Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (>2.5 cm in diameter) may compress adjacent structures, including the OCULOMOTOR NERVE. (From Adams et al., Principles of Neurology, 6th ed, p841)
Pathological outpouching or sac-like dilatation in the wall of any blood vessel (ARTERIES or VEINS) or the heart (HEART ANEURYSM). It indicates a thin and weakened area in the wall which may later rupture. Aneurysms are classified by location, etiology, or other characteristics.
The tearing or bursting of the weakened wall of the aneurysmal sac, usually heralded by sudden worsening pain. The great danger of a ruptured aneurysm is the large amount of blood spilling into the surrounding tissues and cavities, causing HEMORRHAGIC SHOCK.
A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage.
Radiography of the vascular system of the brain after injection of a contrast medium.
Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.
A method of delineating blood vessels by subtracting a tissue background image from an image of tissue plus intravascular contrast material that attenuates the X-ray photons. The background image is determined from a digitized image taken a few moments before injection of the contrast material. The resulting angiogram is a high-contrast image of the vessel. This subtraction technique allows extraction of a high-intensity signal from the superimposed background information. The image is thus the result of the differential absorption of X-rays by different tissues.
Aneurysm due to growth of microorganisms in the arterial wall, or infection arising within preexisting arteriosclerotic aneurysms.
An abnormal balloon- or sac-like dilatation in the wall of AORTA.
Hand-held tools or implements used by health professionals for the performance of surgical tasks.
Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.
A localized bulging or dilatation in the muscle wall of a heart (MYOCARDIUM), usually in the LEFT VENTRICLE. Blood-filled aneurysms are dangerous because they may burst. Fibrous aneurysms interfere with the heart function through the loss of contractility. True aneurysm is bound by the vessel wall or cardiac wall. False aneurysms are HEMATOMA caused by myocardial rupture.
An abnormal balloon- or sac-like dilatation in the wall of the THORACIC AORTA. This proximal descending portion of aorta gives rise to the visceral and the parietal branches above the aortic hiatus at the diaphragm.
Aneurysm caused by a tear in the TUNICA INTIMA of a blood vessel leading to interstitial HEMORRHAGE, and splitting (dissecting) of the vessel wall, often involving the AORTA. Dissection between the intima and media causes luminal occlusion. Dissection at the media, or between the media and the outer adventitia causes aneurismal dilation.
Minimally invasive procedures, diagnostic or therapeutic, performed within the BLOOD VESSELS. They may be perfomed via ANGIOSCOPY; INTERVENTIONAL MAGNETIC RESONANCE IMAGING; INTERVENTIONAL RADIOGRAPHY; or INTERVENTIONAL ULTRASONOGRAPHY.
Tear or break of an organ, vessel or other soft part of the body, occurring in the absence of external force.
Procedures to cause the disintegration of THROMBI by physical interventions.
Surgery performed on the nervous system or its parts.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Abnormal balloon- or sac-like dilatation in the wall of any one of the iliac arteries including the common, the internal, or the external ILIAC ARTERY.
The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.
The arterial blood vessels supplying the CEREBRUM.
Abnormal balloon- or sac-like dilatation in the wall of CORONARY VESSELS. Most coronary aneurysms are due to CORONARY ATHEROSCLEROSIS, and the rest are due to inflammatory diseases, such as KAWASAKI DISEASE.
Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels.
Platinum. A heavy, soft, whitish metal, resembling tin, atomic number 78, atomic weight 195.09, symbol Pt. (From Dorland, 28th ed) It is used in manufacturing equipment for laboratory and industrial use. It occurs as a black powder (platinum black) and as a spongy substance (spongy platinum) and may have been known in Pliny's time as "alutiae".
Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.
A scale that assesses the outcome of serious craniocerebral injuries, based on the level of regained social functioning.
Surgical insertion of BLOOD VESSEL PROSTHESES to repair injured or diseased blood vessels.
Branch of the common carotid artery which supplies the anterior part of the brain, the eye and its appendages, the forehead and nose.
Operative procedures for the treatment of vascular disorders.
Use of a balloon CATHETER to block the flow of blood through an artery or vein.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
The tearing or bursting of the wall along any portion of the AORTA, such as thoracic or abdominal. It may result from the rupture of an aneurysm or it may be due to TRAUMA.
Not an aneurysm but a well-defined collection of blood and CONNECTIVE TISSUE outside the wall of a blood vessel or the heart. It is the containment of a ruptured blood vessel or heart, such as sealing a rupture of the left ventricle. False aneurysm is formed by organized THROMBUS and HEMATOMA in surrounding tissue.
The therapy of the same disease in a patient, with the same agent or procedure repeated after initial treatment, or with an additional or alternate measure or follow-up. It does not include therapy which requires more than one administration of a therapeutic agent or regimen. Retreatment is often used with reference to a different modality when the original one was inadequate, harmful, or unsuccessful.
Artery formed by the bifurcation of the BASILAR ARTERY. Branches of the posterior cerebral artery supply portions of the OCCIPITAL LOBE; PARIETAL LOBE; inferior temporal gyrus, brainstem, and CHOROID PLEXUS.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
The performance of surgical procedures with the aid of a microscope.
Formation or presence of a blood clot (THROMBUS) in a blood vessel within the SKULL. Intracranial thrombosis can lead to thrombotic occlusions and BRAIN INFARCTION. The majority of the thrombotic occlusions are associated with ATHEROSCLEROSIS.
Artery formed by the bifurcation of the internal carotid artery (CAROTID ARTERY, INTERNAL). Branches of the anterior cerebral artery supply the CAUDATE NUCLEUS; INTERNAL CAPSULE; PUTAMEN; SEPTAL NUCLEI; GYRUS CINGULI; and surfaces of the FRONTAL LOBE and PARIETAL LOBE.
A polygonal anastomosis at the base of the brain formed by the internal carotid (CAROTID ARTERY, INTERNAL), proximal parts of the anterior, middle, and posterior cerebral arteries (ANTERIOR CEREBRAL ARTERY; MIDDLE CEREBRAL ARTERY; POSTERIOR CEREBRAL ARTERY), the anterior communicating artery and the posterior communicating arteries.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
Methods of creating machines and devices.
The aorta from the DIAPHRAGM to the bifurcation into the right and left common iliac arteries.
Radiography of blood vessels after injection of a contrast medium.
Microsurgical revascularization to improve intracranial circulation. It usually involves joining the extracranial circulation to the intracranial circulation but may include extracranial revascularization (e.g., subclavian-vertebral artery bypass, subclavian-external carotid artery bypass). It is performed by joining two arteries (direct anastomosis or use of graft) or by free autologous transplantation of highly vascularized tissue to the surface of the brain.
The evaluation of incidents involving the loss of function of a device. These evaluations are used for a variety of purposes such as to determine the failure rates, the causes of failures, costs of failures, and the reliability and maintainability of devices.
The artery formed by the union of the right and left vertebral arteries; it runs from the lower to the upper border of the pons, where it bifurcates into the two posterior cerebral arteries.
Radiographic visualization of the aorta and its branches by injection of contrast media, using percutaneous puncture or catheterization procedures.
Pathological conditions involving the CAROTID ARTERIES, including the common, internal, and external carotid arteries. ATHEROSCLEROSIS and TRAUMA are relatively frequent causes of carotid artery pathology.
Biocompatible materials usually used in dental and bone implants that enhance biologic fixation, thereby increasing the bond strength between the coated material and bone, and minimize possible biological effects that may result from the implant itself.
Any operation on the cranium or incision into the cranium. (Dorland, 28th ed)
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
The first branch of the SUBCLAVIAN ARTERY with distribution to muscles of the NECK; VERTEBRAE; SPINAL CORD; CEREBELLUM; and interior of the CEREBRUM.
A protease of broad specificity, obtained from dried pancreas. Molecular weight is approximately 25,000. The enzyme breaks down elastin, the specific protein of elastic fibers, and digests other proteins such as fibrin, hemoglobin, and albumin. EC 3.4.21.36.
Congenital vascular anomalies in the brain characterized by direct communication between an artery and a vein without passing through the CAPILLARIES. The locations and size of the shunts determine the symptoms including HEADACHES; SEIZURES; STROKE; INTRACRANIAL HEMORRHAGES; mass effect; and vascular steal effect.
The return of a sign, symptom, or disease after a remission.
Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.
Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA.
Complications that affect patients during surgery. They may or may not be associated with the disease for which the surgery is done, or within the same surgical procedure.
The plan and delineation of prostheses in general or a specific prosthesis.
Unanticipated information discovered in the course of testing or medical care. Used in discussions of information that may have social or psychological consequences, such as when it is learned that a child's biological father is someone other than the putative father, or that a person tested for one disease or disorder has, or is at risk for, something else.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
An autosomal dominant aneurysm with multisystem abnormalities caused by increased TGF-BETA signaling due to mutations in type I or II of TGF-BETA RECEPTOR. Additional craniofacial features include CLEFT PALATE; CRANIOSYNOSTOSIS; HYPERTELORISM; or bifid uvula. Phenotypes closely resemble MARFAN SYNDROME; Marfanoid craniosynostosis syndrome (Shprintzen-Goldberg syndrome); and EHLERS-DANLOS SYNDROME.
Elements of limited time intervals, contributing to particular results or situations.
Constriction of arteries in the SKULL due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and BRAIN ISCHEMIA that may lead to hypoxic-ischemic brain injury (HYPOXIA-ISCHEMIA, BRAIN).
An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome is associated with mutations in the gene encoding fibrillin, a major element of extracellular microfibrils of connective tissue.
A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.
Assessment of sensory and motor responses and reflexes that is used to determine impairment of the nervous system.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally.
Artery originating from the internal carotid artery and distributing to the eye, orbit and adjacent facial structures.
Bleeding within the brain as a result of penetrating and nonpenetrating CRANIOCEREBRAL TRAUMA. Traumatically induced hemorrhages may occur in any area of the brain, including the CEREBRUM; BRAIN STEM (see BRAIN STEM HEMORRHAGE, TRAUMATIC); and CEREBELLUM.
Diagnostic and therapeutic procedures that are invasive or surgical in nature, and require the expertise of a specially trained radiologist. In general, they are more invasive than diagnostic imaging but less invasive than major surgery. They often involve catheterization, fluoroscopy, or computed tomography. Some examples include percutaneous transhepatic cholangiography, percutaneous transthoracic biopsy, balloon angioplasty, and arterial embolization.
Blocking of a blood vessel in the SKULL by an EMBOLUS which can be a blood clot (THROMBUS) or other undissolved material in the blood stream. Most emboli are of cardiac origin and are associated with HEART DISEASES. Other non-cardiac sources of emboli are usually associated with VASCULAR DISEASES.
Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.
Kidney disorders with autosomal dominant inheritance and characterized by multiple CYSTS in both KIDNEYS with progressive deterioration of renal function.
The splitting of the vessel wall in one or both (left and right) internal carotid arteries (CAROTID ARTERY, INTERNAL). Interstitial hemorrhage into the media of the vessel wall can lead to occlusion of the internal carotid artery and aneurysm formation.
Migration of a foreign body from its original location to some other location in the body.
Computed tomography where there is continuous X-ray exposure to the patient while being transported in a spiral or helical pattern through the beam of irradiation. This provides improved three-dimensional contrast and spatial resolution compared to conventional computed tomography, where data is obtained and computed from individual sequential exposures.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
Substances used to allow enhanced visualization of tissues.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
A form of necrotizing non-granulomatous inflammation occurring primarily in medium-sized ARTERIES, often with microaneurysms. It is characterized by muscle, joint, and abdominal pain resulting from arterial infarction and scarring in affected organs. Polyarteritis nodosa with lung involvement is called CHURG-STRAUSS SYNDROME.
Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.
The space between the arachnoid membrane and PIA MATER, filled with CEREBROSPINAL FLUID. It contains large blood vessels that supply the BRAIN and SPINAL CORD.
Improvement in the quality of an x-ray image by use of an intensifying screen, tube, or filter and by optimum exposure techniques. Digital processing methods are often employed.
The proportion of patients with a particular disease during a given year per given unit of population.
Accumulation of blood in the SUBDURAL SPACE with acute onset of neurological symptoms. Symptoms may include loss of consciousness, severe HEADACHE, and deteriorating mental status.
The circulation of blood through the BLOOD VESSELS of the BRAIN.
Bleeding within the subcortical regions of cerebral hemispheres (BASAL GANGLIA). It is often associated with HYPERTENSION or ARTERIOVENOUS MALFORMATIONS. Clinical manifestations may include HEADACHE; DYSKINESIAS; and HEMIPARESIS.
A synthetic tetracycline derivative with similar antimicrobial activity.
An irregularly shaped venous space in the dura mater at either side of the sphenoid bone.
The largest of the cerebral arteries. It trifurcates into temporal, frontal, and parietal branches supplying blood to most of the parenchyma of these lobes in the CEREBRAL CORTEX. These are the areas involved in motor, sensory, and speech activities.
A noninflammatory, progressive occlusion of the intracranial CAROTID ARTERIES and the formation of netlike collateral arteries arising from the CIRCLE OF WILLIS. Cerebral angiogram shows the puff-of-smoke (moyamoya) collaterals at the base of the brain. It is characterized by endothelial HYPERPLASIA and FIBROSIS with thickening of arterial walls. This disease primarily affects children but can also occur in adults.
Either of two large arteries originating from the abdominal aorta; they supply blood to the pelvis, abdominal wall and legs.
Diseases of the oculomotor nerve or nucleus that result in weakness or paralysis of the superior rectus, inferior rectus, medial rectus, inferior oblique, or levator palpebrae muscles, or impaired parasympathetic innervation to the pupil. With a complete oculomotor palsy, the eyelid will be paralyzed, the eye will be in an abducted and inferior position, and the pupil will be markedly dilated. Commonly associated conditions include neoplasms, CRANIOCEREBRAL TRAUMA, ischemia (especially in association with DIABETES MELLITUS), and aneurysmal compression. (From Adams et al., Principles of Neurology, 6th ed, p270)
Obstruction of a blood vessel (embolism) by a blood clot (THROMBUS) in the blood stream.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
Postoperative hemorrhage from an endovascular AORTIC ANEURYSM repaired with endoluminal placement of stent grafts (BLOOD VESSEL PROSTHESIS IMPLANTATION). It is associated with pressurization, expansion, and eventual rupture of the aneurysm.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Amino derivatives of caproic acid. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the amino caproic acid structure.
The record of descent or ancestry, particularly of a particular condition or trait, indicating individual family members, their relationships, and their status with respect to the trait or condition.

3D angiography. Clinical interest. First applications in interventional neuroradiology. (1/2536)

3D angiography is a true technical revolution that allows improvement in the quality and safety of diagnostic and endovascular treatment procedures. 3D angiography images are obtained by reconstruction of a rotational angiography acquisition done on a C-arm (GE Medical Systems) spinning at 40 degrees per second. The carotid or vertebral selective injection of a total of 15 ml of non-ionic contrast media at 3 ml/sec over 5 seconds allows the selection of the "arterial phase". Four hundred sixty 3D angiographic studies were performed from December 1996 to September 1998 on 260 patients and have been analyzed in MIP (Maximum Intensity Projection) and SSD (Shaded Surface Display) views. The exploration of intracranial aneurysms is simplified and only requires, for each vascular axis, a biplane PA and Lateral run followed by a single rotational angiography run. The 3D angiography image is available on the workstation's screen (Advantage Workstation 3.1, GE Medical Systems) in less than 10 minutes after the acquisition of the rotational run. It therefore allows one to analyze, during the intervention, the aneurysm's angioarchitecture, in particular the neck, and select the best therapeutic technique. When endovascular treatment is the best indication, 3D angiography allows one to define the optimal angle of view and accurately select the microcoils dimensions. 3D angiography replaces the multiple oblique views that used to be required to analyze the complex aneurysms and therefore allows a reduction of the total contrast medium quantity, the patient X-ray dose and the length of the intervention time which is a safety factor. Also, in particular for complex cases, it brings additional elements complementing the results of standard 2D DSA and rotational angiograms. In the cervical vascular pathology, 3D angiography allows for a better assessment of the stenosis level and of dissection lesions. Our current research activities focus on the matching without stereotactic frame between 3D X-ray angiography and volumetric MR acquisition, which should allow us to improve the treatment of intracerebral arterio-venous malformations (AVMs).  (+info)

Combination therapy of fasudil hydrochloride and ozagrel sodium for cerebral vasospasm following aneurysmal subarachnoid hemorrhage. (2/2536)

Fasudil hydrochloride is a new type of intracellular calcium antagonist, different from the calcium entry blockers that are commonly employed for clinical use. Since September 1995, the combination of fasudil hydrochloride and ozagrel sodium, an inhibitor of thromboxane A2 synthesis, has been used to treat 60 patients at risk of cerebral vasospasm after aneurysmal subarachnoid hemorrhage. The effectiveness of this combination therapy was investigated by comparison with the outcome of 57 patients previously treated with only ozagrel sodium. The combination therapy was significantly more effective (p < 0.01) in reducing the incidence of low density areas on computed tomography scans, and reduced, but not significantly, the occurrence of symptomatic vasospasm. The combination therapy of fasudil hydrochloride and ozagrel sodium has superior effectiveness over only ozagrel sodium in treating patients at risk of vasospasm after aneurysmal subarachnoid hemorrhage.  (+info)

Large and giant middle to lower basilar trunk aneurysms treated by surgical and interventional neuroradiological methods. (3/2536)

Treatment of large and giant aneurysms of the basilar artery remains difficult and controversial. Three large or giant aneurysms of the lower basilar artery were treated with a combination of surgical and interventional neuroradiological procedures. All patients underwent the balloon occlusion test with hypotensive challenge (blood pressure reduced to 70% of the control value). The third patient did not tolerate the test. In the first patient, both vertebral arteries were occluded through a craniotomy. In the second patient, both the aneurysm and the basilar artery were occluded by detached balloons. In the third patient, one vertebral artery was occluded by surgical clipping and the other by detached helical coils and fiber coils. In spite of anti-coagulation and anti-platelet therapy, postoperative thrombotic or embolic ischemia occurred in the second and third patients. Fibrinolytic therapy promptly corrected the ischemic symptoms, but the second patient developed hemorrhagic complications at the craniotomy area 2 hours later. At follow-up examination, the first patient had only 8th cranial nerve paresis, the second patient who had a hemorrhagic complication was bed-ridden, and the third patient had no deficit. Interventional occlusion requires a longer segment of the parent artery compared to surgical occlusion of the parent artery and might cause occlusion of the perforating arteries. However, selected use of various coils can occlude only a short segment of the parent artery. Thus, the postoperative management of thromboembolic ischemia after the occlusion of the parent artery is easier using the interventional technique.  (+info)

Significance of acute cerebral swelling in patients with sylvian hematoma due to ruptured middle cerebral artery aneurysm, and its management. (4/2536)

A retrospective study of 75 patients treated surgically for ruptured middle cerebral artery (MCA) aneurysm within 48 hours evaluated clinical grade at admission, secondary development and management of cerebral swelling associated with space-occupying hematoma, cerebral infarction caused by vasospasm, development of hydrocephalus, and clinical outcome. Clinical grade at admission was significantly better in patients without than in those with hematoma (p < 0.01). Twenty-seven patients with sylvian hematoma caused by ruptured MCA aneurysm often developed ipsilateral cerebral swelling in the early period after subarachnoid hemorrhage. Seventeen of these patients developed serious cerebral swelling and received barbiturate therapy. Nine of these 17 patients had good outcome, but six patients died of cerebral swelling. The incidence of hydrocephalus was significantly higher in patients with than in those without hematoma (p < 0.01). The incidence of infarction was more pronounced in patients with sylvian hematoma. Clinical outcome was significantly better in patients without than in those with sylvian hematoma (p < 0.01). Development of cerebral swelling in patients with sylvian hematoma due to ruptured MCA aneurysm has a significant effect on outcome, and improvements in management are required.  (+info)

Rupture mechanism of a thrombosed slow-growing giant aneurysm of the vertebral artery--case report. (5/2536)

A 76-year-old male developed left hemiparesis in July 1991. The diagnosis was thrombosed giant vertebral artery aneurysm. He showed progressive symptoms and signs of brainstem compression, but refused surgery and was followed up without treatment. He died of rupture of the aneurysm and underwent autopsy in March 1995. Histological examination of the aneurysm revealed fresh clot in the aneurysmal lumen, old thrombus surrounding the aneurysmal lumen, and more recent hemorrhage between the old thrombus and the inner aneurysmal wall. The most important histological feature was the many clefts containing fresh blood clots in the old thrombus near the wall of the distal neck. These clefts were not lined with endothelial cells, and seemed to connect the lumen of the parent artery with the most peripheral fresh hemorrhage. However, the diameter of each of these clefts is apparently not large enough to transmit the blood pressure of the parent artery. Simple dissection of the aneurysmal wall by blood flow in the lumen through many clefts in the old thrombus of the distal neck may be involved in the growth and rupture of thrombosed giant aneurysms of the vertebral artery.  (+info)

Primary non-traumatic intracranial hemorrhage. A municipal emergency hospital viewpoint. (6/2536)

The devastating natural history of 138 consecutive admissions for non-traumatic intracranial hemorrhage to a major emergency care municipal hospital is reviewed. Sixty-four percent of the patients had demonstrable intracranial hematomas while 36% had mainly subarachnoid hemorrhage. Hypertension was a related condition in 43% of the parenchymal hematoma patients, while proved aneurysms accounted for 74% of the subarachnoid hemorrhage patients. There was only a 14% survivorship for patients requiring emergent surgery. All operated hematoma patients survived delayed surgery with improved level of responsiveness. The overall mortality was 74% for intracranial hematoma patients and 58% for aneurysm-caused subarachnoid hemorrhage patients.  (+info)

The use of electrophysiological monitoring in the intraoperative management of intracranial aneurysms. (7/2536)

OBJECTIVES: Somatosensory evoked potentials (SSEPs) and brainstem auditory evoked potentials (BAEPs) have been increasingly utilised during surgery for intracranial aneurysms to identify cerebral ischaemia. Between July 1994 and April 1996, we surgically treated 70 aneurysms in 49 consecutive patients (58 operations) with the aid of intraoperative evoked potential monitoring. This study sought to evaluate the usefulness of SSEP and BAEP monitoring during intracranial aneurysm surgery. METHODS: Mean patient age was 51.9 (range 18-79) years. The sizes of the aneurysms were 3-4 mm (15), 5-9 mm (26), 10-14 mm (11), 15-19 mm (seven), 20-24 mm (six), and >25 mm (five). SSEPs were monitored in 58 procedures (100%) and BAEPs in 15 (26%). The neurological status of the patients was evaluated before and after surgery. RESULTS: Thirteen of the 58 procedures (22%) monitored with SSEPs had SSEP changes (12 transient, one persistent); 45 (78%) had no SSEP changes. Three of 15 patients (20%) monitored with BAEPs had changes (two transient, one persistent); 12 (80%) had no BAEP changes. Of the 14 patients with transient SSEP or BAEP changes, these changes resolved with adjustment or removal of aneurysm clips (nine), elevating MAP (four), or retractor adjustment (one). Mean time from precipitating event to electrophysiological change was 8.9 minutes (range 3-32), and the mean time for recovery of potentials in patients with transient changes was 20.2 minutes (range 3-60). Clinical outcome was excellent in 39 patients, good in five, and poor in three (two patients died), and was largely related to pretreatment grade. CONCLUSIONS: SSEPs and BAEPs are useful in preventing clinical neurological injury during surgery for intracranial aneurysms and in predicting which patients will have unfavourable outcomes.  (+info)

Cerebral arterial lesions resulting from inflammatory emboli. (8/2536)

In order to study the effects of septic embolism on the brain, silicone rubber emboli of various types were injected into the carotid arteries of 35 dogs. Pathologic and angiographic studies were performed to assess the resultant arterial and parenchymal lesions. Pure silicone rubber emboli (14 dogs) produced occasional intra-arterial thrombosis but no arteritis. Sterile and bacterially contaminated emboli containing a lead-chromate pigment (similar to those used in previous studies of septic embolism) (11 dogs) and pure silicone rubber emboli with transversely oriented canals (10 dogs), after brief placement in a bacterial suspension, were associated with intense inflammatory arteritis. This was accompanied by focal meningitis, subarachnoid hemorrhage, thrombosis, and cerebritis of the underlying cortex. The findings resembled those found in mycotic aneurysm. Aneurysmal dilatation was observed in one postmortem angiogram. In previous models of mycotic aneurysm, the inflammation attributed to bacterial contamination was probably due to the lead-chromate pigment used.  (+info)

Intracranial aneurysms are blisters which form within the arteries at the base of the brain. A rupture of an aneurysm may lead to subarachnoid hemorrhage (SAH). The mortality rates of patients suffering from a SAH is 40 to 44 percent , with many survivors enduring major disability. Most of the deaths from SAH are due to rapid and massive brain injury from the initial bleeding, which is not correctable by medical and surgical intervention. Thus, prevention of aneurysm formation is of paramount importance.. Scientific evidence suggests that a genetic component plays an important role in the development of intracranial aneurysms, however the specific genes have not been identified. The Familial Intracranial Aneurysm Study is a collaborative research effort of neurologists and neurosurgeons throughout the United States, Canada, Australia and New Zealand to identify possible genes that may increase the risk of stroke, and particularly, the development of aneurysms in the blood vessels of the brain. ...
Objectives: To determine under what circumstances repair of unruptured intracranial aneurysms may be beneficial. Methods: A life expectancy analysis of patients with unruptured aneurysms with and without repair based on prospective data from the International Study of Unruptured Intracranial Aneurysms (ISUIA). Results: Life years are lost at all ages by repairing anterior circulation aneurysms under 7 mm in diameter in patients with no history of a subarachnoid haemorrhage from another aneurysm (incidental). For all other aneurysms the number of life years saved by repair is dependent on the patients age at the time when repair is undertaken. Between 2 and 40 years are saved by repairing aneurysms in patients aged 20 years. These benefits fall to 0 when remaining life expectancy falls below 15-35 years, corresponding to the age range of 45-70 years. Conclusions: Repair of unruptured aneurysms benefits patients harbouring them by improving life expectancy except in certain circumstances. The ...
Legendary rapper Dr. Dre was hospitalized on Tuesday after reportedly suffering a brain aneurysm, which can quickly turn deadly should it rupture. Clipping has been shown to be highly effective, depending on the location, size, and shape of the aneurysm. The work provides guidance on avoiding complications as well as anticipating and managing problems that may arise during surgery. The saccular aneurysm, which poses a high risk of rupture, is clipped. 93 people follow this. Tulane physicians are leaders in research and clinical trials to improve treatment for brain aneurysms and stroke. Brain aneurysm clipping is one of the most common treatments for non-emergency aneurysms. … of 17 . What are the symptoms of a Brain Aneurysm, and how is a Brain Aneurysm diagnosed? More than 50 percent of the patients … Help us improve your search experience.Send feedback. 93 people like this. (NEXSTAR) - Dr. Dre has suffered a brain aneurysm, according to multiple reports. See brain aneurysm stock video ...
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Brain aneurysm repair is a surgical procedure used to treat a bulging blood vessel in the brain thats at risk of rupturing or tearing open. In general, most brain aneurysms are small, rarely cause symptoms and have a very low risk of rupture. Feb 8, 2016 - My precious friend Peggy lost her life at 58 years of age to a Brain Aneurysm. The brain has very high oxygen and nutrient requirements and the flow of blood to the brain is critical. Symptoms may occur if the aneurysm is large or if it causes pressure on the structures, such as nerves or meninges (the three-layered covering over the brain), around it. About brain aneurysms. Brain aneurysm repair is surgery to correct an aneurysm. top. Researchers found that straining to defecate can cause over a seven-fold increase in the risk of a brain bleed. Women are more likely than men to develop brain aneurysms. Unruptured intracranial aneurysms (UIAs) are relatively common in the general population, found in and estimated … However, a brain ...
Intracranial aneurysm, also known as brain aneurysm, is a cerebrovascular disorder in which weakness in the wall of a cerebral artery or vein causes a localized dilation or ballooning of the blood vessel. Aneurysms in the posterior circulation (basilar artery, vertebral arteries and posterior communicating artery) have a higher risk of rupture. Basilar artery aneurysms represent only 3%-5% of all intracranial aneurysms but are the most common aneurysms in the posterior circulation. Cerebral aneurysms are classified both by size and shape. Small aneurysms have a diameter of less than 15 mm. Larger aneurysms include those classified as large (15 to 25 mm), giant (25 to 50 mm), and super-giant (over 50 mm). Saccular aneurysms, also known as berry aneurysms, appear as a round outpouching and are the most common form of cerebral aneurysm. Fusiform dolichoectatic aneurysms represent a widening of a segment of an artery around the entire blood vessel, rather than just arising from a side of an arterys ...
Although lot of studies have been conducted to examine the association of genetic polymorphism and intracranial aneurysms, the relationship between the APOE polymorphism and intracranial aneurysms has previously only been studied in Russia and Japan but not in Chinese populations [13, 14]. Evidence from a case-control study suggested that the collagen type I alpha2 gene polymorphism was associated with intracranial aneurysms in a subset of the German population [15]. Authors of a case-control study suggested that the IL-12A and IL-12B independently and jointly was involved in the susceptibility to intracranial aneurysms in a Chinese population [16]. Evidence from a meta-analysis included six case-control studies, which included 1188 intracranial aneurysms cases and 4099 controls, suggested that IL-6 promoter polymorphisms (-174G/C and -572G/C) were associated with intracranial aneurysms [17]. Authors of a case-control study in a Chinese population suggested that the miR-34b/c rs4938723CC and ...
The PED is a flexible, braided wire mesh tube which can be placed within the internal carotid artery in the brain, blocking off large or wide-necked aneurysms. The device can also reduce the likelihood that an aneurysm will rupture. The Pipeline® Embolization Device offers neurointerventional surgeons a minimally invasive alternative to open surgery or placement of materials such as coils or a liquid embolic when treating carotid artery brain aneurysms, said Avi Setton, MD, chief of interventional neuroradiology at North Shore University Hospital. While coiling can be effective for small brain aneurysms, it does not always work on larger ones. The PED device offers patients a better chance of long-lasting aneurysm occlusion and low complication rates.. In the endovascular procedure, the PED is threaded up through a catheter placed in a blood vessel in the leg, up to the brain. The PED is implanted across the neck of the aneurysm, cutting off blood flow. The blood that remains in the ...
In the article PCNT point mutations and familial intracranial aneurysms by Lorenzo-Betancor et al.,1 published online ahead of print on November 9, 2018, Dr. Lorenzo-Betancors affiliations should have included the Veterans Affairs Puget Sound Health Care System and the University of Washington. The Disclosures section should have included: O. Lorenzo-Betancor was supported in part by a postdoctoral fellowship award from the Department of Veterans Affairs. In the Results section of the abstract, the value should read p.V2811L. Finally, in the abbreviations for figure 2, Pact should read pericentrin-AKAP-450…. These items appear correctly in the December 4, 2018, issue. The publisher regrets the errors.. ...
TY - JOUR. T1 - The true distal posterior inferior cerebellar artery aneurysm. T2 - Clinical characteristics and strategy for treatment. AU - Zhou, Y.. AU - Kato, Y.. AU - Olugbenga, O. T.. AU - Hirotoshi, S.. AU - Karagiozov, K.. AU - Masahiro, O.. AU - Amitendu, S.. AU - Makoto, N.. AU - Tetsuo, K.. PY - 2010. Y1 - 2010. N2 - Objective: A series of aneurysms located at the 4th or 5 th segment of the posterior inferior cerebellar artery (PICA) has not been previously reported in the literature. We report six such cases and analyze their clinical characteristics and outcomes from three different treatment strategies. Material and Methods: We reviewed six patients with a diagnosis of distal PICA aneurysm. The following data were analyzed: age, sex, aneurysm size, Hunt-Hess grade at presentation, angiographic characteristics, and clinical treatment outcome determined by Glascow outcome scores (GOS). Treatments performed included clipping and wrapping, sacrificing the parent arteries of the ...
This large multicenter study of flow-diversion therapy demonstrated a neurologic morbidity and mortality rate of 8.4%. Most adverse events were ischemic strokes from thromboembolic complications and were substantially more common in large, anterior circulation aneurysms and posterior circulation aneurysms compared with small, anterior circulation aneurysms. Spontaneous aneurysm rupture was rare, occurring in 0.6% of patients, with 3/5 events occurring within giant aneurysms. Intraparenchymal hemorrhage, unrelated to rupture of the target aneurysm but resulting in major neurologic deficit, was noted in 2.4% of patients. These results are important because they provide clarity regarding the previously noted severe and unexpected adverse events associated with flow-diversion therapy in a real-world setting. Our data suggest strongly that spontaneous aneurysm rupture is not of clinical concern in non-giant aneurysms. Parenchymal hemorrhage remains of concern, especially because its etiology is ...
Methods-We performed a case-control study with 250 patients with an aneurysmal subarachnoid hemorrhage and 206 patients with an unruptured intracranial aneurysm. All patients with an aneurysmal subarachnoid hemorrhage and patients with a unruptured intracranial aneurysm were asked to fill in a structured questionnaire about their lifestyle and medical history. For patients with an unruptured intracranial aneurysm, we also collected data on the indication for imaging. With logistic regression analysis, we identified independent risk factors for aneurysmal rupture.. ...
Endovascular treatment of intracranial aneurysms with detachable coils has been widely used since the introduction of GDCs in 1991 and has been proven to be effective in preventing rebleeding after aneurysmal rupture. The clinical and angiographic results of endovascular coil occlusion of intracranial aneurysms are positive, with an initial and final overall complete occlusion rate of 35.9%-76.8% and 38.3%- 87.8%. In the mid- and long-term, however, aneurysm recanalization may occur in as many as one-third of cases.. The natural history of aneurysm recurrence after coil treatment is often benign, but bleeding from incompletely coiled aneurysms is a well-documented threat, moreover, the degree of aneurysm occlusion after treatment was strongly associated with risk of rerupture. Even if 100% occlusion of the aneurysms after the initial treatment was obtained on immediate postembolization angiography, there was still a relatively high recanalization rate (26.4%) on long-term follow-up angiography. ...
TY - JOUR. T1 - Common Data Elements for Unruptured Intracranial Aneurysms and Subarachnoid Hemorrhage Clinical Research. T2 - A National Institute for Neurological Disorders and Stroke and National Library of Medicine Project. AU - the Unruptured Intracranial Aneurysms and SAH CDE Project Investigators. AU - Suarez, Jose I.. AU - Sheikh, Muniza K.. AU - Macdonald, R. Loch. AU - Amin-Hanjani, Sepideh. AU - Brown, Robert D.. AU - de Oliveira Manoel, Airton Leonardo. AU - Derdeyn, Colin P.. AU - Etminan, Nima. AU - Keller, Emanuela. AU - Leroux, Peter D.. AU - Mayer, Stephan A.. AU - Morita, Akio. AU - Rinkel, Gabriel. AU - Rufennacht, Daniel. AU - Stienen, Martin N.. AU - Torner, James. AU - Vergouwen, Mervyn D.I.. AU - Wong, George K.C.. AU - Mayer, Stephan. AU - Bijlenga, Philippe. AU - Ko, Nerissa. AU - McDougall, Cameron G.. AU - Mocco, J.. AU - Murayama, Yuuichi. AU - Werner, Marieke J.H.. AU - Broderick, Joseph. AU - Dhar, Raj. AU - Jauch, Edward C.. AU - Kirkpatrick, Peter J.. AU - Martin, ...
OBJECTIVE: The usefulness of intraoperative microvascular Doppler (IMD) in preventing an incorrect placement of the clip during intracranial aneurysm surgery is described. Such incorrect placement of the clip may cause new bleeding or ischemic accident as a consequence of incomplete exclusion of the aneurysm or stenosis/occlusion of the parent and/or adjacent arteries. METHODS: One hundred thirty patients, harboring 136 aneurysms, were operated on using IMD. IMD study was performed on the aneurysm and adjacent arterial vessels before and after the clip placement. Mechanical arterial spasm was treated by topical sodium nitroprusside (SNP) and its efficacy verified by IMD. RESULTS: In 55 aneurysms (42.3%), IMD was helpful in understanding the microvascular anatomy before clip placement. Complete exclusion resulted in 129 aneurysms (94.9%). In 5 cases (3.7%) in which IMD revealed a persistent blood flow in the aneurysm, the clip was repositioned. In 2 cases (1.4%), we obtained false-negative ...
TY - JOUR. T1 - Adenosine for temporary flow arrest during intracranial aneurysm surgery. T2 - A single-center retrospective review. AU - Bendok, Bernard R.. AU - Gupta, Dhanesh K.. AU - Rahme, Rudy J.. AU - Eddleman, Christopher S.. AU - Adel, Joseph G.. AU - Sherma, Arun K.. AU - Surdell, Daniel L.. AU - Bebawy, John F.. AU - Koht, Antoun. AU - Batjer, H. Hunt. PY - 2011/10/1. Y1 - 2011/10/1. N2 - Background: Clip application for temporary occlusion is not always practical or feasible. Adenosine is an alternative that provides brief periods of flow arrest that can be used to advantage in aneurysm surgery, but little has been published on its utility for this indication. Objective: To report our 2-year consecutive experience with 40 aneurysms in 40 patients for whom we used adenosine to achieve temporary arterial occlusion during aneurysm surgery. Methods: We retrospectively reviewed our clinical database between May 2007 and December 2009. All patients who underwent microsurgical clipping of ...
Patients with symptomatic intracranial aneurysms are frequently found to have additional aneurysms and may develop new aneurysms over time. LOTUS, long-term stability of coiled intracranial aneurysms, is a study in which MRA (3-D time of flight) was performed on patients in a large cohort with previously coiled aneurysms at 5 years follow-up. In 50 of 276 patients (18%), 75 additional aneurysms were found on follow-up MRA. The majority, 89%, of these additional aneurysms were unchanged, whereas only 5 had grown (from 1-3 mm) and only 2 were de novo (both 3 mm). The cumulative 5-year incidence of de novo aneurysm formation was 0.75%. The clinical implication of these findings from the MRA done at 5 years was that only 4 additional aneurysms in 3 patients were treated. The authors conclude that MRA screening of patients with coiled aneurysms within the first 5 years after treatment has a low rate of de novo aneurysm development and growth of additional aneurysms and an even lower rate of treatment ...
TY - JOUR. T1 - Influence of comorbidities on treatment of unruptured intracranial aneurysms in the elderly. AU - ONeill, Anthea H.. AU - Chandra, Ronil V.. AU - Slater, Lee-Anne. AU - Chong, Winston. AU - Xenos, Christopher. AU - Danks, Andrew Robert. AU - Lai, Leon T.. PY - 2019/4/1. Y1 - 2019/4/1. N2 - Current evidence does not conclusively justify conservative management of unruptured intracranial aneurysms (UIA) in the elderly (age ≥ 65 years). To rationalise intervention, the authors investigated the role of age and comorbidity burden on treatment outcomes. A retrospective chart review for consecutive cases of UIAs treated in the elderly between 2007 and 2018 was performed. Preoperative Charlson Comorbidity Index (CCI) and Neurovascular Comorbidities Index (NCI) were calculated. Standard statistical methods with univariate and multiple logistic regression were used. A total of 123 patients (46 surgery, 77 endovascular) with 131 UIAs were treated. The mean age was 70.6 ± 4.1 years, and ...
Intracranial aneurysms are associated with disturbed velocity patterns, and chronic inflammation, but the relevance for these findings are currently unknown. Here, we show that (disturbed) shear stress induced by vortices is a sufficient condition to activate the endothelial NF-kB pathway, possibly through a mechanism of mechanosensor de-activation. We provide evidence for this statement through in-vitro live cell imaging of NF-kB in HUVECs exposed to different flow conditions, stochastic modelling of flow induced NF-kB activation and induction of disturbed flow in mouse carotid arteries. Finally, CFD and immunofluorescence on human intracranial aneurysms showed a correlation similar to the mouse vessels, suggesting that disturbed shear stress may lead to sustained NF-kB activation thereby offering an explanation for the close association between disturbed flow and intracranial aneurysms.
In the setting of a patient with aneurysmal subarachnoid hemorrhage and multiple intracranial aneurysms the hemorrhage pattern is often the indicator ...
The natural history of unruptured cerebral aneurysms has not been clearly defined. Methods From January 2001 through April 2004, we enrolled patients with newly identified, unruptured cerebral aneurysms in Japan. Information on the rupture of aneurysms, deaths, and the results of periodic follow-up examinations were recorded. We included 5720 patients 20 years of age or […]
Between 3.6 and 6% of the population harbour an unruptured intracranial aneurysm. Risk of rupture is related to aneurysm site and size and whether or not the patient has already had a subarachnoid haemorrhage (SAH) from another aneurysm. In ISUIA 2, the rupture rate for anterior circulation aneurysm …
TY - JOUR. T1 - Management of anterior inferior cerebellar artery aneurysms. T2 - Endovascular treatment and clinical outcome. AU - Suh, S. H.. AU - Kim, D. J.. AU - Kim, D. I.. AU - Kim, Byungmoon. AU - Chung, T. S.. AU - Hong, C. K.. AU - Jung, J. Y.. PY - 2011/1/1. Y1 - 2011/1/1. N2 - BACKGROUND AND PURPOSE: AICA aneurysms are rare and a challenge to treat surgically. We present our experience of the angiographic results and the clinical outcomes for 9 AICA aneurysms treated by EVT. MATERIALS AND METHODS: Between 1997 and 2009, EVT was attempted for 9 AICA aneurysms. Six patients presented with SAH, and 3 aneurysms were found incidentally. The location of the aneurysms was the proximal AICA in 7 and the distal AICA in 2. Five aneurysms originated from an AICA-PICA variant. Clinical outcomes and procedural complications were evaluated, and angiography was performed 6, 12, and 24 months after embolization to confirm recanalization of the coiled aneurysm. RESULTS: EVT was technically successful ...
SUZUKI, M.T.M. et al. De novo basilar tip aneurysm: Case report and literature review. Neurocirugía [online]. 2011, vol.22, n.3, pp.251-254. ISSN 1130-1473.. The de novo aneurysms are the formation of new aneurysms in a location previously observed to be normal by a cerebral angiography or direct microsurgical exploration. In this report, we present a review of the theme and describe a case of a ruptured de novo basilar tip aneurysm in a patient previously treated with carotid occlusion for a giant intracavernous aneurysm and microsurgical clipping of contralateral posterior communicating artery aneurysm.. Keywords : Basilar artery; De novo aneurysm; Subarachnoid hemorrhage. ...
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Clinical presentation A middle-aged patient was referred for treatment of a bilobed saccular aneurysm identified on a CT angiogram performed for a subarachnoid hemorrhage which occurred 20 days prior to presentation. A diagnostic angiogram showed a bilobed wide-necked saccular aneurysm at the AICA origin with the AICA arising from the dome of the aneurysm and also supplying the territory of the posterior inferior cerebellar artery. The therapeutic procedure involved trans-aneurysmal cannulation of the AICA with the microcatheter left in situ. Another microcatheter was maneuvered into the larger dome of the aneurysm. A stent was then deployed in the basilar artery, jailing the previous microcatheter in the aneurysm. Helical Guglielmi detachable coils were deployed in the aneurysm resulting in complete occlusion of the aneurysm with preservation of the AICA.. ...
The clinical characteristics of elderly patients with multiple IAs were studied in 481 patients by Inagawa [31]. Patients were divided into two groups: group 1 - 59 years of age or younger and group 2- 60 years of age or older. Of the 481 patients, 136 (28%) had multiple aneurysms. The percentage of patients with multiple aneurysms was 30% for group 1 and 27% for group 2. The rate of multiple aneurysms was significantly less in males than in females (17% versus 31%). Due to the small sample size, no significant difference could be found between the male and female age groups in terms of the number of aneurysms by gender, yet it is important to highlight that there were no male patients reported in that series with 5 aneurysms or more. The only patients in this series reported to have 5 aneurysms or more were females; one patient in group 1 with 5 aneurysms and one with 6 aneurysms, and a single female patient with more than 5 aneurysms in group 2. Comparable findings were reported by Wilson et ...
Brain Aneurysm Treatment Market Information: By Type (Surgery (Surgical Clipping, Endovascular Coiling), Medication (Antacid, Stool Softener)), Condition (Unruptured Aneurysm, Ruptured Aneurysm), End User (Hospitals, Clinics) - Global Forecast till 2023. Increasing Government Funding Projected to Accelerate the Global Brain Aneurysm Treatment Market. Brain aneurysm is an abnormal bulge in the blood vessels of the brain that can go on to cause severe health-based issues and possible even death. It causes the inner muscular layer of the blood vessel wall to weaken. After a prolonged period of time, the blood flow within the artery keeps pushing the thin wall portion and eventually ends-up rupturing it. The bleeding caused due to the ruptured brain artery is known as subarachnoid hemorrhage (SAH). The hemorrhage is so severe that it can lead to stroke, coma, or even death. Various factors contribute to its occurrence, including injury or trauma, cigarette smoking, blood infections, and others. ...
Unruptured saccular intracranial aneurysm (sIA) is a relatively common disease (2%-3% prevalence).1 Asymptomatic unruptured sIAs are diagnosed increasingly frequently due to improved availability of magnetic resonance imaging (MRI) scans. Although sIAs may rupture causing devastating hemorrhage with mortality of 30% to 50%,2 most sIAs never rupture.3 The pathobiology of sIA formation and rupture need to be elucidated in…
TY - JOUR. T1 - Distal anterior inferior cerebellar artery aneurysms. T2 - Report of four cases. AU - Zager, Eric L.. AU - Shaver, Ellen G.. AU - Hurst, Robert W.. AU - Flamm, Eugene S.. PY - 2002/9. Y1 - 2002/9. N2 - Aneurysms of the distal anterior inferior cerebellar artery (AICA) are rare; fewer than 100 cases have been reported. The authors detail their experience with four cases and present endovascular as well as microsurgical management options. The medical records and neuroimaging studies obtained in four patients who were treated at a single institution were reviewed. Clinical presentations, neuroimaging and intraoperative findings, and clinical outcomes were analyzed. There were three men and one woman; their mean age was 43 years. Two patients presented with acute subarachnoid hemorrhage (SAH), and two presented with ataxia and vertigo (one with tinnitus, the other with hearing loss). Angiographic studies demonstrated aneurysms of the distal segment of the AICA. In one patient with ...
A brain aneurysm is a uniquely devastating occurrence. An aneurysm happens when the artery walls in the brain thin and become unstable. They often form at branches or forks in the arteries where the structures are weaker. Without proper treatment, an aneurysm can lead to brain oxygen deprivation or death. When physicians want to treat […]
Hemodynamics are considered a risk factor for the initiation, growth and rupture of intracranial aneurysms. In this thesis several aspects of the research of hemodynamics in intracranial aneurysms are discussed. First, I discuss the need to obtain aneurysm hemodynamics in a patient-specific manner, followed by possible clinical routines for obtaining such information. Second, the strengths and limitations of presented studies and the underlying technology are discussed. Third, the main outcome of the comparison study in chapter 10 is absence of additional value of aneurysm hemodynamics for characterization of ruptured versus unruptured aneurysm. This outcome raises questions whether there still is a future for hemodynamics in rupture risk prediction, and whether additional studies are still required to determine its definitive role for this purpose ...
Background Antiplatelet agents are required to prevent thromboembolic complications from recently deployed intracranial stents, yet they carry a risk of bleeding complications that may be serious in patients with recent subarachnoid hemorrhage.. Method Consecutive patients at a single institution who had ruptured intracranial saccular aneurysms treated with stent assisted coiling were retrospectively reviewed. Our primary outcomes were ischemic stroke related to the stent and bleeding complications possibly related to antithrombotic therapy. Secondary outcomes included 3 month follow-up National Institute of Health Stroke Scale (NIHSS) scores and modified Rankin Scale (mRS) scores.. Results 44 aneurysms in 42 patients were treated. Seven patients experienced ischemic strokes during their hospitalization. Five ischemic strokes were secondary to vasospasm; one was definitely related to thrombus formation within the stent and one was possibly related to the stent. Two patients had asymptomatic ...
SUMMARY: Giant intracranial aneurysms are rare vascular pathologies associated with high morbidity and mortality. The purpose of this in vivo study was to assess giant intracranial aneurysms and their wall microstructure by 7T MR imaging, previously only visualized in histopathologic examinations. Seven giant intracranial aneurysms were evaluated, and 2 aneurysms were available for histopathologic examination. Six of 7 (85.7%) showed intraluminal thrombus of various sizes. Aneurysm walls were depicted as hypointense in TOF-MRA and SWI sequences with excellent contrast ratios to adjacent brain parenchyma (range, 0.01-0.60 and 0.58-0.96, respectively). The triple-layered microstructure of the aneurysm walls was visualized in all aneurysms in TOF-MRA and SWI. This could be related to iron deposition in the wall, similar to the findings in 2 available histopathologic specimens. In vivo 7T TOF-MRA and SWI can delineate the aneurysm wall and the triple-layered wall microstructure in giant intracranial ...
Four patients with giant intracranial aneurysms, which measured over 2.5 cm in diameter, were treated by ligation of the proximal parent artery. The location of the aneurysms were intracavernous in two patients, paraophthalmic in one patient, and ver
OBJECT: Endovascular treatment of very small aneurysms poses a significant technical challenge for endovascular therapists. The authors review their experience with a series of patients who had intracranial aneurysms smaller than 3 mm in diameter. METHODS: Between 1995 and 2006, 97 very small aneurysms (defined for purposes of this study as | 3 mm in diameter) were diagnosed in 94 patients who were subsequently referred for endovascular treatment. All patients presented after subarachnoid hemorrhage, which was attributed to the very small aneurysms in 85 patients. The authors reviewed the endovascular treatment, the clinical and angiographic results of the embolization, and the complications. RESULTS: Five (5.2%) of the 97 endovascular procedures failed, and these patients underwent craniotomy and clip ligation. Of the 92 aneurysms successfully treated by coil embolization, 64 (69.6%) were completely occluded and 28 (30.4%) showed minor residual filling or neck remnants on the immediate postembolization
Results of a study in the Oct. 26 issue of The Lancet show that researchers -- including a member of a University of Iowa Health Care team -- have determined that a new approach to treating ruptured aneurysms in the brain is superior to surgery.. Researchers at 44 medical centers in Australia, Europe and North America participated in the International Subarachnoid Aneurysm Trial (ISAT). The studys investigators ended the trial early because the early results definitively showed that the new technique achieved better outcomes for patients than traditional surgery.. A brain aneurysm is an abnormal bulging outward of the wall of an artery. The defect is most common among people between ages 35 and 60. Brain aneurysms can cause a stroke when they rupture and blood flows into the brain or the space closely surrounding the brain. The traditional treatment for a ruptured brain aneurysm was surgery. Neurosurgeons placed metal clips across the neck of the aneurysm in an effort to stop arterial blood ...
Background To compare the effects of endovascular coiling and neurosurgical clipping in patients with unruptured intracranial aneurysm.
Computed Tomography Angiography (CTA) plays an essential role in the diagnosis, treatment evaluation, and monitoring of cerebral aneurysms. Segmentation of CTA medical images of giant intracranial aneurysms (GIA) provides quantitative measurements of
Incidental detection of unruptured intracranial aneurysms (UIA) has increased in the recent years. There is a need in the clinical community to identify those that are prone to rupture and would require preventive treatment. Hemodynamics in cerebral blood vessels plays a key role in the lifetime cycle of intracranial aneurysms (IA). Understanding their initiation, growth, and rupture or stabilization may identify those hemodynamic features that lead to aneurysm instability and rupture. Modeling hemodynamics using computational fluid dynamics (CFD) could aid in understanding the processes in the development of IA. The neurosurgical approach during operation of IA allows direct visualization of the aneurysm sac and its sampling in many cases. Detailed analysis of the quality of the aneurysm wall under the microscope, together with histological assessment of the aneurysm wall and CFD modeling, can help in building complex knowledge on the relationship between the biology of the wall and hemodynamics.
110 Francis St. Boston, MA 02215 P 617-632-9940. An aneurysm is an outward bulging, likened to a bubble or balloon, caused by a localized, abnormal, weak spot on a blood vessel wall. A ruptured brain aneurysm is a medical emergency and the clinical team will move quickly. The OHSU Brain Institute is a national leader in diagnosing and treating brain aneurysms. It involves opening the skull by removing a small piece of bone to have open access to locate the aneurysm. An aneurysm in the brain is a weak area in an artery in the brain that bulges out and fills with blood. The Neurological Institute is a leader in treating and researching the most complex neurological disorders and advancing innovations in neurology. An aneurysm in the brain is a weak area in an artery in the brain that bulges out and fills with blood. The neurosurgeon removes a section of your skull to access the aneurysm and locates the blood vessel that feeds the aneurysm. Some unruptured aneurysms need to be surgically repaired, ...
TY - JOUR. T1 - Risk factors for hemorrhagic complications following pipeline embolization device treatment of intracranial aneurysms. T2 - Results from the international retrospective study of the pipeline embolization device. AU - Brinjikji, W.. AU - Lanzino, G.. AU - Cloft, H. J.. AU - Siddiqui, A. H.. AU - Kallmes, D. F.. PY - 2015/12. Y1 - 2015/12. N2 - BACKGROUND AND PURPOSE: Spontaneous intraparenchymal hemorrhage is a dreaded complication of unknown etiology following flow-diversion treatment. Using the International Retrospective Study of the Pipeline Embolization Device registry, we studied demographic, aneurysm, and procedural characteristics associated with intraparenchymal hemorrhage following Pipeline Embolization Device treatment. MATERIALS AND METHODS: Weidentified patients in the International Retrospective Study of the Pipeline Embolization Device registry with intraparenchymal hemorrhage unrelated to index aneurysm rupture post-Pipeline Embolization Device treatment. The rate ...
The Pipeline embolization device is a breakthrough and life-saving endovascular treatment for large or giant wide-neck brain aneurysms, said Joe Woody, president, Vascular Therapies, Covidien. Pipeline now offers hope for those patients who have had no other options for treating this often debilitating and even fatal medical condition.. The Pipeline embolization device PMA application was based on the results of the PUFS (Pipeline for uncoilable or failed aneurysms) clinical trial, a single-arm study of large and giant, wide-neck or fusiform aneurysms that included safety and efficacy data on 108 patients.. Brain aneurysms are a silent killer because most show no symptoms over time, said Christine Buckley, executive Director, The Brain Aneurysm Foundation. The Pipeline embolization device now provides patients with a safe and effective treatment of large or giant, wide-neck aneurysms, which remained an unmet clinical need until now.. The Pipeline embolization device has received CE mark ...
Y-configured double stent technique is useful for coil embolization of a bifurcation wide neck aneurysm while preserving the patency of the two important vessels. However, if the important vessels emanating directly from the aneurysm comprised four vessels, two vessels not deployed, Y-stents might not be preserved with the Y-stent technique by itself. We report a case treated with Y-configured double stent-assisted coil embolization with a double microcatheter technique for complex basilar bifurcation aneurysm. A 78-year-old woman presented with a subarachnoid hemorrhage (SAH) of poor grade. CT-angiography showed a wide neck and shallow aneurysm of complex basilar bifurcation involving both posterior cerebral arteries (PCAs) and superior cerebellar arteries (SCAs). In the chronic stage of SAH, Y-configured double stent-assisted coil embolization with a double microcatheter technique was performed. After Y-stent (two Enterprise) deployment from both the PCAs to the basilar artery, coil ...
Pompe disease is a rare hereditary metabolic disorder caused by α-glucosidase (GAA) deficiency. The late-onset form of the disease (LOPD) is considered a multisystemic disorder which could involve vascular system with cerebrovascular abnormalities such as intracranial aneurysms or dolichoectasia. Intracranial aneurysm rupture may represent a life-threatening emergency. A possible treatment of unruptured intracranial aneurysms (UIAs) should consider both aneurysm-related (aneurysmal size, shape, localization, numbers and hemodynamic factors) and patient-related risk factors (patients age and sex, hypertension, smoke exposure). Moreover, UIAs management of LOPD patients needs also to take into account the altered blood vessels integrity and elasticity, whose consistency is likely weakened by the deficient GAA activity as a further potential risk factor. We herein present our approach for of UIAs management in three patients with LOPD. Among them, only one patient with a left saccular UIA of the ...
TY - JOUR. T1 - Association of meningioma and intracranial aneurysm. T2 - Report of five cases and review of literature. AU - Javalkar, Vijayakumar. AU - Guthikonda, Bharat. AU - Vannemreddy, Prasad. AU - Nanda, Anil. PY - 2009/11/1. Y1 - 2009/11/1. N2 - Meningiomas associated with intracranial aneurysms are very rare. The co-existence of both lesions is not only a diagnostic challenge but also has important therapeutic implications. We analyzed our experience of five such patients, the second largest group in the literature. All the lesions were successfully managed surgically. All the patients were female. The location of the meningioma was clinoidal (2), planum sphenoidale (1), petroclival (1) and pterional (1). Three patients had posterior communicating (PCOM) artery aneurysm associated with meningioma. The other aneurysms were internal carotid artery (ICA) and anterior communicating artery (ACOM). One patient with pterional meningioma had an anomalous meningeal artery arising from the right ...
Baptist Medical Center Jacksonville provides new treatment for ruptured and unruptured brain aneurysms. By Cindy Hamilton. Baptist Medical Center Jacksonville is part of an international trial evaluating a new treatment for both ruptured and unruptured brain aneurysms.. The worldwide study, WEB Intrasaccular Therapy Study (WEB-IT), is approved to enroll 139 patients at up to 25 sites in the U.S., Canada, and Europe and will evaluate the WEB for the treatment of brain aneurysms. Baptist Medical Center Jacksonville had the first cases in the state today performed by Ricardo Hanel, MD, Phd, and neurovascular surgeon with Lyerly Neurosurgery. Baptist Medical Center Jacksonville is the second site in the U.S. where the procedure has been conducted. Visiting physicians also observed.. The WEB Aneurysm Embolization System consists of a dense mesh constructed from a large number of extremely fine wires that is placed into an aneurysm through a catheter by way of the femoral artery. The WEB reduces and ...
We are very pleased with the exceptional results from this landmark trial. It continues to validate findings from previous multicentre and single-centre trials, which is that the HydroCoil system provides excellent results in reducing aneurysm recurrence and retreatment in a wide range of cerebral aneurysms as compared to bare platinum coils, said Richard Cappetta, president and CEO, MicroVention-Terumo.. Procedural safety and efficacy results for HELPS, previously published in 2008, found that the. HydroCoil system can be safely used in a wide spectrum of aneurysms with a risk profile equivalent to thatof bare platinum coils.. Since the HELPS patient enrolment was completed in February 2007, MicroVention-Terumo has continued to innovate the HydroCoil line of coils, including the HydroSoft finishing coil for filling small spaces that provides hydrogel at the neck of the aneurysm, and the HydroFrame framing coil that provides optimal framing of the aneurysm with the clinical benefits of ...
TY - JOUR. T1 - Intravenous abciximab for parent vessel thrombus during basilar apex aneurysm coil embolization. T2 - Case report and literature review. AU - Bendok, Bernard R.. AU - Padalino, David J.. AU - Levy, Elad I.. AU - Qureshi, Adnan I.. AU - Guterman, Lee R.. AU - Hopkins, L. Nelson. PY - 2004/10. Y1 - 2004/10. N2 - Background Parent vessel thrombus formation is a serious complication of intracranial aneurysm embolization. The management of this issue is controversial. Abciximab, a potent platelet inhibitor, has been shown to have thrombolytic effects during coronary interventions. A small number of cases have demonstrated its potential application in neuroendovascular procedures. We review the literature on the management of parent vessel thrombosis during aneurysm coil embolization and report our successful experience with the use of IV abciximab to treat parent vessel thrombus formation related to coil embolization of a basilar apex aneurysm. Case description A 45-year-old man ...
TY - JOUR. T1 - External Validation of the ELAPSS Score for Prediction of Unruptured Intracranial Aneurysm Growth Risk. AU - Kammen, Mayte Sánchez van. AU - Greving, Jacoba P. AU - Kuroda, Satoshi. AU - Kashiwazaki, Daina. AU - Morita, Akio. AU - Shiokawa, Yoshiaki. AU - Kimura, Toshikazu. AU - Cognard, Christophe. AU - Januel, Anne C. AU - Lindgren, Antti. AU - Koivisto, Timo. AU - Jääskeläinen, Juha E. AU - Ronkainen, Antti. AU - Pyysalo, Liisa. AU - Öhman, Juha. AU - Rahi, Melissa. AU - Kuhmonen, Johanna. AU - Rinne, Jaakko. AU - Leemans, Eva L. AU - Majoie, Charles B. AU - Vandertop, W Peter. AU - Verbaan, Dagmar. AU - Roos, Yvo B W E M. AU - Berg, René van den. AU - Boogaarts, Hieronymus D. AU - Moudrous, Walid. AU - Wijngaard, Ido R van den. AU - Hove, Laura Ten. AU - Teo, Mario. AU - George, Edward J St. AU - Hackenberg, Katharina A M. AU - Abdulazim, Amr. AU - Etminan, Nima. AU - Rinkel, Gabriël J E. AU - Vergouwen, Mervyn D I. PY - 2019/9/1. Y1 - 2019/9/1. N2 - Background and ...
For 27 years Deidre Buckley, RN, NP, of the Massachusetts General Hospital Fireman Vascular Centers Brain Aneurysm and Arteriovenous Malformations Program has made it her life mission to help patients like the 34-year-old mother of four who was diagnosed with a brain aneurysm in April.. By the end of the visit, she realized she was going to get through, says Buckley.. For this reason, the Boston Globe recently recognized Buckleys outstanding work in its honorary feature Salute to Nurses. Selected from nurses nominated from across New England, including 23 from Mass General, Buckley stands out as continually going above and beyond the call of duty.. Its something so unique, that you are able to give to others on a daily basis, sometimes without even knowing it, says Buckley.. Using education as a clinical tool In recent years, tremendous progress has been made in treating brain aneurysms. Both neurosurgical and minimally invasive endovascular procedures, such as coiling and stenting, ...
TY - JOUR. T1 - Arterial stenosis after coil migration in embolization of an aneurysm. AU - Meguro, Toshinari. AU - Sasaki, Tatsuya. AU - Haruma, Jun. AU - Tanabe, Tomoyuki. AU - Muraoka, Kenichiro. AU - Terada, Kinya. AU - Hirotsune, Nobuyuki. AU - Nishino, Shigeki. PY - 2010/1/1. Y1 - 2010/1/1. N2 - A case of arterial stenosis after coil migration in intracranial aneurysm embolization is presented. A 51-year-old woman suffered sudden onset of headache and unconsciousness. Computed tomography demonstrated diffuse subarachnoid hemorrhage and cerebral angiography disclosed a right internal carotid artery (ICA) bifurcation aneurysm and a right ICA-anterior choroidal artery aneurysm. The aneurysms were treated by endovascular embolization with Guglielmi detachable coils. During the embolization procedure of the ICA bifurcation aneurysm, a coil strand detached in the sac had migrated into the ICA. We did not retrieve the migrated coil, because the free coil strand was stable in the ICA and did not ...
Theres a new way to treat life-threatening giant aneurysms of the internal carotid artery: Covidiens Pipeline Embolization Device. The flexible 75% coba
TY - JOUR. T1 - Treatment of giant fusiform aneurysms of the basilar trunk with intra-aneurysmal and basilar artery coil embolization. AU - Hassan, Tamer. AU - Ezura, Masayuki. AU - Takahashi, Akira. AU - Debrun, Gerard. AU - Gobin, Y. Pierre. PY - 2004/11. Y1 - 2004/11. N2 - Objective The authors report their experience in endovascular treatment of basilar artery (BA) trunk aneurysms by intra-aneurysmal and BA occlusion. Methods Four patients were referred to our hospital from 1995 until 2002 with variable clinical presentations and radiologic appearances. All the patients were subjected for tolerability to balloon BA occlusion test to verify the collateral supply from the posterior communicating arteries. The patients were treated by intra-aneurysmal embolization together with basilar artery occlusion. Results All the aneurysms were successfully isolated from the circulation. Transient postoperative neurologic deficits were constant findings in all the cases. Outcome was finally good for all ...
Biobusiness grant recipient: Dr. Brenda Ogle, PhD. Grant Period: 2015-2016. Site: Department of Biomedical Engineering , University of Minnesota. Click here to read Ogles Final Report. About six million people in the United States have an unruptured brain aneurysm, according to the Brain Aneurysm Foundation, which means that one in every 50 Americans have a bulging, weak area in the wall of an artery that brings oxygen-rich blood to the brain. The weak areas of the arteries may rupture and hemorrhage, spilling blood instead of delivering it to cells throughout the body. A ruptured artery in the brain causes a stroke. Also, 85 percent of aneurysms go undiagnosed until after they rupture, and one-third of patients with ruptured aneurysm die before they even get to the hospital. Therefore, it is essential to treat aneurysms before they rupture.. Doctors currently treat unruptured intracranial aneurysms (UIA) by blocking the aneurysm to prevent blood from entering the weak ballooned portion of the ...
Patients who present with subarachnoid hemorrhage who have not had a traumatic injury have spontaneous subarachnoid hemorrhage. This is commonly due to an abnormality of the blood vessels within the subarachnoid space that has caused them to rupture and bleed on their own. The most common vascular abnormality leading to subarachnoid hemorrhage is a cerebral aneurysm, or brain aneurysm, but other vascular conditions can also cause subarachnoid hemorrhage. When a patient comes to the hospital with subarachnoid hemorrhage, studies such as CT Angiography or Cerebral Angiography are performed to look for a brain aneurysm or malformation that may have caused the bleeding.. Aneurysmal Subarachnoid Hemorrhage is a medical emergency. It strikes roughly roughly 30,000 people annually in the United States. Many of these people are critically ill. Up to 40% of patients with subarachnoid hemorrhage from a ruptured aneurysm die, and many pass away quickly. Symptoms of SAH include sudden onset severe headache ...
BACKGROUND AND PURPOSE: Utility of the Pipeline Embolization Device extending to the M1 and its clinical and flow consequences at the ICA bifurcation have not been characterized. We analyzed flow modification in cases where a single Pipeline Embolization Device was deployed from the M1 to the distal supraclinoid ICA, covering the A1, for aneurysm treatment. MATERIALS AND METHODS: A1 flow modifications and size regression in postprocedure and follow-up angiography were analyzed. Vessel diameters and ratios of the proximal A1 and M1 segments and the distal ICA were assessed. Relationships between Pipeline Embolization Device nominal diameter and the vessel diameters at landing zones were obtained. Clinical assessments after flow modification were documented. RESULTS: Six of 7 patients demonstrated no change of flow in the anterior cerebral artery/anterior communicating artery complex at immediate postembolization angiography. All patients who underwent follow-up angiography demonstrated size regression of
Looking for online definition of saccular aneurysm in the Medical Dictionary? saccular aneurysm explanation free. What is saccular aneurysm? Meaning of saccular aneurysm medical term. What does saccular aneurysm mean?
Background: Around 30% of people who are admitted to hospital with aneurysmal subarachnoid haemorrhage (SAH) will rebleed in the initial month after the haemorrhage if the aneurysm is not treated. The two most commonly used methods to occlude the aneurysm for prevention of rebleeding are microsurgical clipping of the neck ... read more of the aneurysm and occlusion of the lumen of the aneurysm by means of endovascular coiling. This is an update of a systematic review that was previously published in 2005. Objectives: To compare the effects of endovascular coiling versus neurosurgical clipping in people with aneurysmal SAH on poor outcome, rebleeding, neurological deficit, and treatment complications. Search methods: We searched the Cochrane Stroke Group Trials Register (March 2018). In addition, we searched CENTRAL (2018, Issue 2), MEDLINE (1966 to March 2018), Embase (1980 to March 2018), US National Institutes of Health Ongoing Trials Register (March 2018), and World Health Organization (WHO) ...
Aneurysms that involve the internal carotid artery and posterior communicating artery junction and incorporate a fetal posterior cerebral artery are known as fetal posterior communicating artery aneurysms. We report the outcomes of four patients with fetal posterior communicating artery aneurysms who underwent treatment with the pipeline embolization device with or without adjunctive coil embolization. In our study, all four patients failed to achieve aneurysm occlusion at the last follow-up evaluation. Based on our results, we currently do not recommend the use of the flow diverter for the treatment of fetal posterior communicating artery aneurysms.
TY - JOUR. T1 - The risk of intravenous thrombolysis-induced intracranial hemorrhage in Taiwanese patients with unruptured intracranial aneurysm. AU - Chiu, Wei Ting. AU - Hong, Chien Tai. AU - Chi, Nai Fang. AU - Hu, Chaur Jong. AU - Hu, Han Hwa. AU - Chan, Lung. PY - 2017/6/1. Y1 - 2017/6/1. N2 - Background The presence of an intracranial aneurysm is contraindicated to recombinant tissue plasminogen activator (r-tPA) treatment for acute ischemic stroke. However, it is difficult to exclude asymptomatic intracranial aneurysms by using conventional, noncontrast head computed tomography (CT), which is the only neuroimaging suggested before r-tPA. Recent case reports and series have shown that administering r-tPA to patients with a pre-existing aneurysm does not increase the bleeding risk. However, Asians are known to have a relatively higher bleeding risk, and little evidence is available regarding the risk of using r-tPA on Asian patients with intracranial aneurysms. Methods Medical records from ...
Microsurgical clipping is a technique that cuts off the blood supply to a brain aneurysm to prevent it from rupturing or to control bleeding if a rupture has already occurred.
Contrast-enhanced computed tomography angiography is usually valuable for the evaluation of clipped cerebral aneurysm, but it has side effects of contrast medium. Time-of-flight magnetic resonance angiography (MRA) is a non-invasive and fast method. However, clip-induced artifact limits assessment of the artery in the vicinity of a clip. MRA with ultrashort echo time (TE) reduces metal artifact. We use MAGNETOM Aera 1.5T (SIEMENS, München, Germany) and perform pointwise encoding time reduction with radial acquisition (PETRA)-MRA using ultrashort TE for the assessment of the cerebral aneurysm after clipping. We, herein, presented two representative cases with a clipped aneurysm which could be evaluated by PETRA- MRA. Especially in one of them, the neck remnant was revealed by PETRA-MRA. PETRA-MRA can reduce the time and the invasiveness and may be helpful for the usual follow-up of the clipped aneurysm with the development of MRA technology in the future.. Keywords: Cerebral aneurysm, Clipping, ...
We discuss a case with combined vestibulocochlear and facial neuropathy mimicking a less urgent peripheral vestibular pattern of acute vestibular syndrome (AVS). With initial magnetic resonance imaging read as normal, the patient was treated for vestibular neuropathy until headaches worsened and a diagnosis of subarachnoid hemorrhage was made. On conventional angiography, a ruptured distal right-sided aneurysm of the anterior inferior cerebellar artery was diagnosed and coiled. Whereas acute vestibular loss usually points to a benign peripheral cause of AVS, combined neuropathy of the vestibulocochlear and the facial nerve requires immediate neuroimaging focusing on the cerebellopontine angle. Imaging should be assessed jointly by neuroradiologists and the clinicians in charge to take the clinical context into account. ...
Thrombosis is closely linked to aneurysm evolution. In some cases, the presence of a clot can accelerate the time to aneurysm rupture while in others, it can stabilise the aneurysm and prevent rupture. The few computational models that simulate aneurysm thrombosis have focused on either cerebral aneurysms or on abdominal aortic aneurysms. The aim of these models has been to predict thrombosis outcome following intervention, or to better understand the processes at play during aneurysm thrombus formation. In this work, a joint thrombosis model which can be applied in both cerebral aneurysms and abdominal aortic aneurysms is proposed. It is thought that such an approach will be useful for elucidating clotting features which are common to both pathologies, and highlighting the key differences. This information will be useful for disease management and therapeutic approach. In my previous work, I have developed a computational model of thrombosis in cerebral aneurysms. In this work, I would like to ...
Endovascular coiling is an acceptable treatment of intracranial aneurysms, yet long term follow-ups suggest that endovascular coiling fails to achieve complete aneurysm occlusions particularly in wide-neck and giant aneurysms. Placing of a stentlike device across the aneurysm neck may be sufficient …
Objective: We conducted this study to demonstrate the value of non-invasive three-dimensional CT angiography (3D CTA) in the detection of a cerebral aneurysm. Material and Methods: A helical CT acquisition was obtained using non-ionic contrast media in 50 patients with 1 mm per second table speed, 1 mm collimation, and pitch 1:1. Axial source images were transferred into a workstation console (Advantage windows GE) and CTA was obtained using MIP (Maximum Intensity Projection) reconstruction. Fourteen patients underwent conventional digital subtraction angiography (DSA) after 3D CTA prior to surgery. Results: A total of 39 aneurysms were detected in 50 patients. All patients with an aneurysm were operated and the presence of aneurysms was confirmed. 3D CTA detected 38 of these 39 aneurysms. In 37 aneurysms, the origin of the aneurysm and aneurysm neck was adequately visualized. 3D CTA was found to be 100% specific and 97.2% sensitive in picking up cerebral aneurysms. 3D CTA was 97% specific in ...
TY - JOUR. T1 - Required knowledge for neuroendovascular surgeon (4) basic technique of the coil embolization and parent artery occlusion for cerebral aneurysms. AU - Endo, Hidenori. AU - Matsumoto, Yasushi. AU - Kondo, Ryushi. AU - Suzuki, Ichiro. AU - Kikuchi, Toshio. AU - Tominaga, Teiji. PY - 2012/12. Y1 - 2012/12. KW - Cerebral aneurysm. KW - Coil embolization. KW - Internal trapping. KW - Parent artery occlusion. KW - Vertebral artery dissection. UR - http://www.scopus.com/inward/record.url?scp=84871646131&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=84871646131&partnerID=8YFLogxK. M3 - Article. C2 - 23180749. AN - SCOPUS:84871646131. VL - 40. SP - 1107. EP - 1118. JO - Neurological Surgery. JF - Neurological Surgery. SN - 0301-2603. IS - 12. ER - ...
TY - JOUR. T1 - Medical record and imaging evaluation to identify arterial tortuosity phenotype in populations at risk for intracranial aneurysms.. AU - Diedrich, Karl T.. AU - Roberts, John A.. AU - Schmidt, Richard H.. AU - Albright, Lisa A.Cannon. AU - Yetman, Anji T.. AU - Parker, Dennis L.. PY - 2011. Y1 - 2011. N2 - High arterial tortuosity may signify early arterial pathology which may precede development of intracranial aneurysms. We measured arterial tortuosity of intracranial vessels and reviewed the medical records of three groups of patients: with intracranial aneurysms, without aneurysms but at increased clinical risk, and controls without aneurysms or associated risk factors. There was significant but inconsistent evidence of increased arterial tortuosity in aneurysm cases and high-risk cases across different arteries. Medical records review identified that a subset of aneurysm cases carried a diagnosis of Loeys-Dietz syndrome that is often misdiagnosed as Marfan syndrome. We found ...
Thoracic aortic aneurysms occur in 3 to 4% of persons older than 65 years. The incidence of thoracic aneurysm is approximately 6 to 10 cases per 100,000 person years with the incidence of thoracic aneurysm rupture occurring in 3.5 per 100,000 persons. The average age of diagnosis is 69 years. The prevalence of thoracic aortic aneurysm is up to 4.2% of the general population without hypertension. Most thoracic aortic aneurysms occur in the ascending aorta or the aortic arch. Aneurysm rupture accounts for 60% of deaths. Degenerative aneurysm associated with advanced age most commonly seen. There is no difference between the incidence in males versus females. Arteriosclerosis is the most common cause of thoracic aneurysm involving the descending aorta and aortic arch. It is most common in older individuals with males affected more than females. The etiology of thoracic aortic aneurysm is dependent on the location of the aneurysm. Ascending thoracic aorta aneurysm can be caused by cystic medial ...
A2 anterior cerebral artery aneurysm Also named Proximal pericallosal artery aneurysm. The A2 aneurysms are located between the anterior communicating artery complex and the genu of the corpus callosum on the frontobasal branches. Epidemiology They are very rare with an incidence of 0.2-1% of all intracranial aneurysms . In the
TY - JOUR. T1 - Advanced digital subtraction angiography and MR fusion imaging protocol applied to accurate placement of flow diverter device. AU - Faragò, Giuseppe. AU - Caldiera, Valentina. AU - Tempra, Giovanni. AU - Ciceri, Elisa. PY - 2016/2/1. Y1 - 2016/2/1. N2 - In recent years there has been a progressive increase in interventional neuroradiology procedures, partially due to improvements in devices, but also to the simultaneous development of technologies and radiological images. Cone beam CT (Dyna-CT; Siemens) is a method recently used to obtain pseudo CT images from digital subtraction angiography (DSA) with a flat panel detector. Using dedicated software, it is then possible to merge Dyna-CT images with images from a different source. We report here the usefulness of advanced DSA techniques (Syngo- Dyna CT, three-dimensional DSA iPilot) for the treatment of an intracranial aneurysm with a flow diverter device. Merging MR and Dyna-CT images at the end of the procedure proved to be a ...
In subtraction CT angiography (CTA), a non-contrast CT acquisition is subtracted from a contrast-enhanced CTA acquisition. Subtraction CTA can be applied in the detection, classification, and follow-up of intracranial aneurysms and is advantageous over conventional angiography because of its non-invasive nature, shorter examination time, and lower costs. Recently, an ultra-high-resolution CT scanner has been introduced in clinical practice offering an in-plane spatial resolution of up to 0.234 mm, approaching the resolution as seen during conventional invasive digital subtraction angiography (DSA). The twofold increase in spatial resolution as compared to a conventional CT scanner could improve the evaluation of small vascular structures and, coupled with dedicated post-processing techniques, further reduce metal artifacts. Technical considerations using a state-of-the-art high-resolution subtraction CTA protocol are discussed for application in the follow-up of surgical and endovascular treated
Object. If clip application or coil placement for treatment of intracranial aneurysms is not feasible, the parent vessel can be occluded to induce thrombosis of the aneurysm. The Excimer laser-assisted anastomosis technique allows the construction of a high-flow bypass in patients who cannot tolerate such an occlusion. The authors assessed the complications of this procedure and clinical outcomes after the construction of high-flow bypasses in patients with intracranial aneurysms.. Methods. Data were retrospectively collected on patient and aneurysm characteristics, procedural complications, and functional outcomes in 77 patients in whom a high-flow bypass was constructed. Logistic regression analysis was used to quantify the relationships between patient and aneurysm characteristics on the one hand and outcome measures on the other.. Fifty-one patients harbored a giant aneurysm, 24 patients suffered from a ruptured aneurysm, and 35 patients from an unruptured symptomatic aneurysm. In 22 ...
TY - JOUR. T1 - Peripheral signal void ring in giant vertebral aneurysm. T2 - MR and pathology findings. AU - Hahn, F. J.. AU - Ong, E.. AU - McComb, Rodney D. AU - Leibrock, L.. PY - 1986/1/1. Y1 - 1986/1/1. N2 - Thin, signal void rims have been noted to surround intracerebral hemorrhages and ruptured intracranial aneurysms on magnetic resonance imaging. Proposed mechanisms include hemosiderin deposition in macrophages and high blood flow. The authors describe an example of a thick, signal void ring in a peripheral luminal thrombus of a giant vertebral aneurysm.. AB - Thin, signal void rims have been noted to surround intracerebral hemorrhages and ruptured intracranial aneurysms on magnetic resonance imaging. Proposed mechanisms include hemosiderin deposition in macrophages and high blood flow. The authors describe an example of a thick, signal void ring in a peripheral luminal thrombus of a giant vertebral aneurysm.. KW - Aneurysm, intracranial. KW - Hematoma, cerebral. KW - Magnetic resonance ...
The shape of an aneurysm is described as being fusiform or saccular which helps to identify a true aneurysm. A true aneurysm involves all three layers of the arterial blood vessel wall. The more common fusiform-shaped aneurysm bulges or balloons out on all sides of the aorta. A saccular-shaped aneurysm bulges or balloons out only on one side.. The aorta is under constant pressure from blood being ejected from the heart. With each heartbeat, the walls of the aorta expand and spring back, exerting continual pressure or stress on the already weakened aneurysm wall. Therefore, there is a potential for rupture (bursting) or dissection (separation of the layers of the thoracic aortic wall), which may cause life-threatening hemorrhage (uncontrolled bleeding) and, potentially, death.. Once formed, an aneurysm will gradually increase in size and there will be a progressive weakening of the aneurysm wall. Treatment for a thoracic aneurysm may include surgical repair or removal of the aneurysm to prevent ...
It is important to localize brain lesions and prevent damage to vital structures during operation of brain pathologies. Many techniques have been developed but a more accurate localizing technique is still needed. Neuronavigation is used for this proposes and its utilities are in: biopsy and resection of tumors, endoscopy, skull base surgery and functional neurosurgery. Reports of its use in aneurysmal surgery are scarce.. Schmid-Elsaesser et al. stated that Navigation-CT angiography is useful when performing surgery on unruptured aneurysms, especially middle cerebral artery (MCA) aneurysms. They reported that the deviation of the neck in navigation-CT angiography was less than 2.6 mm and that, with this instrument, MCA aneurysms were approached via minicraniotomy, avoiding detachment of the temporalis muscle. Also they stated that current navigation systems are not precise enough to allow blind aneurysm clipping by placing a real clip on the virtual aneurysm neck (8).. Lee and Bang reported a ...
Over the last several years there have been multiple advances in vascular surgery. One of these is the treatment of mesenteric aneurysms, which are treatable via both endovascular and open means. While the aneurysm itself may cause pain, it is often asymptomatic. Depending on the size and symptoms, an aneurysm may require treatment as if an aneurysm ruptures it can cause a person to quickly bleed to death.If the aneurysm is large, growing, or painful it will need to be treated. Also, splenic aneurysms in young women are or plan on becoming pregnant need to be treated as they have a higher risk of rupture.. A vascular surgeon will perform an aneurysm exclusion or open resection of a mesenteric aneurysm. The first step will be to better characterize the aneurysm and the blood vessels that surround it. Most commonly, patients have had another study such as computed tomography, which demonstrates the aneurysm. Occasionally, one is found on duplex ultrasound. Regardless, optimal visualization of the ...
"Intracranial aneurysm. A nine-year study." Ohio State Medical Journal 1966 Nov;62(11):1168-71.. ... "Surgical risk as related to time of intervention in the repair of intracranial aneurysms." Journal of Neurosurgery 1968 Jan;28( ...
Martin, J. P. (May 1937). "Traumatic Intracranial Aneurysm". Proc R Soc Med. 30 (7): 854-855. doi:10.1177/003591573703000709. ...
International Study of Unruptured Intracranial Aneurysms Investigators) (December 1998). "Unruptured intracranial aneurysms-- ... "Intracranial aneurysms: treatment with bare platinum coils--aneurysm packing, complex coils, and angiographic recurrence". ... Gibbs GF, Huston J, Qian Q, Kubly V, Harris PC, Brown RD, Torres VE (May 2004). "Follow-up of intracranial aneurysms in ... When the aneurysm has been located, platinum coils are deployed that cause a blood clot to form in the aneurysm, obliterating ...
Hitchcock, E., & Gibson, W. T. (2016). A Review of the Genetics of Intracranial Berry Aneurysms and Implications for Genetic ... Because of the variant associated with intracranial aneurysms and its downregulation associated with various albumin levels, ... Genetic study of intracranial aneurysms. Stroke, STROKEAHA-114. Lokman, F. E., Seman, N. A., al-Safi Ismail, A., Azwany Yaacob ... was found across all patients in a study on intracranial aneurysms. However, there was no further research on the gene and its ...
He died of an intracranial aneurysm. His daughter Carlotta Natoli is also an actress. "Addio a Piero Natoli: regista con ...
"Traumatic intracranial aneurysms". "Missile Wounds of the Head and Neck, Volume I". "Missile Wounds of the Head and Neck, ... and predictors of traumatic intracranial aneurysms. In 1999, he co-edited a 2 volume book, entitled Missile Wounds of the Head ...
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Known or suspected intracranial AV malformation or aneurysm. *Known bleeding diathesis (e.g., hemophilia) except for acute ... Recent (within 2 months) intracranial/intraspinal surgery/severe head trauma. *Trauma patients with an increased risk of life- ... During treatment serious bleeding events (e.g., intracranial hemorrhage, any life-threatening bleeding event, any bleeding ...
"Intracranial aneurysms" (PDF). Brain. 41 (1): 50-56. 1918. doi:10.1093/brain/41.1.50. with James McIntosh: "The experimental ...
Rarely, an interrupted aortic arch can be associated with an intracranial aneurysm. Signs of ischemia due to interrupted aortic ... Börcek, Alp Özgün; Egemen, Emrah; Güngör, Günhan; Baykaner, Mustafa Kemali (6 November 2012). "Intracranial aneurysm in ...
"Hemodynamics of Giant Intracranial Aneurysms." In: Awad I and Barrow D, eds, Giant Intracranial Aneurysms. American Association ... "Reporting standards for endovascular repair of saccular intracranial cerebral aneurysms." J Vasc Interv Radiol. 2009 Jul. PMID ... "Guidelines for the management of unruptured intracranial aneurysms. A statement for healthcare professionals from a special ... "Reporting standards for endovascular repair of saccular intracranial cerebral aneurysms." Stroke. 2009 May. PMID 19246711 ...
A flow diverter is an endovascular prosthesis used to treat intracranial aneurysms. It is placed in the aneurysm's parent ... Another situation is fusiform shape or circumferential aneurysms. Prior to flow diverters many intracranial aneurysms went ... Pierot, Laurent (2011). "Flow diverter stents in the treatment of intracranial aneurysms: Where are we?". Journal of ... Flow diverters are treatment for intracranial aneurysms alternative to endosaccular coil embolization (although the techniques ...
In the 1970s Fedor Serbinenko developed a technique for closing intracranial aneurysms with balloons that were released into ... Currie, S; Mankad, K; Goddard, A (Jan 2011). "Endovascular treatment of intracranial aneurysms: review of current practice". ... Group, British Medical Journal Publishing (1963-03-16). "Obliteration of Intracranial Aneurysms by Pilojection". Br Med J. 1 ( ... Fessler, Richard D. (January 2000). "Intracranial Stent Placement to Trap an Extruded Coil During Endovascular Aneurysm ...
Intracranial Aneurysms Results of Surgical Treatment (1960) Fager, CA; Poppen, JL (1960). "Intracranial Aneurysms Results of ...
Chloe tracks them down and threatens to fight with Jana; Jana suffers an intracranial aneurysm and dies on the spot. Kevin and ...
Further studies have implicated the chromosomal region of 1p34.3 in Intracranial Aneurysm and as a negative prognosis sign in ... "Mapping a Mendelian form of intracranial aneurysm to 1p34.3-p36.13". American Journal of Human Genetics. 76 (1): 172-9. doi: ...
April 2001). "Musical hallucinations associated with seizures originating from an intracranial aneurysm". Mayo Clinic ... "Musical hallucinations associated with seizures originating from an intracranial aneurysm", published in the Mayo Clinic ... Miller goes in for her CT scan, which turns up a gigantic aneurysm in her temporal lobe. Dr. Cox breaks the news to Ms. Miller ... through the brain aneurysm), and, despite the singing, the episode fit into the Scrubs continuity. Many noted that the songs ...
Brown died due to an intracranial aneurysm in February 2019. New York City Hardcore:Together, 7″ (1987, Revelation Records) New ...
2010). "Genome-wide association study of intracranial aneurysm identifies three new risk loci". Nat. Genet. 42 (5): 420-425. ... 2008). "Susceptibility loci for intracranial aneurysm in European and Japanese populations". Nat. Genet. 40 (12): 1472-1477. ... of an association of single-nucleotide polymorphism rs1333040 on 9p21 with familial and sporadic intracranial aneurysms in ... association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm ...
Causes of death include respiratory failure, aortic aneurysm, and intracranial hemorrhage. Cutis laxa List of cutaneous ... Quiroga E, Heneghan R (June 2015). "Abdominal aortic aneurysm in a patient with occipital horn syndrome 2". Journal of Vascular ...
"Craniotomy and clipping of intracranial aneurysm in a stereoscopic virtual reality environment". Neurosurgery. 61 (3): 564-568 ...
Yasargil, Mahmut Gazi (1986). Microneurosurgery Tomo II: Clinical Considerations, Surgery of the Intracranial Aneurysms and ... General Operative Techniques and Pathological Considerations of the Intracranial Aneurysms. Thieme. ... performing 7500 intracranial operations in Zurich until his retirement in 1993. In 1994, Yaşargil accepted an appointment as ...
"The association between lunar phase and intracranial aneurysm rupture: Myth or reality? Own data and systematic review". BMC ...
Traumatic aneurysm of the intracranial portion of the internal carotid artery. 1928. "James Leatham Birley". Munk's Roll, ...
"Direct Numerical Simulation of Transitional Flow in a Patient-Specific Intracranial Aneurysm". Journal of Biomechanics. 44 (16 ...
"Closed chest hypothermic circulatory arrest for complex intracranial aneurysms". Ann Thorac Surg. 71 (6): 1900-4. doi:10.1016/ ... Slavin KV, Ausman JI, Charbel FT (1996). "Posterior circulation aneurysms other than basilar tip". In Tindall GT, Cooper PR, ... Frequent topics of these articles have been: surgical aneurysm management brain circulation microanatomy, anastomosis and ... There he expanded his work in microsurgery, cerebrovascular surgery, particularly aneurysms, arteriovenous malformations and by ...
Genomewide linkage in a large Caucasian family maps a new locus for intracranial aneurysms to chromosome 13q. Stroke. 40[suppl ... Association of MMP2 and MMP9 polymorphisms with intracranial aneurysms. J Neurosurg. 105(3):418-23, 2006. Krishna V, Kim DH: ... Sequencing of TGF-beta pathway genes in familial dases of intracranial aneurysm (submitted). Stroke. 40:1604-1611, 2009. Guo DC ... His interest in aneurysms stems from his own family history. Three of Kim's four grandparents died of brain hemorrhages. Kim ...
He begins to struggle for breath and then collapses from an intracranial aneurysm. Later, Graham makes tea for Jan and Sally. ...
In 2014 King suffered an intracranial aneurysm from which he recovered after hospital treatment. In September 2017, along with ... CS1 maint: discouraged parameter (link) 'Si King Sufferred Brain Aneurysm' at Daily Telegraph. Retrieved 6 September 2014 Hairy ...
Gault DT, Renier D, Marchac D, Jones BM (September 1992). "Intracranial pressure and intracranial volume in children with ... wide-set eyes • split uvula or cleft palate • arterial tortuosity • aortic root dilatation • aneurysms 609192 610168 613795 ... Intracranial pressure will rise as a result of continued brain growth within the rigid skull.[16] It appears that in children ... Symptoms of increased intracranial pressure - such as headache and vomiting - should be questioned after.[22][23] An elevation ...
Coronary artery aneurysm. *head / neck *Intracranial aneurysm. *Intracranial berry aneurysm. *Carotid artery dissection ... Aneurysm / dissection /. pseudoaneurysm. *torso: Aortic aneurysm *Abdominal aortic aneurysm. *Thoracic aortic aneurysm ...
... level of consciousness Hypertension Arteriovenous malformation Aneurysm rupture Cerebral amyloid angiopathy Intracranial ... Substantial displacement of brain parenchyma may cause elevation of intracranial pressure (ICP) and potentially fatal ... or if there is an abnormality of a blood vessel known as an aneurysm. Carotid duplex: A carotid duplex is an ultrasound study ... rupture of an aneurysm or arteriovenous malformation (AVM) - arteriopathy (e.g. cerebral amyloid angiopathy, moyamoya) - ...
Coronary artery aneurysm. *head / neck *Intracranial aneurysm. *Intracranial berry aneurysm. *Carotid artery dissection ... Aneurysm / dissection /. pseudoaneurysm. *torso: Aortic aneurysm *Abdominal aortic aneurysm. *Thoracic aortic aneurysm ...
Intra-cranial stenting yang diterapkan pada gejala penyumbatan intracranial arterial stenosis, boleh dikatakan sukses ... CCI paling banyak ditemukan dalam penderita patent foramen ovale baik yang disertai maupun tidak disertai septal aneurysm.[48][ ... "Autopsy prevalence of intracranial atherosclerosis in patients with fatal stroke". Assistance Publique-Hôpitaux de Paris; ... oleh karena disfungsi dan aneurysm bilik kiri jantung. ...
Coronary artery aneurysm. *head / neck *Intracranial aneurysm. *Intracranial berry aneurysm. *Carotid artery dissection ... causing increased intracranial pressure and cerebral edema, with increased risk of intracranial bleeding. ... CT scan depicting intracranial hemorrhage, a possible complication of hypertensive emergency. Patients with spontaneous ... and intracranial bleeding. Cardiovascular system damage can include myocardial ischemia/infarction, acute left ventricular ...
Intracranial bleedingEdit. Main article: Intracranial hemorrhage. Types of intracranial hemorrhage are roughly grouped into ... can result either from trauma or from ruptures of aneurysms or arteriovenous malformations. Blood is seen layering into the ... This is a very dangerous type of injury because the bleed is from a high-pressure system and deadly increases in intracranial ... Types of intracranial hemorrhage include subdural, subarachnoid, extradural, and intraparenchymal hematoma. Craniotomy ...
Coronary artery aneurysm. *head / neck *Intracranial aneurysm. *Intracranial berry aneurysm. *Carotid artery dissection ... Aneurysm / dissection /. pseudoaneurysm. *torso: Aortic aneurysm *Abdominal aortic aneurysm. *Thoracic aortic aneurysm ...
Coronary artery aneurysm. *head / neck *Intracranial aneurysm. *Intracranial berry aneurysm. *Carotid artery dissection ... Dissecting aneurysms of the vertebral artery constitute 4% of all cerebral aneurysms, and are hence a relatively rare but ... Santos-Franco JA, Zenteno M, Lee A (April 2008). "Dissecting aneurysms of the vertebrobasilar system. A comprehensive review on ... or as an aneurysm (area of dilation, 5-13%). The narrowing may be described as "rat's tail" or "string sign".[1] Cerebral ...
Basilar artery aneurysms represent only 3%-5% of all intracranial aneurysms but are the most common aneurysms in the posterior ... Intracranial aneurysm, also known as brain aneurysm, is a cerebrovascular disorder in which weakness in the wall of a cerebral ... Saccular aneurysms[edit]. Saccular aneurysms, also known as berry aneurysms, appear as a round outpouching and are the most ... See also: Aneurysm § Pathophysiology. Aneurysm means an outpouching of a blood vessel wall that is filled with blood. Aneurysms ...
Cerebral aneurysm. *Cerebral arteriosclerosis. *Cerebral atrophy. *Cerebral autosomal dominant arteriopathy with subcortical ...
a b c d e f g h eMedicine Specialties , Neurology , Neurological Emergencies , Intracranial Haemorrhage: Treatment & Medication ... Brain trauma, aneurysms, arteriovenous malformations, brain tumors[1]. Risk factors. High blood pressure, amyloidosis, ... Intracerebral hemorrhage (ICH), also known as cerebral bleed, is a type of intracranial bleed that occurs within the brain ... Acceleration-deceleration trauma,[9][10][11] rupture of an aneurysm or arteriovenous malformation (AVM), and bleeding within a ...
... of suicide or murder and that Ferrie died of a massive cerebral hemorrhage due to a congenital intracranial berry aneurysm that ...
... and the first clipping of an intracranial aneurysm ... The clipping of an aneurysm is performed under microscopic ... Endovascular neurosurgery utilizes endovascular image-guided procedures for the treatment of aneurysms, AVMs, carotid stenosis ... He studied how blood vessels in the brain reacted to changes in intracranial pressure by placing glass windows in the skulls of ... tumors of the meninges and intracranial spaces, secondary metastases to the brain, spine, and nerves, and peripheral nervous ...
Coronary artery aneurysm. *head / neck *Intracranial aneurysm. *Intracranial berry aneurysm. *Carotid artery dissection ... may be required to identify aneurysms of the brain blood vessels, the most common cause of SAH.[10] ... Aneurysm / dissection /. pseudoaneurysm. *torso: Aortic aneurysm *Abdominal aortic aneurysm. *Thoracic aortic aneurysm ...
Coronary artery aneurysm. *head / neck *Intracranial aneurysm. *Intracranial berry aneurysm. *Carotid artery dissection ... Aneurysm / dissection /. pseudoaneurysm. *torso: Aortic aneurysm *Abdominal aortic aneurysm. *Thoracic aortic aneurysm ...
Coronary artery aneurysm. *head / neck *Intracranial aneurysm. *Intracranial berry aneurysm. *Carotid artery dissection ... Other diseases caused by high blood pressure include ischemic heart disease, stroke, peripheral arterial disease, aneurysms and ... Aneurysm / dissection /. pseudoaneurysm. *torso: Aortic aneurysm *Abdominal aortic aneurysm. *Thoracic aortic aneurysm ...
Common causes of focal or localized brain damage are physical trauma (traumatic brain injury, stroke, aneurysm, surgery, other ... Brain tumors can increase intracranial pressure, causing brain damage.. Chemotherapy can cause brain damage to the neural stem ... Vascular disorders of the brain include thrombosis, embolisms, angiomas, aneurysms, and cerebral arteriosclerosis.[25] ...
Coronary artery aneurysm. *head / neck *Intracranial aneurysm. *Intracranial berry aneurysm. *Carotid artery dissection ...
Coronary artery aneurysm. *head / neck *Intracranial aneurysm. *Intracranial berry aneurysm. *Carotid artery dissection ... I71.8) Aortic aneurysm of unspecified site, ruptured. *(I71.9) Aortic aneurysm of unspecified site, without mention of rupture ... I60.6) Subarachnoid haemorrhage from other intracranial arteries. *(I60.7) Subarachnoid haemorrhage from intracranial artery, ... I62) Other nontraumatic intracranial haemorrhage *(I62.0) Subdural haemorrhage (acute)(nontraumatic). *(I62.1) Nontraumatic ...
Wall M (2008). «Idiopathic intracranial hypertension (pseudotumor cerebri)». Curr Neurol Neurosci Rep. 8 (2): 87-93. PMID ... Flanagan CM, Kaesberg JL, Mitchell ES, Ferguson MA, Haigney MC (2008). «Coronary artery aneurysm and thrombosis following ...
Intracranial hemorrhage - bleeding in the skull.. *Cerebral hemorrhage - a type of intracranial hemorrhage, bleeding within the ... Intramural changes - changes arising within the walls of blood vessels (e.g. aneurysms, dissections, AVMs, vasculitides) ... usually from rupture of a berry aneurysm or arteriovenous malformation(AVM). The scope of this article is limited to these ... "18F-positron-emitting/fluorescent labeled erythrocytes allow imaging of internal hemorrhage in a murine intracranial ...
Aneurysm. *Cerebral aneurysm *Intracranial berry aneurysm. *Charcot-Bouchard aneurysm. Other/general. *Cerebral vasculitis ...
... thus exposing the dura mater in order to treat health problems related to intracranial pressure and other diseases. ... damage to the Achilles tendon and a more effective method for applying ligature of the arteries in case of an aneurysm.[54] He ... operative procedure for hydrocephalus was given by Al-Zahrawi who clearly describes the evacuation of superficial intracranial ...
Deaths from intracranial aneurysm. *Guitarists from Chicago. *20th-century American guitarists. *American rock guitarist stubs ... He died on February 13, 1988, from a brain aneurysm. He was survived by his wife and their son.[4] ...
Cerebral aneurysms. *Some forms of hemorrhagic stroke, such as subarachnoid hemorrhages, as well as intraparenchymal र ... including the surgical र endovascular treatment of disorders of the intracranial र extracranial vasculature supplying the brain ...
Daiths frae intracranial aneurysm. *Age controversies. Skauk't categeries: *Airticles wi hCards. *Wikipaedia airticles wi BNE ...
Mount, L.A., Antunes, J.L.: Results of treatment of intracranial aneurysms by wrapping and coating. J. Neurosurg. 42:189-193, ... Antunes, J.L., Correll, J.W.: Cerebral Emboli from intracranial aneurysms. Surg. Neurol. 6:7-10, 1976 ... Antunes, J.L., Valença, A., Ferro, J.M. e Campos, J.: Ruptured saccular aneurysm associated with duplication of the vertebral ...
Basilar artery aneurysms represent only 3%-5% of all intracranial aneurysms but are the most common aneurysms in the posterior ... Intracranial aneurysm, also known as brain aneurysm, is a cerebrovascular disorder in which weakness in the wall of a cerebral ... Saccular aneurysms[edit]. Saccular aneurysms, also known as berry aneurysms, appear as a round outpouching and are the most ... See also: Aneurysm § Pathophysiology. Aneurysm means an outpouching of a blood vessel wall that is filled with blood. Aneurysms ...
... An aneurysm represents a weak spot in the wall of an artery which results in a "focal bulge" or widening ... Currently, there are two methods of treating intracranial aneurysms:. *Brain surgery with placement of a clip around the neck ... Embolization of the aneurysm with placement of platinum GDC coils from inside the blood vessel through a catheter in the groin. ... In the brain, these aneurysms have a 2-4% annual risk of rupture which can result in "subarachnoid hemorrhage", or bleeding in ...
A ruptured intracranial aneurysm causes intracranial bleeding and is considered very dangerous. ... A ruptured intracranial aneurysm causes intracranial bleeding and is considered very dangerous. ...
Temporary parent vessel clip occlusion in aneurysm surgery is not always practical or feasible. Adenosine-induced transient ... Giant intracranial aneurysms: evolution of management in a contemporary surgical series. Neurosurgery. 2011;69:1261-70; ... Meling T.R. (2018) Adenosine-Assisted Clipping of Intracranial Aneurysms. In: Esposito G., Regli L., Kaku Y., Tsukahara T. (eds ... Adenosine-induced flow arrest to facilitate intracranial aneurysm clip ligation does not worsen neurologic outcome. Anesth ...
DX: Intracranial aneurysm coil extending into the right common femoral artery. Procedure: Right common femoral cut down with ... DX: Intracranial aneurysm coil extending into the right common femoral artery. Procedure: Right common femoral cut down with ... Subsequently, the aneurysm coil fiber was then used to wrap and tie down to the external adventitial area of the common femoral ... Subsequently, the aneurysm coil fiber was then used to wrap and tie down to the external adventitial area of the common femoral ...
During the editing of this editorial about intracranial aneurysms in autosomal dominant polycystic kidney disease by Albert C M ... Screening for intracranial aneurysms in ADPKD. BMJ 2009; 339 doi: https://doi.org/10.1136/bmj.b4204 (Published 13 October 2009) ... "New aneurysms . . ." And the second sentence of the fourth paragraph should read: "The only factor that seemed to correlate ... Ong (BMJ 2009;339:b3763, doi:10.1136/bmj.b3763), we mistakenly twice used "ruptures" instead of "aneurysms." The last sentence ...
The International Study of Unruptured Intracranial Aneurysms (ISUIA) indicated a relatively low risk of rupture in small an... ... The management of unruptured intracranial aneurysms is highly controversial. ... Drugs & Diseases , Neurology , Cerebral Aneurysms Q&A What are treatment guidelines for unruptured intracranial aneurysms?. ... The management of unruptured intracranial aneurysms is highly controversial. The International Study of Unruptured Intracranial ...
Basilar artery aneurysms represent only 3-5% of all intracranial aneurysms but are the most common aneurysms in the posterior ... An intracranial aneurysm, also known as a brain aneurysm, is a cerebrovascular disorder in which weakness in the wall of a ... Charcot-Bouchard aneurysms are a common cause of intracranial hemorrhage.[citation needed] A small, unchanging aneurysm will ... Cerebral aneurysms are classified both by size and shape. Small aneurysms have a diameter of less than 15 mm. Larger aneurysms ...
Dissecting aneurysms of the intracranial vertebral artery.. Yamaura A1, Watanabe Y, Saeki N. ... Among 86 patients with aneurysms arising from the vertebral artery or its branches, 24 had dissecting aneurysms. The patients ... After this period, the aneurysm was whitish gray in color and had become firm. Of 36 other cases of vertebral dissecting ... aneurysm reported in the literature, 20 were operated on. The indications for surgery are discussed. ...
Adult polycystic kidney disease and intracranial aneurysms. Br Med J (Clin Res Ed) 1987; 295 :526 ... Adult polycystic kidney disease and intracranial aneurysms.. Br Med J (Clin Res Ed) 1987; 295 doi: https://doi.org/10.1136/bmj. ...
... infected intracranial aneurysm, to include the categories of intracranial bacterial aneurysm, fungal aneurysm, spirochetal ... An infectious intracranial aneurysm (IIA, also called mycotic aneurysm) is a cerebral aneurysm that is caused by infection of ... The terms infectious aneurysm and infective aneurysm are flawed because they imply that the aneurysm itself is the infecting ... aneurysm, infested or amebic aneurysm, viral aneurysm and phytotic aneurysm, according to the specific infecting organism or ...
... growth and rupture of intracranial aneurysms. In this thesis several aspects of the research of hemodynamics in intracranial ... Chapter 9: Hemodynamic differences in intracranial aneurysms before and after rupture. * Chapter 10: Additional value of intra- ... Hemodynamics in intracranial aneurysms. Supervisors. C.B.L.M. Majoie. E.T. van Bavel. ... Chapter 7: Intracranial aneurysm neck size overestimation with 3D rotational angiography: The impact on intra-aneurysmal ...
Intracranial Aneurysms and Cognitive Function. Brief Summary The prevalence rate of intracranial aneurysms in the adult ... Intracranial Aneurysms and Cognitive Function. The recruitment status of this study is unknown. The completion date has passed ... Sandell T, Isaksen J, Bajic R, Ingebrigtsen T. [Treatment of intracranial aneurysms]. Tidsskr Nor Laegeforen. 2005 Aug 25;125( ... Patients with un-ruptured aneurysms in the anterior communicating artery and the middle cerebral artery.A subgroup of patients ...
Mortality rates after treatment of unruptured intracranial aneurysms have substantially decreased in the past decade, according ... Tags: Aneurysm, Brain, Brain Aneurysm, Brain Surgery, Education, Hospital, Intracranial Aneurysm, Medicine, Mortality, Neck, ... Treatment of unruptured intracranial aneurysms substantially reduces mortality rates. *Download PDF Copy ... The study, Trends in Mortality and Morbidity after Treatment of Unruptured Intracranial Aneurysm in the United States, 2006- ...
... By Wayne Forrest, AuntMinnie.com contributing writer. December 3, 2013 -- ... Ruptured intracranial aneurysms are considered the main cause of subarachnoid hemorrhage, so detection and assessment of ... 7-tesla TOF MRA allowed for a significantly improved delineation of the intracranial aneurysms." ... Image A shows 1.5-tesla TOF MRA of a 55-year-old patient with an unruptured basilar aneurysm (arrow). Image B is a ...
Surgery remains a viable option at any time for treating aneurysms that have been previously treated by GDC placement. The ... Surgery following endovascular coiling of intracranial aneurysms Surg Neurol. 2000 Nov;54(5):352-60. doi: 10.1016/s0090-3019(00 ... Background: Surgery for intracranial aneurysms that have been treated by endovascular coiling is a new challenge for ... In two cases it was possible to place a clip across the neck of the aneurysm without removing the coils, as the coils no longer ...
Recurrence of intracranial aneurysms in autosomal-dominant polycystic kidney disease.. Belz MM1, Fick-Brosnahan GM, Hughes RL, ... The natural history of intracranial aneurysms (ICAs) in individuals with autosomal-dominant polycystic kidney disease (ADPKD) ...
Aneurysm. Intracranial Aneurysm. Vascular Diseases. Cardiovascular Diseases. Intracranial Arterial Diseases. Cerebrovascular ... The prevalence rate of intracranial aneurysms in the adult population is close to 5%. Rupture risk of such aneurysms causing ... Intracranial Aneurysms and Cognitive Function. The safety and scientific validity of this study is the responsibility of the ... Sandell T, Isaksen J, Bajic R, Ingebrigtsen T. [Treatment of intracranial aneurysms]. Tidsskr Nor Laegeforen. 2005 Aug 25;125( ...
... of systematic reviews performed to investigate factors that might influence the risk of rupture of an intracranial aneurysm. It ... Systematic review of reviews of risk factors for intracranial aneurysms Neuroradiology. 2008 Aug;50(8):653-64. doi: 10.1007/ ... The annual incidence of subarachnoid haemorrhage resulting from the rupture of intracranial aneurysms is estimated to be nine ... posterior circulation aneurysms, larger aneurysms, previous symptoms, "non-white" ethnicity, hypertension, low body mass index ...
Hemodynamics in cerebral blood vessels plays a key role in the lifetime cycle of intracranial aneurysms (IA). Understanding ... In this chapter we summarize current knowledge on CFD and intracranial aneurysms. ... The neurosurgical approach during operation of IA allows direct visualization of the aneurysm sac and its sampling in many ... Detailed analysis of the quality of the aneurysm wall under the microscope, together with histological assessment of the ...
Chapter 4: Type III collagen and intracranial aneurysms.. * Chapter 5: Some patients with intracranial aneurysms have a reduced ... The pathogenesis of saccular intracranial aneurysms.. * Chapter 2: Is Marfan syndrome associated with symptomatic intracranial ... Chapter 6: Type III collagen deficiency in saccular intracranial aneurysms; defect in gene regulation or collagen processing?. ... Chapter 3: Prevalence of symptomatic intracranial aneurysms and ischaemic strokes in Pseudoxanthoma Elasticum.. ...
report deals with 38 unruptured intracranial aneurysms ( Table 1 ). These aneurysms were found in 29 patients from a ... including eight patients with unruptured intracranial aneurysms). Intracranial spasm was also noted in association with active ... 29 who studied the natural history of unruptured intracranial aneurysms in 65 patients followed for an average of 8.2 years. ... Enlargement of an intracranial aneurysm in the eighth decade of life Case report ...
Josephs Hospital extends their aneurysm speciality to intracranial aneurysms, which can cause tremendous pressure inside the ... Who is susceptible to an intracranial aneurysm?. Between 1.5 and 8 percent of the population may suffer from intracranial ... are at increased risk for intracranial aneurysms.. How often do aneurysms rupture?. No one knows for sure. However, several ... What causes an intracranial aneurysm?. There is so single cause. Some people suffer from congenital defects that weaken the ...
Purpose Patients over the age of 80 years when diagnosed with an unruptured intracranial aneurysm (UIA) pose unique decision- ... Unruptured Intracranial Aneurysm 80 years Natural history Endovascular This article is part of the Topical Collection on ... Cai Y, Spelle L, Wang H, Piotin M, Mounayer C, Vanzin JR, Moret J (2005) Endovascular treatment of intracranial aneurysms in ... Hwang SK, Hwang G, Oh CW, Jin SC, Park H, Bang JS, Kwon OK (2011) Endovascular treatment for unruptured intracranial aneurysms ...
"International Study of Unruptured Intracranial Aneurysms Investigators. Unruptured intracranial aneurysms: natural history, ... reported that 3D TOF MRA at 3 T had more clear depiction of intracranial aneurysms compared to 1.5 T, even though all aneurysms ... and intracranial aneurysms. It is applicable to cooperative patients, and it can detect even small-sized aneurysms (,3 mm), ... "A diagnostic pitfall for intracranial aneurysms in time-of-flight MR angiography: small intracranial lipomas," AJR: American ...
The effects of Reynolds and Womersley numbers on the hemodynamics of two simplified intracranial aneurysms (IAs), that is, ... "Influence of hemodynamic factors on rupture of intracranial aneurysms: patient-specific 3D mirror aneurysms model computational ... H. Asgharzadeh, I. Borazjani, J. Xiang, and H. Meng, "Vortex generation in two intracranial aneurysms," in Proceedings of the ... The rupture of intracranial aneurysms (IAs) is highly associated with mortality and morbidity [1]. Hemodynamics has a ...
Flow Diversion for Intracranial Aneurysms. A Review. Pietro I. DUrso, Giuseppe Lanzino, Harry J. Cloft, David F. Kallmes ... The introduction of flow diverters for treatment of intracranial aneurysms represents a major paradigm shift in the treatment ... Flow diverters are designed to induce disruption of flow near the aneurysm neck while preserving flow into parent vessel and ... The theoretical hallmark of flow diverters is the treatment of the diseased segment harboring the aneurysm instead of treating ...
The Electroencephalogram in Intracranial Aneurysms. E. Roseman, B. M. Bloor, Richard P. Schmidt ...
International Study of Unruptured Intracranial Aneurysms Investigators. Unruptured intracranial aneurysms: natural history, ... fusiform aneurysms, large neck aneurysms, aneurysms with unfavorable size relationship between aneurysm dome, neck, and parent ... including large and giant aneurysms, wide-neck aneurysms, fusiform aneurysms, and recanalized aneurysms after previous coiling ... Stent-assisted coiling of intracranial aneurysms: clinical and angiographic results in 216 consecutive aneurysms. Stroke. 2010; ...
... is releasing its CODMAN ENTERPRISE 2 intracranial vascular stent. The device is intended to treat ... CODMAN ENTERPRISE 2 Intracranial Aneurysm Stent Released in U.S.. February 17th, 2016 Editors Neurology, Neurosurgery, ... The device is intended to treat wide-necked intracranial aneurysms in conjunction with endovascular coils. It helps in ... Pipeline Flex Embolization Device Approved for Small and Medium Brain Aneurysms. Siemens Healthineers Powerful MAGNETOM Lumina ...
  • Diagram of cerebral aneurysm. (wikipedia.org)
  • The risk of rupture from a cerebral aneurysm varies according to the size of an aneurysm, with the risk rising as the aneurysm size increases. (wikipedia.org)
  • Young WL, Lawton MT, Gupta DK, Hashimoto T. Anesthetic management of deep hypothermic circulatory arrest for cerebral aneurysm clipping. (springer.com)
  • Saccular aneurysms, also known as berry aneurysms, appear as a round outpouching and are the most common form of cerebral aneurysm. (wikipedia.org)
  • Brooks M. Serial Screening for Cerebral Aneurysm Fruitful. (medscape.com)
  • An infectious intracranial aneurysm (IIA, also called mycotic aneurysm) is a cerebral aneurysm that is caused by infection of the cerebral arterial wall. (wikipedia.org)
  • Comparative analysis of unruptured cerebral aneurysm treatment outcomes and complications with the classic versus flex pipeline embolization devices and phenom versus marksman microcatheter delivery system: the role of microcatheter choice on complication rate. (fda.gov)
  • Intracranial or cerebral aneurysm is characterized by a balloon-like swelling in the blood vessel inside the brain, which generally appears in the lower region of the brain. (prnewswire.co.uk)
  • Background: A subarachnoid hemorrhage (SAH) due to the rupture of a cerebral aneurysm (CA) is a devastating event associated with high rates of mortality. (ebscohost.com)
  • A study of 8 unoperated cases of anterior cerebral aneurysm. (thejns.org)
  • By understanding the mechanisms of cerebral aneurysm formation, we might devise intervention to prevent its rupture. (cns.org)
  • By the conclusion of this session, participants should be able to: 1) describe hyperhomocysteinemia as a possible factor in cerebral aneurysm development, and 2) discuss possible mechanisms by which homocysteinemia exsert vascular injury. (cns.org)
  • Taki W, Sakai N, Nakahara I, Osaka N, Koshiji T, Matsuda K, Enoki Y, Kikuchi H. Circulatory arrest with profound hypothermia during the surgical treatment of large internal carotid artery aneurysm-case report. (springer.com)
  • Aneurysms were located in the anterior circulation (n = 31), with six arising from the anterior communicating artery, one from the pericallosal artery, four from the middle cerebral artery, and 20 from the internal carotid artery. (ajnr.org)
  • af Björkesten G. Arterial aneurysms of the internal carotid artery and its bifurcation. (thejns.org)
  • Procedure-related complications occurred in 3 of 37 patients (8.1%), including 1 case of intraprocedure aneurysm rupture who died from cerebral herniation caused by severe postoperative cerebral ischemia during the hospital stay, and the other 2 complications were acute in-stent thrombosis, and occlusion of parent artery caused by falling-off internal carotid artery plaque, respectively. (bioportfolio.com)
  • Enterprise stent in recanalizing non-acute atherosclerotic intracranial internal carotid artery occlusion. (bioportfolio.com)
  • The locations of the aneurysms were the internal carotid artery ( n = 12) and basilar artery ( n = 4). (scialert.net)
  • Stenting and secondary coiling of intracranial internal carotid artery aneurysm: technical case report. (springer.com)
  • The mean angle between the arch and its branches, between the internal carotid artery and the anterior cerebral artery, and between the anterior communicating artery and the aneurysm was more acute in group II compared with group I. Spearman's correlation suggested that as the angle at different vessel levels decreased, duration, attempt, and complications increased, and vice versa. (sigmaaldrich.com)
  • The patient's twin sister was called for screening, whereupon digital subtraction angiography revealed a right ophthalmic internal carotid artery aneurysm that was treated conservatively. (hkmj.org)
  • Rebleeding, hydrocephalus (the excessive accumulation of cerebrospinal fluid ), vasospasm (spasm, or narrowing, of the blood vessels), or multiple aneurysms may also occur. (wikipedia.org)
  • In addition, two patients with unruptured intracranial aneurysms underwent surgery, one because of temporal lobe epilepsy and the other patient, who harbored multiple aneurysms, for clipping of an unruptured aneurysm in an elective procedure. (thejns.org)
  • The use of intravenous contrast media is necessary for the identification of blood vessels and provides accurate information regarding the location, the size, and the shape of an aneurysm, as well as the presence of multiple aneurysms. (hindawi.com)
  • Doddasomayajula R, Chung BJ, Mut F, Jimenez CM, Hamzei-Sichani F, Putman CM, Cebral JR. Hemodynamic Characteristics of Ruptured and Unruptured Multiple Aneurysms at Mirror and Ipsilateral Locations. (umassmed.edu)
  • Potential risk factors associated with multiple aneurysms may shed light on the possible cause of aneurysm formation in the first place. (cns.org)
  • 1) In this study, investigators compared patients who underwent microsurgical clipping to see what factors are associated with patients having multiple aneurysms pre-operatively discovered on imaging. (cns.org)
  • Patients with multiple aneurysms present comprised 16.7% (59/353) of the population. (cns.org)
  • We found no difference in patients with multiple aneurysms between gender type (p-value=.20), age (p-value=.26), patients = 50 (p-value=.67), history of hypertension (p-value=.12), tobacco use (p-value=.68), alcohol use (p-value=.13), location (p-value=.28), SAH at presentation (p-value=.87), and outcomes (p-value=.45). (cns.org)
  • almost a third had multiple aneurysms present. (cns.org)
  • By the conclusion of this session, participants should be able to 1) identify risk factors associated with patients having multiple aneurysms. (cns.org)
  • The Familial Intracranial Aneurysm Study is a collaborative research effort of neurologists and neurosurgeons throughout the United States, Canada, Australia and New Zealand to identify possible genes that may increase the risk of stroke, and particularly, the development of aneurysms in the blood vessels of the brain. (clinicaltrials.gov)
  • This study of affected individuals and families, known as the Familial Intracranial Aneurysm (FIA) study, is sponsored by the National Institutes of Health and has involved over 475 families. (clinicaltrials.gov)
  • People who have experienced ruptured aneurysms and want to participate in the Familial Intracranial Aneurysm II study are encouraged to contact Laura Sauerbeck at (513) 558-1742. (uc.edu)
  • The funds, spread over two years, are part of a grant renewal from the National Institutes of Health (NIH) in support of the Familial Intracranial Aneurysm (FIA) II study, a collaborative research effort of investigators examining multiple populations in the United States and elsewhere. (uc.edu)
  • Researchers examined magnetic resonance angiographies (MRA) of 548 subjects from the international Familial Intracranial Aneurysm study with a strong family history of intracranial aneurysm who also had a history of smoking or hypertension but no known intracranial aneurysm. (uc.edu)
  • Discovery sample (DS) 1 consisted of individuals recruited through the Familial Intracranial Aneurysm (FIA) I study, 7 which recruited familial cases appropriate for linkage analysis 8 through an international consortium and applied rigorous inclusion and exclusion criteria. (pubmedcentralcanada.ca)
  • Refer to Holtzman RNN, Pile-Spellman JMD, Brust JCM, Hughes JEO, Dickinson PCT: Surgical Management of Intracranial Aneurysms Caussed by Infection, in: Schmidek HH and Roberts DW(eds): Schmidek & Sweet Operative Neurosurgical Techniques: Indications, Methods, and Results ed.5. (wikipedia.org)
  • Management of intracranial aneurysms has improved significantly during recent years because of major technical advances. (ajnr.org)
  • Background: The ISAT and ISUIA studies, along with the improvement of endovascular treatment (EVT) have strongly influenced the management of intracranial aneurysms (IAs). (ebscohost.com)
  • Botterell E. H. Lougheed W. M. Scott J. W. and Vandewater S. L. Hypothermia, and interruption of carotid, or carotid and vertebral circulation, in the surgical management of intracranial aneurysms. (thejns.org)
  • Presently, endovascular therapy largely supersedes surgical intervention in the management of intracranial aneurysms in the developed world. (bmj.com)
  • The natural history of intracranial aneurysms (ICAs) in individuals with autosomal-dominant polycystic kidney disease (ADPKD) is poorly defined. (nih.gov)
  • This is because of a lack of understanding of the natural history of intracranial aneurysms and the published results regarding procedural complications associated with neurosurgical and endovascular treatments ( 5 - 8 ). (ajnr.org)
  • The document contains discussions about the natural history of intracranial aneurysms, diagnostic evaluation, surgical treatment and screening for unruptured intracranial aneurysms. (aafp.org)
  • Aneurysm of the basilar artery , and the vertebral arteries . (wikipedia.org)
  • Aneurysms in the posterior circulation ( basilar artery , vertebral arteries and posterior communicating artery ) have a higher risk of rupture. (wikipedia.org)
  • A total of 16 craniotomies were performed and 16 aneurysms were clipped under adenosine-induced asystole (in 8 basilar arteries, 7 internal carotid arteries, and 1 middle cerebral artery) in 14 patients (8 females, 6 males). (springer.com)
  • Intracranial aneurysms are 'blisters' which form within the arteries at the base of the brain. (clinicaltrials.gov)
  • Aneurysms most frequently occur in the arteries that bring blood to the brain. (marketpublishers.com)
  • In ~95% of cases, SAH is caused by the rupture of a saccular intracranial aneurysm (sIA) at the fork of intracranial extracerebral arteries in contrast to their infrequent fusiform, mycotic, and traumatic aneurysms. (diabetesjournals.org)
  • Elvidge A. R. and Feindel W. H. Surgical treatment of aneurysm of the anterior cerebral and of the anterior communicating arteries diagnosed by angiography and electroencephalography. (thejns.org)
  • Intracranial aneurysm (IA) is an abnormal expansion in the intracranial arteries that weakens the arterial wall by consistently pushing the vascular wall outwards, which leads to a higher risk of aneurysm rupture. (spandidos-publications.com)
  • To investigate the safety and effectiveness of recanalization in non-acute occlusion of intracranial internal carotid arteries using the flexible Enterprise self-expanding stent. (bioportfolio.com)
  • A ruptured aneurysm at the junction of the right internal carotid-posterior communicating arteries was clipped 4 hours later. (go.jp)
  • The expression of Mas receptor was detected by immunohistochemistry in samples of human intracranial arteries and aneurysms. (mdc-berlin.de)
  • Observations on the tolerance of the intracranial arteries to catheterization. (springer.com)
  • New information from a team that includes UC researchers, however, indicates that patients with a family history of intracranial aneurysm (an abnormal bulging outward of one of the arteries in the brain) have a 17 times greater rate of rupture than those without such a history and that their aneurysms may therefore need to be managed more aggressively through surgery or endovascular intervention. (uc.edu)
  • The angioarchitecture of the vessels in terms of the course of the blood vessels from the arch of the aorta to the aneurysm, and the angles between the arch and its branches, between the parent and feeding arteries, and between the feeding artery and the aneurysm were measured. (sigmaaldrich.com)
  • Feasibility study to assess safety of treating patients with self expanding stent in intracranial arteries. (bioportfolio.com)
  • Recurrence of intracranial aneurysms in autosomal-dominant polycystic kidney disease. (nih.gov)
  • Patients with autosomal-dominant polycystic kidney disease (ADPKD) carry an increased risk of developing intracranial aneurysms. (ebscohost.com)
  • Rupture of intracranial aneurysm (ICA) is a rare but severe manifestation of autosomal dominant polycystic kidney disease (ADPKD). (ebscohost.com)
  • Background and Purpose: Subarachnoid haemorrhage is a common cause of death in patients with autosomal dominant polycystic kidney disease (ADPKD), but little is known about specific characteristics of subarachnoid haemorrhage and intracranial aneurysms in this group of patients. (ebscohost.com)
  • van Rooij WJ, Sprengers ME, de Gast AN, Peluso JP, Sluzewski M. 3D rotational angiography: the new gold standard in the detection of additional intracranial aneurysms. (medscape.com)
  • Although the value of early diagnosis and early operation has been recognized, there have been very few series emphasizing the necessity of cerebral angiography for detecting unruptured intracranial aneurysms in patients with PKD. (thejns.org)
  • 4, 10 Furthermore, there has been no report of the use of angiography in the diagnosis of unruptured aneurysms in PKD patients. (thejns.org)
  • December 3, 2013 -- CHICAGO - If and when it is ready for routine clinical use, 7-tesla time-of-flight (TOF) MR angiography (MRA) will provide "superior assessment" of aneurysms and related vessel features, according to a study presented on Tuesday at RSNA 2013. (auntminnie.com)
  • Digital subtraction angiography (DSA) is still considered the gold standard among the currently used imaging methods for the diagnosis of an intracranial aneurysm. (hindawi.com)
  • MR angiography is widely used in the evaluation of intracranial abnormalities, including intracranial aneurysms (1, 2) . (ajnr.org)
  • However, MR angiography sometimes fails to depict intracranial aneurysms. (ajnr.org)
  • Previous work by Isoda et al (4) has documented the signal intensity in models of lateral and terminal saccular aneurysms with different neck sizes using 3D time-of-flight (TOF) MR angiography with various imaging parameters. (ajnr.org)
  • In that study, noncontrast 3D TOF MR angiography showed terminal saccular aneurysms, or aneurysms with wider necks, or both better than it did lateral saccular aneurysms, aneurysms with narrower necks or both. (ajnr.org)
  • Screening for unruptured asymptomatic intracranial aneurysms in patients undergoing coronary angiography. (currentprotocols.com)
  • MR angiography of intracranial aneurysms: A comparison of 0.5 T and 1.5 T Comput. (currentprotocols.com)
  • CT angiography, however, may demonstrate aneurysms as small as 2 to 3 mm and may be useful for monitoring patients during follow-up. (aafp.org)
  • Magnetic resonance angiography (MRA) is cited as a useful tool for screening, particularly for aneurysms that measure more than 3 to 5 mm in diameter. (aafp.org)
  • The report notes that the gold standard for the diagnostic evaluation of intracranial aneurysms is intraarterial catheter angiography. (aafp.org)
  • Fletcher T. M. Taveras J. M. and Pool J. L. Cerebral vasospasm in angiography for intracranial aneurysms. (thejns.org)
  • A total of 25 patients underwent follow-up digital subtraction angiography (DSA) at 3-21 months postintervention, in whom there were 22 cases with complete occlusion, 2 cases with recurrence of aneurysm neck, and 1 case with in-stent restenosis, but there was no patient with neurologic deficits.The Enterprise stent-assisted coiling embolization can be a safe and effective technique for treatment of very small ruptured intracranial aneurysms. (bioportfolio.com)
  • digital subtraction angiography showed a left posterior communicating artery aneurysm, which was treated by coiling. (hkmj.org)
  • Individualized threshold values of the likelihood ratio of harbouring an aneurysm, for ordering four-vessel angiography are suggested, depending on the prior probability of harbouring an aneurysm, the risks of unnecessary angiography and the risk of living with an undetected aneurysm. (eur.nl)
  • For patients with a three times increased prior risk of harbouring an intracranial aneurysm, the benefit of ADA compared to angiography increases to 0.05 life year. (eur.nl)
  • To create realistic three-dimensional (3D) vascular models from 3D time-of-flight magnetic resonance angiography (3D-TOF MRA) of an intracranial aneurysm (IA). (springer.com)
  • Wang JL, Yuan ZG, Qian GL, Bao WQ, Jin GL: 3D printing of intracranial aneurysm based on intracranial digital subtraction angiography and its clinical application. (springer.com)
  • Zhou LQ, Lou MW, Chen GC, Jiu ZS, Shen YX, Lu L: Value of 640-slice 3D CT angiography plus 3D printing for improving surgeries for intracranial aneurysms. (springer.com)
  • Patients with IAs diagnosed by computed tomography angiography(CTA), magnetic resonance angiography(MRA) or digital subtraction angiography(DSA) has at least one aneurysm. (springermedizin.de)
  • The objective is to apply the Computed Tomographic Angiography (CTA) on assessing the risk factors of intracranial aneurysm rupture, providing the reference for the prevention of intracranial aneurysm rupture. (alliedacademies.org)
  • In this report, the global Intracranial Aneurysm market is valued at USD XX million in 2021 and is projected to reach USD XX million by the end of 2025, growing at a CAGR of XX% during the period 2021 to 2025. (marketpublishers.com)
  • SAN FRANCISCO , April 22, 2020 /PRNewswire/ -- The global intracranial aneurysm market size is anticipated to reach USD 1.92 billion by 2027 , expanding at a CAGR of 8.8% over the forecast period, according to a new report by Grand View Research, Inc. Increasing prevalence of brain aneurysm in several countries and increasing number of patients suffering from hypertension are driving the market. (prnewswire.co.uk)
  • The Global Intracranial Aneurysm Market is segmented further based on Type, Condition, Treatment Type, End-User, and Geography. (yahoo.com)
  • The report offers a comprehensive evaluation of the Global Intracranial Aneurysm Market. (yahoo.com)
  • Temporary parent vessel clip occlusion in aneurysm surgery is not always practical or feasible. (springer.com)
  • The primary hypothesis is that flow diversion can be performed with an 'acceptable' immediate complication rate, defined as less than 15% morbidity and mortality, AND increase the number of patients experiencing successful therapy, defined as complete or near complete occlusion of the aneurysm from 75 to 90%, relative to best standard treatment. (clinicaltrials.gov)
  • Rate of success increases from 75% to 90%, with success defined as complete or near complete occlusion of the aneurysm combined with a modified Rankin score of less or equal to 2. (clinicaltrials.gov)
  • Patients without Intracranial Vascular Lesions Recordings were made in six patients in whom intracranial vascular lesions had been angiographically proven to be obliterated by operation or balloon occlusion, and in one patient who had a normal arteriogram but who was suspected of having an unruptured intracranial aneurysm on the basis of computerized tomography scanning. (thejns.org)
  • Complete (100%) or nearly complete (95-99%) occlusion was achieved in 34 of 38 aneurysms. (ajnr.org)
  • The authors report a case of recurrent subarachnoid hemorrhage (SAH) after complete occlusion of an intracranial aneurysm. (koreamed.org)
  • The Use of Single Stent-Assisted Coiling in Treatment of Bifurcation Aneurysms: A Multicenter Cohort Study With Proposal of a Scoring System to Predict Complete Occlusion. (bioportfolio.com)
  • For patients in the PUFS study, the primary effectiveness end point was complete occlusion of the aneurysm and absence of parent vessel stenosis greater than 50% at 180 days. (nice.org.uk)
  • Specific genes have also had reported association with the development of intracranial aneurysms, including perlecan, elastin, collagen type 1 A2, endothelial nitric oxide synthase, endothelin receptor A and cyclin dependent kinase inhibitor. (wikipedia.org)
  • Scientific evidence suggests that a genetic component plays an important role in the development of intracranial aneurysms, however the specific genes have not been identified. (clinicaltrials.gov)
  • The identification of susceptibility genes, along with a better understanding of environmental interactions such as cigarette smoking, may result in preventing the development of intracranial aneurysms and/or intracranial aneurysm ruptures in people who are at risk for this condition. (clinicaltrials.gov)
  • Flow-Diverter Silk Stent for the Treatment of Intracranial Aneurysms: 1-year Follow-Up in a Multicenter Study. (medscape.com)
  • Yang X, Wu Z, Mu S, Li Y, Lv M. Endovascular treatment of giant and large intracranial aneurysms using the neuroform stent-assisted coil placement. (medscape.com)
  • Intracranial hemorrhage associated with stent-assisted coil embolization of cerebral aneurysms: a cautionary report. (medscape.com)
  • CODMAN ENTERPRISE 2 Intracranial Aneurysm Stent Released in U.S. (medgadget.com)
  • Bedside monitoring offers the opportunity to improve outcomes of intracranial aneurysm patients undergoing stent deployment by individualizing therapy.This trial is designed to demonstrate the superiority of a strategy of platelet function monitoring with dose adjustment in suboptimal responders as compared to a more conventional strategy without monitoring and without dose adjustment to reduce the primary end point evaluated 6 months after stent deployment in patients with intracranial aneurysms. (clinicaltrials.gov)
  • Our first hypothesis is that a strategy of dose adjustment of OAT based on biological monitoring reduces the rate of the combined ischemic endpoints of death, stent thrombosis and stroke as compared to a conventional strategy (local practice without monitoring) in patients scheduled for intracranial stent implantation and followed up for six months. (clinicaltrials.gov)
  • Treatment methods include two major intervention options: clipping of the aneurysm and endovascular methods such as coiling, stent-assisted coiling, and flow diversion stents. (biomedsearch.com)
  • A novel approach is proposed in this study using a magnetic strategy to address the current disadvantages of detachable coils and stent grafts for aneurysm/pseudoaneurysm treatment. (nsti.org)
  • Treatment considerations and dilemmas in stent-assisted coiling of ruptured intracranial aneurysms. (ebscohost.com)
  • Therapeutic effect of enterprise stent-assisted embolization for very small ruptured intracranial aneurysms. (bioportfolio.com)
  • stent has been widespread used in wide-necked intracranial aneurysms and good efficacy has been achieved, but there are few reports on its applications in very small ruptured intracranial aneurysms in literatures. (bioportfolio.com)
  • This study aimed to evaluate the safety and efficacy of Enterprise stent-assisted coiling embolization of very small ruptured intracranial aneurysms.We retrospectively reviewed the clinical and imaging data from 37 patients with very small ruptured intracranial aneurysms who had SAC using Enterprise stents performed from February 2012 to July 2016 in our department. (bioportfolio.com)
  • Stent-assisted coiling embolization of middle cerebral artery trifurcation wide-necked aneurysms. (bioportfolio.com)
  • The aim of this study was to examine the effects of stent-assisted coiling embolization of middle cerebral artery (MCA) trifurcation wide-necked aneurysms in clinical practice. (bioportfolio.com)
  • Long term follow-up of bifurcation aneurysms treated with braided stent assisted coiling and complex T- and Y- stent constructs. (bioportfolio.com)
  • Stent assisted coil embolization (SACE) of bifurcation aneurysms is challenging. (bioportfolio.com)
  • The development of stent-assisted coiling has allowed for the endovascular treatment of wide-necked bifurcation aneurysms. (bioportfolio.com)
  • To evaluate the safety and feasibility of the Cordis Neurovascular Self-Expanding Stent System to facilitate endovascular coil embolization of wide neck saccular intracranial aneurysms. (bioportfolio.com)
  • To investigate the long-term effects of intracranial implantation of Enterprise stent system versus antiplatelet medication on neurologic deficits, daily living abilities, and carotid arte. (bioportfolio.com)
  • Material and Methods: Among 761 intracranial aneurysms which were treated either surgically or endovascularly, 32 rTIAs underwent stent-assisted coiling with LVIS device between 2014 and 2017. (medworm.com)
  • Among 318 aneurysms treated by coil embolization in 267 patients, 16 patients who were treated by bailout stent deployment were retrospectively reviewed. (scialert.net)
  • Bailout self-expandable stent deployment may be a feasible and effective method for relief/prevention of parent artery compromise or coil migration caused by prolapsed or unstable coil loops during embolization of aneurysms. (scialert.net)
  • Intravascular stent and endovascular coil placement for a ruptured fusiform aneurysm of the basilar artery. (springer.com)
  • Intracranial stent placement to trap an extruded coil during endovascular aneurysm treatment: technical note. (springer.com)
  • Hemodynamic changes due to stent placement in bifurcating intracranial aneurysms. (springer.com)
  • Usefulness of the Neuroform stent for the treatment of cerebral aneurysms: results at initial (3-6-mo) follow-up. (springer.com)
  • Various parameters may influence intracranial aneurysm thrombosis, including the flow reduction induced by flow-diverter stent implantation, which is assumed to play a leading role. (epfl.ch)
  • CONCLUSIONS: We propose an innovative approach to measure intracranial flow changes after flow-diverter stent implantation. (epfl.ch)
  • Stent-assisted coiling of intracranial aneurysms using LEO stents: long-term follow-up in 153 patients. (bioportfolio.com)
  • Coiling associated with placement of a self-expandable intracranial stent has improved the treatment of intracranial wide-necked aneurysms. (bioportfolio.com)
  • The LVIS Blue is an FDA-approved stent with 28% metallic coverage that is indicated for use in conjunction with coil embolization for the treatment of intracranial aneurysms. (bioportfolio.com)
  • Intracranial aneurysm , also known as brain aneurysm , is a cerebrovascular disorder in which weakness in the wall of a cerebral artery or vein causes a localized dilation or ballooning of the blood vessel . (wikipedia.org)
  • In previous work, we looked at the effect of aspirin on brain aneurysm, and other research supported our findings that aspirin decreased the risk of rupture," reported Hasan, whose group validated this finding in animal studies. (medscape.com)
  • Our research indicates that treatment of unruptured brain aneurysm has become exceedingly safer over the last 10 years due to advancement in both microsurgical techniques and endovascular technology. (news-medical.net)
  • For instance, in April 2019 , Stryker launched flow diverter for the treatment of brain aneurysm. (prnewswire.co.uk)
  • Thus, increasing number of patients suffering from this disorder is significantly fueling the brain aneurysm treatment market growth. (prnewswire.co.uk)
  • In addition, technological advancements in the endovascular treatment of intracranial aneurysm are expediting the overall brain aneurysm market growth. (prnewswire.co.uk)
  • However, factors such as high treatment costs and unrecognized symptoms of the brain aneurysm are likely to restrain the market growth. (yahoo.com)
  • Flow diverters are now widely used and for many, have become the go to option for the treatment of complex aneurysms" explains Professor Patrick Brouwer Senior Consultant Neurointerventionalist at Karolinska University Hospital and Evaluator for BRAVO Flow Diverter. (news-medical.net)
  • I believe the design of the BRAVO Flow Diverter, particularly the proximal and distal expansion rings, provides a fresh approach to treat aneurysms. (news-medical.net)
  • 1. Stryker Corp has launched its Surpass Evolve flow diverter (a 64-wire cobalt-chromium flow diverter) in the US for redirecting blood flow and handling aneurysm healing. (yahoo.com)
  • BACKGROUND AND PURPOSE: Flow-diverter stents are widely used for the treatment of wide-neck intracranial aneurysms. (epfl.ch)
  • Embolization of the aneurysm with placement of platinum GDC coils from inside the blood vessel through a catheter in the groin. (emoryhealthcare.org)
  • The research compares two treatments for unruptured intracranial aneurysms: microsurgical clipping and endovascular embolization. (news-medical.net)
  • The patient was undergoing embolization treatment of a unruptured amorphous aneurysm measuring 3. (fda.gov)
  • Endovascular embolization of unruptured cerebral aneurysms is an effective therapeutic alternative to neurosurgical clipping and is associated with low morbidity and mortality rates. (ajnr.org)
  • A retrospective study was made of ten patients who were treated by coil embolization of posterior communicating artery aneurysm caused. (ebscohost.com)
  • Self-expandable stents are an effective tool for coil embolization of wide-neck intracranial aneurysms. (scialert.net)
  • A ruptured aneurysm in the anterior communicating artery was clipped 3 hours later. (go.jp)
  • The purpose of this article was to evaluate the outcomes of aneurysms treatment with pipeline flex vs. Pipeline classic. (fda.gov)
  • Outcomes were aneurysm rupture and overall survival after diagnosis. (springer.com)
  • Intracranial aneurysms: review of current treatment options and outcomes. (biomedsearch.com)
  • Studies reporting on the risk of rupture and outcomes have provided much insight, but the debate remains of how and when unruptured aneurysms should be managed. (biomedsearch.com)
  • Patterns of treatment and associated short-term outcomes of unruptured intracranial aneurysms in children. (ebscohost.com)
  • Background: The rates and outcomes of treatments for intracranial aneurysms have not been exclusively determined within the pediatric population. (ebscohost.com)
  • Clinical outcomes were evaluated by the Glasgow Outcome Scale (GOS).Enterprise stents were successfully implanted in all 37 patients with very small ruptured intracranial aneurysms. (bioportfolio.com)
  • Areas covered: The use of FDs in off-label, distal intracranial locations has been increasing with promising outcomes and has given rise to the LPBS, which has less flow-diverting properties, allowing for easier use in distal branching sites through 0.017ʹ microcatheters. (eur.nl)
  • Chapter 1: The pathogenesis of saccular intracranial aneurysms. (uva.nl)
  • We investigated which aneurysm-related risk factors for rupture best discriminate ruptured versus unruptured saccular intracranial aneurysms (sIAs) in subarachnoid hemorrhage patients with multiple sIAs. (ovid.com)
  • Traumatic middle cerebral artery aneurysm: case report and review of the literature. (ebscohost.com)
  • A case of traumatic middle cerebral artery aneurysm was presented. (ebscohost.com)
  • Epilepsy occurred most frequently (35%) with middle cerebral artery aneurysms, especially if moderate or severe operative trauma was sustained and there was postoperative dysphasia. (bmj.com)
  • As a result of their low incidence, most of the studies on intracranial aneurysms associated with middle cerebral artery (MCA) anomalies were presented as case reports or small case series. (frontiersin.org)
  • Brain surgery with placement of a clip around the neck of the aneurysm. (emoryhealthcare.org)
  • Two radiologists assessed the two sets of MR angiograms for the aneurysm dome, neck, parent vessel, vessel tissue contrast, and image impairment due to any artifacts. (auntminnie.com)
  • The indications for surgery were partial treatment (3), growth of residual neck (2), persistent mass effect of a giant aneurysm (1), mass effect from the coil ball (2), coil migration (2), and coil protrusion with embolic event (1). (nih.gov)
  • In two cases it was possible to place a clip across the neck of the aneurysm without removing the coils, as the coils no longer occupied the neck. (nih.gov)
  • Summary: We used tagged MR imaging to investigate the flow in two lateral and two terminal saccular intracranial aneurysm models of different neck sizes. (ajnr.org)
  • The flow in the saccular aneurysm models varied with the shape and size of the neck: flow was faster in wider-necked aneurysms than in those with narrower necks. (ajnr.org)
  • The purpose of this study was to use tagged MR imaging to depict the flow in lateral and terminal saccular intracranial aneurysm models of different neck sizes. (ajnr.org)
  • Tag stripes in the lateral saccular aneurysm model with a neck size of 10 mm rotated faster than those in the aneurysm model with a neck size of 2.5 mm ( Figs 3 and 4 ). (ajnr.org)
  • Although a tag stripe in the terminal saccular aneurysm model with a neck size of 2.5 mm rotated slowly ( Figs 6 and 7 ), no distinct tag stripe in the model with a neck size of 10 mm was recognized ( Fig 8 ), probably because of the very fast flow. (ajnr.org)
  • Tagged MR images of the lateral saccular aneurysm model with a neck size of 2.5 mm. (ajnr.org)
  • Flow diverters are designed to induce disruption of flow near the aneurysm neck while preserving flow into parent vessel and adjacent branches. (ahajournals.org)
  • Preliminary clinical series document effective treatment of wide-neck and/or large and giant aneurysms with acceptable complication rates. (ahajournals.org)
  • Surgical methods included direct clipping of the aneurysm neck, parent artery reconstruction, proximal artery ligation, trapping and wrapping. (biomedsearch.com)
  • It consists of a patch facing the aneurysm neck defect capable of reducing the flow inside it and bridging the aneurysm neck. (nsti.org)
  • To test the feasibility of this approach, we have enhanced the cellular uptake of nanoparticles via electroporation for magnetic cell delivery, so that improved cell guidance and retention on the patch will be conferred for rapid favorable healing of the aneurysm neck. (nsti.org)
  • The mean aneurysm neck width was 8.8 mm. (nice.org.uk)
  • Of the 116 patients treated by the intracranial approach 27.5% developed epilepsy, in contrast with only 5% of the 36 patients who had carotid artery ligation in the neck. (bmj.com)
  • The "remodelling technique" in the treatment of wide neck intracranial aneurysms. (springer.com)
  • Flow changes caused by the sequential placement of stents across the neck of sidewall cerebral aneurysms. (springer.com)
  • Recent studies have demonstrated that morphological and hemodynamic factors, including aneurysm size, neck size, size ratio (SR), aspect ratio (AR), wall shear stress (WSS), and oscillatory shear index (OSI), are associated with the rupture status of intracranial aneurysms ( 5 - 8 ). (frontiersin.org)
  • Endovascular treatment of wide-neck intracranial aneurysms (IAs) is challenging, especially in bifurcation location. (bioportfolio.com)
  • To be eligible for inclusion in the analysis, patients were required to harbor multiple saccular IAs and to have ≥1 designated primary aneurysms treated by surgical/endovascular means. (medscape.com)
  • The indications for adenosine use were proximal control in narrow surgical corridors in 11 cases, aneurysm softening in 4 cases, and aneurysm rupture in 1 case. (springer.com)
  • Sughrue ME, Saloner D, Rayz VL, Lawton MT. Giant intracranial aneurysms: evolution of management in a contemporary surgical series. (springer.com)
  • Background and Purpose- The goal of this study was to investigate predictive preictal risk factors for fatal subarachnoid hemorrhage (SAH) in a patient population with verified intracranial aneurysms without surgical selection of patients and with complete follow-up. (ahajournals.org)
  • 7-10 Besides severity of bleeding, outcome after SAH may be influenced by such preictal factors as patient age, 4,11-13 aneurysm site 4 and size (in surgical SAH cases), 4 history of hypertension, 11,13 and heavy alcohol drinking. (ahajournals.org)
  • In patients with aneurysms in the posterior circulation and in patients with infraclinoidal or giant aneurysms, we favored endovascular techniques because of the more complicated or impossible surgical approach. (ajnr.org)
  • 1998. Unruptured intracranial aneurysms: Risk of rupture and risks of surgical intervention. (currentprotocols.com)
  • According to the report, surgical morbidity is increased when aneurysms have large ill-defined or fusiform necks, arise from atherosclerotic or distended vessels, involve major intracranial bifurcations or are located partially within the cavernous sinus or arise from the midportion of the basilar artery. (aafp.org)
  • Benson D. F. Conservative vs. surgical treatment of cerebral aneurysms. (thejns.org)
  • An analysis of 69 aneurysms treated mainly by direct surgical attack. (thejns.org)
  • Clinical characteristics and surgical treatment of patients with giant intracranial aneurysms. (biomedsearch.com)
  • BACKGROUND: Compared with smaller aneurysms, giant intracranial aneurysms (GICAs) have a poorer prognosis and require more meticulous surgical planning and techniques to exclude them from the circulation. (biomedsearch.com)
  • Until recently, this exclusively involved the surgical clipping of the ruptured aneurysm via a craniotomy. (bmj.com)
  • One-hundred-and-fifty-two patients who underwent surgery for intracranial aneurysm were studied to determine the incidence of postoperative epilepsy in relation to the site of the aneurysm and the type of surgical approach. (bmj.com)
  • Small unruptured intracranial aneurysms rarely require surgical or endovascular interventions, with doctors preferring instead to manage them medically by urging patients to quit smoking or to control their blood pressure. (uc.edu)
  • Both clipping (isolating an aneurysm from normal circulation via a surgical procedure) and coiling (a minimally invasive procedure that accesses the aneurysm from within the bloodstream) carry potential risks, particularly in older patients, so physicians have historically managed small aneurysms medically by controlling hypertensions and/or counseling the patient to quit smoking. (uc.edu)
  • Long-term, serial screening for intracranial aneurysms in individuals with a family history of aneurysmal subarachnoid haemorrhage: a cohort study. (medscape.com)
  • The annual incidence of subarachnoid haemorrhage resulting from the rupture of intracranial aneurysms is estimated to be nine per 100,000. (nih.gov)
  • These criteria required that the report be a systematic review of studies assessing the risk of subarachnoid haemorrhage in patients known to have an unruptured intracranial aneurysm or of studies that had investigated the characteristics of people who experienced a subarachnoid haemorrhage without previously being known to have an unruptured aneurysm. (nih.gov)
  • This has shown that the following factors appear to be associated with a higher risk of subarachnoid haemorrhage: being a woman, older age, posterior circulation aneurysms, larger aneurysms, previous symptoms, "non-white" ethnicity, hypertension, low body mass index, smoking and alcohol consumption of more than 150 g per week. (nih.gov)
  • Characteristics of intracranial aneurysms and subarachnoid haemorrhage in patients with polycystic kidney disease. (ebscohost.com)
  • Results: Life years are lost at all ages by repairing anterior circulation aneurysms under 7 mm in diameter in patients with no history of a subarachnoid haemorrhage from another aneurysm (incidental). (ebscohost.com)
  • The exceptions are patients with remaining life expectancy less than 15-35 years or aged 45-70 (depending on aneurysm size and location) and patients with aneurysms of the anterior circulation under 7 mm in diameter with no history of a previous subarachnoid haemorrhage. (ebscohost.com)
  • When compared to patients under 65 years diagnosed with a UIA, "over 80" patients had a significantly higher incidence of hypertension, and a significantly lower incidence of smoking history and familial aneurysm history. (springer.com)
  • However, several questions remain unanswered related to the incidence and mechanisms of aneurysm rupture after treatment with flow diverters, fate of small perforating vessels, and long-term patency rates. (ahajournals.org)
  • The incidence and treatment of asymptomatic, unruptured cerebral aneurysms. (currentprotocols.com)
  • Birse S. H. and Tom M. I. Incidence of cerebral infarction associated with ruptured intracranial aneurysms. (thejns.org)
  • However there is a higher incidence of multiple aneurysm formation in the methionine group, and the aneurysm size was larger. (cns.org)
  • Homozygous mutant adults exhibit increased incidence of intracranial hemorrhages, which become more prominent with age and after cardiovascular stress. (biologists.org)
  • We determined the rates of endovascular and microsurgical treatments for unruptured intracranial aneurysms (UIA) and associated rates of favorable. (ebscohost.com)
  • Understanding their initiation, growth, and rupture or stabilization may identify those hemodynamic features that lead to aneurysm instability and rupture. (intechopen.com)
  • They can precisely depict not only the presence of an aneurysm but they can also provide valuable information regarding the size, the shape, and the hemodynamic flow characteristics of an intracranial aneurysm. (hindawi.com)
  • Computational fluid dynamics (CFD) holds an important position in the investigation of hemodynamic factors in aneurysms because of its higher resolution near the walls relative to experimental methods such as laser Doppler velocimetry, particle image velocimetry, and magnetic resonance imaging, which is required to compute hemodynamic factors such as shear stress correctly [ 8 , 9 ]. (hindawi.com)
  • Evidence shows that combined samples, including different sizes of aneurysm, might influence hemodynamic results in the assessment of rupture status, with larger aneurysms usually being characterized with low WSS ( 9 , 10 ). (frontiersin.org)
  • Hemodynamics are considered a risk factor for the initiation, growth and rupture of intracranial aneurysms. (uva.nl)
  • In this thesis several aspects of the research of hemodynamics in intracranial aneurysms are discussed. (uva.nl)
  • First, I discuss the need to obtain aneurysm hemodynamics in a patient-specific manner, followed by possible clinical routines for obtaining such information. (uva.nl)
  • Third, the main outcome of the comparison study in chapter 10 is absence of additional value of aneurysm hemodynamics for characterization of ruptured versus unruptured aneurysm. (uva.nl)
  • Hemodynamics in cerebral blood vessels plays a key role in the lifetime cycle of intracranial aneurysms (IA). (intechopen.com)
  • Detailed analysis of the quality of the aneurysm wall under the microscope, together with histological assessment of the aneurysm wall and CFD modeling, can help in building complex knowledge on the relationship between the biology of the wall and hemodynamics. (intechopen.com)
  • The effects of Reynolds and Womersley numbers on the hemodynamics of two simplified intracranial aneurysms (IAs), that is, sidewall and bifurcation IAs, and a patient-specific IA are investigated using computational fluid dynamics. (hindawi.com)
  • Previous works [ 7 , 19 ] have shown the significant effect of aneurysm geometry on the aneurysm hemodynamics, which is not investigated further here. (hindawi.com)
  • Chung BJ, Mut F, Putman CM, Hamzei-Sichani F, Brinjikji W, Kallmes D, Jimenez CM, Cebral JR. Identification of Hostile Hemodynamics and Geometries of Cerebral Aneurysms: A Case-Control Study. (umassmed.edu)
  • In addition, there have been clinical observations indicating thrombus formation following aneurysm endovascular treatment perhaps due to altered hemodynamics. (aps.org)
  • Rodriguez-Hernandez A, Lawton MT. Management of a recurrent coiled giant posterior cerebral artery aneurysm with trapping and thrombectomy: 3-dimensional operative video. (springer.com)
  • The neurosurgical approach during operation of IA allows direct visualization of the aneurysm sac and its sampling in many cases. (intechopen.com)
  • Before 1979, unruptured intracranial aneurysms were not operated on in our clinic, which, until the late 1960s, was the only neurosurgical center in Finland. (ahajournals.org)
  • In aneurysms for which either endovascular or neurosurgical treatment seemed appropriate, the patients chose to be treated via an endovascular route. (ajnr.org)
  • The article presents a comment on the impact of the International Subarachnoid Aneurysm Treatment Trial (ISAT) on neurosurgical practice. (ebscohost.com)
  • Background: Ruptured tiny intracranial aneurysms (TIAs) have been challenging both for endovascular and neurosurgical interventions. (medworm.com)
  • Epilepsy after two different neurosurgical approaches to the treatment of ruptured intracranial aneurysm. (bmj.com)
  • International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomized trial. (springer.com)
  • Objectives Our aim was to provide nationwide age-standardised rates (ASR) on the usage of endovascular coiling and neurosurgical clipping for unruptured intracranial aneurysm (UIA) treatment in Germany. (bmj.com)
  • These data further suggest that mutations in COL22A1 could be one of the risk factors for intracranial aneurysms in humans. (biologists.org)
  • Sturiale CL, Brinjikji W, Murad MH, Lanzino G. Endovascular Treatment of Intracranial Aneurysms in Elderly Patients: A Systematic Review and Meta-Analysis. (medscape.com)
  • Safety and efficacy of adjunctive balloon remodeling during endovascular treatment of intracranial aneurysms: a literature review. (springer.com)
  • Additional information gathered by the researchers included demographics, present comorbidities, family and individual medical history, aneurysm size and location in the brain, rupture status of designated primary aneurysms, angiographic features of the aneurysm, treatment modalities, and whether the patient used a daily dose of ≥81 mg of aspirin. (medscape.com)
  • Angiographic frequency of anterior circulation intracranial aneurysms. (currentprotocols.com)
  • Recent guidelines and an evidence-based systematic review of the literature have formulated recommendations for the care of patients with unruptured intracranial aneurysms, principally based on age, history, and aneurysm size. (medscape.com)
  • Clipping versus coiling for ruptured intracranial aneurysms: a systematic review and meta-analysis. (medscape.com)
  • This article describes a systematic review of systematic reviews performed to investigate factors that might influence the risk of rupture of an intracranial aneurysm. (nih.gov)
  • Prevalence and risk of ruptured of intracranial aneurysms: A systematic review. (currentprotocols.com)
  • The Woven EndoBridge (WEB) for endovascular therapy of intracranial aneurysms: Update of a systematic review with meta-analysis. (bioportfolio.com)
  • Other factors include the presence or absence of symptoms, the patient's medical condition and the size, morphology and location of the aneurysm. (aafp.org)
  • The size/location of the aneurysm, technical feasibility, successful stabilization rate, and procedure-related complications were evaluated. (scialert.net)
  • Likewise, asymptomatic patients that need to be investigated for the presence of an intracranial aneurysm should undergo a minimally invasive diagnostic procedure, as CTA or MRA. (hindawi.com)
  • Intracranial aneurysms are present in roughly 5% of the population, yet most are often asymptomatic and never detected. (biomedsearch.com)
  • Recent technological advances in imaging modalities, along with increased understanding of natural history and prevalence of aneurysms, have increased detection of asymptomatic unruptured intracranial aneurysms (UIA). (biomedsearch.com)
  • Autopsy reports have shown that aneurysms are present in roughly 5% of the population, yet most are often asymptomatic (Menghini et al. (biomedsearch.com)
  • We conclude that acoustic detection has the potential of becoming a useful tool in the non-invasive diagnosis of occult, asymptomatic intracranial aneurysms. (eur.nl)
  • Conclusions- Increased systolic blood pressure values and long-term hypertension before aneurysm rupture seem to predict fatal SAH independently of aneurysm size or patient age or sex at the time of rupture. (ahajournals.org)
  • Conclusions: Repair of unruptured aneurysms benefits patients harbouring them by improving life expectancy except in certain circumstances. (ebscohost.com)
  • Conclusions- Intracranial aneurysms are common in HbSS SCD. (medworm.com)
  • At Emory is a national leader, specializing in the treatment of aneurysms using the GDC (Guglielmi Detachable) Coils. (emoryhealthcare.org)
  • The studies were Pipeline for Intracranial Treatment of Aneurysms (PITA) and Pipeline for Uncoilable or Failed aneurysms (PUFS). (nice.org.uk)
  • Moreover, with the emergence of new technologies and approaches for the treatment of aneurysms, the field of neurovascular intervention is only likely to expand further. (bmj.com)
  • [5] [6] Symptoms of a subarachnoid hemorrhage differ depending on the site and size of the aneurysm. (wikipedia.org)
  • The size of the aneurysm, whether you smoke, and how weak your blood vessels are all play a part in determining when, or if, an aneurysm will burst. (baycare.org)
  • 1 , 4 The symptoms of this subtype include cerebrovascular multiple stenosis, aneurysm, and vertebrobasilar dolichoectasia. (dovepress.com)
  • Subarachnoid hemorrhage (SAH) is a common and frequently life-threatening cerebrovascular disease, which is mostly related with a ruptured intracranial aneurysm. (degruyter.com)
  • Wurm G, Lehner M, Tomancok B, Kleiser R, Nussbaumer K: Cerebrovascular biomodeling for aneurysm surgery: simulation-based training by means of rapid prototyping technologies. (springer.com)
  • Unruptured intracranial aneurysms (UIAs) are a common cerebrovascular condition. (bmj.com)
  • In addition, miR-145 has been reported to be downregulated in atherosclerosis, vascular injury and aneurysms ( 21 , 22 ). (spandidos-publications.com)
  • Effective May 25, 2018 , the guidelines of our medical policy, Endovascular Procedures for Intracranial Arterial Disease (Atherosclerosis and Aneurysms) , will also be applied to professional claims for services provided to patients enrolled in Horizon Blue Cross Blue Shield of New Jersey Medicare Advantage (MA) plans. (horizonblue.com)
  • Based on the guidelines of our medical policy, Endovascular Procedures for Intracranial Arterial Disease (Atherosclerosis and Aneurysms) , claims for services provided on and after May 25, 2018 to members enrolled in Horizon BCBSNJ MA plans will be processed as noted below. (horizonblue.com)
  • Adenosine-induced transient asystole for management of a basilar artery aneurysm. (springer.com)
  • Herein, we report a case of a female Pompe patient with complicated giant basilar artery aneurysm. (dovepress.com)
  • In the vast majority of cases, SAH results from the rupture of an intracranial aneurysm. (bmj.com)
  • According to the AHA statement, standard computed tomography (CT) with or without contrast agents cannot adequately exclude or confirm the presence of an intracranial aneurysm, particularly an unruptured aneurysm. (aafp.org)
  • Describe the advantages and disadvantages of this technique for diagnosis of an intracranial aneurysm. (oncologynurseadvisor.com)
  • V. Describe the advantages and disadvantages of the alternative techniques for diagnosis of an intracranial aneurysm. (oncologynurseadvisor.com)
  • We present a further evaluation of an improved recording method for the acoustic detection of intracranial aneurysms (ADA). (eur.nl)
  • Chapter 5: Some patients with intracranial aneurysms have a reduced type III / type I collagen ratio. (uva.nl)
  • RESEARCH DESIGN AND METHODS Kuopio Intracranial Aneurysm Database ( www.uef.fi/ns ) includes all ruptured and unruptured sIA cases from a defined catchment population in eastern Finland since 1980. (diabetesjournals.org)
  • Methods- A total of 142 patients with 181 unruptured aneurysms diagnosed between 1956 and 1978 were followed up for a total of 2577 person-years until death, SAH, or the years 1997 to 2000. (ahajournals.org)
  • However, the geometry and volume of intracranial aneurysm models are highly dependent upon different segmentation methods, even when employed upon the same medical imaging data. (witpress.com)
  • Methods: A life expectancy analysis of patients with unruptured aneurysms with and without repair based on prospective data from the International Study of Unruptured Intracranial. (ebscohost.com)
  • Methods and Results: Human aneurysm tissues were collected by microsurgical clipping and immunostained for phospho-Focal adhesion kinase (FAK) and CD68+ macrophages. (sigmaaldrich.com)
  • Basilar artery aneurysms represent only 3%-5% of all intracranial aneurysms but are the most common aneurysms in the posterior circulation. (wikipedia.org)
  • Fusiform dolichoectatic aneurysms represent a widening of a segment of an artery around the entire blood vessel, rather than just arising from a side of an artery's wall. (wikipedia.org)
  • An aneurysm represents a weak spot in the wall of an artery which results in a "focal bulge" or widening of the artery. (emoryhealthcare.org)
  • Subsequently, the aneurysm coil fiber was then used to wrap and tie down to the external adventitial area of the common femoral artery. (aapc.com)
  • Magnetic resonance imaging (coronal T 2 -weighted with fat suppression) showing an intracranial aneurysm (1.6 × 1.0 × 0.9 cm 3 ) in the left paraophthalmic artery in the left suprasellar region (A) before and (B) after endovascular coiling (arrows). (cmaj.ca)
  • Dissecting aneurysms of the intracranial vertebral artery. (nih.gov)
  • Among 86 patients with aneurysms arising from the vertebral artery or its branches, 24 had dissecting aneurysms. (nih.gov)
  • Local artery anatomical shapes of aneurysms were likewise found to significantly influence segmentation results. (witpress.com)
  • Oculomotor Nerve Palsy Caused by Posterior Communicating Artery Aneurysm: Evaluation of Symptoms after Endovascular Treatment. (ebscohost.com)
  • We report the outcome of endovascular treatment in a series of patients presenting with posterior communicating artery aneurysm causing ocular motor nerve palsy. (ebscohost.com)
  • Efficacy and current limitations of intravascular stents for intracranial internal carotid, vertebral, and basilar artery aneurysms. (springer.com)
  • The collagenous adventitia of the parent artery is modelled as a protective mechanical sheath whereas collagen is modelled as the dominant load bearer in the aneurysm sac. (whiterose.ac.uk)
  • Key factors such as the growing prevalence of strokes and haemorrhages followed by the increasing incidences of hypertension and artery wall disorders amongst the individuals are the common drivers for the growth of the Intracranial Aneurysm Market. (yahoo.com)
  • Brooks M. Does Coiling Beat Clipping for Ruptured Aneurysms? (medscape.com)
  • Harding A. Careful selection key to coiling in elderly aneurysm patients. (medscape.com)
  • standard endovascular coiling of aneurysm with any type of already approved coil. (clinicaltrials.gov)
  • Surgery for intracranial aneurysms that have been treated by endovascular coiling is a new challenge for neurosurgeons and the need for it will undoubtedly continue to increase. (nih.gov)
  • We have reviewed our experience with 11 patients who underwent surgery following endovascular coiling with Guglielmi detachable coils (GDCs) of an aneurysm. (nih.gov)
  • A checklist in the event of aneurysm perforation during coiling. (springer.com)
  • With this new information, Broderick says, We should be thinking more strongly about clipping or coiling small aneurysms in patients with a family history of intracranial aneurysm, because their aneurysms are more likely to rupture if left untreated. (uc.edu)
  • A study of correlation of angioarchitecture of intracranial blood vessels with difficulty during endovascular coiling of aneurysms. (sigmaaldrich.com)