Intracranial Embolism and Thrombosis
Blockage of an artery due to passage of a clot (THROMBUS) from a systemic vein to a systemic artery without its passing through the lung which acts as a filter to remove blood clots from entering the arterial circulation. Paradoxical embolism occurs when there is a defect that allows a clot to cross directly from the right to the left side of the heart as in the cases of ATRIAL SEPTAL DEFECTS or open FORAMEN OVALE. Once in the arterial circulation, a clot can travel to the brain, block an artery, and cause a STROKE.
Sinus Thrombosis, Intracranial
Formation or presence of a blood clot (THROMBUS) in the CRANIAL SINUSES, large endothelium-lined venous channels situated within the SKULL. Intracranial sinuses, also called cranial venous sinuses, include the superior sagittal, cavernous, lateral, petrous sinuses, and many others. Cranial sinus thrombosis can lead to severe HEADACHE; SEIZURE; and other neurological defects.
Carotid Artery Thrombosis
Embolism, Amniotic Fluid
Blocking of a blood vessel by CHOLESTEROL-rich atheromatous deposits, generally occurring in the flow from a large artery to small arterial branches. It is also called arterial-arterial embolization or atheroembolism which may be spontaneous or iatrogenic. Patients with spontaneous atheroembolism often have painful, cyanotic digits of acute onset.
Vena Cava Filters
Sagittal Sinus Thrombosis
Formation or presence of a blood clot (THROMBUS) in the SUPERIOR SAGITTAL SINUS or the inferior sagittal sinus. Sagittal sinus thrombosis can result from infections, hematological disorders, CRANIOCEREBRAL TRAUMA; and NEUROSURGICAL PROCEDURES. Clinical features are primarily related to the increased intracranial pressure causing HEADACHE; NAUSEA; and VOMITING. Severe cases can evolve to SEIZURES or COMA.
A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts.
Upper Extremity Deep Vein Thrombosis
DEEP VEIN THROMBOSIS of an upper extremity vein (e.g., AXILLARY VEIN; SUBCLAVIAN VEIN; and JUGULAR VEINS). It is associated with mechanical factors (Upper Extremity Deep Vein Thrombosis, Primary) secondary to other anatomic factors (Upper Extremity Deep Vein Thrombosis, Secondary). Symptoms may include sudden onset of pain, warmth, redness, blueness, and swelling in the arm.
Heparin fractions with a molecular weight usually between 4000 and 6000 kD. These low-molecular-weight fractions are effective antithrombotic agents. Their administration reduces the risk of hemorrhage, they have a longer half-life, and their platelet interactions are reduced in comparison to unfractionated heparin. They also provide an effective prophylaxis against postoperative major pulmonary embolism.
Vena Cava, Inferior
Tomography, X-Ray Computed
An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.
The presence of antibodies directed against phospholipids (ANTIBODIES, ANTIPHOSPHOLIPID). The condition is associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous thromboses. In pregnancy it can cause abortion. Of the phospholipids, the cardiolipins show markedly elevated levels of anticardiolipin antibodies (ANTIBODIES, ANTICARDIOLIPIN). Present also are high levels of lupus anticoagulant (LUPUS COAGULATION INHIBITOR).
Platelet Aggregation Inhibitors
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Cavernous Sinus Thrombosis
Formation or presence of a blood clot (THROMBUS) in the CAVERNOUS SINUS of the brain. Infections of the paranasal sinuses and adjacent structures, CRANIOCEREBRAL TRAUMA, and THROMBOPHILIA are associated conditions. Clinical manifestations include dysfunction of cranial nerves III, IV, V, and VI, marked periorbital swelling, chemosis, fever, and visual loss. (From Adams et al., Principles of Neurology, 6th ed, p711)
Lateral Sinus Thrombosis
Formation or presence of a blood clot (THROMBUS) in the LATERAL SINUSES. This condition is often associated with ear infections (OTITIS MEDIA or MASTOIDITIS) without antibiotic treatment. In developed nations, lateral sinus thrombosis can result from CRANIOCEREBRAL TRAUMA; BRAIN NEOPLASMS; NEUROSURGICAL PROCEDURES; THROMBOPHILIA; and other conditions. Clinical features include HEADACHE; VERTIGO; and increased intracranial pressure.
Embolism and Thrombosis
Fibrin Fibrinogen Degradation Products
Foramen Ovale, Patent
Protein S Deficiency
An autosomal dominant disorder showing decreased levels of plasma protein S antigen or activity, associated with venous thrombosis and pulmonary embolism. PROTEIN S is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated PROTEIN C (also a vitamin K-dependent protein), and the clinical manifestations of its deficiency are virtually identical to those of protein C deficiency. Treatment with heparin for acute thrombotic processes is usually followed by maintenance administration of coumarin drugs for the prevention of recurrent thrombosis. (From Harrison's Principles of Internal Medicine, 12th ed, p1511; Wintrobe's Clinical Hematology, 9th ed, p1523)
Ultrasonography, Doppler, Duplex
Catheterization, Central Venous
Tomography, Spiral Computed
Computed tomography where there is continuous X-ray exposure to the patient while being transported in a spiral or helical pattern through the beam of irradiation. This provides improved three-dimensional contrast and spatial resolution compared to conventional computed tomography, where data is obtained and computed from individual sequential exposures.
Protein C Deficiency
Mesenteric Vascular Occlusion
Obstruction of the flow in the SPLANCHNIC CIRCULATION by ATHEROSCLEROSIS; EMBOLISM; THROMBOSIS; STENOSIS; TRAUMA; and compression or intrinsic pressure from adjacent tumors. Rare causes are drugs, intestinal parasites, and vascular immunoinflammatory diseases such as PERIARTERITIS NODOSA and THROMBOANGIITIS OBLITERANS. (From Juergens et al., Peripheral Vascular Diseases, 5th ed, pp295-6)
The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
Lupus Coagulation Inhibitor
An antiphospholipid antibody found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications.
Ventricular Dysfunction, Right
A condition in which the RIGHT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE or MYOCARDIAL INFARCTION, and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the right ventricular wall.
Large endothelium-lined venous channels situated between the two layers of DURA MATER, the endosteal and the meningeal layers. They are devoid of valves and are parts of the venous system of dura mater. Major cranial sinuses include a postero-superior group (such as superior sagittal, inferior sagittal, straight, transverse, and occipital) and an antero-inferior group (such as cavernous, petrosal, and basilar plexus).
Antithrombin III Deficiency
Activated Protein C Resistance
A condition characterized by a chronically swollen limb, often a leg with stasis dermatitis and ulcerations. This syndrome can appear soon after phlebitis or years later. Postphlebitic syndrome is the result of damaged or incompetent venous valves in the limbs. Distended, tortuous VARICOSE VEINS are usually present. Leg pain may occur after long period of standing.
Heart Septal Defects, Atrial
Developmental abnormalities in any portion of the ATRIAL SEPTUM resulting in abnormal communications between the two upper chambers of the heart. Classification of atrial septal defects is based on location of the communication and types of incomplete fusion of atrial septa with the ENDOCARDIAL CUSHIONS in the fetal heart. They include ostium primum, ostium secundum, sinus venosus, and coronary sinus defects.
Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
Tissue Plasminogen Activator
A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.
The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).
Pregnancy Complications, Cardiovascular
Arterial Occlusive Diseases
Partial Thromboplastin Time
The time required for the appearance of FIBRIN strands following the mixing of PLASMA with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of BLOOD COAGULATION. It is used as a screening test and to monitor HEPARIN therapy.
Predictive Value of Tests
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Intermittent Pneumatic Compression Devices
Blood Coagulation Disorders
Disseminated Intravascular Coagulation
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
Arteriovenous Shunt, Surgical
International Normalized Ratio
System established by the World Health Organization and the International Committee on Thrombosis and Hemostasis for monitoring and reporting blood coagulation tests. Under this system, results are standardized using the International Sensitivity Index for the particular test reagent/instrument combination used.
Angioplasty, Balloon, Coronary
Magnetic Resonance Angiography
A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.
Ultrasonography applying the Doppler effect, with frequency-shifted ultrasound reflections produced by moving targets (usually red blood cells) in the bloodstream along the ultrasound axis in direct proportion to the velocity of movement of the targets, to determine both direction and velocity of blood flow. (Stedman, 25th ed)
Antiphospholipid antibodies found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. The antibodies are detected by solid-phase IMMUNOASSAY employing the purified phospholipid antigen CARDIOLIPIN.
Disease Models, Animal
Sensitivity and Specificity
Heart Valve Prosthesis
Technetium Tc 99m Aggregated Albumin
Blood Coagulation Factors
Magnetic Resonance Imaging
Ultrasonography, Doppler, Color
Ultrasonography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image. This type of ultrasonography is well-suited to identifying the location of high-velocity flow (such as in a stenosis) or of mapping the extent of flow in a certain region.
Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.
Blood Vessel Prosthesis
A lipid cofactor that is required for normal blood clotting. Several forms of vitamin K have been identified: VITAMIN K 1 (phytomenadione) derived from plants, VITAMIN K 2 (menaquinone) from bacteria, and synthetic naphthoquinone provitamins, VITAMIN K 3 (menadione). Vitamin K 3 provitamins, after being alkylated in vivo, exhibit the antifibrinolytic activity of vitamin K. Green leafy vegetables, liver, cheese, butter, and egg yolk are good sources of vitamin K.
Superior Sagittal Sinus
The long large endothelium-lined venous channel on the top outer surface of the brain. It receives blood from a vein in the nasal cavity, runs backwards, and gradually increases in size as blood drains from veins of the brain and the DURA MATER. Near the lower back of the CRANIUM, the superior sagittal sinus deviates to one side (usually the right) and continues on as one of the TRANSVERSE SINUSES.
Pregnancy Complications, Hematologic
Urokinase-Type Plasminogen Activator
beta 2-Glycoprotein I
A 44-kDa highly glycosylated plasma protein that binds phospholipids including CARDIOLIPIN; APOLIPOPROTEIN E RECEPTOR; membrane phospholipids, and other anionic phospholipid-containing moieties. It plays a role in coagulation and apoptotic processes. Formerly known as apolipoprotein H, it is an autoantigen in patients with ANTIPHOSPHOLIPID ANTIBODIES.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Severity of Illness Index
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
Diagnostic and therapeutic procedures that are invasive or surgical in nature, and require the expertise of a specially trained radiologist. In general, they are more invasive than diagnostic imaging but less invasive than major surgery. They often involve catheterization, fluoroscopy, or computed tomography. Some examples include percutaneous transhepatic cholangiography, percutaneous transthoracic biopsy, balloon angioplasty, and arterial embolization.
Rare chronic inflammatory disease involving the small blood vessels. It is of unknown etiology and characterized by mucocutaneous ulceration in the mouth and genital region and uveitis with hypopyon. The neuro-ocular form may cause blindness and death. SYNOVITIS; THROMBOPHLEBITIS; gastrointestinal ulcerations; RETINAL VASCULITIS; and OPTIC ATROPHY may occur as well.
von Willebrand Factor
A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor VIII/von Willebrand factor complex. The von Willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. It functions in adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND DISEASES is due to the deficiency of this factor.
A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.
An endogenous family of proteins belonging to the serpin superfamily that neutralizes the action of thrombin. Six naturally occurring antithrombins have been identified and are designated by Roman numerals I to VI. Of these, Antithrombin I (see FIBRIN) and ANTITHROMBIN III appear to be of major importance.
Inherited prothrombotic risk factors and cerebral venous thrombosis. (1/698)Fifteen patients with cerebral venous thrombosis were ascertained retrospectively. Their case notes were reviewed, and stored or new blood was assayed for factor V Leiden (FVL) mutation, prothrombin gene mutation 20201A, and 5,10 methylene tetrahydrofolate reductase (MTHFR) C677T mutation. A clinical risk factor was identified in 13 patients--the oral contraceptive pill (5), puerperium (1), HRT (1), mastoiditis (1), dehydration (1), lumbar puncture and myelography (1), carcinoma (1), lupus anticoagulant (2). In addition, two patients had the FVL mutation and five (one of whom also had the FVL mutation) were homozygous for the MTHFR mutation. The latter showed a higher than expected frequency compared to 300 healthy controls from South Wales (OR 3.15.95% Cl 1.01-9.83). No patient had the prothrombin 20201A mutation. Two patients died and three had a monocular visual deficit following anticoagulation (13) or thrombolytic (2) treatment, but there was no association between the presence of a primary prothrombotic risk factor and outcome. These results confirm the importance of investigating patients for both clinical predisposing factors and primary prothrombotic states. (+info)
Computerised axial tomography in patients with severe migraine: a preliminary report. (2/698)Patients suffering from severe migraine, usually for many years, have been examined by the EMI scanner between attacks. Judged by criteria validated originally by comparison with pneumoencephalography, about half of the patients showed evidence of cerebral atrophy. Perhaps of more significance than generalised atrophy was the frequency of areas of focal atrophy and of evidence of infarction. (+info)
Rupture mechanism of a thrombosed slow-growing giant aneurysm of the vertebral artery--case report. (3/698)A 76-year-old male developed left hemiparesis in July 1991. The diagnosis was thrombosed giant vertebral artery aneurysm. He showed progressive symptoms and signs of brainstem compression, but refused surgery and was followed up without treatment. He died of rupture of the aneurysm and underwent autopsy in March 1995. Histological examination of the aneurysm revealed fresh clot in the aneurysmal lumen, old thrombus surrounding the aneurysmal lumen, and more recent hemorrhage between the old thrombus and the inner aneurysmal wall. The most important histological feature was the many clefts containing fresh blood clots in the old thrombus near the wall of the distal neck. These clefts were not lined with endothelial cells, and seemed to connect the lumen of the parent artery with the most peripheral fresh hemorrhage. However, the diameter of each of these clefts is apparently not large enough to transmit the blood pressure of the parent artery. Simple dissection of the aneurysmal wall by blood flow in the lumen through many clefts in the old thrombus of the distal neck may be involved in the growth and rupture of thrombosed giant aneurysms of the vertebral artery. (+info)
Cerebral venous thrombosis: combined intrathrombus rtPA and intravenous heparin. (4/698)BACKGROUND AND PURPOSE: We chose to evaluate the safety and efficacy of combined intrathrombus rtPA and intravenous heparin in cerebral venous thrombosis (CVT). METHODS: We treated 12 patients with symptoms of 1 to 40 days' duration (eg, headache, somnolence, focal deficits, seizures, and nausea and vomiting). Pretreatment MRI disclosed subtle hemorrhagic venous infarction in 4 patients, obvious hemorrhagic infarction in 2, small parenchymal hemorrhage from recent pallidotomy in 1, and no focal lesion in 5. Magnetic resonance venography and contrast venography identified thrombi in the superior sagittal sinus (SSS) in 3 patients; transverse/sigmoid sinus (TS/SS) in 2; SSS and both TS/SS in 1; SSS and 1 TS/SS in 5; and SSS, 1 TS/SS, and straight sinus in 1 patient. A loading dose of rtPA was instilled throughout the clot at 1 mg/cm, followed by continuous intrathrombus infusion at 1 to 2 mg/h. Intravenous heparin was infused concomitantly. RESULTS: Flow was restored completely in 6 patients and partially in 3, with a mean rtPA dose of 46 mg (range, 23 to 128 mg) at a mean time of 29 hours (range, 13 to 77 hours). Symptoms improved in these 9 patients concomitantly with flow restoration. Flow could not be restored in 3 patients. In 1 of them, treatment was stopped when little progress had been made, and fibrinogen level dropped to 118 mg/dL. In the other 2 patients, hemorrhagic worsening occurred, and treatment was abbreviated after initial rtPA dosing. In 1 of these, the hematoma was evacuated. CONCLUSIONS: Our experience with intrathrombus rtPA in conjunction with intravenous heparin in patients with CVT is encouraging. This therapy should probably be regarded as unsafe in patients with obvious hemorrhage. Time to restore flow may be faster than with urokinase (an average of 71 hours has been reported for 29 documented patients). Further evaluation of rtPA with heparin in CVT is warranted. (+info)
Cerebral injury after cardiac surgery: identification of a group at extraordinary risk. Multicenter Study of Perioperative Ischemia Research Group (McSPI) and the Ischemia Research Education Foundation (IREF) Investigators. (5/698)BACKGROUND AND PURPOSE: Cerebral injury after cardiac surgery is now recognized as a serious and costly healthcare problem mandating immediate attention. To effect solution, those subgroups of patients at greatest risk must be identified, thereby allowing efficient implementation of new clinical strategies. No such subgroup has been identified; however, patients undergoing intracardiac surgery are thought to be at high risk, but comprehensive data regarding specific risk, impact on cost, and discharge disposition are not available. METHODS: We prospectively studied 273 patients enrolled from 24 diverse US medical centers, who were undergoing intracardiac and coronary artery surgery. Patient data were collected using standardized methods and included clinical, historical, specialized testing, neurological outcome and autopsy data, and measures of resource utilization. Adverse outcomes were defined a priori and determined after database closure by a blinded independent panel. Stepwise logistic regression models were developed to estimate the relative risks associated with clinical history and intraoperative and postoperative events. RESULTS: Adverse cerebral outcomes occurred in 16% of patients (43/273), being nearly equally divided between type I outcomes (8.4%; 5 cerebral deaths, 16 nonfatal strokes, and 2 new TIAs) and type II outcomes (7.3%; 17 new intellectual deterioration persisting at hospital discharge and 3 newly diagnosed seizures). Associated resource utilization was significantly increased--prolonging median intensive care unit stay from 3 days (no adverse cerebral outcome) to 8 days (type I; P<0.001) and from 3 to 6 days (type II; P<0.001), and increasing hospitalization by 50% (type II, P=0.04) to 100% (type I, P<0.001). Furthermore, specialized care after hospital discharge was frequently necessary in those with type I outcomes, in that only 31% returned home compared with 85% of patients without cerebral complications (P<0.001). Significant risk factors for type I outcomes related primarily to embolic phenomena, including proximal aortic atherosclerosis, intracardiac thrombus, and intermittent clamping of the aorta during surgery. For type II outcomes, risk factors again included proximal aortic atherosclerosis, as well as a preoperative history of endocarditis, alcohol abuse, perioperative dysrhythmia or poorly controlled hypertension, and the development of a low-output state after cardiopulmonary bypass. CONCLUSIONS: These prospective multicenter findings demonstrate that patients undergoing intracardiac surgery combined with coronary revascularization are at formidable risk, in that 1 in 6 will develop cerebral complications that are frequently costly and devastating. Thus, new strategies for perioperative management--including technical and pharmacological interventions--are now mandated for this subgroup of cardiac surgery patients. (+info)
Thrombolysis with tissue plasminogen activator alters adhesion molecule expression in the ischemic rat brain. (6/698)BACKGROUND AND PURPOSE: We tested the hypothesis that treatment of embolic stroke with recombinant human tissue plasminogen activator (rhtPA) alters cerebral expression of adhesion molecules. METHODS: Male Wistar rats were subjected to middle cerebral artery occlusion by a single fibrin-rich clot. P-selectin, E-selectin, and intercellular adhesion molecule-1 (ICAM-1) immunoreactivity was measured at 6 or 24 hours after embolic stroke in control rats and in rats treated with rhtPA at 1 or 4 hours after stroke. To examine the therapeutic efficacy of combined rhtPA and anti-ICAM-1 antibody treatment at 4 hours after embolization, ischemic lesion volumes were measured in rats treated with rhtPA alone, rats treated with rhtPA and anti-ICAM-1 antibody, and nontreated rats. RESULTS: Administration of rhtPA at 1 hour after embolization resulted in a significant reduction of adhesion molecule vascular immunoreactivity after embolization in the ipsilateral hemisphere compared with corresponding control rats. However, when rhtPA was administered to rats at 4 hours after embolization, significant increases of adhesion molecule immunoreactivity in the ipsilateral hemisphere were detected. A significant increase of ICAM-1 immunoreactivity was also detected in the contralateral hemisphere at 24 hours after ischemia. A significant reduction in lesion volume was found in rats treated with the combination of rhtPA and anti-ICAM-1 antibody compared with rats treated only with rhtPA. CONCLUSIONS: The present study suggests that the time of initiation of thrombolytic therapy alters vascular immunoreactivity of inflammatory adhesion molecules in the ischemic brain and that therapeutic benefit can be obtained by combining rhtPA and anti-ICAM-1 antibody treatment 4 hours after stroke. (+info)
EEG surveillance as a means of extending operability in high risk carotid endarterectomy. (7/698)Some patients who have transient ischemic attacks are denied operation because severe occlusive lesions in other extra-cranial arteries may be inappropriately interpreted as constituting an unacceptable surgical risk, or because the lesion is so distal as to make its removal hazardous. Failure of endarterectomy is usually due to incomplete removal of the lesion or to thrombosis upon the frayed intima. Such lesions require excellent visualization and meticulous surgical technique -- not always possible with a shunt. Among 130 consecutive carotid endarterectomies performed under general anesthesia, EEG changes consistent with cerebral ischemia appeared in only nine (7%). These patients required a shunt. In 11 patients normal EEG tracings were obtained during endarterectomy despite contralateral carotid occlusion. None of these patients had a neurological deficit. Continuous EEG monitoring is a reliable method of detecting changes in cerebral perfusion, permits a more meticulous endarterectomy in high-lying lesions without a shunt, and extends operability in high risk patients. Angiographical findings may be an unreliable predictor concerning risk of endarterectomy. (+info)
A prospective study of cerebrovascular disease in Japanese rural communities, Akabane and Asahi. Part 1: evaluation of risk factors in the occurrence of cerebral hemorrhage and thrombosis. (8/698)An epidemiological study of cerebrovascular disease in Akabane and Asahi, Japan, was made. (These cities are located near Nagoy, Japan.) The study population included 4,737 men and women aged 40 to 79 at the time of entry into the study. There were 4,186 persons who were examined and, of these, 264 cases of cerebrovascular attacks were observed between 1964 and 1970. The incidence rate of stroke in those persons not responding to the survey was 15.9 times higher than in those persons examined according to person-year observation in Akabane. The risk factors for cerebral hemorrhage and thrombosis were evaluated by age-adjusted and sex-adjusted relative risks. The predisposing factors to cerebral hemorrhage appeared to be high blood pressure, high left R wave, ST depression, T abnormality, capillary fragility counts, previous medical history of stroke and albuminuria. For cerebral thrombosis, the predisposing factors appeared to be high blood pressure, ST depression and funduscopic sclerotic findings, and those factors assumed to be significant were glycosuria and smoking habits. Ocular funduscopic abnormality was the most prominent risk factor for cerebral thrombosis, while high blood pressure and ECG abnormalities were highly related to cerebral hemorrhage. It was suggested that those subjects with a relatively higher blood pressure may have a higher relative risk of cerebral hemorrhage than those with a lower (normal range) blood pressure. A previous or family history of stroke also appeared significantly related to cerebral hemorrhage. (+info)
Cerebral infarction and cerebral thrombosis in younger men | masterchensays
Cerebral infarction and cerebral thrombosis in younger men Chinese mainland doctors have noticed that cerebral infarction and cerebral thrombosis are occurring more frequently in younger men. They used to occur mostly among older men. They can lead to microstrokes or cerebrovascular accidents and partial physical paralyses. In general, cerebral hemorrhage accounts for only 15% while…
Cerebral Thrombosis - Days of Fear - Days of Joy, Artist Asbjorn Lonvig
Cerebral Thrombosis - Days of Fear - Days of Joy - Dedicated to my wife and family. Cerebral Thrombosis: A blood clot, a semisolid mass of coagulated red and white blood cells in a cerebral artery or vein.
Cerebral Thrombosis & Poor Outcome & Weakness<...
Cerebral Thrombosis, Poor Outcome, Weakness Symptom Checker: Possible causes include Subarachnoid Hemorrhage, Stroke, Intracranial Sinus Thrombosis. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.
What is Transient Cerebral Thrombosis? | Mediologiest
What is Transient Cerebral Thrombosis? By transient ischemic attack (TIA) refers to a short time (less than 24 hours) the loss of parts of the brain function caused by a transient occlusion of an artery in the brain or in brain afferent arteries. Symptoms The most common symptoms are transient (under 24 hours)
Cerebral artery thrombosis - Stock Image C006/3975 - Science Photo Library
Thrombosis of a cerebral artery. The cerebral thrombosis (obstruction of a cerebral artery by thrombus) or cerebral embolism (obstruction of a cerebral artery by an element coming from another part of the body) leads to an ischemia (reduction of the blood intake), verily a cerebral infarction (death or necrosis of the unirrigated region of the brain). - Stock Image C006/3975
Pollution Victim in Henan | Greenpeace East Asia
58-year-old Xue Guangliang, a villager of Zhangying (Zhao Lin village) in Wugang city, developed cerebral thrombosis five years ago. He always exercises in the village with a chair. There are more than ten cerebral thrombosis patients in the village, located along the polluted river Hong.
Intracranial Pressure Gradients in Experimental Cerebral Infarction | Springer for Research & Development
This study was undertaken in order to examine for ourselves the question whether intracranial pressure gradients occur in the course of experimental cerebral ischemia, and if they did occur, to...
EVALUATION OF CEREBRAL THROMBOEMBOLISM AFTER TAVR - AdisInsight
To evaluate the occurrence and extent of cerebral embolization (total new lesion volume) in patients before TAVR versus 3 months after TAVR by cerebral MRI
Heart-and-Stroke-Encyclopedia - ischemic stroke
Ischemic stroke occurs when a blood clot or other particle blocks an artery in the brain or an artery leading to the brain. This causes brain cells to die or be injured. Cerebral thrombosis and cerebral embolism are ischemic strokes.. ...
Blacknell Family History - Frederick BLACKNALL b. 21/03/1859
Cerebral Thrombosis - blood clot in brain (possibly leading to stroke) Arteria Sclerosis - hardening of the arteries Carcinoma of stomach - Gastric cancer; Attached To Birth, ...
Younger, middle-aged people continue losing their lives for adenovirus COVID vaccine experiment - The BL
The AstraZeneca and Johnson & Johnson experimental adenovirus COVID shots appear to be far more deadly to younger and middle-aged people, people compared to the mRNA shots from Pfizer and Moderna.. More details about adenovirus COVID vaccine deaths have been recently reported by Health Impact News which indicates victims of the vaccine range from 27 to 55 years old, and most of them suffer from blood clots.. Australian Genene Norris, 48, and Canadian Francine Boyer, 54 both died a few days after having the COVID-19 vaccine from AstraZeneca.. Boyer was plagued by exhaustion and crippling headaches. She went to the nearest hospital, but doctors could not find out what was wrong with her. She was then transferred to the Montreal Neurological Institute Hospital, where she was diagnosed with cerebral thrombosis or blood clots to the brain. She passed away on April 23.. Meanwhile, Norris became ill almost immediately after receiving the AstraZeneca vaccine. Four days after the vaccination, doctors ...
Blacknell Family History - Joseph BLACKNALL b. 31/10/1784
xxii. Register of Births Marriages & Deaths10; Page Death/Nottingham/Nottingham North/1948/31; Text 31 Twelfth January 1948 City Hospital Frederick BLACKNELL Male 80 years of 19 Acton Avenue Old Basford formerly a Farm Labourer I(a) Cerebral Thrombosis I(b) Arteria Sclerosis II Carcinoma of stomach E Owen Daughter of 19 Acton Avenue Old Basford Nottingham Thirteenth January 1948 J Toft Registrar; [Source Record]; Certainty Unknown (4 ...
Cerebral embolism during edoxaban administration for venous
In March 2017, a 63-year-old woman with no smoking or major medical history was incidentally observed to have a tumor in the left upper lobe on a computed tomography (CT) scan. As a result of a detail...
Cerebral Thrombosis & Cerebrospinal Fluid Protein Increased & Poor Outcome<...
Cerebral Thrombosis, Cerebrospinal Fluid Protein Increased, Poor Outcome Symptom Checker: Possible causes include Subarachnoid Hemorrhage, Cerebral Thrombosis, Stroke. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.
Applying for Life Insurance after a Cerebral Embolism and/or Cerebral Thrombosis.
Our best tip for anyone looking to purchase a traditional term or whole life insurance policy with a pre-existing medical condition like a Cerebral Embolism and/or Cerebral Thrombosis, is that youre…
Cerebral thrombosis associated with active Crohns disease.<...
TY - JOUR. T1 - Cerebral thrombosis associated with active Crohns disease.. AU - Calderón, R.. AU - Cruz-Correa, M. R.. AU - Torres, E. A.. PY - 1998. Y1 - 1998. N2 - An increased incidence of cerebral thromboembolic events has been reported in young patients with inflammatory bowel disease (IBD). It has been suggested that a hypercoagulable state is associated with clinical activity of the disease, with elevation of factors V, VIII, fibrinogen and platelets and a lowering of anti-thrombin III. We present the case of a 35 y/o male with refractory Crohns disease who complained of headaches, blurred vision and tonic-clonic seizures. The studies demonstrated an ischemic stroke of the left cerebral hemisphere, without vascular abnormalities. Elevation of factor VIII, platelets, and antithrombin III were found. The symptoms were relieved with medical treatment and the patient has continued in good health after resection of the diseased terminal ileum.. AB - An increased incidence of cerebral ...
Weihai police emergency rescue roadside old man collapsed elderly suffering from cerebral thrombosis easeljs | tom365.com...
Weihai police emergency rescue roadside old man collapsed elderly suffering from cerebral thrombosis - Beijing newspaper Weihai September 16th news (reporter Tao Xiangyin) 16 morning, in the streets of Weihai, a roadside old man collapsed with heart disease. After the police found on duty, immediately call 120 emergency phone, and the elderly were rescued. Later, the doctor said, two minutes later, the old man lives. As of 18 oclock that day, the old man is still in hospital for treatment. 16 morning, Weihai Traffic Police Brigade police on duty Sun Kai to West road. At 10:15 PM, Sun Kaizheng on the west a few illegal parked vehicles posted a ticket, suddenly heard a whistle behind the vehicle. He turned around and found dozens of meters outside the road on the eastern side of the motor vehicle lane, a man fell to the ground. Sun Kai quickly ran past, found lying on the ground was a more than and 60 year old man, koutubaimo, twitching. Sun Kai hastened to call the 120 emergency phone, and ...
Delayed cerebral thrombosis complicating pneumococcal meningitis: an autopsy study | Springer for Research & Development
Background Delayed cerebral thrombosis (DCT) is a devastating cerebrovascular complication in patients with excellent initial recovery of pneumococcal meningitis. The aetiology is unknown, but direct...
Top Cerebral Artery Thrombosis Hospitals in Thane | Credihealth
View details of top cerebral artery thrombosis hospitals in Thane. Get guidance from medical experts to select best cerebral artery thrombosis hospital in Thane
Microembolism - definition of Microembolism by The Free Dictionary
Define Microembolism. Microembolism synonyms, Microembolism pronunciation, Microembolism translation, English dictionary definition of Microembolism. n. 1. Obstruction or occlusion of a blood vessel by an embolus. 2. An embolus. em′bo·lis′mic adj. n 1. the occlusion of a blood vessel by an embolus 2....
A NEW METHOD FOR AUTOMATIC DIFFERENTIATION BETWEEN CEREBRAL EMBOLI AND ARTEFACTS | Stroke
P29 Introduction: Cerebral embolus monitoring systems suitable for routine clinical use must have the ability to automatically recognise and differentiate between artefacts and emboli. This has to date proven to be an extremely difficult problem to solve. Methods: In this study we present a new advancement with regard to the automatic recognition of cerebral emboli and differentiation from artefacts based on a binary decision tree which includes a completely new parameter. This is the 1/4 Doppler shift for the maximum power reflection of an embolic event at 2.5 MHz insonation frequency compared to 2.0 MHz. A new multifrequency transcranial Doppler system together with this software was used in this study of 2000 artefacts and 100 embolic events in one heart valve patient. The level for event recognition was set at 5db above background Doppler power. The artefacts in 2 healthy controls consisted of 200: tapping the probe, 200: tapping the skull, 200: talking (counting), 200: swallowing, 400: ...
Effect of ARC1779 on Cerebral Microembolism in Patients Undergoing Carotid Endarterectomy - Full Text View - ClinicalTrials.gov
Study drug treatment will be initiated 1 hour prior to the induction of anesthesia with a loading dose given over 1 hour in 3 successively increasing, 20-minute step infusions. The ARC1779 treatment group will be dosed to achieve a target ARC1779 steady-state plasma concentration of 3 Ug/mL, using a loading dose infusion sequence of 0.0015 mg/kg/min for 20 minutes, 0.003 mg/kg/min for the next 20 minutes, and then 0.006 mg/kg/min for the final 20 minutes; thereafter, their maintenance infusion rate is to be 0.0006 mg/kg/min ...
Arterial air embolism in the cat brain | Meta
In cats air embolism of the brain was produced by injecting 0.6 ml blood foam into the innominate artery proximal to the origin of both common carotid arteries. Air embolism caused transient ischemia of the brain, reaching a maximum within 1 min after injection. Resolution of the air embolism began a few minutes later and was completed within 15 min in the center and within 30 min in the border zone of the main supplying arteries. During this phase tissue perfusion was inhomogenous with reduced flow rates in some areas and reactive hyperemia up to 300% in others. This resulted in venous hyperoxia and a decrease of arteriovenous oxygen difference to as low as 2 ml/100 ml blood. Reactive hyperemia was accompanied by brain swelling and an increase in intracranial pressure from 3.6 +/- 1.2 to 12.3 +/- 2.0 mm Hg. The reason for hyperemia was a decrease of cortical pH which fell from 7.33 +/- 0.03 to 7.03 +/- 0.05, and which caused a dilation of pial arteries up to 260%. Immediately after embolism, ...
Air Embolism, Venous Air Embolism, Arterial Air Embolism - ONA
We offer clinical cancer updates, treatment guidance, and research news to the oncology nursing community. Visit us often for drug therapy testing results, patient care information and more. Download our FREE app today.
NewYork-Presbyterian Queens - Glossary - Non-Traumatic Emergencies
return to top]. carbon monoxide (CO) - a colorless, odorless gas which can be created whenever a fuel (such as wood, gasoline, coal, natural gas, or kerosene) is burning.. cardiac arrest - the stopping of heartbeat.. cardiopulmonary resuscitation (CPR) - an emergency method of life-saving. Artificial respirations and chest compressions are used to restart the heart and lungs.. central nervous system - the brain and the spinal cord.. cerebral embolism - a brain attack that occurs when a wandering clot (embolus) or some other particle forms in a blood vessel away from the brain - usually in the heart.. cerebral hemorrhage - a type of stroke occurs when a defective artery in the brain bursts, flooding the surrounding tissue with blood.. cerebral thrombosis - the most common type of brain attack; occurs when a blood clot (thrombus) forms and blocks blood flow in an artery bringing blood to part of the brain.. cerebrovascular accident - apoplexy or stroke; an impeded blood supply to the ...
Strokes: Ischemic and Hemorrhagic · Guardian Liberty Voice
The fourth leading cause of death in the United States is a stroke. A person dies from a stroke every four minutes. Someone has a stroke every four seconds. Strokes happen when the blood supply to the brain is altered in some form, either not enough blood or too much blood on the brain. During a stroke, brain cells die due to lack of oxygen and nutrients. The best way to avoid a stroke is to live a healthy lifestyle.. Ischemic strokes account for 87 percent and hemorrhagic strokes account for 13 percent of all cases. An ischemic stroke is caused when a blood clot or a mass blocks the blood flow to the brain. The underlying condition for this obstruction, is the result of fatty deposits along the vessel walls, called plaque. This is called, atherosclerosis. This can cause two different types of obstruction, cerebral thrombosis, is a thrombus, (blood clot), which develops at the clogged part of the vessel. The other type is a cerebral embolism, which is a blood clot that forms in a different part ...
Cocaine Use and Ischemic Stroke | Promises Treatment Centers Austin
The brain sustains its normal function by taking in a constant stream of oxygen-rich blood from its supply of arteries. If this flow of blood ceases for even short periods of time, the cells in any affected area of the brain will die prematurely and trigger the onset of some form of brain damage. Whatever the underlying nature of the blood flow disruption, doctors refer to this set of circumstances as a stroke. As noted previously, an ischemic stroke involves some sort of blockage in a brain artery. In the general population, a blockage in one of these arteries is typically the result of cholesterol-based fatty deposits that accumulate over time on the interior artery walls; doctors call this buildup process atherosclerosis or arteriosclerosis. In some cases, the accumulation of fatty deposits helps form an artery-blocking blood clot directly within the brain by acting as an anchoring point for the abnormal clumping of blood components called platelets; this is known as a cerebral thrombosis. In ...
Blood Clot in The Brain or Brain Haemorrhage | Mediologiest
Blood Clot in The Brain or Brain Haemorrhage What is cerebral thrombosis or a stroke? An ischemic stroke is the most common cause of stroke (stroke). Clot stops the blood and oxygen supply to the brain cells in the blood vessel supply area, and can cause sudden onset, unilateral paralysis and sensory disturbances.
Alternative treatment to corticosteroids in steroid sensitive idiopathic nephrotic syndrome. | Archives of Disease in Childhood
A review was undertaken of the use of alternative immunosuppressive treatment in addition to corticosteroids in a cohort of 429 children with steroid sensitive nephrotic syndrome (SSNS) treated between 1980 and 1994. Two hundred and twenty two children (52%) received at least one course of alternative treatment, 98 (23%) two, and 43 (10%) three. Cyclophosphamide was administered to 196 children (46%); in 181 it was the first course of alternative treatment and in 104 (57%) of those it was also the last (final course). Levamisole was given to 56 children (13%) and cyclosporin to 53 (12%). Fifteen children in whom cyclosporin failed were treated with chlorambucil. A few patients received azathioprine or vincristine. Ten children developed secondary steroid resistance, of whom five progressed to chronic renal failure. Acute complications included reversible renal failure, septicaemia, peritonitis, convulsions, and cerebral thrombosis. There were three deaths. It is concluded that half of the ...
Janesville Wisconsin Locations - Access Genealogy
Rufus E. Bean of Milton, well-known civic and political leader of Umatilla County, died Saturday afternoon [April 5] at a Walla Walla hospital of cerebral thrombosis. Born January 1, 1876 at Virgil City, Mo., he was the youngest of 13 children. After four years of schooling in a one-room school in Michigan, he learned telegraphy at Janesville, Wis., where his teacher was George Parker, fountain pen inventor. He worked as a telegraph operator at Floodwood, Minn., and at Portland. He became and agent for the O.W.R. & N. Company at Milton, and lived in this community for the rest of his life, with the exception of three years at Tekoa. In 1904 he married Nellie W. Sanderson at Pomeroy. She survives him, as do three children, Mrs. A. W. Priaul of Portland, R. Allan Bean of Richmond, Calif., and Mrs. Robert E. Lee of Forest Grove, and eight grandchildren. He is also survived by a sister, Mrs. Anna Reese of Caro, Mich., and a brother, David E. Beam of Pigeon, Mich. He was widely known throughout the ...
Sugar? | Cancer Survivors Network
PREFACE. One morning at breakfast, the autumn of 1955, my explorer-anthropologist husband, Vilhjalmur Stefansson, asked me if he might return to the Stone Age Eskimo sort of all-meat diet he had thrived on during the most active part of his arctic work. Two years before, he had suffered a mild cerebral thrombosis, from which he had practically recovered. But he had not yet succeeded in losing the ten pounds of overweight his doctor wanted him to be rid of. By will power and near starvation, he had now and then lost a few of them; but the pounds always came back when his will power broke down. Doubtless partly through these failures, Stef had grown a bit unhappy, at times grouchy.. My first reaction to his Stone Age diet proposal was dismay. I have three jobs. I lecture, in and out of town, and enjoy the innumerable extracurricular activities of our New England college town of Hanover, New Hampshire. Forenoons I write books about the arctic, for teen-agers and uninformed adults, to be able to ...
Neuroanatomy Stroke Model: Stroke Mechanisms
In an embolic stroke, a piece of material (or embolus) travels from a distant location and lodges in the blood vessel, occluding it. The most common type of embolus is a blood clot. Because the blockage arrives from another location, the onset of embolic strokes is usually quicker than that of thrombotic strokes. As well, because of this, treatment of the stroke must also include determining the source of the embolus so as to prevent further emboli. Because a blood clot is the most common type of embolus, all of the risk factors listed above for thrombotic stroke (Virchow Triad) also apply to embolic strokes ...
NewYork-Presbyterian Queens - Types of Stroke
Thrombotic strokes are strokes caused by a thrombus (blood clot) that develops in the arteries supplying blood to the brain. This type of stroke is usually seen in older persons, especially those with high-cholesterol levels and atherosclerosis (a build-up of fat and lipids inside the walls of blood vessels).. Sometimes, symptoms of a thrombotic stroke can occur suddenly and often during sleep or in the early morning. At other times, it may occur gradually over a period of hours or even days. This is called a stroke-in-evolution.. Thrombotic strokes may be preceded by one or more mini-strokes, called transient ischemic attacks, or TIAs. TIAs may last for a few minutes or up to 24 hours, and are often a warning sign that a stroke may occur. Although usually mild and transient, the symptoms caused by a TIA are similar to those caused by a stroke.. Another type of stroke that occurs in the small blood vessels in the brain is called a lacunar infarct. The word lacunar comes from the Latin word ...
Health Article | UH Harrington Heart & Vascular Institute | University Hospitals | Cleveland, OH
Thrombotic strokes are strokes caused by a thrombus (blood clot) that develops in the arteries supplying blood to the brain. This type of stroke is usually seen in older persons, especially those with high cholesterol and atherosclerosis (a buildup of fat and lipids inside the walls of blood vessels) or diabetes. Sometimes, symptoms of a thrombotic stroke can occur suddenly and often during sleep or in the early morning. At other times, it may occur gradually over a period of hours or even days.. Thrombotic strokes may be preceded by one or more mini-strokes, called transient ischemic attacks, or TIAs. TIAs may last for a few minutes or up to 24 hours, and are often a warning sign that a stroke may occur. Although usually mild and transient, the symptoms caused by a TIA are similar to those caused by a stroke.. Another type of stroke that occurs in the small blood vessels in the brain is called a lacunar infarct. The word lacunar comes from the Latin word meaning hole or cavity. Lacunar ...
Health Library | SCL Health
Thrombotic strokes are strokes caused by a blood clot (thrombus) that develops in the arteries supplying blood to the brain. This type of stroke is usually seen in older people, especially those with high cholesterol and a buildup of fat and lipids inside the walls of blood vessels (atherosclerosis) or diabetes. Sometimes, symptoms of a thrombotic stroke can occur suddenly. They can happen during sleep or in the early morning. At other times, it may occur gradually over a period of hours or even days.. Mini-strokes are also called transient ischemic attacks (TIAs) One of more of these may happen before a thrombotic stroke. TIAs may last for a few minutes or up to 24 hours. They are often a warning sign that a stroke may occur. Symptoms of a TIA are often mild and temporary, but they are similar to those caused by a stroke.. Another type of stroke that occurs in the small blood vessels in the brain is called a lacunar infarct. The word lacunar comes from the Latin word meaning hole or cavity. ...
Erfworld Forums • Inner Peace (Through Superior Firepower) - Episode 039 - Page 3
As for Wandas appearance, I rather imagine that Wanda is exploring not only Croakamancy but the other magical disciplines. As a result, she is slowly being wasted because she isnt tuned to handle the other disciplines on a regular basis (I imagine something similar to what happened to Drool Rockworm w/ the Staff of Law in the first Covenant trilogy). What were seeing is Wanda being used up or twisted by other magical disiplines as she tries to understand magic, Fate, and her own powers as a Croakamancer. Perhaps this is why she tells Parson in Book 1 that other magic is hard ...
Abstract W P176: Relationship Between Right-to-Left Shunting and Microembolic Signals on Transcranial Doppler Monitoring |...
Background: Transcranial doppler-monitoring (TCM) has been used to identify patients at risk for embolic stroke and aids in identification of stroke mechanism. Limited data exists on the occurrence of microembolic signals (MES) on TCM and the presence of right-to-left shunting (RLS), most commonly through a patent foramen ovale. Our objective was to determine if a relationship exists between the presence of a RLS on transcranial doppler-bubble (TCB) and MES on TCM, and if the degree of shunting correlated with increased number of MES.. Methods: A retrospective chart review was conducted of 113 inpatients that underwent both TCB for the detection of a RLS and TCM during their admission for ischemic stroke at the Cleveland Clinic between 2011 and 2012. TCM was performed for 20 minutes in all patients. Both TCM and TCB used standardized protocols and machines. Data collected included demographics, presence of a shunt, and stroke mechanism.. Results: Mean age of the study cohort was 57.9 years and ...
Nicergoline - Wikipedia
Nicergoline (INN, marketed under the trade name Sermion) is an ergot derivative used to treat senile dementia and other disorders with vascular origins. It decreases vascular resistance and increases arterial blood flow in the brain, improving the utilization of oxygen and glucose by brain cells. It has similar vasoactive properties in other areas of the body, particularly the lungs. It is used for vascular disorders such as cerebral thrombosis and atherosclerosis, arterial blockages in the limbs, Raynauds disease, vascular migraines, and retinopathy. Nicergoline has been registered in over fifty countries and has been used for more than three decades for the treatment of cognitive, affective, and behavioral disorders of older people. Nicerogline is used in the following cases: Acute and chronic cerebral metabolic-vascular disorders (cerebral arteriosclerosis, thrombosis and cerebral embolism, transitory cerebral ischaemia). Acute and chronic peripheral metabolic-vascular disorders (organic and ...
Myricetin and Hesperidin Inhibit Cerebral Thrombogenesis and Atherogenesis in Apoe-/- and Ldlr-/- Mice
Flavonoids have been reported to possess strong antioxidant activities that moderate endothelial dysfunction and demonstrate protective effects on cardiovascular disease. Our previous studies confirmed that flavonoids, including hesperidin, naringin and nobiletin, inhibited thrombogenesis and hypertension in stroke prone spontaneously hypertensive rats (SHRSP) by protecting the endothelium from the adverse effects of free radical formation. We have now further investigated the protective effects of myricetin and hesperidin on cerebral thrombosis and atherogenesis in apolipoprotein E (apoE) and lowdensity lipoprotein receptor (LDLR) deficient (Apoe-/- and Ldlr-/- double knockout) mice. Three groups of mice were fed high fat diet alone and high fat diet mixed with myricetin (100 mg/kg/day and 200 mg/kg/day) or glucosyl hesperidin (G-hesperidin; 250 mg/kg/day and 500 mg/kg/day) for 8 weeks. There were no differences in body weight related to administration of the flavonoids. Thrombotic
Slackwares Volkerdings situation worsening? - OSnews
Cipro has very serious side effects. A brochitis infection should never have been treated with Cipro. And Cipro should never be taken as any sort of get me better antibiotic. It is really only for uses like combatting a life threatening deadly poison - such as anthrax. Unfortunately Cipro pays the reps well so you find Cipro being used where it should not be used.. My suggestion to Pat is to get more diagnosis before any long course of antibiotics, especially Cipro. It may have been the Cipro that damaged his heart in the first place:. CARDIOVASCULAR: palpitation, atrial flutter, ventricular ectopy, syncope, hypertension, angina pectoris, myocardial infarction, cardiopulmonary arrest, cerebral thrombosis, phlebitis, tachycardia, migraine, hypotension. And the general list of side effects:. SIDE EFFECTS. During clinical investigations with oral and parenteral ciprofloxacin, 49,038 patients received courses of the drug. Most of the adverse events reported were described as only mild or moderate ...
BUCHANAN, FRANK E. - Yavapai County, Arizona | FRANK E. BUCHANAN - Arizona Gravestone Photos
Frank E. BUCHANAN - Yavapai County Arizona - b. Aug. 28, 1870, Titusville, Pa. d. Jan. 27, 1956, Prescott, Az. COD: Cerebral thrombosis Widower s/o William & Artinisia (Titus) Buchanan Occ: Mining Note: Resided in Az. 54 years
Anticoagulation With Prosthetic Cardiac Valves | Valvular Heart Disease | JAMA Internal Medicine | JAMA Network
We, members of the Anticoagulation in Prosthetic Valves and Pregnancy Consensus Report (APPCR) Panel, would like to respond to the article by Ginsberg et al in
Keywords gross + vasculature + nervous system + left carotid and middle cerebral artery thrombosis | PEIR Digital Library
Welcome to the Pathology Education Informational Resource (PEIR) Digital Library, a multidisciplinary public access image database for use in medical education. ...
How a Stroke Happens?
1. Blocked Artery (causes an ischaemic stroke). A stroke that is caused by a blood clot is called an ischaemic stroke. In everyday life, blood clotting is beneficial. When you are bleeding from a wound, blood clots work to slow and eventually stop the bleeding. In the case of stroke, however, blood clots are dangerous because they can block arteries and cut off blood flow.. There are two ways an ischaemic stroke can occur.. 1.1 Embolic Stroke. If a blood clot forms somewhere in the body (usually the heart) it can travel through the bloodstream to your brain. Once in your brain, the clot travels to a blood vessel thats too small for it to pass through. It gets stuck there and stops blood from getting through. These kinds of strokes are called embolic strokes.. 1.2 Thrombotic Stroke. As the blood flows through the arteries, it may leave behind cholesterol-laden plaques that stick to the inner wall of the artery. Over time, these plaques can increase in size and narrow or block the artery and ...
TRANSIENT CEREBRAL PARALYSIS IN HYPERTENSION AND IN CEREBRAL EMBOLISM: With Special Reference to the Pathogenesis of Chronic...
A variety of cerebral attacks occur in hypertension. In cerebral hemorrhage, consciousness is lost suddenly and is not usually regained before death ensues; whe
Venoarterial cerebral perfusion for treatment of massive arterial air embolism - Fingerprint - Indiana University School...
Fingerprint Dive into the research topics of Venoarterial cerebral perfusion for treatment of massive arterial air embolism. Together they form a unique fingerprint. ...
High on Science | by M.F. Perutz | The New York Review of Books
Peter Medawar was a great biologist whose research helped to make possible the transplantation of human organs. He also thought profoundly about the methods, the meaning, and the values of scientific research, and he published his thoughts in books and essays that are models of clarity, style, and wit. Born in 1915 in Brazil of a Lebanese father and an English mother, he received his education in England and made his career there. He became a full professor at thirty-two, a Fellow of the Royal Society at thirty-four, a Nobel Laureate at forty-five, and head of Britains largest medical research laboratory at forty-seven. At fifty-four, when his intellectual powers and capacity for work seemed inexhaustible, a cerebral hemorrhage destroyed the right half of his brain, but it did not impair his determination, his vitality and optimism. Three years later he was back at his research and literary work, and he lectured around the globe. In 1980 a cerebral thrombosis set him back severely. Again he ...
Sherman, Mary Belle (1862-1935) | Encyclopedia.com
Sherman, Mary Belle (1862-1935)American clubwoman who lobbied on behalf of the national-parks movement. Born Mary Belle King on December 11, 1862, in Albion, New York; died of cerebral thrombosis on January 15, 1935; daughter of Rufus King and Sarah Electa (Whitney) King; educated at St. Source for information on Sherman, Mary Belle (1862-1935): Women in World History: A Biographical Encyclopedia dictionary.
All you need to know about a stroke - Proactive Wellness Centers
Transient ischemic attack (TIA). Sometimes, the blood supply to the brain is temporarily interrupted by a blood clot. This results in a mini-stroke, technically called transient ischemic attack. While TIA exhibits symptoms of a full stroke, these symptoms typically disappear within a few minutes to hours.. More often than not, a full stroke is usually preceded by TIA. Unfortunately, statistics by the CDC show that more than one-third of people who experience TIA and fail to receive medical attention end up having a full stroke within a year.. Ischemic stroke. Ischemic stroke is caused by the narrowing or blocking of arteries that take blood to the brain. While this blockage is primarily caused by a blood clot, it can also be caused by atherosclerosis breaking off and blocking the blood vessel.. There are two main types of ischemic stroke: embolic and thrombotic stroke. In a thrombotic stroke, a blood clot forms right in the arteries supplying the brain with blood. On the other hand, in an ...
Microembolism Medical Definition | Merriam-Webster Medical Dictionary
Medical definition of microembolism: a small embolus (as one consisting of an aggregation of platelets) that blocks an arteriole or the terminal part…
Cardiac papillary fibroelastoma: source of cerebral embolism treated with intravenous thrombolysis.
We present the case of a 41-year-old man with sudden development of left hemiparesis due to infarction of the right middle cerebral artery that was successfully treated with intravenous (IV) thrombolysis with alteplase. Transthoracic echocardiography
Clinical features and the degree of cerebrovascular stenosis in different types and subtypes of cerebral watershed infarction |...
Whether there are differences in pathogenesis among different types and subtypes of cerebral watershed infarction (WSI) is controversial since they have been combined into a single group in most previous studies. We prospectively identified 340 supratentorial WSI patients at Beijing Chao-Yang Hospital, Capital Medical University, China and classified them based on diffusion-weighted imaging(DWI) templates. Baseline characteristics, clinical courses and neuroradiological features were compared among patients with different types and subtypes of WSI. We identified 92 patients with cortical watershed infarction (CWI), 112 with internal watershed infarction (IWI) and 136 with mixed-type infarction. Compared with CWI patients, more IWI patients had critical stenosis of internal carotid artery (ICA) (P < 0.001). For the CWI group, patients with anterior watershed infarction (AWI) were more prone to critical ICA stenosis than those with posterior watershed infarction (PWI) (P = 0.011). For the IWI group,
Yetino, M., Ozeke, O., Deveci, B., Timur Selcuk, M. and Aras, D. (2006) Multichamber intracardiac thrombi associated with...
Yetino, M., Ozeke, O., Deveci, B., Timur Selcuk, M. and Aras, D. (2006) Multichamber intracardiac thrombi associated with activated protein C resistance in a patient with dilated cardiomyopathy. The International Journal of Cardiovascular Imaging, 22, 59-61.
Ischemic stroke - wikidoc
Editor-In-Chief: C. Michael Gibson, M.S., M.D.  Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S Synonyms and Keywords: Cerebrovascular accident; cerebrovascular event; CVA; cerebral emboli; brain attack; ischemic stroke ...
Embolic stroke of undetermined source
Patent foramen ovale (PFO): Deep vein thrombosis may result in paradoxical embolism in patients with PFO. About 40% of patients ... by CT or MRI that is not lacunar No major-risk cardioembolic source of embolism Absence of extracranial or intracranial ... Varicella zoster virus), thrombophilia, cancer-related thrombosis, migraine, Fabry disease and other genetic, autoimmune or ...
Thrombosis, and Vascular Biology. "Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, ... June 2014). "Thrombolysis for pulmonary embolism and risk of all-cause mortality, major bleeding, and intracranial hemorrhage: ... Wells criteria for pulmonary embolism Media related to Pulmonary embolism at Wikimedia Commons "Pulmonary Embolism". ... Thomson AJ, Greer IA (April 2015). "Thrombosis and Embolism during Pregnancy and the Puerperium, the Acute Management of (Green ...
List of MeSH codes (C10)
... intracranial embolism and thrombosis MeSH C10.228.140.300.525.400 - intracranial embolism MeSH C10.228.140.300.525.425 - ... intracranial thrombosis MeSH C10.228.140.300.525.669 - sinus thrombosis, intracranial MeSH C10.228.140.300.525.669.375 - ... lateral sinus thrombosis MeSH C10.228.140.300.525.669.750 - sagittal sinus thrombosis MeSH C10.228.140.300.535 - intracranial ... intracranial aneurysm MeSH C10.228.140.300.510.200.475 - intracranial arteriosclerosis MeSH C10.228.140.300.510.200.475.500 - ...
List of MeSH codes (C14)
... carotid artery thrombosis MeSH C14.907.253.378.300 - intracranial embolism MeSH C14.907.253.378.350 - intracranial thrombosis ... intracranial embolism and thrombosis MeSH C14.907.355.350.850.213.206 - carotid artery thrombosis MeSH C14.907.355.350.850.213. ... intracranial embolism and thrombosis MeSH C14.907.355.830.850.213.206 - carotid artery thrombosis MeSH C14.907.355.830.850.213. ... 300 - intracranial embolism MeSH C14.907.355.350.850.213.350 - intracranial thrombosis MeSH C14.907.355.350.850.213.669 - sinus ...
Between 5% and 10% of all in hospital deaths are due to pulmonary embolism (as a consequence of thrombosis). Estimates of the ... abortion ectopic pregnancy molar pregnancy pregnancy childbirth and the puerperium coronary portal vein thrombosis intracranial ... "Deep Vein Thrombosis & Pulmonary Embolism, Chapter 2, Travelers' Health". CDC. Retrieved 2016-12-25. This article incorporates ... Hospital admissions in the US for pulmonary embolism are 200,000 to 300,000 yearly. Thrombosis that develops into DVT will ...
A collapsed lung Thrombosis (myocardial infarction) - A heart attack Thromboembolism (pulmonary embolism) - A blood clot in the ... The most common non-cardiac causes are trauma, major bleeding (gastrointestinal bleeding, aortic rupture, or intracranial ... Embolism, or clotting, of the coronary arteries most commonly occurs from septic emboli secondary to endocarditis with ... Thrombolytics may cause harm but may be of benefit in those with a confirmed pulmonary embolism as the cause of arrest. ...
... which may travel to the arteries within the brain and cause an embolism. The embolism prevents blood flow to the brain, which ... Intracranial aneurysms are a leading cause of subarachnoid hemorrhage, or bleeding around the brain within the subarachnoid ... Dissections within the carotid arteries or vertebral arteries may compromise blood flow to the brain due to thrombosis, and ... Edema, or swelling, of the brain may occur which increases intracranial pressure and may result in brain herniation. A stroke ...
Infectious intracranial aneurysm
The terms septic aneurysm and septic embolism and septic arteritis are also commonly used. However, the word septic refers to ... Other common sources include cavernous sinus thrombosis, bacterial meningitis, poor dental hygiene and intravenous drug use. ... An infectious intracranial aneurysm (IIA, also called mycotic aneurysm) is a cerebral aneurysm that is caused by infection of ... At the same time, we prefer the use of a more specific and accurate heading, namely, infected intracranial aneurysm, to include ...
Intracranial hemorrhage is the accumulation of blood anywhere within the skull vault. A distinction is made between intra-axial ... There are four reasons why this might happen: Thrombosis (obstruction of a blood vessel by a blood clot forming locally) ... Embolism (obstruction due to an embolus from elsewhere in the body, see below), Systemic hypoperfusion (general decrease in ... Stam J (April 2005). "Thrombosis of the cerebral veins and sinuses" (PDF). The New England Journal of Medicine. 352 (17): 1791- ...
Central cyanosis may be due to the following causes: Central nervous system (impairing normal ventilation): Intracranial ... deep vein thrombosis) Differential cyanosis is the bluish coloration of the lower but not the upper extremity and the head. ... Pulmonary hypertension Pulmonary embolism Hypoventilation Chronic obstructive pulmonary disease, or COPD (emphysema) ...
... in the treatment of acute pulmonary embolism: a systematic review and meta-analysis". Thrombosis Research. 133 (3): 357-63. doi ... Adverse effects of alteplase include symptomatic intracranial hemorrhage and fatal intracranial hemorrhage. Angioedema is ... As of 2019, alteplase is the most commonly used medication to treat pulmonary embolism (PE). Alteplase has a short infusion ... Alteplase has also been used off-label for deep vein thrombosis, peripheral artery disease, pleural effusion in children, ...
... central retinal and branch vein thrombosis; priapism; pulmonary hypertension of embolic origin; embolism after insertion of ... Ancrod showed modest benefits but a trend toward increased intracranial haemorrhage. A clinical trial published in 2006 found ... and thrombosis. A small study compared to ancrod to heparin in preventing thrombosis when given to people undergoing arterial ... It is also indicated for the prevention of deep venous thrombosis after repair of the fractured neck of a femur. For the ...
Blood vessel disorder
There are two major types of VTE: deep-vein thrombosis (DVT) and pulmonary embolism. DVT is often found in the calf, ... Common types of aneurysm include abdominal aortic aneurysm, thoracic aortic aneurysm and intracranial aneurysm. Most types of ... Thrombosis, and Vascular Biology. 23 (12): 2155-2163. doi:10.1161/01.ATV.0000097770.66965.2A. PMID 14512371. Flather, Marcus D ... "Venous thrombosis". Nature Reviews Disease Primers. 1 (1): 15006. doi:10.1038/nrdp.2015.6. PMID 27189130. S2CID 24689285. Furie ...
... for the treatment of deep vein thrombosis and pulmonary embolism, and for the prevention of deep vein thrombosis in people ... It has similar efficacy to warfarin and is associated with a lower risk of intracranial bleeding, but unlike warfarin there is ... 2013). "Different combined oral contraceptives and the risk of venous thrombosis: systematic review and network meta-analysis ... but lower the risk of intracranial bleeding: insights from a meta-analysis and indirect treatment comparisons". PLOS ONE. 8 (10 ...
Deep vein thrombosis (DVT) prevention. DVTs may lead to pulmonary embolism (PE) in knee or hip replacement surgery patients. ... in preventing non-hemorrhagic stroke in people with atrial fibrillation and are associated with lower risk of intracranial ... "U.S. FDA Approves Eliquis (apixaban) for the Treatment of Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE), and for the ... On 13 March 2014, it was approved for the additional indication of preventing deep vein thrombosis and pulmonary embolism in ...
List of ICD-9 codes 390-459: diseases of the circulatory system
452 Portal vein thrombosis 453 Other venous embolism and thrombosis 453.4 Deep vein thrombosis, unspec. 453.41 Deep vein ... Cerebral aneurysm nonruptured 437.4 Cerebral arteritis 437.5 Moyamoya disease 437.6 Nonpyogenic thrombosis of intracranial ... thrombosis, proximal 453.42 Deep vein thrombosis, distal 453.9 Venous embolism, unspec. site 454 Varicose veins of lower ... Cerebral thrombosis without cerebral infarction 434.01 Cerebral thrombosis with cerebral infarction 434.1 Cerebral embolism ...
Targeted temperature management
The risk of deep vein thrombosis may be the most pressing medical complication. Deep vein thrombosis can be ... They have also rewarmed patients at too fast a rate, leading to spikes in intracranial pressure. Some of the new models have ... This condition may become potentially fatal if the clot travels to the lungs and causes a pulmonary embolism. Another potential ... The use of hypothermia to control intracranial pressure (ICP) after an ischemic stroke was found to be both safe and practical ...
Tissue plasminogen activator
Decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. In ischemic stroke patients, ... However a significant mortality rate was noted, mostly from intracranial haemorrhage at 7 days, but later mortality was not ... If pulmonary embolism causes severe instability due to high pressure on the heart ("massive PE") and leads to low blood ... Pulmonary embolism (blood clots that have moved to the lung arteries) is usually treated with heparin generally followed by ...
Cerebral venous sinus thrombosis
Wikimedia Commons has media related to Cerebral venous sinus thrombosis. "Intracranial venous thrombosis - Patient UK". UCH ... Diaz JM, Schiffman JS, Urban ES, Maccario M (1992). "Superior sagittal sinus thrombosis and pulmonary embolism: a syndrome ... Cerebral venous sinus thrombosis (CVST), cerebral venous and sinus thrombosis or cerebral venous thrombosis (CVT), is the ... Thrombosis of the sinuses is the main mechanism behind the increase in intracranial pressure due to decreased resorption of ...
Intracranial aneurysms are rare in childhood, with over 95% of all aneurysms occurring in adults.: 235 Incidence rates are two ... Blood clots can dislodge from the aneurysm, which can then lead to an embolism when the clot gets stuck and disrupts blood flow ... Aneurysms can also be a nidus (starting point) for clot formation (thrombosis) and embolization. As an aneurysm increases in ... Lv X, Yang H, Liu P, Li Y (February 2016). "Flow-diverter devices in the treatment of intracranial aneurysms: A meta-analysis ...
Other symptoms include those that indicate a rise in intracranial pressure caused by a large mass (due to hematoma expansion) ... A very small proportion is due to cerebral venous sinus thrombosis. Risk factors for ICH include: Hypertension ... and cerebral embolism (30%). Intracerebral hemorrhage was first distinguished from strokes due to insufficient blood flow, so ... "Brain Bleed/Hemorrhage (Intracranial Hemorrhage): Causes, Symptoms, Treatment". Naidich, Thomas P.; Castillo, Mauricio; Cha, ...
... thrombosis or embolism due to atherosclerosis of a large artery, (2) an embolism originating in the heart, (3) complete ... and vomiting usually occur more often in hemorrhagic stroke than in thrombosis because of the increased intracranial pressure ... In paradoxical embolism, a deep vein thrombosis embolizes through an atrial or ventricular septal defect in the heart into the ... Two types of thrombosis can cause stroke: Large vessel disease involves the common and internal carotid arteries, the vertebral ...
... massive pulmonary embolism or extensive deep vein thrombosis). The main complication is bleeding (which can be ... known intracranial arteriovenous malformation or previously known intracranial neoplasm Suspected recent (within 30 days) ... Massive pulmonary embolism. For the treatment of a massive pulmonary embolism, catheter-directed therapy is a safer and more ... Severe deep vein thrombosis (DVT), such as phlegmasia cerulea dolens, which threatens limb loss, or iliofemoral DVT, where ...
Transient ischemic attack
In-situ thrombosis, an obstruction that forms directly in the cerebral vasculature unlike the remote embolism previously ... CT, however, is more widely available and can be used particularly to rule out intracranial hemorrhage. Diffusion sequences can ... Embolisms can originate from multiple parts of the body. Common mechanisms of stroke and TIA: The initial clinical evaluation ... There are three major mechanisms of ischemia in the brain: embolism traveling to the brain, in situ thrombotic occlusion in the ...
... and to prevent deep vein thrombosis and pulmonary embolism in some circumstances. It appears to be as effective as warfarin in ... including intracranial bleeds, but the rate of gastrointestinal bleeding was significantly higher. Dabigatran capsules contain ... as well as deep vein thrombosis and pulmonary embolism in persons who have been treated for 5-10 days with parenteral ... valve thrombosis, stroke, and myocardial infarction) and major bleeding associated with dabigatran in this population. The most ...
Complications of traumatic brain injury
Infections within the intracranial cavity are a dangerous complication of TBI. They may occur outside of the dura mater, below ... Being unconscious and lying still for long periods can cause blood clots to form (deep venous thrombosis), which can cause ... pulmonary embolism. Other serious complications for patients who are unconscious, in a coma, or in a vegetative state include ... This in turn can create the following potential life-threatening symptoms: increased intra-cranial pressure (ICP), tachycardia ...
Approximately 36.6% of ischaemic strokes are caused by an embolism. Embolisms are an obstruction of a blood vessel in the brain ... In 21.4% of cases, ischaemic strokes are caused by thrombosis. A thrombus is a blood clot which forms in a cerebral blood ... In a similar manner to Streptokinase, Alteplase increases the risk of intracranial haemorrhage, however, mortality rate is not ... Stam, J. (2005-04-28). "Thrombosis of the Cerebral Veins and Sinuses". New England Journal of Medicine. 352 (17): 1791-1798. ...
... thrombosis or embolism due to atherosclerosis of a large artery, (2) embolism of cardiac origin, (3) occlusion of a small blood ... of intra-cranial stenting in symptomatic intracranial arterial stenosis, the rate of technical success (reduction to stenosis ... Cerebral venous sinus thrombosis. Unusual causes such as gas embolism from rapid ascents in scuba diving. Even in cases where ... The disruption to blood supply can come from many causes, including: Thrombosis (obstruction of a blood vessel by a blood clot ...
Management of atrial fibrillation
Thrombosis Research. 109 (5-6): 241-46. doi:10.1016/S0049-3848(03)00240-8. PMID 12818245. Hart RG, Pearce LA, Aguilar MI (2007 ... yet still had a similar risk of intracranial hemorrhage. The U.S. Food and Drug Administration (FDA) approved Dabigatran (" ... cardiovascular death and systemic embolism. The left atrial appendage can also be surgically amputated, sutured or stapled ... find a better method of implementing warfarin therapy without the inconvenience of regular monitoring and risk of intracranial ...
Traumatic brain injury
... and deep venous thrombosis, which can cause pulmonary embolism. Infections that can follow skull fractures and penetrating ... and raised intracranial pressure (the pressure within the skull). Intracranial pressure may rise due to swelling or a mass ... For intracranial hematomas, the collected blood may be removed using suction or forceps or it may be floated off with water. ... A traumatic brain injury (TBI), also known as an intracranial injury, is an injury to the brain caused by an external force. ...
Lanska D J, Kryscio R J (2000) Risk factors for peripartum and postpartum stroke and intracranial venous thrombosis. Stroke 31 ... Arterial occlusion may be due to thrombi, amniotic fragments or air embolism. Postpartum cerebral angiopathy is a transitory ... Kalbag R M, Woolf A L (1967) Cerebral Venous Thrombosis, with Special Reference to Primary Aseptic Thrombosis. Oxford, Oxford ... Puerperal women are liable to thrombosis, especially thrombophlebitis of the leg and pelvic veins; aseptic thrombi can also ...
Side effects of cyproterone acetate
CPA has been associated rarely with retinal vascular disorder, retinal vein thrombosis, and optic neuritis. A case report of ... Deipolyi AR, Han SJ, Parsa AT (October 2010). "Development of a symptomatic intracranial meningioma in a male-to-female ... "Venous thrombo-embolism as a complication of cross-sex hormone treatment of male-to-female transsexual subjects: a review". ... In addition, progestogens by themselves at physiological doses normally do not increase the risk of thrombosis. The Women's ...
... such as pulmonary embolism and deep venous thrombosis, with either pharmaceutical (TPA) or mechanical means. IVC filters: ... International Study of Unruptured Intracranial Aneurysms Investigators (1998-12-10). "Unruptured Intracranial Aneurysms - Risk ... Intracranial aneurysms arise in the arterial supply of the brain. Endovascular approaches to treatment include stenting and ... Vascular narrowing, thrombosis, aneurysms and pseudoaneurysms are commonly encountered complications over the life of an AVF or ...
Liver and kidney function tests are often abnormal. Thrombosis of the internal jugular vein can be displayed ... intracranial abscesses, meningitis). Production of bacterial toxins such as lipopolysaccharide leads to secretion of cytokines ... rather than the macroembolic clot burden more typical of acute pulmonary embolism, are responsible for the pulmonary findings ... "Internal Jugular Vein Thrombosis Clinical Presentation: History and Physical Examination, Complications". "Lemierre syndrome" ...
Vertebral artery dissection
... and embolism (migration) of these clots of the brain. From various lines of evidence, it appears that thrombosis and embolism ... and intracranial (the part inside the skull). Head pain occurs in 50-75% of all cases of vertebral artery dissection. It tends ... Kim YK, Schulman S (April 2009). "Cervical artery dissection: pathology, epidemiology and management". Thrombosis Research. 123 ... irregularities in the vessel wall and turbulence increase the risk of thrombosis (the formation of blood clots) ...
Case reports of deep vein thrombosis, pulmonary embolism, jaundice, intrahepatic cholestasis, and meningiomas in association ... Gruber TJ, Fabiano AJ, Deeb G, Lele SB, Fenstermaker RA (November 2011). "Intracranial meningiomas in patients with uterine ... including deep vein thrombosis, toxic reactions with impaired renal function, and mortality. Megestrol acetate is the generic ... case reviews and associated deep vein thrombosis". Consult Pharm. 18 (9): 764-73. PMID 16563066. Foitl DR, Hyman G, Lefkowitch ...
... a stroke is classified as being due to Thrombosis or embolism due to atherosclerosis of a large artery Embolism of cardiac ... While intracranial artery stenting is used for same side stroke prevention, basilar artery stenting may help to improve ... Antiplatelet drugs, such as aspirin, as well as anticoagulants, are used to help prevent blood clots and therefore embolisms, ... There are several causes of ischemia, including embolism and atherosclerosis. There are several conditions that can predispose ...
Pulmonary embolism occurs due as a result of deep vein thrombosis, in which blood clots form in the deep veins of the ... idiopathic intracranial hypertension, nonalcoholic steatohepatitis, Blount disease, slipped capital femoral epiphysis, ... Sapala, James A.; Wood, Michael H.; Schuhknecht, Michael P.; Sapala, M. Andrew (2003-12-01). "Fatal Pulmonary Embolism after ... Pulmonary embolism is another common adverse complication of bariatric surgery. ...
Animal model of ischemic stroke
I: a new experimental model of cerebral embolism in rats in which recirculation can be introduced in the ischemic area". Jpn J ... "Induction of reproducible brain infarction by photochemically initiated thrombosis". Ann Neurol. 17 (5): 497-504. doi:10.1002/ ... neck tourniquet or cuff Cardiac arrest Incomplete global ischemia Hemorrhage or hypotension Hypoxic ischemia Intracranial ... diffuse embolism . However, the quality of MCAO - and thus the volume of brain infarcts - is very variable, a fact which is ...
A meta-analysis of 13 randomised controlled trials". Thrombosis and Haemostasis. 105 (4): 579-85. doi:10.1160/TH10-11-0729. ... reduction in relative risk of developing a deep vein clot or pulmonary embolism. The beneficial effect was strongest is the ... intracranial hemorrhage, hemolytic anemia and retrolental fibroplasia. A 2003 Cochrane review concluded that vitamin E ...
Embolic and thrombotic events after COVID-19 vaccination
Other forms of thrombosis, such as the more common pulmonary embolism, may also occur. Arterial thrombosis has also been ... showing an independent association between baseline platelet count and the presence of intracranial hemorrhage. The study ... cerebral venous sinus thrombosis and thrombosis of the splanchnic veins. Cerebral venous sinus thrombosis may cause severe ... Capecchi M, Abbattista M, Martinelli I (October 2018). "Cerebral venous sinus thrombosis". Journal of Thrombosis and ...
Fibrinolytic therapy for acute embolic stroke: intravenous, intracarotid, and intra-arterial local approaches
Advanced Search Results - Public Health Image Library(PHIL)
Lateral Sinus Thrombosis | Harvard Catalyst Profiles | Harvard Catalyst
Intracranial Embolism and Thrombosis [C14.907.253.566]. *Intracranial Thrombosis [C14.907.253.566.350]. *Sinus Thrombosis, ... Sinus Thrombosis, Intracranial [C14.907.355.830.850.213.350.500]. *Lateral Sinus Thrombosis [C14.907.355.830.850.213.350.500. ... "Lateral Sinus Thrombosis" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Osteomyelitis, lateral sinus thrombosis, and temporal lobe infarction caused by infection of a percutaneous cochlear implant. ...
Science Clips - Volume 12, Issue 38, October 27, 2020
MESH TREE NUMBER CHANGES - 2008 MeSH
Intracranial Embolism C14.907.355.350.850.213.300 C14.907.355.590.213.300. Intracranial Embolism and Thrombosis C14.907.355.350 ... Intracranial Thrombosis C14.907.355.350.850.213.350 C14.907.355.590.213.350. Intradermal Tests E5.478.594.800.300. Intralaminar ... Sinus Thrombosis, Intracranial C10.228.140.300.525.669 C10.228.140.300.525.425.500. C14.907.253.566.586 C14.907.253.566.350.500 ... Embolism, Cholesterol C14.907.355.350.404 C14.907.355.350.454.500. Embolism, Paradoxical C14.907.355.350.850.400 C14.907. ...
Intracranial Embolism MeSH Thrombosis MeSH DeCS ID:. 59375 Unique ID:. D000083242 Documents indexed in the Virtual Health ... Cryptogenic Embolism Stroke Cryptogenic Embolism Strokes Cryptogenic Ischemic Strokes Cryptogenic Stroke Cryptogenic Strokes ... Embolism Stroke, Cryptogenic Ischemic Stroke, Cryptogenic Stroke, Cryptogenic Stroke, Cryptogenic Embolism Stroke, Cryptogenic ... Cryptogenic Embolism Stroke. Cryptogenic Embolism Strokes. Cryptogenic Ischemic Stroke. Cryptogenic Ischemic Strokes. ...
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IMSEAR at SEARO: Platelet functions & lipid profile within 24 hours following an attack of TIA, thrombotic & haemorrhagic...
Carotid Artery Thrombosis | Profiles RNS
Embolism and Thrombosis [C14.907.355]. *Thromboembolism [C14.907.355.590]. *Intracranial Embolism and Thrombosis [C14.907. ... "Carotid Artery Thrombosis" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... This graph shows the total number of publications written about "Carotid Artery Thrombosis" by people in this website by year, ... Below are the most recent publications written about "Carotid Artery Thrombosis" by people in Profiles. ...
Neuron<sup>™</sup> Intracranial Access System
... intracranial hemorrhage; ischemia; neurological deficits including stroke; vessel spasm, thrombosis, dissection, or perforation ... acute occlusion; air embolism; death; distal embolization; emboli; false aneurysm formation; hematoma or hemorrhage at puncture ... NEURON Intracranial Access System - Intended Use. The NEURON Intracranial Access System is intended for the introduction of ... BENCHMARK Intracranial Access System - Intended Use. The BENCHMARK Intracranial Access System is intended for the introduction ...
guidelines international network | Guidelines International Network (GIN)
Intracranial Arterial Diseases (C10.228.140.300.510, C14.907.253.560); Intracranial Embolism and Thrombosis (C10.228.140.300. ... Keywords: Head trauma; Intracranial pressure; Traumatic brain injury; Brain damage; Head injury; Head trauma; Intracranial ... 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the ... 525, C14.907.253.566, C14.907.355.590.213); Intracranial Hemorrhages (C10.228.140.300.535, C14.907.253.573, C23.550.414.913); ...
Giuliana Merati - Google Scholar
... of neutrophil activation as predictors of early incidental post-surgical pulmonary embolism in patients with intracranial ... Factor V gene mutation is a risk factor for cerebral venous thrombosis. I Martinelli, G Landi, G Merati, R Cella, A Tosetto, PM ... The G1456 to T mutation in the thrombomodulin gene is not frequent in patients with venous thrombosis. EM Faioni, G Merati, F ... gene in patirnts with myocardial infarction and deep vein thrombosis. G Merati ...
Targeted use of heparin, heparinoids, or low-molecular-weight heparin to improve outcome after acute ischaemic stroke: an...
Pesquisa | Portal Regional da BVS
Intracranial large artery embolism due to carotid thrombosis caused by a neck massager: A case report. ... BACKGROUND: There are few reported cases of intracranial large artery embolism due to carotid thrombosis caused by a neck ... Neck CTA revealed thrombosis of the bilateral common carotid arteries. Carotid ultrasound showed thrombosis in the bilateral ... Computed tomography angiography (CTA) indicated M3 segment embolism of the right middle cerebral artery. ...
EP2105436B1 - Lactam-containing compounds and derivatives thereof as factor XA inhibitors - Google Patents
201000010849 intracranial embolism Diseases 0.000 claims description 4 * 229960002009 naproxen Drugs 0.000 claims description 4 ... 206010008088 Cerebral artery embolism Diseases 0.000 claims description 4 * 206010008092 Cerebral artery thrombosis Diseases ... 206010047249 Venous thrombosis Diseases 0.000 claims description 4 * 200000000007 arterial disease Diseases 0.000 claims ... 206010003178 Arterial thrombosis Diseases 0.000 claims description 4 * 239000005528 B01AC05 - Ticlopidine Substances 0.000 ...