Joints
Osteoarthritis
A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
Synovial Fluid
Arthritis, Rheumatoid
A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
Finger Joint
Arthritis, Psoriatic
Cartilage, Articular
Tarsal Joints
Ankle Joint
Hip Joint
Synovial Membrane
Synovitis
Wrist Joint
Arthritis, Infectious
Arthritis, Experimental
Foot Joints
Temporomandibular Joint Disorders
A variety of conditions affecting the anatomic and functional characteristics of the temporomandibular joint. Factors contributing to the complexity of temporomandibular diseases are its relation to dentition and mastication and the symptomatic effects in other areas which account for referred pain to the joint and the difficulties in applying traditional diagnostic procedures to temporomandibular joint pathology where tissue is rarely obtained and x-rays are often inadequate or nonspecific. Common diseases are developmental abnormalities, trauma, subluxation, luxation, arthritis, and neoplasia. (From Thoma's Oral Pathology, 6th ed, pp577-600)
Hip Dysplasia, Canine
Joint Capsule
Osteoarthritis, Knee
Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)
Cartilage
Spondylarthropathies
Heterogeneous group of arthritic diseases sharing clinical and radiologic features. They are associated with the HLA-B27 ANTIGEN and some with a triggering infection. Most involve the axial joints in the SPINE, particularly the SACROILIAC JOINT, but can also involve asymmetric peripheral joints. Subsets include ANKYLOSING SPONDYLITIS; REACTIVE ARTHRITIS; PSORIATIC ARTHRITIS; and others.
Rheumatoid Factor
Rheumatic Diseases
Spondylitis, Ankylosing
Temporomandibular Joint
Aggrecans
Tenosynovitis
Inflammation of the synovial lining of a tendon sheath. Causes include trauma, tendon stress, bacterial disease (gonorrhea, tuberculosis), rheumatic disease, and gout. Common sites are the hand, wrist, shoulder capsule, hip capsule, hamstring muscles, and Achilles tendon. The tendon sheaths become inflamed and painful, and accumulate fluid. Joint mobility is usually reduced.
Hemarthrosis
Arthritis, Reactive
An aseptic, inflammatory arthritis developing secondary to a primary extra-articular infection, most typically of the GASTROINTESTINAL TRACT or UROGENITAL SYSTEM. The initiating trigger pathogens are usually SHIGELLA; SALMONELLA; YERSINIA; CAMPYLOBACTER; or CHLAMYDIA TRACHOMATIS. Reactive arthritis is strongly associated with HLA-B27 ANTIGEN.
Severity of Illness Index
Osteophyte
Joint Instability
Collagen Type II
Metatarsophalangeal Joint
Toe Joint
Stifle
Nail Diseases
Shoulder Joint
Paleopathology
Arthritis, Juvenile
Arthritis of children, with onset before 16 years of age. The terms juvenile rheumatoid arthritis (JRA) and juvenile idiopathic arthritis (JIA) refer to classification systems for chronic arthritis in children. Only one subtype of juvenile arthritis (polyarticular-onset, rheumatoid factor-positive) clinically resembles adult rheumatoid arthritis and is considered its childhood equivalent.
Joint Prosthesis
Biomechanical Phenomena
Range of Motion, Articular
Temporomandibular Joint Disc
Acromioclavicular Joint
Hindlimb
Matrilin Proteins
PROTEOGLYCANS-associated proteins that are major components of EXTRACELLULAR MATRIX of various tissues including CARTILAGE; and INTERVERTEBRAL DISC structures. They bind COLLAGEN fibers and contain protein domains that enable oligomer formation and interaction with other extracellular matrix proteins such as CARTILAGE OLIGOMERIC MATRIX PROTEIN.
Extracellular Matrix Proteins
Macromolecular organic compounds that contain carbon, hydrogen, oxygen, nitrogen, and usually, sulfur. These macromolecules (proteins) form an intricate meshwork in which cells are embedded to construct tissues. Variations in the relative types of macromolecules and their organization determine the type of extracellular matrix, each adapted to the functional requirements of the tissue. The two main classes of macromolecules that form the extracellular matrix are: glycosaminoglycans, usually linked to proteins (proteoglycans), and fibrous proteins (e.g., COLLAGEN; ELASTIN; FIBRONECTINS; and LAMININ).
Rheumatology
Cartilage Oligomeric Matrix Protein
Matrix Metalloproteinase 13
Treatment Outcome
Tibia
Bone and Bones
Disease Progression
Sternoclavicular Joint
Biological Markers
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
Tumor Necrosis Factor-alpha
Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.
Interleukin-1
A soluble factor produced by MONOCYTES; MACROPHAGES, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. Interleukin-1 is a general term refers to either of the two distinct proteins, INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation.
Procollagen N-Endopeptidase
An extracellular endopeptidase which excises a block of peptides at the amino terminal, nonhelical region of the procollagen molecule with the formation of collagen. Absence or deficiency of the enzyme causes accumulation of procollagen which results in the inherited connective tissue disorder--dermatosparaxis. EC 3.4.24.14.
Psychotherapy, Multiple
Psoriasis
A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.
Immunoglobulin G
Vulvovaginitis
Pain
Enzyme-Linked Immunosorbent Assay
An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.
Chondroitin Sulfates
Derivatives of chondroitin which have a sulfate moiety esterified to the galactosamine moiety of chondroitin. Chondroitin sulfate A, or chondroitin 4-sulfate, and chondroitin sulfate C, or chondroitin 6-sulfate, have the sulfate esterified in the 4- and 6-positions, respectively. Chondroitin sulfate B (beta heparin; DERMATAN SULFATE) is a misnomer and this compound is not a true chondroitin sulfate.
Glycosaminoglycans
Plants
Multicellular, eukaryotic life forms of kingdom Plantae (sensu lato), comprising the VIRIDIPLANTAE; RHODOPHYTA; and GLAUCOPHYTA; all of which acquired chloroplasts by direct endosymbiosis of CYANOBACTERIA. They are characterized by a mainly photosynthetic mode of nutrition; essentially unlimited growth at localized regions of cell divisions (MERISTEMS); cellulose within cells providing rigidity; the absence of organs of locomotion; absence of nervous and sensory systems; and an alternation of haploid and diploid generations.
Follow-Up Studies
Arthrography
Cells, Cultured
Magnetic Resonance Imaging
Reproducibility of Results
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Carpal Joints
Methotrexate
Interleukin-1beta
Disability Evaluation
Drug Therapy, Combination
Inflammation
Prospective Studies
Anti-Inflammatory Agents, Non-Steroidal
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
Receptors, Tumor Necrosis Factor
Extracellular Matrix
Patellofemoral Joint
Antigen-Antibody Complex
Weight-Bearing
Immunoglobulin M
Cytokines
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
ADAM Proteins
Statistics, Nonparametric
A class of statistical methods applicable to a large set of probability distributions used to test for correlation, location, independence, etc. In most nonparametric statistical tests, the original scores or observations are replaced by another variable containing less information. An important class of nonparametric tests employs the ordinal properties of the data. Another class of tests uses information about whether an observation is above or below some fixed value such as the median, and a third class is based on the frequency of the occurrence of runs in the data. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1284; Corsini, Concise Encyclopedia of Psychology, 1987, p764-5)
Glycoproteins
Rabbits
Osteoclasts
Cattle
Movement
The act, process, or result of passing from one place or position to another. It differs from LOCOMOTION in that locomotion is restricted to the passing of the whole body from one place to another, while movement encompasses both locomotion but also a change of the position of the whole body or any of its parts. Movement may be used with reference to humans, vertebrate and invertebrate animals, and microorganisms. Differentiate also from MOTOR ACTIVITY, movement associated with behavior.
Dogs
C-Reactive Protein
RNA, Messenger
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Sensitivity and Specificity
Antibodies, Monoclonal, Humanized
Antibodies from non-human species whose protein sequences have been modified to make them nearly identical with human antibodies. If the constant region and part of the variable region are replaced, they are called humanized. If only the constant region is modified they are called chimeric. INN names for humanized antibodies end in -zumab.
Complement System Proteins
Serum glycoproteins participating in the host defense mechanism of COMPLEMENT ACTIVATION that creates the COMPLEMENT MEMBRANE ATTACK COMPLEX. Included are glycoproteins in the various pathways of complement activation (CLASSICAL COMPLEMENT PATHWAY; ALTERNATIVE COMPLEMENT PATHWAY; and LECTIN COMPLEMENT PATHWAY).
Ligaments, Articular
Case-Control Studies
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Temporomandibular Joint Dysfunction Syndrome
A symptom complex consisting of pain, muscle tenderness, clicking in the joint, and limitation or alteration of mandibular movement. The symptoms are subjective and manifested primarily in the masticatory muscles rather than the temporomandibular joint itself. Etiologic factors are uncertain but include occlusal dysharmony and psychophysiologic factors.
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Technology, Pharmaceutical
The application of scientific knowledge or technology to pharmacy and the pharmaceutical industry. It includes methods, techniques, and instrumentation in the manufacture, preparation, compounding, dispensing, packaging, and storing of drugs and other preparations used in diagnostic and determinative procedures, and in the treatment of patients.
Age Factors
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Contracture
Interleukin-6
Predictive Value of Tests
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Cohort Studies
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Sex Factors
Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.
Joint Commission on Accreditation of Healthcare Organizations
Mice, Knockout
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
Inflammation Mediators
Risk Factors
Aging
Phenotype
Reverse Transcriptase Polymerase Chain Reaction
Gene Expression
Pain Measurement
Dose-Response Relationship, Drug
Prosthesis-Related Infections
Blotting, Western
Torque
Immunohistochemistry
Quality of Life
Signal Transduction
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
Gene Expression Regulation
Questionnaires
Hand
Prognosis
Joint Deformities, Acquired
Sternocostal Joints
T-Lymphocytes
Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.
Anterior Cruciate Ligament
Proprioception
Sensory functions that transduce stimuli received by proprioceptive receptors in joints, tendons, muscles, and the INNER EAR into neural impulses to be transmitted to the CENTRAL NERVOUS SYSTEM. Proprioception provides sense of stationary positions and movements of one's body parts, and is important in maintaining KINESTHESIA and POSTURAL BALANCE.
Tendons
Arthrometry, Articular
Growth Differentiation Factor 5
Family study of inherited syndrome with multiple congenital deformities: symphalangism, carpal and tarsal fusion, brachydactyly, craniosynostosis, strabismus, hip osteochondritis. (1/1089)
A syndrome of brachydactyly (absence of some middle or distal phalanges), aplastic or hypoplastic nails, symphalangism (ankylois of proximal interphalangeal joints), synostosis of some carpal and tarsal bones, craniosynostosis, and dysplastic hip joints is reported in five members of an Italian family. It may represent a previously undescribed autosomal dominant trait. (+info)The clinical manifestations and pathomechanics of contracture of the extensor mechanism of the knee. (2/1089)
Experience with thirty-eight Asian children and adolescents who presented with either stiffness of the knee, genu recurvatum, habitual dislocation of the patella or congenital lateral dislocation of the patella showed that all those disorders were manifestations of contracture of the extensor mechanism, which fell into two groups according to the components involved. In Group I the main components affected were in the midline of the limb, namely rectus femoris and vastus intermedius; these patients presented with varying degrees of stiffness of the knee, or worse, with genu recurvatum. In Group II the main components involved were lateral to the midline of the limb, namely vastus lateralis and the ilio-tibial band; these patients presented with habitual dislocation of the patella, or worse, congenital lateral dislocation of the patella. In both groups untreated patients developed secondary adaptive changes such as subluxation of the tibia or marked genu valgum which made operative procedures more formidable and less effective. Release of the contracture should therefore be performed as early as possible. (+info)The locked patella. An unusual complication of haemophilia. (3/1089)
Mechanical derangements of the knee are an uncommon complication of chronic haemophiliac arthropathy. Two patients with locking of the patella were treated by manipulation. The mechanism of the injury was forced flexion of the knee joint beyond the limit of its restricted range. The injury is a serious one and may take six months to recover. (+info)Larsen syndrome in two generations of an Italian family. (4/1089)
This paper describes a familial case of Larsen syndrome. Typical anomalies were present in the propositus and 2 of his 6 daughters. In addition, all patients had progressive deafness and the 2 daughters had cleft palate. The certain exclusion of any consanguinity between the couple, suggests, in this instance, the dominant mode of transmission of the syndrome. (+info)Diagnostic classification of shoulder disorders: interobserver agreement and determinants of disagreement. (5/1089)
OBJECTIVES: To assess the interobserver agreement on the diagnostic classification of shoulder disorders, based on history taking and physical examination, and to identify the determinants of diagnostic disagreement. METHODS: Consecutive eligible patients with shoulder pain were recruited in various health care settings in the Netherlands. After history taking, two physiotherapists independently performed a physical examination and subsequently the shoulder complaints were classified into one of six diagnostic categories: capsular syndrome (for example, capsulitis, arthritis), acute bursitis, acromioclavicular syndrome, subacromial syndrome (for example, tendinitis, chronic bursitis), rest group (for example, unclear clinical picture, extrinsic causes) and mixed clinical picture. To quantify the interobserver agreement Cohen's kappa was calculated. Multivariate logistic regression analysis was applied to determine which clinical characteristics were determinants of diagnostic disagreement. RESULTS: The study population consisted of 201 patients with varying severity and duration of complaints. The kappa for the classification of shoulder disorders was 0.45 (95% confidence intervals (CI) 0.37, 0.54). Diagnostic disagreement was associated with bilateral involvement (odds ratio (OR) 1.9; 95% CI 1.0, 3.7), chronic complaints (OR 2.0; 95% CI 1.1, 3.7), and severe pain (OR 2.7; 95% CI 1.3, 5.3). CONCLUSIONS: Only moderate agreement was found on the classification of shoulder disorders, which implies that differentiation between the various categories of shoulder disorders is complicated. Especially patients with high pain severity, chronic complaints and bilateral involvement represent a diagnostic challenge for clinicians. As diagnostic classification is a guide for treatment decisions, unsatisfactory reproducibility might affect treatment outcome. To improve the reproducibility, more insight into the reproducibility of clinical findings and the value of additional diagnostic procedures is needed. (+info)Do postal questionnaires change GPs' workload and referral patterns? (6/1089)
OBJECTIVE: We aimed to determine changes in workload in general practice associated with the postal administration of a health needs questionnaire. METHOD: We carried out controlled before-and-after intervention study of the effects of delivering a postal questionnaire to assess needs for care for patients with arthropathies of the hip and knee, groin hernia and varicose veins, and to assess health service utilization, general health status and risk factors for cardiovascular disease. The setting was a seven-partner, fundholding, group practice in Avon. The subjects were patients registered with an NHS group practice situated in Backwell and Nailsea, Avon. The outcome measures were the frequency of consultation, home visits and night visits, reasons for consultation, referral to specialist agencies and patterns of prescribing. RESULTS: There was no significant difference between the study and control group in the year before and the year after the postal administration of the questionnaire with respect to changes in overall frequency of consultation, frequency of referral (including type of referral) and frequency of prescribing of non-steroidal anti-inflammatory drugs. In the study group there was a significant (P<0.05) reduction in the number of daytime home visits and prescriptions written for analgesics. Analysis of the records of those who had received a medical examination, in addition to a postal questionnaire, showed that there was no significant difference between the study and control group with respect to frequency of consultation, referral to outside agencies or items prescribed. CONCLUSION: Administration of a health needs questionnaire to patients registered with this general practice was not associated with an increase in consultation frequency or referral, or a change in prescribing patterns. No plausible explanation could be identified for the significant reduction in the number of home visits and prescriptions written for analgesics. It was concluded that these results were a statistical artefact. On the basis of the evidence from this study, GPs can be reassured that the administration of health needs questionnaires of the type used in this study will not result in any increase in workload or costs of care incurred by increased referrals to outside agencies or increased prescribing. (+info)Blood-induced joint damage: a human in vitro study. (7/1089)
OBJECTIVE: To investigate mechanisms underlying cartilage damage caused by brief exposure of cartilage to blood, such as that occurring during intraarticular bleeding. METHODS: Human articular cartilage was cultured for 4 days in the presence of blood (components; 7.5-50% volume/volume). The synthesis of cartilage matrix, as determined by proteoglycan synthesis (incorporation of 35SO4(2-)), was measured directly after exposure and after a recovery period of 20 days, during which the cartilage was cultured in the absence of blood or blood components. The production of the cytokines interleukin-1 (IL-1) and tumor necrosis factor a (TNFalpha), which have a destructive effect on cartilage, was determined by enzyme-linked immunosorbent assay, and the viability of chondrocytes was determined by measuring lactate dehydrogenase release and with electron microscopy. The involvement of oxygen metabolites was evaluated by using N-acetylcysteine. RESULTS: Brief exposure to blood resulted in dose-dependent inhibition of proteoglycan synthesis. The combination of mononuclear cells and red blood cells was responsible for this effect. The effect was irreversible, independent of IL-1 and TNFalpha production, and was accompanied by chondrocyte death. These effects were partially prevented by N-acetylcysteine. CONCLUSION: Brief exposure of cartilage to blood, as occurs after a single episode or a limited number of bleeding episodes, results in lasting cartilage damage in vitro, in which cytotoxic oxygen metabolites play a role. (+info)Blood-induced joint damage: a canine in vivo study. (8/1089)
OBJECTIVE: To investigate the direct and indirect (via synovial inflammation) effects of intraarticular bleeding on cartilage in vivo. METHODS: Right knees of 14 beagle dogs were injected with autologous blood on days 0 and 2. Cartilage matrix proteoglycan turnover, collagen damage, and synovial inflammation of these knees, including the cartilage-destructive properties of the synovial tissue, were determined and compared with those of the left control knees on day 4 (short-term effects; n = 7) and day 16 (long-term effects; n = 7). RESULTS: Injected knees had a diminished content of proteoglycans in the cartilage matrix, and release of proteoglycans was enhanced (days 4 and 16). The synthesis of proteoglycans was significantly inhibited on day 4 but was enhanced on day 16. On day 4 more collagen was denatured in the injected joint than in the control joint; this effect was no longer detectable on day 16. Synovial tissue showed signs of inflammation on day 4 and day 16 but had cartilage-destructive properties only on day 16. CONCLUSION: In vivo exposure of articular cartilage to blood for a relatively short time results in lasting changes in chondrocyte activity and in cartilage matrix integrity, changes that may predict lasting joint damage over time. Interestingly, the direct effect of blood on cartilage precedes the indirect effect via synovial inflammation. (+info)
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Rheumatoid disease of the spine
... an inflammatory autoimmune disease that attacks the ligaments, joints, and bones of the neck. Although the anterior subluxation ... Bulletin of the NYU Hospital for Joint Diseases. 69 (2): 136-148. ISSN 1936-9727. PMID 22035393. Wolfs, Jasper F. C.; ... Rheumatoid disease of the spine is a morbid consequence of untreated longstanding severe cervical spinal rheumatoid arthritis ( ... Progression of disease is measured via anterior atlantodental interval (AADI), and posterior atlantodental interval (PADI). ...
Adult-onset Still's disease
... is a form of Still's disease, a rare systemic autoinflammatory disease characterized by the classic triad of fevers, joint pain ... These included monocyclic systemic disease, polycyclic systemic disease, chronic articular monocyclic systemic disease, and ... The disease typically presents with joint pain, high fevers, a salmon-pink macular or maculopapular rash, enlargement of the ... A special form of joint disease met with in children. Doctoral dissertation, Cambridge, 1896. Kopeć-Mędrek, Magdalena; ...
New York University
"About Us". Hospital for Joint Diseases. NYU Langone Medical Center. Archived from the original on November 2, 2013. Retrieved ...
List of hospitals in Manhattan
The Hospital for Joint Diseases opened as the Jewish Hospital for Deformities and Joint Diseases at 1919 Madison Avenue in 1906 ... NYU Hospital for Joint Diseases, 301 East 17th Street, Manhattan. Incorporated as the Jewish Hospital for Deformities and Joint ... Hospital for Joint Diseases, Manhattan. See N.Y.U. Langone Medical Center, in the section on hospitals in Manhattan above. ... Consists of Tisch Hospital, the Rusk Institute of Rehabilitation Medicine, and the Hospital for Joint Diseases. Tisch Hospital ...
Sports injury
Öztürk, Selcen (2013). "What is the economic burden of sports injuries?". Joint Diseases and Related Surgery. 24 (2): 108-11. ... Runner's knee (Patellofemoral pain): knee joint pain affecting the patellofemoral joint. Pain is a direct consequence of the ... Preseason screenings consist of testing the mobility of joints (ankles, wrists, hips, etc.), testing the stability of joints ( ... The force the patellafemoral joint has to sustain can be as much as five times the body weight when the knee is fully flexed - ...
Intramedullary rod
Bulletin of the NYU Hospital for Joint Diseases. NYU Hospital for Joint Diseases. 64 (3/4): 94-97. PMID 17155917. Archived from ... If the bone breaks more medially, there is scope to position the nails further from the ankle joint which would prevent/reduce ... Joint Journal. 97-B (10): 1370-1376. doi:10.1302/0301-620X.97B10.35297. ISSN 2049-4394. Leung, Kwok-Sui; Kempf, Ivan; Alt, ...
List of hospitals in New York (state)
Bosco, Joseph (2007). "History of the NYU Hospital for Joint Diseases". Joint Diseases and Related Surgery. 18 (1): 44-46. " ... NY Langone Orthopedic Hospital was formerly the Hospital for Joint Diseases. Peconic Bay Medical Center was formerly Central ...
Racehorse injuries
"Joint disease". Equinenaturaltherapy.com. Retrieved 2011-06-24. "Carpal Bone Injuries". tree.com. Archived from the original on ... enzymes and other agents from the joint lining are released that destroy tissue inside the joint. As the condition worsens, so ... The joint capsule may also be completely ruptured and the articular portion of the bones exposed to view. An osselet is ... Osselets are a result of trauma, such as hard, heavy, or fast use, a slip or fall, or a direct blow to the joint. When the ...
Lyme disease
Dogs may also experience chronic joint disease if the disease is left untreated. However, the majority of cases of Lyme disease ... Lyme disease organizations at Curlie CDC - Lyme Disease Lyme Disease Tests - Lab Tests Online NIH - Lyme Disease NICE ... "Lyme disease rashes and look-alikes". Lyme Disease. Centers for Disease Control and Prevention. 21 December 2018. Archived from ... "Lyme Disease Data and surveillance". Lyme Disease. Centers for Disease Control and Prevention. 5 February 2019. Archived from ...
Systemic disease
Rheumatoid arthritis - an inflammatory disease which mainly attacks the joints. But can also affect a person's skin, eyes, ... Disease Disseminated disease Fred Siguier List of systemic diseases with ocular manifestations Localized disease Marfan ... Ulcerative colitis - an inflammatory bowel disease Crohn's disease - an inflammatory bowel disease Hypertension (high blood ... Almost any part of the eye can give important clues to the diagnosis of systemic diseases. Signs of a systemic disease may be ...
Global Alliance for Genomics and Health
"European Joint Programme on Rare Diseases". www.ejprarediseases.org. Retrieved 2022-03-24. Proffitt, Allison (October 17, 2017 ... and European Genome-phenome Archive at EMBL-EBI EUCANCan European Joint Programme on Rare Diseases Genomics England Human Cell ...
Spynie Hospital
The hospital has its origins in a facility designed by Reid and Wittet which opened as Elgin Joint County Infectious Diseases ... "Elgin Joint County Infectious Diseases Hospital". Dictionary of Scottish Architects. Retrieved 8 September 2009. "Spynie ...
John Edward Blair
Bulletin of the Hospital for Joint Diseases. Hospital for Joint Diseases Orthopaedic Institute. 1957. p. 77. "Obituary. John E ... In 1944, Blair and Joseph Buchman (1898-1965) at the Hospital for Joint Diseases were awarded a contract for the investigation ... In 1927 he became a bacteriologist and serologist at Manhattan's Hospital for Joint Diseases. He headed the hospital's ... Blair, John E.; Reeves, David L. (1928). "The Placental Transmission of Bacteriophage". The Journal of Infectious Diseases. 42 ...
Health promotion
The European Union is co-funding a Joint Action on Chronic Diseases and Healthy Ageing across the Life Cycle (JA-CHRODIS) with ... South China Morning Post 2007 Jul 7. "CHRODIS - Joint Action on Chronic Diseases". CHRODIS. Archived from the original on 2015- ... The disease burden has started to shift towards non-communicable diseases related to lifestyle and environmental factors. The ... A systematic analysis from the WHO/ILO Joint Estimates of the Work-related Burden of Disease and Injury". Environment ...
Munchkin cat
Ettinger, Stephen J.; Feldman, Edward C.; Bennett, D.; May, C. (1995). "Joint diseases of Dogs and Cats". Textbook of ... She X-rayed their joints and bones and found no evidence of crippling. So she began breeding Munchkins "Achondroplasia". ... Hubler, M.; Langley-Hobbs, S.J. (2009). "Hereditary and congenital musculoskeletal diseases". In Montavon, P.M.; Voss, K.; ... Breeding and Registration Rules: 2.7.3 Genetic Diseases. Fédération Internationale Feline Cat Fanciers' Association,CFA Breeds ...
Yttrium
Fischer, M.; Modder, G. (2002). "Radionuclide therapy of inflammatory joint diseases". Nuclear Medicine Communications. 23 (9 ... Exposure to yttrium compounds can cause lung disease in humans. The element is named after ytterbite, a mineral first ... Exposure to yttrium compounds in humans may cause lung disease. Workers exposed to airborne yttrium europium vanadate dust ... and yttrium-90 is also used to carry out radionuclide synovectomy in the treatment of inflamed joints, especially knees, in ...
Legg-Calvé-Perthes disease
Barker DJ, Dixon E, Taylor JF (1978). "Perthes' disease of the hip in three regions of England". J Bone Joint Surg Br. 60 (4): ... Although no one has identified the cause of Perthes disease, a reduction in blood flow to the joint is known.[citation needed] ... Kim HK (2012). "Pathophysiology and new strategies for the treatment of Legg-Calvé-Perthes disease". J Bone Joint Surg Am. 94 ( ... LCP disease is an avascular necrosis of the femoral head in small-breed dogs, usually those weighing up to 25 lbs. LCP disease ...
William Coulson
On Diseases of the Hip Joint, 1837; 2nd edit. 1841. On Diseases of the Bladder and Prostate Gland, 1838; 2nd edit. enlarged, ... They were published in the second edition of his Diseases of the Hip Joint. In 1827 he wrote notes to Henri Milne-Edwards's ... Lectures on Diseases of the Joints, 1854. Coulson also contributed the articles "Lithotomy" and "Lithotrity" to Samuel Cooper's ... His investigations on post-partum afflictions of the joints at the Lying-in Hospital contributed the knowledge of their nature ...
Rocker bottom foot
Robbins, H (October 1976). "Naviculectomy for congenital vertical talus". Bulletin of the Hospital for Joint Diseases. 37 (2): ... the orthopedic surgeon may resort to a minimally invasive surgery at the talo-navicular joint to achieve full correction. The ... The Journal of Bone and Joint Surgery. American Volume. 97 (16): 1354-1365. doi:10.2106/JBJS.N.01002. PMID 26290087. Mosca, ... The Journal of Bone and Joint Surgery. American Volume. 59 (6): 816-24. doi:10.2106/00004623-197759060-00016. PMID 908706. ...
Aaron Bodansky
"Hospital for Joint Diseases 1905-2005" (PDF). NYU Medical Center. Retrieved 9 July 2019. Ornish, Natalie. "Bodansky, Meyer ( ... Bodansky was hired into the laboratory division of the Hospital for Joint Diseases (now part of NYU Langone Medical Center). At ... the Hospital for Joint Diseases, Bodansky's work covered a variety of areas of biochemistry including thyroxin and insulin ...
Crescent sign
Bulletin of the Hospital for Joint Diseases. 24: 99-104. PMID 14048829. "Rheumatology Image Bank: Avascular Necrosis, Crescent ... It usually occurs later in the disease, in stage III of the four-stage Ficat classification system. It appears as a curved ... The crescent sign may be seen with other bone diseases, such as shear fractures. Pappas, J. N. (2000). "The musculoskeletal ...
Cabrini Medical Center
69th Annual Report - for the Year 1975 (PDF). Hospital for Joint Diseases and Medical Center. May 1976. p. 29. Lectures... ...
Nomura's jellyfish
One study sought to use the mucin of the Nomura's jellyfish to treat joint disease such as osteoarthritis. Like many invasive ... 2015). "Combined preparation for treating joint diseases". Patent US9095551. Retrieved 27 May 2016. Watanabe, Yusuke; Ochi, ...
Temporomandibular joint dysfunction
Rheumatoid arthritis, an autoimmune joint disease, can also affect the TMJs. Degenerative joint diseases may lead to defects in ... any disease of a joint (or specifically degenerative joint disease), and is also used as a synonym for osteoarthritis. In the ... Joint noises may require auscultation with a stethoscope to detect. Clicks of the joint may also be palpated, over the joint ... meaning there are in effect 2 joint capsules, creating an upper joint space and a lower joint space, with the articular disc in ...
VAMP regimen
Bulletin of the NYU Hospital for Joint Diseases. 65 (3): 168-173. ISSN 1936-9719. PMID 17922664. "Methotrexate: Mechanism of ... early-stage Hodgkin's disease: results of a prospective clinical trial". J. Clin. Oncol. 20 (14): 3081-7. doi:10.1200/jco. ... of a Prospective Clinical Trial With VAMP and Low-Dose Involved-Field Radiation for Children With Low-Risk Hodgkin's Disease. ...
Evidence-based medicine
Bulletin of the NYU Hospital for Joint Diseases. 67 (2): 198-205. PMID 19583554. Archived from the original on 1 June 2013. El ... Medicine has a long history of scientific inquiry about the prevention, diagnosis, and treatment of human disease. The concept ... and co-morbid diseases), evidence from RCTs may not be generalizable to those populations. Thus, EBM applies to groups of ... and whether antidepressant drugs are effective in people with Alzheimer's disease. Even when the evidence unequivocally shows ...
Wrist arthroscopy
Elkowitz, S. J.; Posner, M. A. (2006). "Wrist arthroscopy". Bulletin of the NYU Hospital for Joint Diseases. 64 (3-4): 156-165 ... Dorsal Distal Radioulnar joint portal (DDRUJ) Both the proximal and distal DRUJ can be used. It's the best way to get a clear ... In that way, the surgeon will be able to orient within the joint of the wrist. Once a clear view of the wrist is obtained, a ... This camera is attached to a fiberoptic light source and shows the image of the inside of the joint. Probes are used for ...
Gout
... indicates that pain and disease are to be apprehended in the region of joints or viscera... Joint troubles in the hands and ... Historically, it was referred to as "the king of diseases and the disease of kings" or "rich man's disease". The Ebers papyrus ... Other joints, such as the heels, knees, wrists, and fingers, may also be affected. Joint pain usually begins during the night ... Diagnosis of gout may be confirmed by the presence of crystals in the joint fluid or in a deposit outside the joint. Blood uric ...
Head and neck anatomy
Temporomandibular joint diseases and disorders, commonly called TMJ. Autoimmune diseases such as: Crohn's disease of the oral ... and contactable via skin to skin contact Other diseases include: Gingivitis gum disease, periodontal disease, oral forms of ... Diseases may be transmitted by contact of the head, mouth, or body fluids, such as Herpes Simplex Virus Type I (HSV-1), Herpes ... Crohn disease Brain-blood barrier, University of Washington Skin nerve receptors Cells Alive, Anatomy of a splinter Core ...
Rheumatoid arthritis
DAS28: Disease Activity Score of 28 joints (DAS28) is widely used as an indicator of RA disease activity and response to ... Joints included are (bilaterally): proximal interphalangeal joints (10 joints), metacarpophalangeal joints (10), wrists (2), ... hip joints, knees, and ankles as large joints: Involvement of 1 large joint gives 0 points Involvement of 2-10 large joints ... the interphalangeal joint of the thumb, second through fifth metatarsophalangeal joint and wrist as small joints, and shoulders ...
Wolfgang Fink
Fink has joint appointments in the Departments of Electrical & Computer Engineering, Biomedical Engineering, Systems & ... to develop an implantable microelectronic retinal device that restores useful vision to people blinded by retinal diseases ( ...
Chilean art
They held a joint exhibition at the Museum of Contemporary Art in 1980, entitled Promotion 80, under the curatorship of Milan ... causing many to die young from diseases such as malaria and tuberculosis. The 13 Generation emerged from the country's poorest ... They got their name from a joint exhibition held in 1913 in the offices of the Chilean newspaper El Mercurio. The group was ...
Thomas Lodge
Titus out of Joint: Reading the Fragmented Titus Andronicus. Newcastle upon Tyne: Cambridge Scholars Publishing. pp. 7-48. ISBN ... disease), People from West Ham, Alumni of Trinity College, Oxford, 16th-century English poets, English Renaissance dramatists, ...
Tobacco politics
During the first wave, a growing abundance of evidence linked tobacco to death and disease. Individual smokers filed lawsuits ... In 1954, tobacco companies published a joint press release called "A Frank Statement", which cast doubt on studies linking ... During the second wave, plaintiffs charged tobacco companies with failure to warn about the addiction and disease risk of ... However, the tobacco industry responded by challenging the science of smoking causing disease and claiming that smokers assumed ...
Benjamin Franklin
Detailing new American customs, he wrote that, "[t]hey resolved last spring to eat no more lamb; and not a joint of lamb has ... Infectious disease deaths in Pennsylvania, Les Neuf Sœurs, Masonic Grand Masters, Members of the American Philosophical Society ... Joint appointments were standard at the time, for political reasons.) He was responsible for the British colonies from ... "a little oil in the hollow joint of my cane". In a 1772 letter to Joseph Priestley, Franklin laid out the earliest known ...
Mid America Heart Institute
... of Missouri-Kansas City School of Medicine and has earned the certification as a Comprehensive Cardiac Center from the Joint ... angioplasty in a patient with an acute myocardial infarction in 1981 First balloon angioplasty for coronary artery disease in ...
El Paso, Texas
A joint study by Fort Bliss and El Paso-area city governments found that desalination was a viable method for increasing El ... One prominent form of segregation, in the form of immigration controls to prevent disease, allegedly were abused to create ... Operations headquartered in El Paso include the DEA Domestic Field Division 7, El Paso Intelligence Center, Joint Task Force ... Joint Task Force North, United States Border Patrol El Paso Sector, and U.S. Border Patrol Special Operations Group. El Paso is ...
Cauliflower ear
Joints, eyes, audiovestibular system, cardiovascular system, and respiratory tract can also be involved. The components of the ... Diseases of the ear and mastoid process, Ear, Skin conditions resulting from physical factors, Sports injuries, Martial arts ...
Robot research initiative
RRI portal Joint Robotics Lab Intravascular microrobot Pioneer research center Uni Lab Microrobotics Nanorobotics Biorobotics " ... Microrobot moving controlled through blood vessel for drug delivery and treatment of coronary artery disease such as CTO( ...
Polish plait
Pain (especially in joints), rheumatism, etc. were synonymous with it. If plica was present, it was blamed for whims and ... An example of the belief in the spread of plica as a contagious disease by foreign hosts was the Victorian-era British belief ... As people believed that the formation of plica was a sign of resolving of disease, plica, as a hairstyle, was also formed ... In German and Bohemian spells, there are as many as seventy diseases. Poles were afraid to upset the unclean spirit, and, to ...
Prostitution in Austria
A quarter of the arrested unregistered prostitutes had multiple infections with sexually transmitted diseases. On the other ... Crime Office implemented programs with China and Nigeria to combat cross-border trafficking and improve and expand joint ...
Haemophilia A
Joint damage is not a result of blood in the capsule but rather the healing process. When blood in the joint is broken down by ... enzymes in the body, the bone in that area is also degraded, this exerts a lot of pain upon the person affected by the disease ... Repeated bleeds into a joint capsule can cause permanent joint damage and disfigurement resulting in chronic arthritis and ... Joints Muscles Digestive tract Brain Muscle and joint haemorrhages - or haemarthrosis - are indicative of haemophilia, while ...
List of feminist comic books
Manga serialized in Melody magazine, about an alternate history medieval Japan in which an unknown disease kills most of the ... Comix Joint. Retrieved December 20, 2014. Burns, Kate (2003). "Cartoons and comic books," in George Haggerty, Bonnie Zimmerman ...
Pauline Cafferkey
The prognosis after recovery from Ebola virus disease can include joint pains, muscular pain, skin peeling, or hair loss. In a ... "Study of Ebola Virus Disease Survivors in Guinea: Table 1". Clinical Infectious Diseases. 61 (7): 1035-1042. doi:10.1093/cid/ ... Pauline Cafferkey is a Scottish nurse and aid worker who contracted Ebola virus disease in 2014 while working in Sierra Leone ... Goeijenbier M, van Kampen JJ, Reusken CB, Koopmans MP, van Gorp EC (November 2014). "Ebola virus disease: a review on ...
History of the Jews in Poland
The American Jewish Joint Distribution Committee and Jewish Agency for Israel estimate that there are between 25,000 and ... During the next year and a half, Jews from smaller cities and villages were brought into the Warsaw Ghetto, while diseases ( ... Hospitals and schools were opened in Poland by the American Jewish Joint Distribution Committee and ORT to provide service to ... OCLC 837032828 Yehuda Bauer, A History of the American Jewish Joint Distribution Committee 1929-1939. End note 20: 44-29, memo ...
Harold Hitz Burton
He was diagnosed with Parkinson's disease. The shaking in his left arm had become so severe by the start of 1958 that he ... He wrote the majority opinion in Joint Anti-Fascist Refugee Committee v. McGrath (1951) and Lorain Journal Co. v. United States ... Burton publicly announced that he was suffering from Parkinson's disease. He retired on the advice of physicians, who said the ... He died on October 28, 1964, in Washington, D.C., from complications arising from Parkinson's disease, kidney failure, and ...
Marion Rosen
Done in a group and set to music, these movements gently and systematically improve range of movement and joint lubrication. ... "The neurobiology of interoception in health and disease: Neuroscience of interoception". Annals of the New York Academy of ...
Bougainville campaign
8,500 Japanese were killed at the same time, while disease and malnutrition killed another 9,800 and some 23,500 troops and ... The Joint Chiefs of Staff had determined that Rabaul was to be encircled, with invasions of the Admiralty Islands and Kavieng ... Long's figures are quoted in the narrative, totalling 16,700 combat deaths and 26,400 deaths from disease and malnutrition. ... Footnotes Figure includes deaths from all causes: combat, disease, starvation, and accident. The Australians counted 21,000 to ...
Neomodernism
To him, it involves common goal and joint global effort - universalism - to address arising global challenges such as ... eradicating diseases, enhancing literacy rates and addressing climate changes. Technological advancement of the neomodern era ...
Catherine Jane Wood
In March 1867, the new Hospital, initially called "The House of Relief for Children with Chronic Diseases of the Joints", ... created to host children affected by joint diseases. ... "The Alexandra Hospital for Children with Hip Disease" in honour ...
Robert Byrne (chess player)
Deaths from Parkinson's disease, Indiana University faculty, Neurological disease deaths in New York (state), People from ... a point behind joint winners Bobby Fischer and Arthur Bisguier. Byrne did not play in his first U.S. Chess Championship until ... Byrne died in 2013 at his home in Ossining, New York, from Parkinson's disease. David Bronstein vs Robert Byrne, Helsinki ...
Woodrow Wilson
The health of Wilson's wife, Ellen, declined after he entered office, and doctors diagnosed her with Bright's disease in July ... Wilson introduced these proposals in April 1913 in a speech delivered to a joint session of Congress, becoming the first ... His mind remained relatively clear; but he was physically enfeebled, and the disease had wrecked his emotional constitution and ... Neurological disease deaths in Washington, D.C., New Jersey Democrats, Nobel Peace Prize laureates, People from Kalorama ( ...
Bart-Pumphrey syndrome
... proximal and distal interphalangeal joints. It was characterized in 1967. It can be associated with GJB2. Camisa disease List ...
Rehabilitation psychology
Patterson, David R.; Hanson, Stephanie L. (Winter 1995). "Joint Division 22 and ACRM guidelines for postdoctoral training in ... Parkinson's disease, multiple sclerosis, mild cognitive impairment, ADHD, and a variety of other medical conditions that affect ...
2015 in aviation
Central Intelligence Agency and Joint Special Operations Command are engaged in a joint lethal unmanned aerial vehicle campaign ... Fair for designing a system of fin-like devices that can be installed in the air inlets of a Boeing 737 to reduce disease ... A joint statement sign by the governments of France, Germany, Qatar, Saudi Arabia, Turkey, the United Kingdom, and the United ... The United States Marine Corps announces that the F-35B Lightning II, its version of the F-35 Lightning II Joint Strike Fighter ...
Commentarii de Bello Gallico
... elks without joints or ligatures, and uri who kill every man they come across. However, the distinguishing characteristic of ... and other Roman authors assert that the Druids would offer human sacrifices on numerous occasions for relief from disease and ...
Childbirth
In a joint statement, World Health Organization, the International Federation of Gynaecology and Obstetrics and the ... The U.S. Centers for Disease Control and Prevention (CDC) has led an initiative to improve woman's health previous to ... Martin RJ, Fanaroff AA, Walsh MC (2014). Fanaroff and Martin's Neonatal-Perinatal Medicine: Diseases of the Fetus and Infant. ... "Recent Declines in Induction of Labor by Gestational Age". Centers for Disease Control and Prevention. Retrieved 9 May 2018. ...
Equine anatomy
Tendons are classified as flexors (flex a joint) or extensors (extend a joint). However, some tendons will flex multiple joints ... Diseases and surgery of the globe and orbit". In Gilger, BC (ed.). Equine Ophthalmology (3rd ed.). John Wiley & Sons. p. 151. ... joint; homologous to the "ball" of the foot or the metacarpophalangeal joints of the fingers in humans Flank: where the hind ... and coffin joint, but extend the hock joint). In this case, the tendons (and associated muscles) are named for their most ...
Meta (academic company)
The technology for the platform was developed via a joint partnership between Meta and SRI International. Meta merged with the ... Users can subscribe to feeds for areas of research including biology, genes, diseases, genetic disorders, drugs, people, labs ...
Tianjin Medical University
The agreement formalizes a cooperative framework to develop joint programs that support the institutions' shared missions of ... The eight Local-level Key Disciplines are Endocrinology and Metabolic Disease, Oncology, Neurology, Medical Imaging, Urinary ... Surgery, Cardiovascular Diseases, Nuclear Medicine and General Surgery. Three Local-level Key Development Disciplines are ...
Ver por tema "Joint Diseases"
Joint Disease | Introduction to Hemophilia Care | NCBDDD | CDC
Reduces joint bleeds and risk of chronic joint disease. 2. Treat at first sign of hemorrhage. Treatment at the earliest sign of ... Prevention of Chronic Joint Disease. 1. Recommend primary prophylaxis. *Recommended for children to prevent recurrent joint ... As a result, most have target joints and many have significant joint disease. Hemophilia arthropathy can affect patients both ... Early treatment of each joint bleed reduces the risk of chronic joint disease, functional impairment, and disability. Factor ...
Ver por tema "Joint Diseases"
Bulleidia extructa Periprosthetic Hip Joint Infection, United States - Volume 19, Number 7-July 2013 - Emerging Infectious...
Bulleidia extructa Periprosthetic Hip Joint Infection, United States. Emerging Infectious Diseases. 2013;19(7):1170-1171. doi: ... Periprosthetic joint infections are a major complication after joint replacement. The number of procedures for total hip and ... Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People ... 5.1-cm vascular mass extending anteriorly from the joint space. Aspiration of the joint space yielded 1 mL of blood-stained ...
WHO EMRO | Joint efforts to reduce vector-borne diseases across Khartoum | Sudan-news | Sudan
Sudan , News , Joint efforts to reduce vector-borne diseases across Khartoum Section menu. You are here. *Sudan*WHO presence in ... It is our joint responsibility to combat such diseases, provide the right treatment, upgrade Sudans health system, and improve ... WHO adopts vector control as part of its strategy to reduce infection rates and the spread of vector-borne diseases in the ... To effectively reduce the sources of vectors and reduce potential impacts of vector borne diseases, the WHO is supporting the ...
WHO pledges to support African countries on joint coronavirus disease preparedness and response strategy | WHO | Regional...
WHO joined Health Ministers in an Emergency Meeting on the Coronavirus Disease Outbreak, which was convened on 22 February by ... As the threat of coronavirus disease looms over the continent, the World Health Organization (WHO) promised to support African ... WHO pledges to support African countries on joint coronavirus disease preparedness and response strategy 22 February 2020. ... WHO pledges to support African countries on joint coronavirus disease preparedness and response strategy ...
Alkem Labs launches off-the-shelf cell therapy StemOne for knee joint diseases | The Financial Express
Knee Osteoarthritis is one of the most common debilitating diseases experienced within an ageing population and constitutes an ... Alkem Labs launches off-the-shelf cell therapy StemOne for knee joint diseases. Knee Osteoarthritis is one of the most common ... alkem labs launches off the shelf cell therapy stemone for knee joint diseases ... a degenerative disease of the joint. The company claims that It is the first allogeneic cell therapy product to be approved for ...
Drugs: musculoskeletal and joint diseases | BMJ Evidence-Based Medicine
Spinal Manipulation May Help Reduce Spinal Degenerative Joint Disease and Disability
... http://www.chiro.org/ChiroZine/ABSTRACTS/ ... Could the hypomobile manipulable joint lesion cause degenerative joint disease? Kirkaldy-Willis believes that an episode of ... Joint fixation and degenerative joint disease. "The Subluxation Complex" seminar notes. Los Angeles College of Chiropractic ... It is clear from the above that hypomobile animal joints develop degenerative joint disease but Junghanns, Baker, and Kirkaldy- ...
Hyaluronic acid, an efficient biomacromolecule for treatment of inflammatory skin and joint diseases: A review of recent...
... have also been well-documented for treatment of various types of joint disease including knee osteoarthritic, joint ... Hyaluronic acid, an efficient biomacromolecule for treatment of inflammatory skin and joint diseases: A review of recent ... and critically appraise the recent developments and efficacy of HA for treatment of inflammatory skin and joint diseases. A ... Intra-articular injection of HA produces remarkable reduction in joint pain, synovial inflammation, and articular swelling. A ...
6M UA fund for diseases of joints - Flinn Foundation
Source: Eric Swedlund, Arizona Daily Star] - The University of Arizona has created a new endowed faculty position and research fund for the study of rheumatology, funded by a $6 million bequest from a longtime Tucson doctor.. Dr. Salvatore Albani was appointed Monday as the Charles A.L. and Suzanne M. Stephens Chair of Rheumatology. Albani, who begins next month, will also serve as the director of the Arizona Arthritis Center.. Dr. Charles Stephens and his wife Suzanne left their entire estate to fund rheumatology research at the College of Medicine. Dr. Stephens was a captain in the U.S. Army, working in rheumatology and treating concentration camp survivors at the end of World War II. After leaving the army as a major in 1946, he joined the Holbrook-Hill Medical Clinic in Tucson.. Stephens was also an early faculty member in the UAs medical school and worked with the Arthritis & Rheumatism Foundation and Southwest Clinic and Research Institute, early organizations that helped develop the ...
The Center For Bone And Joint Disease: Homosassa, FL
Learn about The Center For Bone And Joint Disease. See providers, locations, and more. Book your appointment today! ... About The Center For Bone And Joint Disease The Center For Bone And Joint Disease is a Practice with 1 Location. Currently The ... View all providers that belong to The Center For Bone And Joint Disease. ... treat chronic diseases, like diabetes and asthma, and provide advice on disease prevention. ...
China, U.S. to further collaborate in health, disease control: joint statement CCTV-International
... according to a joint statement issued after the talks between Chinese President Hu Jintao and visiting U.S. President Barack ... States agreed here Tuesday to further collaboration to jointly research in the health sector and in the control of diseases, ... China, U.S. to further collaborate in health, disease control: joint statement. 2009-11-17 14:19 BJT Special Report: US ... The joint research will include that on stem cells. Both sides will deepen cooperation on global public health issues, ...
Autophagy regulates TNFα-mediated joint destruction in experimental arthritis | Annals of the Rheumatic Diseases
These findings further highlight the key role of autophagy in TNFα-induced joint disease and suggest translational implications ... In summary, we provide evidence for a central role of autophagy in osteoclastogenesis and destructive joint disease. Autophagy ... 25-27 and may also contribute to the enhanced activation of autophagy in erosive joint disease. This may result in a highly ... A) Representative H&E staining images of the tarsal joints from Atg7fl/fl×LysM Cre− → hTNFα or Atg7fl/fl×LysM Cre+ → hTNFα tg ...
SEA/RC38/7 - Special Programme for Research and Training in Tropical Diseases - Joint Coordinating Board - Nomination of a...
Search of: Temporomandibular Joint Disorders AND Myofascial Pain Syndromes AND Temporomandibular Joint AND Temporomandibular...
NMRC | NRF-MOST Joint Grant Call (Infectious Diseases)
Facts and Figures Our Structure Our Board Members Annual Reports Newsletter HBMS Disease Taskforces Reports ... Up to 4 projects will be supported under the joint grant call. Each project can be funded at up to S$500,000 (inclusive of 20% ... Singapore applicants to the joint grant call are to adhere to NMRCs instructions, guidelines as well as terms and conditions. ... The National Medical Research Council of the Republic of Singapore ("NMRC") will be the Implementing Agency for the joint grant ...
Top 3 Therapeutic Enzymes: Relief for Bowel Problems, Joint Pain, Heart Disease - Vitality Magazine
Top 3 Therapeutic Enzymes: Relief for Bowel Problems, Joint Pain, Heart Disease. Dr. Zoltan P. Rona, MD, M.Sc. July 24, 2018 ... Top 3 Therapeutic Enzymes: Relief for Bowel Problems, Joint Pain, Heart Disease ... Proponents recommend lumbrokinase as a treatment for angina, diabetes, heart disease, ischemic stroke, and Lyme disease. There ... These include diarrhea, gas, bloating, constipation, inflammatory bowel disease (e.g. Crohns disease and ulcerative colitis), ...
proDGNE - EJP RD - European Joint Programme on Rare Diseases
EJP RD - European Joint Programme on Rare Diseases. - News and events. - News. - proDGNE. ... The ProDGNE consortium, funded as part of the EJP RDs Joint Transnational Call 2020 "Pre-Clinical Research to Develop ... Fostering innovation for rare diseases in Europe: Chiesi supports the RDR Challenges Call ... networking event networking support scheme NSS OMP regulation open call orphan drugs paediatric patient patients rare diseases ...
European Joint Programme on Rare Diseases (EJP RD) - „Transnationale Forschungsprojekte zur Beschleunigung der Diagnose und...
Im Rahmen des European Joint Programme on Rare Diseases (EJP RD) erhält das Projekt „EJPRD2019-33 PredACTINg ... European Joint Programme on Rare Diseases (EJP RD) - „Transnationale Forschungspro-jekte zur Beschleunigung der Diagnose und/ ... Im Rahmen des European Joint Programme on Rare Diseases (EJP RD) erhält das Projekt „EJPRD2019-33 PredACTINg" eine Förderung ... Insgesamt wurden im European Joint Programme on Rare Diseases (EJP RD 2019) 217 Anträge eingereicht, von denen 52 detailliert ...
DoD Joint Program Committee-2/Military Infectious Diseases Applied Research Award
Image: Degenerative joint disease, radiograph - MSD Veterinary Manual
Ethics and law and palliative medicine joint session | Archives of Disease in Childhood
Huntington's Disease pot Archives - The Joint Blog
Calcium pyrophosphate dihydrate crystal deposition disease and MRSA septic arthritis of the atlantoaxial joint in a patient...
Calcium pyrophosphate dihydrate crystal deposition disease and MRSA septic arthritis of the atlantoaxial joint in a patient ... Calcium pyrophosphate dihydrate crystal deposition disease and MRSA septic arthritis of the atlantoaxial joint in a patient ... CT and MRI of the neck showed calcification of the longus colli, fluid and capsular distention of C1-C2 joints, enhancement of ... Fluid was aspirated from C1 to C2 joint by interventional radiology and showed calcium pyrophosphate crystals and heavy MRSA ...
Degenerative joint disease in cats (Proceedings)
Musculoskeletal disease (e.g., degenerative joint disease, osteoarthritis) is less well recognized in cats than in dogs. ... Sometimes, degenerative joint disease may be a cause of the cat apparently slowing down with age. In these cases, treatment ... However, it is surprising how often degenerative joint disease is discovered as an incidental finding on feline radiographs. ... This avulsion may be seen as a small joint mouse on radiographs. Early recognition and joint stabilization can prevent severe ...
Keywords gross + bones + joints + vertebra + hodgkins disease | PEIR Digital Library
Independent and joint effects of the MAPT and SNCA genes in Parkinson disease. - Elbaz Alexis
Reference : Independent and joint effects of the MAPT and SNCA genes in Parkinson disease.. ... Independent and joint effects of the MAPT and SNCA genes in Parkinson disease. ... It shows, based on a variety of approaches, that the joint action of variants in these 2 loci is consistent with independent ... en] OBJECTIVE: We studied the independent and joint effects of the genes encoding alpha-synuclein (SNCA) and microtubule- ...
Contribution of mindfulness in rheumatic joint disease
... Researchers at Diakonhjemmet Hospital, in Oslo, Norway, evaluated the ... Pain, fatigue, patient global disease activity, self-care ability and well-being were recorded at a 12-month follow-up. ... effects of a mindfulness-based group training in adults with inflammatory rheumatic joint diseases. ... No significant differences were found in emotional expression, pain, or disease activity. ...
5th E-Rare Joint Transnational Call for European Research Projects on Rare Diseases | ANR
5th E-Rare Joint Transnational Call for European Research Projects on Rare Diseases ... The submission and evaluation process will be managed by the E-Rare-2 Joint Call Secretariat (JCS) for the Joint Transnational ... Research proposals shall concern one or more rare diseases following the European definition (i.e. a disease affecting not more ... natural history of diseases, characterization of the genetic/molecular basis of specific diseases, etc. ...
DegenerativeOsteoarthritisArthritisRheumatoidMusculoskeletalEuropean Joint Programme on Rare DiseasesCartilageDeveloping Alzheimer's disease2021Autoimmune diseaseInflammationSevereCenters for DiseasArticularRare DiseasesImplicated in the pathogenesisInfectionMusclesInfectionsStiffnessSystemic diseaseSymptomsNeurologicalParkinson's DiseaseHeart diseaseRheumaticBoneDiagnosisPainPreventionBonesKnee joint2020Overuse of a jointDiabetesSeverity of joint diseaseVector-borne diseasesCoronavirus diseasePatientsDisordersGallbladder diseaseComplicationsElbow jointDisorderCardiovascular diseasesClinicalAlzheimer'sParkinson DiseaseTransmitting Lyme diseaseInflammatory diseasesAcuteTendernessSymptomaticPeriodontal disease
Degenerative13
- The product, launched by Alkem Laboratories in collaboration with Stempeutics, is indicated for the treatment of Knee Osteoarthritis, a degenerative disease of the joint. (financialexpress.com)
- An orthopaedic surgeon is a physician who specializes in diagnosis and surgical treatment of injuries and disorders involving the musculoskeletal system, such as hip replacements and arthroscopic knee surgery.In addition to treating trauma to the musculoskeletal system, these doctors also deal with sports injuries, degenerative diseases, infections, tumors and congenital disorders. (vitals.com)
- Degenerative joint disease, ventrodorsal projection, characterized by irregular bone margins in the joint. (msdvetmanual.com)
- Musculoskeletal disease (e.g., degenerative joint disease, osteoarthritis) is less well recognized in cats than in dogs. (dvm360.com)
- However, it is surprising how often degenerative joint disease is discovered as an incidental finding on feline radiographs. (dvm360.com)
- Joint diseases such as the degenerative joint disease osteoarthritis (OA) and the inflammatory disease rheumatoid arthritis (RA) are characterized by dramatic degradation of articular cartilage, caused by overexpression of matrix metalloproteinases (MMPs), and reduced anabolic activity of chondrocytes. (biomedcentral.com)
- Optimal approach against symptomatic degenerative joint disease and lower back pain. (pharmaevers.de)
- Demonstrated by numerous in vivo investigations: Inhibiting of cytokines (IL-1β, IL-6 and TNF-α) involved in the pathogenesis of degenerative joint disease and immune modulation. (pharmaevers.de)
- Find latest answers to Degenerative joint disease questions, Degenerative joint disease articles, Degenerative joint disease news and clinic/doctors who deal with Degenerative joint disease. (healcon.com)
- He treats all types of degenerative hip and knee diseases, as well as complications from past joint replacement. (ucsfhealth.org)
- I'm considering such things myself as my joint disease is degenerative.and I live alone. (answerbag.com)
- Traditionally, osteoarthritis was viewed as an inevitably progressive, degenerative disease process. (bmj.com)
- Osteoarthritis, a degenerative joint disease in which the cartilage wears away with age and bone rubs against bone, is the most common form of arthritis and affects about 27 million Americans. (everydayhealth.com)
Osteoarthritis14
- Knee Osteoarthritis is one of the most common debilitating diseases experienced within an ageing population and constitutes an urgent medical need. (financialexpress.com)
- StemOne has the potential to provide best-in-class pain reduction, improve quality of life, has the potential to maintain cartilage quality, and to stall further disease progression in Grade 2 and Grade 3 Osteoarthritis patients. (financialexpress.com)
- The safety, tolerability, and efficacy of HA (as intra-articular injection) have also been well-documented for treatment of various types of joint disease including knee osteoarthritic, joint osteoarthritis, canine osteoarthritis, and meniscal swelling. (nih.gov)
- In inflammatory joint disease, such as osteoarthritis or arthritis, there is an increased level of pro-inflammatory cytokines, such as interleukin-1β. (biomedcentral.com)
- A joint injury when you're young may cause osteoarthritis later in life. (medlineplus.gov)
- TMJ osteoarthritis (8 joints) and no pathology in 7 cases. (bvsalud.org)
- Osteoarthritis, the most common form of joint disease, is chiefly a disease of aging. (gafacom.website)
- Ninety percent of all people have radiographic features of osteoarthritis in weight-bearing joints by age 40. (gafacom.website)
- The paper also discusses the challenges for developing good quality outcome measures for use in large scale multicentre clinical trials for new osteoarthritis treatments, especially disease modifying osteoarthritis drugs. (bmj.com)
- 3 As a cause of disability (such as walking and stair climbing) in the elderly in the west, osteoarthritis is second only to cardiovascular disease. (bmj.com)
- Altogether 10%-15% of adults over 60 have some degree of osteoarthritis, and with an ageing population it is becoming an increasingly important disease. (bmj.com)
- Nalfon may be prescribed to treat a variety of conditions that include: osteoarthritis, rheumatoid arthritis, inflammatory joint disease, and gout. (northwestpharmacy.com)
- While pain relief medication can help manage symptoms of both conditions, osteoarthritis is not an inflammatory joint disease. (everydayhealth.com)
- Winston's Joint System and Winston's Pain Formula, two products for dogs developed by a naturopathic doctor, offer support and relief for many conditions affecting the joints, including hip dysplasia and osteoarthritis and rheumatoid arthritis, inflammatory diseases which also are common in dogs, attacking the cartilage, muscles and membrane linings of cartilage and joints. (dogshealth.com)
Arthritis35
- This allows them to treat arthritis, carpal tunnel, trigger finger and tennis elbow, most of which tend to result from repetitive and excessive use of the corresponding joints, muscles, tendons and ligaments. (vitals.com)
- Here, we investigated the role of autophagy during joint destruction in arthritis. (bmj.com)
- Rheumatoid arthritis (RA) is a chronic inflammatory disease that results in severe destruction of articular cartilage and bone. (bmj.com)
- Another major use of enzymes is to reverse inflammation of almost any kind just about anywhere in the body, especially in the joints (arthritis), the tendons (tendonitis) and the bursa (bursitis). (vitalitymagazine.com)
- CT and MRI of the neck showed calcification of the longus colli, fluid and capsular distention of C1-C2 joints, enhancement of the joint capsule and retropharyngeal oedema suggestive of septic arthritis. (bmj.com)
- Fluid was aspirated from C1 to C2 joint by interventional radiology and showed calcium pyrophosphate crystals and heavy MRSA colonisation, consistent with both pseudogout and septic arthritis of the cervical vertebrae. (bmj.com)
- Arthritis News : What is the Relationship of RA Disease Activity to Radiographic Progression of Joint Damage? (hopkinsarthritis.org)
- Here, Welsing et al ( Arthritis Rheum 50(7):2082, 2004 ) use GEE to investigate the longitudinal relationship of RA disease activity to radiographic damage in two different cohorts of RA patients. (hopkinsarthritis.org)
- Arthritis may cause joint pain and swelling. (medlineplus.gov)
- Over time, arthritis can cause severe joint damage. (medlineplus.gov)
- In psoriatic arthritis and ankylosing spondylitis, although cardiovascular disease is indeed important, it's actually within the spectrum of another comorbidity of that disease that we don't see in RA, which is metabolic syndrome. (medscape.com)
- The objective of this study is to examine and evaluate whether serum 25(OH)D is associated with disease activity in patients with rheumatoid arthritis (RA). (hindawi.com)
- Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterized by synovitis. (hindawi.com)
- Reduces stress on weight-bearing joints (extra pressure on some joints may aggravate your arthritis). (advancedorthosurgeons.com)
- Increasing muscle strength helps support and protect joints affected by arthritis. (advancedorthosurgeons.com)
- Individual joint rest is most helpful when arthritis involves one or only a few joints. (advancedorthosurgeons.com)
- Relieves arthritis-related joint pain, swelling and inflammation. (pharmaevers.de)
- Arthralgias and arthritis in BD mainly involve large joints (knees and ankles). (medscape.com)
- and (2) secondary, which may occur in any joint as a sequela to articular injury resulting from either intra-articular (includ-ing rheumatoid arthritis) or extra-articular causes. (gafacom.website)
- Lyme disease was first recognized in the United States in 1975, after a mysterious outbreak of arthritis near Lyme, Connecticut. (cdc.gov)
- Background Prokineticin 2 (PK2) manifestation is upregulated in mice with collagen-induced joint disease (CIA), an pet model of arthritis rheumatoid. (exposed-skin-care.net)
- In the light from the varied functions of neutrophils in the introduction of arthritis rheumatoid [20], these email address details are motivating for future research focusing on the precise mechanism from the PK2-PKR1 pathway in the pathogenesis of joint disease with this model. (exposed-skin-care.net)
- Nalfon is a nonsteroidal anti-inflammatory drug (NSAID) that is prescribed to relieve pain and reduce swelling and joint stiffness associated with various conditions, including arthritis. (northwestpharmacy.com)
- Psoriatic arthritis and rheumatoid arthritis (RA) are autoimmune diseases , in which the immune system mistakenly attacks healthy cells, causing swelling, pain, and stiffness in the joints. (everydayhealth.com)
- Psoriatic and rheumatoid arthritis are similar but separate diseases, sometimes with manifestations that look quite similar," says Mark Genovese, MD , the director of the rheumatology clinic at Stanford Health Care in Palo Alto, California. (everydayhealth.com)
- Last year, Diane Talbert of Waldorf, Maryland, who has lived with psoriatic disease for 30 years (she has psoriasis and psoriatic arthritis) was diagnosed with fibromyalgia , a disorder characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory, and mood issues. (everydayhealth.com)
- I know with my psoriatic arthritis I had pain also, along with swelling, but the tenderness is in certain joints. (everydayhealth.com)
- The problem is with Rheumatoid Arthritis being a disease that is misnamed and misunderstood. (rawarrior.com)
- Rheumatoid arthritis is characterized by pain, swelling and inflammation of the joints. (rawarrior.com)
- Order creams for joint pain, arthritis and arthritis in Portugal at an affordable price. (zdorov-cream.eu)
- In arthritis and arthritis diseases, the joints become inflamed and the cartilage tissue of the joints is affected. (zdorov-cream.eu)
- Zdorov, a cream used to treat joint pain, arthritis and arthritis, is one of the most effective drugs for treating joints. (zdorov-cream.eu)
- Arthritis of the knee joint develops slowly, and often develops in the context of sustained effects of traumatic factors. (zdorov-cream.eu)
- Rheumatoid arthritis is a chronic inflammatory disease that leads to pain, joint stiffness and swelling, and impaired hand function. (womenhealthexercise.com)
- The patient's medical history should be investigated with specific inquiry directed toward a personal history of cancer, arthritis, or infection or systemic disease that could increase risk of infection. (medscape.com)
Rheumatoid2
- This entry was posted on Friday, December 23rd, 2011 at 10:01 PM and is filed under Fatigue , Mindfulness , Pain , Rheumatoid Diseases . (thecamreport.com)
- Thanks for visiting this unique site full of information and encouragement to fight Rheumatoid Disease. (rawarrior.com)
Musculoskeletal2
- Turkish Joint Diseases Foundation is a supporting organization of Global Alliance for Musculoskeletal Health and member of International Osteoporosis Foundation . (jointdrs.org)
- Cream-wax is for external use and can be used in combination with other drugs to treat musculoskeletal diseases. (zdorov-cream.eu)
European Joint Programme on Rare Diseases1
- Insgesamt wurden im European Joint Programme on Rare Diseases (EJP RD 2019) 217 Anträge eingereicht, von denen 52 detailliert als Vollantrag vorgelegt wurden. (tu-dresden.de)
Cartilage10
- The results support the hypothesis that a copolymer of fatty acids, such as Ara 3000 beta®, is a powerful anti-inflammatory compounds, suggesting that it has a potential for preventing cartilage degradation associated with chronic inflammatory joint disease. (biomedcentral.com)
- The MMPs, produced by chondrocytes, are zinc-containing proteinases that degrade cartilage and cause severe joint damage. (biomedcentral.com)
- IL-1β also reduces levels of inhibitors of MMPs (tissue inhibitors of MMPs, TIMP) in arthritic joints and decreases biosynthesis of type II collagen and aggrecan, limiting the repair potential of cartilage. (biomedcentral.com)
- These effects have been confirmed by in vivo studies showing that intraarticular administration of IL-1β into animal joints causes proteoglycan loss from the cartilage, whereas injection of IL-1 receptor antagonist (IL-1ra) protects cartilage in arthritic joints. (biomedcentral.com)
- Cartilage is the hard slippery flexible tissue that covers the ends of your bones at a joint. (medlineplus.gov)
- The search for high quality implants initiated the research on cartilage replacement by hydrogels, which should assume the role of contact and friction in the joint implants. (anton-paar.com)
- Here we show the contribution of tribology, surface charge, and nanoindentation for characterization of polyvinyl alcohol hydrogel and porcine articular joint cartilage. (anton-paar.com)
- Hydrogels are considered as potential candidates for cartilage replacement because they are biocompatible and have mechanical properties similar to the joint cartilage [3] . (anton-paar.com)
- Such setup allows for characterization of cartilage replacement materials with lubrication fluids, comparing artificial with human joint cartilage, and to study the fundamentals of the lubrication mechanisms of cartilage. (anton-paar.com)
- Eliminate inflammation of joints and cartilage. (zdorov-cream.eu)
Developing Alzheimer's disease1
- The risk of developing Alzheimer's disease is higher among both Blacks and Latinos compared to whites, yet research studies disproportionately include white participants. (duke.edu)
20212
- On May 26, 2021 RDI met with the Oireachtas Joint Committee on Health. (rdi.ie)
- Posted by Leon Cai on Friday, December 10, 2021 in Dementia and Alzheimer's Disease , Diffusion Tensor Imaging , Diffusion Weighted MRI , Image Processing , Machine Learning , Magnetic resonance imaging , Neuroimaging , Tractography . (vanderbilt.edu)
Autoimmune disease5
- This autoimmune disease affects many parts of the body and can cause joint and muscle pain. (medlineplus.gov)
- This autoimmune disease affects glands that make moisture in many parts of the body. (medlineplus.gov)
- It's my body reacting to an autoimmune disease and attacking a joint. (medlineplus.gov)
- No one knows what causes vitiligo, but it may be an autoimmune disease. (nih.gov)
- Autoimmune disease affects 10% of adults, most of whom are women, and two of the top five medications with the highest cost globally are used to maintain these recurring conditions in remission. (hrb.ie)
Inflammation9
- The company claims that the existing treatment options focus on providing temporary pain relief and reducing inflammation during the early stages of the disease without affecting the course of the disease. (financialexpress.com)
- StemOne has anti-inflammatory and immunosuppressive properties which reduce inflammation in the knee joint. (financialexpress.com)
- Intra-articular injection of HA produces remarkable reduction in joint pain, synovial inflammation, and articular swelling. (nih.gov)
- The copolymer of fatty acids clearly reduces inflammation in joint. (biomedcentral.com)
- The main objective of drugs used in joint diseases, such as non steroidal anti-inflammatory drugs (NSAIDs), TNF-α inhibitors, or IL-1 receptor antagonists, is symptomatic management, reducing both pain and underlying inflammation [ 3 ]. (biomedcentral.com)
- May help reduce inflammation in joints. (advancedorthosurgeons.com)
- Short-term bed rest helps reduce both joint inflammation and pain, and is especially useful when multiple joints are affected and fatigue is a major problem. (advancedorthosurgeons.com)
- Joint effusion and other articular signs of inflammation are mild. (gafacom.website)
- Chronic inflammation of the joints. (encyclopedia.com)
Severe14
- The frequency of joint disease has been further reduced as increasing numbers of individuals with severe hemophilia have participated in prophylactic programs. (cdc.gov)
- Early recognition and joint stabilization can prevent severe DJD if either of these stifle problems are recognized early in the course. (dvm360.com)
- i am feeling so tired, and cough continued from last 6 month, not able to sleep, and feeling Stress, such as severe emotional and physical stress, and having joint pain also. (healcon.com)
- At transition, 24% of patients were in moderate to severe active phase of their disease and 40% of them had already been treated with ≥ 2 biologics. (unicatt.it)
- We also discovered that PK2 and PKR2 gene manifestation levels had been raised in the CIA bones which administration 694433-59-5 of PKRA7 suppressed the severe nature of joint disease. (exposed-skin-care.net)
- Furthermore, the amount of PKR2 gene manifestation was considerably correlated with the severe nature from the joint disease. (exposed-skin-care.net)
- Predicated on this statement, we given 15?mg/kg/day time of PKRA7 to CIA mice for 14?times from Day time 21 and discovered that PKRA7 significantly suppressed the severe nature of joint disease. (exposed-skin-care.net)
- Shira Shafir] We know that people with compromised or suppressed immune systems are more likely to get severe disease because their immune systems are not able to control the infection and this allows the fungus to spread from the lungs to other organs. (cdc.gov)
- Shira Shafir] While coccidioidomycosis has the potential to be severe and fatal, we believe that the number of deaths in the US associated with this disease are limited. (cdc.gov)
- Shira Shafir] When we see more people die in some groups as compared to others, we think it's either because certain groups are at an increased risk of exposure, they might have an increased risk of severe disease, or a combination of these two factors. (cdc.gov)
- In some populations, we suspect that possibility of death increases because poor access to health care services might delay diagnosis, resulting in more severe disease. (cdc.gov)
- Obesity is a risk factor for both susceptibility to infections including postoperative infections and other nosocomial infections and the occurrence of a more severe disease course. (hrb.ie)
- Severe disease requiring hospitalization is uncommon. (bvsalud.org)
- Hip dysplasia in Labradors is a genetic disease that can cause crippling, lameness and severe arthritic pain in a dog's joints. (dogshealth.com)
Centers for Diseas8
- Centers for Disease Control and Prevention. (cdc.gov)
- The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
- I'm Dr. Loretta Jackson-Brown and I'm representing the Clinician Outreach and Communication Activity, COCA in the Emergency Risk Communication Branch at the Centers for Disease Control and Prevention. (cdc.gov)
- Dr. Tauben and Dr. Robinson would like to disclose that their employer, the University of Washington, received a contract payment from the Centers for Disease Control and Prevention. (cdc.gov)
- Dr. Dowell is Senior Medical Advisor for the Division of Unintentional Injury Prevention and Control at the Centers for Disease Control and Prevention. (cdc.gov)
- The National Center for Health Statistics (NCHS) of the Centers for Disease Control and Prevention (CDC) collects, analyzes, and disseminates data on the health status of U.S. residents. (cdc.gov)
- According to the Centers for Disease Control and Prevention (CDC), doing some kind of physical activity or exercise on a regular basis helps to increase strength and flexibility, improve endurance, control weight, increase bone mass, and improve self-esteem, as well as reduce stress, anxiety, depression, and the risk of developing high blood pressure . (encyclopedia.com)
- Announcer] This program is presented by the Centers for Disease Control and Prevention. (cdc.gov)
Articular6
- There seems to be a spillover effect of the proinflammatory cytokines on the endothelial cells to the point where, I believe, premature atherosclerosis is an extra-articular manifestation of the disease. (medscape.com)
- The first question is what is an extra-articular manifestation of the disease, and what is the comorbidity. (medscape.com)
- When I think of comorbidities, I think of complications from the disease, whereas if I think about an extra-articular manifestation of the disease, it's almost like a different organ system has been targeted by the same disease process. (medscape.com)
- As I try to differentiate between the two, there's one common theme that arises: If you control the systemic disease process, you're very likely, although not always, to control either the comorbidity (if we want to term it that) or the extra-articular manifestations. (medscape.com)
- Diagnosis of bone and joint disorders, with emphasis on articular abnormalities / Donald Resnick, Gen Niwayama. (who.int)
- Alternatively, a global articular severity score (GASS) can be obtained by grading symptoms in each joint and summing the scores obtained in all joints. (biomedcentral.com)
Rare Diseases4
- The ANR joins the ERA-NET E-Rare-2 to launch a fifth call for proposals to fund transnational research projects on rare diseases. (anr.fr)
- Research proposals shall concern one or more rare diseases following the European definition (i.e. a disease affecting not more than five in 10.000 persons in the European Community). (anr.fr)
- The impact of the expected results on patients affected by rare diseases must be clearly stated. (anr.fr)
- We were joined at the meeting by Dr Sally Ann Lynch, Consultant Clinical Geneticist from Children's Health Ireland (CHI) at Crumlin and Ms Avril Daly, CEO at Retina International and VP at EURORDIS-Rare Diseases Europe. (rdi.ie)
Implicated in the pathogenesis1
- Dysregulation of autophagic pathways has recently been implicated in the pathogenesis of various diseases. (bmj.com)
Infection11
- WHO adopts vector control as part of its strategy to reduce infection rates and the spread of vector-borne diseases in the community. (who.int)
- WHO plays an active role in supporting countries to coordinate preparation efforts and so far has deployed more than 40 experts to ten countries to support coordination, treatment, infection, prevention and control, community engagement, surveillance and laboratory disease control. (who.int)
- According to data published in Open Forum Infectious Diseases , treatment nonresponse in prosthetic hip and knee joint infection (PJI) is common and the risk factors difficult to modify. (infectiousdiseaseadvisor.com)
- Investigators conducted a retrospective cohort of individuals who underwent prothesis removal as a result of a prosthetic joint infection at 5 Toronto, Canada, hospitals. (infectiousdiseaseadvisor.com)
- Treatment nonresponse was defined as recurrent prosthetic joint infection, amputation, death, or chronic antibiotic suppression and risk factors abstracted by chart review. (infectiousdiseaseadvisor.com)
- The investigators acknowledged that the detection strategy for prosthetic joint infection was imperfect and may have resulted in missed individuals. (infectiousdiseaseadvisor.com)
- Also, only individuals who underwent an operation for the treatment of prosthetic joint infection were included because the number of patients treated with antibiotics alone is expected to be small. (infectiousdiseaseadvisor.com)
- Lyme disease is an infection caused by Borrelia burgdorferi, a member of the family of spirochetes, or corkscrew-shaped bacteria. (cdc.gov)
- Tick larvae are smaller than the nymphs, but they rarely carry the infection at the time of feeding and are probably not important in the transmission of Lyme disease to humans. (cdc.gov)
- Adult ticks can transmit the disease, but since they are larger and more likely to be removed from a person's body within a few hours, they are less likely than the nymphs to have sufficient time to transmit the infection. (cdc.gov)
- The presence of fever, weight loss, anorexia, or abnormal blood tests should alert the physician to other disease processes such as infection or malignancy. (bmj.com)
Muscles9
- Strong muscles can protect joints from injury. (cdc.gov)
- Tendons are tough, flexible bands that connect your muscles to your bones so you can move your joints. (medlineplus.gov)
- It works as a pad between the bones of a joint and the moving parts around it, such as muscles, tendons and skin. (medlineplus.gov)
- Activity strengthens the muscles around your joints and helps them work better. (medlineplus.gov)
- Get the latest scientific news and resources on diseases of the bones, joints, muscles, and skin from the NIAMS. (nih.gov)
- Cardiac involvement is typically rare in late-onset Pompe disease (LOPD), whereas symptoms of LOPD are mainly related to progressive skeletal muscle dysfunction in the proximal lower limb and paraspinal trunk muscles that leads to progressive respiratory insufficiency and limb-girdle weakness. (medscape.com)
- Being physically active has also been proven to help build healthy bones, joints, and muscles. (encyclopedia.com)
- A healthy canine spheroidal joint controls this movement with the support of muscles, ligaments and tendons. (dogshealth.com)
- The muscles and joints become lax, and the joint capsule, a strong band of connective tissue which circled the bones for added stability, loses its elastic strength. (dogshealth.com)
Infections6
- Since then, additional reports have associated the organism with oral infections, specifically periodontal disease ( 2 - 5 ). (cdc.gov)
- Periprosthetic joint infections are a major complication after joint replacement. (cdc.gov)
- This trend is accompanied by an increase in the total number of periprosthetic joint infections, even though the overall percentage of this complication is low ( 7 ). (cdc.gov)
- The most commonly isolated organisms in periprosthetic joint infections are gram-positive cocci, specifically Staphylococcus aureus and S. epidermidis ( 8 ). (cdc.gov)
- Rather than focusing on the treatment of one disease or patient population, family practitioners are often the doctors that people see for their everyday ailments, like cold and flu or respiratory infections, and health screenings. (vitals.com)
- Standard diagnostic methods are not adequate to identify prosthetic joint infections (PJIs) in patients with rheumatic diseases, according to findings from a new study by researchers from Hospital for Special Surgery (HSS) in New York City. (brian-parsley.com)
Stiffness1
- Patients are usually over the age of 50 and complain of pain and stiffness in the affected joint(s), which is exacerbated with activity and relieved by rest. (bmj.com)
Systemic disease1
- it's a systemic disease. (rawarrior.com)
Symptoms7
- Although it is a well-known disorder, managing the disease is challenging for clinicians due to the variability in patients' bleeding symptoms and a lack of high-certainty evidence to guide treatment decisions. (hematologyadvisor.com)
- The main symptoms are dry eyes and mouth, but it often causes joint pain, too. (medlineplus.gov)
- Many people with Paget's disease do not have symptoms. (nih.gov)
- The most common symptoms of Zika virus disease are fever, rash, joint pain, and conjunctivitis (red eyes). (bvsalud.org)
- The effective effect of the drug allows you to resume physical activity, eliminate pain symptoms and overcome underlying diseases. (zdorov-cream.eu)
- Experts recommend using Zdorov cream immediately after the following symptoms: clenching during exercise, joint pain or discomfort. (zdorov-cream.eu)
- The review of systems should include assessments for fever, incontinence, symptoms suggestive of metastasis or metabolic disease, and psychological issues including depression and drug use or abuse. (medscape.com)
Neurological3
- Acute kidney injury (AKI) is a life-threatening disease with high mortality characterized by an abrupt decrease of the kidney glomerular filtration rate, extra-kidney consequences (cardiovascular diseases, lung injury, neurological impairment) and high risk of secondary chronic kidney disease (CKD). (hrb.ie)
- There may be some circulatory problems, joint disease, or neurological issues. (runtastic.com)
- Parkinson's disease (PD) is a relatively common neurological disease, affecting roughly 1% of the population over 60 years old [ 1 ]. (hindawi.com)
Parkinson's Disease2
- en] OBJECTIVE: We studied the independent and joint effects of the genes encoding alpha-synuclein (SNCA) and microtubule-associated protein tau (MAPT) in Parkinson disease (PD) as part of a large meta-analysis of individual data from case-control studies participating in the Genetic Epidemiology of Parkinson's Disease (GEO-PD) consortium. (uni.lu)
- Spine surgery in patients with Parkinson's disease (PD) involves increased risk. (hindawi.com)
Heart disease15
- They also work to help a patient maintain optimal health in order to prevent the onset of disease.In addition to treating the common cold and flu, internists also treat chronic diseases like diabetes and heart disease. (vitals.com)
- The risk of developing colon cancer, heart disease , high blood pressure , and diabetes is reduced through regular physical activity. (encyclopedia.com)
- NSAIDs such as Nalfon may increase the risk for a heart attack or stroke in people who have heart disease. (northwestpharmacy.com)
- Heart disease is the leading cause of death in the United States, causing about 1 in 4 deaths. (cdc.gov)
- In the United States, the most common type of heart disease is coronary artery disease (CAD, or ischemic heart disease), which can lead to heart attack. (cdc.gov)
- Several factors can be involved in the increased risk for heart disease. (cdc.gov)
- The Tracking Network uses data from the U.S. Census Bureau external icon , hospital and emergency department databases provided by state and/or local health departments, and death certificates from the National Center for Health Statistics to calculate state and local data about heart disease. (cdc.gov)
- Estimates of prevalence of heart attacks and ischemic heart disease are largely based on survey samples (e.g. (cdc.gov)
- These indicators provide information about health effects due to heart disease and stroke systems of care that informed policy interventions. (cdc.gov)
- These data come from hospitals, the Centers for Medicare and Medicaid Services external icon , and CDC's Atlas of Heart Disease and Stroke . (cdc.gov)
- These indicators used data collected by vital records from CDC's National Center for Health Statistics and CDC's Atlas of Heart Disease and Stroke . (cdc.gov)
- Data can be used to identify trends and patterns in the mortality of ischemic heart disease, heart attacks, or stroke. (cdc.gov)
- This data can be used to identify trends in the mortality of heart disease (heart attack, coronary heart disease). (cdc.gov)
- These indicators include data on the crude and age-adjusted rate of coronary heart disease and the prevalence of adults ever diagnosed with stroke. (cdc.gov)
- During the last decades 62-65% of all deaths in our country are due to cardiovascular disease (coronary heart disease, hy- pertension, stroke) and Bulgaria is one of the leaders in the world by mortality rate of stroke. (bvs.br)
Rheumatic1
- Researchers at Diakonhjemmet Hospital, in Oslo, Norway, evaluated the effects of a mindfulness-based group training in adults with inflammatory rheumatic joint diseases. (thecamreport.com)
Bone6
- The Center For Bone And Joint Disease is a Practice with 1 Location. (vitals.com)
- Currently The Center For Bone And Joint Disease's 16 physicians cover 12 specialty areas of medicine. (vitals.com)
- View all providers that belong to The Center For Bone And Joint Disease. (vitals.com)
- Paget's disease of bone is a chronic (long-lasting) disorder that causes bones to grow larger and become weaker than normal. (nih.gov)
- This is called a "spheroidal" joint, referring to the spherical head of the distal or articulating bone, which fits into the cup-like cavity of the accompanying bone. (dogshealth.com)
- The underlying joints and bone are spared. (medscape.com)
Diagnosis5
- A systematic analysis and generalization of scienti !c information of Ukrainian scientists about planning of the stages of diagnosis of patients with TMJ diseases , which will allow to optimize the commonly accepted examination algorithm . (bvsalud.org)
- Scienti !c analysis and generalization of obtained data of literary sources of Ukrainian scientists articles with characteristics of planning stages of diagnosis of patients with TMJ diseases is based on such databases as Scopus, Web of Science , MedLine , PubMed , NCBI, the study of which does not exceed 6 years, including monographs and results clinical research . (bvsalud.org)
- The results of scienti !c research by Ukrainian scientists are the basis for increasing the effectiveness of diagnosis of TMJ diseases by improving complex examination methods and implementing clinical algorithms , which will allow to choose adequate treatment methods . (bvsalud.org)
- After complete this course participants will be able to diagnosis peripheral joints problem and will be able to set the goals and treatment protocol independently for the betterment of patients. (aopbd.org)
- The VASCERN project aims to facilitate and improve diagnosis, treatment and care for ALL patients suffering from Rare Multisystemic Vascular Diseases, thus enhancing access to care, and improving quantity and quality of life of these patients. (lvts.fr)
Pain19
- As this population ages, the associated disabilities and pain from joint disease have become pressing concerns for many patients. (cdc.gov)
- If the source of the pain is orthopedic disease, the gait may become stilted and the cat may assume very awkward positions when jumping up or down. (dvm360.com)
- Occasionally, a cat will have one painful limb and exhibit an obvious limp, but more commonly, the pain is from bilateral orthopedic disease, spinal disease, or a non-orthopedic cause. (dvm360.com)
- Pain, fatigue, patient global disease activity, self-care ability and well-being were recorded at a 12-month follow-up. (thecamreport.com)
- No significant differences were found in emotional expression, pain, or disease activity. (thecamreport.com)
- They often cause joint pain and make your joints stiff, red, or swollen. (medlineplus.gov)
- The severity of joint disease in JIA can be quantified by counting the number of joints with swelling, tenderness/pain on motion, and restricted motion, and by calculating, through these parameters, the number of active joints (NAJ). (biomedcentral.com)
- Cold Therapy - cold packs, ice massage, OTC sprays and ointments (reduces pain by numbing the nerves around the joint). (advancedorthosurgeons.com)
- Contains a well proven medicinal plant that has been traditionally used for decades to treat chronic lower back and joint pain. (pharmaevers.de)
- I am feeling pain in the right knee joint. (healcon.com)
- will have to clear whether the pain arising is from back and referred to knee and foot, or is solely knee joint pain. (healcon.com)
- I have joint pain in my RHS arm. (healcon.com)
- this develops later into pain on motion of the affected joint and is made worse by activity or weight bearing and relieved by rest. (gafacom.website)
- For a response of ACR20, there had to be ≥20% improvement in swollen joint count, ≥20% improvement in painful/tender joint count, and ≥20% improvement in at least 3 of the following: subject's assessment of pain, global assessment of disease activity, assessment of physical function, or acute phase reactant (C-reactive protein or erythrocyte sedimentation rate). (clinicaltrials.gov)
- In order to recover the full functionality of the joint and to relieve the patient's pain, the joint implants should fulfill the same function as the original body parts. (anton-paar.com)
- They also may have joint and muscle pain. (nih.gov)
- It goes without saying that this elimination of unhealthy fat helps reduce the risks of diseases like obesity, joint pain, diabetes, etc. (alaskamagazine.com)
- Many different things can cause neck pain, including injury, age-related disorders, and inflammatory disease. (lowellgeneral.org)
- Neck pain can result from many different causes, including injury, age-related disorders, and inflammatory disease. (lowellgeneral.org)
Prevention5
- When necessary, family practitioners will provide referrals for conditions that require the expertise of another specialist.The doctors may also provide physicals, inoculations, prenatal care, treat chronic diseases, like diabetes and asthma, and provide advice on disease prevention. (vitals.com)
- Prevention of radiographic progression of joint damage has thus become a goal of treatment, and an outcome for many clinical trials. (hopkinsarthritis.org)
- Diet, nutrition and the prevention of chronic diseases. (bvsalud.org)
- At that time, the rapid rise in coronavirus cases - both within the country and among travelers - was so concerning, a joint WHO and European Center for Disease Prevention and Control mission went to Italy to figure out what was going on. (vox.com)
- Experts recommend joint prevention as early as possible. (zdorov-cream.eu)
Bones9
- Your joints are places where two or more bones come together. (medlineplus.gov)
- But joints are more than bones. (medlineplus.gov)
- Ligaments connect the bones of the joint to each other to keep them stable when you move. (medlineplus.gov)
- A joint is dislocated when the bones are pushed or pulled out of position. (medlineplus.gov)
- Usually only one or a few bones have the disease. (nih.gov)
- Problems in the joints near the bones with the disease. (nih.gov)
- In simple terms, the two bones of the hip joint shift out of alignment. (dogshealth.com)
- The structure of a dog's hip bones is similar to our human hip formation, consisting of a precisely fitted ball-and-socket joint. (dogshealth.com)
- The bones slowly separate as the soft tissues around the joint degenerate. (dogshealth.com)
Knee joint1
- when you hear sound like tuk while folding or unfolding ie bending and straightening your knees, that means your popliteus muscle ie behind the knee joint is weak and complete load is taken by the meniscus or ligament supporting the knee. (healcon.com)
20201
- Addis Ababa, 22 February 2020 - As the threat of coronavirus disease looms over the continent, the World Health Organization (WHO) promised to support African Union Member States on a common preparedness and response strategy. (who.int)
Overuse of a joint2
- Injuries can happen because of overuse of a joint. (medlineplus.gov)
- or chronic, as that due to occupational overuse of a joint or metabolic disease (eg, hyperparathyroidism, hemochromatosis, ochronosis). (gafacom.website)
Diabetes1
- The overconsumption of high energy foods and low physical activity contribute substantially to the high prevalence of obesity - risk factor for diabetes type 2, high blood pressure, cardiovascular disease etc. (bvs.br)
Severity of joint disease1
- Factor concentrates, home treatment, physical therapy, and orthopedic surgery have contributed to decreased frequency and severity of joint disease among people with hemophilia during the past 25 years. (cdc.gov)
Vector-borne diseases2
- To effectively reduce the sources of vectors and reduce potential impacts of vector borne diseases, the WHO is supporting the Ministry of Health conduct a community-based vector control campaign. (who.int)
- The main objective of the campaign is that by its end, there will be a considerable decrease in malaria and other vector-borne diseases, in addition to stronger community engagement in adopting preventive and protective measures to decrease the likelihood of the regeneration of mosquito and other vector breeding sites. (who.int)
Coronavirus disease1
- WHO joined Health Ministers in an Emergency Meeting on the Coronavirus Disease Outbreak, which was convened on 22 February by the African Union Commission in Addis Ababa, Ethiopia. (who.int)
Patients18
- Unfortunately, most of these patients still develop at least one chronic joint in their lifetimes. (cdc.gov)
- StemOne offers a novel treatment approach to the physicians in India to treat Knee OA and will substantially improve the quality of life of millions of patients suffering from this painful disease," Sunil Pathak - Senior Vice President & Cluster Head at Alkem said in a statement. (financialexpress.com)
- Patients are treated according to the discretion of their treating rheumatologist, but have regular assessments of disease activity (reported as DAS (disease activity scores) collected at baseline and every 3 months) and radiographs of hands and feet obtained at baseline and every three years. (hopkinsarthritis.org)
- The baseline characteristics of patients enrolled in each of the cohorts was remarkably similar except that the COBRA group had higher disease activity at baseline (as required by the study protocol) and was followed for a longer period of time. (hopkinsarthritis.org)
- Patients with type 3 VWD may experience joint bleeds similar to those seen in patients with hemophilia. (hematologyadvisor.com)
- Patients with psoriatic disease are much more likely to have metabolic syndrome. (medscape.com)
- Thirty-four JIA patients underwent a standardized joint assessment and had both NAJ and GASS calculated. (biomedcentral.com)
- Based on the serum 25(OH)D levels, patients with RA were divided into inadequate group and normal group, and there were no significant differences in baseline characteristics and disease activity in the two groups. (hindawi.com)
- However, no correlations were found between 25(OH)D levels and disease activity among 116 patients with RA. (hindawi.com)
- Thus, the objective of this study was performed to analyze the 25(OH)D levels in RA patients and healthy people and investigate the association between the serum levels of 25(OH)D 3 and disease activity of RA patients from Southwest China. (hindawi.com)
- Joint involvement affects approximately 50% of patients with BD. (medscape.com)
- Gastrointestinal involvement, characterized by multiple ulcers similar to inflammatory bowel disease, is an important complication of BD that is more prevalent among patients from countries in the Far East. (medscape.com)
- He also performs unicompartmental or partial knee replacements, an effective procedure used with patients whose joint destruction involves only one compartment of the knee. (brian-parsley.com)
- Both patients had keratosulfaturia, mild thorax changes, and corneal clouding, although they did not show unique pectus carinatum, genu valgum, excessive joint laxity, or facial changes. (medscape.com)
- Background: Transition from pediatric to adult care of patients affected by Inflammatory Bowel Disease (IBD) is a critical step that needs specific care and multidisciplinary involvement. (unicatt.it)
- While there is evidence some treatments can slow disease progress in some patients, implying that treatment prevents damage is an overstatement. (rawarrior.com)
- Ten RA patients were assessed twice by five rheumatologists performing BM and PD scoring (0-3) of 16 joints bilaterally (metacarpophalangeal 1-5, wrist (radiocarpal, intercarpal, radioulnar), elbow, knee, talocrural and metatarsophalangeal 1-5), with the novel ultrasonographic atlas as a reference. (bmj.com)
- Patients with a surgical history of lumbar arthrodesis, lumbar diskectomy, or lumbar laminectomy have changes in lumbar spine biomechanics resulting in susceptibility to diskogenic disease. (medscape.com)
Disorders6
- What are joint disorders? (medlineplus.gov)
- Joint disorders are diseases or injuries that affect your joints. (medlineplus.gov)
- What types of joint disorders happen from sudden injuries? (medlineplus.gov)
- What types of joint disorders happen from overuse? (medlineplus.gov)
- Getting enough physical activity is one of the most important things you can do to prevent or slow joint disorders. (medlineplus.gov)
- On the other side, undernutrition causes nutritional deficiencies that provoke immunity disorders and elevated risk for infectious diseases. (bvs.br)
Gallbladder disease7
- Separate and joint effects of alcohol and smoking on the risks of cirrhosis and gallbladder disease in middle-aged women. (ox.ac.uk)
- The separate and joint effects of alcohol and smoking on incidences of liver cirrhosis and gallbladder disease were examined in a prospective study of 1,290,413 United Kingdom women (mean age, 56 years) recruited during 1996-2001. (ox.ac.uk)
- After a mean follow-up of 6.1 years (1996-2005), incidence rates of cirrhosis and gallbladder disease were 1.3 per 1,000 persons (n = 2,105) and 15 per 1,000 persons (n = 23,989), respectively, over 5 years. (ox.ac.uk)
- or =15 units/week with those who drank 1-2 units/week, the relative risk was 4.32 (95% confidence interval (CI): 3.71, 5.03)) for cirrhosis and 0.59 (95% CI: 0.55, 0.64) for gallbladder disease. (ox.ac.uk)
- or =20 cigarettes/day with never smokers, the relative risk was 3.76 (95% CI: 3.25, 4.34) for cirrhosis and 1.29 (95% CI: 1.22, 1.37) for gallbladder disease. (ox.ac.uk)
- Effects of alcohol and smoking were more than multiplicative for cirrhosis (P(interaction) = 0.02) but not for gallbladder disease (P(interaction) = 0.4). (ox.ac.uk)
- For gallbladder disease, alcohol reduces risk and smoking results in a small risk increase. (ox.ac.uk)
Complications2
- His expertise encompasses the direct anterior approach (a minimally invasive hip replacement technique), outpatient surgery for hip and knee replacement, partial knee replacement, complex revision surgery (surgery to restore joint function when an implant has failed or developed complications) and robotic surgery. (ucsfhealth.org)
- however, complications may include skeletal and joint disease. (medscape.com)
Elbow joint1
- in the wrist joint mostly but also the elbow joint plus the finger joints. (healcon.com)
Disorder2
- The most common inherited bleeding disorder, von Willebrand disease (VWD), is characterized by defective platelet adhesion and aggregation. (hematologyadvisor.com)
- Learn about root causes of thyroid disorder, advanced lab testing, proper interpretation and treatment that helps people reverse their thyroid disease and become medication and symptom free. (mindbodyfunctionalmedicine.com)
Cardiovascular diseases1
- 25-hydroxyvitamin D [25(OH)D], the accepted measure of vitamin D status, has been linked to several pathological states, including cardiovascular diseases, inflammatory disease, and high all-cause mortality in the general population [ 1 ]. (hindawi.com)
Clinical4
- The Journal welcomes original clinical and empirical scientific research articles, reviews and case reports ( limited number ) or clinical pictures ( limited number ) about joint diseases and related surgery, arthroplasty, arthroscopy, general orthopedics and traumatology written only in English . (jointdrs.org)
- Through our cancer collaboration you'll have access to distinguished disease-specific treatment capabilities, expanded clinical trial enrollment and precision medicine offerings, close to home. (johnmuirhealth.com)
- The joint cancer network will provide distinguished disease-specific treatment capabilities, expanded clinical trial enrollment and precision medicine offerings. (johnmuirhealth.com)
- Acticor Biotech, a clinical stage biotechnology company (raised on the basis of a work initiated in Team 6 of U1148) involved in the acute phase of thrombotic diseases, including stroke and myocardial infarction, today announced the agreement of Dutch Authorities for the initiation of a phase I clinical trial in healthy volunteers with its drug candidate, ACT017. (lvts.fr)
Alzheimer's6
- Duke University and the University of North Carolina at Chapel Hill have been awarded funds from the National Institutes of Health to establish a prestigious Alzheimer's Disease Research Center (ADRC), part of a federally-funded national network of similar centers. (duke.edu)
- Whitson and Garden said the NIH funding will enable teams from both institutions to engage local communities with new hypotheses about Alzheimer's disease. (duke.edu)
- This project would help identify new biomarkers of Alzheimer's disease, understand key biological changes that precede the onset of disease, and potentially identify targets for new therapies. (duke.edu)
- Characterizing relationships between gray matter (GM) and white matter (WM) in early Alzheimer's disease (AD) would improve understanding of how and when AD impacts the brain. (vanderbilt.edu)
- Alzheimer's Disease Related Dementias (ADRD). (neurodegenerationresearch.eu)
- Repeated occurrences of microvascular ischemia reportedly lead to white matter hyperintensities, focal brain infarcts, and brain atrophy that contribute to cognitive impairment and the risk of mild cognitive impairment (MCI) and Alzheimer's disease-related dementias. (neurodegenerationresearch.eu)
Parkinson Disease1
- Independent and joint effects of the MAPT and SNCA genes in Parkinson disease. (uni.lu)
Transmitting Lyme disease1
- The deer (or bear) tick, Ixodes dammini, which normally feeds on the white-footed mouse, the white-tailed deer, other mammals, and birds, is responsible for transmitting Lyme disease bacteria to humans in the northeastern and north-central United States. (cdc.gov)
Inflammatory diseases1
- For instance, long chain n-3 fatty acids are present in fish and marine mammals, and epidemiological data indicate a correlation between fish-wealthy diets and reduced incidence of inflammatory diseases [ 6 ]. (biomedcentral.com)
Acute1
- Splinting can be used for a short time to immobilize the affected joint during the acute phase of a bleed. (cdc.gov)
Tenderness1
- Joint tenderness and crepitus on movement may also be present. (bmj.com)
Symptomatic2
- Current Knee OA treatments are more symptomatic in nature whereas StemOne drug has the potential to address the root cause of the disease. (financialexpress.com)
- Symptomatic disease also increases with age. (gafacom.website)
Periodontal disease1
- While B. extructa 's association with human periodontal disease is well documented, the bacterium has so far not been implicated in other pathogenic processes. (cdc.gov)