarpine in the otherwise isolated and deafferented mesothoracic ganglion. In this situation, sensory signals from the fCO did in fact reset and entrain rhythmic activity in trochanteral motoneurons. The results indicate for the first time that when the stick insect locomotor system is active, sensory signals from the proprioceptor of one leg joint, i.e., the fCO, pattern motor activity in an adjacent leg joint, i.e., the CT joint, by affecting the central rhythm generating network driving the motoneurons of the adjacent joint. (+info)

Prevention of collagen-induced arthritis in mice by a polyphenolic fraction from green tea. (6/2057)

Identification of common dietary substances capable of affording protection or modulating the onset and severity of arthritis may have important human health implications. An antioxidant-rich polyphenolic fraction isolated from green tea (green tea polyphenols, GTPs) has been shown to possess anti-inflammatory and anticarcinogenic properties in experimental animals. In this study we determined the effect of oral consumption of GTP on collagen-induced arthritis in mice. In three independent experiments mice given GTP in water exhibited significantly reduced incidence of arthritis (33% to 50%) as compared with mice not given GTP in water (84% to 100%). The arthritis index also was significantly lower in GTP-fed animals. Western blot analysis showed a marked reduction in the expression of inflammatory mediators such as cyclooxygenase 2, IFN-gamma, and tumor necrosis factor alpha in arthritic joints of GTP-fed mice. Histologic and immunohistochemical analysis of the arthritic joints in GTP-fed mice demonstrated only marginal joint infiltration by IFN-gamma and tumor necrosis factor alpha-producing cells as opposed to massive cellular infiltration and fully developed pannus in arthritic joints of non-GTP-fed mice. The neutral endopeptidase activity was approximately 7-fold higher in arthritic joints of non-GTP-fed mice in comparison to nonarthritic joints of unimmunized mice whereas it was only 2-fold higher in the arthritic joints of GTP-fed mice. Additionally, total IgG and type II collagen-specific IgG levels were lower in serum and arthritic joints of GTP-fed mice. Taken together our studies suggest that a polyphenolic fraction from green tea that is rich in antioxidants may be useful in the prevention of onset and severity of arthritis. (+info)

Extended field of view sonography in musculoskeletal imaging. (7/2057)

The usage patterns and benefits of extended field of view sonography were analyzed prospectively in 100 consecutive musculoskeletal ultrasonographic examinations. Extended field of view sonography was used in 23 of 58 abnormal cases (10 of 41 shoulders, five of eight other joints, seven of seven extra-articular extremities, one of two interventional procedures) and two of 42 normal cases. Of 23 abnormal cases using extended field of view sonography (12 of 46 tendon tears and 11 of 12 fluid collections or masses), this modality helped in measuring abnormalities in 13, displaying abnormalities in 19, showing spatial relationships in 17, communicating findings in 13, and making diagnoses in 0. Extended field of view is a useful technique for musculoskeletal ultrasonography. The primary benefits are measuring and displaying abnormalities (most often fluid collections or masses and extra-articular extremity abnormalities). (+info)

GDF5 coordinates bone and joint formation during digit development. (8/2057)

A functional skeletal system requires the coordinated development of many different tissue types, including cartilage, bones, joints, and tendons. Members of the Bone morphogenetic protein (BMP) family of secreted signaling molecules have been implicated as endogenous regulators of skeletal development. This is based on their expression during bone and joint formation, their ability to induce ectopic bone and cartilage, and the skeletal abnormalities present in animals with mutations in BMP family members. One member of this family, Growth/differentiation factor 5 (GDF5), is encoded by the mouse brachypodism locus. Mice with mutations in this gene show reductions in the length of bones in the limbs, altered formation of bones and joints in the sternum, and a reduction in the number of bones in the digits. The expression pattern of Gdf5 during normal development and the phenotypes seen in mice with single or double mutations in Gdf5 and Bmp5 suggested that Gdf5 has multiple functions in skeletogenesis, including roles in joint and cartilage development. To further understand the function of GDF5 in skeletal development, we assayed the response of developing chick and mouse limbs to recombinant GDF5 protein. The results from these assays, coupled with an analysis of the development of brachypodism digits, indicate that GDF5 is necessary and sufficient for both cartilage development and the restriction of joint formation to the appropriate location. Thus, GDF5 function in the digits demonstrates a link between cartilage development and joint development and is an important determinant of the pattern of bones and articulations in the digits. (+info)

1. Osteoarthritis: A degenerative condition that causes the breakdown of cartilage in the joints, leading to pain, stiffness, and loss of mobility.
2. Rheumatoid arthritis: An autoimmune disease that causes inflammation in the joints, leading to pain, swelling, and deformity.
3. Gout: A condition caused by the buildup of uric acid in the joints, leading to sudden and severe attacks of pain, inflammation, and swelling.
4. Bursitis: Inflammation of the bursae, small fluid-filled sacs that cushion the joints and reduce friction between tendons and bones.
5. Tendinitis: Inflammation of the tendons, which connect muscles to bones.
6. Synovitis: Inflammation of the synovial membrane, a thin lining that covers the joints and lubricates them with fluid.
7. Periarthritis: Inflammation of the tissues around the joints, such as the synovial membrane, tendons, and ligaments.
8. Spondyloarthritis: A group of conditions that affect the spine and sacroiliac joints, leading to inflammation and pain in these areas.
9. Juvenile idiopathic arthritis: A condition that affects children and causes inflammation and pain in the joints.
10. Systemic lupus erythematosus: An autoimmune disease that can affect many parts of the body, including the joints.

These are just a few examples of the many types of joint diseases that exist. Each type has its own unique symptoms and causes, and they can be caused by a variety of factors such as genetics, injury, infection, or age-related wear and tear. Treatment options for joint diseases can range from medication and physical therapy to surgery, depending on the severity of the condition and its underlying cause.

There are several types of joint instability, including:

1. Ligamentous laxity: A condition where the ligaments surrounding a joint become stretched or torn, leading to instability.
2. Capsular laxity: A condition where the capsule, a thin layer of connective tissue that surrounds a joint, becomes stretched or torn, leading to instability.
3. Muscular imbalance: A condition where the muscles surrounding a joint are either too weak or too strong, leading to instability.
4. Osteochondral defects: A condition where there is damage to the cartilage and bone within a joint, leading to instability.
5. Post-traumatic instability: A condition that develops after a traumatic injury to a joint, such as a dislocation or fracture.

Joint instability can be caused by various factors, including:

1. Trauma: A sudden and forceful injury to a joint, such as a fall or a blow.
2. Overuse: Repeated stress on a joint, such as from repetitive motion or sports activities.
3. Genetics: Some people may be born with joint instability due to inherited genetic factors.
4. Aging: As we age, our joints can become less stable due to wear and tear on the cartilage and other tissues.
5. Disease: Certain diseases, such as rheumatoid arthritis or osteoarthritis, can cause joint instability.

Symptoms of joint instability may include:

1. Pain: A sharp, aching pain in the affected joint, especially with movement.
2. Stiffness: Limited range of motion and stiffness in the affected joint.
3. Swelling: Swelling and inflammation in the affected joint.
4. Instability: A feeling of looseness or instability in the affected joint.
5. Crepitus: Grinding or crunching sensations in the affected joint.

Treatment for joint instability depends on the underlying cause and may include:

1. Rest and ice: Resting the affected joint and applying ice to reduce pain and swelling.
2. Physical therapy: Strengthening the surrounding muscles to support the joint and improve stability.
3. Bracing: Using a brace or splint to provide support and stability to the affected joint.
4. Medications: Anti-inflammatory medications, such as ibuprofen or naproxen, to reduce pain and inflammation.
5. Surgery: In severe cases, surgery may be necessary to repair or reconstruct the damaged tissues and improve joint stability.

There are several types of TMJ disorders, including:

1. Temporomandibular joint dysfunction syndrome (TMD): This is a common condition that affects the TMJ and the surrounding muscles, causing pain and limited movement in the jaw.
2. Dislocation of the temporomandibular joint (TMJ dislocation): This occurs when the ball and socket of the TMJ become dislocated, leading to pain and limited movement in the jaw.
3. Osteoarthritis of the temporomandibular joint: This is a condition where the cartilage that covers the bones of the TMJ wears down over time, causing pain and stiffness in the jaw.
4. Internal derangement of the temporomandibular joint: This occurs when the disc or meniscus of the TMJ becomes displaced or dislocated, leading to pain and limited movement in the jaw.
5. Temporomandibular joint degenerative changes: This is a condition where the cartilage and bone of the TMJ wear down over time, causing pain and stiffness in the jaw.

TMJ disorders can be caused by a variety of factors, including injury to the jaw, misalignment of the teeth, or excessive clenching or grinding of the teeth. Symptoms of TMJ disorders may include pain in the jaw, face, or neck, limited movement of the jaw, difficulty chewing or speaking, and clicking or popping sounds when opening or closing the mouth.

Treatment for TMJ disorders can vary depending on the severity of the condition and may include self-care measures such as jaw exercises, heat or cold therapy, and pain relief medications. In some cases, dental splints or occlusal adjustments may be recommended to help align the teeth and reduce pressure on the TMJ. Surgery may be considered in severe cases where other treatments have been unsuccessful.

It is important to seek medical attention if you experience persistent pain or difficulty with jaw movement, as early diagnosis and treatment can help prevent long-term complications and improve quality of life.

The exact cause of osteoarthritis is not known, but it is thought to be due to a combination of factors such as genetics, wear and tear on joints over time, and injuries or trauma to the joint. Osteoarthritis can affect any joint in the body, but it most commonly affects the hands, knees, hips, and spine.

The symptoms of osteoarthritis can vary depending on the severity of the condition and which joint is affected. Common symptoms include:

* Pain or tenderness in the joint
* Stiffness, especially after periods of rest or inactivity
* Limited mobility or loss of flexibility
* Grating or crackling sensations when the joint is moved
* Swelling or redness in the affected joint
* Muscle weakness or wasting

There is no cure for osteoarthritis, but there are several treatment options available to manage the symptoms and slow the progression of the disease. These include:

* Pain relief medications such as acetaminophen or nonsteroidal anti-inflammatory drugs (NSAIDs)
* Physical therapy to improve mobility and strength
* Lifestyle modifications such as weight loss, regular exercise, and avoiding activities that exacerbate the condition
* Bracing or orthotics to support the affected joint
* Corticosteroid injections or hyaluronic acid injections to reduce inflammation and improve joint function
* Joint replacement surgery in severe cases where other treatments have failed.

Early diagnosis and treatment of osteoarthritis can help manage symptoms, slow the progression of the disease, and improve quality of life for individuals with this condition.

There are several symptoms of RA, including:

1. Joint pain and stiffness, especially in the hands and feet
2. Swollen and warm joints
3. Redness and tenderness in the affected areas
4. Fatigue, fever, and loss of appetite
5. Loss of range of motion in the affected joints
6. Firm bumps of tissue under the skin (rheumatoid nodules)

RA can be diagnosed through a combination of physical examination, medical history, blood tests, and imaging studies such as X-rays or ultrasound. Treatment typically involves a combination of medications, including nonsteroidal anti-inflammatory drugs (NSAIDs), disease-modifying anti-rheumatic drugs (DMARDs), and biologic agents. Lifestyle modifications such as exercise and physical therapy can also be helpful in managing symptoms and improving quality of life.

There is no cure for RA, but early diagnosis and aggressive treatment can help to slow the progression of the disease and reduce symptoms. With proper management, many people with RA are able to lead active and fulfilling lives.

There are several possible causes of synovitis, including:

1. Infection: Bacterial, viral, or fungal infections can cause synovitis.
2. Autoimmune disorders: Conditions such as rheumatoid arthritis, psoriatic arthritis, and gout can cause chronic synovitis.
3. Overuse injuries: Repetitive strain injuries, such as those caused by repetitive jumping or throwing, can lead to synovitis in the affected joint.
4. Trauma: A sudden injury, such as a fall or a blow to the joint, can cause acute synovitis.

Symptoms of synovitis may include:

1. Pain: Pain is the most common symptom of synovitis, and it can range from mild to severe.
2. Swelling: The affected joint or limb may become swollen and warm to the touch.
3. Limited range of motion: Synovitis can cause stiffness and limited mobility in the affected joint.
4. Redness: The affected area may become red and inflamed.
5. Fever: In some cases, synovitis may be accompanied by a fever.

Treatment for synovitis depends on the underlying cause and the severity of the condition. Conservative treatments such as rest, physical therapy, and anti-inflammatory medications are often effective in managing mild to moderate cases of synovitis. In more severe cases, surgical intervention may be necessary.

In conclusion, synovitis is a common condition that can cause pain and limited mobility in the affected joint or limb. It is important to seek medical attention if symptoms persist or worsen over time, as early diagnosis and treatment can help to prevent long-term damage and improve outcomes.

These animal models allow researchers to study the underlying causes of arthritis, test new treatments and therapies, and evaluate their effectiveness in a controlled environment before moving to human clinical trials. Experimental arthritis models are used to investigate various aspects of the disease, including its pathophysiology, immunogenicity, and potential therapeutic targets.

Some common experimental arthritis models include:

1. Collagen-induced arthritis (CIA): This model is induced in mice by immunizing them with type II collagen, which leads to an autoimmune response and inflammation in the joints.
2. Rheumatoid arthritis (RA) models: These models are developed by transferring cells from RA patients into immunodeficient mice, which then develop arthritis-like symptoms.
3. Osteoarthritis (OA) models: These models are induced in animals by subjecting them to joint injury or overuse, which leads to degenerative changes in the joints and bone.
4. Psoriatic arthritis (PsA) models: These models are developed by inducing psoriasis in mice, which then develop arthritis-like symptoms.

Experimental arthritis models have contributed significantly to our understanding of the disease and have helped to identify potential therapeutic targets for the treatment of arthritis. However, it is important to note that these models are not perfect representations of human arthritis and should be used as tools to complement, rather than replace, human clinical trials.

A type of arthritis that is caused by an infection in the joint, typically bacterial or viral. The most common form of infectious arthritis is Lyme disease, which is caused by the bacterium Borrelia burgdorferi and is transmitted through the bite of an infected blacklegged tick. Other types of infectious arthritis include septic arthritis (caused by bacterial infection) and reactive arthritis (caused by a bacterial or viral infection in another part of the body).

Symptoms: Pain, swelling, redness, warmth, and limited range of motion in the affected joint. Fever may also be present.

Diagnosis: A diagnosis is made based on symptoms, physical examination, blood tests (such as a complete blood count or a polymerase chain reaction test to detect the presence of bacteria or viruses), and imaging studies (such as X-rays or ultrasound).

Treatment: Treatment typically involves antibiotics to eradicate the infection, as well as medication to manage symptoms such as pain and inflammation. In severe cases, surgery may be necessary to repair damaged tissue or joints.

The risk of developing osteoarthritis of the knee increases with age, obesity, and previous knee injuries or surgery. Symptoms of knee OA can include:

* Pain and stiffness in the knee, especially after activity or extended periods of standing or sitting
* Swelling and redness in the knee
* Difficulty moving the knee through its full range of motion
* Crunching or grinding sensations when the knee is bent or straightened
* Instability or a feeling that the knee may give way

Treatment for knee OA typically includes a combination of medication, physical therapy, and lifestyle modifications. Medications such as pain relievers, anti-inflammatory drugs, and corticosteroids can help manage symptoms, while physical therapy can improve joint mobility and strength. Lifestyle modifications, such as weight loss, regular exercise, and avoiding activities that exacerbate the condition, can also help slow the progression of the disease. In severe cases, surgery may be necessary to repair or replace the damaged joint.

The word "arthralgia" comes from the Greek words "arthron," meaning joint, and "algos," meaning pain. It is often used interchangeably with the term "joint pain," but arthralgia specifically refers to a type of pain that is not caused by inflammation or injury.

Arthralgia can manifest in different ways, including:

1. Aching or dull pain in one or more joints
2. Sharp or stabbing pain in one or more joints
3. Pain that worsens with movement or weight-bearing activity
4. Pain that improves with rest
5. Pain that is localized to one joint or multiple joints
6. Pain that is accompanied by stiffness or limited range of motion
7. Pain that is worse in the morning or after periods of rest
8. Pain that is triggered by certain activities or movements

The diagnosis of arthralgia typically involves a comprehensive medical history and physical examination, as well as diagnostic tests such as X-rays, blood tests, or imaging studies. Treatment for arthralgia depends on the underlying cause and may include medications, lifestyle modifications, or other interventions.

Dislocation is a term used in medicine to describe the displacement of a bone or joint from its normal position, often due to injury or disease. This can cause pain, limited mobility, and potentially lead to long-term complications if left untreated.

There are several types of dislocations that can occur in different parts of the body, including:

1. Shoulder dislocation: The upper arm bone (humerus) is forced out of the shoulder socket.
2. Hip dislocation: The femur (thigh bone) is forced out of the hip socket.
3. Knee dislocation: The kneecap (patella) is forced out of its normal position in the knee joint.
4. Ankle dislocation: The bones of the ankle are forced out of their normal position.
5. Elbow dislocation: The humerus is forced out of the elbow joint.
6. Wrist dislocation: The bones of the wrist are forced out of their normal position.
7. Finger dislocation: One or more of the bones in a finger are forced out of their normal position.
8. Temporomandibular joint (TMJ) dislocation: The jawbone is forced out of its normal position, which can cause pain and difficulty opening the mouth.

Dislocations can be caused by a variety of factors, including sports injuries, car accidents, falls, and certain medical conditions such as osteoporosis or degenerative joint disease. Treatment for dislocations often involves reducing the displaced bone or joint back into its normal position, either through manual manipulation or surgery. In some cases, physical therapy may be necessary to help restore strength and range of motion in the affected area.

TMJD can be caused by a variety of factors, including injury to the joint, misalignment of the teeth, or excessive stress on the jaw. Treatment options for TMJD include pain relievers, physical therapy, and dental splints or mouth guards. In severe cases, surgery may be necessary.

The term "TMJD" was first coined in the medical literature in the 1970s, and since then it has been widely used by healthcare providers to describe this condition. However, some researchers argue that the term is too broad and encompasses a variety of different conditions, and suggest that it be replaced with more specific terms such as "temporomandibular joint disorder" or "TMJ osteoarthritis."

There are different types of contractures, including:

1. Scar contracture: This type of contracture occurs when a scar tissue forms and tightens, causing a loss of movement in the affected area.
2. Neurogenic contracture: This type of contracture is caused by nerve damage and can occur after an injury or surgery.
3. Post-burn contracture: This type of contracture occurs after a burn injury and is caused by scarring and tightening of the skin and underlying tissues.
4. Congenital contracture: This type of contracture is present at birth and can be caused by genetic or environmental factors.

Signs and symptoms of contractures may include:

1. Limited range of motion
2. Pain or stiffness in the affected area
3. Skin tightening or shrinkage
4. Deformity of the affected area

Treatment options for contractures depend on the severity and cause of the condition, and may include:

1. Physical therapy to improve range of motion and strength
2. Bracing to support the affected area and prevent further tightening
3. Surgery to release or lengthen the scar tissue or tendons
4. Injections of botulinum toxin or other medications to relax the muscle and improve range of motion.

The symptoms of ankylosis may include pain, stiffness, limited range of motion, and difficulty moving the affected joint. In severe cases, ankylosis can lead to a complete loss of mobility and flexibility in the affected joint, causing significant disability and impacting daily activities.

Treatment for ankylosis depends on the underlying cause and the severity of the condition. Conservative management may include physical therapy, pain medication, and lifestyle modifications, while surgical intervention may be necessary in severe cases to relieve pressure on nerves or realign the bones. In some cases, ankylosis may be a chronic condition that requires ongoing management and monitoring to manage symptoms and prevent complications.

There are several types of prosthesis-related infections, including:

1. Bacterial infections: These are the most common type of prosthesis-related infection and can occur around any type of implanted device. They are caused by bacteria that enter the body through a surgical incision or other opening.
2. Fungal infections: These types of infections are less common and typically occur in individuals who have a weakened immune system or who have been taking antibiotics for another infection.
3. Viral infections: These infections can occur around implanted devices, such as pacemakers, and are caused by viruses that enter the body through a surgical incision or other opening.
4. Parasitic infections: These types of infections are rare and occur when parasites, such as tapeworms, infect the implanted device or the surrounding tissue.

Prosthesis-related infections can cause a range of symptoms, including pain, swelling, redness, warmth, and fever. In severe cases, these infections can lead to sepsis, a potentially life-threatening condition that occurs when bacteria or other microorganisms enter the bloodstream.

Prosthesis-related infections are typically diagnosed through a combination of physical examination, imaging tests such as X-rays or CT scans, and laboratory tests to identify the type of microorganism causing the infection. Treatment typically involves antibiotics or other antimicrobial agents to eliminate the infection, and may also involve surgical removal of the infected implant.

Prevention is key in avoiding prosthesis-related infections. This includes proper wound care after surgery, keeping the surgical site clean and dry, and taking antibiotics as directed by your healthcare provider to prevent infection. Additionally, it is important to follow your healthcare provider's instructions for caring for your prosthesis, such as regularly cleaning and disinfecting the device and avoiding certain activities that may put excessive stress on the implant.

Overall, while prosthesis-related infections can be serious, prompt diagnosis and appropriate treatment can help to effectively manage these complications and prevent long-term damage or loss of function. It is important to work closely with your healthcare provider to monitor for signs of infection and take steps to prevent and manage any potential complications associated with your prosthesis.

Word in the news:

A recent study published in The Journal of Bone & Joint Surgery found that hemarthrosis is a common complication of knee replacement surgery, occurring in up to 20% of patients. Researchers recommend that patients be carefully monitored for signs of hemarthrosis after surgery and receive prompt treatment to minimize the risk of long-term joint damage.

Osteophytes can take many different forms, depending on the location and severity of the condition that is causing them. They may be small and pointed, or large and flat, and they can vary in color from yellow to red to black. In some cases, osteophytes may be covered with cartilage or other soft tissue.

Osteophytes are often painful and can interfere with joint movement and function. They may also cause inflammation and swelling in the affected area. In severe cases, osteophytes can lead to further complications such as bone fragments breaking off and causing damage to surrounding tissues or nerves.

Treatment for osteophytes usually involves managing the underlying condition that is causing them. This may include medications to reduce inflammation and pain, physical therapy to improve joint mobility and strength, or surgery to repair or replace damaged joints. In some cases, osteophytes may be removed surgically to relieve symptoms and improve joint function.

In summary, osteophyte is a term used to describe bony outgrowths that form on the surface of bones, typically in the joints. These growths can cause pain and interfere with joint movement and function, and may be associated with conditions such as osteoarthritis or rheumatoid arthritis. Treatment usually involves managing the underlying condition and may include medication, physical therapy, or surgery.

There are five types of PsA:

1. Asymptomatic psoriatic arthritis - This type of psoriatic arthritis does not cause any symptoms and is typically diagnosed during routine blood tests or imaging studies.

2. Symptomatic psoriatic arthritis - This type of psoriatic arthritis causes painful joints, stiffness, and swelling in the hands and feet.

3. Distal interphalangeal predominant psoriatic arthritis - This type of psoriatic arthritis affects the joints at the tips of the fingers and toes.

4. Polyarticular psoriatic arthritis - This type of psoriatic arthritis causes inflammation in multiple joints throughout the body, including the hands, feet, knees, elbows, and spine.

5. Sulfur-shoulder psoriatic arthritis - This type of psoriatic arthritis primarily affects the shoulders and upper back.

Symptoms of PsA may include:

1. Joint pain and stiffness

2. Swollen and warm joints

3. Redness and warmth in the affected area

4. Fatigue

5. Low-grade fever

6. Loss of range of motion

7. Skin rashes or lesions

PsA is diagnosed based on a combination of physical examination, medical history, and laboratory tests such as blood tests to check for inflammatory markers (e.g., ESR and CRP) and X-rays or imaging studies to assess joint damage. There is no cure for PsA, but various treatments can help manage symptoms, slow the progression of the disease, and improve quality of life. These may include medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and disease-modifying anti-rheumatic drugs (DMARDs) or biologic agents that target specific proteins involved in inflammation. In severe cases, surgery may be necessary to repair damaged joints or correct deformities.

It's important for people with PsA to work closely with their healthcare provider to develop a personalized treatment plan that addresses their individual needs and monitors their disease activity over time. With appropriate treatment and self-care, many people with PsA are able to manage their symptoms, maintain joint function, and lead active and fulfilling lives.

In conclusion, psoriatic arthritis (PsA) is a chronic inflammatory disease that affects both the skin and joints, causing pain, stiffness, and swelling in various parts of the body. Early diagnosis and appropriate treatment can help manage symptoms, slow the progression of the disease, and improve quality of life.

Some common types of cartilage diseases include:

1. Osteoarthritis: A degenerative condition that causes the breakdown of joint cartilage and bone damage.
2. Rheumatoid arthritis: An autoimmune disease that causes inflammation and pain in the joints, including the cartilage.
3. Cartilage tears: Tears in the cartilage of a joint can cause pain, stiffness, and limited mobility.
4. Cartilage thinning: A condition where the cartilage becomes thinner over time, leading to joint pain and stiffness.
5. Chondrocalcinosis: A condition where calcium deposits form in the cartilage, causing pain and stiffness in the affected joint.
6. Chondromalacia patellae: A condition where the cartilage on the underside of the kneecap deteriorates, leading to pain and instability in the knee joint.
7. Osteochondritis dissecans: A condition where a piece of cartilage and bone becomes detached from the joint surface, causing pain and stiffness.
8. Paget's disease of bone: A condition where the bones become enlarged and deformed due to abnormal bone growth, which can affect the cartilage.
9. Bone spurs: Bony outgrowths that can form in response to injury or inflammation, and can cause pain and limited mobility.
10. Avascular necrosis: A condition where the blood supply to a bone is disrupted, leading to bone death and cartilage damage.

These are just a few examples of cartilage diseases. There are many other conditions that can affect the cartilage in different parts of the body. Treatment options for cartilage diseases vary depending on the specific condition and its severity, but may include medication, physical therapy, or surgery.

There are several different types of pain, including:

1. Acute pain: This type of pain is sudden and severe, and it usually lasts for a short period of time. It can be caused by injuries, surgery, or other forms of tissue damage.
2. Chronic pain: This type of pain persists over a long period of time, often lasting more than 3 months. It can be caused by conditions such as arthritis, fibromyalgia, or nerve damage.
3. Neuropathic pain: This type of pain results from damage to the nervous system, and it can be characterized by burning, shooting, or stabbing sensations.
4. Visceral pain: This type of pain originates in the internal organs, and it can be difficult to localize.
5. Psychogenic pain: This type of pain is caused by psychological factors such as stress, anxiety, or depression.

The medical field uses a range of methods to assess and manage pain, including:

1. Pain rating scales: These are numerical scales that patients use to rate the intensity of their pain.
2. Pain diaries: These are records that patients keep to track their pain over time.
3. Clinical interviews: Healthcare providers use these to gather information about the patient's pain experience and other relevant symptoms.
4. Physical examination: This can help healthcare providers identify any underlying causes of pain, such as injuries or inflammation.
5. Imaging studies: These can be used to visualize the body and identify any structural abnormalities that may be contributing to the patient's pain.
6. Medications: There are a wide range of medications available to treat pain, including analgesics, nonsteroidal anti-inflammatory drugs (NSAIDs), and muscle relaxants.
7. Alternative therapies: These can include acupuncture, massage, and physical therapy.
8. Interventional procedures: These are minimally invasive procedures that can be used to treat pain, such as nerve blocks and spinal cord stimulation.

It is important for healthcare providers to approach pain management with a multi-modal approach, using a combination of these methods to address the physical, emotional, and social aspects of pain. By doing so, they can help improve the patient's quality of life and reduce their suffering.

1. Meniscal tears: The meniscus is a cartilage structure in the knee joint that can tear due to twisting or bending movements.
2. Ligament sprains: The ligaments that connect the bones of the knee joint can become stretched or torn, leading to instability and pain.
3. Torn cartilage: The articular cartilage that covers the ends of the bones in the knee joint can tear due to wear and tear or trauma.
4. Fractures: The bones of the knee joint can fracture as a result of a direct blow or fall.
5. Dislocations: The bones of the knee joint can become dislocated, causing pain and instability.
6. Patellar tendinitis: Inflammation of the tendon that connects the patella (kneecap) to the shinbone.
7. Iliotibial band syndrome: Inflammation of the iliotibial band, a ligament that runs down the outside of the thigh and crosses the knee joint.
8. Osteochondritis dissecans: A condition in which a piece of cartilage and bone becomes detached from the end of a bone in the knee joint.
9. Baker's cyst: A fluid-filled cyst that forms behind the knee, usually as a result of a tear in the meniscus or a knee injury.

Symptoms of knee injuries can include pain, swelling, stiffness, and limited mobility. Treatment for knee injuries depends on the severity of the injury and may range from conservative measures such as physical therapy and medication to surgical intervention.

Chondrocalcinosis is a type of calcifying disorder, which is a group of conditions characterized by the deposition of minerals such as calcium and phosphate in soft tissues. This condition can affect various joints in the body, including the hips, knees, shoulders, and elbows.

In this article, we will explore the definition, causes, symptoms, diagnosis, treatment, and prognosis of chondrocalcinosis. We will also discuss the surgical procedures used to treat this condition and the potential complications that can arise.

Definition of Chondrocalcinosis:

Chondrocalcinosis is a medical term that refers to the deposition of calcium pyrophosphate crystals within cartilage. This condition is also known as chondromalacia or calcifying joint disease. It is a type of calcifying disorder, which affects the cartilage in various joints throughout the body.

Causes of Chondrocalcinosis:

The exact cause of chondrocalcinosis is not fully understood, but it is believed to be related to aging, genetics, and certain medical conditions. Some risk factors for developing chondrocalcinosis include:

Age: The risk of developing chondrocalcinosis increases with age, with most cases occurring in people over the age of 50.

Family history: People with a family history of chondrocalcinosis are more likely to develop the condition.

Rheumatoid arthritis or osteoarthritis: These conditions can increase the risk of developing chondrocalcinosis.

Other medical conditions: Certain medical conditions, such as hypothyroidism and hyperparathyroidism, can increase the risk of developing chondrocalcinosis.

Symptoms of Chondrocalcinosis:

The symptoms of chondrocalcinosis can vary depending on the severity of the condition and the joints affected. Common symptoms include:

Pain: Pain is one of the most common symptoms of chondrocalcinosis, particularly in the affected joint.

Stiffness: Joint stiffness and limited range of motion can also occur as a result of chondrocalcinosis.

Swelling: Swelling in the affected joint is another common symptom of chondrocalcinosis.

Redness: The affected joint may become red and warm to the touch due to inflammation.

Crepitus: Crepitus, or a grinding sensation, may be felt in the affected joint as a result of the calcium pyrophosphate crystals rubbing against each other.

Treatment of Chondrocalcinosis:

There is no cure for chondrocalcinosis, but there are several treatment options available to manage the symptoms and slow down the progression of the condition. These may include:

Pain relief medication: Over-the-counter pain relievers such as acetaminophen or nonsteroidal anti-inflammatory drugs (NSAIDs) can help alleviate pain and reduce inflammation.

Physical therapy: Gentle exercises and stretches can help maintain joint mobility and strength.

Joint injections: Injecting corticosteroids or hyaluronic acid into the affected joint can help reduce inflammation and relieve pain.

Surgery: In severe cases of chondrocalcinosis, surgery may be necessary to remove the calcium pyrophosphate crystals or repair damaged tissue.

Prevention of Chondrocalcinosis:

There is no guaranteed way to prevent chondrocalcinosis, but there are several measures that can help reduce the risk of developing the condition. These may include:

Maintaining a healthy weight: Excessive weight can put additional strain on the joints and increase the risk of developing chondrocalcinosis.

Staying active: Regular exercise can help maintain joint mobility and strength, reducing the risk of developing chondrocalcinosis.

Wearing protective gear: Wearing protective gear such as knee pads or elbow pads when engaging in activities that involve repetitive stress on the joints can help reduce the risk of developing chondrocalcinosis.

Avoiding excessive stress on the joints: Avoiding activities that involve repetitive stress on the joints, such as heavy lifting or bending, can help reduce the risk of developing chondrocalcinosis.

Early diagnosis and treatment of chondrocalcinosis can help manage symptoms and slow down the progression of the condition. If you suspect you may have chondrocalcinosis, it is important to consult with a healthcare professional for proper evaluation and treatment.

In medicine, cadavers are used for a variety of purposes, such as:

1. Anatomy education: Medical students and residents learn about the human body by studying and dissecting cadavers. This helps them develop a deeper understanding of human anatomy and improves their surgical skills.
2. Research: Cadavers are used in scientific research to study the effects of diseases, injuries, and treatments on the human body. This helps scientists develop new medical techniques and therapies.
3. Forensic analysis: Cadavers can be used to aid in the investigation of crimes and accidents. By examining the body and its injuries, forensic experts can determine cause of death, identify suspects, and reconstruct events.
4. Organ donation: After death, cadavers can be used to harvest organs and tissues for transplantation into living patients. This can improve the quality of life for those with organ failure or other medical conditions.
5. Medical training simulations: Cadavers can be used to simulate real-life medical scenarios, allowing healthcare professionals to practice their skills in a controlled environment.

In summary, the term "cadaver" refers to the body of a deceased person and is used in the medical field for various purposes, including anatomy education, research, forensic analysis, organ donation, and medical training simulations.

Disease progression can be classified into several types based on the pattern of worsening:

1. Chronic progressive disease: In this type, the disease worsens steadily over time, with a gradual increase in symptoms and decline in function. Examples include rheumatoid arthritis, osteoarthritis, and Parkinson's disease.
2. Acute progressive disease: This type of disease worsens rapidly over a short period, often followed by periods of stability. Examples include sepsis, acute myocardial infarction (heart attack), and stroke.
3. Cyclical disease: In this type, the disease follows a cycle of worsening and improvement, with periodic exacerbations and remissions. Examples include multiple sclerosis, lupus, and rheumatoid arthritis.
4. Recurrent disease: This type is characterized by episodes of worsening followed by periods of recovery. Examples include migraine headaches, asthma, and appendicitis.
5. Catastrophic disease: In this type, the disease progresses rapidly and unpredictably, with a poor prognosis. Examples include cancer, AIDS, and organ failure.

Disease progression can be influenced by various factors, including:

1. Genetics: Some diseases are inherited and may have a predetermined course of progression.
2. Lifestyle: Factors such as smoking, lack of exercise, and poor diet can contribute to disease progression.
3. Environmental factors: Exposure to toxins, allergens, and other environmental stressors can influence disease progression.
4. Medical treatment: The effectiveness of medical treatment can impact disease progression, either by slowing or halting the disease process or by causing unintended side effects.
5. Co-morbidities: The presence of multiple diseases or conditions can interact and affect each other's progression.

Understanding the type and factors influencing disease progression is essential for developing effective treatment plans and improving patient outcomes.

Types of Finger Injuries
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1. Cuts and Lacerations: These are the most common type of finger injury and can occur when the skin is cut or torn due to a sharp object or blunt force.
2. Sprains and Strains: These injuries occur when the ligaments or muscles in the fingers are stretched or torn, causing pain and swelling.
3. Fractures: Finger fractures can occur when the bones in the finger are broken due to a direct blow or crushing force.
4. Dislocations: This occurs when the bones in the finger are forced out of their normal position.
5. Tendon Injuries: Tendons connect muscles to bones and can become injured due to overuse or sudden strain.
6. Nerve Injuries: Finger injuries can also affect the nerves, causing numbness, tingling, or pain in the fingers.

Causes of Finger Injuries
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1. Accidents: Car accidents, falls, and other accidents can cause finger injuries.
2. Sports: Contact sports such as basketball, football, and hockey can lead to finger injuries due to collisions or falls.
3. Work-related Activities: Jobs that involve manual labor or heavy machinery can increase the risk of finger injuries.
4. Overuse: Repetitive movements or overuse of the fingers can lead to injuries such as tendonitis or sprains.
5. Medical Conditions: Certain medical conditions such as arthritis, gout, and diabetes can increase the risk of finger injuries.

Symptoms of Finger Injuries
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1. Pain: Pain is the most common symptom of finger injuries, ranging from mild to severe.
2. Swelling: Swelling in the affected finger or fingers can occur due to inflammation or bruising.
3. Limited Mobility: Finger injuries can limit mobility and make it difficult to move the fingers or perform everyday activities.
4. Deformity: In severe cases, finger injuries can cause deformities such as bone misalignment or muscle imbalance.
5. Numbness or Tingling: Finger injuries can cause numbness or tingling sensations in the affected fingers.

Treatment of Finger Injuries
-------------------------

1. Rest: Resting the injured finger and avoiding activities that exacerbate the injury is essential for recovery.
2. Ice: Applying ice to the affected area can reduce swelling and relieve pain.
3. Compression: Wrapping the injured finger with a bandage or compression glove can help reduce swelling and stabilize the joints.
4. Elevation: Elevating the injured hand above heart level can reduce swelling and promote healing.
5. Medications: Over-the-counter pain medications such as ibuprofen or acetaminophen can relieve pain and reduce inflammation.
6. Immobilization: Immobilizing the injured finger with a splint or cast can help promote healing and prevent further injury.
7. Physical Therapy: Gentle exercises and stretches can help improve mobility and strength in the affected finger.
8. Surgery: In severe cases, surgery may be necessary to repair damaged tissues or realign bones.

Prevention of Finger Injuries
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1. Warm-up Exercises: Performing warm-up exercises before engaging in physical activities can help prevent finger injuries by increasing blood flow and flexibility.
2. Proper Equipment: Using proper equipment such as gloves or protective gear can help prevent finger injuries, especially in sports or high-risk activities.
3. Careful Lifting: Lifting objects with proper technique and using the legs instead of the fingers can help prevent strains and sprains.
4. Finger Stretching: Regular stretching exercises can help improve flexibility and reduce the risk of finger injuries.
5. Strengthening Exercises: Strengthening the muscles in the hand and fingers through exercises such as grip strengthening can help prevent injuries.
6. Avoiding Overuse: Taking regular breaks and avoiding overuse can help prevent fatigue and reduce the risk of finger injuries.

Some common types of bone diseases include:

1. Osteoporosis: A condition characterized by brittle, porous bones that are prone to fracture.
2. Osteoarthritis: A degenerative joint disease that causes pain and stiffness in the joints.
3. Rheumatoid arthritis: An autoimmune disorder that causes inflammation and pain in the joints.
4. Bone cancer: A malignant tumor that develops in the bones.
5. Paget's disease of bone: A condition characterized by abnormal bone growth and deformity.
6. Osteogenesis imperfecta: A genetic disorder that affects the formation of bone and can cause brittle bones and other skeletal deformities.
7. Fibrous dysplasia: A rare condition characterized by abnormal growth and development of bone tissue.
8. Multiple myeloma: A type of cancer that affects the plasma cells in the bone marrow.
9. Bone cysts: Fluid-filled cavities that can form in the bones and cause pain, weakness, and deformity.
10. Bone spurs: Abnormal growths of bone that can form along the edges of joints and cause pain and stiffness.

Bone diseases can be diagnosed through a variety of tests, including X-rays, CT scans, MRI scans, and bone biopsies. Treatment options vary depending on the specific disease and can include medication, surgery, or a combination of both.

There are several types of JA, including:

1. Systemic juvenile idiopathic arthritis (SJIA): A severe form of JA that affects the entire body, causing fever, rash, and swollen lymph nodes in addition to joint inflammation.
2. Polyarticular juvenile idiopathic arthritis (PJIA): A common form of JA that affects multiple joints, especially in the hands and feet.
3. Oligoarticular juvenile idiopathic arthritis (OJIA): A mild form of JA that affects only a few joints.
4. Juvenile psoriatic arthritis (JPsA): A type of JA that is associated with psoriasis, a skin condition characterized by red, scaly patches.
5. Enthesitis-related juvenile idiopathic arthritis (ER-JIA): A rare form of JA that affects the areas where tendons and ligaments attach to bones.
6. Undifferentiated arthritis: A type of JA that does not fit into any of the other categories.

The symptoms of JA can vary depending on the specific type and severity of the condition, but may include:

* Joint pain and stiffness
* Swelling and redness in the affected joints
* Fatigue and fever
* Loss of mobility and range of motion
* Difficulty walking or standing

The exact cause of JA is not known, but it is believed to involve a combination of genetic and environmental factors. There is no cure for JA, but treatment options are available to help manage symptoms and prevent long-term joint damage. These may include medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) and disease-modifying anti-rheumatic drugs (DMARDs), as well as physical therapy and lifestyle modifications.

Osteoarticular tuberculosis is typically diagnosed through a combination of physical examination, imaging studies such as X-rays or CT scans, and laboratory tests to detect the presence of Mycobacterium tuberculosis infection. Treatment typically involves a course of antibiotics for a period of at least six months, and surgical intervention may be necessary in some cases.

Preventive measures for osteoarticular tuberculosis include vaccination against tuberculosis, screening for the disease in high-risk populations such as those with weakened immune systems, and avoiding close contact with individuals who have active tuberculosis infections.

Some of the key features of osteoarticular tuberculosis include:

* Pain and swelling in the affected joint
* Limited mobility in the joint
* Fever, fatigue, and weight loss
* Night sweats and loss of appetite
* Presence of Mycobacterium tuberculosis infection in the joint fluid or tissue.

Osteoarticular tuberculosis can be challenging to diagnose and treat, as it may mimic other conditions such as osteoarthritis or rheumatoid arthritis. However, early detection and appropriate treatment can help prevent long-term joint damage and improve outcomes for patients with this condition.

Overall, osteoarticular tuberculosis is a serious form of tuberculosis that affects the bones and joints, causing pain, swelling, and limited mobility. Prompt diagnosis and treatment are essential to prevent long-term damage and improve outcomes for patients with this condition.

Examples of infectious bone diseases include:

1. Osteomyelitis: This is a bacterial infection of the bone that can cause pain, swelling, and fever. It can be caused by a variety of bacteria, including Staphylococcus aureus and Streptococcus pneumoniae.
2. Bacterial arthritis: This is an infection of the joints that can cause pain, swelling, and stiffness. It is often caused by bacteria such as Streptococcus pyogenes.
3. Tuberculosis: This is a bacterial infection caused by Mycobacterium tuberculosis that primarily affects the lungs but can also affect the bones.
4. Pyogenic infections: These are infections caused by Pus-forming bacteria such as Staphylococcus aureus, which can cause osteomyelitis and other bone infections.
5. Fungal infections: These are infections caused by fungi such as Aspergillus or Candida that can infect the bones and cause pain, swelling, and difficulty moving the affected area.
6. Viral infections: Some viral infections such as HIV, HTLV-1, and HTLV-2 can cause bone infections like osteomyelitis.
7. Mycobacterial infections: These are infections caused by Mycobacterium tuberculosis that primarily affects the lungs but can also affect the bones.
8. Lyme disease: This is a bacterial infection caused by Borrelia burgdorferi that can cause pain, swelling, and difficulty moving the affected area.
9. Endometriosis: This is a condition where tissue similar to the lining of the uterus grows outside the uterus and can cause pain, inflammation, and bone damage.
10. Bone cancer: This is a malignant tumor that develops in the bones and can cause pain, swelling, and difficulty moving the affected area.

These are just some of the possible causes of bone pain, and it's essential to consult with a healthcare professional for proper diagnosis and treatment.

There are several types of osteochondrosis, including:

1. Osteoarthritis: A degenerative condition where the cartilage in the joint wears down over time, leading to bone-on-bone contact and pain.
2. Osteochondritis dissecans: A condition where a piece of cartilage or bone within the joint becomes detached, causing pain and stiffness.
3. Osteochondral lesions: Localized areas of damage to the cartilage and/or bone within the joint, often caused by injury or repetitive strain.
4. Osteochondritis dissecans of the talus: A condition specific to the ankle joint, where a piece of cartilage and bone becomes detached, causing pain and stiffness.

Treatment for osteochondrosis depends on the severity and location of the condition, and may include physical therapy, medication, or in some cases, surgery. It is important to seek medical attention if symptoms persist or worsen over time, as untreated osteochondrosis can lead to further joint damage and decreased mobility.

1) They share similarities with humans: Many animal species share similar biological and physiological characteristics with humans, making them useful for studying human diseases. For example, mice and rats are often used to study diseases such as diabetes, heart disease, and cancer because they have similar metabolic and cardiovascular systems to humans.

2) They can be genetically manipulated: Animal disease models can be genetically engineered to develop specific diseases or to model human genetic disorders. This allows researchers to study the progression of the disease and test potential treatments in a controlled environment.

3) They can be used to test drugs and therapies: Before new drugs or therapies are tested in humans, they are often first tested in animal models of disease. This allows researchers to assess the safety and efficacy of the treatment before moving on to human clinical trials.

4) They can provide insights into disease mechanisms: Studying disease models in animals can provide valuable insights into the underlying mechanisms of a particular disease. This information can then be used to develop new treatments or improve existing ones.

5) Reduces the need for human testing: Using animal disease models reduces the need for human testing, which can be time-consuming, expensive, and ethically challenging. However, it is important to note that animal models are not perfect substitutes for human subjects, and results obtained from animal studies may not always translate to humans.

6) They can be used to study infectious diseases: Animal disease models can be used to study infectious diseases such as HIV, TB, and malaria. These models allow researchers to understand how the disease is transmitted, how it progresses, and how it responds to treatment.

7) They can be used to study complex diseases: Animal disease models can be used to study complex diseases such as cancer, diabetes, and heart disease. These models allow researchers to understand the underlying mechanisms of the disease and test potential treatments.

8) They are cost-effective: Animal disease models are often less expensive than human clinical trials, making them a cost-effective way to conduct research.

9) They can be used to study drug delivery: Animal disease models can be used to study drug delivery and pharmacokinetics, which is important for developing new drugs and drug delivery systems.

10) They can be used to study aging: Animal disease models can be used to study the aging process and age-related diseases such as Alzheimer's and Parkinson's. This allows researchers to understand how aging contributes to disease and develop potential treatments.

* Headaches or migraines
* Dental problems (e.g., toothache, abscess)
* Sinusitis
* Eye problems (e.g., conjunctivitis, styes)
* Infections (e.g., colds, flu)
* Allergies
* Injuries or trauma
* Neurological disorders (e.g., trigeminal neuralgia, Bell's palsy)
* Cancer

The types of facial pain include:

* Constant pain: Pain that is present all the time and does not change in intensity.
* Intermittent pain: Pain that comes and goes and may be triggered by specific activities or stimuli.
* Sharp pain: Pain that is sudden and stabbing.
* Dull pain: Pain that is ongoing and aching.
* Throbbing pain: Pain that is pulsing or beating, often with a rhythmic pattern.

The causes of facial pain can vary depending on the location and severity of the pain. Some common causes include:

* Muscle tension or spasm
* Nerve irritation or compression
* Inflammation or infection
* Injury or trauma to the face
* Neurological disorders (e.g., trigeminal neuralgia, Bell's palsy)
* Dental problems (e.g., toothache, abscess)

The diagnosis of facial pain is based on a combination of medical history, physical examination, and diagnostic tests such as X-rays, CT scans, or MRI scans. Treatment for facial pain depends on the underlying cause and may include medications (e.g., pain relievers, antibiotics), lifestyle changes (e.g., avoiding triggers), or surgical intervention (e.g., to remove a tumor).

Synovial cysts are usually benign, meaning they are not cancerous, but they can cause significant discomfort and disrupt daily activities. Treatment options for synovial cysts include draining the fluid from the cyst, physiotherapy to improve range of motion and strength, or surgery to remove the cyst if it is large and causing persistent symptoms.

The formation of a synovial cyst is often caused by trauma to the joint or tendon, such as a fall or repetitive strain injury. It can also be caused by conditions such as rheumatoid arthritis or osteoarthritis, which can lead to inflammation and fluid buildup in the joints. In some cases, synovial cysts may be inherited or may occur spontaneously without any known cause.

Synovial cysts are usually diagnosed through a combination of physical examination, imaging tests such as X-rays or ultrasound, and arthroscopy, which involves inserting a small camera into the joint to view the inside of the joint and detect any abnormalities.

It's important to seek medical attention if you experience persistent pain or swelling in a joint, as these symptoms could be indicative of a synovial cyst or another underlying condition that requires treatment. With proper diagnosis and treatment, it is possible to effectively manage the symptoms of a synovial cyst and improve joint function and mobility.

The symptoms of tenosynovitis can vary depending on the location of the affected tendon, but common symptoms include:

* Pain and tenderness in the affected area
* Swelling and redness in the affected area
* Stiffness and limited range of motion in the affected joint
* Difficulty moving the affected limb or joint
* Clicking or snapping sensation in the affected joint

Tenosynovitis can be caused by a variety of factors, including:

* Overuse or repetitive strain on the tendon
* Injury or trauma to the affected area
* Age-related wear and tear on the tendons
* Certain medical conditions, such as gout or rheumatoid arthritis

Treatment for tenosynovitis usually involves rest, physical therapy, and anti-inflammatory medications. In severe cases, surgery may be necessary to repair the damaged tendon. It is important to seek medical attention if symptoms persist or worsen over time, as untreated tenosynovitis can lead to chronic pain and limited mobility.

Spondylitis, ankylosing can affect any part of the spine, but it most commonly affects the lower back (lumbar spine) and the neck (cervical spine). The condition can also affect other joints, such as the hips, shoulders, and feet.

The exact cause of spondylitis, ankylosing is not known, but it is believed to be an autoimmune disorder, meaning that the body's immune system mistakenly attacks healthy tissue in the joints. Genetics may also play a role in the development of the condition.

Symptoms of spondylitis, ankylosing can include:

* Back pain and stiffness
* Pain and swelling in the joints
* Limited mobility and flexibility
* Redness and warmth in the affected area
* Fatigue

If you suspect that you or someone you know may have spondylitis, ankylosing, it is important to seek medical attention for proper diagnosis and treatment. A healthcare professional can perform a physical examination and order imaging tests, such as X-rays or MRIs, to confirm the diagnosis and rule out other conditions.

Treatment for spondylitis, ankylosing typically involves a combination of medications and physical therapy. Medications may include nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and disease-modifying anti-rheumatic drugs (DMARDs). Physical therapy can help improve mobility and flexibility, as well as strengthen the muscles supporting the affected joints.

In severe cases of spondylitis, ankylosing, surgery may be necessary to repair or replace damaged joints. In some cases, the condition may progress to the point where the joints become fused and immobile, a condition known as ankylosis.

While there is no cure for spondylitis, ankylosing, early diagnosis and appropriate treatment can help manage symptoms and slow the progression of the disease. With proper care and support, individuals with spondylitis, ankylosing can lead active and fulfilling lives.

The hip joint is a ball-and-socket joint that connects the thigh bone (femur) to the pelvis. In a normal hip joint, the ball (the head of the femur) fits snugly into the socket (the acetabulum). However, in dogs with hip dysplasia, the ball and socket may not fit together properly, causing the joint to become loose or unstable. This can lead to inflammation, pain, and degenerative changes in the joint over time.

There are two main types of hip dysplasia in dogs: developmental hip dysplasia and degenerative hip dysplasia. Developmental hip dysplasia occurs when the hip joint does not form properly during fetal development, while degenerative hip dysplasia is caused by wear and tear on the joint over time.

The symptoms of hip dysplasia in dogs can vary depending on the severity of the condition, but may include:

* Lameness or difficulty walking
* Pain or discomfort
* Stiffness or limited mobility
* Difficulty rising or climbing stairs
* Decreased activity level or reluctance to exercise
* Grinding or clicking sounds when the dog moves its hip joint

Hip dysplasia is typically diagnosed through a combination of physical examination, radiographs (x-rays), and arthroscopy. Treatment options for the condition may include:

* Medication to manage pain and inflammation
* Weight management to reduce the strain on the joint
* Surgery to repair or replace the damaged joint
* Physical therapy to improve mobility and strength

Preventative measures such as feeding a balanced diet, providing plenty of exercise and weight management can help to reduce the risk of developing hip dysplasia in dogs. However, if the condition does occur, early diagnosis and treatment can help to manage the symptoms and improve the dog's quality of life.

Some common types of neurogenic arthropathy include:

1. Charcot joint: A condition characterized by progressive destruction of the joint and deformity due to nerve damage, often seen in people with diabetes or peripheral neuropathy.
2. Complex regional pain syndrome (CRPS): A chronic pain condition that typically affects one limb after an injury or trauma, causing discoloration, swelling, and stiffness in the affected area.
3. Reflex sympathetic dystrophy (RSD): A chronic pain condition that develops after an injury or trauma, characterized by swelling, stiffness, and pain in the affected limb.
4. Post-polio syndrome: A condition that affects people who had polio as children, causing muscle weakness, joint pain, and limited mobility.

The symptoms of neurogenic arthropathy can vary depending on the underlying cause and the severity of the nerve damage. Common symptoms include:

1. Pain: Joint pain is a primary symptom of neurogenic arthropathy, which can range from mild to severe and may be exacerbated by movement or activity.
2. Stiffness: The affected joints may become stiff and lose their normal range of motion, making it difficult to perform daily activities.
3. Swelling: Joint swelling is common in neurogenic arthropathy, especially in the early stages of the condition.
4. Limited mobility: As the condition progresses, people with neurogenic arthropathy may experience limited mobility in the affected joints, making it difficult to perform daily activities.
5. Muscle weakness: Weakness in the muscles surrounding the affected joint can contribute to joint instability and pain.

Treatment for neurogenic arthropathy depends on the underlying cause and the severity of the condition. Common treatments include:

1. Medications: Pain relievers, such as nonsteroidal anti-inflammatory drugs (NSAIDs) or opioids, can help manage joint pain and inflammation. Muscle relaxants may also be prescribed to reduce muscle spasms and stiffness.
2. Physical therapy: A physical therapist can work with individuals to develop an exercise program that helps maintain joint mobility and strength.
3. Orthotics or assistive devices: In some cases, orthotics or assistive devices such as canes, walkers, or wheelchairs may be necessary to help improve mobility and support the affected joints.
4. Surgery: In severe cases of neurogenic arthropathy, surgery may be necessary to repair or replace damaged tissue or realign bones and joints.
5. Alternative therapies: Some people with neurogenic arthropathy may find relief from alternative therapies such as acupuncture or massage.

It's important to note that each individual's treatment plan will be unique and may involve a combination of these options. It's best to work closely with a healthcare provider to determine the most appropriate course of treatment for each person.

1. Rheumatoid arthritis (RA): An autoimmune disease that causes inflammation in the joints, leading to pain, stiffness, and swelling.
2. Osteoarthritis (OA): A degenerative condition that occurs when the cartilage in the joints wears down over time, causing pain and stiffness.
3. Psoriatic arthritis (PsA): An inflammatory disease that affects both the skin and joints, often occurring in people with psoriasis.
4. Ankylosing spondylitis (AS): A condition that causes inflammation in the spine and peripheral joints, leading to stiffness and pain.
5. Lupus: An autoimmune disease that can affect multiple systems in the body, including the joints, skin, and kidneys.
6. Juvenile idiopathic arthritis (JIA): A condition that affects children under the age of 16, causing inflammation in the joints and potentially leading to long-term complications.
7. Sjogren's syndrome: An autoimmune disorder that affects the glands that produce tears and saliva, causing dryness in the eyes and mouth.
8. Fibromyalgia: A condition characterized by widespread pain, fatigue, and sleep disturbances.
9. Gout: A type of inflammatory arthritis caused by excessive levels of uric acid in the blood, leading to sudden and severe attacks of joint pain.
10. Osteoporosis: A condition characterized by brittle bones and an increased risk of fractures, often occurring in older adults.

Rheumatic diseases can be challenging to diagnose and treat, as they often involve complex symptoms and a range of possible causes. However, with the help of rheumatology specialists and advanced diagnostic tools, it is possible to manage these conditions effectively and improve quality of life for patients.

There are several types of edema, including:

1. Pitting edema: This type of edema occurs when the fluid accumulates in the tissues and leaves a pit or depression when it is pressed. It is commonly seen in the skin of the lower legs and feet.
2. Non-pitting edema: This type of edema does not leave a pit or depression when pressed. It is often seen in the face, hands, and arms.
3. Cytedema: This type of edema is caused by an accumulation of fluid in the tissues of the limbs, particularly in the hands and feet.
4. Edema nervorum: This type of edema affects the nerves and can cause pain, numbness, and tingling in the affected area.
5. Lymphedema: This is a condition where the lymphatic system is unable to properly drain fluid from the body, leading to swelling in the arms or legs.

Edema can be diagnosed through physical examination, medical history, and diagnostic tests such as imaging studies and blood tests. Treatment options for edema depend on the underlying cause, but may include medications, lifestyle changes, and compression garments. In some cases, surgery or other interventions may be necessary to remove excess fluid or tissue.

There are many different types of back pain, including:

1. Lower back pain: This type of pain occurs in the lumbar spine and can be caused by strained muscles or ligaments, herniated discs, or other factors.
2. Upper back pain: This type of pain occurs in the thoracic spine and can be caused by muscle strain, poor posture, or other factors.
3. Middle back pain: This type of pain occurs in the thoracolumbar junction and can be caused by muscle strain, herniated discs, or other factors.
4. Lower left back pain: This type of pain occurs in the lumbar spine on the left side and can be caused by a variety of factors, including muscle strain, herniated discs, or other factors.
5. Lower right back pain: This type of pain occurs in the lumbar spine on the right side and can be caused by a variety of factors, including muscle strain, herniated discs, or other factors.

There are many different causes of back pain, including:

1. Muscle strain: This occurs when the muscles in the back are overstretched or torn.
2. Herniated discs: This occurs when the soft tissue between the vertebrae bulges out and puts pressure on the surrounding nerves.
3. Structural problems: This includes conditions such as scoliosis, kyphosis, and lordosis, which can cause back pain due to the abnormal curvature of the spine.
4. Inflammatory diseases: Conditions such as arthritis, inflammatory myopathies, and ankylosing spondylitis can cause back pain due to inflammation and joint damage.
5. Infections: Infections such as shingles, osteomyelitis, and abscesses can cause back pain by irritating the nerves or causing inflammation in the spine.
6. Trauma: Traumatic injuries such as fractures, dislocations, and compression fractures can cause back pain due to damage to the vertebrae, muscles, and other tissues.
7. Poor posture: Prolonged sitting or standing in a position that puts strain on the back can lead to back pain over time.
8. Obesity: Excess weight can put additional strain on the back, leading to back pain.
9. Smoking: Smoking can reduce blood flow to the discs and other tissues in the spine, leading to degeneration and back pain.
10. Sedentary lifestyle: A lack of physical activity can lead to weak muscles and a poor posture, which can contribute to back pain.

It is important to seek medical attention if you experience any of the following symptoms with your back pain:

1. Numbness or tingling in the legs or feet
2. Weakness in the legs or feet
3. Loss of bladder or bowel control
4. Fever and chills
5. Severe headache or stiff neck
6. Difficulty breathing or swallowing

These symptoms could indicate a more serious condition, such as a herniated disc or spinal infection, that requires prompt medical treatment.

Gout can be caused by several factors including genetics, diet, obesity, alcohol consumption, and certain medical conditions like high blood pressure and kidney disease. Symptoms of gout typically include sudden and severe pain, swelling, redness, and warmth in the affected joint, often accompanied by fever.

Gout is diagnosed based on physical examination, medical history, and laboratory tests such as blood tests to check uric acid levels. Treatment for gout usually involves medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and colchicine to reduce inflammation and pain. In severe cases, hospitalization may be necessary to manage the condition.

Lifestyle modifications such as maintaining a healthy diet, losing weight if overweight or obese, limiting alcohol consumption, and staying hydrated can also help manage gout. In some cases, medications to lower uric acid levels such as allopurinol may be prescribed to prevent future attacks of gout.

Gout is a chronic condition that requires ongoing management to prevent complications such as joint damage and kidney stones. With proper treatment and lifestyle modifications, most people with gout can lead active and productive lives.

The term "osteomyelitis" comes from the Greek words "osteon," meaning bone, and "myelitis," meaning inflammation of the spinal cord. The condition is caused by an infection that spreads to the bone from another part of the body, such as a skin wound or a urinary tract infection.

There are several different types of osteomyelitis, including:

1. Acute osteomyelitis: This type of infection occurs suddenly and can be caused by bacteria such as Staphylococcus aureus or Streptococcus pneumoniae.
2. Chronic osteomyelitis: This type of infection develops slowly over time and is often caused by bacteria such as Mycobacterium tuberculosis.
3. Pyogenic osteomyelitis: This type of infection is caused by bacteria that enter the body through a skin wound or other opening.
4. Tubercular osteomyelitis: This type of infection is caused by the bacteria Mycobacterium tuberculosis and is often associated with tuberculosis.

Symptoms of osteomyelitis can include fever, chills, fatigue, swelling, redness, and pain in the affected area. Treatment typically involves antibiotics to fight the infection, as well as supportive care to manage symptoms and prevent complications. In severe cases, surgery may be necessary to remove infected tissue or repair damaged bone.

Preventing osteomyelitis involves taking steps to avoid infections altogether, such as practicing good hygiene, getting vaccinated against certain diseases, and seeking medical attention promptly if an infection is suspected.

The term "hallux valgus" comes from Latin words that mean "big toe turned away." It is estimated that about 25% of adults in the United States have some degree of hallux valgus, with women being more likely to develop the condition than men.

Hallux valgus is caused by a combination of genetic and environmental factors, such as wearing poorly fitting shoes or having a family history of the condition. It can also be brought on by certain injuries or conditions, such as arthritis or gout.

Symptoms of hallux valgus include:

* Pain or discomfort in the big toe
* Redness and swelling around the joint
* Difficulty walking or wearing shoes
* Thickening of the skin at the base of the big toe
* Corns or calluses on the side of the foot

Treatment for hallux valgus depends on the severity of the condition and can range from conservative measures such as wearing proper footwear, using orthotics, and taking anti-inflammatory medications to surgical interventions such as bunionectomy. Early diagnosis and treatment can help alleviate symptoms and prevent complications.

The causes of LBP can be broadly classified into two categories:

1. Mechanical causes: These include strains, sprains, and injuries to the soft tissues (such as muscles, ligaments, and tendons) or bones in the lower back.
2. Non-mechanical causes: These include medical conditions such as herniated discs, degenerative disc disease, and spinal stenosis.

The symptoms of LBP can vary depending on the underlying cause and severity of the condition. Common symptoms include:

* Pain that may be localized to one side or both sides of the lower back
* Muscle spasms or stiffness
* Limited range of motion in the lower back
* Difficulty bending, lifting, or twisting
* Sciatica (pain that radiates down the legs)
* Weakness or numbness in the legs

The diagnosis of LBP is based on a combination of medical history, physical examination, and diagnostic tests such as X-rays, CT scans, or MRI.

Treatment for LBP depends on the underlying cause and severity of the condition, but may include:

* Medications such as pain relievers, muscle relaxants, or anti-inflammatory drugs
* Physical therapy to improve strength and flexibility in the lower back
* Chiropractic care to realign the spine and relieve pressure on the joints and muscles
* Injections of corticosteroids or hyaluronic acid to reduce inflammation and relieve pain
* Surgery may be considered for severe or chronic cases that do not respond to other treatments.

Prevention strategies for LBP include:

* Maintaining a healthy weight to reduce strain on the lower back
* Engaging in regular exercise to improve muscle strength and flexibility
* Using proper lifting techniques to avoid straining the lower back
* Taking regular breaks to stretch and move around if you have a job that involves sitting or standing for long periods
* Managing stress through relaxation techniques such as meditation or deep breathing.

The prevalence of OAS increases with age, affecting approximately 60% of people over the age of 65. The condition can be caused by a variety of factors, including genetics, obesity, joint injuries, and degenerative conditions such as scoliosis or spondylolisthesis.

The symptoms of OAS can vary depending on the severity of the condition and the specific location of the affected joints. Common symptoms include:

Back pain: Pain in the back, which can radiate to the buttocks, thighs, or arms
Stiffness: Limited mobility and rigidity in the spine
Limited range of motion: Decreased flexibility and ability to move the spine
Muscle spasms: Involuntary contractions of the muscles in the back
Decreased height: Compression fractures or loss of disc height can cause the spine to curve or shrink, leading to a decreased height.

The diagnosis of OAS is typically made through a combination of physical examination, medical history, and imaging tests such as X-rays or MRIs. Treatment for OAS typically focuses on managing symptoms and slowing the progression of the condition. Conservative treatments may include:

Medications: Pain relievers, anti-inflammatory drugs, and muscle relaxants
Physical therapy: Exercise and stretching to improve flexibility and strength
Lifestyle modifications: Maintaining a healthy weight, bracing, and good posture
Injections: Corticosteroid injections or platelet-rich plasma (PRP) therapy
Surgery: In severe cases, surgical intervention may be necessary to relieve pressure on the spine, stabilize the joints, or fuse vertebrae together.

It is essential to seek medical attention if you experience any symptoms of OAS, as early diagnosis and treatment can help manage symptoms and slow the progression of the condition.

There are different types of osteitis, including:

1. Osteitis fibrosa: A benign condition characterized by the formation of fibrous tissue in the bone, which can cause pain and stiffness.
2. Osteitis multiformis: A chronic condition that causes multiple areas of bone inflammation, often seen in patients with rheumatoid arthritis or ankylosing spondylitis.
3. Osteitis pseudogout: A condition characterized by the deposition of crystals in the bone, which can cause episodes of sudden and severe joint pain.
4. Osteitis suppurativa: A chronic condition characterized by recurring abscesses or pockets of pus in the bone, often seen in patients with a history of skin infections.

Symptoms of osteitis can include pain, swelling, redness and warmth over the affected area. Treatment options may vary depending on the underlying cause, but may include antibiotics for infection, anti-inflammatory medications, or surgical intervention to drain abscesses or remove infected tissue.

The symptoms of spondylarthritis can vary, but may include:

* Back pain that improves with exercise
* Stiffness in the neck or lower back
* Painful joints in the hips or shoulders
* Reduced range of motion in the affected joints
* Fatigue
* Loss of appetite
* Fever
* Swollen lymph nodes

The exact cause of spondylarthritis is unknown, but it is thought to be an autoimmune disorder. This means that the immune system mistakenly attacks healthy tissue in the body, leading to inflammation and joint damage.

There is no cure for spondylarthritis, but medications and lifestyle changes can help manage the symptoms. Treatment options may include:

* Nonsteroidal anti-inflammatory drugs (NSAIDs) to reduce pain and inflammation
* Corticosteroids to reduce inflammation
* Disease-modifying anti-rheumatic drugs (DMARDs) to slow the progression of the disease
* Biologic agents to target specific proteins involved in the immune response
* Physical therapy to improve range of motion and strength
* Rest and exercise to manage fatigue

Early diagnosis and treatment can help manage the symptoms of spondylarthritis and prevent long-term complications such as joint damage or spinal fusion.

Examples:

1. A ruptured Achilles tendon occurs when the tendon that connects the calf muscle to the heel bone is stretched too far and tears.
2. A ruptured appendix occurs when the appendix suddenly bursts, leading to infection and inflammation.
3. A ruptured aneurysm occurs when a weakened blood vessel bulges and bursts, leading to bleeding in the brain.
4. A ruptured eardrum occurs when there is sudden pressure on the eardrum, such as from an explosion or a blow to the head, which causes it to tear.
5. A ruptured ovarian cyst occurs when a fluid-filled sac on the ovary bursts, leading to pain and bleeding.

Symptoms of rupture can include sudden and severe pain, swelling, bruising, and bleeding. Treatment for rupture depends on the location and severity of the injury and may include surgery, medication, or other interventions.

Types of Wrist Injuries:

1. Sprains and Strains: These are common wrist injuries that occur when the ligaments or muscles are stretched or torn due to sudden movements or overuse.
2. Fractures: A fracture is a break in one or more of the bones in the wrist, which can be caused by a fall onto an outstretched hand or by a direct blow to the wrist.
3. Tendinitis: This is inflammation of the tendons, which connect muscles to bones. Wrist tendinitis can occur due to repetitive movements such as typing or gripping.
4. Carpal tunnel syndrome: This is a condition where the median nerve, which runs down the arm and into the hand through a narrow passageway in the wrist, becomes compressed or pinched. It can cause pain, numbness, and tingling in the hand and wrist.
5. Wrist fracture-dislocations: This is a type of injury where a bone in the wrist is broken and displaced from its normal position.
6. Ganglion cysts: These are non-cancerous lumps that can develop on the top of the wrist, usually due to repetitive movement or inflammation.
7. De Quervain's tenosynovitis: This is a condition that affects the tendons on the thumb side of the wrist, causing pain and stiffness in the wrist and thumb.

Symptoms of Wrist Injuries:

1. Pain
2. Swelling
3. Bruising
4. Limited mobility or stiffness
5. Difficulty gripping or grasping objects
6. Numbness or tingling in the hand or fingers
7. Weakness in the wrist or hand

Treatment of Wrist Injuries:

The treatment for wrist injuries depends on the severity of the injury and can range from conservative methods such as rest, ice, compression, and elevation (RICE) to surgical intervention. Some common treatments include:

1. Immobilization: A cast or splint may be used to immobilize the wrist and allow it to heal.
2. Physical therapy: Gentle exercises and stretches can help improve mobility and strength in the wrist.
3. Medications: Pain relievers, anti-inflammatory drugs, or steroid injections may be prescribed to manage pain and inflammation.
4. Surgery: In some cases, surgery may be necessary to repair damaged tissue or realign bones.
5. Rest: Avoid activities that aggravate the injury and give your wrist time to heal.
6. Ice: Apply ice to the affected area to reduce pain and inflammation.
7. Compression: Use a compression bandage to help reduce swelling.
8. Elevation: Keep your hand elevated above the level of your heart to reduce swelling.

It's important to seek medical attention if you experience any of the following symptoms:

* Severe pain that doesn't improve with medication
* Swelling or bruising that gets worse over time
* Difficulty moving your wrist or fingers
* Deformity or abnormal alignment of the wrist
* Numbness or tingling in your hand or fingers
* Weakness or difficulty gripping objects

If you suspect that you have a wrist injury, it's important to seek medical attention as soon as possible. A healthcare professional can evaluate your symptoms and provide an accurate diagnosis and treatment plan.

There are two main types of shoulder dislocations:

1. Shoulder dislocation: This occurs when the ball at the top of the humerus is forced out of its socket in the scapula.
2. Multidirectional instability (MDI): This occurs when the connections between the humerus, scapula, and collarbone (clavicle) are loose or unstable, causing the shoulder to dislocate in multiple directions.

Symptoms of a shoulder dislocation may include:

* Severe pain in your shoulder
* Swelling and bruising around your shoulder
* Difficulty moving your arm or putting weight on it
* A visible deformity in your shoulder

If you suspect that you have a shoulder dislocation, it's important to seek medical attention right away. Your doctor may perform an X-ray or other imaging tests to confirm the diagnosis and determine the severity of the dislocation. Treatment options for a shoulder dislocation may include:

* Reduction: This is a procedure where your doctor manipulates the bones back into their proper position.
* Immobilization: Your arm may be immobilized in a sling or brace to allow the joint to heal.
* Physical therapy: After the initial injury has healed, physical therapy can help improve range of motion and strength in your shoulder.

In some cases, surgery may be necessary to repair any damage to the surrounding tissues or to realign the bones. It's important to follow your doctor's recommendations for treatment and rehabilitation to ensure proper healing and prevent future complications.

A sprain is a stretch or tear of a ligament, which is a fibrous connective tissue that connects bones to other bones and provides stability to joints. Sprains often occur when the joint is subjected to excessive stress or movement, such as during a fall or sudden twisting motion. The most common sprains are those that affect the wrist, knee, and ankle joints.

A strain, on the other hand, is a stretch or tear of a muscle or a tendon, which is a fibrous cord that connects muscles to bones. Strains can occur due to overuse, sudden movement, or injury. The most common strains are those that affect the hamstring, calf, and back muscles.

The main difference between sprains and strains is the location of the injury. Sprains affect the ligaments, while strains affect the muscles or tendons. Additionally, sprains often cause joint instability and swelling, while strains may cause pain, bruising, and limited mobility.

Treatment for sprains and strains is similar and may include rest, ice, compression, and elevation (RICE) to reduce inflammation and relieve pain. Physical therapy exercises may also be recommended to improve strength and range of motion. In severe cases, surgery may be required to repair the damaged tissue.

Prevention is key in avoiding sprains and strains. This can be achieved by maintaining proper posture, warming up before physical activity, wearing appropriate protective gear during sports, and gradually increasing exercise intensity and duration. Proper training and technique can also help reduce the risk of injury.

Overall, while sprains and strains share some similarities, they are distinct injuries that require different approaches to treatment and prevention. Understanding the differences between these two conditions is essential for proper diagnosis, treatment, and recovery.

There are several key features of inflammation:

1. Increased blood flow: Blood vessels in the affected area dilate, allowing more blood to flow into the tissue and bringing with it immune cells, nutrients, and other signaling molecules.
2. Leukocyte migration: White blood cells, such as neutrophils and monocytes, migrate towards the site of inflammation in response to chemical signals.
3. Release of mediators: Inflammatory mediators, such as cytokines and chemokines, are released by immune cells and other cells in the affected tissue. These molecules help to coordinate the immune response and attract more immune cells to the site of inflammation.
4. Activation of immune cells: Immune cells, such as macrophages and T cells, become activated and start to phagocytose (engulf) pathogens or damaged tissue.
5. Increased heat production: Inflammation can cause an increase in metabolic activity in the affected tissue, leading to increased heat production.
6. Redness and swelling: Increased blood flow and leakiness of blood vessels can cause redness and swelling in the affected area.
7. Pain: Inflammation can cause pain through the activation of nociceptors (pain-sensing neurons) and the release of pro-inflammatory mediators.

Inflammation can be acute or chronic. Acute inflammation is a short-term response to injury or infection, which helps to resolve the issue quickly. Chronic inflammation is a long-term response that can cause ongoing damage and diseases such as arthritis, asthma, and cancer.

There are several types of inflammation, including:

1. Acute inflammation: A short-term response to injury or infection.
2. Chronic inflammation: A long-term response that can cause ongoing damage and diseases.
3. Autoimmune inflammation: An inappropriate immune response against the body's own tissues.
4. Allergic inflammation: An immune response to a harmless substance, such as pollen or dust mites.
5. Parasitic inflammation: An immune response to parasites, such as worms or fungi.
6. Bacterial inflammation: An immune response to bacteria.
7. Viral inflammation: An immune response to viruses.
8. Fungal inflammation: An immune response to fungi.

There are several ways to reduce inflammation, including:

1. Medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and disease-modifying anti-rheumatic drugs (DMARDs).
2. Lifestyle changes, such as a healthy diet, regular exercise, stress management, and getting enough sleep.
3. Alternative therapies, such as acupuncture, herbal supplements, and mind-body practices.
4. Addressing underlying conditions, such as hormonal imbalances, gut health issues, and chronic infections.
5. Using anti-inflammatory compounds found in certain foods, such as omega-3 fatty acids, turmeric, and ginger.

It's important to note that chronic inflammation can lead to a range of health problems, including:

1. Arthritis
2. Diabetes
3. Heart disease
4. Cancer
5. Alzheimer's disease
6. Parkinson's disease
7. Autoimmune disorders, such as lupus and rheumatoid arthritis.

Therefore, it's important to manage inflammation effectively to prevent these complications and improve overall health and well-being.

Some common types of spinal diseases include:

1. Degenerative disc disease: This is a condition where the discs between the vertebrae in the spine wear down over time, leading to pain and stiffness in the back.
2. Herniated discs: This occurs when the gel-like center of a disc bulges out through a tear in the outer layer, putting pressure on nearby nerves and causing pain.
3. Spinal stenosis: This is a narrowing of the spinal canal, which can put pressure on the spinal cord and nerve roots, causing pain, numbness, and weakness in the legs.
4. Spondylolisthesis: This is a condition where a vertebra slips out of place, either forward or backward, and can cause pressure on nearby nerves and muscles.
5. Scoliosis: This is a curvature of the spine that can be caused by a variety of factors, including genetics, injury, or disease.
6. Spinal infections: These are infections that can affect any part of the spine, including the discs, vertebrae, and soft tissues.
7. Spinal tumors: These are abnormal growths that can occur in the spine, either primary ( originating in the spine) or metastatic (originating elsewhere in the body).
8. Osteoporotic fractures: These are fractures that occur in the spine as a result of weakened bones due to osteoporosis.
9. Spinal cysts: These are fluid-filled sacs that can form in the spine, either as a result of injury or as a congenital condition.
10. Spinal degeneration: This is a general term for any type of wear and tear on the spine, such as arthritis or disc degeneration.

If you are experiencing any of these conditions, it is important to seek medical attention to receive an accurate diagnosis and appropriate treatment.

Some common horse diseases include:

1. Equine Influenza (EI): A highly contagious respiratory disease caused by the equine influenza virus. It can cause fever, coughing, and nasal discharge.
2. Strangles: A bacterial infection of the lymph nodes, which can cause swelling of the neck and difficulty breathing.
3. West Nile Virus (WNV): A viral infection that can cause fever, weakness, and loss of coordination. It is transmitted by mosquitoes and can be fatal in some cases.
4. Tetanus: A bacterial infection caused by Clostridium tetani, which can cause muscle stiffness, spasms, and rigidity.
5. Rabies: A viral infection that affects the central nervous system and can be fatal if left untreated. It is transmitted through the saliva of infected animals, usually through a bite.
6. Cushing's Disease: A hormonal disorder caused by an overproduction of cortisol, which can cause weight gain, muscle wasting, and other health issues.
7. Laminitis: An inflammation of the laminae, the tissues that connect the hoof to the bone. It can be caused by obesity, overeating, or excessive exercise.
8. Navicular Syndrome: A condition that affects the navicular bone and surrounding tissue, causing pain and lameness in the foot.
9. Pneumonia: An inflammation of the lungs, which can be caused by bacteria, viruses, or fungi.
10. Colic: A general term for abdominal pain, which can be caused by a variety of factors, including gas, impaction, or twisting of the intestines.

These are just a few examples of the many potential health issues that can affect horses. Regular veterinary care and proper management can help prevent many of these conditions, and early diagnosis and treatment can improve the chances of a successful outcome.

The burden of chronic diseases is significant, with over 70% of deaths worldwide attributed to them, according to the World Health Organization (WHO). In addition to the physical and emotional toll they take on individuals and their families, chronic diseases also pose a significant economic burden, accounting for a large proportion of healthcare expenditure.

In this article, we will explore the definition and impact of chronic diseases, as well as strategies for managing and living with them. We will also discuss the importance of early detection and prevention, as well as the role of healthcare providers in addressing the needs of individuals with chronic diseases.

What is a Chronic Disease?

A chronic disease is a condition that lasts for an extended period of time, often affecting daily life and activities. Unlike acute diseases, which have a specific beginning and end, chronic diseases are long-term and persistent. Examples of chronic diseases include:

1. Diabetes
2. Heart disease
3. Arthritis
4. Asthma
5. Cancer
6. Chronic obstructive pulmonary disease (COPD)
7. Chronic kidney disease (CKD)
8. Hypertension
9. Osteoporosis
10. Stroke

Impact of Chronic Diseases

The burden of chronic diseases is significant, with over 70% of deaths worldwide attributed to them, according to the WHO. In addition to the physical and emotional toll they take on individuals and their families, chronic diseases also pose a significant economic burden, accounting for a large proportion of healthcare expenditure.

Chronic diseases can also have a significant impact on an individual's quality of life, limiting their ability to participate in activities they enjoy and affecting their relationships with family and friends. Moreover, the financial burden of chronic diseases can lead to poverty and reduce economic productivity, thus having a broader societal impact.

Addressing Chronic Diseases

Given the significant burden of chronic diseases, it is essential that we address them effectively. This requires a multi-faceted approach that includes:

1. Lifestyle modifications: Encouraging healthy behaviors such as regular physical activity, a balanced diet, and smoking cessation can help prevent and manage chronic diseases.
2. Early detection and diagnosis: Identifying risk factors and detecting diseases early can help prevent or delay their progression.
3. Medication management: Effective medication management is crucial for controlling symptoms and slowing disease progression.
4. Multi-disciplinary care: Collaboration between healthcare providers, patients, and families is essential for managing chronic diseases.
5. Health promotion and disease prevention: Educating individuals about the risks of chronic diseases and promoting healthy behaviors can help prevent their onset.
6. Addressing social determinants of health: Social determinants such as poverty, education, and employment can have a significant impact on health outcomes. Addressing these factors is essential for reducing health disparities and improving overall health.
7. Investing in healthcare infrastructure: Investing in healthcare infrastructure, technology, and research is necessary to improve disease detection, diagnosis, and treatment.
8. Encouraging policy change: Policy changes can help create supportive environments for healthy behaviors and reduce the burden of chronic diseases.
9. Increasing public awareness: Raising public awareness about the risks and consequences of chronic diseases can help individuals make informed decisions about their health.
10. Providing support for caregivers: Chronic diseases can have a significant impact on family members and caregivers, so providing them with support is essential for improving overall health outcomes.

Conclusion

Chronic diseases are a major public health burden that affect millions of people worldwide. Addressing these diseases requires a multi-faceted approach that includes lifestyle changes, addressing social determinants of health, investing in healthcare infrastructure, encouraging policy change, increasing public awareness, and providing support for caregivers. By taking a comprehensive approach to chronic disease prevention and management, we can improve the health and well-being of individuals and communities worldwide.

The exact cause of SPV is not known, but it is believed to be associated with genetic mutations or environmental triggers such as trauma or infection. The condition typically affects large joints such as the knees, hips, and elbows, and can also occur in the wrists and ankles.

Symptoms of SPV can include:

* Pain and stiffness in the affected joint, which can be exacerbated by activity or changes in weather
* Swelling and redness in the joint
* Limited range of motion in the joint
* Presence of pigmented villous projections within the synovial membrane, which can be visible on physical examination or imaging studies such as X-rays or MRI.

Diagnosis of SPV is based on a combination of clinical findings, imaging studies, and histopathology. Treatment options for SPV include:

* Pain management with medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids
* Physical therapy to improve joint mobility and strength
* Surgical removal of the pigmented villous projections, which can provide relief of symptoms in some cases.

Prognosis for SPV is generally good, with most patients experiencing resolution of symptoms and preservation of joint function over time. However, in rare cases, the condition can progress to more severe forms of arthritis or other complications.

1. Osteogenesis imperfecta (OI): This is a genetic disorder that affects the formation of collagen, which is essential for bone strength and density. People with OI have brittle bones that are prone to fractures, often from minimal trauma.
2. Achondroplasia: This is the most common form of short-limbed dwarfism, caused by a genetic mutation that affects the development of cartilage and bone. People with achondroplasia have short stature, short limbs, and characteristic facial features.
3. Cleidocranial dysostosis: This is a rare genetic disorder that affects the development of the skull and collarbones. People with cleidocranial dysostosis may have misshapen or absent collarbones, as well as other skeletal abnormalities.
4. Fibrous dysplasia: This is a benign bone tumor that can affect any bone in the body. It is caused by a genetic mutation that causes an overgrowth of fibrous tissue in the bone, leading to deformity and weakness.
5. Multiple epiphyseal dysplasia (MED): This is a group of disorders that affect the growth plates at the ends of long bones, leading to irregular bone growth and deformity. MED can be caused by genetic mutations or environmental factors.

These are just a few examples of developmental bone diseases. There are many other conditions that can affect the formation and development of bones during fetal life or childhood, each with its own unique set of symptoms and characteristics.

Open fracture: The bone breaks through the skin, exposing the bone to the outside environment.

Closed fracture: The bone breaks, but does not penetrate the skin.

Comminuted fracture: The bone is broken into many pieces.

Hairline fracture: A thin crack in the bone that does not fully break it.

Non-displaced fracture: The bone is broken, but remains in its normal position.

Displaced fracture: The bone is broken and out of its normal position.

Stress fracture: A small crack in the bone caused by repetitive stress or overuse.

The exact cause of spondylarthropathies is not known, but they are believed to be an autoimmune response, where the body's immune system mistakenly attacks healthy tissues in the joints and spine. Genetics also play a role in the development of these conditions, as they tend to run in families.

There is no cure for spondylarthropathies, but various treatments can help manage symptoms and slow down the progression of the disease. These may include medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) and disease-modifying anti-rheumatic drugs (DMARDs), physical therapy, and lifestyle modifications such as regular exercise and a healthy diet. In severe cases, surgery may be necessary to repair or replace damaged joints or spine.

Early diagnosis and treatment of spondylarthropathies are important to manage symptoms and prevent long-term complications such as permanent joint damage, loss of flexibility, and reduced lung function. If you experience persistent back pain or stiffness, it is essential to consult a healthcare professional for proper evaluation and diagnosis.

There are several types of flatfoot, including:

1. Congenital flatfoot: This type is present at birth and is caused by a defect in the development of the foot bones.
2. Acquired flatfoot: This type can develop over time due to injuries, arthritis, or other conditions that cause the arch to collapse.
3. Neuromuscular flatfoot: This type is caused by nerve or muscle disorders that affect the ability to control the foot's movements.
4. Traumatic flatfoot: This type is caused by an injury such as a fracture or tear of one or more of the tendons in the foot.
5. Pes planus: This type is characterized by a complete collapse of the arch, causing the entire sole of the foot to be in contact with the ground.

Flatfoot can cause symptoms such as pain in the heel and arch area, swelling, and difficulty walking or standing for long periods. Treatment options vary depending on the severity of the condition and may include conservative measures such as orthotics, physical therapy, and shoe modifications, or surgical interventions to correct the deformity.

1. Athlete's Foot (Tinea Pedis): A fungal infection that causes itching, burning, and cracking on the soles of the feet and between the toes.
2. Bunions: Bony growths on the side or base of the big toe, causing pain, redness, and swelling.
3. Corns and Calluses: Thickened areas of skin on the feet, often caused by poorly fitting shoes or repeated friction.
4. Plantar Fasciitis: Inflammation of the plantar fascia, a band of tissue that runs along the bottom of the foot, causing heel pain and stiffness.
5. Gout: A type of arthritis that causes sudden, severe pain in the feet and ankles, often accompanied by swelling and redness.
6. Hammertoes: Deformed toe joints, caused by poorly fitting shoes or muscle imbalance, leading to pain, corns, and calluses.
7. Ingrown toenails: Nails that grow into the skin, causing pain, redness, and swelling.
8. Osteoarthritis: Wear and tear on the joints of the feet, leading to pain, stiffness, and limited mobility.
9. Peripheral Neuropathy: Damage to the nerves in the feet, causing numbness, tingling, and pain.
10. Ulcers: Open sores on the skin of the feet, often caused by diabetes, poor circulation, or injury.

Foot diseases can be diagnosed through physical examination, imaging tests such as X-rays or CT scans, and laboratory tests to determine the cause of the condition. Treatment options vary depending on the specific disease, but may include medications, footwear modifications, orthotics, physical therapy, and in some cases, surgery.

Intra-articular fractures can be classified into several categories based on their location within the joint:

1. Intra-articular fractures of the shoulder: These include fractures of the humeral head, glenoid, and clavicle.
2. Intra-articular fractures of the elbow: These include fractures of the radial head and neck, coronoid process, and distal humerus.
3. Intra-articular fractures of the wrist: These include fractures of the scaphoid, lunate, and capitate bones.
4. Intra-articular fractures of the hip: These include fractures of the femoral head and acetabulum.
5. Intra-articular fractures of the knee: These include fractures of the tibial plateau, femoral condyle, and patella.
6. Intra-articular fractures of the ankle: These include fractures of the talus, calcaneus, and fibula.

Intra-articular fractures can be caused by a variety of factors, such as falls, sports injuries, and motor vehicle accidents. Treatment for these types of fractures often involves immobilization with a cast or brace, surgery to realign and stabilize the bones, and physical therapy to restore strength and range of motion. In some cases, arthroscopy may be used to help repair the joint and improve outcomes.

Overall, intra-articular fractures can be challenging to treat and require careful planning and execution to ensure proper healing and minimize complications. It is important for patients to seek medical attention if they experience symptoms such as pain, swelling, or difficulty moving the affected joint.

Symptoms:

* Pain in the lower back, hips, or legs
* Stiffness in the lower back
* Limited range of motion in the hip joint
* Redness and warmth over the affected joint
* Fatigue

Causes:

* Infection
* Arthritis
* Inflammatory diseases such as ankylosing spondylitis or psoriatic arthritis
* Injury to the sacroiliac joint

Diagnosis:

* Physical examination
* Imaging tests such as X-rays, CT scans, or MRI scans
* Blood tests to rule out other conditions

Treatment:

* Medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids to reduce inflammation and relieve pain
* Rest and physical therapy to improve range of motion and strength
* In severe cases, surgery may be necessary to repair or replace the damaged joint.

Gouty arthritis can cause sudden and severe pain, swelling, redness, and warmth in the affected joint, which can last for several days before subsiding. Attacks can be triggered by factors such as alcohol consumption, certain foods (like meat or seafood), stress, and certain medications.

Gouty arthritis is caused by a combination of genetic and lifestyle factors, including a diet high in purine-rich foods, obesity, alcoholism, and certain medical conditions such as hypertension or kidney disease. It can be difficult to diagnose gouty arthritis because the symptoms are similar to other forms of arthritis, but blood tests can help confirm the presence of uric acid crystals in the joint fluid.

Treatment for gouty arthritis typically involves medications to reduce inflammation and relieve pain, as well as lifestyle changes such as limiting alcohol intake and following a low-purine diet. In some cases, corticosteroids or other medications may be prescribed to help reduce inflammation and prevent future attacks.

Previous Post Definition of 'Arthritis' in the medical field.

The condition is caused by a variety of genetic mutations that can affect the development of the nervous system, muscles, or connective tissue. The symptoms of arthrogryposis can vary widely depending on the specific type and severity of the condition. They may include:

* Joint contractures: The joints become stiff and fixed in place, which can limit movement and cause deformities.
* Muscle weakness: The muscles may be weak or paralyzed, leading to difficulty moving the affected limbs.
* Delayed motor development: Children with arthrogryposis may experience delays in reaching developmental milestones such as sitting, standing, and walking.
* Limited range of motion: The joints may have a limited range of motion, making it difficult to move the affected limbs through their full range of motion.
* Muscle wasting: The muscles may waste away due to lack of use, leading to a weakened appearance.

There is no cure for arthrogryposis, but treatment options are available to help manage the symptoms and improve quality of life. These may include:

* Physical therapy: To maintain or improve muscle strength and range of motion.
* Occupational therapy: To assist with daily activities and fine motor skills.
* Surgery: To release contracted joints and improve mobility.
* Bracing and orthotics: To support weakened joints and improve posture.
* Medications: To manage pain and spasticity.

It is important to note that arthrogryposis is a complex condition, and the specific treatment plan will depend on the type and severity of the condition, as well as the individual needs of the patient. Early diagnosis and intervention are key to improving outcomes for individuals with arthrogryposis.

Anatomy82

Organisms5

Diseases64

Chemicals and Drugs19

Analytical, Diagnostic and Therapeutic Techniques and Equipment55

Psychiatry and Psychology4

Phenomena and Processes30

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena2

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Health Care18

Pyorrhoea as cause of pyrexia. (1/2057)

Sensory afferent properties of immobilised or inflamed rat knees during continuous passive movement. (2/2057)

Histology and tissue chemistry of tidemark separation in hamsters. (3/2057)

Transformations in embryonic motility in chick: kinematic correlates of type I and II motility at E9 and E12. (4/2057)

Role of proprioceptive signals from an insect femur-tibia joint in patterning motoneuronal activity of an adjacent leg joint. (5/2057)

Prevention of collagen-induced arthritis in mice by a polyphenolic fraction from green tea. (6/2057)

Extended field of view sonography in musculoskeletal imaging. (7/2057)

GDF5 coordinates bone and joint formation during digit development. (8/2057)

Joints

Knee Joint

Joint Diseases

Finger Joint

Ankle Joint

Hip Joint

Tarsal Joints

Wrist Joint

Joint Capsule

Sacroiliac Joint

Joint Instability

Temporomandibular Joint Disorders

Metatarsophalangeal Joint

Foot Joints

Shoulder Joint

Joint Prosthesis

Temporomandibular Joint Disc

Acromioclavicular Joint

Osteoarthritis

Arthritis, Rheumatoid

Sternoclavicular Joint

Cartilage, Articular

Synovial Fluid

Injections, Intra-Articular

Carpometacarpal Joints

Synovitis

Biomechanical Phenomena

Synovial Membrane

Range of Motion, Articular

Arthritis, Experimental

Arthrography

Arthritis, Infectious

Osteoarthritis, Knee

Arthralgia

Carpal Joints

Dislocations

Patellofemoral Joint

Weight-Bearing

Arthroplasty, Replacement

Movement

Ligaments, Articular

Stifle

Temporomandibular Joint Dysfunction Syndrome

Contracture

Ankylosis

Antirheumatic Agents

Joint Commission on Accreditation of Healthcare Organizations

Gait

Tibia

Prosthesis-Related Infections

Torque

Severity of Illness Index

Arthroplasty, Replacement, Knee

Hemarthrosis

Arthroscopy

Osteophyte

Hindlimb

Femur

Arthritis, Psoriatic

Cartilage

Arthroplasty

Cartilage Diseases

Chondrocytes

Pain

Lubrication

Hand

Collagen Type II

Joint Deformities, Acquired

Menisci, Tibial

Sternocostal Joints

Patella

Forelimb

Treatment Outcome

Knee Injuries

Anterior Cruciate Ligament

Proprioception

Ulna

Carpus, Animal

Tendons

Magnetic Resonance Imaging