Infection with parasitic protozoa of the genus ISOSPORA, producing intestinal disease. It is caused by ingestion of oocysts and can produce tissue cysts.
A genus of protozoan parasites found in the intestines of birds, amphibians, reptiles, and mammals, including man. The oocysts produce two sporocysts, each with four sporozoites. Many species are parasitic in wild and domestic animals.

Differential effects of endoparasitism on the expression of carotenoid- and melanin-based ornamental coloration. (1/23)

The striking diversity of sexual dimorphisms in nature begs the question: Why are there so many signal types? One possibility is that ornamental traits convey different sets of information about the quality of the sender to the receiver. The colourful, pigmented feathers of male birds seem to meet the predictions of this hypothesis. Evidence suggests that carotenoid pigmentation reflects the nutritional condition of males during moult, whereas in many instances melanin pigmentation is a reliable indicator of social status. However, as of yet there have been no experimental tests to determine how these two ornament types respond to the same form of environmental stress. In this study, we tested the effect of endoparasitic infection by intestinal coccidians (Isospora sp.) on the expression of both carotenoid- and melanin-based ornamental coloration in captive male American goldfinches (Carduelis tristis). We found that the carotenoid-based plumage and bill coloration of parasitized males was less saturated than that developed by unparasitized males, but that the brightness and size of melanin-based black caps did not differ between the groups. These findings provide the most robust empirical support to date for the notion that carotenoid and melanin ornaments reveal different information to conspecifics.  (+info)

Case report: Nitazoxanide treatment failure in chronic isosporiasis. (2/23)

We report a 60-year-old immunocompetent patient with chronic biliary isosporiasis who failed to respond to orally administered cotrimoxazole prophylaxis and orally administered treatment with nitazoxanide, a 5-nitrothiazole benzamide compound. Severe malabsorption was regarded as responsible for the subtherapeutic levels of nitazoxanide in plasma and bile, resulting in treatment failure. Intravenously administered cotrimoxazole stopped the shedding of Isospora belli oocysts in bile within 5 days, excluding initially suspected resistance to cotrimoxazole. Patients with malabsorption and cholangitis due to Coccidia such as Isospora belli and Cryptosporidium spp. or due to protozoa that cause microsporidiasis seem to be predisposed to fail to respond to otherwise effective treatment.  (+info)

An outbreak of adenoviral infection in inland bearded dragons (Pogona vitticeps) coinfected with dependovirus and coccidial protozoa (Isospora sp.). (3/23)

Thirty of 200 (15%) hatchling inland bearded dragons were found dead after a short period (48 hours) of weakness and lethargy. The most common clinical signs were head tilt and circling. Six bearded dragons with neurological signs were euthanized, and postmortem examination revealed no gross abnormalities. Microscopically, severe, randomly distributed hepatocellular necrosis with large basophilic intranuclear inclusion bodies in numerous hepatocytes was noted. Small-intestinal enterocytes contained intracytoplasmic coccidial protozoa (Isospora sp.) and occasional enterocytes had basophilic intranuclear inclusion bodies. Transmission electron microscopy revealed both 80- and 20-nm-diameter viral particles, which were consistent with adenoviruses and dependoviruses, respectively. Adenoviral outbreaks in groups of animals are uncommon. An adverse synergistic effect of the coccidiosis with the adenoviral infection may have played a critical role in the high morbidity and mortality in this case.  (+info)

Isosporiasis in Venezuelan adults infected with human immunodeficiency virus: clinical characterization. (4/23)

A cross-sectional study was undertaken to determine the prevalence of isosporiasis and its clinical and laboratory pattern in Venezuelan patients infected with human immunodeficiency virus (HIV) (n = 397). At enrollment, they underwent a thorough clinical history and physical examination, and provided stool specimens for the identification of Isospora belli and other parasites. Isospora belli was identified in 56 subjects (14%) and diarrhea, either acute or chronic, was present in 98% of these cases (P < 0.001). Eosinophilia was strongly associated with isosporiasis (P = 0.01). It was also found that the presence of eosinophilia was more common in I. belli-infected patients without weight loss (P < 0.001). Twenty-six (81.25%) subjects with I. belli infection had CD4+ cell counts < 200 cells/mm3 (P = 0.03). In addition, the data and its description shows the association to be < 100 cells/mm3. This infection seems to be seasonal because the recovery of oocysts occurred mainly in months with significant rainfall. In fact, isosporiasis should be suspected in HIV-infected patients from tropical countries with diarrhea, weight loss, eosinophilia, and low CD4+ cell counts.  (+info)

Point prevalence of Cryptosporidium, Cyclospora, and Isospora infections in patients being evaluated for diarrhea. (5/23)

From March to September 2001, 315 specimens from "nonrepeat" patients that were submitted for ova and parasite examination were stained using the Kinyoun modified acid-fast stain to detect the intestinal coccidians. Four patients (1.3%) were infected with coccidians, 2 with Cryptosporidium parvum and 2 with Cyclospora cayetanensis. No infections with Isospora belli were detected. In comparison, 15 patients (4.8%) had infections with one or more intestinal parasites detected by routine trichrome staining: 5 had Giardia lamblia; 2, Dientamoeba fragilis; 3, Strongyloides stercoralis; 1, Iodamoeba butschlii; 3, Endolimax nana; 6, Blastocystis hominis; and 1, Entamoeba coli. Four patients were multiply infected. Coccidians made up 29% of the clinically significant parasitic infections. The coccidians were missed in all 4 cases because no special staining was ordered. Clinicians need to be reminded that additional tests should be ordered to fully evaluate patients with chronic diarrhea in which no diagnosis is found by routine testing.  (+info)

Endometrial coccidiosis. (6/23)

This report describes a case of granulomatous endometritis caused by coccidiosis in an immunologically uncompromised 63 year old patient. The glandular epithelium of the endometrium contained numerous intracytoplasmic cysts, corresponding to periodic acid Schiff positive and methenamine silver negative sporoblasts. The endometrial glands revealed reactive phenomena, such as eosinophilic and squamous glandular metaplasia and intraluminal desquamation. Non-necrotising epithelioid granulomata, lacking the presence of parasites, were present in the stroma. Although not detected in the stool examination, the organisms were probably Isospora belli. There was no evidence of other foci of the disease. Coccidiosis should be differentiated from the more commonly occurring coccidiomycosis.  (+info)

Prevalence of intestinal parasites including microsporidia in human immunodeficiency virus-infected adults in Cameroon: a cross-sectional study. (7/23)

To assess the prevalence of intestinal parasites in a cohort of human immunodeficiency virus (HIV)-infected adults in Cameroon, a cross-sectional study was conducted. Detection of parasites was performed in 181 stool samples from 154 HIV-infected patients with a mean CD4 cell count of 238 cells/mm(3). Only 35 patients (22%) were receiving antiretroviral therapy at the time of stool sampling, and 46 (29%) had diarrhea. Opportunistic protozoa were found in 15 patients (9.7%), 8 of whom (53%) had diarrhea. Enterocytozoon bieneusi was found in eight patients, C. parvum in six patients, and Isospora belli in three patients. All E. bieneusi isolates tested belonged to the same genotype. The prevalence of opportunistic protozoa among patients with CD4 cell counts less than 50/mm(3) was 32%.  (+info)

Case report: Isospora belli infection in a renal transplant recipent. (8/23)

Isospora belli, an opportunistic protozoon, is one of the most commonly recognized causes of diarrhea in patients with acquired immunodeficiency syndrome (AIDS). Infection is acquired through fecal contaminated food or water, and generally diagnosed by examination of stool and/or duodenum biopsy specimens with acid-fast staining. Here, we present an uncommon case, chronic diarrhea caused by I. belli infection in a patient who is a renal transplant recipient.  (+info)

Isosporiasis is a gastrointestinal infection caused by the protozoan parasite Isospora belli. It is characterized by watery diarrhea, abdominal cramps, nausea, and fever. The infection is typically spread through the fecal-oral route, often through contaminated food or water. Immunocompromised individuals, such as those with HIV/AIDS, are at an increased risk for severe and chronic infections. Diagnosis is made through identification of the parasite's oocysts in stool samples. Treatment typically involves the use of antiprotozoal medications such as trimethoprim-sulfamethoxazole (TMP-SMX).

Isospora is a genus of protozoan parasites that belong to the phylum Apicomplexa. These parasites are the causative agents of coccidiosis, a type of gastrointestinal infection that primarily affects birds and mammals, including humans. The disease is characterized by watery diarrhea, abdominal pain, vomiting, and weight loss.

Isospora species have a complex life cycle that involves two hosts: an intermediate host, where the parasite reproduces asexually, and a definitive host, where the parasite undergoes sexual reproduction. The infectious stage of the parasite is called an oocyst, which is shed in the feces of the infected host and can survive in the environment for long periods. When ingested by another host, the oocyst releases sporozoites, which invade the intestinal cells and multiply, causing damage to the intestinal lining and leading to the symptoms of coccidiosis.

In humans, Isospora belli is the most common species that causes infection. It is typically transmitted through the fecal-oral route, either by ingesting contaminated food or water or by person-to-person contact. Immunocompromised individuals, such as those with HIV/AIDS, are at higher risk of developing severe and chronic infections with Isospora. Treatment usually involves the use of antiprotozoal drugs, such as trimethoprim-sulfamethoxazole.

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It is responsible for the condition isosporiasis, which causes acute, non-bloody diarrhoea in immunocompromised individuals. At ...
Human cyclosporiasis is clinically similar to cryptosporidiosis, isosporiasis, giardiasis and microsporidiosis because of the ...
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... isosporiasis MeSH C03.752.250.552 - malaria MeSH C03.752.250.552.606 - malaria, avian MeSH C03.752.250.552.620 - malaria, ...
Isosporiasis Archived 2008-09-16 at the Wayback Machine at the CDC website. Lagrange-Xélot M, Porcher R, Sarfati C, et al. ( ... February 2008). "Isosporiasis in patients with HIV infection in the highly active antiretroviral therapy era in France". HIV ... Isosporiasis, also known as cystoisosporiasis, is a human intestinal disease caused by the parasite Cystoisospora belli ( ... Isosporiasis). Good hand-washing, and personal-hygiene practices should be used as well. One should wash their hands with soap ...
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Isosporiasis. Eating contaminated food or water can cause an isosporiasis infection. In those with HIV, symptoms of ...
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Cryptosporidiosis, isosporiasis, microsporidiosis, cyclosporiasis. Infect Dis Clin North Am. 1993 Sep. 7(3):569-86. [QxMD ...
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ICD-10 code B60.8 for Other specified protozoal diseases is a medical classification as listed by WHO under the range -Protozoal diseases .
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  • Isosporiasis, also known as cystoisosporiasis, is a human intestinal disease caused by the parasite Cystoisospora belli (previously known as Isospora belli). (wikipedia.org)
  • citation needed] Typical laboratory analyses include:[citation needed] Microscopy Morphologic comparison with other intestinal parasites Bench aids for Cystoisospora Avoiding food or water that may be contaminated with stool can help prevent the infection of Cystoisospora (Isosporiasis). (wikipedia.org)
  • Although treatment has been available for several decades for giardiasis, isosporiasis and amoebiasis, until recently there have been no effective remedies for infection with intestinal coccidia--Cryptosporidium, Microsporidium and Cyclospora species. (qxmd.com)
  • As part of his masters research project, Dylan used molecular techniques to investigate the occurrence of systemic isosporiasis, a potentially fatal parasitic infection, in British garden birds. (rvc.ac.uk)
  • Cystoisosporiasis (formerly isosporiasis) is caused by Cystoisospora belli (erstwhile named Isospora belli) is encountered globally, particularly in tropical and subtropical regions. (microbiochemjournal.com)
  • It is used for the treatment of toxoplasmosis, actinomycosis, and isosporiasis, and for the treatment and prevention of Pneumocystis jirovecii pneumonia. (southdelhipharma.com)
  • Cystoisosporiasis (formerly known as isosporiasis) is an intestinal disease of humans caused by the coccidian parasite Cystoisospora belli (formerly known as Isospora belli ). (cdc.gov)
  • Isosporiasis, also known as cystoisosporiasis, is a human intestinal disease caused by the parasite Cystoisospora belli (previously known as Isospora belli). (wikipedia.org)
  • Group A was 124 mocystis carinii pneumonia or isosporiasis would be valuable. (cdc.gov)