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Intracranial AneurysmAneurysmAneurysm, RupturedCucumisCerebral AngiographySubarachnoid HemorrhageAngiography, Digital SubtractionAneurysm, InfectedAortic AneurysmSurgical InstrumentsMagnetic Resonance AngiographyHeart AneurysmAortic Aneurysm, ThoracicAneurysm, DissectingEndovascular ProceduresRupture, SpontaneousMechanical ThrombolysisNeurosurgical ProceduresTomography, X-Ray ComputedTreatment OutcomeIliac AneurysmImaging, Three-DimensionalCerebral ArteriesCoronary AneurysmBlood Vessel ProsthesisPlatinumStentsGlasgow Outcome ScaleBlood Vessel Prosthesis ImplantationCarotid Artery, InternalVascular Surgical ProceduresBalloon OcclusionAortic RuptureAneurysm, FalseRetreatmentPosterior Cerebral ArteryRetrospective StudiesMicrosurgeryIntracranial ThrombosisAnterior Cerebral ArteryCircle of WillisPostoperative ComplicationsEquipment DesignAorta, AbdominalAngiographyCerebral RevascularizationEquipment Failure AnalysisBasilar ArteryAortographyCarotid Artery DiseasesCoated Materials, BiocompatibleCraniotomyRisk FactorsVertebral ArteryPancreatic ElastaseIntracranial Arteriovenous MalformationsRecurrenceModels, CardiovascularCerebral HemorrhageIntraoperative ComplicationsProsthesis DesignIncidental FindingsSensitivity and SpecificityPolyvinylsLoeys-Dietz SyndromeTime FactorsVasospasm, IntracranialMarfan SyndromeImage Processing, Computer-AssistedNeurologic ExaminationProspective StudiesProstheses and ImplantsOphthalmic ArteryBrain Hemorrhage, TraumaticRadiography, InterventionalIntracranial EmbolismPolycystic Kidney, Autosomal DominantCarotid Artery, Internal, DissectionForeign-Body MigrationTomography, Spiral ComputedRisk AssessmentContrast MediaMagnetic Resonance ImagingCoculture TechniquesPolyarteritis NodosaCatheterizationSubarachnoid SpaceRadiographic Image EnhancementMorbidityHematoma, Subdural, AcuteCerebrovascular CirculationBasal Ganglia HemorrhageDoxycyclineCavernous SinusMiddle Cerebral ArteryMoyamoya DiseaseIliac ArteryOculomotor Nerve DiseasesThromboembolismIncidenceDiastoleReproducibility of ResultsAminocaproatesPedigree
Intracranial Aneurysm: Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (>2.5 cm in diameter) may compress adjacent structures, including the OCULOMOTOR NERVE. (From Adams et al., Principles of Neurology, 6th ed, p841)Aneurysm: Pathological outpouching or sac-like dilatation in the wall of any blood vessel (ARTERIES or VEINS) or the heart (HEART ANEURYSM). It indicates a thin and weakened area in the wall which may later rupture. Aneurysms are classified by location, etiology, or other characteristics.Aneurysm, Ruptured: The tearing or bursting of the weakened wall of the aneurysmal sac, usually heralded by sudden worsening pain. The great danger of a ruptured aneurysm is the large amount of blood spilling into the surrounding tissues and cavities, causing HEMORRHAGIC SHOCK.Cucumis: A plant genus of the family CUCURBITACEAE, order Violales, subclass Dilleniidae best known for cucumber (CUCUMIS SATIVUS) and cantaloupe (CUCUMIS MELO). Watermelon is a different genus, CITRULLUS. Bitter melon may refer to MOMORDICA or this genus.Cerebral Angiography: Radiography of the vascular system of the brain after injection of a contrast medium.Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.Angiography, Digital Subtraction: A method of delineating blood vessels by subtracting a tissue background image from an image of tissue plus intravascular contrast material that attenuates the X-ray photons. The background image is determined from a digitized image taken a few moments before injection of the contrast material. The resulting angiogram is a high-contrast image of the vessel. This subtraction technique allows extraction of a high-intensity signal from the superimposed background information. The image is thus the result of the differential absorption of X-rays by different tissues.Aneurysm, Infected: Aneurysm due to growth of microorganisms in the arterial wall, or infection arising within preexisting arteriosclerotic aneurysms.Aortic Aneurysm: An abnormal balloon- or sac-like dilatation in the wall of AORTA.Surgical Instruments: Hand-held tools or implements used by health professionals for the performance of surgical tasks.Magnetic Resonance Angiography: Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.Heart Aneurysm: A localized bulging or dilatation in the muscle wall of a heart (MYOCARDIUM), usually in the LEFT VENTRICLE. Blood-filled aneurysms are dangerous because they may burst. Fibrous aneurysms interfere with the heart function through the loss of contractility. True aneurysm is bound by the vessel wall or cardiac wall. False aneurysms are HEMATOMA caused by myocardial rupture.Aortic Aneurysm, Thoracic: An abnormal balloon- or sac-like dilatation in the wall of the THORACIC AORTA. This proximal descending portion of aorta gives rise to the visceral and the parietal branches above the aortic hiatus at the diaphragm.Aneurysm, Dissecting: Aneurysm caused by a tear in the TUNICA INTIMA of a blood vessel leading to interstitial HEMORRHAGE, and splitting (dissecting) of the vessel wall, often involving the AORTA. Dissection between the intima and media causes luminal occlusion. Dissection at the media, or between the media and the outer adventitia causes aneurismal dilation.Endovascular Procedures: Minimally invasive procedures, diagnostic or therapeutic, performed within the BLOOD VESSELS. They may be perfomed via ANGIOSCOPY; INTERVENTIONAL MAGNETIC RESONANCE IMAGING; INTERVENTIONAL RADIOGRAPHY; or INTERVENTIONAL ULTRASONOGRAPHY.Rupture, Spontaneous: Tear or break of an organ, vessel or other soft part of the body, occurring in the absence of external force.Mechanical Thrombolysis: Procedures to cause the disintegration of THROMBI by physical interventions.Neurosurgical Procedures: Surgery performed on the nervous system or its parts.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Iliac Aneurysm: Abnormal balloon- or sac-like dilatation in the wall of any one of the iliac arteries including the common, the internal, or the external ILIAC ARTERY.Imaging, Three-Dimensional: The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.Cerebral Arteries: The arterial blood vessels supplying the CEREBRUM.Coronary Aneurysm: Abnormal balloon- or sac-like dilatation in the wall of CORONARY VESSELS. Most coronary aneurysms are due to CORONARY ATHEROSCLEROSIS, and the rest are due to inflammatory diseases, such as KAWASAKI DISEASE.Blood Vessel Prosthesis: Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels.Platinum: Platinum. A heavy, soft, whitish metal, resembling tin, atomic number 78, atomic weight 195.09, symbol Pt. (From Dorland, 28th ed) It is used in manufacturing equipment for laboratory and industrial use. It occurs as a black powder (platinum black) and as a spongy substance (spongy platinum) and may have been known in Pliny's time as "alutiae".Stents: Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.Glasgow Outcome Scale: A scale that assesses the outcome of serious craniocerebral injuries, based on the level of regained social functioning.Blood Vessel Prosthesis Implantation: Surgical insertion of BLOOD VESSEL PROSTHESES to repair injured or diseased blood vessels.Carotid Artery, Internal: Branch of the common carotid artery which supplies the anterior part of the brain, the eye and its appendages, the forehead and nose.Vascular Surgical Procedures: Operative procedures for the treatment of vascular disorders.Balloon Occlusion: Use of a balloon CATHETER to block the flow of blood through an artery or vein.Aortic Rupture: The tearing or bursting of the wall along any portion of the AORTA, such as thoracic or abdominal. It may result from the rupture of an aneurysm or it may be due to TRAUMA.Aneurysm, False: Not an aneurysm but a well-defined collection of blood and CONNECTIVE TISSUE outside the wall of a blood vessel or the heart. It is the containment of a ruptured blood vessel or heart, such as sealing a rupture of the left ventricle. False aneurysm is formed by organized THROMBUS and HEMATOMA in surrounding tissue.Retreatment: The therapy of the same disease in a patient, with the same agent or procedure repeated after initial treatment, or with an additional or alternate measure or follow-up. It does not include therapy which requires more than one administration of a therapeutic agent or regimen. Retreatment is often used with reference to a different modality when the original one was inadequate, harmful, or unsuccessful.Posterior Cerebral Artery: Artery formed by the bifurcation of the BASILAR ARTERY. Branches of the posterior cerebral artery supply portions of the OCCIPITAL LOBE; PARIETAL LOBE; inferior temporal gyrus, brainstem, and CHOROID PLEXUS.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Microsurgery: The performance of surgical procedures with the aid of a microscope.Intracranial Thrombosis: Formation or presence of a blood clot (THROMBUS) in a blood vessel within the SKULL. Intracranial thrombosis can lead to thrombotic occlusions and BRAIN INFARCTION. The majority of the thrombotic occlusions are associated with ATHEROSCLEROSIS.Anterior Cerebral Artery: Artery formed by the bifurcation of the internal carotid artery (CAROTID ARTERY, INTERNAL). Branches of the anterior cerebral artery supply the CAUDATE NUCLEUS; INTERNAL CAPSULE; PUTAMEN; SEPTAL NUCLEI; GYRUS CINGULI; and surfaces of the FRONTAL LOBE and PARIETAL LOBE.Circle of Willis: A polygonal anastomosis at the base of the brain formed by the internal carotid (CAROTID ARTERY, INTERNAL), proximal parts of the anterior, middle, and posterior cerebral arteries (ANTERIOR CEREBRAL ARTERY; MIDDLE CEREBRAL ARTERY; POSTERIOR CEREBRAL ARTERY), the anterior communicating artery and the posterior communicating arteries.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Equipment Design: Methods of creating machines and devices.Aorta, Abdominal: The aorta from the DIAPHRAGM to the bifurcation into the right and left common iliac arteries.Angiography: Radiography of blood vessels after injection of a contrast medium.Cerebral Revascularization: Microsurgical revascularization to improve intracranial circulation. It usually involves joining the extracranial circulation to the intracranial circulation but may include extracranial revascularization (e.g., subclavian-vertebral artery bypass, subclavian-external carotid artery bypass). It is performed by joining two arteries (direct anastomosis or use of graft) or by free autologous transplantation of highly vascularized tissue to the surface of the brain.Equipment Failure Analysis: The evaluation of incidents involving the loss of function of a device. These evaluations are used for a variety of purposes such as to determine the failure rates, the causes of failures, costs of failures, and the reliability and maintainability of devices.Basilar Artery: The artery formed by the union of the right and left vertebral arteries; it runs from the lower to the upper border of the pons, where it bifurcates into the two posterior cerebral arteries.Aortography: Radiographic visualization of the aorta and its branches by injection of contrast media, using percutaneous puncture or catheterization procedures.Carotid Artery Diseases: Pathological conditions involving the CAROTID ARTERIES, including the common, internal, and external carotid arteries. ATHEROSCLEROSIS and TRAUMA are relatively frequent causes of carotid artery pathology.Coated Materials, Biocompatible: Biocompatible materials usually used in dental and bone implants that enhance biologic fixation, thereby increasing the bond strength between the coated material and bone, and minimize possible biological effects that may result from the implant itself.Craniotomy: Any operation on the cranium or incision into the cranium. (Dorland, 28th ed)Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Vertebral Artery: The first branch of the SUBCLAVIAN ARTERY with distribution to muscles of the NECK; VERTEBRAE; SPINAL CORD; CEREBELLUM; and interior of the CEREBRUM.Pancreatic Elastase: A protease of broad specificity, obtained from dried pancreas. Molecular weight is approximately 25,000. The enzyme breaks down elastin, the specific protein of elastic fibers, and digests other proteins such as fibrin, hemoglobin, and albumin. EC 3.4.21.36.Intracranial Arteriovenous Malformations: Congenital vascular anomalies in the brain characterized by direct communication between an artery and a vein without passing through the CAPILLARIES. The locations and size of the shunts determine the symptoms including HEADACHES; SEIZURES; STROKE; INTRACRANIAL HEMORRHAGES; mass effect; and vascular steal effect.Recurrence: The return of a sign, symptom, or disease after a remission.Models, Cardiovascular: Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.Cerebral Hemorrhage: Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA.Intraoperative Complications: Complications that affect patients during surgery. They may or may not be associated with the disease for which the surgery is done, or within the same surgical procedure.Prosthesis Design: The plan and delineation of prostheses in general or a specific prosthesis.Incidental Findings: Unanticipated information discovered in the course of testing or medical care. Used in discussions of information that may have social or psychological consequences, such as when it is learned that a child's biological father is someone other than the putative father, or that a person tested for one disease or disorder has, or is at risk for, something else.Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)PolyvinylsLoeys-Dietz Syndrome: An autosomal dominant aneurysm with multisystem abnormalities caused by increased TGF-BETA signaling due to mutations in type I or II of TGF-BETA RECEPTOR. Additional craniofacial features include CLEFT PALATE; CRANIOSYNOSTOSIS; HYPERTELORISM; or bifid uvula. Phenotypes closely resemble MARFAN SYNDROME; Marfanoid craniosynostosis syndrome (Shprintzen-Goldberg syndrome); and EHLERS-DANLOS SYNDROME.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Vasospasm, Intracranial: Constriction of arteries in the SKULL due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and BRAIN ISCHEMIA that may lead to hypoxic-ischemic brain injury (HYPOXIA-ISCHEMIA, BRAIN).Marfan Syndrome: An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome is associated with mutations in the gene encoding fibrillin, a major element of extracellular microfibrils of connective tissue.Image Processing, Computer-Assisted: A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.Neurologic Examination: Assessment of sensory and motor responses and reflexes that is used to determine impairment of the nervous system.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Prostheses and Implants: Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally.Ophthalmic Artery: Artery originating from the internal carotid artery and distributing to the eye, orbit and adjacent facial structures.Brain Hemorrhage, Traumatic: Bleeding within the brain as a result of penetrating and nonpenetrating CRANIOCEREBRAL TRAUMA. Traumatically induced hemorrhages may occur in any area of the brain, including the CEREBRUM; BRAIN STEM (see BRAIN STEM HEMORRHAGE, TRAUMATIC); and CEREBELLUM.Radiography, Interventional: Diagnostic and therapeutic procedures that are invasive or surgical in nature, and require the expertise of a specially trained radiologist. In general, they are more invasive than diagnostic imaging but less invasive than major surgery. They often involve catheterization, fluoroscopy, or computed tomography. Some examples include percutaneous transhepatic cholangiography, percutaneous transthoracic biopsy, balloon angioplasty, and arterial embolization.Intracranial Embolism: Blocking of a blood vessel in the SKULL by an EMBOLUS which can be a blood clot (THROMBUS) or other undissolved material in the blood stream. Most emboli are of cardiac origin and are associated with HEART DISEASES. Other non-cardiac sources of emboli are usually associated with VASCULAR DISEASES.Polycystic Kidney, Autosomal Dominant: Kidney disorders with autosomal dominant inheritance and characterized by multiple CYSTS in both KIDNEYS with progressive deterioration of renal function.Carotid Artery, Internal, Dissection: The splitting of the vessel wall in one or both (left and right) internal carotid arteries (CAROTID ARTERY, INTERNAL). Interstitial hemorrhage into the media of the vessel wall can lead to occlusion of the internal carotid artery and aneurysm formation.Foreign-Body Migration: Migration of a foreign body from its original location to some other location in the body.Tomography, Spiral Computed: Computed tomography where there is continuous X-ray exposure to the patient while being transported in a spiral or helical pattern through the beam of irradiation. This provides improved three-dimensional contrast and spatial resolution compared to conventional computed tomography, where data is obtained and computed from individual sequential exposures.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Contrast Media: Substances used to allow enhanced visualization of tissues.Magnetic Resonance Imaging: Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.Coculture Techniques: A technique of culturing mixed cell types in vitro to allow their synergistic or antagonistic interactions, such as on CELL DIFFERENTIATION or APOPTOSIS. Coculture can be of different types of cells, tissues, or organs from normal or disease states.Polyarteritis Nodosa: A form of necrotizing non-granulomatous inflammation occurring primarily in medium-sized ARTERIES, often with microaneurysms. It is characterized by muscle, joint, and abdominal pain resulting from arterial infarction and scarring in affected organs. Polyarteritis nodosa with lung involvement is called CHURG-STRAUSS SYNDROME.Catheterization: Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.Subarachnoid Space: The space between the arachnoid membrane and PIA MATER, filled with CEREBROSPINAL FLUID. It contains large blood vessels that supply the BRAIN and SPINAL CORD.Radiographic Image Enhancement: Improvement in the quality of an x-ray image by use of an intensifying screen, tube, or filter and by optimum exposure techniques. Digital processing methods are often employed.Morbidity: The proportion of patients with a particular disease during a given year per given unit of population.Hematoma, Subdural, Acute: Accumulation of blood in the SUBDURAL SPACE with acute onset of neurological symptoms. Symptoms may include loss of consciousness, severe HEADACHE, and deteriorating mental status.Cerebrovascular Circulation: The circulation of blood through the BLOOD VESSELS of the BRAIN.Basal Ganglia Hemorrhage: Bleeding within the subcortical regions of cerebral hemispheres (BASAL GANGLIA). It is often associated with HYPERTENSION or ARTERIOVENOUS MALFORMATIONS. Clinical manifestations may include HEADACHE; DYSKINESIAS; and HEMIPARESIS.Doxycycline: A synthetic tetracycline derivative with similar antimicrobial activity.Cavernous Sinus: An irregularly shaped venous space in the dura mater at either side of the sphenoid bone.Middle Cerebral Artery: The largest of the cerebral arteries. It trifurcates into temporal, frontal, and parietal branches supplying blood to most of the parenchyma of these lobes in the CEREBRAL CORTEX. These are the areas involved in motor, sensory, and speech activities.Moyamoya Disease: A noninflammatory, progressive occlusion of the intracranial CAROTID ARTERIES and the formation of netlike collateral arteries arising from the CIRCLE OF WILLIS. Cerebral angiogram shows the puff-of-smoke (moyamoya) collaterals at the base of the brain. It is characterized by endothelial HYPERPLASIA and FIBROSIS with thickening of arterial walls. This disease primarily affects children but can also occur in adults.Iliac Artery: Either of two large arteries originating from the abdominal aorta; they supply blood to the pelvis, abdominal wall and legs.Oculomotor Nerve Diseases: Diseases of the oculomotor nerve or nucleus that result in weakness or paralysis of the superior rectus, inferior rectus, medial rectus, inferior oblique, or levator palpebrae muscles, or impaired parasympathetic innervation to the pupil. With a complete oculomotor palsy, the eyelid will be paralyzed, the eye will be in an abducted and inferior position, and the pupil will be markedly dilated. Commonly associated conditions include neoplasms, CRANIOCEREBRAL TRAUMA, ischemia (especially in association with DIABETES MELLITUS), and aneurysmal compression. (From Adams et al., Principles of Neurology, 6th ed, p270)Thromboembolism: Obstruction of a blood vessel (embolism) by a blood clot (THROMBUS) in the blood stream.Incidence: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.Diastole: Post-systolic relaxation of the HEART, especially the HEART VENTRICLES.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Aminocaproates: Amino derivatives of caproic acid. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the amino caproic acid structure.Pedigree: The record of descent or ancestry, particularly of a particular condition or trait, indicating individual family members, their relationships, and their status with respect to the trait or condition.

3D angiography. Clinical interest. First applications in interventional neuroradiology. (1/2536)

3D angiography is a true technical revolution that allows improvement in the quality and safety of diagnostic and endovascular treatment procedures. 3D angiography images are obtained by reconstruction of a rotational angiography acquisition done on a C-arm (GE Medical Systems) spinning at 40 degrees per second. The carotid or vertebral selective injection of a total of 15 ml of non-ionic contrast media at 3 ml/sec over 5 seconds allows the selection of the "arterial phase". Four hundred sixty 3D angiographic studies were performed from December 1996 to September 1998 on 260 patients and have been analyzed in MIP (Maximum Intensity Projection) and SSD (Shaded Surface Display) views. The exploration of intracranial aneurysms is simplified and only requires, for each vascular axis, a biplane PA and Lateral run followed by a single rotational angiography run. The 3D angiography image is available on the workstation's screen (Advantage Workstation 3.1, GE Medical Systems) in less than 10 minutes after the acquisition of the rotational run. It therefore allows one to analyze, during the intervention, the aneurysm's angioarchitecture, in particular the neck, and select the best therapeutic technique. When endovascular treatment is the best indication, 3D angiography allows one to define the optimal angle of view and accurately select the microcoils dimensions. 3D angiography replaces the multiple oblique views that used to be required to analyze the complex aneurysms and therefore allows a reduction of the total contrast medium quantity, the patient X-ray dose and the length of the intervention time which is a safety factor. Also, in particular for complex cases, it brings additional elements complementing the results of standard 2D DSA and rotational angiograms. In the cervical vascular pathology, 3D angiography allows for a better assessment of the stenosis level and of dissection lesions. Our current research activities focus on the matching without stereotactic frame between 3D X-ray angiography and volumetric MR acquisition, which should allow us to improve the treatment of intracerebral arterio-venous malformations (AVMs).  (+info)

Combination therapy of fasudil hydrochloride and ozagrel sodium for cerebral vasospasm following aneurysmal subarachnoid hemorrhage. (2/2536)

Fasudil hydrochloride is a new type of intracellular calcium antagonist, different from the calcium entry blockers that are commonly employed for clinical use. Since September 1995, the combination of fasudil hydrochloride and ozagrel sodium, an inhibitor of thromboxane A2 synthesis, has been used to treat 60 patients at risk of cerebral vasospasm after aneurysmal subarachnoid hemorrhage. The effectiveness of this combination therapy was investigated by comparison with the outcome of 57 patients previously treated with only ozagrel sodium. The combination therapy was significantly more effective (p < 0.01) in reducing the incidence of low density areas on computed tomography scans, and reduced, but not significantly, the occurrence of symptomatic vasospasm. The combination therapy of fasudil hydrochloride and ozagrel sodium has superior effectiveness over only ozagrel sodium in treating patients at risk of vasospasm after aneurysmal subarachnoid hemorrhage.  (+info)

Large and giant middle to lower basilar trunk aneurysms treated by surgical and interventional neuroradiological methods. (3/2536)

Treatment of large and giant aneurysms of the basilar artery remains difficult and controversial. Three large or giant aneurysms of the lower basilar artery were treated with a combination of surgical and interventional neuroradiological procedures. All patients underwent the balloon occlusion test with hypotensive challenge (blood pressure reduced to 70% of the control value). The third patient did not tolerate the test. In the first patient, both vertebral arteries were occluded through a craniotomy. In the second patient, both the aneurysm and the basilar artery were occluded by detached balloons. In the third patient, one vertebral artery was occluded by surgical clipping and the other by detached helical coils and fiber coils. In spite of anti-coagulation and anti-platelet therapy, postoperative thrombotic or embolic ischemia occurred in the second and third patients. Fibrinolytic therapy promptly corrected the ischemic symptoms, but the second patient developed hemorrhagic complications at the craniotomy area 2 hours later. At follow-up examination, the first patient had only 8th cranial nerve paresis, the second patient who had a hemorrhagic complication was bed-ridden, and the third patient had no deficit. Interventional occlusion requires a longer segment of the parent artery compared to surgical occlusion of the parent artery and might cause occlusion of the perforating arteries. However, selected use of various coils can occlude only a short segment of the parent artery. Thus, the postoperative management of thromboembolic ischemia after the occlusion of the parent artery is easier using the interventional technique.  (+info)

Significance of acute cerebral swelling in patients with sylvian hematoma due to ruptured middle cerebral artery aneurysm, and its management. (4/2536)

A retrospective study of 75 patients treated surgically for ruptured middle cerebral artery (MCA) aneurysm within 48 hours evaluated clinical grade at admission, secondary development and management of cerebral swelling associated with space-occupying hematoma, cerebral infarction caused by vasospasm, development of hydrocephalus, and clinical outcome. Clinical grade at admission was significantly better in patients without than in those with hematoma (p < 0.01). Twenty-seven patients with sylvian hematoma caused by ruptured MCA aneurysm often developed ipsilateral cerebral swelling in the early period after subarachnoid hemorrhage. Seventeen of these patients developed serious cerebral swelling and received barbiturate therapy. Nine of these 17 patients had good outcome, but six patients died of cerebral swelling. The incidence of hydrocephalus was significantly higher in patients with than in those without hematoma (p < 0.01). The incidence of infarction was more pronounced in patients with sylvian hematoma. Clinical outcome was significantly better in patients without than in those with sylvian hematoma (p < 0.01). Development of cerebral swelling in patients with sylvian hematoma due to ruptured MCA aneurysm has a significant effect on outcome, and improvements in management are required.  (+info)

Rupture mechanism of a thrombosed slow-growing giant aneurysm of the vertebral artery--case report. (5/2536)

A 76-year-old male developed left hemiparesis in July 1991. The diagnosis was thrombosed giant vertebral artery aneurysm. He showed progressive symptoms and signs of brainstem compression, but refused surgery and was followed up without treatment. He died of rupture of the aneurysm and underwent autopsy in March 1995. Histological examination of the aneurysm revealed fresh clot in the aneurysmal lumen, old thrombus surrounding the aneurysmal lumen, and more recent hemorrhage between the old thrombus and the inner aneurysmal wall. The most important histological feature was the many clefts containing fresh blood clots in the old thrombus near the wall of the distal neck. These clefts were not lined with endothelial cells, and seemed to connect the lumen of the parent artery with the most peripheral fresh hemorrhage. However, the diameter of each of these clefts is apparently not large enough to transmit the blood pressure of the parent artery. Simple dissection of the aneurysmal wall by blood flow in the lumen through many clefts in the old thrombus of the distal neck may be involved in the growth and rupture of thrombosed giant aneurysms of the vertebral artery.  (+info)

Primary non-traumatic intracranial hemorrhage. A municipal emergency hospital viewpoint. (6/2536)

The devastating natural history of 138 consecutive admissions for non-traumatic intracranial hemorrhage to a major emergency care municipal hospital is reviewed. Sixty-four percent of the patients had demonstrable intracranial hematomas while 36% had mainly subarachnoid hemorrhage. Hypertension was a related condition in 43% of the parenchymal hematoma patients, while proved aneurysms accounted for 74% of the subarachnoid hemorrhage patients. There was only a 14% survivorship for patients requiring emergent surgery. All operated hematoma patients survived delayed surgery with improved level of responsiveness. The overall mortality was 74% for intracranial hematoma patients and 58% for aneurysm-caused subarachnoid hemorrhage patients.  (+info)

The use of electrophysiological monitoring in the intraoperative management of intracranial aneurysms. (7/2536)

OBJECTIVES: Somatosensory evoked potentials (SSEPs) and brainstem auditory evoked potentials (BAEPs) have been increasingly utilised during surgery for intracranial aneurysms to identify cerebral ischaemia. Between July 1994 and April 1996, we surgically treated 70 aneurysms in 49 consecutive patients (58 operations) with the aid of intraoperative evoked potential monitoring. This study sought to evaluate the usefulness of SSEP and BAEP monitoring during intracranial aneurysm surgery. METHODS: Mean patient age was 51.9 (range 18-79) years. The sizes of the aneurysms were 3-4 mm (15), 5-9 mm (26), 10-14 mm (11), 15-19 mm (seven), 20-24 mm (six), and >25 mm (five). SSEPs were monitored in 58 procedures (100%) and BAEPs in 15 (26%). The neurological status of the patients was evaluated before and after surgery. RESULTS: Thirteen of the 58 procedures (22%) monitored with SSEPs had SSEP changes (12 transient, one persistent); 45 (78%) had no SSEP changes. Three of 15 patients (20%) monitored with BAEPs had changes (two transient, one persistent); 12 (80%) had no BAEP changes. Of the 14 patients with transient SSEP or BAEP changes, these changes resolved with adjustment or removal of aneurysm clips (nine), elevating MAP (four), or retractor adjustment (one). Mean time from precipitating event to electrophysiological change was 8.9 minutes (range 3-32), and the mean time for recovery of potentials in patients with transient changes was 20.2 minutes (range 3-60). Clinical outcome was excellent in 39 patients, good in five, and poor in three (two patients died), and was largely related to pretreatment grade. CONCLUSIONS: SSEPs and BAEPs are useful in preventing clinical neurological injury during surgery for intracranial aneurysms and in predicting which patients will have unfavourable outcomes.  (+info)

Cerebral arterial lesions resulting from inflammatory emboli. (8/2536)

In order to study the effects of septic embolism on the brain, silicone rubber emboli of various types were injected into the carotid arteries of 35 dogs. Pathologic and angiographic studies were performed to assess the resultant arterial and parenchymal lesions. Pure silicone rubber emboli (14 dogs) produced occasional intra-arterial thrombosis but no arteritis. Sterile and bacterially contaminated emboli containing a lead-chromate pigment (similar to those used in previous studies of septic embolism) (11 dogs) and pure silicone rubber emboli with transversely oriented canals (10 dogs), after brief placement in a bacterial suspension, were associated with intense inflammatory arteritis. This was accompanied by focal meningitis, subarachnoid hemorrhage, thrombosis, and cerebritis of the underlying cortex. The findings resembled those found in mycotic aneurysm. Aneurysmal dilatation was observed in one postmortem angiogram. In previous models of mycotic aneurysm, the inflammation attributed to bacterial contamination was probably due to the lead-chromate pigment used.  (+info)

Familial Intracranial Aneurysm Study II - Full Text View - ClinicalTrials.govFamilial Intracranial Aneurysm Study II - Full Text View - ClinicalTrials.gov
Intracranial aneurysms are blisters which form within the arteries at the base of the brain. A rupture of an aneurysm may lead to subarachnoid hemorrhage (SAH). The mortality rates of patients suffering from a SAH is 40 to 44 percent , with many survivors enduring major disability. Most of the deaths from SAH are due to rapid and massive brain injury from the initial bleeding, which is not correctable by medical and surgical intervention. Thus, prevention of aneurysm formation is of paramount importance.. Scientific evidence suggests that a genetic component plays an important role in the development of intracranial aneurysms, however the specific genes have not been identified. The Familial Intracranial Aneurysm Study is a collaborative research effort of neurologists and neurosurgeons throughout the United States, Canada, Australia and New Zealand to identify possible genes that may increase the risk of stroke, and particularly, the development of aneurysms in the blood vessels of the brain. ...
Risk-benefit analysis of the treatment of unruptured intracranial aneurysmsRisk-benefit analysis of the treatment of unruptured intracranial aneurysms
Objectives: To determine under what circumstances repair of unruptured intracranial aneurysms may be beneficial. Methods: A life expectancy analysis of patients with unruptured aneurysms with and without repair based on prospective data from the International Study of Unruptured Intracranial Aneurysms (ISUIA). Results: Life years are lost at all ages by repairing anterior circulation aneurysms under 7 mm in diameter in patients with no history of a subarachnoid haemorrhage from another aneurysm (incidental). For all other aneurysms the number of life years saved by repair is dependent on the patients age at the time when repair is undertaken. Between 2 and 40 years are saved by repairing aneurysms in patients aged 20 years. These benefits fall to 0 when remaining life expectancy falls below 15-35 years, corresponding to the age range of 45-70 years. Conclusions: Repair of unruptured aneurysms benefits patients harbouring them by improving life expectancy except in certain circumstances. The ...
Themodernmaven.biz :: How To Treat A Brain AneurysmThemodernmaven.biz :: How To Treat A Brain Aneurysm
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Intracranial aneurysm - WikipediaIntracranial aneurysm - Wikipedia
Intracranial aneurysm, also known as brain aneurysm, is a cerebrovascular disorder in which weakness in the wall of a cerebral artery or vein causes a localized dilation or ballooning of the blood vessel. Aneurysms in the posterior circulation (basilar artery, vertebral arteries and posterior communicating artery) have a higher risk of rupture. Basilar artery aneurysms represent only 3%-5% of all intracranial aneurysms but are the most common aneurysms in the posterior circulation. Cerebral aneurysms are classified both by size and shape. Small aneurysms have a diameter of less than 15 mm. Larger aneurysms include those classified as large (15 to 25 mm), giant (25 to 50 mm), and super-giant (over 50 mm). Saccular aneurysms, also known as berry aneurysms, appear as a round outpouching and are the most common form of cerebral aneurysm. Fusiform dolichoectatic aneurysms represent a widening of a segment of an artery around the entire blood vessel, rather than just arising from a side of an arterys ...
Apolipoprotein E polymorphism and the risk of intracranial aneurysms in a Chinese population | BMC Neurology | Full TextApolipoprotein E polymorphism and the risk of intracranial aneurysms in a Chinese population | BMC Neurology | Full Text
Although lot of studies have been conducted to examine the association of genetic polymorphism and intracranial aneurysms, the relationship between the APOE polymorphism and intracranial aneurysms has previously only been studied in Russia and Japan but not in Chinese populations [13, 14]. Evidence from a case-control study suggested that the collagen type I alpha2 gene polymorphism was associated with intracranial aneurysms in a subset of the German population [15]. Authors of a case-control study suggested that the IL-12A and IL-12B independently and jointly was involved in the susceptibility to intracranial aneurysms in a Chinese population [16]. Evidence from a meta-analysis included six case-control studies, which included 1188 intracranial aneurysms cases and 4099 controls, suggested that IL-6 promoter polymorphisms (-174G/C and -572G/C) were associated with intracranial aneurysms [17]. Authors of a case-control study in a Chinese population suggested that the miR-34b/c rs4938723CC and ...
North Shore University Hospitals Brain Aneurysm Center Offers New Pipeline® Embolization Device to Treat Complex Brain...North Shore University Hospital's Brain Aneurysm Center Offers New Pipeline® Embolization Device to Treat Complex Brain...
The PED is a flexible, braided wire mesh tube which can be placed within the internal carotid artery in the brain, blocking off large or wide-necked aneurysms. The device can also reduce the likelihood that an aneurysm will rupture. "The Pipeline® Embolization Device offers neurointerventional surgeons a minimally invasive alternative to open surgery or placement of materials such as coils or a liquid embolic when treating carotid artery brain aneurysms," said Avi Setton, MD, chief of interventional neuroradiology at North Shore University Hospital. "While coiling can be effective for small brain aneurysms, it does not always work on larger ones. The PED device offers patients a better chance of long-lasting aneurysm occlusion and low complication rates.". In the endovascular procedure, the PED is threaded up through a catheter placed in a blood vessel in the leg, up to the brain. The PED is implanted across the neck of the aneurysm, cutting off blood flow. The blood that remains in the ...
International Retrospective Study of the Pipeline Embolization Device: A Multicenter Aneurysm Treatment Study | American...International Retrospective Study of the Pipeline Embolization Device: A Multicenter Aneurysm Treatment Study | American...
This large multicenter study of flow-diversion therapy demonstrated a neurologic morbidity and mortality rate of 8.4%. Most adverse events were ischemic strokes from thromboembolic complications and were substantially more common in large, anterior circulation aneurysms and posterior circulation aneurysms compared with small, anterior circulation aneurysms. Spontaneous aneurysm rupture was rare, occurring in 0.6% of patients, with 3/5 events occurring within giant aneurysms. Intraparenchymal hemorrhage, unrelated to rupture of the target aneurysm but resulting in major neurologic deficit, was noted in 2.4% of patients. These results are important because they provide clarity regarding the previously noted severe and unexpected adverse events associated with flow-diversion therapy in a real-world setting. Our data suggest strongly that spontaneous aneurysm rupture is not of clinical concern in non-giant aneurysms. Parenchymal hemorrhage remains of concern, especially because its etiology is ...
Risk of Rupture of an Intracranial Aneurysm Based on Patient Characteristics | StrokeRisk of Rupture of an Intracranial Aneurysm Based on Patient Characteristics | Stroke
Methods-We performed a case-control study with 250 patients with an aneurysmal subarachnoid hemorrhage and 206 patients with an unruptured intracranial aneurysm. All patients with an aneurysmal subarachnoid hemorrhage and patients with a unruptured intracranial aneurysm were asked to fill in a structured questionnaire about their lifestyle and medical history. For patients with an unruptured intracranial aneurysm, we also collected data on the indication for imaging. With logistic regression analysis, we identified independent risk factors for aneurysmal rupture.. ...
Treatment of Cranial Internal Carotid Artery Aneurysm With Willis Covered Stent and Coil Embolization - Full Text View -...Treatment of Cranial Internal Carotid Artery Aneurysm With Willis Covered Stent and Coil Embolization - Full Text View -...
Endovascular treatment of intracranial aneurysms with detachable coils has been widely used since the introduction of GDCs in 1991 and has been proven to be effective in preventing rebleeding after aneurysmal rupture. The clinical and angiographic results of endovascular coil occlusion of intracranial aneurysms are positive, with an initial and final overall complete occlusion rate of 35.9%-76.8% and 38.3%- 87.8%. In the mid- and long-term, however, aneurysm recanalization may occur in as many as one-third of cases.. The natural history of aneurysm recurrence after coil treatment is often benign, but bleeding from incompletely coiled aneurysms is a well-documented threat, moreover, the degree of aneurysm occlusion after treatment was strongly associated with risk of rerupture. Even if 100% occlusion of the aneurysms after the initial treatment was obtained on immediate postembolization angiography, there was still a relatively high recanalization rate (26.4%) on long-term follow-up angiography. ...
Common Data Elements for Unruptured Intracranial Aneurysms and Subarachnoid Hemorrhage Clinical Research: A National Institute...Common Data Elements for Unruptured Intracranial Aneurysms and Subarachnoid Hemorrhage Clinical Research: A National Institute...
TY - JOUR. T1 - Common Data Elements for Unruptured Intracranial Aneurysms and Subarachnoid Hemorrhage Clinical Research. T2 - A National Institute for Neurological Disorders and Stroke and National Library of Medicine Project. AU - the Unruptured Intracranial Aneurysms and SAH CDE Project Investigators. AU - Suarez, Jose I.. AU - Sheikh, Muniza K.. AU - Macdonald, R. Loch. AU - Amin-Hanjani, Sepideh. AU - Brown, Robert D.. AU - de Oliveira Manoel, Airton Leonardo. AU - Derdeyn, Colin P.. AU - Etminan, Nima. AU - Keller, Emanuela. AU - Leroux, Peter D.. AU - Mayer, Stephan A.. AU - Morita, Akio. AU - Rinkel, Gabriel. AU - Rufennacht, Daniel. AU - Stienen, Martin N.. AU - Torner, James. AU - Vergouwen, Mervyn D.I.. AU - Wong, George K.C.. AU - Mayer, Stephan. AU - Bijlenga, Philippe. AU - Ko, Nerissa. AU - McDougall, Cameron G.. AU - Mocco, J.. AU - Murayama, Yuuichi. AU - Werner, Marieke J.H.. AU - Broderick, Joseph. AU - Dhar, Raj. AU - Jauch, Edward C.. AU - Kirkpatrick, Peter J.. AU - Martin, ...
Intraoperative microvascular Doppler in intracranial aneurysm surgery. | IRIS Università degli Studi di PadovaIntraoperative microvascular Doppler in intracranial aneurysm surgery. | IRIS Università degli Studi di Padova
OBJECTIVE: The usefulness of intraoperative microvascular Doppler (IMD) in preventing an incorrect placement of the clip during intracranial aneurysm surgery is described. Such incorrect placement of the clip may cause new bleeding or ischemic accident as a consequence of incomplete exclusion of the aneurysm or stenosis/occlusion of the parent and/or adjacent arteries. METHODS: One hundred thirty patients, harboring 136 aneurysms, were operated on using IMD. IMD study was performed on the aneurysm and adjacent arterial vessels before and after the clip placement. Mechanical arterial spasm was treated by topical sodium nitroprusside (SNP) and its efficacy verified by IMD. RESULTS: In 55 aneurysms (42.3%), IMD was helpful in understanding the microvascular anatomy before clip placement. Complete exclusion resulted in 129 aneurysms (94.9%). In 5 cases (3.7%) in which IMD revealed a persistent blood flow in the aneurysm, the clip was repositioned. In 2 cases (1.4%), we obtained false-negative ...
Adenosine for temporary flow arrest during intracranial aneurysm surgery: A single-center retrospective review<...Adenosine for temporary flow arrest during intracranial aneurysm surgery: A single-center retrospective review<...
TY - JOUR. T1 - Adenosine for temporary flow arrest during intracranial aneurysm surgery. T2 - A single-center retrospective review. AU - Bendok, Bernard R.. AU - Gupta, Dhanesh K.. AU - Rahme, Rudy J.. AU - Eddleman, Christopher S.. AU - Adel, Joseph G.. AU - Sherma, Arun K.. AU - Surdell, Daniel L.. AU - Bebawy, John F.. AU - Koht, Antoun. AU - Batjer, H. Hunt. PY - 2011/10/1. Y1 - 2011/10/1. N2 - Background: Clip application for temporary occlusion is not always practical or feasible. Adenosine is an alternative that provides brief periods of flow arrest that can be used to advantage in aneurysm surgery, but little has been published on its utility for this indication. Objective: To report our 2-year consecutive experience with 40 aneurysms in 40 patients for whom we used adenosine to achieve temporary arterial occlusion during aneurysm surgery. Methods: We retrospectively reviewed our clinical database between May 2007 and December 2009. All patients who underwent microsurgical clipping of ...
Stroke: Highlights of Selected Articles | StrokeStroke: Highlights of Selected Articles | Stroke
Patients with symptomatic intracranial aneurysms are frequently found to have additional aneurysms and may develop new aneurysms over time. LOTUS, long-term stability of coiled intracranial aneurysms, is a study in which MRA (3-D time of flight) was performed on patients in a large cohort with previously coiled aneurysms at 5 years follow-up. In 50 of 276 patients (18%), 75 additional aneurysms were found on follow-up MRA. The majority, 89%, of these additional aneurysms were unchanged, whereas only 5 had grown (from 1-3 mm) and only 2 were de novo (both 3 mm). The cumulative 5-year incidence of de novo aneurysm formation was 0.75%. The clinical implication of these findings from the MRA done at 5 years was that only 4 additional aneurysms in 3 patients were treated. The authors conclude that MRA screening of patients with coiled aneurysms within the first 5 years after treatment has a low rate of de novo aneurysm development and growth of additional aneurysms and an even lower rate of treatment ...
Influence of comorbidities on treatment of unruptured intracranial aneurysms in the elderly<...Influence of comorbidities on treatment of unruptured intracranial aneurysms in the elderly<...
TY - JOUR. T1 - Influence of comorbidities on treatment of unruptured intracranial aneurysms in the elderly. AU - ONeill, Anthea H.. AU - Chandra, Ronil V.. AU - Slater, Lee-Anne. AU - Chong, Winston. AU - Xenos, Christopher. AU - Danks, Andrew Robert. AU - Lai, Leon T.. PY - 2019/4/1. Y1 - 2019/4/1. N2 - Current evidence does not conclusively justify conservative management of unruptured intracranial aneurysms (UIA) in the elderly (age ≥ 65 years). To rationalise intervention, the authors investigated the role of age and comorbidity burden on treatment outcomes. A retrospective chart review for consecutive cases of UIAs treated in the elderly between 2007 and 2018 was performed. Preoperative Charlson Comorbidity Index (CCI) and Neurovascular Comorbidities Index (NCI) were calculated. Standard statistical methods with univariate and multiple logistic regression were used. A total of 123 patients (46 surgery, 77 endovascular) with 131 UIAs were treated. The mean age was 70.6 ± 4.1 years, and ...
Accuracy in Identifying the Source of Subarachnoid Hemorrhage in the Setting of Multiple Intracranial Aneurysms | CV SectionAccuracy in Identifying the Source of Subarachnoid Hemorrhage in the Setting of Multiple Intracranial Aneurysms | CV Section
In the setting of a patient with aneurysmal subarachnoid hemorrhage and multiple intracranial aneurysms the hemorrhage pattern is often the indicator ...
Unruptured intracranial aneurysmsUnruptured intracranial aneurysms
Between 3.6 and 6% of the population harbour an unruptured intracranial aneurysm. Risk of rupture is related to aneurysm site and size and whether or not the patient has already had a subarachnoid haemorrhage (SAH) from another aneurysm. In ISUIA 2, the rupture rate for anterior circulation aneurysm …
Management of anterior inferior cerebellar artery aneurysms: Endovascular treatment and clinical outcome<...Management of anterior inferior cerebellar artery aneurysms: Endovascular treatment and clinical outcome<...
TY - JOUR. T1 - Management of anterior inferior cerebellar artery aneurysms. T2 - Endovascular treatment and clinical outcome. AU - Suh, S. H.. AU - Kim, D. J.. AU - Kim, D. I.. AU - Kim, Byungmoon. AU - Chung, T. S.. AU - Hong, C. K.. AU - Jung, J. Y.. PY - 2011/1/1. Y1 - 2011/1/1. N2 - BACKGROUND AND PURPOSE: AICA aneurysms are rare and a challenge to treat surgically. We present our experience of the angiographic results and the clinical outcomes for 9 AICA aneurysms treated by EVT. MATERIALS AND METHODS: Between 1997 and 2009, EVT was attempted for 9 AICA aneurysms. Six patients presented with SAH, and 3 aneurysms were found incidentally. The location of the aneurysms was the proximal AICA in 7 and the distal AICA in 2. Five aneurysms originated from an AICA-PICA variant. Clinical outcomes and procedural complications were evaluated, and angiography was performed 6, 12, and 24 months after embolization to confirm recanalization of the coiled aneurysm. RESULTS: EVT was technically successful ...
De novo basilar tip aneurysm: Case report and literature reviewDe novo basilar tip aneurysm: Case report and literature review
SUZUKI, M.T.M. et al. De novo basilar tip aneurysm: Case report and literature review. Neurocirugía [online]. 2011, vol.22, n.3, pp.251-254. ISSN 1130-1473.. The de novo aneurysms are the formation of new aneurysms in a location previously observed to be normal by a cerebral angiography or direct microsurgical exploration. In this report, we present a review of the theme and describe a case of a ruptured de novo basilar tip aneurysm in a patient previously treated with carotid occlusion for a giant intracavernous aneurysm and microsurgical clipping of contralateral posterior communicating artery aneurysm.. Keywords : Basilar artery; De novo aneurysm; Subarachnoid hemorrhage. ...
Stent assisted coil embolization of wide-necked bilobed anterior inferior cerebellar artery aneurysm with incorporated artery...Stent assisted coil embolization of wide-necked bilobed anterior inferior cerebellar artery aneurysm with incorporated artery...
Clinical presentation A middle-aged patient was referred for treatment of a bilobed saccular aneurysm identified on a CT angiogram performed for a subarachnoid hemorrhage which occurred 20 days prior to presentation. A diagnostic angiogram showed a bilobed wide-necked saccular aneurysm at the AICA origin with the AICA arising from the dome of the aneurysm and also supplying the territory of the posterior inferior cerebellar artery. The therapeutic procedure involved trans-aneurysmal cannulation of the AICA with the microcatheter left in situ. Another microcatheter was maneuvered into the larger dome of the aneurysm. A stent was then deployed in the basilar artery, jailing the previous microcatheter in the aneurysm. Helical Guglielmi detachable coils were deployed in the aneurysm resulting in complete occlusion of the aneurysm with preservation of the AICA.. ...
Are Multiple Intracranial Aneurysms, More Than 5 At One Time, Almost Exclusively A Female Disease? A Clinical Series and...Are Multiple Intracranial Aneurysms, More Than 5 At One Time, Almost Exclusively A Female Disease? A Clinical Series and...
The clinical characteristics of elderly patients with multiple IAs were studied in 481 patients by Inagawa [31]. Patients were divided into two groups: group 1 - 59 years of age or younger and group 2- 60 years of age or older. Of the 481 patients, 136 (28%) had multiple aneurysms. The percentage of patients with multiple aneurysms was 30% for group 1 and 27% for group 2. The rate of multiple aneurysms was significantly less in males than in females (17% versus 31%). Due to the small sample size, no significant difference could be found between the male and female age groups in terms of the number of aneurysms by gender, yet it is important to highlight that there were no male patients reported in that series with 5 aneurysms or more. The only patients in this series reported to have 5 aneurysms or more were females; one patient in group 1 with 5 aneurysms and one with 6 aneurysms, and a single female patient with more than 5 aneurysms in group 2. Comparable findings were reported by Wilson et ...
Global Brain Aneurysm Treatment Market 2020 by manufacturers, Demand, application, and region 2024 - Divorce DivaGlobal Brain Aneurysm Treatment Market 2020 by manufacturers, Demand, application, and region 2024 - Divorce Diva
Brain Aneurysm Treatment Market Information: By Type (Surgery (Surgical Clipping, Endovascular Coiling), Medication (Antacid, Stool Softener)), Condition (Unruptured Aneurysm, Ruptured Aneurysm), End User (Hospitals, Clinics) - Global Forecast till 2023. Increasing Government Funding Projected to Accelerate the Global Brain Aneurysm Treatment Market. Brain aneurysm is an abnormal bulge in the blood vessels of the brain that can go on to cause severe health-based issues and possible even death. It causes the inner muscular layer of the blood vessel wall to weaken. After a prolonged period of time, the blood flow within the artery keeps pushing the thin wall portion and eventually ends-up rupturing it. The bleeding caused due to the ruptured brain artery is known as subarachnoid hemorrhage (SAH). The hemorrhage is so severe that it can lead to stroke, coma, or even death. Various factors contribute to its occurrence, including injury or trauma, cigarette smoking, blood infections, and others. ...
Advance Access: Impact of Young Age on the Presentation of Saccular Intracranial Aneurysms: Population-Based Analysis of 4082...Advance Access: Impact of Young Age on the Presentation of Saccular Intracranial Aneurysms: Population-Based Analysis of 4082...
Unruptured saccular intracranial aneurysm (sIA) is a relatively common disease (2%-3% prevalence).1 Asymptomatic unruptured sIAs are diagnosed increasingly frequently due to improved availability of magnetic resonance imaging (MRI) scans. Although sIAs may rupture causing devastating hemorrhage with mortality of 30% to 50%,2 most sIAs never rupture.3 The pathobiology of sIA formation and rupture need to be elucidated in…
Distal anterior inferior cerebellar artery aneurysms: Report of four cases<...Distal anterior inferior cerebellar artery aneurysms: Report of four cases<...
TY - JOUR. T1 - Distal anterior inferior cerebellar artery aneurysms. T2 - Report of four cases. AU - Zager, Eric L.. AU - Shaver, Ellen G.. AU - Hurst, Robert W.. AU - Flamm, Eugene S.. PY - 2002/9. Y1 - 2002/9. N2 - Aneurysms of the distal anterior inferior cerebellar artery (AICA) are rare; fewer than 100 cases have been reported. The authors detail their experience with four cases and present endovascular as well as microsurgical management options. The medical records and neuroimaging studies obtained in four patients who were treated at a single institution were reviewed. Clinical presentations, neuroimaging and intraoperative findings, and clinical outcomes were analyzed. There were three men and one woman; their mean age was 43 years. Two patients presented with acute subarachnoid hemorrhage (SAH), and two presented with ataxia and vertigo (one with tinnitus, the other with hearing loss). Angiographic studies demonstrated aneurysms of the distal segment of the AICA. In one patient with ...
Vikas Patel Explains Endovascular Stenting for Treatment of Brain AneurysmsVikas Patel Explains Endovascular Stenting for Treatment of Brain Aneurysms
A brain aneurysm is a uniquely devastating occurrence. An aneurysm happens when the artery walls in the brain thin and become unstable. They often form at branches or forks in the arteries where the structures are weaker. Without proper treatment, an aneurysm can lead to brain oxygen deprivation or death. When physicians want to treat a brain aneurysm, they have several different techniques at their disposal. One of the most effective methods is endovascular stenting. With an endovascular stent, doctors are able to create new pathways, avoiding the constriction of the blood going to the brain. Since a deficit of blood leading to the brain can cause such serious problems, doctors need to be aware of the consequences of their actions. Vikas Patel, an Interventional neuroradiologist from New Jersey, explains the procedure of the endovascular stent and how it can help a patient regain a full and healthy life. Brain Aneurysms A brain aneurysm is a ballooning or bulge in the brains blood vessels. It can
Hemodynamics in intracranial aneurysmsHemodynamics in intracranial aneurysms
Hemodynamics are considered a risk factor for the initiation, growth and rupture of intracranial aneurysms. In this thesis several aspects of the research of hemodynamics in intracranial aneurysms are discussed. First, I discuss the need to obtain aneurysm hemodynamics in a patient-specific manner, followed by possible clinical routines for obtaining such information. Second, the strengths and limitations of presented studies and the underlying technology are discussed. Third, the main outcome of the comparison study in chapter 10 is absence of additional value of aneurysm hemodynamics for characterization of ruptured versus unruptured aneurysm. This outcome raises questions whether there still is a future for hemodynamics in rupture risk prediction, and whether additional studies are still required to determine its definitive role for this purpose ...
Acutely ruptured intracranial saccular aneurysms treated with stent assisted coiling: complications and outcomes in 42...Acutely ruptured intracranial saccular aneurysms treated with stent assisted coiling: complications and outcomes in 42...
Background Antiplatelet agents are required to prevent thromboembolic complications from recently deployed intracranial stents, yet they carry a risk of bleeding complications that may be serious in patients with recent subarachnoid hemorrhage.. Method Consecutive patients at a single institution who had ruptured intracranial saccular aneurysms treated with stent assisted coiling were retrospectively reviewed. Our primary outcomes were ischemic stroke related to the stent and bleeding complications possibly related to antithrombotic therapy. Secondary outcomes included 3 month follow-up National Institute of Health Stroke Scale (NIHSS) scores and modified Rankin Scale (mRS) scores.. Results 44 aneurysms in 42 patients were treated. Seven patients experienced ischemic strokes during their hospitalization. Five ischemic strokes were secondary to vasospasm; one was definitely related to thrombus formation within the stent and one was possibly related to the stent. Two patients had asymptomatic ...
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SUMMARY: Giant intracranial aneurysms are rare vascular pathologies associated with high morbidity and mortality. The purpose of this in vivo study was to assess giant intracranial aneurysms and their wall microstructure by 7T MR imaging, previously only visualized in histopathologic examinations. Seven giant intracranial aneurysms were evaluated, and 2 aneurysms were available for histopathologic examination. Six of 7 (85.7%) showed intraluminal thrombus of various sizes. Aneurysm walls were depicted as hypointense in TOF-MRA and SWI sequences with excellent contrast ratios to adjacent brain parenchyma (range, 0.01-0.60 and 0.58-0.96, respectively). The triple-layered microstructure of the aneurysm walls was visualized in all aneurysms in TOF-MRA and SWI. This could be related to iron deposition in the wall, similar to the findings in 2 available histopathologic specimens. In vivo 7T TOF-MRA and SWI can delineate the aneurysm wall and the triple-layered wall microstructure in giant intracranial ...
Computed tomographic demonstration of the effect of proximal parent artery ligation for giant intracranial aneurysms.Computed tomographic demonstration of the effect of proximal parent artery ligation for giant intracranial aneurysms.
Four patients with giant intracranial aneurysms, which measured over 2.5 cm in diameter, were treated by ligation of the proximal parent artery. The location of the aneurysms were intracavernous in two patients, paraophthalmic in one patient, and ver
Endovascular treatment of very small intracranial aneurysms. - Nuffield Department of Surgical SciencesEndovascular treatment of very small intracranial aneurysms. - Nuffield Department of Surgical Sciences
OBJECT: Endovascular treatment of very small aneurysms poses a significant technical challenge for endovascular therapists. The authors review their experience with a series of patients who had intracranial aneurysms smaller than 3 mm in diameter. METHODS: Between 1995 and 2006, 97 very small aneurysms (defined for purposes of this study as | 3 mm in diameter) were diagnosed in 94 patients who were subsequently referred for endovascular treatment. All patients presented after subarachnoid hemorrhage, which was attributed to the very small aneurysms in 85 patients. The authors reviewed the endovascular treatment, the clinical and angiographic results of the embolization, and the complications. RESULTS: Five (5.2%) of the 97 endovascular procedures failed, and these patients underwent craniotomy and clip ligation. Of the 92 aneurysms successfully treated by coil embolization, 64 (69.6%) were completely occluded and 28 (30.4%) showed minor residual filling or neck remnants on the immediate postembolization
Research results show new technique for treating brain aneurysms is superior to surgery - University News Service - The...Research results show new technique for treating brain aneurysms is superior to surgery - University News Service - The...
Results of a study in the Oct. 26 issue of The Lancet show that researchers -- including a member of a University of Iowa Health Care team -- have determined that a new approach to treating ruptured aneurysms in the brain is superior to surgery.. Researchers at 44 medical centers in Australia, Europe and North America participated in the International Subarachnoid Aneurysm Trial (ISAT). The studys investigators ended the trial early because the early results definitively showed that the new technique achieved better outcomes for patients than traditional surgery.. A brain aneurysm is an abnormal bulging outward of the wall of an artery. The defect is most common among people between ages 35 and 60. Brain aneurysms can cause a stroke when they rupture and blood flows into the brain or the space closely surrounding the brain. The traditional treatment for a ruptured brain aneurysm was surgery. Neurosurgeons placed metal clips across the neck of the aneurysm in an effort to stop arterial blood ...
Endovascular coiling versus neurosurgical clipping in patients with unruptured intracranial aneurysm: a systematic review |...Endovascular coiling versus neurosurgical clipping in patients with unruptured intracranial aneurysm: a systematic review |...
Background To compare the effects of endovascular coiling and neurosurgical clipping in patients with unruptured intracranial aneurysm.
Segmentation of the thrombus of giant intracranial aneurysms from CT angiography scans with lattice Boltzmann method.Segmentation of the thrombus of giant intracranial aneurysms from CT angiography scans with lattice Boltzmann method.
Computed Tomography Angiography (CTA) plays an essential role in the diagnosis, treatment evaluation, and monitoring of cerebral aneurysms. Segmentation of CTA medical images of giant intracranial aneurysms (GIA) provides quantitative measurements of
Hemodynamics in Ruptured Intracranial Aneurysms | IntechOpenHemodynamics in Ruptured Intracranial Aneurysms | IntechOpen
Incidental detection of unruptured intracranial aneurysms (UIA) has increased in the recent years. There is a need in the clinical community to identify those that are prone to rupture and would require preventive treatment. Hemodynamics in cerebral blood vessels plays a key role in the lifetime cycle of intracranial aneurysms (IA). Understanding their initiation, growth, and rupture or stabilization may identify those hemodynamic features that lead to aneurysm instability and rupture. Modeling hemodynamics using computational fluid dynamics (CFD) could aid in understanding the processes in the development of IA. The neurosurgical approach during operation of IA allows direct visualization of the aneurysm sac and its sampling in many cases. Detailed analysis of the quality of the aneurysm wall under the microscope, together with histological assessment of the aneurysm wall and CFD modeling, can help in building complex knowledge on the relationship between the biology of the wall and hemodynamics.
Brain aneurysm: Signs, Indications, Symptoms, Causes, Treatment, Therapy, PreventionBrain aneurysm: Signs, Indications, Symptoms, Causes, Treatment, Therapy, Prevention
An estimated 6 million people in the United States have an unruptured aneurysm. A ruptured aneurysm will cause bleeding into the brain or the space closely surrounding the brain. A ruptured brain aneurysm can result in a subarachnoid hemorrhage (SAH), which can lead to a hemorrhagic stroke, brain damage and death. The most common type of aneurysm that accounts for about 90% of all IA is called a saccular cerebral aneurysm. It is also the most common cause of non-traumatic subarachnoid hemorrhage. This type of aneurysm is often known as a "berry" aneurysm due to its shape forming at the "Y" segment of arteries known as the arterial bifurcation. Another type of aneurysm is the fusiform aneurysm which rarely ruptures and appears inflamed on all sides of the blood vessel. ...
Accuracy of 320-detector row nonsubtracted and subtracted volume CT angiography in evaluating small cerebral aneurysmsAccuracy of 320-detector row nonsubtracted and subtracted volume CT angiography in evaluating small cerebral aneurysms
J Neurosurg 127:725-731, 2017. The study aimed to assess the diagnostic accuracy of 320-detector row nonsubtracted and subtracted volume CT angiography (VCTA) in detecting small cerebral aneurysms (, 3 mm) compared with 3D digital subtraction angiography (3D DSA).. METHODS Six hundred sixty-two patients underwent 320-detector row VCTA and 3D DSA for suspected cerebral aneurysms. Five neuroradiologists independently reviewed VCTA and 3D DSA images. The 3D DSA was considered the reference standard, and the sensitivity, specificity, and accuracy of nonsubtracted and subtracted VCTA in depicting small aneurysms were analyzed. A p value , 0.05 was considered a significant difference.. RESULTS According to 3D DSA images, 98 small cerebral aneurysms were identified in 90 of 662 patients. Nonsubtracted VCTA depicted 90 small aneurysms. Ten small aneurysms were missed, and 2 small aneurysms were misdiagnosed. The missed small aneurysms were located almost in the internal carotid artery, near bone tissue. ...
Brain Aneurysm & Stroke Program | Altair HealthBrain Aneurysm & Stroke Program | Altair Health
The Brain Aneurysm & Stroke Program, part of the ANS nerovascular Center, offers a multidisciplinary and highly advanced approach to the diagnosis and treatment of brain aneurysms and other related conditions. Under the directorship of Dr. Ronald Benitez, the Brain Aneurysm & Stroke Program maintains high-level collaboration with the top comprehensive stroke centers in the state of New Jersey. Our program provides the latest equipment and technology to treat a variety of disorders in state-of-the-art facilities. Among the conditions we treat are brain aneurysms, cerebral hemorrhage, arteriovenous malformations (AVMs), cavernous angiomas, and ischemic stroke. ...
Maine Brain Aneurysm Awareness EventMaine Brain Aneurysm Awareness Event
If youre in the Northern New England area or Maine, the KAT-Walk and Karo-5K Run for Brain Aneurysm Awareness will be held on Saturday, September 12, 2015 in Portland Maine Lace up your walking and running shoes and join us for the KAT-Walk & Karo-5K for Brain Aneurysm Awareness. This annual event will benefit the Maine Brain Aneurysm Awareness Committee in our local effort to provide brain aneurysm awareness, education, funding of research, and general support centered on the Brain
Maine Brain Aneurysm Awareness EventMaine Brain Aneurysm Awareness Event
If youre in the Northern New England area or Maine, the KAT-Walk and Karo-5K Run for Brain Aneurysm Awareness will be held on Saturday, September 12, 2015 in Portland Maine Lace up your walking and running shoes and join us for the KAT-Walk & Karo-5K for Brain Aneurysm Awareness. This annual event will benefit the Maine Brain Aneurysm Awareness Committee in our local effort to provide brain aneurysm awareness, education, funding of research, and general support centered on the Brain
Cerebral Aneurysm | AdventHealth Neuroscience InstituteCerebral Aneurysm | AdventHealth Neuroscience Institute
Cerebral aneurysms are bulging, weakened areas in the wall of a brain artery that create abnormal widening, ballooning or a fluid-filled internal blister. Also called brain aneurysms or intracranial aneurysms, they can result from an injury, or they can occur spontaneously. Arteries in any part of the brain can develop an aneurysm, but they are usually located in the front of the brain, which supports the rest of the brain tissue with oxygen-rich blood. The majority of brain aneurysms are small - less than four-tenths of an inch in diameter - and occur without any symptoms. These smaller aneurysms may not rupture (tear), but as the size of an aneurysm increases, so does the risk of rupture or developing another aneurysm.. The wall of an aneurysm is thin and weak, meaning it could rupture. When a blood vessel ruptures and bleeds into the brain, a stroke occurs and there is a significant risk to a persons life. The cells and tissue in the brain do not get the oxygen and nutrients needed, pressure ...
Detection of intracranial aneurysms with unenhanced and echo contrast enhanced transcranial power Doppler | Journal of...Detection of intracranial aneurysms with unenhanced and echo contrast enhanced transcranial power Doppler | Journal of...
This study has shown that the detection of intracranial aneurysms by transcranial power Doppler is highly dependent on the size of the aneurysm, with anatomical position and morphology also determining factors. Ultrasonic contrast agent significantly increased the detection rate.. The detection rates in this study are not comparable with some previous studies. However, most published papers on aneurysm detection rates have been performed with either knowledge of the results of other imaging investigations (CT or MRI) or had chosen a selected population of subarachnoid haemorrhage (only aneurysm positive patients with subarachnoid haemorrhage were included). Becker et al 14 detected 76% of aneurysms, which was higher than that detected by angiography (73%). The detection rate of Klotzsch et al 21 was, however, comparable with our study (47%) despite the prior knowledge of the presence of an aneurysm.. Despite the superficial location of middle cerebral artery aneurysms, a relatively low number ...
Risk factors for hemorrhagic complications following pipeline embolization device treatment of intracranial aneurysms: Results...Risk factors for hemorrhagic complications following pipeline embolization device treatment of intracranial aneurysms: Results...
TY - JOUR. T1 - Risk factors for hemorrhagic complications following pipeline embolization device treatment of intracranial aneurysms. T2 - Results from the international retrospective study of the pipeline embolization device. AU - Brinjikji, W.. AU - Lanzino, G.. AU - Cloft, H. J.. AU - Siddiqui, A. H.. AU - Kallmes, D. F.. PY - 2015/12. Y1 - 2015/12. N2 - BACKGROUND AND PURPOSE: Spontaneous intraparenchymal hemorrhage is a dreaded complication of unknown etiology following flow-diversion treatment. Using the International Retrospective Study of the Pipeline Embolization Device registry, we studied demographic, aneurysm, and procedural characteristics associated with intraparenchymal hemorrhage following Pipeline Embolization Device treatment. MATERIALS AND METHODS: Weidentified patients in the International Retrospective Study of the Pipeline Embolization Device registry with intraparenchymal hemorrhage unrelated to index aneurysm rupture post-Pipeline Embolization Device treatment. The rate ...
Pipeline embolization device receives FDA Premarket Approval - Interventional NewsPipeline embolization device receives FDA Premarket Approval - Interventional News
The Pipeline embolization device is a breakthrough and life-saving endovascular treatment for large or giant wide-neck brain aneurysms," said Joe Woody, president, Vascular Therapies, Covidien. "Pipeline now offers hope for those patients who have had no other options for treating this often debilitating and even fatal medical condition.". The Pipeline embolization device PMA application was based on the results of the PUFS (Pipeline for uncoilable or failed aneurysms) clinical trial, a single-arm study of large and giant, wide-neck or fusiform aneurysms that included safety and efficacy data on 108 patients.. "Brain aneurysms are a silent killer because most show no symptoms over time," said Christine Buckley, executive Director, The Brain Aneurysm Foundation. "The Pipeline embolization device now provides patients with a safe and effective treatment of large or giant, wide-neck aneurysms, which remained an unmet clinical need until now.". The Pipeline embolization device has received CE mark ...
Baptist Medical Center Jacksonville provides new treatment for ruptured and unruptured brain aneurysms - The Westside...Baptist Medical Center Jacksonville provides new treatment for ruptured and unruptured brain aneurysms - The Westside...
Baptist Medical Center Jacksonville provides new treatment for ruptured and unruptured brain aneurysms. By Cindy Hamilton. Baptist Medical Center Jacksonville is part of an international trial evaluating a new treatment for both ruptured and unruptured brain aneurysms.. The worldwide study, WEB Intrasaccular Therapy Study (WEB-IT), is approved to enroll 139 patients at up to 25 sites in the U.S., Canada, and Europe and will evaluate the WEB for the treatment of brain aneurysms. Baptist Medical Center Jacksonville had the first cases in the state today performed by Ricardo Hanel, MD, Phd, and neurovascular surgeon with Lyerly Neurosurgery. Baptist Medical Center Jacksonville is the second site in the U.S. where the procedure has been conducted. Visiting physicians also observed.. The WEB Aneurysm Embolization System consists of a dense mesh constructed from a large number of extremely fine wires that is placed into an aneurysm through a catheter by way of the femoral artery. The WEB reduces and ...
HydroCoil embolic system showed superior outcomes compared to bare platinum coils in the treatment of cerebral aneurysms -...HydroCoil embolic system showed superior outcomes compared to bare platinum coils in the treatment of cerebral aneurysms -...
We are very pleased with the exceptional results from this landmark trial. It continues to validate findings from previous multicentre and single-centre trials, which is that the HydroCoil system provides excellent results in reducing aneurysm recurrence and retreatment in a wide range of cerebral aneurysms as compared to bare platinum coils," said Richard Cappetta, president and CEO, MicroVention-Terumo.. Procedural safety and efficacy results for HELPS, previously published in 2008, found that the. HydroCoil system can be safely used in a wide spectrum of aneurysms with a risk profile equivalent to thatof bare platinum coils.. Since the HELPS patient enrolment was completed in February 2007, MicroVention-Terumo has continued to innovate the HydroCoil line of coils, including the HydroSoft finishing coil for filling small spaces that provides hydrogel at the neck of the aneurysm, and the HydroFrame framing coil that provides optimal framing of the aneurysm with the clinical benefits of ...
External Validation of the ELAPSS Score for Prediction of Unruptured Intracranial Aneurysm Growth Risk<...External Validation of the ELAPSS Score for Prediction of Unruptured Intracranial Aneurysm Growth Risk<...
TY - JOUR. T1 - External Validation of the ELAPSS Score for Prediction of Unruptured Intracranial Aneurysm Growth Risk. AU - Kammen, Mayte Sánchez van. AU - Greving, Jacoba P. AU - Kuroda, Satoshi. AU - Kashiwazaki, Daina. AU - Morita, Akio. AU - Shiokawa, Yoshiaki. AU - Kimura, Toshikazu. AU - Cognard, Christophe. AU - Januel, Anne C. AU - Lindgren, Antti. AU - Koivisto, Timo. AU - Jääskeläinen, Juha E. AU - Ronkainen, Antti. AU - Pyysalo, Liisa. AU - Öhman, Juha. AU - Rahi, Melissa. AU - Kuhmonen, Johanna. AU - Rinne, Jaakko. AU - Leemans, Eva L. AU - Majoie, Charles B. AU - Vandertop, W Peter. AU - Verbaan, Dagmar. AU - Roos, Yvo B W E M. AU - Berg, René van den. AU - Boogaarts, Hieronymus D. AU - Moudrous, Walid. AU - Wijngaard, Ido R van den. AU - Hove, Laura Ten. AU - Teo, Mario. AU - George, Edward J St. AU - Hackenberg, Katharina A M. AU - Abdulazim, Amr. AU - Etminan, Nima. AU - Rinkel, Gabriël J E. AU - Vergouwen, Mervyn D I. PY - 2019/9/1. Y1 - 2019/9/1. N2 - Background and ...
Nurse recognized for outstanding work with brain aneurysm patients - Massachusetts General Hospital, Boston, MANurse recognized for outstanding work with brain aneurysm patients - Massachusetts General Hospital, Boston, MA
For 27 years Deidre Buckley, RN, NP, of the Massachusetts General Hospital Fireman Vascular Centers Brain Aneurysm and Arteriovenous Malformations Program has made it her life mission to help patients like the 34-year-old mother of four who was diagnosed with a brain aneurysm in April.. "By the end of the visit, she realized she was going to get through," says Buckley.. For this reason, the Boston Globe recently recognized Buckleys outstanding work in its honorary feature Salute to Nurses. Selected from nurses nominated from across New England, including 23 from Mass General, Buckley stands out as continually going above and beyond the call of duty.. "Its something so unique, that you are able to give to others on a daily basis, sometimes without even knowing it," says Buckley.. Using education as a clinical tool In recent years, tremendous progress has been made in treating brain aneurysms. Both neurosurgical and minimally invasive endovascular procedures, such as coiling and stenting, ...
Covidien Pipeline Embolization Device (August, 2012)Covidien Pipeline Embolization Device (August, 2012)
Theres a new way to treat life-threatening giant aneurysms of the internal carotid artery: Covidiens Pipeline Embolization Device. The flexible 75% coba
Treatment of giant fusiform aneurysms of the basilar trunk with intra-aneurysmal and basilar artery coil embolization<...Treatment of giant fusiform aneurysms of the basilar trunk with intra-aneurysmal and basilar artery coil embolization<...
TY - JOUR. T1 - Treatment of giant fusiform aneurysms of the basilar trunk with intra-aneurysmal and basilar artery coil embolization. AU - Hassan, Tamer. AU - Ezura, Masayuki. AU - Takahashi, Akira. AU - Debrun, Gerard. AU - Gobin, Y. Pierre. PY - 2004/11. Y1 - 2004/11. N2 - Objective The authors report their experience in endovascular treatment of basilar artery (BA) trunk aneurysms by intra-aneurysmal and BA occlusion. Methods Four patients were referred to our hospital from 1995 until 2002 with variable clinical presentations and radiologic appearances. All the patients were subjected for tolerability to balloon BA occlusion test to verify the collateral supply from the posterior communicating arteries. The patients were treated by intra-aneurysmal embolization together with basilar artery occlusion. Results All the aneurysms were successfully isolated from the circulation. Transient postoperative neurologic deficits were constant findings in all the cases. Outcome was finally good for all ...
Investigating Cellular Therapeutics for Aneurysm | Regenerative Medicine MinnesotaInvestigating Cellular Therapeutics for Aneurysm | Regenerative Medicine Minnesota
Biobusiness grant recipient: Dr. Brenda Ogle, PhD. Grant Period: 2015-2016. Site: Department of Biomedical Engineering , University of Minnesota. Click here to read Ogles Final Report. About six million people in the United States have an unruptured brain aneurysm, according to the Brain Aneurysm Foundation, which means that one in every 50 Americans have a bulging, weak area in the wall of an artery that brings oxygen-rich blood to the brain. The weak areas of the arteries may rupture and hemorrhage, spilling blood instead of delivering it to cells throughout the body. A ruptured artery in the brain causes a stroke. Also, 85 percent of aneurysms go undiagnosed until after they rupture, and one-third of patients with ruptured aneurysm die before they even get to the hospital. Therefore, it is essential to treat aneurysms before they rupture.. Doctors currently treat unruptured intracranial aneurysms (UIA) by blocking the aneurysm to prevent blood from entering the weak ballooned portion of the ...
cerebral aneurysm - Matthew Lawson, M.D.cerebral aneurysm - Matthew Lawson, M.D.
Patients who present with subarachnoid hemorrhage who have not had a traumatic injury have spontaneous subarachnoid hemorrhage. This is commonly due to an abnormality of the blood vessels within the subarachnoid space that has caused them to rupture and bleed on their own. The most common vascular abnormality leading to subarachnoid hemorrhage is a cerebral aneurysm, or brain aneurysm, but other vascular conditions can also cause subarachnoid hemorrhage. When a patient comes to the hospital with subarachnoid hemorrhage, studies such as CT Angiography or Cerebral Angiography are performed to look for a brain aneurysm or malformation that may have caused the bleeding.. Aneurysmal Subarachnoid Hemorrhage is a medical emergency. It strikes roughly roughly 30,000 people annually in the United States. Many of these people are critically ill. Up to 40% of patients with subarachnoid hemorrhage from a ruptured aneurysm die, and many pass away quickly. Symptoms of SAH include sudden onset severe headache ...
Modifying Flow in the ICA Bifurcation: Pipeline Deployment from the Su by E. Nossek, D. J. Chalif et al."Modifying Flow in the ICA Bifurcation: Pipeline Deployment from the Su" by E. Nossek, D. J. Chalif et al.
BACKGROUND AND PURPOSE: Utility of the Pipeline Embolization Device extending to the M1 and its clinical and flow consequences at the ICA bifurcation have not been characterized. We analyzed flow modification in cases where a single Pipeline Embolization Device was deployed from the M1 to the distal supraclinoid ICA, covering the A1, for aneurysm treatment. MATERIALS AND METHODS: A1 flow modifications and size regression in postprocedure and follow-up angiography were analyzed. Vessel diameters and ratios of the proximal A1 and M1 segments and the distal ICA were assessed. Relationships between Pipeline Embolization Device nominal diameter and the vessel diameters at landing zones were obtained. Clinical assessments after flow modification were documented. RESULTS: Six of 7 patients demonstrated no change of flow in the anterior cerebral artery/anterior communicating artery complex at immediate postembolization angiography. All patients who underwent follow-up angiography demonstrated size regression of
Saccular aneurysm | definition of saccular aneurysm by Medical dictionarySaccular aneurysm | definition of saccular aneurysm by Medical dictionary
Looking for online definition of saccular aneurysm in the Medical Dictionary? saccular aneurysm explanation free. What is saccular aneurysm? Meaning of saccular aneurysm medical term. What does saccular aneurysm mean?
Treatment failure of fetal posterior communicating artery aneurysms wi by Peter Kan, Edward Duckworth et al."Treatment failure of fetal posterior communicating artery aneurysms wi" by Peter Kan, Edward Duckworth et al.
Aneurysms that involve the internal carotid artery and posterior communicating artery junction and incorporate a fetal posterior cerebral artery are known as fetal posterior communicating artery aneurysms. We report the outcomes of four patients with fetal posterior communicating artery aneurysms who underwent treatment with the pipeline embolization device with or without adjunctive coil embolization. In our study, all four patients failed to achieve aneurysm occlusion at the last follow-up evaluation. Based on our results, we currently do not recommend the use of the flow diverter for the treatment of fetal posterior communicating artery aneurysms.
The risk of intravenous thrombolysis-induced intracranial hemorrhage in Taiwanese patients with unruptured intracranial...The risk of intravenous thrombolysis-induced intracranial hemorrhage in Taiwanese patients with unruptured intracranial...
TY - JOUR. T1 - The risk of intravenous thrombolysis-induced intracranial hemorrhage in Taiwanese patients with unruptured intracranial aneurysm. AU - Chiu, Wei Ting. AU - Hong, Chien Tai. AU - Chi, Nai Fang. AU - Hu, Chaur Jong. AU - Hu, Han Hwa. AU - Chan, Lung. PY - 2017/6/1. Y1 - 2017/6/1. N2 - Background The presence of an intracranial aneurysm is contraindicated to recombinant tissue plasminogen activator (r-tPA) treatment for acute ischemic stroke. However, it is difficult to exclude asymptomatic intracranial aneurysms by using conventional, noncontrast head computed tomography (CT), which is the only neuroimaging suggested before r-tPA. Recent case reports and series have shown that administering r-tPA to patients with a pre-existing aneurysm does not increase the bleeding risk. However, Asians are known to have a relatively higher bleeding risk, and little evidence is available regarding the risk of using r-tPA on Asian patients with intracranial aneurysms. Methods Medical records from ...
Microsurgical Clipping for Brain Aneurysms | Johns Hopkins MedicineMicrosurgical Clipping for Brain Aneurysms | Johns Hopkins Medicine
Microsurgical clipping is a technique that cuts off the blood supply to a brain aneurysm to prevent it from rupturing or to control bleeding if a rupture has already occurred.
Missed Anterior Inferior Cerebellar Artery Aneurysm Mimicking Vestibular Neuritis-Clues to Prevent Misdiagnosis - Zurich Open...Missed Anterior Inferior Cerebellar Artery Aneurysm Mimicking Vestibular Neuritis-Clues to Prevent Misdiagnosis - Zurich Open...
We discuss a case with combined vestibulocochlear and facial neuropathy mimicking a less urgent peripheral vestibular pattern of acute vestibular syndrome (AVS). With initial magnetic resonance imaging read as normal, the patient was treated for vestibular neuropathy until headaches worsened and a diagnosis of subarachnoid hemorrhage was made. On conventional angiography, a ruptured distal right-sided aneurysm of the anterior inferior cerebellar artery was diagnosed and coiled. Whereas acute vestibular loss usually points to a benign peripheral cause of AVS, combined neuropathy of the vestibulocochlear and the facial nerve requires immediate neuroimaging focusing on the cerebellopontine angle. Imaging should be assessed jointly by neuroradiologists and the clinicians in charge to take the clinical context into account. ...
Comparative computational study of thrombosis in cerebral and abdominal aortic Aneurysms - STIAS: The Stellenbosch Institute...Comparative computational study of thrombosis in cerebral and abdominal aortic Aneurysms - STIAS: The Stellenbosch Institute...
Thrombosis is closely linked to aneurysm evolution. In some cases, the presence of a clot can accelerate the time to aneurysm rupture while in others, it can stabilise the aneurysm and prevent rupture. The few computational models that simulate aneurysm thrombosis have focused on either cerebral aneurysms or on abdominal aortic aneurysms. The aim of these models has been to predict thrombosis outcome following intervention, or to better understand the processes at play during aneurysm thrombus formation. In this work, a joint thrombosis model which can be applied in both cerebral aneurysms and abdominal aortic aneurysms is proposed. It is thought that such an approach will be useful for elucidating clotting features which are common to both pathologies, and highlighting the key differences. This information will be useful for disease management and therapeutic approach. In my previous work, I have developed a computational model of thrombosis in cerebral aneurysms. In this work, I would like to ...
In vitro evaluation of flow divertors in an elastase-induced saccular aneurysm model in rabbitIn vitro evaluation of flow divertors in an elastase-induced saccular aneurysm model in rabbit
Endovascular coiling is an acceptable treatment of intracranial aneurysms, yet long term follow-ups suggest that endovascular coiling fails to achieve complete aneurysm occlusions particularly in wide-neck and giant aneurysms. Placing of a stentlike device across the aneurysm neck may be sufficient …
Medical record and imaging evaluation to identify arterial tortuosity phenotype in populations at risk for intracranial...Medical record and imaging evaluation to identify arterial tortuosity phenotype in populations at risk for intracranial...
TY - JOUR. T1 - Medical record and imaging evaluation to identify arterial tortuosity phenotype in populations at risk for intracranial aneurysms.. AU - Diedrich, Karl T.. AU - Roberts, John A.. AU - Schmidt, Richard H.. AU - Albright, Lisa A.Cannon. AU - Yetman, Anji T.. AU - Parker, Dennis L.. PY - 2011. Y1 - 2011. N2 - High arterial tortuosity may signify early arterial pathology which may precede development of intracranial aneurysms. We measured arterial tortuosity of intracranial vessels and reviewed the medical records of three groups of patients: with intracranial aneurysms, without aneurysms but at increased clinical risk, and controls without aneurysms or associated risk factors. There was significant but inconsistent evidence of increased arterial tortuosity in aneurysm cases and high-risk cases across different arteries. Medical records review identified that a subset of aneurysm cases carried a diagnosis of Loeys-Dietz syndrome that is often misdiagnosed as Marfan syndrome. We found ...
Thoracic aortic aneurysm - Cancer Therapy AdvisorThoracic aortic aneurysm - Cancer Therapy Advisor
Thoracic aortic aneurysms occur in 3 to 4% of persons older than 65 years. The incidence of thoracic aneurysm is approximately 6 to 10 cases per 100,000 person years with the incidence of thoracic aneurysm rupture occurring in 3.5 per 100,000 persons. The average age of diagnosis is 69 years. The prevalence of thoracic aortic aneurysm is up to 4.2% of the general population without hypertension. Most thoracic aortic aneurysms occur in the ascending aorta or the aortic arch. Aneurysm rupture accounts for 60% of deaths. Degenerative aneurysm associated with advanced age most commonly seen. There is no difference between the incidence in males versus females. Arteriosclerosis is the most common cause of thoracic aneurysm involving the descending aorta and aortic arch. It is most common in older individuals with males affected more than females. The etiology of thoracic aortic aneurysm is dependent on the location of the aneurysm. Ascending thoracic aorta aneurysm can be caused by cystic medial ...
a2 anterior cerebral artery aneurysm [Operative Neurosurgery]a2 anterior cerebral artery aneurysm [Operative Neurosurgery]
A2 anterior cerebral artery aneurysm Also named Proximal pericallosal artery aneurysm. The A2 aneurysms are located between the anterior communicating artery complex and the genu of the corpus callosum on the frontobasal branches. Epidemiology They are very rare with an incidence of 0.2-1% of all intracranial aneurysms . In the
Advanced digital subtraction angiography and MR fusion imaging protocol applied to accurate placement of flow diverter device<...Advanced digital subtraction angiography and MR fusion imaging protocol applied to accurate placement of flow diverter device<...
TY - JOUR. T1 - Advanced digital subtraction angiography and MR fusion imaging protocol applied to accurate placement of flow diverter device. AU - Faragò, Giuseppe. AU - Caldiera, Valentina. AU - Tempra, Giovanni. AU - Ciceri, Elisa. PY - 2016/2/1. Y1 - 2016/2/1. N2 - In recent years there has been a progressive increase in interventional neuroradiology procedures, partially due to improvements in devices, but also to the simultaneous development of technologies and radiological images. Cone beam CT (Dyna-CT; Siemens) is a method recently used to obtain pseudo CT images from digital subtraction angiography (DSA) with a flat panel detector. Using dedicated software, it is then possible to merge Dyna-CT images with images from a different source. We report here the usefulness of advanced DSA techniques (Syngo- Dyna CT, three-dimensional DSA iPilot) for the treatment of an intracranial aneurysm with a flow diverter device. Merging MR and Dyna-CT images at the end of the procedure proved to be a ...
Ultra-high-resolution subtraction CT angiography in the follow-up of treated intracranial aneurysms | Insights into Imaging |...Ultra-high-resolution subtraction CT angiography in the follow-up of treated intracranial aneurysms | Insights into Imaging |...
In subtraction CT angiography (CTA), a non-contrast CT acquisition is subtracted from a contrast-enhanced CTA acquisition. Subtraction CTA can be applied in the detection, classification, and follow-up of intracranial aneurysms and is advantageous over conventional angiography because of its non-invasive nature, shorter examination time, and lower costs. Recently, an ultra-high-resolution CT scanner has been introduced in clinical practice offering an in-plane spatial resolution of up to 0.234 mm, approaching the resolution as seen during conventional invasive digital subtraction angiography (DSA). The twofold increase in spatial resolution as compared to a conventional CT scanner could improve the evaluation of small vascular structures and, coupled with dedicated post-processing techniques, further reduce metal artifacts. Technical considerations using a state-of-the-art high-resolution subtraction CTA protocol are discussed for application in the follow-up of surgical and endovascular treated
Search Results | jnsSearch Results | jns
Object. If clip application or coil placement for treatment of intracranial aneurysms is not feasible, the parent vessel can be occluded to induce thrombosis of the aneurysm. The Excimer laser-assisted anastomosis technique allows the construction of a high-flow bypass in patients who cannot tolerate such an occlusion. The authors assessed the complications of this procedure and clinical outcomes after the construction of high-flow bypasses in patients with intracranial aneurysms.. Methods. Data were retrospectively collected on patient and aneurysm characteristics, procedural complications, and functional outcomes in 77 patients in whom a high-flow bypass was constructed. Logistic regression analysis was used to quantify the relationships between patient and aneurysm characteristics on the one hand and outcome measures on the other.. Fifty-one patients harbored a giant aneurysm, 24 patients suffered from a ruptured aneurysm, and 35 patients from an unruptured symptomatic aneurysm. In 22 ...
Peripheral signal void ring in giant vertebral aneurysm: MR and pathology findings<...Peripheral signal void ring in giant vertebral aneurysm: MR and pathology findings<...
TY - JOUR. T1 - Peripheral signal void ring in giant vertebral aneurysm. T2 - MR and pathology findings. AU - Hahn, F. J.. AU - Ong, E.. AU - McComb, Rodney D. AU - Leibrock, L.. PY - 1986/1/1. Y1 - 1986/1/1. N2 - Thin, signal void rims have been noted to surround intracerebral hemorrhages and ruptured intracranial aneurysms on magnetic resonance imaging. Proposed mechanisms include hemosiderin deposition in macrophages and high blood flow. The authors describe an example of a thick, signal void ring in a peripheral luminal thrombus of a giant vertebral aneurysm.. AB - Thin, signal void rims have been noted to surround intracerebral hemorrhages and ruptured intracranial aneurysms on magnetic resonance imaging. Proposed mechanisms include hemosiderin deposition in macrophages and high blood flow. The authors describe an example of a thick, signal void ring in a peripheral luminal thrombus of a giant vertebral aneurysm.. KW - Aneurysm, intracranial. KW - Hematoma, cerebral. KW - Magnetic resonance ...
NewYork-Presbyterian Queens - Thoracic Aortic AneurysmNewYork-Presbyterian Queens - Thoracic Aortic Aneurysm
The shape of an aneurysm is described as being fusiform or saccular which helps to identify a true aneurysm. A true aneurysm involves all three layers of the arterial blood vessel wall. The more common fusiform-shaped aneurysm bulges or balloons out on all sides of the aorta. A saccular-shaped aneurysm bulges or balloons out only on one side.. The aorta is under constant pressure from blood being ejected from the heart. With each heartbeat, the walls of the aorta expand and spring back, exerting continual pressure or stress on the already weakened aneurysm wall. Therefore, there is a potential for rupture (bursting) or dissection (separation of the layers of the thoracic aortic wall), which may cause life-threatening hemorrhage (uncontrolled bleeding) and, potentially, death.. Once formed, an aneurysm will gradually increase in size and there will be a progressive weakening of the aneurysm wall. Treatment for a thoracic aneurysm may include surgical repair or removal of the aneurysm to prevent ...
Archives of Neuroscience | Neuronavigation for Intraoperative Localization of Cerebral AneurysmsArchives of Neuroscience | Neuronavigation for Intraoperative Localization of Cerebral Aneurysms
It is important to localize brain lesions and prevent damage to vital structures during operation of brain pathologies. Many techniques have been developed but a more accurate localizing technique is still needed. Neuronavigation is used for this proposes and its utilities are in: biopsy and resection of tumors, endoscopy, skull base surgery and functional neurosurgery. Reports of its use in aneurysmal surgery are scarce.. Schmid-Elsaesser et al. stated that Navigation-CT angiography is useful when performing surgery on unruptured aneurysms, especially middle cerebral artery (MCA) aneurysms. They reported that the deviation of the neck in navigation-CT angiography was less than 2.6 mm and that, with this instrument, MCA aneurysms were approached via minicraniotomy, avoiding detachment of the temporalis muscle. Also they stated that current navigation systems are not precise enough to allow "blind" aneurysm clipping by placing a real clip on the virtual aneurysm neck (8).. Lee and Bang reported a ...
Charcot-Bouchard aneurysm - WikipediaCharcot-Bouchard aneurysm - Wikipedia
Charcot-Bouchard aneurysms (also known as miliary aneurysms or microaneurysms) are aneurysms of the brain vasculature which occur in small blood vessels (less than 300 micrometre diameter). Charcot-Bouchard aneurysms are most often located in the lenticulostriate vessels of the basal ganglia and are associated with chronic hypertension. Charcot-Bouchard aneurysms are a common cause of cerebral hemorrhage. If a Charcot-Bouchard aneurysm ruptures, it will lead to an intracerebral hemorrhage, which can cause hemorrhagic stroke, typically experienced as a sudden focal paralysis or loss of sensation. Charcot-Bouchard aneurysms are aneurysms in the small penetrating blood vessels of the brain. They are associated with hypertension. The common artery involved is the lenticulostriate branch of the middle cerebral artery. Common locations of hypertensive hemorrhages include the putamen, caudate, thalamus, pons, and cerebellum.[citation needed] As with any aneurysm, once formed they have a tendency to ...
PatientsLikeMe | Aneurysm clipping report for patients like youPatientsLikeMe | Aneurysm clipping report for patients like you
Aneurysm clipping: Find the most comprehensive real-world treatment information on Aneurysm clipping at PatientsLikeMe. 1 patients with fibromyalgia, multiple sclerosis, major depressive disorder, generalized anxiety disorder, diabetes type 2, post-traumatic stress disorder, systemic lupus erythematosus, bipolar disorder, Parkinsons disease, panic disorder, rheumatoid arthritis, high blood pressure (hypertension), myalgic encephalomyelitis/chronic fatigue syndrome, persistent depressive disorder (dysthymia), amyotrophic lateral sclerosis, epilepsy, migraine, hypothyroidism, osteoarthritis, traumatic brain injury, bipolar II disorder, attention deficit/hyperactivity disorder, asthma, social anxiety disorder, high cholesterol (hypercholesterolemia), irritable bowel syndrome, idiopathic pulmonary fibrosis, gastroesophageal reflux disease, bipolar I disorder or psoriasis currently have Aneurysm clipping.
Skull with Arteries of the Brain and Berry aneurysm, Lateral View : Medical IllustrationSkull with Arteries of the Brain and Berry aneurysm, Lateral View : Medical Illustration
This stock medical illustration features a right lateral (side) cut-away view through the skull. The dura and main cerebral arteries can be seen along with a small berry aneurysm at the base of the brain cavity.
Social Security Disability Benefits After a Stroke (Page 1) - Law FirmSocial Security Disability Benefits After a Stroke (Page 1) - Law Firm
Many unruptured cerebral aneurysms can now be identified with CTA or MRA, without the more invasive catheter angiography. However, catheter angiography better diagnoses SAH. Angiography of any type is not perfect and can fail to identify small aneurysms of less than 3 mm.. Cerebral aneurysms may be treated surgically to reduce the risk of rupture, rebleeding, or brain damage from pressure the aneurysm places on brain tissue. Surgery to place a metal clip on the neck of an aneurysm that connects it to a parent vessel has been the standard treatment in the past. This procedure is major brain surgery and requires a craniotomy. A piece of the skull (skull flap) is sawed under general anesthesia and laid back for entry into the brain. This surgery has risks and the surgical risks for small aneurysms considerably exceed the risks of conservative (non-surgical) treatment.. A second surgical option has been the use of detachable coils of various sizes and shapes, which can be inserted without opening ...
Is it time to reconsider abdominal aortic aneurysm screening programmes? - CX SymposiumIs it time to reconsider abdominal aortic aneurysm screening programmes? - CX Symposium
Is the rupture rate falling? Janet Powell, London,UK, told delegates that the rate and volume of aneurysm rupture is declining. She made the point that smoking prevalence had decreased, and use of lipid-lowering and antihypertensive drugs had increased in those who were 65+ years. "The small aneurysm rupture rate is decreasing and deaths from (and hospital admissions for) large ruptured aneurysm are decreasing. Since selection for repair and its mortality are unchanged, have cardiovascular risk prevention programmes pre-empted national aneurysm screening programmes?" she asked. Martin Bjorck, Uppsala, Sweden, told delegates that an aneurysm screening programme should include a smoking cessation programme, promotion of exercise and healthy diet and statin treatment prior to surgery. There should also be hypertension treatment, according to standard of care, he said. "As we all know, screening elderly men for abdominal aortic aneurysm, and repair of those who have or later develop large aneurysms, ...
CDKN2BAS gene polymorphisms and the risk of intracranial aneurysm in the Chinese population | BMC Neurology | Full TextCDKN2BAS gene polymorphisms and the risk of intracranial aneurysm in the Chinese population | BMC Neurology | Full Text
CDKN2BAS gene polymorphisms has been shown to correlation with intracranial aneurysm(IA) in the study of foreign people. The study, the author selected the Chinese people as the research object to explore whether CDKN2BAS gene polymorphisms associated with Chinese patients with IA. We selected 200 patients(52.69 ± 11.50) with sporadic IA as experimental group, 200 participants(49.99 ± 13.00) over the same period to the hospital without cerebrovascular diseases as control group. Extraction of peripheral blood DNA, applying polymerase chain reaction(PCR)-ligase detection reaction (LDR) identified CDKN2BAS Single nucleotide polymorphism(SNP) locus genotype: rs6475606, rs1333040, rs10757272, rs3217992, rs974336, rs3217986, rs1063192. The differences in allelic and genotype frequencies between the patient and control groups were evaluated by the chi-square test or Fishers exact tests. The genotype of rs1333040 and rs6475606 shown association with sporadic IA(X2 = 8.545, P = 0.014; X2 = 10.961, P = 0.004;
Hunt and Hess scaleHunt and Hess scale
Tex36Tex36
Piero NatoliPiero Natoli
Subarachnoid hemorrhageSubarachnoid hemorrhage
Hubert Maitland TurnbullHubert Maitland Turnbull
Joshua B. BedersonJoshua B. Bederson
Flow diverterFlow diverter
Neuro-Behçets diseaseNeuro-Behçet's disease
SH3D21SH3D21
CDKN2BASCDKN2BAS
Gazi YaşargilGazi Yaşargil
Hans Petter LangtangenHans Petter Langtangen
James I. AusmanJames I. Ausman
Dong KimDong Kim
Last Gasp (Inside No. 9)Last Gasp (Inside No. 9)
Drotrecogin alfaDrotrecogin alfa
Cerebral arteriovenous malformationCerebral arteriovenous malformation
Soma WeissSoma Weiss
Hybrid operating roomHybrid operating room
Relapsing polychondritisRelapsing polychondritis
HLA-DQ5HLA-DQ5
Subdural hematomaSubdural hematoma
LOXL2LOXL2
DextroscopeDextroscope
LOXL3LOXL3
1975 in Wales1975 in Wales
Trigeminal arteryTrigeminal artery
MMP3MMP3
Endovascular coilingEndovascular coiling
CraniosynostosisCraniosynostosis
Intermittent claudicationIntermittent claudication
Intraparenchymal hemorrhageIntraparenchymal hemorrhage
Hypertensive kidney diseaseHypertensive kidney disease
Strok bahasa Indonesia, ensiklopedia bebasStrok bahasa Indonesia, ensiklopedia bebas
Hypertensive emergencyHypertensive emergency
Head injuryHead injury
Secondary hypertensionSecondary hypertension
Vertebral artery dissectionVertebral artery dissection
Intracranial aneurysmIntracranial aneurysm
List of neurological conditions and disordersList of neurological conditions and disorders
Intracerebral hemorrhageIntracerebral hemorrhage
David FerrieDavid Ferrie
جراحی مغز و اعصاب - ویکی‌پدیا، دانشنامهٔ آزادجراحی مغز و اعصاب - ویکی‌پدیا، دانشنامهٔ آزاد
Pituitary apoplexyPituitary apoplexy
Venous thrombosisVenous thrombosis
Hypertensive heart diseaseHypertensive heart disease
Brain damageBrain damage
ಪಲ್ಮನರಿ ಎಂಬಾಲಿಸಮ್‌ (ಶ್ವಾಸಕೋಶದ ಧಮನಿಬಂಧ) - ವಿಕಿಪೀಡಿಯಪಲ್ಮನರಿ ಎಂಬಾಲಿಸಮ್‌ (ಶ್ವಾಸಕೋಶದ ಧಮನಿಬಂಧ) - ವಿಕಿಪೀಡಿಯ
ICD-10 Chapter IX: Diseases of the circulatory systemICD-10 Chapter IX: Diseases of the circulatory system
BleedingBleeding
Category:Cerebrovascular diseasesCategory:Cerebrovascular diseases
SurgerySurgery
John CurulewskiJohn Curulewski
FedmeFedme
स्नायु शल्यक्रिया - विकिपिडियास्नायु शल्यक्रिया - विकिपिडिया
Laura BraniganLaura Branigan
SurgerySurgery
AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesTechnology, Industry, AgricultureInformation ScienceHealth Care
Intracranial AneurysmAneurysmAneurysm, RupturedCucumisCerebral AngiographySubarachnoid HemorrhageAngiography, Digital SubtractionAneurysm, InfectedAortic AneurysmSurgical InstrumentsMagnetic Resonance AngiographyHeart AneurysmAortic Aneurysm, ThoracicAneurysm, DissectingEndovascular ProceduresRupture, SpontaneousMechanical ThrombolysisNeurosurgical ProceduresTomography, X-Ray ComputedTreatment OutcomeIliac AneurysmImaging, Three-DimensionalCerebral ArteriesCoronary AneurysmBlood Vessel ProsthesisPlatinumStentsGlasgow Outcome ScaleBlood Vessel Prosthesis ImplantationCarotid Artery, InternalVascular Surgical ProceduresBalloon OcclusionAortic RuptureAneurysm, FalseRetreatmentPosterior Cerebral ArteryRetrospective StudiesMicrosurgeryIntracranial ThrombosisAnterior Cerebral ArteryCircle of WillisPostoperative ComplicationsEquipment DesignAorta, AbdominalAngiographyCerebral RevascularizationEquipment Failure AnalysisBasilar ArteryAortographyCarotid Artery DiseasesCoated Materials, BiocompatibleCraniotomyRisk FactorsVertebral ArteryPancreatic ElastaseIntracranial Arteriovenous MalformationsRecurrenceModels, CardiovascularCerebral HemorrhageIntraoperative ComplicationsProsthesis DesignIncidental FindingsSensitivity and SpecificityPolyvinylsLoeys-Dietz SyndromeTime FactorsVasospasm, IntracranialMarfan SyndromeImage Processing, Computer-AssistedNeurologic ExaminationProspective StudiesProstheses and ImplantsOphthalmic ArteryBrain Hemorrhage, TraumaticRadiography, InterventionalIntracranial EmbolismPolycystic Kidney, Autosomal DominantCarotid Artery, Internal, DissectionForeign-Body MigrationTomography, Spiral ComputedRisk AssessmentContrast MediaMagnetic Resonance ImagingCoculture TechniquesPolyarteritis NodosaCatheterizationSubarachnoid SpaceRadiographic Image EnhancementMorbidityHematoma, Subdural, AcuteCerebrovascular CirculationBasal Ganglia HemorrhageDoxycyclineCavernous SinusMiddle Cerebral ArteryMoyamoya DiseaseIliac ArteryOculomotor Nerve DiseasesThromboembolismIncidenceDiastoleReproducibility of ResultsAminocaproatesPedigree
Intracranial aneurysm - WikipediaIntracranial aneurysm - Wikipedia
Intracranial aneurysm - WikipediaIntracranial aneurysm - Wikipedia
Familial Intracranial Aneurysm Study II - Full Text View - ClinicalTrials.govFamilial Intracranial Aneurysm Study II - Full Text View - ClinicalTrials.gov
Flow Diversion in Intracranial Aneurysm Treatment - Full Text View - ClinicalTrials.govFlow Diversion in Intracranial Aneurysm Treatment - Full Text View - ClinicalTrials.gov
Hemodynamics in intracranial aneurysmsHemodynamics in intracranial aneurysms
Search Results for unruptured intracranial aneurysm | jnsSearch Results for "unruptured intracranial aneurysm" | jns
Hemodynamics in Ruptured Intracranial Aneurysms | IntechOpenHemodynamics in Ruptured Intracranial Aneurysms | IntechOpen
MAUDE Adverse Event Report: MICRO THERAPEUTICS, INC. DBA EV3 PIPELINE FLEX EMBOLIZATION DEVICE INTRACRANIAL ANEURYSM FLOW...MAUDE Adverse Event Report: MICRO THERAPEUTICS, INC. DBA EV3 PIPELINE FLEX EMBOLIZATION DEVICE INTRACRANIAL ANEURYSM FLOW...
Flow Diversion for Intracranial Aneurysms | StrokeFlow Diversion for Intracranial Aneurysms | Stroke
Genome-Wide Scan for Japanese Familial Intracranial Aneurysms. Linkage to Several Chromosomal Regions | CirculationGenome-Wide Scan for Japanese Familial Intracranial Aneurysms. Linkage to Several Chromosomal Regions | Circulation
Risk-benefit analysis of the treatment of unruptured intracranial aneurysmsRisk-benefit analysis of the treatment of unruptured intracranial aneurysms
Bailout Stent Deployment during Coil Embolization of Intracranial AneurysmsBailout Stent Deployment during Coil Embolization of Intracranial Aneurysms
Intracranial AneurysmIntracranial Aneurysm
Ruptured intracranial aneurysm: MedlinePlus Medical Encyclopedia ImageRuptured intracranial aneurysm: MedlinePlus Medical Encyclopedia Image
Intracranial Aneurysm CoilIntracranial Aneurysm Coil
Adenosine-Assisted Clipping of Intracranial Aneurysms | SpringerLinkAdenosine-Assisted Clipping of Intracranial Aneurysms | SpringerLink
Infectious intracranial aneurysm - WikipediaInfectious intracranial aneurysm - Wikipedia
Screening for intracranial aneurysms in ADPKD | The BMJScreening for intracranial aneurysms in ADPKD | The BMJ
What are treatment guidelines for unruptured intracranial aneurysms?What are treatment guidelines for unruptured intracranial aneurysms?
Dissecting aneurysms of the intracranial vertebral artery. - PubMed - NCBIDissecting aneurysms of the intracranial vertebral artery. - PubMed - NCBI
Adult polycystic kidney disease and intracranial aneurysms. | The BMJAdult polycystic kidney disease and intracranial aneurysms. | The BMJ
Intracranial AneurysmIntracranial Aneurysm
7T MRA delves deeper into intracranial aneurysms7T MRA delves deeper into intracranial aneurysms
Surgery following endovascular coiling of intracranial aneurysmsSurgery following endovascular coiling of intracranial aneurysms
Recurrence of intracranial aneurysms in autosomal-dominant polycystic kidney disease. - PubMed - NCBIRecurrence of intracranial aneurysms in autosomal-dominant polycystic kidney disease. - PubMed - NCBI
Systematic review of reviews of risk factors for intracranial aneurysmsSystematic review of reviews of risk factors for intracranial aneurysms
CODMAN ENTERPRISE 2 Intracranial Aneurysm Stent Released in U.S. | MedgadgetCODMAN ENTERPRISE 2 Intracranial Aneurysm Stent Released in U.S. | Medgadget
Intracranial aneurysms and connective tissue disordersIntracranial aneurysms and connective tissue disorders
Intracranial aneurysm - Clinical AdvisorIntracranial aneurysm - Clinical Advisor
Study of Antiplatelet Therapy for Intracranial Aneurysm Stent-assisted Coiling - Tabular View - ClinicalTrials.govStudy of Antiplatelet Therapy for Intracranial Aneurysm Stent-assisted Coiling - Tabular View - ClinicalTrials.gov
AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesTechnology, Industry, AgricultureInformation ScienceHealth Care
Intracranial AneurysmAneurysmAneurysm, RupturedCucumisCerebral AngiographySubarachnoid HemorrhageAngiography, Digital SubtractionAneurysm, InfectedAortic AneurysmSurgical InstrumentsMagnetic Resonance AngiographyHeart AneurysmAortic Aneurysm, ThoracicAneurysm, DissectingEndovascular ProceduresRupture, SpontaneousMechanical ThrombolysisNeurosurgical ProceduresTomography, X-Ray ComputedTreatment OutcomeIliac AneurysmImaging, Three-DimensionalCerebral ArteriesCoronary AneurysmBlood Vessel ProsthesisPlatinumStentsGlasgow Outcome ScaleBlood Vessel Prosthesis ImplantationCarotid Artery, InternalVascular Surgical ProceduresBalloon OcclusionAortic RuptureAneurysm, FalseRetreatmentPosterior Cerebral ArteryRetrospective StudiesMicrosurgeryIntracranial ThrombosisAnterior Cerebral ArteryCircle of WillisPostoperative ComplicationsEquipment DesignAorta, AbdominalAngiographyCerebral RevascularizationEquipment Failure AnalysisBasilar ArteryAortographyCarotid Artery DiseasesCoated Materials, BiocompatibleCraniotomyRisk FactorsVertebral ArteryPancreatic ElastaseIntracranial Arteriovenous MalformationsRecurrenceModels, CardiovascularCerebral HemorrhageIntraoperative ComplicationsProsthesis DesignIncidental FindingsSensitivity and SpecificityPolyvinylsLoeys-Dietz SyndromeTime FactorsVasospasm, IntracranialMarfan SyndromeImage Processing, Computer-AssistedNeurologic ExaminationProspective StudiesProstheses and ImplantsOphthalmic ArteryBrain Hemorrhage, TraumaticRadiography, InterventionalIntracranial EmbolismPolycystic Kidney, Autosomal DominantCarotid Artery, Internal, DissectionForeign-Body MigrationTomography, Spiral ComputedRisk AssessmentContrast MediaMagnetic Resonance ImagingCoculture TechniquesPolyarteritis NodosaCatheterizationSubarachnoid SpaceRadiographic Image EnhancementMorbidityHematoma, Subdural, AcuteCerebrovascular CirculationBasal Ganglia HemorrhageDoxycyclineCavernous SinusMiddle Cerebral ArteryMoyamoya DiseaseIliac ArteryOculomotor Nerve DiseasesThromboembolismIncidenceDiastoleReproducibility of ResultsAminocaproatesPedigree
Internal carotiBrain aneurysmAngiographyOcclusionDevelopment of intracranial aneurysmsEmbolizationRisk of ruptureSurgicalHemorrhageBasilar arteryOutcomesPatientsVesselPrevalenceCoilLocation of the aneurysmNeurosurgicalMicrosurgicalComplicationsHemodynamicFamilial Intracranial AneurysmClinicalTreatmentRupturesSymptomsDiagnosis of intracranialAutopsySurgerySmall aneurysms
Internal caroti2
  • The locations of the aneurysms were the internal carotid artery ( n = 12) and basilar artery ( n = 4). (scialert.net)
  • Victor Horsley is credited with being the first surgeon to apply Hunterian ligation of the internal carotid artery for the treatment of an unruptured cerebral aneurysm in 1885 ( Polevaya et al 2006 ). (medlink.com)
Brain aneurysm4
Angiography6
Occlusion4
Development of intracranial aneurysms3
Embolization5
  • Comparative analysis of unruptured cerebral aneurysm treatment outcomes and complications with the classic versus flex pipeline embolization devices and phenom versus marksman microcatheter delivery system: the role of microcatheter choice on complication rate. (fda.gov)
  • Self-expandable stents are an effective tool for coil embolization of wide-neck intracranial aneurysms. (scialert.net)
  • Among 318 aneurysms treated by coil embolization in 267 patients, 16 patients who were treated by bailout stent deployment were retrospectively reviewed. (scialert.net)
  • Bailout self-expandable stent deployment may be a feasible and effective method for relief/prevention of parent artery compromise or coil migration caused by prolapsed or unstable coil loops during embolization of aneurysms. (scialert.net)
  • Flow diverting stents such as the Pipeline embolization device, the SILK device, the surpass flow diverter, the flow redirection endoluminal device, and others are now being investigated or routinely used to treat select anterior circulation aneurysms ( Brouillard et al 2016 ). (medlink.com)
Risk of rupture3
Surgical1
Hemorrhage7
Basilar artery2
Outcomes2
  • The purpose of this article was to evaluate the outcomes of aneurysms treatment with pipeline flex vs. Pipeline classic. (fda.gov)
  • In this article we will review the epidemiology, pathophysiology, diagnostic workup, treatment strategies, and clinical outcomes that should be considered prior to making management decisions regarding unruptured cerebral aneurysms. (medlink.com)
Patients13
Vessel2
Prevalence2
Coil1
Location of the aneurysm1
  • The size/location of the aneurysm, technical feasibility, successful stabilization rate, and procedure-related complications were evaluated. (scialert.net)
Neurosurgical1
Microsurgical1
Complications2
Hemodynamic1
Familial Intracranial Aneurysm2
  • The Familial Intracranial Aneurysm Study is a collaborative research effort of neurologists and neurosurgeons throughout the United States, Canada, Australia and New Zealand to identify possible genes that may increase the risk of stroke, and particularly, the development of aneurysms in the blood vessels of the brain. (clinicaltrials.gov)
  • This study of affected individuals and families, known as the Familial Intracranial Aneurysm (FIA) study, is sponsored by the National Institutes of Health and has involved over 475 families. (clinicaltrials.gov)
Clinical2
Treatment3
Ruptures2
  • Before a larger aneurysm ruptures, the individual may experience such symptoms as a sudden and unusually severe headache, nausea , vision impairment, vomiting , and loss of consciousness , or the individual may experience no symptoms at all. (wikipedia.org)
  • If an aneurysm ruptures, blood leaks into the space around the brain. (wikipedia.org)
Symptoms7
Diagnosis of intracranial1
Autopsy1
Surgery2
Small aneurysms1
Aspirin May Decrease Intracranial Aneurysm Growth
Aspirin May Decrease Intracranial Aneurysm Growth (medscape.com)
Polycystic Kidney Disease Workup: Approach Considerations, Ultrasonography, CT, MRI, and MRA
Polycystic Kidney Disease Workup: Approach Considerations, Ultrasonography, CT, MRI, and MRA (emedicine.medscape.com)
Stroke Conditions - Emory Healthcare
Stroke Conditions - Emory Healthcare (emoryhealthcare.org)
Brain Aneurysm - Health Library
Brain Aneurysm - Health Library (healthlibrary.epnet.com)
Adenosine-Assisted Clipping of Intracranial Aneurysms | SpringerLink
Adenosine-Assisted Clipping of Intracranial Aneurysms | SpringerLink (link.springer.com)
Bilateral visual loss caused by an intracranial aneurysm | CMAJ
Bilateral visual loss caused by an intracranial aneurysm | CMAJ (cmaj.ca)
Antidepressant Use After Aneurysmal Subarachnoid Hemorrhage | Stroke
Antidepressant Use After Aneurysmal Subarachnoid Hemorrhage | Stroke (stroke.ahajournals.org)
Jamaica Health, Beauty, Weddings & Motherhood Stories for the Jamaican Woman - Jamaica Observer - All Woman - JamaicaObserver...
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Stroke/Vascular Services - CentraCare Health, Central Minnesota
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The Management of Intracranial Aneurysm in: Journal of Neurosurgery Volume 19 Issue 1 (1962)
The Management of Intracranial Aneurysm in: Journal of Neurosurgery Volume 19 Issue 1 (1962) (thejns.org)
Search Results | jns
Search Results | jns (thejns.org)
Published Ahead-of-Print : Neurosurgery Quarterly
Published Ahead-of-Print : Neurosurgery Quarterly (journals.lww.com)
Aspirin News, Research
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Intracranial Aneurysm Market Size Worth $1.92 Billion By 2027 | CAGR: 8.8%: Grand View Research, Inc.
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How Does Polycystic Kidney Disease Affect the Kidneys? Symptoms
How Does Polycystic Kidney Disease Affect the Kidneys? Symptoms (emedicinehealth.com)
Mri brain anatomy Dr Muhammad Bin Zulfiqar - English
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Plus it
Plus it (cmaj.ca)
QUT - Student topics
QUT - Student topics (qut.edu.au)
Trends in the Management of Cerebrovascular Diseases | Springer for Research & Development
Trends in the Management of Cerebrovascular Diseases | Springer for Research & Development (rd.springer.com)
Current Medicinal Chemistry, Volume 21 - Number 37
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7T MRA delves deeper into intracranial aneurysms
7T MRA delves deeper into intracranial aneurysms (auntminnie.com)
Ruptured intracranial aneurysm: MedlinePlus Medical Encyclopedia Image
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Handbook of Cerebrovascular Disease and Neurointerventional Technique | SpringerLink
Handbook of Cerebrovascular Disease and Neurointerventional Technique | SpringerLink (link.springer.com)
Contrast-free Magnetic Resonance Angiography (MRA) at 3.0 T for Intracranial Aneurysm Detection - Full Text View -...
Contrast-free Magnetic Resonance Angiography (MRA) at 3.0 T for Intracranial Aneurysm Detection - Full Text View -... (clinicaltrials.gov)
Radiology News, Research - Page 222
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June 1994 - Volume 4 - Issue 2 - Contributor Index : Neurosurgery Quarterly
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