Inflammation of the iris characterized by circumcorneal injection, aqueous flare, keratotic precipitates, and constricted and sluggish pupil along with discoloration of the iris.

Confocal microscopy in the iridocorneal endothelial syndrome. (1/48)

AIMS: To report the appearances of iridocorneal endothelial (ICE) syndrome from real time, white light confocal microscopy. METHODS: Three consecutive patients, each with ICE syndrome, were examined prospectively. Corneal specular and confocal microscopic examinations were performed in all three patients. In the first patient, a penetrating keratoplasty was performed and the cornea was examined by light and scanning electron microscopy. No surgery was performed in the remaining two patients. RESULTS: In the first patient corneal oedema prevented endothelial specular microscopy. Confocal microscopy performed before penetrating keratoplasty successfully revealed abnormal epithelial-like endothelial cells. Histological examinations of the cornea following penetrating keratoplasty revealed the presence of multilayered endothelial cells with epithelial features (microvilli). In the remaining two patients, specular microscopy showed the presence of ICE cells with typical dark/light reversal. Confocal microscopy demonstrated groups of endothelial cells with epitheloid appearances. In all three patients, the contralateral endothelial appearance was normal by specular and confocal microscopy, except for moderate endothelial polymegathism in one patient. Epithelial-like endothelial cells were characterised by prominent nuclei on confocal microscopy. CONCLUSIONS: The application of confocal microscopy indicates that the ICE syndrome is characterised by epitheloid changes in the endothelium. Confocal microscopy may be used to diagnose the ICE syndrome by demonstrating epithelial-like endothelial cells with hyperreflective nuclei. This technique is especially of value in cases of corneal oedema, since specular microscopy may fail to image the endothelium in such cases.  (+info)

Effect of local corticosteroids on antibody-forming cells in the eye and draining lymph nodes. (2/48)

Significant numbers of antibody-forming cells (AFC) have been found in the cornea, uveal tract, and draining lymph nodes after the intracorneal injection of bovine gamma-globulin (BGG). To study the effect of locally administered corticosteroids on these antibody-forming tissues, we made unilateral intracorneal injections of rabbit eyes with BGG. These we followed immediately with subconjunctival injections of 10 mg. of triamcinolone suspension, and then with a second round of 10 mg. injections seven days later. A control group of animals received the BGG injections followed by two subconjunctival saline injections. We killed the animals on postinjection days 6, 9, 12, 15, and 21, and tested the draining lymph nodes, homolateral uveal tissue, and homolateral cornea for AFC by a modification of the Jerne placque technique. The local steroids had no effect on the number of AFC produced in the draining lymph nodes or on the circulating antibody response, but they reduced the number of AFC in the homolateral uveal tracts and corneas. Clinically there was less inflammatory response in the steroid-treated eyes than in the control eyes. The possible mechanisms by which corticosteroids achieve their anti-immunologic and anti-inflammatory benefits are discussed.  (+info)

Prolonged prodrome, systemic vasculitis, and deafness in Cogan's syndrome. (3/48)

Cogan's syndrome is a rare, multisystem disease which occurs predominantly in children and young adults. It was originally described as the combination of interstitial keratitis and audiovestibular disturbance, but other forms of ocular disease, as well as systemic vasculitis, have since been recognised as part of the syndrome. Diagnosis can be difficult if the various manifestations occur separately, but early recognition is important because prompt treatment may prevent deafness. Two cases are presented here illustrating the features of this disease, and providing histological evidence of systemic vasculitis in both.  (+info)

Blockage of complement regulators in the conjunctiva and within the eye leads to massive inflammation and iritis. (4/48)

The open environment of the eye is continuously subject to an influx of foreign agents that can activate complement. Decay-accelerating factor (DAF), membrane cofactor protein (MCP) and CD59 are regulators that protect self-cells from autologous complement activation on their surfaces. They are expressed in the eye at unusually high levels but their physiological importance in this site is unstudied. In the rat, a structural analogue termed 5I2 antigen (5I2 Ag) has actions overlapping DAF and MCP. In this investigation, we injected F(ab')2 fragments of 5I2 mAb into the conjunctiva and aqueous humor, in the latter case with and without concomitant blockage of CD59. Massive neutrophilic infiltration of the stroma and iris resulted upon blocking 5I2 Ag activity. Frank necrosis of the iris occurred upon concomitant intraocular blockage of CD59. C3b was identified immunohistochemically, and minimal effects were seen in complement-depleted animals and in those treated with non-relevant antibody. The finding that blockage of 5I2 Ag function in periocular tissues and within the eye causes intense conjunctival inflammation and iritis demonstrates the importance of intrinsic complement regulators in protecting ocular tissues from spontaneous or bystander attack by autologous complement.  (+info)

Increased prevalence of familial autoimmunity in simplex and multiplex families with juvenile rheumatoid arthritis. (5/48)

OBJECTIVE: To determine if the prevalence of autoimmunity among relatives of patients with juvenile rheumatoid arthritis (JRA) is greater than that among relatives of healthy volunteer control subjects. METHODS: Interviews were used to obtain histories of the following disorders among living first- and second-degree relatives of 110 patients and 45 controls: alopecia areata, ankylosing spondylitis, dermatomyositis, Graves' disease, Hashimoto thyroiditis, insulin-dependent diabetes mellitus, inflammatory bowel disease, iritis, JRA, multiple sclerosis, psoriasis, RA, systemic lupus erythematosus, and vitiligo. Chi-squares, odds ratios (ORs), and 95% confidence intervals (95% CIs) were calculated. Families of 23 JRA affected sibpairs were interviewed subsequently. RESULTS: There were no significant differences between patients and controls with regard to age, sex, ethnicity, or family size. Patients had 1,228 relatives and controls had 496 relatives. Of all the relatives of the patients, 155 had at least 1 autoimmune disorder, compared with 20 relatives of the controls (12.6% versus 4.0%; OR 3.4 [95% CI 2.1-5.7], P < 0.000001). The prevalence of autoimmunity was increased in first-degree and in second-degree relatives of patients (16.1% and 10.6%, respectively). The prevalence of Hashimoto thyroiditis was significantly higher in the relatives of patients (OR 3.5 [95% CI 1.6-7.9], P = 0.0008). The prevalences of other disorders were not significantly different. JRA affected sibpair families had an increased prevalence of autoimmunity (15.0%). A history of arthritis was found significantly more frequently in the JRA affected sibpair families, but not in the simplex families. CONCLUSION: These data demonstrate that the prevalence of autoimmunity is significantly higher among first- and second-degree relatives of JRA patients. This suggests that clinically different autoimmune phenotypes may share common susceptibility genes, which may act as risk factors for autoimmunity.  (+info)

An unusual case of late ocular changes after lightning injury. (6/48)

We describe a case of late ocular changes after lightning injury. One year after the injury, complete ankyloblepharon, severe dry eye, corneal opacity, healed iritis and mature cataracts were noted in both eyes of the patient.  (+info)

An ocular model of adenovirus type 5 infection in the NZ rabbit. (7/48)

Ocular adenoviral infections occur worldwide, and currently, there is no ocular animal model for evaluating new antivirals or studying pathogenesis. With a paired-eye design, an ocular model was developed in 32 New Zealand rabbits following topical and intrastromal inoculation with a clinical isolate of adenovirus type 5 (Ad5 McEwen). Clinical signs of infection--conjunctivitis, corneal edema, subepithelial infiltrates, and iritis--and seroconversion were evaluated. Replicating virus on the ocular surface was determined by serial ocular titers. Reproducible acute ocular infection was demonstrated in 32 of 32 infected eyes (100%), with mean viral replication lasting for 8.3 days. Peak ocular viral titers (10(3) plaque forming units/ml) were achieved on day three after inoculation and represented a 2 log increase (100 times) over day one. Ocular viral replication was associated with acute conjunctivitis (24/34 eyes, 75%), and delayed-onset presumed immune-mediated clinical disease was associated with: blepharoconjunctivitis (21/32 eyes, 66%), iritis (29/32 eyes, 91%), corneal edema (32/32 eyes, 100%), and subepithelial corneal infiltrates (30/32 eyes, 94%). Seroconversion was demonstrated in 26 of 31 rabbits (84%). The study concludes that a potentially useful animal model of adenoviral ocular infection can be attained.  (+info)

Genetic modulation of antigen presentation by HLA-B27 molecules. (8/48)

In studies of antigenic peptide presentation, we have found a healthy volunteer whose lymphoblastoid cells were unable to present three different virus-derived epitopes to cytotoxic T lymphocytes (CTL) despite expressing the correct restricting HLA-B27 molecules on the cell surface. B cell lines were established from other members of the donor's family, including individuals suffering from ankylosing spondylitis and related diseases, and were tested for their ability to function as target cells in the same assay. None of the eight B cell lines that expressed HLA-B27 presented a known peptide epitope to CTL. However, cells from a family member that expressed HLA-B8 could present an epitope peptide restricted by that molecule. The B27 molecule in this family proved to be the B2702 subtype on isoelectric focusing gels, appearing in exactly the same position as B2702 from other cell lines that did present the peptide. To exclude mutations resulting in noncharged amino acid substitutions, cDNA coding for B2702 was cloned from the proband's cell line and sequenced. No coding changes were found. The cloned cDNA was transfected into HLA-A- and B-negative HMy/C1R cells, and the B2702 molecules generated in this environment rendered these cells, after incubation with peptide, susceptible to lysis by peptide-specific CTL. These data are compatible with the presence of a factor(s), possibly HLA linked, interfering with antigen presentation by otherwise normal B2702 molecules in this family.  (+info)

Iritis, also known as anterior uveitis, is a type of inflammatory eye disease that affects the iris, which is the coloured part of the eye. It is a condition where the iris becomes inflamed, leading to pain, redness, and blurred vision.

Causes:

The exact cause of iritis is not known, but it is believed to be an autoimmune response, where the body's immune system mistakenly attacks healthy tissue in the eye. It can also be triggered by an infection or injury.

Symptoms:

The symptoms of iritis can vary depending on the severity of the condition, but common signs include:

* Eye pain, which can be severe
* Redness and inflammation of the eye
* Blurred vision or sensitivity to light
* Seeing floaters or flashes of light
* Sensitivity to touch or pressure on the eye

Diagnosis:

Iritis is diagnosed based on a comprehensive eye exam, which includes a visual acuity test, dilated eye exam, and tonometry. The doctor may also perform additional tests such as a fluorescein dye test or imaging studies to rule out other conditions.

Treatment:

The treatment of iritis typically involves a combination of medications and therapies, including:

* Corticosteroids to reduce inflammation
* Anti-inflammatory eye drops or ointments
* Pain relief medication
* Warm compresses to the affected eye
* Eye exercises to improve vision
* In severe cases, surgery may be necessary to remove the inflamed tissue

Prognosis:

The prognosis for iritis is generally good if treated promptly and effectively. However, if left untreated, it can lead to complications such as cataracts, glaucoma, or permanent vision loss. It is important to seek medical attention immediately if symptoms persist or worsen over time.

Prevention:

There is no known prevention for iritis, but early detection and treatment can help reduce the risk of complications. Regular eye exams and awareness of the signs and symptoms can help identify the condition in its early stages.

Complications:

Iritis can lead to several complications if left untreated or if the inflammation is not properly managed. These may include:

* Cataracts: The inflammation can cause clouding of the lens, leading to vision loss.
* Glaucoma: The increased pressure in the eye can lead to damage to the optic nerve and vision loss.
* Permanent vision loss: If the inflammation is not properly managed, it can lead to permanent vision loss.
* Increased risk of infection: Iritis can increase the risk of infection, particularly if the eye is not properly cleaned and cared for.

Conclusion:

Iritis is a painful and potentially sight-threatening condition that can cause inflammation in the iris of the eye. Early detection and prompt treatment are crucial to prevent complications and preserve vision. A comprehensive understanding of the signs, symptoms, diagnosis, treatment, prognosis, prevention, and complications of iritis is essential for effective management of this condition. If you suspect you or someone you know may have iritis, it is important to seek medical attention promptly to ensure proper diagnosis and treatment.

There are several different types of conjunctivitis, including:

1. Allergic conjunctivitis: This type is caused by an allergic reaction and is more common in people who have a history of allergies.
2. Bacterial conjunctivitis: This type is caused by a bacterial infection and is often accompanied by a thick discharge and redness of the eye.
3. Viral conjunctivitis: This type is caused by a viral infection and is highly contagious.
4. Chemical conjunctivitis: This type is caused by exposure to chemicals or foreign objects, such as smoke, dust, or pollen.
5. Irritant conjunctivitis: This type is caused by exposure to irritants such as chemicals or foreign objects.

Symptoms of conjunctivitis can include redness and discharge of the eye, itching, burning, and tearing. Treatment typically involves antibiotic eye drops or ointments for bacterial conjunctivitis, anti-inflammatory medication for allergic conjunctivitis, and viral conjunctivitis is usually self-limiting and requires supportive care only.

It's important to note that conjunctivitis can be highly contagious, so it's important to practice good hygiene, such as washing your hands frequently, avoiding sharing personal items like towels or makeup, and not touching the eyes. If you suspect you have conjunctivitis, it's important to see a healthcare professional for proper diagnosis and treatment.

Iritis can occur, too. Keratic precipitates are another eye manifestation (detectable by a slit lamp, but are usually too small ...
Anterior uveitis includes iridocyclitis and iritis. Iritis is the inflammation of the anterior chamber and iris. Iridocyclitis ... 66% - 90% of uveitis cases are anterior in location (iritis). This condition can occur as a single episode and subside with ...
In his prize-winning book, De Iritide (1835), he made contributions involving investigations of iritis and sympathetic ... De Iritide, (Berlin, 1843) - Treatise on iritis. Illustrierte pathologische Anatomie der menschlichen Kornea, Sklera, Choroidea ...
Lakin, C. E. (1917). "Discussion on the Ætiology and Treatment of Iritis". Proceedings of the Royal Society of Medicine. 10 ( ...
In 1982, Rotenstein reported a family with granulomatous arteritis, rash, iritis, and arthritis transmitted as an autosomal ... Blau EB : Familial Granulomatous Arthritis, Iritis, and Rash. The Journal of Pediatrics 1985; 107: 689-693. PMID 4056967. doi: ...
Local corticosteroids are useful in the case of iritis.[citation needed] Reactive arthritis may be self-limiting, frequently ...
Complications can include bacterial keratitis, corneal ulcer, and iritis. Complications may occur in up to 8% of people. Signs ...
Conjunctivitis and iritis of the anterior segment of the eye. The early investigators of onchocerciasis from 1874-1930 in ...
Other risk factors include narrow-angle glaucoma, aging, and iritis. A rare disease called X-linked endothelial corneal ...
... enlisted with First AIF but repatriated due to iritis 1917. W. F. Dind married again, to Emily Rosetta Horne, née Paterson, ...
3-5. Adamantiades B. A case of relapsing iritis with hypopyon (in Greek). Archeia Iatrikis Etairias (Proceedings of the Medical ... "A case of relapsing iritis with hypopyon" identifying the three major signs of the so-called Adamantiades-Behçet's disease and ...
Lyons 2000, p. 306: "The iritis may have been caused by ... Reiter's disease. This follows a chlamydial infection; This may ...
There is no iritis, corneal stroma or breech of Bowman's membrane. The ulceration can be accompanied by conjunctivitis, without ...
... iritis, and conjunctivitis. Patients may be asymptomatic or experience redness, burning, or itching in eyes (CITE CMDP). ... Inflammation may occur in the interior portion of the eye, leading to uveitis and iritis. Uveitis can cause blurred vision and ...
Campbell was afflicted lifelong by ankylosing spondylitis, and by bouts of iritis. He died on 3 May 1993. While studying for ...
More severe exposures can result in keratitis, iritis, corneal perforation, and blindness. Respiratory: Irritation of the ...
... iritis, iridocyclitis, anterior uveitis, sympathetic ophthalmia, and uveal melanoma. Oxford English Dictionary: uvea Lidell and ...
Possible problems could be displacement of the iris, iritis and raised intraocular pressure. A clinician should also be able to ...
iritis - together with the ciliary body and choroid, the iris makes up the uvea, part of the middle, pigmented, structures of ... In iritis and traumatic perforating ocular injuries, the intraocular pressure is usually low. Those with conjunctivitis may ...
It is usually associated with urethritis, conjunctivitis, iritis, painless buccal ulcers, and keratoderma blennorrhagica. Axial ...
In the early 1950s, Huxley had suffered a debilitating attack of the eye condition iritis. This increased his concern for his ...
Lessons on inflammatory diseases of the internal membranes of the eye including iritis, choroiditis, and glaucoma. Traité des ...
The only incongruity was the dark glasses he was forced to always wear because of chronic iritis. Throughout his political life ...
These cells fight off intraocular infections, and intraocular inflammation can manifest as uveitis (including iritis) or ...
In January 2011, she revealed her struggle with chronic iritis that had caused temporary blindness in one eye. Some months ...
If the pupil can be fully dilated during the treatment of iritis, the prognosis for recovery from synechia is good. This is a ... iritis or iridocyclitis and may lead to certain types of glaucoma. It is sometimes visible on careful examination but usually ...
Some more serious conditions can present with a red eye, such as infectious keratitis, angle-closure glaucoma, or iritis. These ... Viral conjunctivitis manifests as a fine, diffuse pinkness of the conjunctiva which may be mistaken for iritis, but ...
Iritis is an inflammatory condition in which aqueouscellsarepresent, but aqueous cells in Schwartz Matsuo syndrome are ...
Ophthalmologists had described the ocular symptoms as iritis, which might be the result of syphilis, tuberculosis or ...
It is a sign of inflammation of the anterior uvea and iris, i.e. iritis, which is a form of anterior uveitis. The exudate ...
Iritis.org. This is an informative website on iritis to help those that suffer and those researching the disease. ...
Traumatic iritis. Traumatic iritis is inflammation of the colored part of the eye (the iris) that surrounds the pupil and ... Traumatic iritis can be caused by a poke in the eye or a blow to the eye from a blunt object, such as a ball or a hand. ... Traumatic iritis usually requires treatment. Even with medical treatment, there is a risk of permanent decreased vision. ...
Iritis. Inflammation of the iris of the eye.. Irrigation. Continuous washing.. IV. Intravenously.. ...
Tumor lysis syndrome refers to the constellation of metabolic disturbances that may follow the initiation of cancer treatment. It usually occurs in patients with bulky, rapidly proliferating, treatment-responsive tumors.
Iritis. Oesophagus, stricture of.. catarrh of. Phthisis mucosa. Pleurisy. Pneumonia. Bothrops Lanceolatus Snake-bites. Sneezing ...
Ocular: Uveitis, iritis, other ocular inflammatory toxicities. Some cases can be associated with retinal detachment. Various ...
Intraocular inflammation (iritis/uveitis) [ see Warnings and Precautions (5.3)] *Macular edema, including cystoid macular edema ... Latanoprost should be used with caution in patients with a history of intraocular inflammation (iritis/uveitis) and should ... iritis/uveitis); macular edema, including cystoid macular edema; misdirected eyelashes sometimes resulting in eye irritation; ...
iritis/uveitis. eye surgery. eye trauma. loss of vision. *. Do you have any medical conditions (including treated conditions)?* ...
... iritis and other ocular inflammatory toxicities can occur. Some cases can be associated with retinal detachment. Various grades ...
Night, worse at, or in damp weather (iritis) :- Merc.. Brilliant :- th., Amyg., Bell., Camph., Cann-i., Gels., Hyos., Mill., ... Using, on, it, in right (rheumatic iritis) :- Syph.. Vision, in and over, with blurring of, after using eyes and straining them ... Fire, a ball of, as if it were (kerato-iritis with hypopion) :- Merc. ...
Iritis , Strabismus , 10 , Diseases of Central Nervous system , Encephalitis , Encephalomyelitis , Epilepsy , Mastoiditis , ...
In this case, the condition is called iritis. In most cases, it occurs in healthy people. The disorder may affect only one eye ...
... iritis (dexamethasone insert, 4.0%; placebo, 9.1%), and corneal edema (dexamethasone insert, 1.6%; placebo, 5.5%). Given the ...
The vapor also acts quickly, with pain on contact, followed by edema of the conjunctiva and eyelids, and iritis and corneal ... Contact with liquid or vapor forms may result in skin erythema and blistering, corneal damage and iritis, damage to the airway ... With high doses, corneal damage and iritis may follow. Liquid Lewisite causes severe eye damage on contact. Mustard-Lewisite ...
Syphilitic iritis. ICD-9-CM Volume 2 Index entries containing back-references to 091.52:. *Iridocyclitis NEC 364.3. *. ...
... und Folgekrankheit von Iritis," in "Archiv für Augenheilkunde," v.; "Zur Lehre vom Glaucom," ib. vii., xvi.; "Zur Lehre von der ...
La iritis traumática fue el diagnóstico más frecuente, seguido de lesión periocular, lesiones de polo anterior, conmoción ... Traumatic iritis was the mostfrequent diagnosis, followed by periocular lesions, anterior segment lesions, conmotio retinae, ... Eye injuries; Sports practice; Soccer; Emergencies; Iritis. Subjects:. Medical sciences , Medicine , Sports medicine. Medical ... Traumatismo ocular; Práctica deportiva; Fútbol; Urgencias; Iritis. Palabras clave (otros idiomas):. ...
Iritis, noted in 3/3 eyes, cleared by day 7. Conjunctival irritation, noted in 3/3 eyes, cleared by day 14. ... The opacity cleared by Day 7. Iritis, noted in 3/3 eyes (average scores: 0.3/1/0.3), cleared by Day 7. Conjunctival redness, ...
Iritis. 1-5%. *Lacrimation increased. *Corneal edema. *Aqueous humor leakage. *Iris adhesions ...
Severe iritis occurred in two eyes and hyphema occurred in three eyes. No instances of hypotony or phthisis bulbi were reported ...
... an inflammation in the eye called iritis, which can be idiopathic (arising from an unknown cause). It could also be a sign of ...
Acute anterior uveitis (iritis) is a painful condition causing photophobia and blepharospasm. Episcleral hyperemia is less ...
In the animals receiving the test item, iritis was observed in one of three rabbits at 1 hour post treatment. Scores for ...
Onchocerciasis has been recognized to be related to posterior uveitis as well as keratitis and iritis. This raises blood ...
Iritis and iridocyclitis. 7. Respiratory Diseases. Symptomatic sarcoidosis. Loefflers syndrome not manageable by other means. ...
Iritis can accompany bacterial or viral keratitis or posterior segment infections or may be associated solely with HIV ... 19] Cidofovir, used in the treatment of cytomegalovirus retinitis (CMVR), can also cause iritis and occasionally hypotony. [20] ... Certain drugs used in the treatment of HIV-related conditions can cause drug-induced iritis. Rifabutin is used in the treatment ... of mycobacterium-avium complex infection and can produce severe hypopyon iritis that may be confused with endogenous ...
Iritis (anterior uveitis) has been associated with a few cases of relapsing fever in the southwestern United States (27), which ...
Elevated serum creatinine, proteinuria, neutropenia, ocular hypotony, uveitis, iritis, metabolic acidosis, GI disturbances, ...
  • Learn more about iritis and uveitis by reading related articles. (iritis.org)
  • Find an iritis/uveitis doctor close to you. (iritis.org)
  • Iritis and irido-cyclitis (anterior uveitis) are most often mild. (medlineplus.gov)
  • Acute anterior uveitis (iritis) is a painful condition causing photophobia and blepharospasm. (vin.com)
  • The vapor also acts quickly, with pain on contact, followed by edema of the conjunctiva and eyelids, and iritis and corneal damage with high doses. (cdc.gov)
  • Método: Recopilación retrospectiva de los datos clínicos de los pacientes que acudieron al servicio de urgencias del Hospital Clínico San Carlos en el periodo enero 2015-diciembre 2017 y que habían sufrido un traumatismo ocular durante la práctica de algún deporte. (ucm.es)
  • Traumatic iritis was the mostfrequent diagnosis, followed by periocular lesions, anterior segment lesions, conmotio retinae, rhegmatogenous lesions, orbital fracture and retinal detachment. (ucm.es)
  • This is an informative website on iritis to help those that suffer and those researching the disease. (iritis.org)
  • This condition allows both protein and WBCs to extravasate into the aqueous, resulting in the signs of cell and flare which are typical of iritis. (medscape.com)
  • consensual photophobia is typical of iritis, whereas photophobia due to more superficial causes, such as conjunctivitis, is direct but not consensual. (medscape.com)
  • Iritis, or anterior uveitis, is the most common form of intraocular inflammation. (medscape.com)
  • Iritis is the most frequent form of uveitis encountered by ophthalmologists. (medscape.com)
  • Iritis and irido-cyclitis (anterior uveitis) are most often mild. (medlineplus.gov)
  • Inflammation of the iris may appropriately be termed iritis, whereas inflammation of the iris and the ciliary body is called iridocyclitis. (medscape.com)
  • There are different forms of ocular vaccinia: blepharitis (inflammation of the eyelid), conjunctivitis, keratitis (inflammation of the cornea, including epithelial and stromal forms), iritis, or combinations thereof. (cdc.gov)
  • Frequently, the cause is idiopathic, but certain ocular and systemic diseases may be the underlying cause of the iritis. (medscape.com)
  • Morbidity arises from iritis and any associated disease process, if present. (medscape.com)