Intracranial Hemorrhages
Cerebral Hemorrhage
Intracranial Hemorrhage, Traumatic
Subarachnoid Hemorrhage
Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.
Tissue Plasminogen Activator
A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.
Hematoma, Subdural
Accumulation of blood in the SUBDURAL SPACE between the DURA MATER and the arachnoidal layer of the MENINGES. This condition primarily occurs over the surface of a CEREBRAL HEMISPHERE, but may develop in the spinal canal (HEMATOMA, SUBDURAL, SPINAL). Subdural hematoma can be classified as the acute or the chronic form, with immediate or delayed symptom onset, respectively. Symptoms may include loss of consciousness, severe HEADACHE, and deteriorating mental status.
Thrombolytic Therapy
Intracranial Arteriovenous Malformations
Congenital vascular anomalies in the brain characterized by direct communication between an artery and a vein without passing through the CAPILLARIES. The locations and size of the shunts determine the symptoms including HEADACHES; SEIZURES; STROKE; INTRACRANIAL HEMORRHAGES; mass effect; and vascular steal effect.
Tomography, X-Ray Computed
Stroke
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
Cerebral Angiography
Warfarin
An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.
Brain Ischemia
International Normalized Ratio
System established by the World Health Organization and the International Committee on Thrombosis and Hemostasis for monitoring and reporting blood coagulation tests. Under this system, results are standardized using the International Sensitivity Index for the particular test reagent/instrument combination used.
Hematoma
Postpartum Hemorrhage
Excess blood loss from uterine bleeding associated with OBSTETRIC LABOR or CHILDBIRTH. It is defined as blood loss greater than 500 ml or of the amount that adversely affects the maternal physiology, such as BLOOD PRESSURE and HEMATOCRIT. Postpartum hemorrhage is divided into two categories, immediate (within first 24 hours after birth) or delayed (after 24 hours postpartum).
Cerebral Hemorrhage, Traumatic
Treatment Outcome
Vasculitis, Central Nervous System
Inflammation of blood vessels within the central nervous system. Primary vasculitis is usually caused by autoimmune or idiopathic factors, while secondary vasculitis is caused by existing disease process. Clinical manifestations are highly variable but include HEADACHE; SEIZURES; behavioral alterations; INTRACRANIAL HEMORRHAGES; TRANSIENT ISCHEMIC ATTACK; and BRAIN INFARCTION. (From Adams et al., Principles of Neurology, 6th ed, pp856-61)
Gastrointestinal Hemorrhage
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Intracranial Aneurysm
Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (>2.5 cm in diameter) may compress adjacent structures, including the OCULOMOTOR NERVE. (From Adams et al., Principles of Neurology, 6th ed, p841)
Craniocerebral Trauma
Intracranial Hemorrhage, Hypertensive
Bleeding within the SKULL that is caused by systemic HYPERTENSION, usually in association with INTRACRANIAL ARTERIOSCLEROSIS. Hypertensive hemorrhages are most frequent in the BASAL GANGLIA; CEREBELLUM; PONS; and THALAMUS; but may also involve the CEREBRAL CORTEX, subcortical white matter, and other brain structures.
Hydrocephalus
Glasgow Coma Scale
Intracranial Hypertension
Echoencephalography
Embolectomy
Brain Hemorrhage, Traumatic
Magnetic Resonance Imaging
Prospective Studies
Hematoma, Subdural, Intracranial
Brain Damage, Chronic
A condition characterized by long-standing brain dysfunction or damage, usually of three months duration or longer. Potential etiologies include BRAIN INFARCTION; certain NEURODEGENERATIVE DISORDERS; CRANIOCEREBRAL TRAUMA; ANOXIA, BRAIN; ENCEPHALITIS; certain NEUROTOXICITY SYNDROMES; metabolic disorders (see BRAIN DISEASES, METABOLIC); and other conditions.
Cerebrovascular Disorders
Aneurysm, Ruptured
Platelet Transfusion
Thrombocytopenia, Neonatal Alloimmune
Fatal Outcome
Intracranial Thrombosis
Risk Factors
Neurologic Examination
Brain
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Obstetrical Forceps
Platelet Aggregation Inhibitors
Consciousness Disorders
Antigens, Human Platelet
Purpura, Thrombocytopenic, Idiopathic
Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.
Vitamin K Deficiency
Basal Ganglia Hemorrhage
Cerebral Infarction
The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).
Headache
Encephalocele
Brain tissue herniation through a congenital or acquired defect in the skull. The majority of congenital encephaloceles occur in the occipital or frontal regions. Clinical features include a protuberant mass that may be pulsatile. The quantity and location of protruding neural tissue determines the type and degree of neurologic deficit. Visual defects, psychomotor developmental delay, and persistent motor deficits frequently occur.
Vasospasm, Intracranial
Constriction of arteries in the SKULL due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and BRAIN ISCHEMIA that may lead to hypoxic-ischemic brain injury (HYPOXIA-ISCHEMIA, BRAIN).
Cerebral Ventricles
Skull Fractures
Fractures of the skull which may result from penetrating or nonpenetrating head injuries or rarely BONE DISEASES (see also FRACTURES, SPONTANEOUS). Skull fractures may be classified by location (e.g., SKULL FRACTURE, BASILAR), radiographic appearance (e.g., linear), or based upon cranial integrity (e.g., SKULL FRACTURE, DEPRESSED).
Infant, Newborn, Diseases
Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts.
Central Nervous System Vascular Malformations
Muscle Hypertonia
Anisocoria
Unequal pupil size, which may represent a benign physiologic variant or a manifestation of disease. Pathologic anisocoria reflects an abnormality in the musculature of the iris (IRIS DISEASES) or in the parasympathetic or sympathetic pathways that innervate the pupil. Physiologic anisocoria refers to an asymmetry of pupil diameter, usually less than 2mm, that is not associated with disease.
Phenylpropanolamine
Antifibrinolytic Agents
Embolization, Therapeutic
A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage.
Cranial Sinuses
Large endothelium-lined venous channels situated between the two layers of DURA MATER, the endosteal and the meningeal layers. They are devoid of valves and are parts of the venous system of dura mater. Major cranial sinuses include a postero-superior group (such as superior sagittal, inferior sagittal, straight, transverse, and occipital) and an antero-inferior group (such as cavernous, petrosal, and basilar plexus).
Fetal Diseases
Vacuum Extraction, Obstetrical
Postoperative Hemorrhage
Sinus Thrombosis, Intracranial
Formation or presence of a blood clot (THROMBUS) in the CRANIAL SINUSES, large endothelium-lined venous channels situated within the SKULL. Intracranial sinuses, also called cranial venous sinuses, include the superior sagittal, cavernous, lateral, petrous sinuses, and many others. Cranial sinus thrombosis can lead to severe HEADACHE; SEIZURE; and other neurological defects.
Thrombectomy
Follow-Up Studies
Incidence
Heparin
A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts.
Cohort Studies
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Extravasation of Diagnostic and Therapeutic Materials
Streptokinase
Arteriovenous Malformations
Abnormal formation of blood vessels that shunt arterial blood directly into veins without passing through the CAPILLARIES. They usually are crooked, dilated, and with thick vessel walls. A common type is the congenital arteriovenous fistula. The lack of blood flow and oxygen in the capillaries can lead to tissue damage in the affected areas.
Cerebral Revascularization
Microsurgical revascularization to improve intracranial circulation. It usually involves joining the extracranial circulation to the intracranial circulation but may include extracranial revascularization (e.g., subclavian-vertebral artery bypass, subclavian-external carotid artery bypass). It is performed by joining two arteries (direct anastomosis or use of graft) or by free autologous transplantation of highly vascularized tissue to the surface of the brain.
Vitamin K
A lipid cofactor that is required for normal blood clotting. Several forms of vitamin K have been identified: VITAMIN K 1 (phytomenadione) derived from plants, VITAMIN K 2 (menaquinone) from bacteria, and synthetic naphthoquinone provitamins, VITAMIN K 3 (menadione). Vitamin K 3 provitamins, after being alkylated in vivo, exhibit the antifibrinolytic activity of vitamin K. Green leafy vegetables, liver, cheese, butter, and egg yolk are good sources of vitamin K.
beta-Alanine
An amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. A rare genetic disorder, hyper-beta-alaninemia, has been reported.
Infusions, Intra-Arterial
Disseminated Intravascular Coagulation
Intracranial Pressure
Moyamoya Disease
A noninflammatory, progressive occlusion of the intracranial CAROTID ARTERIES and the formation of netlike collateral arteries arising from the CIRCLE OF WILLIS. Cerebral angiogram shows the puff-of-smoke (moyamoya) collaterals at the base of the brain. It is characterized by endothelial HYPERPLASIA and FIBROSIS with thickening of arterial walls. This disease primarily affects children but can also occur in adults.
Peptic Ulcer Hemorrhage
Risk Assessment
Brain Injuries
Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
Infusions, Intravenous
Posterior Cerebral Artery
Thromboembolism
Severity of Illness Index
Dura Mater
Arteriovenous Fistula
An abnormal direct communication between an artery and a vein without passing through the CAPILLARIES. An A-V fistula usually leads to the formation of a dilated sac-like connection, arteriovenous aneurysm. The locations and size of the shunts determine the degree of effects on the cardiovascular functions such as BLOOD PRESSURE and HEART RATE.
Pregnancy
Intracranial Embolism and Thrombosis
Nervous System Diseases
Brain Neoplasms
Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
Middle Cerebral Artery
Infarction, Middle Cerebral Artery
NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
Putaminal Hemorrhage
Brain Diseases
Age Factors
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Aneurysm, Infected
Prognosis
Seizures
Blood Coagulation Disorders
Randomized Controlled Trials as Topic
Atrial Fibrillation
Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.
Postoperative Complications
Magnetic Resonance Angiography
Purpura, Thrombocytopenic
Hospitals, Public
Delayed Diagnosis
Factor VIIa
Risk
Extracorporeal Membrane Oxygenation
Hemophilia A
Ischemic Attack, Transient
Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
Vertebrobasilar Insufficiency
Localized or diffuse reduction in blood flow through the vertebrobasilar arterial system, which supplies the BRAIN STEM; CEREBELLUM; OCCIPITAL LOBE; medial TEMPORAL LOBE; and THALAMUS. Characteristic clinical features include SYNCOPE; lightheadedness; visual disturbances; and VERTIGO. BRAIN STEM INFARCTIONS or other BRAIN INFARCTION may be associated.
Drug Therapy, Combination
Blood Coagulation Factors
Aspirin
The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
Ultrasonography, Doppler, Transcranial
A non-invasive technique using ultrasound for the measurement of cerebrovascular hemodynamics, particularly cerebral blood flow velocity and cerebral collateral flow. With a high-intensity, low-frequency pulse probe, the intracranial arteries may be studied transtemporally, transorbitally, or from below the foramen magnum.
Injury Severity Score
Immunoglobulins, Intravenous
Immunoglobulin preparations used in intravenous infusion, containing primarily IMMUNOGLOBULIN G. They are used to treat a variety of diseases associated with decreased or abnormal immunoglobulin levels including pediatric AIDS; primary HYPERGAMMAGLOBULINEMIA; SCID; CYTOMEGALOVIRUS infections in transplant recipients, LYMPHOCYTIC LEUKEMIA, CHRONIC; Kawasaki syndrome, infection in neonates, and IDIOPATHIC THROMBOCYTOPENIC PURPURA.
Plasminogen Activators
Gestational Age
Multicenter Studies as Topic
Predictive Value of Tests
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Myocardial Infarction
Embolism
Rupture, Spontaneous
Carotid Stenosis
Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)
Stents
Endarterectomy, Carotid
Carotid Artery, Internal
Multivariate Analysis
Detection of intracranial hemorrhage with susceptibility-weighted MR sequences. (1/639)
BACKGROUND AND PURPOSE: Detection of hemorrhage is important in the diagnosis and management of a variety of intracranial diseases. We evaluated the sensitivity of the following sequences for depicting chronic hemorrhagic foci associated with susceptibility dephasing: gradient-recalled echo (GRE) imaging, GRE-type single-shot echo-planar imaging (GRE-EPI), spin-echo-type single-shot echo-planar imaging (SE-EPI), turbo spin-echo (TSE) imaging, half-Fourier single-shot turbo spin-echo (HASTE) imaging, and segmented HASTE (s-HASTE) imaging. To our knowledge, no previous comparison has been made with these techniques in the same patient. METHODS: Fifty patients with suspected chronic hemorrhage were examined prospectively with the above six sequences. Contrast-to-noise ratio (CNR), sensitivity to detection of lesions, conspicuity of internal architecture, and sensitivity to small hemorrhagic foci were evaluated. RESULTS: Hemorrhagic foci were found in 35 patients. The CNR of the GRE, GRE-EPI, SE-EPI, TSE, s-HASTE, and HASTE sequences was 30.9, 23.7, 3.6, 6.1, -29.3, and -13.1, respectively; the number of small hemorrhagic foci detected was 85, 96, 44, 22, two, and one, respectively, for the supratentorial white matter; 70, 40, 19, four, zero, and zero, respectively, for the supratentorial cortical/subcortical region; and 73, 50, 26, 37, zero, and zero, respectively, for the infratentorial/skull-base region. CONCLUSION: The GRE sequence was best for detecting susceptibility dephasing associated with chronic intracranial hemorrhage. GRE-EPI, while comparable to GRE in the supratentorial compartment, was reduced in its sensitivity near the skull base, and may be used as an alternative to GRE in uncooperative, unsedated, pediatric, or claustrophobic patients. SE-EPI should not be used in screening for intracranial hemorrhage. (+info)Comparison of transcranial color-coded duplex sonography and cranial CT measurements for determining third ventricle midline shift in space-occupying stroke. (2/639)
BACKGROUND AND PURPOSE: Transcranial color-coded duplex sonography (TCCS) allows the noninvasive, easily reproducible measurement of midline dislocation (MLD) of the third ventricle in space-occupying stroke, even in critically ill patients. However, the method has been validated only in a small number of subjects. The aim of this study was to test the method under clinical conditions. METHODS: In 61 prospectively recruited patients (mean age, 62+/-15 years) with supratentorial ischemic infarction or intracranial hemorrhage, the sonographic measurement of MLD was compared with cranial CT data in a 12-hour time window. Subgroup analysis was also undertaken for comparing TCCS and cranial CT measurements within a 3-hour time window. RESULTS: One hundred twenty-two data pairs of TCCS and cranial CT MLD measurements were correlated within the 12-hour time window. TCCS and cranial CT measurements of MLD correlated both in the total patient group and in the different subgroups with coefficients of over 0.9. The 2-SD confidence interval of the difference between the TCCS measurements and the respective means of both methods in the total patient collective was +/-1.78 mm. CONCLUSION: TCCS provides a noninvasive, easily reproducible and reliable method for monitoring MLD of the third ventricle in stroke patients. It is particularly suitable for critically ill patients who are not fit for transportation. (+info)Predictors of clinical improvement, angiographic recanalization, and intracranial hemorrhage after intra-arterial thrombolysis for acute ischemic stroke. (3/639)
BACKGROUND AND PURPOSE: We sought to evaluate predictors of clinical outcome, angiographic success, and adverse effects after intra-arterial administration of urokinase for acute ischemic stroke. METHODS: We designed a Brain Attack program at University Hospitals of Cleveland for diagnosis and treatment of patients presenting within 6 hours of onset of neurological deficit. Patients with ischemia referable to the carotid circulation were treated with intra-arterial urokinase. Angiographic recanalization was assessed at the end of medication infusion. Intracerebral hemorrhage was investigated immediately after and 24 hours after treatment. Stroke severity was determined, followed by long-term outcome. RESULTS: Fifty-four patients were treated. There was improvement of >/=4 points on the National Institutes of Health Stroke Scale from presentation to 24 hours after onset in 43% of the treated patients, and this was related to the severity of the initial deficit. Forty-eight percent of patients had a Barthel Index score of 95 to 100 at 90 days, and total mortality was 24%. Cranial CT scans revealed intracerebral hemorrhage in 17% of patients in the first 24 hours, and these patients had more severe deficits at presentation. Eighty-seven percent of patients received intravenous heparin after thrombolysis, and 9% of them developed a hemorrhage into infarction. Angiographic recanalization was the rule in complete occlusions of the horizontal portion of the middle cerebral artery, but distal carotid occlusions responded less well to thrombolysis. CONCLUSIONS: The intra-arterial route for thrombolysis allows for greater diagnostic precision and achievement of a higher concentration of the thrombolytic agent in the vicinity of the clot. Disadvantages of this therapy lie in the cost and delay. Severity of stroke and site of angiographic occlusion may be important predictors of successful treatment. (+info)Cerebrovascular dynamics of autoregulation and hypoperfusion. An MRI study of CBF and changes in total and microvascular cerebral blood volume during hemorrhagic hypotension. (4/639)
BACKGROUND AND PURPOSE: To determine how cerebral blood flow (CBF), total and microvascular cerebral blood volume (CBV), and blood oxygenation level-dependent (BOLD) contrast change during autoregulation and hypotension using hemodynamic MRI. METHODS: Using arterial spin labeling and steady-state susceptibility contrast, we measured CBF and changes in both total and microvascular CBV during hemorrhagic hypotension in the rat (n=9). RESULTS: We observed CBF autoregulation for mean arterial blood pressure (MABP) between 50 and 140 mm Hg, at which average CBF was 1.27+/-0.44 mL. g(-1). min(-1) (mean+/-SD). During autoregulation, total and microvascular CBV changes were small and not significantly different from CBF changes. Consistent with this, no significant BOLD changes were observed. For MABP between 10 and 40 mm Hg, total CBV in the striatum increased slightly (+7+/-12%, P<0.05) whereas microvascular CBV decreased (-15+/-17%, P<0.01); on the cortical surface, total CBV increases were larger (+21+/-18%, P<0.01) and microvascular CBV was unchanged (3+/-22%, P>0.05). With severe hypotension, both total and microvascular CBV decreased significantly. Over the entire range of graded global hypoperfusion, there were increases in the CBV/CBF ratio. CONCLUSIONS: Parenchymal CBV changes are smaller than those of previous reports but are consistent with the small arteriolar fraction of total blood volume. Such measurements allow a framework for understanding effective compensatory vasodilation during autoregulation and volume-flow relationships during hypoperfusion. (+info)Neonatal focal temporal lobe or atrial wall haemorrhagic infarction. (5/639)
AIMS: To describe two variants of infarction within the temporal lobe, associated with local matrix bleeding and mild to moderate intraventricular haemorrhage. METHODS: The files of 10 neonates, extracted from a sonographic study of 560 very low birthweight infants conducted between 1993 and 1997, were retrospectively examined. RESULTS: Seven lesions were located in the middle to posterior area of the temporal lobe, three others faced the atrium. All except two of those with a temporal site were VLBW infants with hyaline membrane disease. Except for one fatal case, intraventricular bleeding was mild to moderate. Computed tomograms or magnetic resonance imaging were used to illustrate the haemorrhagic nature of three lesions. Survivors of this so far undescribed entity who were followed up for more than 18 months did not have a uniform type of cerebral palsy but some scored in the low normal range on the Bayley Mental Development Index. One girl developed temporal lobe epilepsy. CONCLUSIONS: This pattern of injury seems to be one of venous infarction associated with temporal or para-atrial matrix haemorrhage. The temporal site fits the picture of venous infarction within the area drained by the inferior ventricular vein. A less constant lateral atrial vein, either draining into the basal or internal cerebral vein, is probably involved in the para-atrial lesion. Sonography may be the only practical tool currently available for detection in life. (+info)Disseminated aspergillosis involving the brain: distribution and imaging characteristics. (6/639)
BACKGROUND AND PURPOSE: Systemic invasive aspergillosis involves the brain through hematogenous dissemination. A retrospective review of 18 patients with aspergillosis involving the brain was performed in order to present imaging findings and thereby broaden the understanding of the distribution and imaging characteristics of brain Aspergillus infection and to facilitate its early diagnosis. METHODS: The neuroimaging studies of 17 biopsy- or autopsy-proved cases and one clinically diagnosed case were examined retrospectively by two neuroradiologists. The studies were evaluated for anatomic distribution of lesions, signal characteristics of lesions, enhancement, hemorrhage, and progression on serial studies (when performed). Medical records, biopsy reports, and autopsy findings were reviewed. RESULTS: Thirteen of 18 patients had involvement of the basal nuclei and/or thalami. Nine of the 10 patients with lesions at the corticomedullary junction also had lesions in the basal nuclei or thalami. Callosal lesions were seen in seven patients. Progression of lesion number and size was seen in all 11 patients in whom serial studies had been performed. Enhancement was minimal or absent in most cases. There was gross hemorrhage in eight of the 18, and definite ring-enhancement in three. CONCLUSION: Among our cases, lesions in perforating artery territories were more common than those at the corticomedullary junction. Ring enhancement and gross hemorrhage may be present, but are not necessary for the prospective diagnosis. (+info)Level of in utero cocaine exposure and neonatal ultrasound findings. (7/639)
OBJECTIVE: To assess whether there is an association between the level of in utero cocaine exposure and findings on neonatal cranial ultrasound, controlling for potentially confounding variables. STUDY DESIGN: In a prospective longitudinal study, three cocaine exposure groups were defined by maternal report and infant meconium assay: unexposed, heavier cocaine exposure (>75th percentile self-reported days of use or of meconium benzoylecogonine concentration) or lighter cocaine exposure (all others). Neonatal ultrasounds from 241 well, term infants were read by a single radiologist who was masked to the exposure group. RESULTS: Infants with lighter cocaine exposure did not differ from the unexposed infants on any ultrasound findings. After controlling for infant gender, gestational age, and birth weight z scores and for maternal parity, blood pressure in labor, ethnicity, and use of cigarettes, alcohol, and marijuana during pregnancy, the more heavily cocaine-exposed infants were more likely than the unexposed infants to show subependymal hemorrhage in the caudothalamic groove (covariate adjusted odds ratio: 3.88; 95% confidence interval: 1.45, 10.35). CONCLUSIONS: This is the first study to demonstrate that ultrasound findings suggestive of vascular injury to the neonatal central nervous system are related to the level of prenatal cocaine exposure. Inconsistency in previous research in identifying an association between prenatal cocaine exposure and neonatal cranial ultrasound findings may reflect failure to consider dose effects. (+info)Incidence and occurrence of total (first-ever and recurrent) stroke. (8/639)
BACKGROUND AND PURPOSE: It has recently been hypothesized that the figure of approximately half a million strokes substantially underestimates the actual annual stroke burden for the United States. The majority of previously reported studies on the epidemiology of stroke used relatively small and homogeneous population-based stroke registries. This study was designed to estimate the occurrence, incidence, and characteristics of total (first-ever and recurrent) stroke by using a large administrative claims database representative of all 1995 US inpatient discharges. METHODS: We used the Nationwide Inpatient Sample of the Healthcare Cost and Utilization Project, release 4, which contains approximately 20% of all 1995 US inpatient discharges. Because the accuracy of International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM) coding is suboptimal, we performed a literature review of ICD-9-CM 430 to 438 validation studies. The pooled results from the literature review were used to make appropriate adjustments in the analysis to correct for some of the inaccuracies of the diagnostic codes. RESULTS: There were 682 000 occurrences of stroke with hospitalization (95% CI 660 000 to 704 000) and an estimated 68 000 occurrences of stroke without hospitalization. The overall incidence rate for occurrence of total stroke (first-ever and recurrent) was 259 per 100 000 population (age- and sex-adjusted to 1995 US population). Incidence rates increased exponentially with age and were consistently higher for males than for females. CONCLUSIONS: We conservatively estimate that there were 750 000 first-ever or recurrent strokes in the United States during 1995. This new figure emphasizes the importance of preventive measures for a disease that has identifiable and modifiable risk factors and for the development of new and improved treatment strategies and infrastructures that can reduce the consequences of stroke. (+info)
Differential Diagnosis of Spontaneous Intracranial Hemorrhage
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Tags: brain bleed, CVA, epidural hematoma, Intracranial Hemorrhage, stroke, subarachnoid hemorrhage, subdural hematoma, trauma ... Tags: brain bleed, CVA, epidural hematoma, Intracranial Hemorrhage, stroke, subarachnoid hemorrhage, subdural hematoma, trauma ... Tags: brain bleed, CVA, epidural hematoma, Intracranial Hemorrhage, stroke, subarachnoid hemorrhage, subdural hematoma, trauma ... Tags: brain bleed, CVA, epidural hematoma, Intracranial Hemorrhage, stroke, subarachnoid hemorrhage, subdural hematoma, trauma ...
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SYN: SEE: apoplexy; SEE: brain attack; SEE: cerebrovascular accident SEE: carotid endarterectomy; SEE: intracranial hemorrhage ... SYN: SEE: apoplexy; SEE: brain attack; SEE: cerebrovascular accident SEE: carotid endarterectomy; SEE: intracranial hemorrhage ... In the U.S., 80% of strokes are caused by cerebral infarct; intracranial hemorrhage and cerebral emboli are responsible for ... In the U.S., 80% of strokes are caused by cerebral infarct; intracranial hemorrhage and cerebral emboli are responsible for ...
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SubarachnoidIntraventricular hemorrhageIntraparenchymalCerebral hemorrhageNeonatesSubdural hematomaIncidenceSpontaneous intracerebral hemorrhageComputed tomographyHaemorrhageHypertensionVenousTraumaticPrognosisCases of intracranial hemorrhageOnset of intracranial hemorrhagePresence of intracranial hemorrhageDiagnosis of intracranial hemorrhageDevelopment of intracranial hemorrhageWarfarinIschemicPathophysiologyHematomasNeonatal Intracranial HemorrhageHypertensiveClinicalStrokeBleedsArteriovenous MalformationsKnown as intracranialImportant role in intracranialComplications2018Brain hemorrhageSkullNeurosurgeryEtiologyIntracerebral hemorrhage in patientsHeparinIntra-axial hemoIncrease in intracranial2020MethodsRiskAnticoagulationOccursReview intracranial hemorrhages2017Epidermoid cystInfants
Subarachnoid33
- Head CT shows crescent-shaped deformity Subarachnoid hemorrhage (SAH), which occur between the arachnoid and pia meningeal layers, like intraparenchymal hemorrhage, can result either from trauma or from ruptures of aneurysms or arteriovenous malformations. (wikipedia.org)
- The classic presentation of subarachnoid hemorrhage is the sudden onset of a severe headache (a thunderclap headache). (wikipedia.org)
- Hemorrhage within the meninges or the associated potential spaces, including epidural hematoma, subdural hematoma, and subarachnoid hemorrhage, is covered in detail in other articles. (medscape.com)
- Intracerebral hemorrhage is more likely to result in death or major disability than ischemic stroke or subarachnoid hemorrhage . (medscape.com)
- Heros RC et al Cerebral vasospasm after subarachnoid hemorrhage: an update. (springer.com)
- The larger autopsy-based studies report small subdural, subarachnoid, and intracerebral hemorrhages in 20-30% of live births. (medscape.com)
- These images show the system's ability to explain its diagnosis of subarachnoid (left above) and intraventricular (left below) hemorrhage by displaying images with similar appearances (right) from an atlas of images used to train the system. (gehealthcare.com)
- They included studies that provided outcomes for aspirin versus control in terms of risk for intracranial, subdural or extradural, intracerebral and subarachnoid hemorrhages. (naturalnews.com)
- It has increasingly been reported that intracranial hemorrhage, especially cortical subarachnoid bleeding, can accompany RCVS. (ahajournals.org)
- This is important because the most commonly understood reason for vasospasm or vasoconstriction in stroke is as a result of subarachnoid hemorrhage (usually, but not always, aneurysmal). (ahajournals.org)
- 9 A clinical presentation indistinguishable from RCVS has been documented in the context of aneurysmal subarachnoid hemorrhage. (ahajournals.org)
- Although this may be true, it also remains unclear how multifocal vasospasm could cause usually rather focal subarachnoid hemorrhage. (ahajournals.org)
- It is well described in the adult literature associated with subarachnoid hemorrhage where it is known as neurogenic stress cardiomyopathy (NSC), but few such pediatric cases have been reported. (biomedsearch.com)
- Subarachnoid hemorrhage (SAH) is a common and frequently life-threatening cerebrovascular disease, which is mostly related with a ruptured intracranial aneurysm. (degruyter.com)
- To date, AHA/ASA experts have consensus on the definition that stroke caused by subarachnoid hemorrhage only includes spontaneous SAH, which is mostly related with a ruptured intracranial aneurysm [ 1 , 2 , 7 , 8 ]. (degruyter.com)
- Subarachnoid hemorrhage is demonstrated. (sciencephoto.com)
- He died of subarachnoid hemorrhage the next day. (nih.gov)
- A brain hemorrhage, one of the two main types of stroke results when a ruptured artery causes bleeding into the brain (intracerebral bleed) or into the space between the membranes surrounding the brain (subarachnoid hemorrhage). (healthcommunities.com)
- Subarachnoid hemorrhages usually occur at the base of the brain and are usually due to rupture of cerebral aneurysms. (healthcommunities.com)
- Aneurysms (weak spots in the wall of an artery that may burst) are a major cause of subarachnoid hemorrhage. (healthcommunities.com)
- Subarachnoid hemorrhage was seen in the bilateral frontoparietal sulci, sylvian fissures, and the basilar and prepontine cisterns, with a small amount of intraventricular hemorrhage in the occipital horns of the lateral ventricles. (frontiersin.org)
- (B) Axial image from head CT demonstrating basilar traumatic subarachnoid hemorrhage. (frontiersin.org)
- Despite its favorable short-term outcome, concerns exist about long-term reopening and inherent risk of recurrent subarachnoid hemorrhage (SAH). (uva.nl)
- The authors report a case of recurrent subarachnoid hemorrhage (SAH) after complete occlusion of an intracranial aneurysm. (koreamed.org)
- Atrial and ventricular arrhythmias and various degrees of A-V block were reported in patients suffering from subarachnoid hemorrhage. (ahajournals.org)
- CT angiography (CTA) is increasingly used to assess for a vascular underlying cause, particularly in cases of subarachnoid hemorrhage, or intraparenchymal hemorrhage where something in the presentation, demographics of the patient or location/appearance of bleed make a primary hemorrhage less likely. (radiopaedia.org)
- In all, 56 patients (77%) had intraparenchymal hemorrhage, 22 patients (31%) had subdural hemorrhage, 15 patients (21%) had subarachnoid hemorrhage (SAH), and 3 patients (4%) had epidural hemorrhage. (biomedcentral.com)
- ICD-9 code 852.13 for Subarachnoid hemorrhage following injury with open intracranial wound with moderate (1-24 hours) loss of consciousness is a medical classification as listed by WHO under the range -INTRACRANIAL INJURY, EXCLUDING THOSE WITH SKULL FRACTURE (850-854). (aapc.com)
- MATERIAL AND METHODS: Intracerebral hematomas and subarachnoid hemorrhage were created by injecting autologous blood in 9 rabbits. (diva-portal.org)
- CONCLUSION: Susceptibility-weighted GRE imaging at 1.5 T is highly sensitive to both hyperacute hemorrhage in the brain parenchyma and to subarachnoid and intraventricular hemorrhage. (diva-portal.org)
- The goal in this study was to compare flat-panel detector (FD) CT with multislice (MS) CT in the visualization of intracerebral hemorrhage (ICH), subarachnoid hemorrhage (SAH), intraventricular hemorrhage, and external ventricular drains (EVDs) to evaluate the diagnostic quality and limitations of the new FD CT imaging modality. (thejns.org)
- Hoff, Julian T. 1999-11-01 00:00:00 AbstractOBJECTIVE:Anticoagulation-treated patients presenting with intracranial hemorrhage, including subdural hematoma, epidural hematoma, subarachnoid hemorrhage, and intracerebral hemorrhage, require urgent correction of their coagulopathy to prevent worsening hemorrhage and to facilitate surgical intervention when necessary. (deepdyve.com)
- Intracerebral bleeds are often misdiagnosed as subarachnoid hemorrhages due to the similarity in symptoms and signs. (wikipedia.org)
Intraventricular hemorrhage11
- This category includes intraparenchymal hemorrhage, or bleeding within the brain tissue, and intraventricular hemorrhage, bleeding within the brain's ventricles (particularly of premature infants). (wikipedia.org)
- Intracerebral hemorrhage (ICH) and extension of parenchymal bleeding into the ventricles (ie, intraventricular hemorrhage [IVH]) are detailed here. (medscape.com)
- Intraventricular hemorrhage occurs in one third of intracerebral hemorrhage cases from extension of thalamic ganglionic bleeding into the ventricular space. (medscape.com)
- Isolated intraventricular hemorrhage frequently arise from subependymal structures including the germinal matrix, AVMs, and cavernous angiomas. (medscape.com)
- Hallevi et al reviewed the charts and CT scans of patients with intraventricular hemorrhage (IVH) to determine if the extension of the hemorrhage could be measured. (medscape.com)
- Gross A et al Intraventricular hemorrhage originating from choroids plexues angioma in a road accident victim. (springer.com)
- More recent imaging-based studies show an inverse relationship between gestational age at birth and the incidence of intraventricular hemorrhage (IVH), ranging from 40-50% of neonates at less than 26 weeks' gestation to fewer than 5% of neonates at more than 32 weeks' gestation. (medscape.com)
- thus, germinal matrix hemorrhage (GMH) may result in intraventricular hemorrhage (IVH), intraparenchymal hemorrhage, or both. (medscape.com)
- Severe hypoxic-ischemic insults can cause intraventricular hemorrhage in full-term neonates. (millerandzois.com)
- Neonatal cerebrovascular accidents have classically been reported in the literature to bleeding events related to preterm birth, intraventricular hemorrhage being the most common variety in this age range [ 1 ]. (omicsonline.org)
- There is intraventricular hemorrhage noted with hemorrhage into the lateral ventricles, the third and the fourth ventricles. (sciencephoto.com)
Intraparenchymal7
- Intracranial hemorrhage is seen less frequently with dural than with intraparenchymal arteriovenous malformations (AVMs). (nih.gov)
- The most frequent type of intracranial hemorrhage was the intraparenchymal hemorrhage in 10/31 cases and bilateral hemispheric location was found in 14/31. (omicsonline.org)
- Intraparenchymal hemorrhage was the most common variety and lower psychomotor delay was observed until the time of the study in relation to the literature. (omicsonline.org)
- Intracranial Hemorrhage can occur spontaneously as a ruptured sacc ular aneurysm, Sub-Arachnoid Hemorrhage, Intraparenchymal Hemorrhage, or via trauma such as in an Epidural/Subdural Hematoma. (lasvegasemr.com)
- PURPOSE: To evaluate the MR appearance of intracranial, especially intraparenchymal, hemorrhage during the first 6 hours after bleeding with various pulse sequences in an animal model. (diva-portal.org)
- Intracerebral hemorrhage (ICH), also known as cerebral bleed and intraparenchymal bleed, is a sudden bleeding into the tissues of the brain, into its ventricles, or into both. (wikipedia.org)
- Intraparenchymal hemorrhage can be recognized on CT scans because blood appears brighter than other tissue and is separated from the inner table of the skull by brain tissue. (wikipedia.org)
Cerebral hemorrhage2
- Intra-axial hemorrhage is bleeding within the brain itself, or cerebral hemorrhage. (wikipedia.org)
- Multivariate analysis revealed three independent prognostic factors: prolonged prothrombin time ( P = 0.008), SAH ( P = 0.021), and multifocal cerebral hemorrhage ( P = 0.026). (biomedcentral.com)
Neonates9
- Dincsoy MY et al Intracranial hemorrhage in hypothalamic low-birth-weight neonates. (springer.com)
- A magnetic resonance imaging (MRI) study of full-term neonates found approximately a 25% incidence of asymptomatic intracranial hemorrhage after vaginal delivery. (medscape.com)
- Symptomatic intracranial hemorrhage in full-term neonates is much less common, in the range of 4 per 10,000 live births. (medscape.com)
- Intracranial hemorrhage in hypothermic low-birth-weight neonates. (nih.gov)
- We studied periventricular/intraventricular type intracranial hemorrhage (ICH) by cranial ultrasonography in 82 low-birth-weight (LBW) newborn infants with admission hypothermia against the gestational-age-matched 82 normothermic neonates. (nih.gov)
- Retrospective study of term neonates diagnosed of intracranial hemorrhage in the first 28 days of life in a third level hospital between January 2008 and December 2015. (omicsonline.org)
- The aim of the study was to determine the incidence of intracranial hemorrhage and other major bleeds in neonates with moderate and severe hemophilia in relationship to mode of delivery and known family history. (haematologica.org)
- Intracranial hemorrhage of term neonates with severe von Willebrand disease type 3 and near normal delivery have not been published to date. (haematologica.org)
- METHODS: A total of 374 neonates with suspected intracranial hemorrhage from January 2017 to December 2019 were selected to be primarily screened by cranial ultrasonography and then diagnosed by cranial CT scan. (minervamedica.it)
Subdural hematoma1
- Two cases of spinal epidural hematoma and two cases of intracranial subdural hematoma after lumbar puncture (LP) are reported in children receiving chemotherapy for acute lymphoblastic leukemia and non-Hodgkin lymphoma. (nih.gov)
Incidence12
- The overall incidence of intracerebral hemorrhage has declined since the 1950s. (medscape.com)
- Asian countries have a higher incidence of intracerebral hemorrhage than other regions of the world. (medscape.com)
- Intracerebral hemorrhage has a higher incidence among populations with a higher frequency of hypertension, including African Americans. (medscape.com)
- A higher incidence of intracerebral hemorrhage has been noted in Chinese, Japanese, and other Asian populations, possibly due to environmental factors (eg, a diet rich in fish oils) and/or genetic factors. (medscape.com)
- The true incidence of perinatal intracranial hemorrhage is not known. (medscape.com)
- Intracranial hemorrhage is an uncommon but important cause of morbidity and mortality in term newborns of unknown incidence. (omicsonline.org)
- The study's main outcome was the incidence rate ratios (RRs) of intracranial hemorrhage stratified by current use of SSRIs vs. TCAs as well as strong vs. weak serotonin reuptake inhibitors. (empr.com)
- There were no differences observed in the cumulative incidence of intracranial hemorrhage at 1 year in the enoxaparin and control cohorts for measurable (19% vs 21%, Gray test P=0.97, HR 1.02 [90%CI 0.66-1.59]), significant (21% vs 22%, P=0.87), and total (44% vs 37%, P=0.13) intracranial hemorrhages. (bloodjournal.org)
- Objectives The study defined the incidence of cerebral hyperperfusion syndrome and intracranial hemorrhage (ICH) and the risk factors for their development following carotid artery stenting (CAS). (onlinejacc.org)
- Incidence and Prognostic Impact of Intracranial Hemorrhage after Endovascular Treatment for Acute Large Vessel Occlusion. (physiciansweekly.com)
- CONCLUSIONS: Neonatal intracranial hemorrhage can be well diagnosed by cranial ultrasonography which timely provides evidence for clinicians, thereby elevating the cure rate and reducing the mortality rate and incidence rate of sequelae. (minervamedica.it)
- Intracranial hemorrhage in association with thrombolytic therapy: incidence and clinical predictive factors. (semanticscholar.org)
Spontaneous intracerebral hemorrhage4
- All patients had spontaneous intracerebral hemorrhage. (medicalnewstoday.com)
- Guidelines for the management of spontaneous intracerebral hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. (medscape.com)
- Guidelines for the management of spontaneous intracerebral hemorrhage in adults: 2007 update: a guideline from the American Heart Association/American Stroke Association Stroke Council, High Blood Pressure Research Council, and the Quality of Care and Outcomes in Research Interdisciplinary Working Group. (medscape.com)
- High blood pressure raises the risks of spontaneous intracerebral hemorrhage by two to six times. (wikipedia.org)
Computed tomography8
- CT scan (computed tomography) is the definitive tool for accurate diagnosis of an intracranial hemorrhage. (wikipedia.org)
- Sensitivity of computed tomography for sub-arachnoid hemorrhage. (springer.com)
- TUESDAY, Oct. 22, 2019 (HealthDay News) - A deep learning algorithm has accuracy comparable to that of radiologists for the diagnosis of acute intracranial hemorrhage on head computed tomography (CT), according to a study published online Oct. 21 in the Proceedings of the National Academy of Sciences . (physiciansweekly.com)
- In this study, we compared the use of fresh frozen plasma (FFP) with that of Factor IX complex concentrate (FIXCC) to achieve rapid correction of warfarin anticoagulationMETHODS:Patients admitted to a tertiary care center with computed tomography-proven intracranial hemorrhage and a prothrombin time of more than 17 seconds were considered for inclusion in the study protocol. (deepdyve.com)
- METFIODS: Patients admitted to a tertiary care center with computed tomography-proven intracranial hemorrhage and a prothrombin time of more than 17 seconds were considered for inclusion in the study protocol. (deepdyve.com)
- Computed tomography revealed right-sided putamen hemorrhage (Fig. 1, Panel A). The patient had no risk factors for intracranial hemorrhage, including hypertension, older age, alcohol intake, and dyslipidemia. (efim.org)
- We propose a novel method that combines a convolutional neural network (CNN) with a long short-term memory (LSTM) mechanism for accurate prediction of intracranial hemorrhage on computed tomography (CT) scans. (arxiv.org)
- citation needed] Both computed tomography angiography (CTA) and magnetic resonance angiography (MRA) have been proved to be effective in diagnosing intracranial vascular malformations after ICH. (wikipedia.org)
Haemorrhage2
- Intracranial haemorrhage is a devastating cause of stroke.The theoretical rationale for lowering blood pressure is to decrease the risk of ongoing bleeding from ruptured small arteries and arterioles.Thank you for such a well written article. (lasvegasemr.com)
- The market for global intracranial haemorrhage treatment is chiefly driven by factors such as rising cases of trauma, accidents, age related brain disorders, cancer etc. (medgadget.com)
Hypertension5
- More than half of all cases of intracranial hemorrhage is the result of hypertension. (wikipedia.org)
- To alleviate the increased intracranial pressure associated with intracranial hypertension (pseudotumor cerebri), a lumbar puncture is used to reduce the volume of CSF. (medscape.com)
- 3,4 Factors that influence hematoma evolution include location (intra- or extra-axial, gray versus white matter), size (punctuate versus confluent, unifocal versus multifocal), etiology (arterial versus venous, trauma versus hypertension), and temporal occurrence of hemorrhage (acute event versus multistaged, recurrent hemorrhage). (diagnosticimaging.com)
- 1. "Traumatic Intracranial Hypertension. (lasvegasemr.com)
- Isovolume hypertonic solutes (sodium chloride or mannitol) in the treatment of refractory posttraumatic intracranial hypertension: 2 mL/kg 7.5% saline is more effective than 2 mL/kg 20% mannitol. (lasvegasemr.com)
Venous3
- Although hemorrhage was relatively infrequent (7.5%) with dural AVMs located primarily within a major venous sinus, bleeding episodes occurred in 20 of the 39 (51%) cases of malformation outside a major sinus. (nih.gov)
- We report on a term newborn with severe type 3 VWD who suffered a large intracranial bleeding presumably subsequent to sinus venous thrombosis. (haematologica.org)
- There are two types of in intracranial hemorrhaging: arterial bleeding, in which there is loss of oxygen to the issues that carry blood to the heart, and venous bleeding, a hemorrhage that affects the veins that are responsible for returning blood to the heart. (birthinjuryguide.org)
Traumatic11
- Nonpenetrating and penetrating cranial trauma are also common causes of intracerebral hemorrhage.Patients who experience blunt head trauma and subsequently receive warfarin or clopidogrel are considered at increased risk for traumatic intracranial hemorrhage. (medscape.com)
- According to one study, patients receiving clopidogrel have a significantly higher prevalence of immediate traumatic intracranial hemorrhage compared with patients receiving warfarin. (medscape.com)
- Delayed traumatic intracranial hemorrhage is rare and occurred only in patients receiving warfarin. (medscape.com)
- Sodium lactate versus mannitol in the treatment of intracranial hypertensive episodes in severe traumatic brain-injured patients. (lasvegasemr.com)
- Detailed cerebrovascular imaging can evaluate the relationship of intracranial foreign bodies to major vascular structures, assess for traumatic pseudoaneurysms, and ensure hemostasis during surgical removal. (frontiersin.org)
- Weicheng Kuo, Ph.D., from the University of California Berkeley, and colleagues trained a fully convolutional neural network to detect neurologic emergencies (e.g., traumatic brain injury, stroke, and aneurysmal hemorrhage) utilizing 4,396 head CT scans performed at the University of California at San Francisco and affiliated hospitals. (physiciansweekly.com)
- Characterizing the type and location of intracranial abnormalities in mild traumatic brain injury. (annals.org)
- Intracranial Hemorrhage, Traumatic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
- This graph shows the total number of publications written about "Intracranial Hemorrhage, Traumatic" by people in this website by year, and whether "Intracranial Hemorrhage, Traumatic" was a major or minor topic of these publications. (umassmed.edu)
- Below are the most recent publications written about "Intracranial Hemorrhage, Traumatic" by people in Profiles. (umassmed.edu)
- From December 2016 to March 2018, we reviewed daily reports of all admissions with primary diagnosis of any non-traumatic sub-arachnoid hemorrhage (NT-SAH) in our institute which is an academic tertiary center with full service neurosurgery and INR team. (cns.org)
Prognosis2
- Intracranial hemorrhage : Diagnosis, prognosis, acute treatment and secondary prophylaxis. (biomedsearch.com)
- The aim of this study is to analyze the etiological factors, evolution and neurological prognosis of term new-borns affected by intracranial hemorrhage and epidemiological data associated with our series, in order to understand better the clinical characteristics of these patients and avoid prolonged diagnosis. (omicsonline.org)
Cases of intracranial hemorrhage3
- We report 6 cases of intracranial hemorrhage among our past 10 patients with dural AVMs. (nih.gov)
- A literature search provided 27 other cases of intracranial hemorrhage from a total of 213 reported dural AVMs. (nih.gov)
- A total of 3,036 cases of intracranial hemorrhage were identified during the follow-up period and were matched to 89,702 controls. (empr.com)
Onset of intracranial hemorrhage2
- It is suggested that the initiation of therapy with autonomic blocking drugs, as soon as possible after the onset of intracranial hemorrhage in patients, may be useful in preventing myocardial damage and cardiac arrhythmias. (ahajournals.org)
- The partial thromboplastin time (PTT) was excessively prolonged (from 81 s to more than 150 s) in all patients at onset of intracranial hemorrhage. (annals.org)
Presence of intracranial hemorrhage2
- No difference in neurological outcomes was detected between groups, but a higher complication rate was observed for the FFP-treated group.CONCLUSION:The use of FIXCC accelerated correction of warfarin-related anticoagulation in the presence of intracranial hemorrhage. (deepdyve.com)
- Here we present an unusual case of papillary neuroepithelial tumor of the pineal region in a 40-year-old man who was admitted in a state of unconsciousness due to the presence of intracranial hemorrhage. (minervamedica.it)
Diagnosis of intracranial hemorrhage1
- the mean time of diagnosis of intracranial hemorrhage was 2.2 days from headache onset and the mean time to diagnosis of vasoconstriction was 6.6 days. (ahajournals.org)
Development of intracranial hemorrhage2
- Studies have identified many risk factors for the development of intracranial hemorrhage in preterm infants, such as low gestational age (LGA) and birth weight, maternal chorioamnionitis and other infections or inflammation, lack of antenatal steroid exposure, hypotension, hypoxemia, hypercapnia, pneumothorax, respiratory distress syndrome, and many others. (medscape.com)
- In our series hypoxia and/or dystocia were the factors most frequently associated with the development of intracranial hemorrhage and seizures, apnea and anemia were the more common signs of presentation. (omicsonline.org)
Warfarin3
- HOUSTON, TX-There's no such thing as a good intracranial hemorrhage (ICH), but a new analysis hints that patients who have one might be better off if they're taking a non-vitamin K antagonist oral anticoagulant (NOAC) rather than warfarin at the time. (tctmd.com)
- Nevertheless, "it at least suggests that the [NOAC-related] hemorrhages are no more severe and may be actually less severe than warfarin-related hemorrhages," he continued. (tctmd.com)
- Use of Factor IX Complex in Warfarin-related Intracranial Hemorrhage Boulis, Nicholas M. (deepdyve.com)
Ischemic2
- Intracranial hemorrhage (ICH) accounts for 10% to 15% of all strokes and has higher rates of morbidity and mortality than do ischemic strokes of similar volume ( 1 ). (ajnr.org)
- Intracerebral hemorrhage, a type of hemorrhagic stroke, was first distinguished from ischemic strokes due to insufficient blood flow, so called "leaks and plugs", in 1823. (wikipedia.org)
Pathophysiology2
- Xi G et al Intracerebral hemorrhage, pathophysiology and therapy. (springer.com)
- Auer RN, Sutherland GR. Primary intracerebral hemorrhage: pathophysiology. (medscape.com)
Hematomas3
- The timely recognition of hemorrhages, particularly of extracerebral hematomas, accompanying head injuries is a matter of life and death for the patient. (springer.com)
- Intracranial hematomas follow well-described, predictable pathophysiological processes of evolution and resorption (Figures 1 and 2). (diagnosticimaging.com)
- The intracerebral hematomas were predominantly of lobar location, and two patients had multiple simultaneous hemorrhages. (annals.org)
Neonatal Intracranial Hemorrhage4
- Neonatal Intracranial Hemorrhage (ICH) (sometimes called a "brain bleed") is a bleeding inside the brain of the newborn. (millerandzois.com)
- We aimed to explore the feasibility and accuracy of three-dimensional (3D) ultrasonography for the quantitative evaluation of neonatal intracranial hemorrhage. (minervamedica.it)
- 3D ultrasonography is feasible and accurate for the quantitative evaluation of neonatal intracranial hemorrhage, thus being of great significance to prognostic determination in clinical practice. (minervamedica.it)
- Li X, Zhao F, Bai X, Wang X. Application value of cranial ultrasonography in quantitative evaluation of neonatal intracranial hemorrhage. (minervamedica.it)
Hypertensive3
- Each year, intracerebral hemorrhage affects approximately 12-15 per 100,000 individuals, including 350 hypertensive hemorrhages per 100,000 elderly individuals. (medscape.com)
- The 2010 AHA/ASA guidelines for spontaneous ICH recommend that after acute intracerebral hemorrhage, patients without medical contraindications should have BP well controlled, especially for hemorrhage in typical hypertensive vasculopathy locations. (medscape.com)
- Intracranial hemorrhage in the hypertensive patient. (medscape.com)
Clinical13
- All intracranial hemorrhages (ICH) share some classic clinical features. (saem.org)
- December 6, 2018 -- An artificial intelligence (AI) algorithm can detect all types of intracranial hemorrhage (ICH) on noncontrast head CT studies, showing potential for use in all clinical scenarios that involve detecting and tracking this critical condition, according to research presented at the recent RSNA 2018 meeting in Chicago. (auntminnie.com)
- Intracranial hemorrhage complicating acute stroke: how common is hemorrhagic stroke on initial head CT scan and how often is initial clinical diagnosis of acute stroke eventually confirmed? (medscape.com)
- In particular, the team looked at randomized clinical trials that compared low-dose aspirin with a control and recorded the endpoints of intracranial hemorrhage separately for the two groups. (naturalnews.com)
- Each case was analyzed in relation to gestational age, obstetric history and type and instrumentalization of delivery and we have also recorded the clinical, analytical data and neuroimaging test performed, which is the basis for diagnosis and classification according to the location of intracranial hemorrhage. (omicsonline.org)
- We report here clinical and neuroimaging findings from a patient with an intracranial nail gun injury, a communicating ventricular tract hemorrhage upon nail removal, and a delayed pseudoaneurysm, whose treatment was augmented with neuroendovascular techniques. (frontiersin.org)
- This preliminary effort should generate meaningful clinical prognostic indicators for moderate size hemorrhages in large scale studies. (ajnr.org)
- The researchers found that the algorithm demonstrated the highest accuracy to date for this clinical application, with a receiver operating characteristic area under the curve of 0.991 for identification of acute intracranial hemorrhage. (physiciansweekly.com)
- Clinical characteristics and outcomes of intracranial hemorrhage (ICH) among adult patients with various hematological malignancies are limited. (biomedcentral.com)
- International Classification of Disease, Ninth Revision, Clinical Modification codes were used to identify index cases of ICH, intracranial procedures, and comorbidities. (ovid.com)
- What are the clinical characteristics of patients treated with rivaroxaban for stroke prevention in atrial fibrillation (AF), who experienced intracranial hemorrhage (ICH) events? (acc.org)
- The median time interval between the start of thrombolytic therapy and the first clinical signs of intracranial bleeding was 16 h (range 3 to 36). (semanticscholar.org)
- 3 The Intracranial Hemorrhage or Cerebral Infarction episode-based cost measure was recommended for development by an expert clinician committee-the Neuropsychiatric Disease Management Clinical Subcommittee-because of its high impact in terms of patient population and Medicare spending, and the opportunity for incentivizing cost-effective, highquality clinical care in this area. (mdinteractive.com)
Stroke4
- What are the AHA/ASA treatment guidelines for spontaneous intracranial hemorrhage (ICH) in hemorrhagic stroke? (medscape.com)
- Rapid recognition of intracranial hemorrhage, leading to prompt appropriate treatment of patients with acute stroke symptoms, can prevent or mitigate major disability or death," says co-author Michael Lev, MD, MGH Radiology. (gehealthcare.com)
- Effects of hypertonic saline hydroxyethyl starch solution and mannitol in patients with increased intracranial pressure after stroke. (lasvegasemr.com)
- A prospective cohort study showed that those with NOAC-related hemorrhages presented with a smaller hematoma volume, less severe stroke symptoms, and a lower rate of severe ICH than did patients who were taking a vitamin K antagonist (VKA), Georgios Tsivgoulis, MD, PhD (University of Athens, Greece), reported at the International Stroke Conference held here last week. (tctmd.com)
Bleeds7
- Intra-axial hemorrhages are more dangerous and harder to treat than extra-axial bleeds. (wikipedia.org)
- How are brain bleeds (intracranial hemorrhage) diagnosed? (clevelandclinic.org)
- What Is Brain Hemorrhage (Intracranial Bleeds)? (healthcommunities.com)
- Twenty intracranial hemorrhages (2.2%) and 44 other major bleeds (4.8%) occurred. (haematologica.org)
- There was no significant difference in frequency for intracranial hemorrhages and major bleeds between a planned Cesarean section and a planned vaginal delivery. (haematologica.org)
- Children with a family history of hemophilia (n=466) were more likely to be born by Cesarean section (35.8% vs . 27.6%), but no difference in the rate of intracranial hemorrhages or major bleeds was found. (haematologica.org)
- A carrier may have an increased bleeding risk herself that might need to be taken into account in the obstetric planning but, from the fetal point of view, the key question is how the mode of delivery may impact on the risk of major bleeds, and in particular intracranial hemorrhages (ICH). (haematologica.org)
Arteriovenous Malformations1
- Less common causes of intracranial hemorrhage are bleeding disorders (particularly those that require blood-thinning medication) and abnormal arteries or veins (arteriovenous malformations). (dignityhealth.org)
Known as intracranial1
- Intracranial hemorrhage (ICH), also known as intracranial bleed, is bleeding within the skull. (wikipedia.org)
Important role in intracranial2
- From previous studies, we know that dysregulation of autonomic system plays an important role in intracranial hemorrhage. (clinicaltrials.gov)
- Non-coding RNAs (ncRNAs), comprising of microRNAs (miRNAs), small interfering RNAs (siRNAs) and long non-coding RNAs (lncRNAs), play an important role in intracranial aneurysms and SAH. (degruyter.com)
Complications2
- Hemorrhage itself is associated with sympathoexcitation, and patients who develop rebleeding or infarction complications are found to have an even higher degree of sympathetic storm. (clinicaltrials.gov)
- This manuscript reports Bacillus cereus sepsis in two cases with acute myelogenous leukemia (AML) who suffered complications of fatal intracranial hemorrhage during remission induction therapy. (nih.gov)
20181
- Worldwide Intracranial Hemorrhage Diagnosis and Treatment Market 2018 provide past and estimate future revenue of the market's segments and sub-segments with respect to four main geographies and their countries - Americas, Europe, Asia-Pacific along with Middle East & Africa. (medgadget.com)
Brain hemorrhage7
- A doctor will examine you immediately if any type of brain hemorrhage is suspected. (clevelandclinic.org)
- Arizona's finest neurological care is available at Dignity Health, including for brain hemorrhage, throughout Arizona. (dignityhealth.org)
- Bleeding in or around the brain is classified further as cerebral (brain) hemorrhage. (dignityhealth.org)
- What Causes Brain Hemorrhage? (healthcommunities.com)
- An increasingly recognized cause of brain hemorrhage in the elderly is amyloid angiopathy. (healthcommunities.com)
- Call an ambulance if you develop symptoms of a brain hemorrhage. (healthcommunities.com)
- Brain hemorrhage is a medical EMERGENCY Call an ambulance immediately. (healthcommunities.com)
Skull10
- Intracranial hemorrhage is a serious medical emergency because the buildup of blood within the skull can lead to increases in intracranial pressure, which can crush delicate brain tissue or limit its blood supply. (wikipedia.org)
- Severe increases in intracranial pressure (ICP) can cause brain herniation, in which parts of the brain are squeezed past structures in the skull. (wikipedia.org)
- Intracranial bleeding occurs when a blood vessel within the skull is ruptured or leaks. (wikipedia.org)
- Extra-axial hemorrhage, bleeding that occurs within the skull but outside of the brain tissue, falls into three subtypes: Epidural hemorrhage (extradural hemorrhage) which occur between the dura mater (the outermost meninx) and the skull, is caused by trauma. (wikipedia.org)
- From healthline.com: "Intracranial hemorrhage (ICH) refers to acute bleeding inside your skull or brain. (infowars.com)
- A patient's blood pressure can rapidly increase due to intracranial hemorrhage (bleeding within the skull). (medicalnewstoday.com)
- An intracranial hemorrhage is bleeding inside the skull (cranium). (dignityhealth.org)
- An intracranial hemorrhage occurs when an artery inside the skull leaks or ruptures. (dignityhealth.org)
- The model was neither sensitive nor specific for atraumatic brain abnormalities, isolated skull fractures, or chronic intracranial hemorrhage. (luriechildrens.org)
- The following list attempts to classify Other closed skull fracture with other and unspecified intracranial hemorrhage, with prolonged [more than 24 hours] loss of consciousness and return to pre-existing conscious level into categories where each line is subset of the next. (rightdiagnosis.com)
Neurosurgery1
- Spontaneous intracranial hemorrhage is an absolute emergency in the field of neurosurgery, and it is also a devastating event that commonly results in major neurological disabilities or mortalities. (clinicaltrials.gov)
Etiology2
- The etiology of intracranial hemorrhage in infants varies according to the location of the hemorrhage and the gestational age of the infant. (medscape.com)
- Alternatively, intracranial hemorrhage can be thought of in terms of the underlying cause, although in most cases the same etiology can result in multiple different patterns of hemorrhage. (radiopaedia.org)
Intracerebral hemorrhage in patients2
- Given the number of studies that have investigated the subject of intracerebral hemorrhage, there are still many research questions unanswered, including prevention and treatment of progressive hemorrhage, indications for surgical intervention, secondary prophylaxis and also treatment of intracerebral hemorrhage in patients with new anticoagulants. (biomedsearch.com)
- Amyloid angiopathy is a not uncommon cause of intracerebral hemorrhage in patients over the age of 55. (wikipedia.org)
Heparin3
- To assess the risk of intracranial hemorrhage associated with the administration of therapeutic doses of low molecular heparin, we performed a matched, retrospective cohort study of 293 cancer patients with brain metastasis (104 with therapeutic enoxaparin and 189 controls). (bloodjournal.org)
- intracranial hemorrhage occurred between 2 and 14 hours after tPA infusion ended and between 3 and 17 hours after heparin therapy was started. (annals.org)
- Factors possibly related to hemorrhage include a systemic fibrinolytic state or a platelet anti-aggregant effect produced by tPA and enhanced hemorrhagic tendency caused by the combined effects of tPA and heparin. (annals.org)
Intra-axial hemo1
- Vasogenic edema may develop within adjacent brain tissue in the case of an intra-axial hemorrhage. (diagnosticimaging.com)
Increase in intracranial1
- SSRIs have been previously linked to an increase in intracranial hemorrhage, however, whether antidepressants that are strong inhibitors of serotonin reuptake actually raise the risk for intracranial hemorrhage is still unknown. (empr.com)
20202
- The 8th World IntraCranial Hemorrhage Conference (WICH 2020) is dedicated to significant new developments and scientific advancements in the field of intracranial hemorrhage. (clocate.com)
- The 8th World IntraCranial Hemorrhage Conference (WICH 2020) might be held in May 2020 (Not Final). (clocate.com)
Methods1
- Ultrasound, CT, MRI, and DSA are well-established sensitive methods of identifying and evaluating intracranial hemorrhages. (diagnosticimaging.com)
Risk37
- Anticoagulant therapy, as well as disorders with blood clotting can heighten the risk that an intracranial hemorrhage will occur. (wikipedia.org)
- The results showed that compared with patients taking [the older] tricyclic antidepressants, patients being treated with SSRIs had a 17 percent increased risk of experiencing an intracranial hemorrhage. (infowars.com)
- Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a life-threatening disease in which intracranial hemorrhage (ICH) is the major risk. (jci.org)
- Patients with glioma receiving therapeutic anticoagulation had a greater than threefold risk for intracranial hemorrhage, according to the results of a meta-analysis. (healio.com)
- However, patients receiving anticoagulation for brain metastases did not have an increased intracranial hemorrhage risk, results showed. (healio.com)
- However, the routine use of anticoagulation remains controversial due to the increased risk for intracranial hemorrhage in patients with brain tumors. (healio.com)
- Jeffrey I. Zwicker, MD, associate professor of medicine at Harvard Medical School and member of the developmental therapeutics unit at Beth Israel Deaconess Medical Center, and colleagues conducted a meta-analysis of nine retrospective cohort studies to determine whether therapeutic anticoagulation was associated with an increased risk for intracranial hemorrhage in this patient population. (healio.com)
- While anticoagulation may increase the risk for intracranial hemorrhage in patients with glioma, higher quality studies are required in order to better evaluate the absolute increased risk associated with therapeutic anticoagulation," Zwicker and colleagues wrote. (healio.com)
- Natural News ) Taking aspirin could potentially increase the risk of intracranial hemorrhage, even among people without symptomatic cardiovascular disease. (naturalnews.com)
- For the review, the team investigated the link between low-dose aspirin use and intracranial hemorrhage risk. (naturalnews.com)
- They used a 95-percent confidence interval for relative risk as a measure of aspirin vs control on risk of intracranial hemorrhage. (naturalnews.com)
- Based on data from the random-effect estimate, low-dose aspirin was linked to an increased risk of any intracranial bleeding. (naturalnews.com)
- The greatest relative risk increase that the researchers identified was for subdural or extradural hemorrhage. (naturalnews.com)
- In sum, low-dose aspirin was linked to an overall increased risk of intracranial hemorrhages. (naturalnews.com)
- As the use of vitamin K antagonists is increased, the risk of anticoagulant-related intracranial hemorrhage(ICH) is emphasized. (ersjournals.com)
- This large series (for a fairly rare condition) allowed the authors not only to describe the patterns of bleeding but also to investigate the risk factors for hemorrhage in RCVS. (ahajournals.org)
- Indeed, patients with Alzheimer's disease are at greater risk for amyloidrelated brain hemorrhages. (healthcommunities.com)
- There has been a potentially increased risk of intracranial hemorrhage (ICH) in patients receiving bevacizumab. (virtualtrials.com)
- For detection of recurrence, however, it may be necessary to follow up with the patient regularly after the initial operation for intracranial aneurysms, because re-rupture of an aneurysm can cause a fatal result, and the cumulative risk of a recurrent SAH is thought to be not low over time. (koreamed.org)
- A new study published in JAMA Neurology reports that treatment with selective serotonin reuptake inhibitors (SSRIs) and antidepressants in general with strong inhibition of serotonin reuptake is associated with a greater risk of intracranial hemorrhage. (empr.com)
- Researchers from the Jewish General Hospital and McGill University set out to evaluate the risk for intracranial hemorrhage with the use of SSRIs vs. tricyclic antidepressants (TCAs) among new users. (empr.com)
- The study found that current SSRI use was associated with a higher risk for intracranial hemorrhage (RR 1.17, 95% CI: 1.02-1.35) vs. TCAs, with highest risk during the first 30 days of use (RR 1.44, 95% CI: 1.04-1.99). (empr.com)
- The risk for intracranial hemorrhage was 25% higher with the use of strong inhibitors (RR 1.25, 95% CI: 1.01-1.54) and was at the highest during the first 30 days of use (RR 1.68, 95% CI: 0.90-3.12). (empr.com)
- Therapeutic anticoagulation in patients with brain metastasis did not increase the risk of intracranial hemorrhage. (bloodjournal.org)
- We conclude that intracranial hemorrhage is frequently observed in patients with brain metastases but that therapeutic anticoagulation does not increase the risk of intracranial hemorrhage. (bloodjournal.org)
- carry] a lower risk of having an intracranial hemorrhage. (tctmd.com)
- One is lower risk of having a hemorrhage in the first place, and secondly, there's at least a suggestion that the outcome if you do have one may not be as bad. (tctmd.com)
- When pooling results with two other studies, the investigators showed that NOAC-related hemorrhages had smaller volumes at admission, carried a lower risk of in-hospital mortality, and tended to result in a lower rate of hematoma expansion. (tctmd.com)
- Such therapy may increase the risk of hemorrhage in patients who require concurrent external ventricular drainage and/or subsequent permanent cerebrospinal fluid diversion. (thejns.org)
- The necessity of dual antiplatelet therapy in the use of stent-assisted coil embolization increases the risk of intracranial hemorrhage and possibly rebleeding from a ruptured aneurysm. (thejns.org)
- Main Outcomes and Measures: A mathematical model that can predict acute intracranial hemorrhage in infants at increased risk of abusive head trauma. (luriechildrens.org)
- What is the performance of novel oral anticoagulants (NOACs) in reducing risk of intracranial hemorrhage (ICH)? (acc.org)
- To assess the possible risk factors associated with in-hospital death and symptomatic intracerebral hemorrhage among patients who received intravenous tissue plasminogen activator. (cdc.gov)
- HealthDay News -- Of more than four million people prescribed a first-time antidepressant , those who also used nonsteroidal anti-inflammatory drugs (NSAIDs) had a higher risk of intracranial hemorrhage within the next month, according to a report published in The BMJ . (clinicalpainadvisor.com)
- Byung-Joo Park, MD, PhD, MPH, a professor of preventive medicine at the Seoul National University College of Medicine in South Korea, and colleagues looked at whether the two drug types , used together, might increase the risk of intracranial hemorrhage. (clinicalpainadvisor.com)
- Park also pointed out that the study looked at the risk of intracranial hemorrhage within 30 days. (clinicalpainadvisor.com)
- The Intracranial Hemorrhage or Cerebral Infarction episode-based cost measure evaluates a clinician's risk-adjusted cost to Medicare for beneficiaries who receive inpatient treatment for cerebral infarction or intracranial hemorrhage during the performance period. (mdinteractive.com)
Anticoagulation1
- The question of whether there is a difference in terms of the severity of those hemorrhages based on the type of anticoagulation remains open, he said. (tctmd.com)
Occurs3
- Most bevacizumab-related ICH occurs into central nervous system tumors but spontaneous hemorrhages were seen. (virtualtrials.com)
- Significant intracranial hemorrhage occurs in 20-50% of patients with metastatic brain tumors. (bloodjournal.org)
- If a hemorrhage occurs in the brain in infants before, during, or shortly after birth, several parts of the brain that are important for development and motor skills can become impaired. (birthinjuryguide.org)
Review intracranial hemorrhages1
- This article will review intracranial hemorrhages that may occur in the perinatal period. (medscape.com)
20171
- Considering all these factors the market for intracranial hemorrhage diagnosis and treatment is expected to reach $ 1.9 billion by the end of 2023, this market is projected to growing at a CAGR of ~ 6.1 % during 2017-2023. (medgadget.com)
Epidermoid cyst1
- Hemorrhage in intracranial epidermoid cyst. (ajnr.org)
Infants4
- In preterm infants of less than 32 weeks' gestation, the most common source of intracranial hemorrhage is the germinal matrix. (medscape.com)
- Objective: To identify and validate a set of biomarkers that could be the basis of a multivariable model to identify intracranial hemorrhage in well-appearing infants using the Ziplex System. (luriechildrens.org)
- Conclusion and Relevance: The Biomarkers for Infant Brain Injury Score, a multivariable model using 3 serum biomarker concentrations and serum hemoglobin, can identify infants with acute intracranial hemorrhage. (luriechildrens.org)
- Accurate and timely identification of intracranial hemorrhage in infants without a history of trauma in whom trauma may not be part of the differential diagnosis has the potential to decrease morbidity and mortality from abusive head trauma. (luriechildrens.org)