Pituitary Neoplasms
Meningioma
Meningeal Neoplasms
Brain Neoplasms
Pituitary Gland
Pituitary Gland, Anterior
Pituitary Diseases
Pituitary Hormones
Pituitary Apoplexy
Pancreatic Neoplasms
Neoplasms
Pituitary Hormones, Anterior
Neoplasms, Cystic, Mucinous, and Serous
Pituitary Adenylate Cyclase-Activating Polypeptide
Pituitary Gland, Posterior
Prolactin
Pituitary neoplasms refer to abnormal growths or tumors in the pituitary gland, a small endocrine gland located at the base of the brain. These neoplasms can be benign (non-cancerous) or malignant (cancerous), with most being benign. They can vary in size and may cause various symptoms depending on their location, size, and hormonal activity.
Pituitary neoplasms can produce and secrete excess hormones, leading to a variety of endocrine disorders such as Cushing's disease (caused by excessive ACTH production), acromegaly (caused by excessive GH production), or prolactinoma (caused by excessive PRL production). They can also cause local compression symptoms due to their size, leading to headaches, vision problems, and cranial nerve palsies.
The exact causes of pituitary neoplasms are not fully understood, but genetic factors, radiation exposure, and certain inherited conditions may increase the risk of developing these tumors. Treatment options for pituitary neoplasms include surgical removal, radiation therapy, and medical management with drugs that can help control hormonal imbalances.
A meningioma is a type of slow-growing tumor that forms on the membranes (meninges) surrounding the brain and spinal cord. It's usually benign, meaning it doesn't spread to other parts of the body, but it can still cause serious problems if it grows and presses on nearby tissues.
Meningiomas most commonly occur in adults, and are more common in women than men. They can cause various symptoms depending on their location and size, including headaches, seizures, vision or hearing problems, memory loss, and changes in personality or behavior. In some cases, they may not cause any symptoms at all and are discovered only during imaging tests for other conditions.
Treatment options for meningiomas include monitoring with regular imaging scans, surgery to remove the tumor, and radiation therapy to shrink or kill the tumor cells. The best treatment approach depends on factors such as the size and location of the tumor, the patient's age and overall health, and their personal preferences.
Meningeal neoplasms, also known as malignant meningitis or leptomeningeal carcinomatosis, refer to cancerous tumors that originate in the meninges, which are the membranes covering the brain and spinal cord. These tumors can arise primarily from the meningeal cells themselves, although they more commonly result from the spread (metastasis) of cancer cells from other parts of the body, such as breast, lung, or melanoma.
Meningeal neoplasms can cause a variety of symptoms, including headaches, nausea and vomiting, mental status changes, seizures, and focal neurological deficits. Diagnosis typically involves imaging studies (such as MRI) and analysis of cerebrospinal fluid obtained through a spinal tap. Treatment options may include radiation therapy, chemotherapy, or surgery, depending on the type and extent of the tumor. The prognosis for patients with meningeal neoplasms is generally poor, with a median survival time of several months to a year.
Brain neoplasms, also known as brain tumors, are abnormal growths of cells within the brain. These growths can be benign (non-cancerous) or malignant (cancerous). Benign brain tumors typically grow slowly and do not spread to other parts of the body. However, they can still cause serious problems if they press on sensitive areas of the brain. Malignant brain tumors, on the other hand, are cancerous and can grow quickly, invading surrounding brain tissue and spreading to other parts of the brain or spinal cord.
Brain neoplasms can arise from various types of cells within the brain, including glial cells (which provide support and insulation for nerve cells), neurons (nerve cells that transmit signals in the brain), and meninges (the membranes that cover the brain and spinal cord). They can also result from the spread of cancer cells from other parts of the body, known as metastatic brain tumors.
Symptoms of brain neoplasms may vary depending on their size, location, and growth rate. Common symptoms include headaches, seizures, weakness or paralysis in the limbs, difficulty with balance and coordination, changes in speech or vision, confusion, memory loss, and changes in behavior or personality.
Treatment for brain neoplasms depends on several factors, including the type, size, location, and grade of the tumor, as well as the patient's age and overall health. Treatment options may include surgery, radiation therapy, chemotherapy, targeted therapy, or a combination of these approaches. Regular follow-up care is essential to monitor for recurrence and manage any long-term effects of treatment.
The pituitary gland is a small, endocrine gland located at the base of the brain, in the sella turcica of the sphenoid bone. It is often called the "master gland" because it controls other glands and makes the hormones that trigger many body functions. The pituitary gland measures about 0.5 cm in height and 1 cm in width, and it weighs approximately 0.5 grams.
The pituitary gland is divided into two main parts: the anterior lobe (adenohypophysis) and the posterior lobe (neurohypophysis). The anterior lobe is further divided into three zones: the pars distalis, pars intermedia, and pars tuberalis. Each part of the pituitary gland has distinct functions and produces different hormones.
The anterior pituitary gland produces and releases several important hormones, including:
* Growth hormone (GH), which regulates growth and development in children and helps maintain muscle mass and bone strength in adults.
* Thyroid-stimulating hormone (TSH), which controls the production of thyroid hormones by the thyroid gland.
* Adrenocorticotropic hormone (ACTH), which stimulates the adrenal glands to produce cortisol and other steroid hormones.
* Follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which regulate reproductive function in both males and females.
* Prolactin, which stimulates milk production in pregnant and lactating women.
The posterior pituitary gland stores and releases two hormones that are produced by the hypothalamus:
* Antidiuretic hormone (ADH), which helps regulate water balance in the body by controlling urine production.
* Oxytocin, which stimulates uterine contractions during childbirth and milk release during breastfeeding.
Overall, the pituitary gland plays a critical role in maintaining homeostasis and regulating various bodily functions, including growth, development, metabolism, and reproductive function.
The anterior pituitary, also known as the adenohypophysis, is the front portion of the pituitary gland. It is responsible for producing and secreting several important hormones that regulate various bodily functions. These hormones include:
* Growth hormone (GH), which stimulates growth and cell reproduction in bones and other tissues.
* Thyroid-stimulating hormone (TSH), which regulates the production of thyroid hormones by the thyroid gland.
* Adrenocorticotropic hormone (ACTH), which stimulates the adrenal glands to produce cortisol and other steroid hormones.
* Follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which regulate reproductive function in both males and females by controlling the development and release of eggs or sperm.
* Prolactin, which stimulates milk production in pregnant and nursing women.
* Melanocyte-stimulating hormone (MSH), which regulates skin pigmentation and appetite.
The anterior pituitary gland is controlled by the hypothalamus, a small region of the brain located just above it. The hypothalamus produces releasing and inhibiting hormones that regulate the secretion of hormones from the anterior pituitary. These hormones are released into a network of blood vessels called the portal system, which carries them directly to the anterior pituitary gland.
Damage or disease of the anterior pituitary can lead to hormonal imbalances and various medical conditions, such as growth disorders, thyroid dysfunction, adrenal insufficiency, reproductive problems, and diabetes insipidus.
Pituitary diseases refer to a group of conditions that affect the pituitary gland, a small endocrine gland located at the base of the brain. The pituitary gland is responsible for producing and secreting several important hormones that regulate various bodily functions, including growth and development, metabolism, stress response, and reproduction.
Pituitary diseases can be classified into two main categories:
1. Pituitary tumors: These are abnormal growths in or around the pituitary gland that can affect its function. Pituitary tumors can be benign (non-cancerous) or malignant (cancerous), and they can vary in size. Some pituitary tumors produce excess hormones, leading to a variety of symptoms, while others may not produce any hormones but can still cause problems by compressing nearby structures in the brain.
2. Pituitary gland dysfunction: This refers to conditions that affect the normal function of the pituitary gland without the presence of a tumor. Examples include hypopituitarism, which is a condition characterized by decreased production of one or more pituitary hormones, and Sheehan's syndrome, which occurs when the pituitary gland is damaged due to severe blood loss during childbirth.
Symptoms of pituitary diseases can vary widely depending on the specific condition and the hormones that are affected. Treatment options may include surgery, radiation therapy, medication, or a combination of these approaches.
Pituitary hormones are chemical messengers produced and released by the pituitary gland, a small endocrine gland located at the base of the brain. The pituitary gland is often referred to as the "master gland" because it controls several other endocrine glands and regulates various bodily functions.
There are two main types of pituitary hormones: anterior pituitary hormones and posterior pituitary hormones, which are produced in different parts of the pituitary gland and have distinct functions.
Anterior pituitary hormones include:
1. Growth hormone (GH): regulates growth and metabolism.
2. Thyroid-stimulating hormone (TSH): stimulates the thyroid gland to produce thyroid hormones.
3. Adrenocorticotropic hormone (ACTH): stimulates the adrenal glands to produce cortisol and other steroid hormones.
4. Follicle-stimulating hormone (FSH) and luteinizing hormone (LH): regulate reproductive function in both males and females.
5. Prolactin: stimulates milk production in lactating women.
6. Melanocyte-stimulating hormone (MSH): regulates skin pigmentation and appetite.
Posterior pituitary hormones include:
1. Oxytocin: stimulates uterine contractions during childbirth and milk ejection during lactation.
2. Vasopressin (antidiuretic hormone, ADH): regulates water balance in the body by controlling urine production in the kidneys.
Overall, pituitary hormones play crucial roles in regulating growth, development, metabolism, reproductive function, and various other bodily functions. Abnormalities in pituitary hormone levels can lead to a range of medical conditions, such as dwarfism, acromegaly, Cushing's disease, infertility, and diabetes insipidus.
Pituitary apoplexy is a medical emergency that involves bleeding into the pituitary gland (a small gland at the base of the brain) and/or sudden swelling of the pituitary gland. This can lead to compression of nearby structures, such as the optic nerves and the hypothalamus, causing symptoms like severe headache, visual disturbances, hormonal imbalances, and altered mental status. It is often associated with a pre-existing pituitary tumor (such as a pituitary adenoma), but can also occur in individuals without any known pituitary abnormalities. Immediate medical attention is required to manage this condition, which may include surgical intervention, hormone replacement therapy, and supportive care.
Pancreatic neoplasms refer to abnormal growths in the pancreas that can be benign or malignant. The pancreas is a gland located behind the stomach that produces hormones and digestive enzymes. Pancreatic neoplasms can interfere with the normal functioning of the pancreas, leading to various health complications.
Benign pancreatic neoplasms are non-cancerous growths that do not spread to other parts of the body. They are usually removed through surgery to prevent any potential complications, such as blocking the bile duct or causing pain.
Malignant pancreatic neoplasms, also known as pancreatic cancer, are cancerous growths that can invade and destroy surrounding tissues and organs. They can also spread (metastasize) to other parts of the body, such as the liver, lungs, or bones. Pancreatic cancer is often aggressive and difficult to treat, with a poor prognosis.
There are several types of pancreatic neoplasms, including adenocarcinomas, neuroendocrine tumors, solid pseudopapillary neoplasms, and cystic neoplasms. The specific type of neoplasm is determined through various diagnostic tests, such as imaging studies, biopsies, and blood tests. Treatment options depend on the type, stage, and location of the neoplasm, as well as the patient's overall health and preferences.
An adenoma is a benign (noncancerous) tumor that develops from glandular epithelial cells. These types of cells are responsible for producing and releasing fluids, such as hormones or digestive enzymes, into the surrounding tissues. Adenomas can occur in various organs and glands throughout the body, including the thyroid, pituitary, adrenal, and digestive systems.
Depending on their location, adenomas may cause different symptoms or remain asymptomatic. Some common examples of adenomas include:
1. Colorectal adenoma (also known as a polyp): These growths occur in the lining of the colon or rectum and can develop into colorectal cancer if left untreated. Regular screenings, such as colonoscopies, are essential for early detection and removal of these polyps.
2. Thyroid adenoma: This type of adenoma affects the thyroid gland and may result in an overproduction or underproduction of hormones, leading to conditions like hyperthyroidism (overactive thyroid) or hypothyroidism (underactive thyroid).
3. Pituitary adenoma: These growths occur in the pituitary gland, which is located at the base of the brain and controls various hormonal functions. Depending on their size and location, pituitary adenomas can cause vision problems, headaches, or hormonal imbalances that affect growth, reproduction, and metabolism.
4. Liver adenoma: These rare benign tumors develop in the liver and may not cause any symptoms unless they become large enough to press on surrounding organs or structures. In some cases, liver adenomas can rupture and cause internal bleeding.
5. Adrenal adenoma: These growths occur in the adrenal glands, which are located above the kidneys and produce hormones that regulate stress responses, metabolism, and blood pressure. Most adrenal adenomas are nonfunctioning, meaning they do not secrete excess hormones. However, functioning adrenal adenomas can lead to conditions like Cushing's syndrome or Conn's syndrome, depending on the type of hormone being overproduced.
It is essential to monitor and manage benign tumors like adenomas to prevent potential complications, such as rupture, bleeding, or hormonal imbalances. Treatment options may include surveillance with imaging studies, medication to manage hormonal issues, or surgical removal of the tumor in certain cases.
Neoplasms are abnormal growths of cells or tissues in the body that serve no physiological function. They can be benign (non-cancerous) or malignant (cancerous). Benign neoplasms are typically slow growing and do not spread to other parts of the body, while malignant neoplasms are aggressive, invasive, and can metastasize to distant sites.
Neoplasms occur when there is a dysregulation in the normal process of cell division and differentiation, leading to uncontrolled growth and accumulation of cells. This can result from genetic mutations or other factors such as viral infections, environmental exposures, or hormonal imbalances.
Neoplasms can develop in any organ or tissue of the body and can cause various symptoms depending on their size, location, and type. Treatment options for neoplasms include surgery, radiation therapy, chemotherapy, immunotherapy, and targeted therapy, among others.
Anterior pituitary hormones are a group of six major hormones that are produced and released by the anterior portion (lobe) of the pituitary gland, a small endocrine gland located at the base of the brain. These hormones play crucial roles in regulating various bodily functions and activities. The six main anterior pituitary hormones are:
1. Growth Hormone (GH): Also known as somatotropin, GH is essential for normal growth and development in children and adolescents. It helps regulate body composition, metabolism, and bone density in adults.
2. Prolactin (PRL): A hormone that stimulates milk production in females after childbirth and is also involved in various reproductive and immune functions in both sexes.
3. Follicle-Stimulating Hormone (FSH): FSH regulates the development, growth, and maturation of follicles in the ovaries (in females) and sperm production in the testes (in males).
4. Luteinizing Hormone (LH): LH plays a key role in triggering ovulation in females and stimulating testosterone production in males.
5. Thyroid-Stimulating Hormone (TSH): TSH regulates the function of the thyroid gland, which is responsible for producing and releasing thyroid hormones that control metabolism and growth.
6. Adrenocorticotropic Hormone (ACTH): ACTH stimulates the adrenal glands to produce cortisol, a steroid hormone involved in stress response, metabolism, and immune function.
These anterior pituitary hormones are regulated by the hypothalamus, which is located above the pituitary gland. The hypothalamus releases releasing and inhibiting factors that control the synthesis and secretion of anterior pituitary hormones, creating a complex feedback system to maintain homeostasis in the body.
Neoplasms: Neoplasms refer to abnormal growths of tissue that can be benign (non-cancerous) or malignant (cancerous). They occur when the normal control mechanisms that regulate cell growth and division are disrupted, leading to uncontrolled cell proliferation.
Cystic Neoplasms: Cystic neoplasms are tumors that contain fluid-filled sacs or cysts. These tumors can be benign or malignant and can occur in various organs of the body, including the pancreas, ovary, and liver.
Mucinous Neoplasms: Mucinous neoplasms are a type of cystic neoplasm that is characterized by the production of mucin, a gel-like substance produced by certain types of cells. These tumors can occur in various organs, including the ovary, pancreas, and colon. Mucinous neoplasms can be benign or malignant, and malignant forms are often aggressive and have a poor prognosis.
Serous Neoplasms: Serous neoplasms are another type of cystic neoplasm that is characterized by the production of serous fluid, which is a thin, watery fluid. These tumors commonly occur in the ovary and can be benign or malignant. Malignant serous neoplasms are often aggressive and have a poor prognosis.
In summary, neoplasms refer to abnormal tissue growths that can be benign or malignant. Cystic neoplasms contain fluid-filled sacs and can occur in various organs of the body. Mucinous neoplasms produce a gel-like substance called mucin and can also occur in various organs, while serous neoplasms produce thin, watery fluid and commonly occur in the ovary. Both mucinous and serous neoplasms can be benign or malignant, with malignant forms often being aggressive and having a poor prognosis.
Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) is a neuropeptide that belongs to the vasoactive intestinal polypeptide (VIP)/secretin/glucagon family. It was first isolated from the ovine hypothalamus and later found in various tissues and organs throughout the body, including the brain, pituitary gland, and peripheral nerves.
PACAP exists in two forms, PACAP-38 and PACAP-27, which differ in their length but share the same amino acid sequence at the N-terminus. PACAP exerts its effects through specific G protein-coupled receptors, including PAC1, VPAC1, and VPAC2 receptors, which are widely distributed throughout the body.
PACAP has a wide range of biological activities, including neurotrophic, neuroprotective, vasodilatory, and immunomodulatory effects. In the pituitary gland, PACAP stimulates adenylate cyclase activity, leading to an increase in intracellular cAMP levels, which in turn regulates the release of various hormones, including growth hormone, prolactin, and thyroid-stimulating hormone.
Overall, PACAP is a crucial neuropeptide involved in various physiological processes, and its dysregulation has been implicated in several pathological conditions, such as neurodegenerative diseases, mood disorders, and cancer.
The posterior pituitary gland, also known as the neurohypophysis, is the posterior portion of the pituitary gland. It is primarily composed of nerve fibers that originate from the hypothalamus, a region of the brain. These nerve fibers release two important hormones: oxytocin and vasopressin (also known as antidiuretic hormone or ADH).
Oxytocin plays a role in social bonding, sexual reproduction, and childbirth. During childbirth, it stimulates uterine contractions to help facilitate delivery, and after birth, it helps to trigger the release of milk from the mother's breasts during breastfeeding.
Vasopressin, on the other hand, helps regulate water balance in the body by controlling the amount of water that is excreted by the kidneys. It does this by increasing the reabsorption of water in the collecting ducts of the kidney, which leads to a more concentrated urine and helps prevent dehydration.
Overall, the posterior pituitary gland plays a critical role in maintaining fluid balance, social bonding, and reproduction.
Prolactin is a hormone produced by the pituitary gland, a small gland located at the base of the brain. Its primary function is to stimulate milk production in women after childbirth, a process known as lactation. However, prolactin also plays other roles in the body, including regulating immune responses, metabolism, and behavior. In men, prolactin helps maintain the sexual glands and contributes to paternal behaviors.
Prolactin levels are usually low in both men and non-pregnant women but increase significantly during pregnancy and after childbirth. Various factors can affect prolactin levels, including stress, sleep, exercise, and certain medications. High prolactin levels can lead to medical conditions such as amenorrhea (absence of menstruation), galactorrhea (spontaneous milk production not related to childbirth), infertility, and reduced sexual desire in both men and women.
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Tumors33
- Pituitary adenomas are tumors that occur in the pituitary gland, and account for about 15% of intracranial neoplasms. (wikipedia.org)
- Pituiatry tumors account for about 15% of all intracranial neoplasms. (endocrine-abstracts.org)
- Glial cell tumors and pituitary tumors occur commonly in brachycephalic breeds, whereas meningiomas occur most frequently in dolichocephalic breeds. (vin.com)
- Secondary tumors reported to occur in the brain of cats include pituitary macroadenomas macrocarcinomas, and metastatic carcinomas. (vin.com)
- Pituitary gland neoplasms and tumors arising from cranial nerves are considered secondary brain tumors. (vin.com)
- Secondary effects of brain tumors include hydrocephalus, increased intracranial pressure (ICP), cerebral edema, and brain herniation. (vin.com)
- Overview of the 2022 WHO Classification of Pituitary Tumors. (nih.gov)
- Elevated survivin expression is normally proven in pituitary tumors but any research has not explored the survivin amounts in plasma however. (buyresearchchemicalss.net)
- Additional practical pituitary tumors had been excluded by powerful hormone tests in every patients. (buyresearchchemicalss.net)
- Having some other illnesses (malignancy, diabetes mellitus, hypertension, hyperlipidemia, coronary artery disease, chronic liver organ or kidney illnesses, gastrointestinal absorption complications, collagen cells disease, and thyroid disease), and additional practical or nonfunctional pituitary tumors had been thought as exclusion requirements. (buyresearchchemicalss.net)
- Tumors of the pituitary gland are usually benign adenomas and account for 10% of all intracranial neoplasms. (ox.ac.uk)
- Five pituitary tumors have previously been reported to harbor multiple allelic deletions. (ox.ac.uk)
- Accordingly, we studied two cohorts of pituitary tumors, classified radiologically as invasive or noninvasive, for loss of heterozygosity (LOH). (ox.ac.uk)
- Furthermore, in some tumors we identified a breakpoint between markers intragenic and extragenic to the retinoblastoma gene (Rb1) on chromosome 13q, suggesting that tumor suppressor genes other than or in addition to Rb1 may be involved in pituitary tumorigenesis. (ox.ac.uk)
- Pituitary carcinomas are rare neuroendocrine tumors affecting the adenohypophysis. (biomedcentral.com)
- Pituitary carcinomas are extremely rare neoplasms, representing only 0.1% to 0.2% of all pituitary tumors. (biomedcentral.com)
- As one of the four most common intracranial tumors (including brain metastases, meningiomas, gliomas, and pituitary tumors), pituitary adenomas are usually slow-growing. (vinmec.com)
- So are pituitary tumors dangerous? (vinmec.com)
- What treatments are there for pituitary tumors? (vinmec.com)
- 2. Are pituitary tumors dangerous? (vinmec.com)
- Most pituitary tumors are benign. (vinmec.com)
- The percentage of people with malignant pituitary tumors and needing treatment is very low. (vinmec.com)
- Of the total number of patients undergoing surgery for intracranial tumors, only 25% are due to pituitary tumors. (vinmec.com)
- Hypersecretory pituitary tumors: are tumors that arise from hormone-secreting cells. (vinmec.com)
- Non-secretory pituitary tumors: are tumors that arise from non-hormonal glandular cells, so the hormone in these patients is not increased or even decreased. (vinmec.com)
- Classification based on the growth rate of the tumor is divided into 2 groups: Slow-growing pituitary tumors. (vinmec.com)
- As with most other intracranial tumors, the cause of pituitary adenomas is still unknown. (vinmec.com)
- A few cases are due to genetics such as giantism in the family, some cases of pituitary tumors are found in the setting of multiple endocrine neoplasms of group 1. (vinmec.com)
- Many of these tumors typically only occur in childhood, including: PPB (before age 7), CN (before age 4), CBME typically occurs in young children, pituitary blastoma (before age 2), and childhood pineoblastoma (only one has been reported associated with a DICER1 mutation). (clinicalgenome.org)
- Over his lifetime, Cushing operated on countless intracranial tumors. (medscape.com)
- CT was quickly shown to be of value for the intracranial diagnosis and evaluation of primary tumors of the brain and surrounding structures. (ajnr.org)
- Cushing's is a disease of middle-aged to older cats (7-12 years), and may be caused by a pituitary tumor (90% are adenomas), pituitary hyperplasia, adrenal tumors, adrenal hyperplasia, by non-endocrine tumors (usually lung) or it may be iatrogenic. (dvm360.com)
- Representative H/E stain of pituitary adenoma xenografts generated from a limiting dilution of CD15 high and CD15 low adenomas demonstrate ( a ) tumors with a glandular morphology from CD15 high adenomas at a dilution of 1×10 5 cells ( n = 2, ×200) compared to ( b ) no apparent tumor formation in CD15 low xenografts at all dilutions ( n = 2, ×200). (biomedcentral.com)
Tumor19
- The long-acting somatostatin analogue octreotide is used either as an adjuvant or primary therapy to lower GH levels in patients with acromegaly and may also induce pituitary tumor shrinkage. (endocrine-abstracts.org)
- Therefore, we performed a meta-analysis to thoroughly assess the current literature on the effect of octreotide on pituitary tumor shrinkage. (endocrine-abstracts.org)
- Introduction: The human Pituitary Tumor Transforming Gene (hPTTG) is a phosphorylated proto-oncogene induced in multiple tumour types. (endocrine-abstracts.org)
- Cerebral meningioma is the most frequently reported primary brain tumor of cats and accounts for almost 10% of all nonhematopoietic neoplasms. (vin.com)
- We present a case of a patient who was found to have a growth hormone (GH)-secreting pituitary adenoma and a coexisting cavernous ICA aneurysm which was embedded within the tumor. (surgicalneurologyint.com)
- Prolactinoma may be the most common adult pituitary tumor accounting for 60% of useful pituitary adenomas [17]. (buyresearchchemicalss.net)
- Here, we report the case of a fatal pituitary carcinoma evolving within two years from an adrenocorticotrophic hormone (ACTH)-secreting macroadenoma and review the global literature regarding this rare neuroendocrine tumor. (biomedcentral.com)
- A pituitary tumor is a tumor that develops from cells of the pituitary gland. (vinmec.com)
- According to many studies, about 1 in 10 adults will have a pituitary tumor. (vinmec.com)
- The pituitary tumor grows larger and larger, pressing on the surrounding healthy pituitary cells, thereby reducing or disrupting hormone secretion. (vinmec.com)
- A large pituitary tumor (Macroadenoma) is a tumor of the pituitary gland that is 1 cm or larger. (vinmec.com)
- Fast-growing pituitary tumor. (vinmec.com)
- 3. What is the cause of pituitary tumor? (vinmec.com)
- Many patients, when undergoing treatment for infertility, found that prolactin levels were elevated when tested, and then tested to find a pituitary tumor. (vinmec.com)
- Patients with a history of growth hormone deficiency (GHD) secondary to an intracranial neoplasm should be routinely monitored during somatropin therapy for progression or recurrence of the tumor. (nutropin.com)
- Somatropin should not be used in patients with any evidence of progression or recurrence of an underlying intracranial tumor. (nutropin.com)
- Monitor all patients with a history of GHD secondary to an intracranial neoplasm routinely while on somatropin therapy for progression or recurrence of the tumor. (nutropin.com)
- All patients undergoing craniotomy or endoscopic endonasal removal of a brain, skull base or pituitary tumor were included during two non-overlapping periods: March 2019-January 2020 (pre-pandemic epoch) versus March 2020-January 2021 (pandemic epoch with streamlined care protocol implemented). (plos.org)
- CD15+ pituitary adenoma-initiating cells maintain their tumor initiation potential in human-mouse xenografts. (biomedcentral.com)
Adenoma6
- This case report is an illustration for physicians to be conscientious about the potential danger posed by the coexistence of an intratumoral aneurysm in the setting of a pituitary adenoma. (surgicalneurologyint.com)
- Background Prolactinoma may be the most common adult pituitary adenoma. (buyresearchchemicalss.net)
- The patients had been selected among whose preliminary serum prolactin amounts had been 250 buy Oxcarbazepine ng/mL as well as the pituitary MRI displaying adenoma Rabbit Polyclonal to GPR37 [18]. (buyresearchchemicalss.net)
- The latency period between initial presentation of a pituitary adenoma and the development of distal metastases marking carcinoma is extremely variable, and some patients may live well over 10 years with pituitary carcinoma. (biomedcentral.com)
- Finally, we screened for published case reports on pituitary adenoma, pituitary apoplexy, Rathke's cleft cyst, craniopharyngioma and hypophysitis. (medscape.com)
- The patient's face with GH-secreting pituitary adenoma is very special, the doctor can diagnose directly based on the observation of the face. (vinmec.com)
Gland7
- Intracranial neoplasms can arise from any of the structures or cell types present in the cranial vault, including the brain, meninges, pituitary gland, skull, and even residual embryonic tissue. (cancernetwork.com)
- A neoplasm that arises from the anterior or posterior lobe of pituitary gland and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. (nih.gov)
- The pituitary gland is an endocrine gland that secretes many important hormones that control the activities of many other endocrine glands in the body. (vinmec.com)
- 1. What is the pituitary gland? (vinmec.com)
- The pituitary gland is a hormone gland located in the brain. (vinmec.com)
- In addition, the pituitary gland also secretes hormones that have a beneficial effect. (vinmec.com)
- The pituitary gland has many different types of cells, each of which secretes a corresponding hormone and affects different organs of the body. (vinmec.com)
Apoplexy1
- Whereas in pituitary apoplexy a mechanical component explains the almost universal association of the condition with headaches, this correlation is less clear in other forms of pituitary disease and a positive impact of surgery on headaches is not guaranteed. (medscape.com)
Hydrocephalus2
- Increase in the total quantity of the intracranial fluid in the brain substance causes raised intracranial tension but not hydrocephalus as in pseudo motor cerebri or cerebral oedema. (biologydiscussion.com)
- Brain tumours are space occupying lesions and cause compression and destruction of adjacent structures, brain oedema (Peritumoural tissue), infarction and ischaemia of brain by compressing/infiltrating cerebral blood vessels, obstruction of CSF flow causing hydrocephalus, and rise in intracranial pressure with herniations. (jebmh.com)
Carcinoma1
- We describe a patient with an ACTH-producing carcinoma of the pituitary with refractory Cushing's disease and hepatic metastases. (biomedcentral.com)
Meningiomas3
- Main outcome measure Surgery (resection or decompression) or radiotherapy for one or more intracranial meningiomas. (bmj.com)
- Conclusions A strong dose-effect relation was observed between use of cyproterone acetate and risk of intracranial meningiomas. (bmj.com)
- Neuroepithelial tumours were the most common histological type followed by pituitary tumours and meningiomas. (jebmh.com)
Hemorrhage2
- However, there are concerns regarding the adverse effects associated with statin use in ischemic stroke such as intracranial hemorrhage. (neurologyindia.com)
- It was, however, a series of articles on the use of sonography for diagnosing and following intracranial hemorrhage (ICH) and its complications in the neonate that was to contribute most to the use of sonography in pediatric neuroradiology in these early years. (ajnr.org)
Idiopathic Intracranial1
- Dr. Patsalides has experience treating conditions like Idiopathic Intracranial Hypertension and Lumbar Spine Fracture among other conditions at varying frequencies. (sharecare.com)
Hypertension1
- Our literature review showed an early clinical onset due to intracranial hypertension signs. (thieme-connect.de)
Metastatic2
- Less commonly, pituitary carcinomas may metastasize hematogenously - a prominent feature of ACTH-producing carcinomas - resulting in metastatic invasion of the liver, bone, ovaries, heart, and lung. (biomedcentral.com)
- Only one case was metastatic in origin and in two patients the pituitary adenomas were confirmed. (jebmh.com)
Cavernous2
- This revealed a 2.8 × 2.1 × 1.7 cm homogeneous pituitary mass involving the sella turcica with extension into the right cavernous sinus. (biomedcentral.com)
- Tumour size, cavernous sinus invasion, traction or displacement of intracranial pain-sensitive structures such as blood vessels, cranial nerves and dura mater, and hormonal hypersecretion are implicated causes. (medscape.com)
Aneurysms2
- There is anecdotal evidence suggesting that intracranial aneurysms are coincidentally found significantly more frequently in the setting of pituitary adenomas than when the incidence is compared to other intracranial neoplasms. (surgicalneurologyint.com)
- 3 18 25 39 ] However, there is some evidence suggesting that coincidental intracranial aneurysms are found almost seven times more frequently in pituitary adenomas when compared to other intracranial neoplasms. (surgicalneurologyint.com)
Deficiency2
- The present review attempts to systematically review the literature for any combination of headache and pituitary or hormone overproduction or deficiency. (medscape.com)
- Patients who have severe growth hormone deficiency associated with multiple hormone deficiencies as a result of known hypothalamic or pituitary pathology, and who have at least one known deficiency of a pituitary hormone not being prolactin. (medicines.org.uk)
Tumour1
- Brain tumour, also known as intracranial tumour, is an abnormal mass of tissue arising from the cells within brain. (waocp.com)
Malignant neoplasm1
- Unspecified/other malignant neoplasm of skin of upper limb, incl. (cancer.gov)
Spinal1
- Intradural extramedullary spinal neoplasms: Radiologic-pathologic correlation. (msdmanuals.com)
Cancer1
- In childhood cancer survivors who were treated with radiation to the brain/head for their first neoplasm and who developed subsequent GHD and were treated with somatropin, an increased risk of a second neoplasm has been reported. (nutropin.com)
Disorders1
- In the following systematic review, we address the literature on headache and pituitary disorders with regard to prevalence, aetiology, pathophysiological mechanisms and treatment. (medscape.com)
Adrenal1
- He discovered the connection between the pituitary and adrenal glands, leading to the understanding of the eponymous Cushing syndrome and Cushing disease. (medscape.com)
Secondary1
- Undoubtedly Goliath's great size was due to ** **acromegaly ** **secondary to a pituitary macroadenoma. (serdarbalci.com)
Pathology1
- formation of extra-intracranial anastomoses with revascularizing purpose in cerebrovascular pathology. (kokbkirov.ru)
Endoscopic1
- Currently, microscopic or endoscopic transsphenoidal surgery (TSS) is the preferred method for the treatment of intrasellar pituitary adenomas. (surgicalneurologyint.com)
Arise1
- They arise from pituitary cell types due to both cell cycle trophic dysruptions leading to adenomatous growth, as well as a coupling of specific hormone gene over-expression. (endocrine-abstracts.org)
Carcinomas1
- Like adenomas, the vast majority of reported pituitary carcinomas are endocrinologically active (88%), with most secreting adrenocorticotrophic hormone (ACTH) or prolactin (PRL)[ 3 ]. (biomedcentral.com)
Occur1
- Brain neoplasms occur at all ages and account for around 2-3 percent of all deaths in adults. (jebmh.com)
Tumours4
- Cerebral hemisphere was the commonest site for intracranial tumours. (jebmh.com)
- Cerebrum was the commonest site of intracranial tumours. (jebmh.com)
- Majority of malignant intracranial tumours were WHO grade I. Rare variant like clear cell type was also observed. (jebmh.com)
- Brain tumours are mixed group of neoplasms originating from the intracranial tissues. (waocp.com)
Brain stem1
- Neoplasms involving the brain stem may result in cranial nerve deficits. (vin.com)