Myocardial Bridging: A malformation that is characterized by a muscle bridge over a segment of the CORONARY ARTERIES. Systolic contractions of the muscle bridge can lead to narrowing of coronary artery; coronary compression; MYOCARDIAL ISCHEMIA; MYOCARDIAL INFARCTION; and SUDDEN CARDIAC DEATH.Coronary Vessel Anomalies: Malformations of CORONARY VESSELS, either arteries or veins. Included are anomalous origins of coronary arteries; ARTERIOVENOUS FISTULA; CORONARY ANEURYSM; MYOCARDIAL BRIDGING; and others.Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.Coronary Angiography: Radiography of the vascular system of the heart muscle after injection of a contrast medium.Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.Takotsubo Cardiomyopathy: A transient left ventricular apical dysfunction or ballooning accompanied by electrocardiographic (ECG) T wave inversions. This abnormality is associated with high levels of CATECHOLAMINES, either administered or endogenously secreted from a tumor or during extreme stress.Cardiomyopathy, Hypertrophic: A form of CARDIAC MUSCLE disease, characterized by left and/or right ventricular hypertrophy (HYPERTROPHY, LEFT VENTRICULAR; HYPERTROPHY, RIGHT VENTRICULAR), frequent asymmetrical involvement of the HEART SEPTUM, and normal or reduced left ventricular volume. Risk factors include HYPERTENSION; AORTIC STENOSIS; and gene MUTATION; (FAMILIAL HYPERTROPHIC CARDIOMYOPATHY).Multidetector Computed Tomography: Types of spiral computed tomography technology in which multiple slices of data are acquired simultaneously improving the resolution over single slice acquisition technology.Ultrasonography, Interventional: The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.Coronary Vessels: The veins and arteries of the HEART.Coronary Circulation: The circulation of blood through the CORONARY VESSELS of the HEART.Electrocardiography: Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.Autopsy: Postmortem examination of the body.Death, Sudden, Cardiac: Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)Constriction, Pathologic: The condition of an anatomical structure's being constricted beyond normal dimensions.Reperfusion Injury: Adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to the tissue (REPERFUSION), including swelling; HEMORRHAGE; NECROSIS; and damage from FREE RADICALS. The most common instance is MYOCARDIAL REPERFUSION INJURY.Myocardium: The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.Blood Flow Velocity: A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.Echocardiography: Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.Privacy: The state of being free from intrusion or disturbance in one's private life or affairs. (Random House Unabridged Dictionary, 2d ed, 1993)Confidentiality: The privacy of information and its protection against unauthorized disclosure.Computer Security: Protective measures against unauthorized access to or interference with computer operating systems, telecommunications, or data structures, especially the modification, deletion, destruction, or release of data in computers. It includes methods of forestalling interference by computer viruses or so-called computer hackers aiming to compromise stored data.Informed Consent: Voluntary authorization, by a patient or research subject, with full comprehension of the risks involved, for diagnostic or investigative procedures, and for medical and surgical treatment.Genetic Privacy: The protection of genetic information about an individual, family, or population group, from unauthorized disclosure.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Health Insurance Portability and Accountability Act: Public Law 104-91 enacted in 1996, was designed to improve the efficiency and effectiveness of the healthcare system, protect health insurance coverage for workers and their families, and to protect individual personal health information.Coronary Artery Disease: Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.Plaque, Atherosclerotic: Lesions formed within the walls of ARTERIES.Positron-Emission Tomography: An imaging technique using compounds labelled with short-lived positron-emitting radionuclides (such as carbon-11, nitrogen-13, oxygen-15 and fluorine-18) to measure cell metabolism. It has been useful in study of soft tissues such as CANCER; CARDIOVASCULAR SYSTEM; and brain. SINGLE-PHOTON EMISSION-COMPUTED TOMOGRAPHY is closely related to positron emission tomography, but uses isotopes with longer half-lives and resolution is lower.Tomography, Emission-Computed: Tomography using radioactive emissions from injected RADIONUCLIDES and computer ALGORITHMS to reconstruct an image.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.Mortuary Practice: Activities associated with the disposition of the dead. It excludes cultural practices such as funeral rites.Funeral SermonsPrimary Prevention: Specific practices for the prevention of disease or mental disorders in susceptible individuals or populations. These include HEALTH PROMOTION, including mental health; protective procedures, such as COMMUNICABLE DISEASE CONTROL; and monitoring and regulation of ENVIRONMENTAL POLLUTANTS. Primary prevention is to be distinguished from SECONDARY PREVENTION and TERTIARY PREVENTION.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Practice Guidelines as Topic: Directions or principles presenting current or future rules of policy for assisting health care practitioners in patient care decisions regarding diagnosis, therapy, or related clinical circumstances. The guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by the convening of expert panels. The guidelines form a basis for the evaluation of all aspects of health care and delivery.Coronary Artery Bypass: Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.Fractional Flow Reserve, Myocardial: The ratio of maximum blood flow to the MYOCARDIUM with CORONARY STENOSIS present, to the maximum equivalent blood flow without stenosis. The measurement is commonly used to verify borderline stenosis of CORONARY ARTERIES.Percutaneous Coronary Intervention: A family of percutaneous techniques that are used to manage CORONARY OCCLUSION, including standard balloon angioplasty (PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY), the placement of intracoronary STENTS, and atheroablative technologies (e.g., ATHERECTOMY; ENDARTERECTOMY; THROMBECTOMY; PERCUTANEOUS TRANSLUMINAL LASER ANGIOPLASTY). PTCA was the dominant form of PCI, before the widespread use of stenting.Angioplasty, Balloon, Coronary: Dilation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply.Atlases as Topic: Collections of illustrative plates, charts, etc., usually with explanatory captions.Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).Faculty, Medical: The teaching staff and members of the administrative staff having academic rank in a medical school.Journal Impact Factor: A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.British Columbia: A province of Canada on the Pacific coast. Its capital is Victoria. The name given in 1858 derives from the Columbia River which was named by the American captain Robert Gray for his ship Columbia which in turn was named for Columbus. (From Webster's New Geographical Dictionary, 1988, p178 & Room, Brewer's Dictionary of Names, 1992, p81-2)Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Bibliometrics: The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)Fellowships and Scholarships: Stipends or grants-in-aid granted by foundations or institutions to individuals for study.Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.
Myocardial infarction diagnosis
Anderson, J. L.; Adams, C. D.; Antman, E. M.; Bridges, C. R.; Califf, R. M.; Casey, D. E.; Chavey, W. E.; Fesmire, F. M.; ... The primary purpose of the electrocardiogram is to detect ischemia or acute coronary injury in broad, symptomatic emergency ... Myocardial infarction management Myocardial infarction complications Mallinson, T (2010). "Myocardial Infarction". Focus on ... Myocardial infarction: diagnosis and investigations - GPnotebook, retrieved November 27, 2006. DE Fenton et al. Myocardial ...
The maximum tolerated dose was observed to be an infusion of 0.5 mg/kg/h. Adverse effects, such as ischemia, were only seen at ... Systolic heart failure involves a loss of effective actin-myosin cross bridges in the myocytes (heart muscle cells) of the left ... This causes a decrease in heart rate while myocardial oxygen consumption is unaffected. The increased cardiac output is ... Cardiac myocytes contract through a cross-bridge cycle between the myofilaments, actin and myosin. Chemical energy in the form ...
Hollander, Judd (December 28, 2011). "Update on Cocaine Myocardial Ischemia". Casartelli, Alessandro; Dacome, Lisa; Tessari, ... Anderson, Jeffrey L.; Adams, Cynthia D.; Antman, Elliott M.; Bridges, Charles R.; Califf, Robert M.; Casey, Donald E.; Chavey, ... and myocardial contractility, which are major determinants of myocardial oxygen demand. Cocaine and its metabolites may cause ... This can lead to death from acute myocardial infarction, respiratory failure, stroke, cerebral hemorrhage, or heart failure. ...
Myocardial bridge. Active ischemia. *Angina pectoris *Prinzmetal's angina. *Stable angina. *Acute coronary syndrome *Myocardial ... Secondary AF - occurs in the setting of a primary condition that may be the cause of the AF, such as acute myocardial ... ischemia)). Other possible symptoms include congestive heart failure symptoms such as fatigue, shortness of breath, or swelling ... or other underlying conditions such as chronic lung disease or coronary ischemia. An exercise stress test will evaluate the ...
Premature junctional contraction
ICD-10 Chapter IX: Diseases of the circulatory system
Myocardial bridge. Active ischemia. *Angina pectoris *Prinzmetal's angina. *Stable angina. *Acute coronary syndrome *Myocardial ... I22) Subsequent myocardial infarction. *(I23) Certain current complications following acute myocardial infarction *(I23.0) ... I23.1) Atrial septal defect as current complication following acute myocardial infarction. *(I23.2) Ventricular septal defect ... I23.6) Thrombosis of atrium, auricular appendage, and ventricle as current complications following acute myocardial infarction ...
Left posterior fascicular block
Coronary artery disease
"Percutaneous coronary intervention outcomes in patients with stable obstructive coronary artery disease and myocardial ischemia ... The heart's muscle cells may die from lack of oxygen and this is called a myocardial infarction (commonly referred to as a ... Limitation of blood flow to the heart causes ischemia (cell starvation secondary to a lack of oxygen) of the heart's muscle ... A region on chromosome 17 was confined to families with multiple cases of myocardial infarction. Other genome-wide studies ...
Multifocal atrial tachycardia
Myocardial bridge. Active ischemia. *Angina pectoris *Prinzmetal's angina. *Stable angina. *Acute coronary syndrome *Myocardial ... Myocardial inflammation can be suspected on the basis of electrocardiographic (ECG) results, elevated C-reactive protein (CRP) ... Markers of myocardial damage (troponin or creatine kinase cardiac isoenzymes) are elevated. ... People who do not respond to conventional therapy may be candidates for bridge therapy with left ventricular assist devices. ...
Tricuspid valve stenosis
Right ventricular hypertrophy
... but can occur as a result of myocardial ischemia. Class III anti-arrhythmic drugs such as sotalol and amiodarone prolong the QT ... The most common cause of monomorphic ventricular tachycardia is scarring of the heart muscle from a previous myocardial ... Myocardial bridge. Active ischemia. *Angina pectoris *Prinzmetal's angina. *Stable angina. *Acute coronary syndrome *Myocardial ... if the individual has a past history of a myocardial infarction, congestive heart failure, or recent angina, the wide complex ...
The most common mechanism of damage is ischemia causing infarction and scar formation. After myocardial infarction, dead ... VADs have commonly been used as a bridge to heart transplantation, but have been used more recently as a destination treatment ... Echocardiography can also help determine if acute myocardial ischemia is the precipitating cause, and may manifest as regional ... If myocardial infarction is suspected, various cardiac markers may be used.. According to a meta-analysis comparing BNP and N- ...
हृदयवाहिका रोग - विकिपीडिया
Active ischemia. Angina pectoris (Prinzmetal's angina, Stable angina) · Acute coronary (Unstable angina, Myocardial infarction ... CAD · Coronary thrombosis · Coronary vasospasm · Coronary artery aneurysm · Coronary artery dissection · Myocardial Bridge ... hours (Myocardial stunning, Hibernating myocardium) · days (Myocardial rupture) · weeks (Aneurysm of heart/Ventricular aneurysm ...
Vein graft disease
VGD that progresses to VGF may result in death, myocardial infarction, the need for repeat revascularization and/or lower limb ... post-harvest ischemia, oxidative stress, reperfusion injury and adaptive stress in the new post grafting environment. ... reconstructive surgery in situations where recipient vessels are damaged or are otherwise inadequate and require bridging vein ... myocardial infarction, revascularization, and worsening of symptoms such as angina".(15) Vein Graft Failure following ...
It is now known that hydrogen sulfide has cardioprotective effects in cases of ischemia related to its effects as an endogenous ... Reduction of platelet aggregation may result in reduction of myocardial infarction or ischemic stroke. ... http://www.osti.gov/bridge/product.biblio.jsp?osti_id=867345. ...
Heart failure with preserved ejection fraction
Ischemia can result in impaired relaxation of the heart; when myocytes fail to relax appropriately, myosin cross bridges remain ... reduced myocardial oxygen demand and lowered blood pressure. However, this effect also can contribute to diminished response to ... Ischemia Ischemia, or inadequate oxygenation of the myocardium, is observed in a high proportion of HFpEF patients. This ... Ischemia may manifest in distinct ways, either as a result of increasing tissue oxygen demand, or diminished ability of the ...
හෘද රෝග - විකිපීඩියා, නිදහස් විශ්වකෝෂය
23(51-56). Lee, J.H., et al., Cyclobuxine protects the isolated rat heart from the myocardial injuries produced by ischemia and ... presumably involving a bridged structure using both amino groups. Destabilization is caused by a weaker interaction with sites ... Cyclobuxine was in this way able to suppress the damage (myocardial injury) produced by ischemia. As indicated above, research ... cyclobuxine was also found to have a protective effect on myocardial cells against ischemia and reperfusion (in an isolated rat ...
Vein graft failure
"2014 ESC/EACTS Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European ... Hillis, L. D.; Smith, P. K.; Anderson, J. L.; Bittl, J. A.; Bridges, C. R.; Byrne, J. G.; Cigarroa, J. E.; DiSesa, V. J.; ... VGF may be identified in asymptomatic patients, but can also produce symptoms of ischemia, depending on the area of the ... During and after the harvesting, veins go through a period of ischemia and reperfusion after engraftment, which causes damage ...
MRL mice are not protected against myocardial infarction; heart regeneration in adult mammals (neocardiogenesis) is limited, ... "MRL mice fail to heal the heart in response to ischemia-reperfusion injury". Wound Repair and Regeneration. 13 (2): 205-8. doi: ... "Bridging the regeneration gap: genetic insights from diverse animal models" (PDF). Nature Reviews. Genetics. 7 (11): 873-84. ... "Evidence that human cardiac myocytes divide after myocardial infarction". The New England Journal of Medicine. 344 (23): 1750-7 ...
University of Ottawa Heart Institute
Ontario's first angioplasty The first use in Canada, and 11th in the world, of the Jarvik 7 artificial heart as a bridge to ... The ST-Elevation Myocardial Infarction (STEMI) Protocol, developed at UOHI, specifies that paramedic in Ottawa identify ... recruitment and therapeutic effects of circulating progenitor cells in a hindlimb ischemia model". The FASEB Journal. 23 (5): ... January 2008). "A citywide protocol for primary PCI in ST-segment elevation myocardial infarction". The New England Journal of ...
The suffix -pontin is derived from "pons," the Latin word for bridge, and signifies osteopontin's role as a linking protein. ... Singh M, Dalal S, Singh K (2014). "Osteopontin: At the cross-roads of myocyte survival and myocardial function". Life Sci. 118 ... ischemia, and immune responses1. Therefore, manipulation of plasma (or local) OPN levels may be useful in the treatment of ... Murry CE, Giachelli CM, Schwartz SM, Vracko R (December 1994). "Macrophages express osteopontin during repair of myocardial ...
Systolic coronary occlusion due to myocardial bridging - a rare cause of ischaemia<...
Systolic coronary occlusion due to myocardial bridging - a rare cause of ischaemia. / Furniss, Stephen S.; Williams, David O.; ... Systolic coronary occlusion due to myocardial bridging - a rare cause of ischaemia. International Journal of Cardiology. 1990 ... title = "Systolic coronary occlusion due to myocardial bridging - a rare cause of ischaemia", ... T1 - Systolic coronary occlusion due to myocardial bridging - a rare cause of ischaemia ...
Myocardial Perfusion SPECT: Background, Indications, Contraindications
Impact of acute propranolol administration on dobutamine-induced myocardial ischemia as evaluated by myocardial perfusion ... Dipyridamole TI-201 SPECT imaging in patients with myocardial bridging. Clin Nucl Med. 1999 Oct. 24(10):759-64. [Medline]. ... encoded search term (Myocardial Perfusion SPECT) and Myocardial Perfusion SPECT What to Read Next on Medscape. Related ... Fukuda T, Akagi T, Ishibashi M, Inoue O, Sugimura T, Kato H. Noninvasive evaluation of myocardial ischemia in Kawasaki disease ...
Fire Fighter Fatality Investigation Report F2005-18 | NIOSH | CDC
... "acute myocardial ischemia secondary to a cardiac arrhythmia of unknown etiology." Myocardial bridging (MB) and findings ... Furniss SS, Williams DO and McGregor CG . Systolic coronary occlusion due to myocardial bridging-a rare cause of ischemia ... Vasan RS, Bahl VK, and Rajani M . Myocardial infarction associated with a myocardial bridge. Int J Cardiol 25:240-241. ... van Brussel BL, van Tellingen C, Ernst MP, and Plokker HW . Myocardial bridging: A cause of myocardial infarction? Int J ...
Fire Fighter Fatality Investigation Report F2012-22 | NIOSH | CDC
Furniss SS, Williams DO, McGregor CG . Systolic coronary occlusion due to myocardial bridging-a rare cause of ischemia. ... Myocardial Bridging. Myocardial bridging occurs when a portion of a coronary artery tunnels into the myocardium, creating a ... van Brussel BL, van Tellingen C, Ernst MP, Plokker HW . Myocardial bridging: a cause of myocardial infarction? Int J ... Erbel R, Ge J, Mohlenkamp S . Myocardial bridging: a congenital variant as an anatomic risk factor for myocardial ...
Husmann L[au] - PubMed - NCBI
Myocardial bridging causing infarction and ischaemia.. Husmann L, Nkoulou R, Wolfrum M, Kaufmann PA. ... New reconstruction algorithm allows shortened acquisition time for myocardial perfusion SPECT.. Valenta I, Treyer V, Husmann L ... Myocardial perfusion imaging with real-time respiratory triggering: impact of inspiration breath-hold on left ventricular ... Ultrafast nuclear myocardial perfusion imaging on a new gamma camera with semiconductor detector technique: first clinical ...
Coronary CT Angiography: Practice Essentials, Overview, Clinical Applications: Coronary Artery Disease
Although it is usually a benign anomaly, it has been associated with myocardial ischemia. Myocardial bridging is well ... Myocardial bridging: Maximum intensity projection (MIP) image demonstrates a myocardial bridge (arrow) involving the mid-left ... Myocardial bridging: Maximum intensity projection (MIP) image demonstrates a myocardial bridge (arrow) involving the mid-left ... Myocardial bridging,  also called tunneled artery, is a congenital anomaly where myocardium encases a segment of coronary ...
... and postoperative evaluation of myocardial ischemia in a patient with myocardial bridging: A case report. Lim, Jae Woong; Lee, ... Electrocardiogram in patients with acute inferior myocardial infarction due to occlusion of circumflex artery. Li, Qun; Wang, ... Identifying key genes associated with acute myocardial infarction. Cheng, Ming; An, Shoukuan; Li, Junquan ...
Myocardial bridging: evaluation using single- and dual-source multidetector cardiac computed tomographic angiography. -...
The average myocardial bridge length was 23.4 mm, and the average tunneled artery depth was 2.6 mm. CONCLUSIONS Myocardial ... RESULTS The prevalence of myocardial bridges was 10.4%, most of which were located in the mid-left anterior descending coronary ... METHODS Retrospective review of the imaging characteristics of 57 myocardial bridges in 53 patients who underwent cardiac MDCTA ... bridges are commonly found in patients who undergo cardiac multidetector computed tomographic angiograms on both single- and ...
Evaluation of Persistent or Recurrent Angina Following PCI
Myocardial bridge. Disclosure at coronary angiography of a systolic narrowing, or milking of the vessel, with a step-down ... determining myocardial ischaemia as documented by reduced FFR (≤0.80).. ... FFR with dobutamine challenge is a more appropriate approach for testing the haemodynamic significance of myocardial bridges.. ... Increase in the index of microvascular resistance (,25) or the hyperaemic myocardial resistance (,2.5 mmHg/cm/s). ...
Professor Gemma Figtree - The University of Sydney
PHOSPHOLEMMAN: A CARDIAC MEMBRANE PROTEIN WITH CAPACITY TO REDUCE MYOCARDIAL ISCHAEMIA REPERFUSION INJURY; Figtree G; Sylvia ... FXYDI and effects on ischaemia reperfusion injury; Figtree G; DVC Research/Bridging Support Grant. ... Prodrug Development of Biased N-Alkylpyridazinones for the Acute Intravenous Treatment of Myocardial Ischaemia-Reperfusion ... Automated Quantification of Myocardial Salvage in a Rat Model of Ischemia-Reperfusion Injury Using 3D High-Resolution Magnetic ...
18F-fluoride positron emission tomography for identification of ruptured and high-risk coronary atherosclerotic plaques: a...
24826309 - Nitroglycerine induced acute myocardial infarction in a patient with myocardial bridging.. 19573939 - Nicorandil ... ameliorates impulse conduction disturbances during ischemia in isolated arte.... Publication Detail: Type: Clinical Trial; ... Myocardial Infarction / metabolism. Plaque, Atherosclerotic / diagnosis, metabolism*. Positron-Emission Tomography* / methods. ... FINDINGS: In 37 (93%) patients with myocardial infarction, the highest coronary (18)F-NaF uptake was seen in the culprit plaque ...
Exercise sub-cluster 88
Surgical Repair of 115 Patients With Anomalous Aortic Origin of a Coronary Artery From a Single Institution
Anomalous aortic origin of a coronary artery (AAOCA) has been associated with myocardial ischemia and sudden death. There are ... For the first time, an association between AAOCA and myocardial bridges is reported. ... results demonstrate that AAOCA surgery can be performed safely and is effective in relieving symptoms of myocardial ischemia. ...
What is going on with me - Cardiovascular Disease Prevention - MedHelp
Myocardial bridging of the coronary arteries | Radiology Reference Article | Radiopaedia.org
Myocardial bridging is a common congenital anomaly of the coronary arteries where a coronary artery courses through the ... However, deeper bridging (,2 mm) may cause symptoms of angina or ischemia in some patients. ... Myocardial bridging as evaluated by 16 row MDCT. Eur J Radiol. 2009;69 (1): 156-64. doi:10.1016/j.ejrad.2007.09.038 - Pubmed ... Myocardial bridging is a common congenital anomaly of the coronary arteries where a coronary artery courses through the ...
Natural Antibodies Bridge Innate and Adaptive Immunity | The Journal of Immunology
Natural IgM is also involved in ischemia-reperfusion injury, including myocardial infarction and intestinal ischemia- ... Natural Antibodies Bridge Innate and Adaptive Immunity Message Subject (Your Name) has forwarded a page to you from The Journal ... Natural IgG bridges innate and adaptive immunity and boosts immune response. *Implications of natural Abs in autoimmunity and ... Natural IgG bridges innate and adaptive immunity and boosts immune response. The mechanisms underlying the ligand specificity, ...
Catestatin: A Master Regulator of Cardiovascular Functions | Bentham Science
Bridging Innate Immunity and Myocardial Ischemia/Reperfusion Injury: The Search for Therapeutic Targets. Current Pharmaceutical ... Targeting Transient Receptor Potential Channels in Cardiometabolic Diseases and Myocardial Ischemia Reperfusion Injury. Current ... Mst1: Function and Mechanism in Brain and Myocardial Ischemia Reperfusion Injury. Current Neuropharmacology ... LncRNA MALAT1 is Neuroprotective in a Rat Model of Spinal Cord Ischemia-Reperfusion Injury Through miR-204 Regulation. Current ...
Atlas of FFR-Guided Percutaneous Coronary Interventions | Ebook | Ellibs Ebookstore
Using FFR to Detect Ischemia in Myocardial Bridge Lesions. Tommaso Gori, Massimo Fineschi. 30. ACS-NSTEMI. Massimo Fineschi. 31 ... Using FFR to Detect Ischemia in Myocardial Bridge Lesions. Tommaso Gori, Massimo Fineschi. 30. ACS-NSTEMI. Massimo Fineschi. 31 ... FFR Provides Indication on Myocardial Viability. Massimo Fineschi. 39. FFR in a Bypass. Tommaso Gori. 40. Heart Failure: Really ... FFR Provides Indication on Myocardial Viability. Massimo Fineschi. 39. FFR in a Bypass. Tommaso Gori. 40. Heart Failure: Really ...
Associate Professor Paul Witting - The University of Sydney
Neuzil, J., Rayner, B., Lowe, H., Witting, P. (2005). Oxidative stress in myocardial ischaemia reperfusion injury: a renewed ... Cellular response to pro-oxidative myoglobin - relinquished; Witting P; DVC Research/Bridging Support Fellowship. ... Neuzil, J., Rayner, B., Lowe, H., Witting, P. (2005). Oxidative stress in myocardial ischaemia reperfusion injury: a renewed ... Role for Myoglobin in myocardial ischemia reperfusion injury.; Witting P; National Heart Foundation/Scholarship. ...
Coronary artery bypass surgery perioperative management of myocardial ischemia - wikidoc
Hillis LD, Smith PK, Anderson JL, Bittl JA, Bridges CR, Byrne JG; et al. (2011). "2011 ACCF/AHA Guideline for Coronary Artery ... Coronary artery bypass surgery perioperative management of myocardial ischemia. Revision as of 14:36, 2 October 2012 by Esther ... Directions to Hospitals Performing Coronary artery bypass surgery perioperative management of myocardial ischemia ... Coronary artery bypass surgery perioperative management of myocardial ischemia in the news ...
Ingela Schnittger, MD | Stanford Medicine Profiles
Although it is general perception that myocardial bridges are normal variants, patients with myocardial bridges can present ... ULTRASONIC TISSUE CHARACTERIZATION - DETECTION OF ACUTE MYOCARDIAL ISCHEMIA IN DOGS CIRCULATION Schnittger, I., Vieli, A., ... Myocardial bridging. Journal of the American College of Cardiology Tremmel, J. A., Schnittger, I. 2014; 64 (20): 2178-2179 View ... Myocardial Bridge and Acute Plaque Rupture. Journal of investigative medicine high impact case reports Perl, L., Daniels, D., ...
Ian S. Rogers, M.D., M.P.H. | Stanford Medicine Profiles
Although it is general perception that myocardial bridges are normal variants, patients with myocardial bridges can present ... Anomalous aortic origin of a coronary artery (AAOCA) has been associated with myocardial ischemia and sudden death. The past ... Myocardial bridges: Overview of diagnosis and management. Congenital heart disease Rogers, I. S., Tremmel, J. A., Schnittger, I ... A myocardial bridge is a segment of a coronary artery that travels into the myocardium instead of the normal epicardial course ...
Myocardial infarction - Factbites
Myocardial bridging usually has a benign prognosis, but some cases associated with myocardial ischemia, infarction, and sudden ... Acute Myocardial Infarction. Myocardial infarction occurs when myocardial ischemia exceeds a critical threshold and overwhelms ... This is a case of acute myocardial infarction caused by coronary thrombosis in the setting of myocardial bridging. ... eMedicine - Myocardial Infarction : Article by Drew E Fenton. Myocardial infarction (MI) is the rapid development of myocardial ...
Abstract 1712: Deep Myocardial Bridging is a Risk Factor for Sudden Death in Hypertrophic Cardiomyopathy | Circulation
Myocardial bridging (MB) of the left anterior descending (LAD) coronary artery segment has been linked with myocardial ischemia ... Abstract 1712: Deep Myocardial Bridging is a Risk Factor for Sudden Death in Hypertrophic Cardiomyopathy. Cristina Basso, Barry ... Abstract 1712: Deep Myocardial Bridging is a Risk Factor for Sudden Death in Hypertrophic Cardiomyopathy ... Abstract 1712: Deep Myocardial Bridging is a Risk Factor for Sudden Death in Hypertrophic Cardiomyopathy ...
Noninvasive Imaging for Suspected CAD: Which Test When?
... myocardial bridging or the detection of congenital coronary arterial abnormalities).. Another controversial area is viability ... Once the diagnostic goal has been established, most imaging in ACS takes place after ischemia has been eliminated. It is ... The major diagnoses in the acute setting beyond myocardial infarction include stress cardiomyopathy, myocarditis and/or ... or nuclear cardiac imaging if I am considering an assessment of myocardial viability in a patient with established CAD with ...
New P2Y12 Inhibitors | Circulation
... myocardial infarction, and ischemia-driven revascularization. Both studies were terminated prematurely because of insufficient ... However, it is still being studied as a bridge for patients who need to suspend treatment with thienopyridines to undergo ... After 12 months of follow-up, the primary end point (a composite of vascular death, myocardial infarction, or stroke) had ... Cangrelor is still being studied as a bridge for patients who need to suspend treatment with thienopyridines before undergoing ...
Neuraxial analgesia for labor & delivery - Renal and Urology News
Neuraxial analgesia for labor is beneficial in patients with myocardial ischemia or reduced ejection fraction because it ... Cardiac medications including digoxin, dobutamine, and milrinone can be used when needed as a bridge to delivery and further ... Preexisting myocardial insufficiency is concerning, particularly when it is due to peripartum cardiomyopathy which can recur or ... ST-segment depression may occur and is usually not related to chest pain or apparent cardiac ischemia. ...
PPT - What is Cardiology Clearance? PowerPoint Presentation - ID:348168
InfarctionLeftInfarctionReperfusionSuddenPrevalenceRegional myocardialAnginaBenignInducibleAbstractMorphological and functional aspectsUnderwentSystolic compressionComplicationsHemodynamicArtery diseaseOxygenSegmentCase of myocardial2002Presence of ischemiaLeft ventricleCongenitalSevere ischemiaNecrosisCompressionSymptomsMultidetector computed tAssessmentDysfunctionEchocardiographyObstructiveOccursInnate and adaptiveFibrosisFINDINGSPulmonary
- Further increases in myocardial oxygen consumption ensue in infarction of the anterolateral left ventricular free wall, often with resultant mitral valve insufficiency. (radiopaedia.org)
- Death is usually due to circulatory insufficiency from left ventricular dysfunction or mitral valve incompetence , myocardial infarction , or life-threatening cardiac dysrhythmias 3 . (radiopaedia.org)
- METHODS: In this prospective clinical trial, patients with myocardial infarction (n=40) and stable angina (n=40) underwent (18)F-NaF and (18)F-FDG PET-CT, and invasive coronary angiography. (biomedsearch.com)
- The primary endpoint was the comparison of (18)F-fluoride tissue-to-background ratios of culprit and non-culprit coronary plaques of patients with acute myocardial infarction. (biomedsearch.com)
- The traditional concept that myocardial infarctions can be classified as transmural or nontransmural on the basis of the presence or absence of Q waves is misleading, since autopsy studies have demonstrated convincingly that pathologic Q waves may be associated with nontransmural infarction and may be absent with transmural infarction . (factbites.com)
- Reference:Montalescot,G. and others,Platelet glycoprotein IIb/IIIa inhibition with coronary stenting for acute myocardial infarction,N.Engl.J.Med. (factbites.com)
- Myocardial infarction occurs when myocardial ischemia exceeds a critical threshold and overwhelms myocardial cellular repair mechanisms that are designed to maintain normal operating function and hemostasis. (factbites.com)
- Myocardial infarction is the leading cause of death in the United States (US) as well as in most industrialized nations throughout the world. (factbites.com)
- A heart attack or myocardial infarction is a medical emergency in which the supply of blood to the heart is suddenly and severely reduced or cut off, causing the muscle to die from lack of oxygen . (factbites.com)
- More than 1.1 million people experience a heart attack ( myocardial infarction ) each year, and for many of them, the heart attack is their first symptom of coronary artery disease . (factbites.com)
- A heart attack ( myocardial infarction ) is usually caused by a blood clot that blocks an artery of the heart . (factbites.com)
- Myocardial bridging usually has a benign prognosis, but some cases associated with myocardial ischemia , infarction , and sudden death have been reported [1- (factbites.com)
- This is a case of acute myocardial infarction caused by coronary thrombosis in the setting of myocardial bridging. (factbites.com)
- Acute myocardial infarction with rupture and tamponade, gross. (factbites.com)
- Cardiac troponin I in the diagnosis of myocardial injury and infarction . (factbites.com)
- Myocardial infarction (MI) is the rapid development of myocardial necrosis caused by a critical imbalance between oxygen supply and demand of the myocardium . (factbites.com)
- The major diagnoses in the acute setting beyond myocardial infarction include stress cardiomyopathy, myocarditis and/or pericarditis, pulmonary embolism, and the acute aortic syndromes. (medscape.com)
- It is often considered a benign normal variant of coronary anatomy, but it has been rarely linked to myocardial ischemia, infarction, and sudden cardiac death. (lww.com)
- Inotropes and/or vasopressors are essential in the management of cardiogenic shock complicating myocardial infarction/ischemia and in the treatment of hemodynamic instability occurring during coronary interventions. (renalandurologynews.com)
- In this regard, myocardial bridging is usually considered a normal variant with no hemodynamic relevance, but it has been associated also with relevant clinical complications, such as myocardial ischemia and myocardial infarction ( 9-13 ). (onlinejacc.org)
- Several studies have documented that transplantation of bone marrow-derived cells (BMC) following acute myocardial infarction is associated with a reduction in infarct scar size and improvements in left ventricular function and perfusion. (stanford.edu)
- The available evidence in humans suggests that BMC transplantation is associated with improvements in physiologic and anatomic parameters in both acute myocardial infarction and chronic ischemic heart disease, above and beyond the conventional therapy. (stanford.edu)
- Rg1 prevented I/R-elicited insults in myocardium, including myocardial infarction and apoptosis, decreased myocardial blood flow (MBF) and heart function, and alteration in myocardium structure. (frontiersin.org)
- MVS via Impella is applied in several cardiogenic shock etiologies, such as acute myocardial infarction (support over days) or acute fulminant myocarditis (prolonged support over weeks, PROPELLA). (frontiersin.org)
- Described herein is a 42-year-old woman who suddenly developed a spontaneous isolated coronary arterial dissection which led to massive acute myocardial infarction with shock, unsuccessful coronary artery bypass grafting, transiently successful extracorporeal life support, and finally successful heart transplant. (medworm.com)
- Coronary collateralisation, occurring particularly in the presence of coronary artery disease (CAD), is considered protective in the case of myocardial infarction. (bmj.com)
- Known markers for acute myocardial infarction (AMI) including creatine kinase (CK) activity, C-reactive protein (CRP) level and blood cell counts are thought to be altered in other pathological conditions such as infections. (conferenceseries.net)
- Patient delay is a worldwide unsolved problem in ST-segment elevated myocardial infarction (STEMI). (bvsalud.org)
- Moreover, DXS is very effective in protecting vasculature and tissue from ischemia/reperfusion injury, as recently shown in a porcine model of acute myocardial infarction ( 6 ). (jimmunol.org)
- Ischaemic heart disease refers to a group of clinico-pathological symptoms including angina pectoris, acute myocardial infarction, chronic ischemic heart disease, as well as heart failure and sudden cardiac death. (springer.com)
- Coronary artery thrombosis is the most common cause of acute myocardial infarction and sudden cardiac death. (springer.com)
- Fourth universal definition of myocardial infarction. (springer.com)
- Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. (springer.com)
- Thiene G, Basso C. Myocardial infarction: a paradigm of success in modern medicine. (springer.com)
- Angiographic progression of coronary artery disease and the development of myocardial infarction. (springer.com)
- Relationship between extent of residual myocardial viability and coronary flow reserve in patients with recent myocardial infarction. (thefreedictionary.com)
- Although MB is considered to be a benign condition with a good long-term prognosis, there are a few reports linking MB to acute myocardial infarction, arrhythmias, or sudden death. (massgeneral.org)
- Mechanisms of atherothrombosis and vascular response to primary percutaneous coronary intervention in women versus men with acute myocardial infarction: results of the OCTAVIA study. (cvpath.org)
- Myocardial infarction (MI) is a complication that can occur after endoscopic submucosal dissection (ESD). (bvsalud.org)
- As indicated by their clinical presentation, it is anticipated that all patients in this study will have an electrocardiogram (ECG) upon admission to the ED and if the patient is found not to have an ST-elevation myocardial infarction (STEMI), objective cardiac testing will be conducted for evidence of MI. (bioportfolio.com)
- 1 Stunning is known to occur after exercise-induced ischemia, 2 coronary angioplasty, 3 and cardiopulmonary bypass 4 and in patients with unstable angina 5 and, to varying degrees, in patients with myocardial infarction after reperfusion. (ahajournals.org)
- This study evaluates the association between microvascular obstruction and myocardial salvage, determined by cardiac magnetic resonance performed both in the acute stage of myocardial infarction and after 4 months. (jove.com)
- This architectural remodelling of the left ventricle is induced by injury ( e.g., myocardial infarction), by pressure overload ( e.g., systemic arterial hypertension or aortic stenosis), or by volume overload. (jove.com)
- A model of permanent ligation of the left anterior descending coronary artery in mice is used to investigate ventricular remodelling and cardiac function post-myocardial infarction. (jove.com)
- One important prerequisite is a good understanding of all safety and efficacy aspects obtained in a large animal model that validly reflect the human scenario of myocardial infarction (MI). (jove.com)
- In this report, we present a case of cardiogenic shock that mimics ST-elevation myocardial infarction, due to dynamic left ventricular outflow tract obstruction with transient mitral regurgitation and myocardial bridging after transient complete atrioventricular block. (beds.ac.uk)
- The patient presented with a case of cardiogenic shock that mimicked ST-elevation myocardial infarction due to dynamic left ventricular outflow tract obstruction combined with myocardial bridging in the mid-left anterior descending artery. (beds.ac.uk)
- however some cases have been reported of unstable perfusion of the coronary arteries that caused serious cardiac disorders such as myocardial ischemia, myocardial infarction, arrhythmia and even sudden cardiac death. (beds.ac.uk)
- In this report, a case is presented of cardiogenic shock that mimicked ST-elevation myocardial infarction (STEMI) due to dynamic LVOT obstruction combined with myocardial bridging in the mid-left anterior descending artery (LAD) after transient complete atrioventricular block (AV block). (beds.ac.uk)
- Increasing coronary atherosclerosis can lead to obstructive coronary artery disease (CAD) or myocardial infarction. (utupub.fi)
- The broader strokes of his research focus on the development of the next generation ultrasound enhancing agent that is engineered for quantifying myocardial perfusion, monitoring ischemia, and detecting infarction. (drexel.edu)
- A diagnosis of myocardial infarction is created by integrating the history of the presenting illness and physical examination with electrocardiogram findings and cardiac markers (blood tests for heart muscle cell damage). (wikipedia.org)
- At autopsy, a pathologist can diagnose a myocardial infarction based on anatomopathological findings. (wikipedia.org)
- New regional wall motion abnormalities on an echocardiogram are also suggestive of a myocardial infarction. (wikipedia.org)
- In particular, acute myocardial infarction in the distribution of the circumflex artery is likely to produce a nondiagnostic ECG. (wikipedia.org)
- The use of additional ECG leads like right-sided leads V3R and V4R and posterior leads V7, V8, and V9 may improve sensitivity for right ventricular and posterior myocardial infarction. (wikipedia.org)
- A normal ECG does not rule out acute myocardial infarction. (wikipedia.org)
- It should be determined if a person is at high risk for myocardial infarction before conducting imaging tests to make a diagnosis. (wikipedia.org)
- Occlusion of one or more of these blood vessels ( coronary occlusion ) is one of the major causes of myocardial infarction. (thefreedictionary.com)
- The most common sites of myocardial infarction are in the left ventricle, that chamber of the heart which has the greatest workload. (thefreedictionary.com)
- The most outstanding symptom of acute myocardial infarction is a sudden painful sensation of pressure, often described as a "crushing pain" in the chest, occasionally radiating to the arms, throat, and back, and persisting for hours. (thefreedictionary.com)
- An amazing quantity of information suggest how the inhibition involving MPO is probably useful in CV pathologies seen as increased MPO ranges (myocardial swelling, ischemia-reperfusion injury as well as serious MI). (dailystrength.org)
- We thus speculated that the protective effect of Rg1 on heart ischemia and reperfusion (I/R) injury implicates energy metabolism regulation. (frontiersin.org)
- Myocradial blood flow and heart function were monitored over the period of I/R. Myocardial infarct size, structure and apoptosis, energy metabolism, and change in RhoA signaling pathway were evaluated 90 min after reperfusion. (frontiersin.org)
- Ischemia and reperfusion (I/R) injury is a pathogenesis process consisting of a spectrum of episodes, among which mitochondria dysfunction plays a central role. (frontiersin.org)
- Conclusions RO led to an increased myocardial resistance against ischaemia and reperfusion injury. (bmj.com)
- There are discoveries at the cellular and molecular level about ischemia and reperfusion pathobiology that may be translated into future new therapies. (ahajournals.org)
- In addition to providing protection from microbial infections, the LP has been shown to be involved in inducing post-ischemic inflammatory tissue loss (ischemia/ reperfusion injury), which significantly contributes to the pathology of ischemic diseases such as, myocardial, renal and GI ischemia. (bl.uk)
- Variable degrees and durations of low-flow ischemia were followed by 30 minutes of reperfusion in an open-chest porcine model of regional myocardial stunning (n=27). (ahajournals.org)
- 6 7 Although the etiology of stunning is not fully understood, considerable evidence suggests that the formation of oxygen-derived free radicals and elevated cytosolic Ca 2+ during ischemia and early reperfusion contributes to the development of stunning. (ahajournals.org)
- 14 A subsequent study using the same model showed that Ca 2+ sensitivity of tension is unchanged during ischemia and that the decrease in Ca 2+ sensitivity occurs during reperfusion. (ahajournals.org)
- 15 Taken together, these results demonstrate that Ca 2+ sensitivity of myocardial tension is reduced after reperfusion, and this may account for the depressed contractile function associated with stunning. (ahajournals.org)
- In this latter model of ischemia/reperfusion injury, the initial extent of the infarct may be modulated by factors that affect myocardial salvage following reperfusion. (jove.com)
- RESULTS The prevalence of myocardial bridges was 10.4%, most of which were located in the mid-left anterior descending coronary artery. (semanticscholar.org)
- Prevalence and predictors of bridging of coronary arteries in a large Indonesian population, as detected by 64-slice computed tomography scan. (semanticscholar.org)
- Prevalence of myocardial bridging and correlation with coronary atherosclerosis studied with 64-slice CT coronary angiography. (radiopaedia.org)
- Prevalence during autopsy has been described in multiple studies, varying widely from five to 85 percent, but most studies cite myocardial bridging prevalence between 20 and 55 percent. (lww.com)
- Objectives This study sought to evaluate the prevalence and potential role of myocardial bridging in the pathogenesis of apical ballooning syndrome (ABS). (onlinejacc.org)
- The prevalence of myocardial bridging detected by CTA and CA in ABS patients was compared with 401 controls without ABS who underwent both CTA and CA. (onlinejacc.org)
- Tissue Doppler and strain echocardiography that allow quantitation of regional myocardial mechanics recently have been shown to be accurate in detection of coronary artery disease (CAD) ( 2-4 ). (onlinejacc.org)
- Although many of the techniques used did not actually assess regional myocardial mechanics, they did confirm the presence of regionally heterogeneous relaxation in the presence of ischemia ( 7,8 ). (onlinejacc.org)
- Changes in ventricular depolarisation vectors during exercise caused by regional myocardial ischaemia. (mazenz.com)
- Myocardial bridging causing systolic occlusion of the left anterior descending coronary artery was identified in a 47-year-old man with angina. (umn.edu)
- 2 mm) may cause symptoms of angina or ischemia in some patients. (radiopaedia.org)
- Accuracy of a novel stress echocardiography pattern for myocardial bridging in patients with angina and no obstructive coronary artery disease - A retrospective and prospective cohort study. (stanford.edu)
- with symptoms of Typical Angina, male sex prevailed, and presented a greater association to heart disease and myocardial ischemia. (fac.org.ar)
- 2 In 1809, Allen Burns (Lecturer in Anatomy, University of Glasgow) developed the thesis that myocardial ischaemia (supply:demand mismatch) could explain angina, this being first identified by William Heberden in 1768. (bmj.com)
- 3 Typically, angina involves a relative deficiency of myocardial oxygen supply (ie, ischaemia) and typically occurs after activity or physiological stress ( box 1 ). (bmj.com)
- The most common surgical procedure encountered is the Aorto-Coronary Bypass Graft (ACBG) for various indications such as left main coronary artery stenosis, severe triple-vessel disease, angina refractory to medical therapy, or recurrent CHF due to ischemia. (nazory.cz)
- The diagnostic management of patients with angina pectoris typically centres on the detection of obstructive epicardial CAD, which aligns with evidence-based treatment options that include medical therapy and myocardial revascularisation. (gla.ac.uk)
- This common scenario presents a diagnostic conundrum whereby angina occurs but there is no obstructive CAD (ischaemia and no obstructive coronary artery disease-INOCA). (gla.ac.uk)
- However, there are some studies questioned the capability of CAC to rule out the obstructive CAD, in these studies, higher rates of obstructive noncalcified plaques (6% to 39%) or inducible ischemia (16%), especially in higher risk patients, unstable patients with unstable chest pain, and patients presented to the emergency department [ 9 - 12 ]. (pulsus.com)
Morphological and functional aspects1
- A fixed anterolateral wall defect was demonstrated on thallium imaging and he underwent successful division of the bridge resulting in abolition of his symptoms and disappearance of the thallium defect. (umn.edu)
- This study presents five patients who underwent MSC as bridge therapy for heart transplantation in a developing country. (biomedcentral.com)
- We present five patients who underwent MCS as bridge therapy for heart transplant between 2010 and 2015 at Fundación Cardioinfantil-Instituto de Cardiología. (biomedcentral.com)
- From January of 2010 to December 2015, five patients underwent ECLS or ventricular assist devices as bridge therapy for heart transplantation at Fundación Cardioinfantil-Instituto de Cardiología, Bogotá-Colombia. (biomedcentral.com)
- Ten patients underwent exercise testing and none had hypotension, arrhythmias or ischaemia during exercise. (taiwanscientific.com.tw)
- Five patients underwent catheterisation and none of them had myocardial bridge. (taiwanscientific.com.tw)
- Coronary angiogram demonstrating a mid-LAD myocardial bridge with systolic compression. (massgeneral.org)
- Myocardial bridging (MB) is a congenital variant of CA anatomy in which an arterial segment takes an intramyocardial course, which may result in systolic compression by overlying myocardial tissue. (massgeneral.org)
- They help stabilize patients at risk for progressive hemodynamic collapse or serve as a life-sustaining bridge to a more definitive therapy. (renalandurologynews.com)
- Thus the hemodynamic benefits of inotropes and vasoconstrictors usually outweigh this risk when used as a bridge to more definitive therapies. (renalandurologynews.com)
- On June 27, 2011, a 47-year-old male career artery disease and myocardial bridging of an- fire chief ("the Chief") responded to two medi- terior descending coronary artery" as the cause cal calls. (cdc.gov)
- 5 ESC guidelines 6 have revised nomenclature ('Chronic Coronary Syndromes') in part reflecting the importance of patients with signs and symptoms of ischaemia without obstructive coronary artery disease-INOCA. (bmj.com)
- Myocardial bridging was observed in the mid segment of the left anterior descending coronary artery on coronary angiogram . (factbites.com)
- Myocardial bridging, defined as a band of muscle overlying the intramyocardial segment of an epicardial coronary artery, was initially described in 1737 by Reyman during autopsy. (lww.com)
- The most common location for a myocardial bridge is the middle segment of the left anterior descending coronary artery (LAD). (lww.com)
- All myocardial bridging was located in the mid segment of the left anterior descending coronary artery (LAD) with a mean length of 17 ± 9 mm. (onlinejacc.org)
- The patients with bridging also had greater ST-segment depression with exercise (median, 5 vs. 0 mm, P=0.004) and a shorter duration of exercise (mean, 6.6±2.4 vs. 9.1±1.4 minutes, P=0.008). (elsevier.com)
- Maximum intensity projection (MIP) image demonstrating an LAD myocardial bridge segment measuring at least 45 mm in length running 10 mm deep to the epicardial surface. (massgeneral.org)
- His coronary angiography revealed almost normal right coronary artery and left circumflex artery and only a severe myocardial bridge in the mid-segment of his left anterior descending artery. (beds.ac.uk)
Case of myocardial1
- As a result of this study MB were found at high rate in human, dog, sheep, goat, and it was considered that might be as a risk factor when the MB associated with heart diseases Key Words: Myocardial bridge, Morphology, Species differences T Klin J Med Sci 2002, 22: Çalımamızın amacı insan, köpek, koyun ve keçide myokardiyal köprü (MK) lerin morfolojiik özelliklerinin karılatırmalı olarak incelenmesidir. (biz.tr)
Presence of ischemia1
- J Cardiovasc Dis Res 2012;3:176), which is likely due to most bridges being small and causing minimal compression. (lww.com)
- The traditional concept is that the ischemia sustains in the 'Milking effect', that is, outer vascular compression of the coronary artery in sistole by the myocardial bridging contraction, reducing the coronary systolic flow. (fac.org.ar)
- Myocardial bridging may cause compression of a coronary artery, and it has been suggested that myocardial ischemia may result. (elsevier.com)
- Myocardial bridging does not produce any symptoms in the majority of patients. (radiopaedia.org)
- The results demonstrate that AAOCA surgery can be performed safely and is effective in relieving symptoms of myocardial ischemia. (ctsnet.org)
- Several occult coronary abnormalities, including endothelial dysfunction, microvascular dysfunction (MVD), and/or a myocardial bridge (MB), may explain their symptoms. (stanford.edu)
Multidetector computed t1
- Myocardial bridging of the left anterior descending coronary artery and anomalous origin of circumflex coronary artery: preoperative assessment with MDCT. (radiopaedia.org)
- Assessment of myocardial ischemia by echocardiography rests on the detection of systolic wall motion abnormalities, namely, reduced wall thickening. (onlinejacc.org)
- Although there has been a focus on assessment of systolic abnormalities, ischemia also affects diastole. (onlinejacc.org)
- The etiology of ABS remains unclear, and ABS may be due to catecholamine-mediated myocardial stunning, coronary spasm, coronary emboli with spontaneous fibrinolysis, or microvascular dysfunction ( 1-5 ). (onlinejacc.org)
- Myocardial stunning is a form of reversible contractile dysfunction that occurs after brief periods of ischemia. (ahajournals.org)
- Thus, there is increasing evidence that ischemia induces regional diastolic mechanical abnormalities that are recognizable using novel imaging techniques such as strain echocardiography, and these altered diastolic patterns could be potentially applied to quantify and improve detection of CAD by echocardiography. (onlinejacc.org)
- 4 The detection of obstructive CAD allows evidence-based medical treatment and consideration of myocardial revascularisation. (bmj.com)
- Macrovascular disease may be due to the presence of obstructive CAD secondary to atherosclerosis, or may be dynamic due to a functional disorder (eg, coronary artery spasm, myocardial bridging). (gla.ac.uk)
Innate and adaptive3
- This review provides new insights into the interaction between natural Abs and lectins, with implications on how interactions between molecules of the innate and adaptive immune systems bridge these two arms of immunity. (jimmunol.org)
- Dendritic cells (DC) are the most potent APC and play an important role in bridging innate and adaptive immunity ( 7 ). (jimmunol.org)
- The complement system bridges the innate and adaptive immune responses. (bl.uk)
- In a rat model of dilated cardiomyopathy, intramyocardial delivery of pluripotent mesenchymal cells improved LVEF, possibly through induction of myogenesis and angiogenesis, as well as by inhibition of myocardial fibrosis, suggesting that the beneficial effects of stem cell transplantation in dilated cardiomyopathy may primarily be related to their ability to supply large amounts of angiogenic, antiapoptotic, and mitogenic factors. (stanford.edu)
- The downstream molecular pathways leading to these heterogeneous phenotypes include changes in acto-myosin cross-bridge kinetics, altered mechanosensation, disturbed calcium sensitivity, de-regulated signalling pathways, inefficient energetics, myocardial ischaemia and fibrosis. (bmj.com)
- It is also possible to detect diffuse myocardial processes such as interstitial fibrosis or edema 1-6 . (jove.com)