Angiography, Digital Subtraction
Magnetic Resonance Angiography
Aortic Aneurysm, Thoracic
Tomography, X-Ray Computed
Blood Vessel Prosthesis
Glasgow Outcome Scale
Blood Vessel Prosthesis Implantation
Carotid Artery, Internal
Posterior Cerebral Artery
Anterior Cerebral Artery
Circle of Willis
Equipment Failure Analysis
Carotid Artery Diseases
Coated Materials, Biocompatible
Intracranial Arteriovenous Malformations
Sensitivity and Specificity
Image Processing, Computer-Assisted
Prostheses and Implants
Brain Hemorrhage, Traumatic
Polycystic Kidney, Autosomal Dominant
Carotid Artery, Internal, Dissection
Tomography, Spiral Computed
Magnetic Resonance Imaging
Radiographic Image Enhancement
Hematoma, Subdural, Acute
Basal Ganglia Hemorrhage
Middle Cerebral Artery
Oculomotor Nerve Diseases
Reproducibility of Results
3D angiography. Clinical interest. First applications in interventional neuroradiology. (1/2536)3D angiography is a true technical revolution that allows improvement in the quality and safety of diagnostic and endovascular treatment procedures. 3D angiography images are obtained by reconstruction of a rotational angiography acquisition done on a C-arm (GE Medical Systems) spinning at 40 degrees per second. The carotid or vertebral selective injection of a total of 15 ml of non-ionic contrast media at 3 ml/sec over 5 seconds allows the selection of the "arterial phase". Four hundred sixty 3D angiographic studies were performed from December 1996 to September 1998 on 260 patients and have been analyzed in MIP (Maximum Intensity Projection) and SSD (Shaded Surface Display) views. The exploration of intracranial aneurysms is simplified and only requires, for each vascular axis, a biplane PA and Lateral run followed by a single rotational angiography run. The 3D angiography image is available on the workstation's screen (Advantage Workstation 3.1, GE Medical Systems) in less than 10 minutes after the acquisition of the rotational run. It therefore allows one to analyze, during the intervention, the aneurysm's angioarchitecture, in particular the neck, and select the best therapeutic technique. When endovascular treatment is the best indication, 3D angiography allows one to define the optimal angle of view and accurately select the microcoils dimensions. 3D angiography replaces the multiple oblique views that used to be required to analyze the complex aneurysms and therefore allows a reduction of the total contrast medium quantity, the patient X-ray dose and the length of the intervention time which is a safety factor. Also, in particular for complex cases, it brings additional elements complementing the results of standard 2D DSA and rotational angiograms. In the cervical vascular pathology, 3D angiography allows for a better assessment of the stenosis level and of dissection lesions. Our current research activities focus on the matching without stereotactic frame between 3D X-ray angiography and volumetric MR acquisition, which should allow us to improve the treatment of intracerebral arterio-venous malformations (AVMs). (+info)
Combination therapy of fasudil hydrochloride and ozagrel sodium for cerebral vasospasm following aneurysmal subarachnoid hemorrhage. (2/2536)Fasudil hydrochloride is a new type of intracellular calcium antagonist, different from the calcium entry blockers that are commonly employed for clinical use. Since September 1995, the combination of fasudil hydrochloride and ozagrel sodium, an inhibitor of thromboxane A2 synthesis, has been used to treat 60 patients at risk of cerebral vasospasm after aneurysmal subarachnoid hemorrhage. The effectiveness of this combination therapy was investigated by comparison with the outcome of 57 patients previously treated with only ozagrel sodium. The combination therapy was significantly more effective (p < 0.01) in reducing the incidence of low density areas on computed tomography scans, and reduced, but not significantly, the occurrence of symptomatic vasospasm. The combination therapy of fasudil hydrochloride and ozagrel sodium has superior effectiveness over only ozagrel sodium in treating patients at risk of vasospasm after aneurysmal subarachnoid hemorrhage. (+info)
Large and giant middle to lower basilar trunk aneurysms treated by surgical and interventional neuroradiological methods. (3/2536)Treatment of large and giant aneurysms of the basilar artery remains difficult and controversial. Three large or giant aneurysms of the lower basilar artery were treated with a combination of surgical and interventional neuroradiological procedures. All patients underwent the balloon occlusion test with hypotensive challenge (blood pressure reduced to 70% of the control value). The third patient did not tolerate the test. In the first patient, both vertebral arteries were occluded through a craniotomy. In the second patient, both the aneurysm and the basilar artery were occluded by detached balloons. In the third patient, one vertebral artery was occluded by surgical clipping and the other by detached helical coils and fiber coils. In spite of anti-coagulation and anti-platelet therapy, postoperative thrombotic or embolic ischemia occurred in the second and third patients. Fibrinolytic therapy promptly corrected the ischemic symptoms, but the second patient developed hemorrhagic complications at the craniotomy area 2 hours later. At follow-up examination, the first patient had only 8th cranial nerve paresis, the second patient who had a hemorrhagic complication was bed-ridden, and the third patient had no deficit. Interventional occlusion requires a longer segment of the parent artery compared to surgical occlusion of the parent artery and might cause occlusion of the perforating arteries. However, selected use of various coils can occlude only a short segment of the parent artery. Thus, the postoperative management of thromboembolic ischemia after the occlusion of the parent artery is easier using the interventional technique. (+info)
Significance of acute cerebral swelling in patients with sylvian hematoma due to ruptured middle cerebral artery aneurysm, and its management. (4/2536)A retrospective study of 75 patients treated surgically for ruptured middle cerebral artery (MCA) aneurysm within 48 hours evaluated clinical grade at admission, secondary development and management of cerebral swelling associated with space-occupying hematoma, cerebral infarction caused by vasospasm, development of hydrocephalus, and clinical outcome. Clinical grade at admission was significantly better in patients without than in those with hematoma (p < 0.01). Twenty-seven patients with sylvian hematoma caused by ruptured MCA aneurysm often developed ipsilateral cerebral swelling in the early period after subarachnoid hemorrhage. Seventeen of these patients developed serious cerebral swelling and received barbiturate therapy. Nine of these 17 patients had good outcome, but six patients died of cerebral swelling. The incidence of hydrocephalus was significantly higher in patients with than in those without hematoma (p < 0.01). The incidence of infarction was more pronounced in patients with sylvian hematoma. Clinical outcome was significantly better in patients without than in those with sylvian hematoma (p < 0.01). Development of cerebral swelling in patients with sylvian hematoma due to ruptured MCA aneurysm has a significant effect on outcome, and improvements in management are required. (+info)
Rupture mechanism of a thrombosed slow-growing giant aneurysm of the vertebral artery--case report. (5/2536)A 76-year-old male developed left hemiparesis in July 1991. The diagnosis was thrombosed giant vertebral artery aneurysm. He showed progressive symptoms and signs of brainstem compression, but refused surgery and was followed up without treatment. He died of rupture of the aneurysm and underwent autopsy in March 1995. Histological examination of the aneurysm revealed fresh clot in the aneurysmal lumen, old thrombus surrounding the aneurysmal lumen, and more recent hemorrhage between the old thrombus and the inner aneurysmal wall. The most important histological feature was the many clefts containing fresh blood clots in the old thrombus near the wall of the distal neck. These clefts were not lined with endothelial cells, and seemed to connect the lumen of the parent artery with the most peripheral fresh hemorrhage. However, the diameter of each of these clefts is apparently not large enough to transmit the blood pressure of the parent artery. Simple dissection of the aneurysmal wall by blood flow in the lumen through many clefts in the old thrombus of the distal neck may be involved in the growth and rupture of thrombosed giant aneurysms of the vertebral artery. (+info)
Primary non-traumatic intracranial hemorrhage. A municipal emergency hospital viewpoint. (6/2536)The devastating natural history of 138 consecutive admissions for non-traumatic intracranial hemorrhage to a major emergency care municipal hospital is reviewed. Sixty-four percent of the patients had demonstrable intracranial hematomas while 36% had mainly subarachnoid hemorrhage. Hypertension was a related condition in 43% of the parenchymal hematoma patients, while proved aneurysms accounted for 74% of the subarachnoid hemorrhage patients. There was only a 14% survivorship for patients requiring emergent surgery. All operated hematoma patients survived delayed surgery with improved level of responsiveness. The overall mortality was 74% for intracranial hematoma patients and 58% for aneurysm-caused subarachnoid hemorrhage patients. (+info)
The use of electrophysiological monitoring in the intraoperative management of intracranial aneurysms. (7/2536)OBJECTIVES: Somatosensory evoked potentials (SSEPs) and brainstem auditory evoked potentials (BAEPs) have been increasingly utilised during surgery for intracranial aneurysms to identify cerebral ischaemia. Between July 1994 and April 1996, we surgically treated 70 aneurysms in 49 consecutive patients (58 operations) with the aid of intraoperative evoked potential monitoring. This study sought to evaluate the usefulness of SSEP and BAEP monitoring during intracranial aneurysm surgery. METHODS: Mean patient age was 51.9 (range 18-79) years. The sizes of the aneurysms were 3-4 mm (15), 5-9 mm (26), 10-14 mm (11), 15-19 mm (seven), 20-24 mm (six), and >25 mm (five). SSEPs were monitored in 58 procedures (100%) and BAEPs in 15 (26%). The neurological status of the patients was evaluated before and after surgery. RESULTS: Thirteen of the 58 procedures (22%) monitored with SSEPs had SSEP changes (12 transient, one persistent); 45 (78%) had no SSEP changes. Three of 15 patients (20%) monitored with BAEPs had changes (two transient, one persistent); 12 (80%) had no BAEP changes. Of the 14 patients with transient SSEP or BAEP changes, these changes resolved with adjustment or removal of aneurysm clips (nine), elevating MAP (four), or retractor adjustment (one). Mean time from precipitating event to electrophysiological change was 8.9 minutes (range 3-32), and the mean time for recovery of potentials in patients with transient changes was 20.2 minutes (range 3-60). Clinical outcome was excellent in 39 patients, good in five, and poor in three (two patients died), and was largely related to pretreatment grade. CONCLUSIONS: SSEPs and BAEPs are useful in preventing clinical neurological injury during surgery for intracranial aneurysms and in predicting which patients will have unfavourable outcomes. (+info)
Cerebral arterial lesions resulting from inflammatory emboli. (8/2536)In order to study the effects of septic embolism on the brain, silicone rubber emboli of various types were injected into the carotid arteries of 35 dogs. Pathologic and angiographic studies were performed to assess the resultant arterial and parenchymal lesions. Pure silicone rubber emboli (14 dogs) produced occasional intra-arterial thrombosis but no arteritis. Sterile and bacterially contaminated emboli containing a lead-chromate pigment (similar to those used in previous studies of septic embolism) (11 dogs) and pure silicone rubber emboli with transversely oriented canals (10 dogs), after brief placement in a bacterial suspension, were associated with intense inflammatory arteritis. This was accompanied by focal meningitis, subarachnoid hemorrhage, thrombosis, and cerebritis of the underlying cortex. The findings resembled those found in mycotic aneurysm. Aneurysmal dilatation was observed in one postmortem angiogram. In previous models of mycotic aneurysm, the inflammation attributed to bacterial contamination was probably due to the lead-chromate pigment used. (+info)
An intracranial aneurysm is a bulge or balloon-like dilation of a blood vessel in the brain. It occurs when a weakened area in the wall of the blood vessel balloons out and forms a sac. This can cause the blood vessel to become stretched and prone to rupture, which can lead to a life-threatening brain hemorrhage. Intracranial aneurysms are most commonly found in the arteries that supply blood to the brain, particularly the anterior communicating artery, the middle cerebral artery, and the internal carotid artery. They can occur at any age, but are more common in people over the age of 50. Risk factors for developing an intracranial aneurysm include smoking, high blood pressure, a family history of the condition, and certain genetic disorders. Treatment options for intracranial aneurysms include surgery to clip or coagulate the aneurysm, or endovascular coiling, which involves inserting a catheter through a blood vessel in the groin and threading it up to the aneurysm, where a coil is placed to fill the aneurysm and prevent it from rupturing.
An aneurysm is a bulge or dilation in the wall of a blood vessel, typically a artery. It occurs when the weakened wall of the vessel balloons out and becomes distended, creating a sac-like structure. Aneurysms can occur in any part of the body, but they are most commonly found in the brain, aorta, and legs. Aneurysms can be caused by a variety of factors, including high blood pressure, atherosclerosis (hardening of the arteries), trauma, and genetic predisposition. They can also be caused by certain medical conditions, such as Marfan syndrome or Ehlers-Danlos syndrome. Aneurysms can be asymptomatic, meaning they do not cause any symptoms, or they can cause symptoms such as headache, neck pain, visual changes, or weakness or numbness in the extremities. If an aneurysm ruptures, it can cause a life-threatening bleeding episode. Treatment for aneurysms depends on the size, location, and risk of rupture. Small aneurysms may be monitored with regular imaging studies, while larger aneurysms or those at high risk of rupture may require surgical repair or endovascular coiling, a minimally invasive procedure in which a catheter is inserted into the aneurysm and a coil is placed to fill the sac and prevent further expansion.
Aneurysm, ruptured refers to a medical condition in which a weakened or bulging blood vessel in the brain or elsewhere in the body bursts or leaks, causing blood to leak out into the surrounding tissue. This can be a life-threatening emergency, as the leaked blood can cause damage to surrounding brain tissue, leading to brain swelling, bleeding, and potentially permanent brain damage or death. Ruptured aneurysms are often caused by high blood pressure, smoking, or a family history of aneurysms. Treatment typically involves surgery or endovascular coiling to repair or clip the ruptured aneurysm and prevent further bleeding.
Subarachnoid hemorrhage (SAH) is a medical condition that occurs when blood leaks into the space between the arachnoid mater and the pia mater, which are two layers of tissue that cover the surface of the brain. This can happen due to a ruptured aneurysm, which is a bulge in a blood vessel in the brain that can burst and cause bleeding. SAH is a serious medical emergency that requires prompt diagnosis and treatment. The symptoms of SAH can include severe headache, nausea and vomiting, sensitivity to light, confusion, and loss of consciousness. If left untreated, SAH can lead to brain damage, stroke, and even death. Treatment for SAH typically involves surgery to repair or remove the ruptured aneurysm, as well as medications to manage symptoms and prevent further bleeding. The prognosis for SAH depends on several factors, including the severity of the bleeding, the location of the aneurysm, and the patient's overall health.
An infected aneurysm is a medical condition in which an aneurysm, which is a bulge or dilation in a blood vessel, becomes infected. This can occur when bacteria or other microorganisms enter the bloodstream and travel to the aneurysm, causing an infection. Symptoms of an infected aneurysm may include fever, chills, fatigue, and pain in the affected area. Treatment typically involves antibiotics to treat the infection and, in some cases, surgical repair of the aneurysm.，，。
An aortic aneurysm is a bulge or dilation in the wall of the aorta, which is the largest artery in the body. It occurs when the wall of the aorta becomes weakened and begins to balloon outwards. Aneurysms can occur in any part of the aorta, but the most common location is in the abdominal aorta, just below the kidneys. Aneurysms can be caused by a variety of factors, including high blood pressure, atherosclerosis (hardening of the arteries), smoking, and genetic conditions such as Marfan syndrome or Ehlers-Danlos syndrome. They can also be caused by injury or infection. Aortic aneurysms can be asymptomatic, meaning that they do not cause any noticeable symptoms. However, if the aneurysm becomes large enough, it can cause pain in the abdomen or back, and in severe cases, it can rupture, leading to life-threatening internal bleeding. Treatment for aortic aneurysms depends on the size and location of the aneurysm, as well as the patient's overall health. Small aneurysms may be monitored with regular imaging tests, while larger aneurysms may require surgery to repair or replace the affected section of the aorta. In some cases, endovascular repair, a minimally invasive procedure, may be used to treat aneurysms.
A heart aneurysm is a bulge or balloon-like enlargement of a weakened portion of the wall of a blood vessel in the heart. It occurs when a section of the wall becomes thin and weak, causing it to balloon outwards. Aneurysms can occur in any blood vessel in the body, but they are most commonly found in the aorta, which is the largest artery in the body and carries blood from the heart to the rest of the body. Heart aneurysms can be caused by a variety of factors, including high blood pressure, atherosclerosis (the buildup of plaque in the arteries), infections, and injuries. They can also be caused by genetic factors, such as Marfan syndrome or Ehlers-Danlos syndrome. Heart aneurysms can be asymptomatic, meaning that they do not cause any noticeable symptoms. However, if an aneurysm becomes large enough, it can cause symptoms such as chest pain, shortness of breath, and palpitations. In some cases, an aneurysm can rupture, which is a life-threatening emergency that requires immediate medical attention. Treatment for heart aneurysms depends on the size and location of the aneurysm, as well as the underlying cause. Small aneurysms may be monitored with regular imaging tests, while larger aneurysms may require surgery or other interventions to prevent rupture. Medications may also be prescribed to manage symptoms or lower the risk of complications.
Aortic aneurysm, thoracic refers to a bulge or dilation in the thoracic aorta, which is the largest artery in the body that carries oxygenated blood from the heart to the rest of the body. The bulge can occur at any point along the length of the thoracic aorta, but it is most commonly found in the ascending aorta, just below the heart. Aortic aneurysms can be caused by a variety of factors, including high blood pressure, atherosclerosis (hardening of the arteries), and genetic conditions such as Marfan syndrome or Ehlers-Danlos syndrome. They can also be caused by trauma or surgery. Aortic aneurysms can be asymptomatic, meaning that they do not cause any noticeable symptoms. However, if the aneurysm becomes large enough, it can cause symptoms such as chest pain, shortness of breath, and a pulsating sensation in the abdomen. If the aneurysm ruptures, it can be life-threatening. Treatment for aortic aneurysms depends on the size and location of the aneurysm, as well as the patient's overall health. Small aneurysms may be monitored with regular imaging tests, while larger aneurysms may require surgery or endovascular repair. It is important for people with aortic aneurysms to follow their doctor's recommendations for monitoring and treatment to prevent complications.
Aneurysm, dissecting refers to a medical condition in which a blood vessel in the body becomes weakened and bulges outwards, creating a tear or split in the vessel wall. This can cause blood to flow into the surrounding tissue, which can lead to serious complications if left untreated. Dissecting aneurysms are typically caused by high blood pressure, atherosclerosis (hardening of the arteries), or trauma to the affected vessel. They can occur in any blood vessel in the body, but are most commonly found in the aorta, the main artery that carries blood from the heart to the rest of the body. Treatment for dissecting aneurysms may include medications to lower blood pressure, surgery to repair or replace the affected vessel, or endovascular procedures to repair the aneurysm from within the blood vessel.
In the medical field, "rupture, spontaneous" refers to the sudden and unexpected tearing or bursting of a structure or organ within the body. This can occur due to a variety of factors, including trauma, disease, or physical stress. For example, a spontaneous rupture of the spleen is a serious medical emergency that can occur when the spleen's blood vessels burst, causing internal bleeding. Similarly, a spontaneous rupture of the aorta, the body's largest artery, can be life-threatening and requires immediate medical attention. Spontaneous ruptures can also occur in other organs and structures, such as the uterus during childbirth, the lung, or the bowel. In these cases, prompt diagnosis and treatment are critical to prevent further complications and improve outcomes.
An iliac aneurysm is a bulge or dilation in the iliac artery, which is one of the main arteries in the body that carries blood from the heart to the lower limbs and pelvic region. The iliac artery branches into two main arteries, the external iliac artery and the internal iliac artery, which supply blood to the legs and pelvic organs, respectively. An iliac aneurysm can occur at any point along the length of the iliac artery, but it is most commonly found in the portion of the artery that lies just above the inguinal ligament, which is the ligament that separates the upper and lower legs. Iliac aneurysms can be caused by a variety of factors, including atherosclerosis (hardening of the arteries), high blood pressure, and genetic factors. They can also be caused by injury or infection. Iliac aneurysms can be asymptomatic, meaning that they do not cause any noticeable symptoms. However, as the aneurysm grows, it can cause pain in the lower abdomen or back, and in severe cases, it can rupture, which can be life-threatening. Treatment options for iliac aneurysms include medication to manage symptoms, lifestyle changes to reduce risk factors, and surgical repair or replacement of the affected artery.
A coronary aneurysm is a bulge or balloon-like dilation of a coronary artery, which is a blood vessel that supplies oxygen-rich blood to the heart muscle. It occurs when the arterial wall weakens and becomes thin, causing it to balloon outwards. Coronary aneurysms can be caused by a variety of factors, including high blood pressure, atherosclerosis (the buildup of plaque in the arteries), and infections such as Kawasaki disease. They can also be a complication of certain medical conditions, such as Marfan syndrome or Ehlers-Danlos syndrome. If left untreated, coronary aneurysms can rupture, causing a heart attack or other serious complications. Treatment options for coronary aneurysms may include medications to manage symptoms and prevent further damage, lifestyle changes such as quitting smoking and eating a healthy diet, and in some cases, surgical repair or removal of the aneurysm.
In the medical field, "platinum" typically refers to a type of chemotherapy drug called a platinum agent. Platinum agents are a class of chemotherapy drugs that are commonly used to treat various types of cancer, including ovarian cancer, testicular cancer, and lung cancer. The most well-known platinum agent is cisplatin, which was first discovered in the 1960s and has been used in cancer treatment for decades. Other platinum agents include carboplatin and oxaliplatin. Platinum agents work by binding to DNA and disrupting the normal process of cell division, which can lead to the death of cancer cells. However, they can also have side effects, including nausea, vomiting, hair loss, and damage to the kidneys and hearing. It's important to note that the use of platinum agents in cancer treatment is highly individualized and depends on a variety of factors, including the type and stage of cancer, the patient's overall health, and their personal preferences.
Aortic rupture is a medical emergency that occurs when the aorta, which is the largest artery in the body, ruptures or tears. This can happen due to a variety of factors, including trauma, atherosclerosis (hardening of the arteries), aneurysms (ballooning of the aorta), and certain medical conditions such as Marfan syndrome or Ehlers-Danlos syndrome. Aortic rupture is a life-threatening condition that requires immediate medical attention. Symptoms of aortic rupture may include severe chest pain, shortness of breath, lightheadedness, and loss of consciousness. If left untreated, aortic rupture can lead to rapid bleeding and death. Treatment for aortic rupture typically involves emergency surgery to repair or replace the damaged section of the aorta. In some cases, aortic rupture may be treated with medications to control blood pressure and prevent further bleeding. It is important to seek medical attention immediately if you suspect that you or someone else may be experiencing aortic rupture.
In the medical field, "aneurysm, false" refers to a condition where a blood vessel in the brain is weakened and bulges outwards, but it is not a true aneurysm. A true aneurysm is a bulge in a blood vessel that can rupture and cause bleeding in the brain, which can be life-threatening. A false aneurysm, also known as a pseudoaneurysm, is a bulge in a blood vessel that is caused by trauma or surgery, but it is not a true aneurysm because the blood vessel wall is not weakened. False aneurysms are typically smaller than true aneurysms and are less likely to rupture, but they can still cause symptoms such as headache, nausea, and vomiting. Treatment for a false aneurysm may involve medications to reduce blood pressure and prevent further bleeding, or surgery to repair the blood vessel. It is important to seek medical attention if you suspect you may have a false aneurysm, as it can be a serious condition if left untreated.
Intracranial thrombosis refers to the formation of a blood clot within the blood vessels of the brain. This can occur due to a variety of factors, including injury, infection, or underlying medical conditions such as atrial fibrillation or sickle cell disease. Intracranial thrombosis can lead to a range of symptoms, including headache, seizures, weakness or numbness on one side of the body, difficulty speaking or understanding speech, and loss of consciousness. If left untreated, it can also lead to serious complications such as stroke or brain damage. Treatment for intracranial thrombosis typically involves the use of blood-thinning medications to dissolve the clot, as well as supportive care to manage symptoms and prevent further complications.
Postoperative complications are adverse events that occur after a surgical procedure. They can range from minor issues, such as bruising or discomfort, to more serious problems, such as infection, bleeding, or organ damage. Postoperative complications can occur for a variety of reasons, including surgical errors, anesthesia errors, infections, allergic reactions to medications, and underlying medical conditions. They can also be caused by factors such as poor nutrition, dehydration, and smoking. Postoperative complications can have serious consequences for patients, including prolonged hospital stays, additional surgeries, and even death. Therefore, it is important for healthcare providers to take steps to prevent postoperative complications and to promptly recognize and treat them if they do occur.
Carotid artery diseases refer to a group of conditions that affect the carotid arteries, which are the main blood vessels that supply oxygen-rich blood to the brain. These diseases can lead to a reduced blood flow to the brain, which can cause symptoms such as dizziness, weakness, and even stroke. The most common types of carotid artery diseases are carotid artery stenosis and carotid artery dissection. Carotid artery stenosis occurs when the inside of the carotid artery becomes narrowed or blocked by a buildup of plaque, which is made up of fat, cholesterol, and other substances. Carotid artery dissection occurs when the inner lining of the carotid artery is torn, which can cause a blood clot to form and block the flow of blood. Other types of carotid artery diseases include carotid artery aneurysm, carotid artery occlusion, and carotid artery inflammation. Carotid artery aneurysm occurs when a section of the carotid artery becomes weakened and bulges outwards. Carotid artery occlusion occurs when the carotid artery is completely blocked, which can cause a stroke. Carotid artery inflammation, also known as carotid artery vasculitis, is an inflammatory condition that can cause the walls of the carotid artery to become thickened and narrowed. Treatment for carotid artery diseases depends on the specific type and severity of the condition. In some cases, lifestyle changes such as quitting smoking, eating a healthy diet, and exercising regularly may be sufficient to manage the condition. In more severe cases, medications such as blood thinners or cholesterol-lowering drugs may be prescribed. In some cases, surgery or endovascular procedures may be necessary to remove plaque or repair damaged arteries.
Pancreatic elastase is a digestive enzyme that is produced by the pancreas and is responsible for breaking down proteins in the small intestine. It is a serine protease that cleaves peptide bonds in proteins, particularly those that contain the amino acids arginine and lysine. Pancreatic elastase is secreted by the pancreas into the small intestine, where it helps to break down dietary proteins into smaller peptides and amino acids that can be absorbed by the body. It also plays a role in the breakdown of certain hormones and other proteins in the body. Abnormalities in the production or function of pancreatic elastase can lead to a variety of digestive disorders, including chronic pancreatitis, cystic fibrosis, and certain types of cancer. In these conditions, the pancreas may not produce enough elastase, or the enzyme may not function properly, leading to malabsorption of nutrients and other digestive problems.
Intracranial Arteriovenous Malformations (AVMs) are abnormal connections between arteries and veins in the brain. These connections can cause blood to flow in the wrong direction, leading to high blood pressure and an increased risk of stroke, seizures, and other complications. AVMs can occur anywhere in the brain, but they are most commonly found in the brainstem, cerebellum, and temporal lobes. They can be congenital (present at birth) or acquired (developing later in life). Treatment options for AVMs include medication, radiation therapy, and surgery.
In the medical field, recurrence refers to the reappearance of a disease or condition after it has been treated or has gone into remission. Recurrence can occur in various medical conditions, including cancer, infections, and autoimmune diseases. For example, in cancer, recurrence means that the cancer has come back after it has been treated with surgery, chemotherapy, radiation therapy, or other treatments. Recurrence can occur months, years, or even decades after the initial treatment. In infections, recurrence means that the infection has returned after it has been treated with antibiotics or other medications. Recurrence can occur due to incomplete treatment, antibiotic resistance, or other factors. In autoimmune diseases, recurrence means that the symptoms of the disease return after they have been controlled with medication. Recurrence can occur due to changes in the immune system or other factors. Overall, recurrence is a significant concern for patients and healthcare providers, as it can require additional treatment and can impact the patient's quality of life.
Cerebral hemorrhage, also known as intracerebral hemorrhage, is a medical emergency that occurs when a blood vessel in the brain ruptures, causing blood to leak into the surrounding brain tissue. This can cause severe brain damage and can be life-threatening if not treated promptly. Cerebral hemorrhage is a type of stroke, which is a leading cause of disability and death worldwide. It can occur due to a variety of factors, including high blood pressure, aneurysms, brain tumors, and certain medications. Symptoms of cerebral hemorrhage can include sudden and severe headache, nausea and vomiting, confusion, loss of consciousness, weakness or numbness in the face, arms, or legs, difficulty speaking or understanding speech, and vision problems. Treatment for cerebral hemorrhage typically involves reducing blood pressure, controlling bleeding, and managing symptoms. In some cases, surgery may be necessary to remove the blood clot or repair the ruptured blood vessel. The outcome of cerebral hemorrhage depends on the severity of the bleeding, the location of the hemorrhage in the brain, and the promptness and effectiveness of treatment.
Intraoperative complications refer to any unexpected events or problems that occur during a surgical procedure. These complications can range from minor issues, such as bleeding or infection, to more serious problems, such as organ damage or death. Intraoperative complications can be caused by a variety of factors, including surgical errors, anesthesia errors, or underlying medical conditions of the patient. It is important for surgeons and other medical professionals to be aware of the potential for intraoperative complications and to take steps to prevent them whenever possible. If a complication does occur, it is important to address it promptly and appropriately to minimize the risk of further harm to the patient.
In the medical field, "polyvinyls" typically refers to a group of synthetic polymers that are derived from vinyl chloride. These polymers are commonly used in medical applications due to their versatility, durability, and low cost. One common example of a polyvinyl used in medicine is polyvinyl chloride (PVC), which is a plastic material that is widely used in medical devices such as blood bags, intravenous tubing, and medical equipment. PVC is also used in the production of medical clothing, such as gowns and masks. Another example of a polyvinyl used in medicine is polyvinyl acetate (PVA), which is a water-soluble polymer that is used in the production of medical adhesives, coatings, and films. PVA is also used in the production of medical textiles, such as surgical drapes and wound dressings. While polyvinyls have many useful properties in medical applications, they can also pose some risks. For example, PVC has been linked to the release of harmful chemicals, such as phthalates and dioxins, which can have negative effects on human health. As a result, there is ongoing research and development to find alternative materials that are safer and more sustainable for use in medical applications.
Loeys-Dietz syndrome (LDS) is a rare genetic disorder that affects connective tissue, blood vessels, and the skull. It is caused by mutations in the TGFBR1 or TGFBR2 genes, which are involved in the production of proteins that regulate the growth and development of connective tissue. People with LDS typically have a characteristic facial appearance, including a prominent forehead, down-slanting eyes, and a thin upper lip. They may also have cardiovascular abnormalities, such as aneurysms or dissections of the aorta, as well as skeletal abnormalities, such as scoliosis or kyphosis. LDS is inherited in an autosomal dominant pattern, which means that a person only needs to inherit one copy of the mutated gene from one parent to develop the disorder. The severity of symptoms can vary widely among affected individuals, and treatment is typically focused on managing the specific symptoms that a person is experiencing.
Vasospasm, intracranial refers to a condition in which the blood vessels in the brain constrict or narrow, leading to a decrease in blood flow to the brain. This can occur as a complication of subarachnoid hemorrhage (SAH), which is a type of bleeding in the space surrounding the brain. Vasospasm can also occur as a result of other conditions, such as head injury, stroke, or infection. The constriction of the blood vessels can lead to a decrease in the amount of oxygen and nutrients that reach the brain, which can cause damage to brain tissue and lead to a range of symptoms, including headache, confusion, seizures, and even coma or death. Vasospasm is typically treated with medications that help to relax the blood vessels and improve blood flow to the brain. In severe cases, surgery may be necessary to treat the underlying cause of the vasospasm and prevent further damage to the brain.
Marfan syndrome is a genetic disorder that affects the connective tissue in the body. It is caused by a mutation in the FBN1 gene, which provides instructions for making a protein called fibrillin-1. This protein is essential for the normal development and maintenance of connective tissue, which is found throughout the body and provides support and structure to organs and tissues. People with Marfan syndrome may have a variety of symptoms, including: - Tall stature and long limbs - Thin, delicate skin that bruises easily - Long, thin fingers and toes - Vision problems, such as nearsightedness or astigmatism - Heart problems, such as mitral valve prolapse or aortic aneurysm - Lung problems, such as scoliosis or chronic obstructive pulmonary disease (COPD) - Skeletal problems, such as kyphosis or scoliosis Marfan syndrome is usually diagnosed based on a combination of symptoms, family history, and genetic testing. There is no cure for Marfan syndrome, but treatment can help manage symptoms and prevent complications. This may include medications to treat heart problems, surgery to repair or replace damaged organs, and physical therapy to improve mobility and strength.
Traumatic brain hemorrhage (TBH) is a type of brain injury that occurs when a blood vessel in the brain is ruptured, causing bleeding inside the skull. This can happen as a result of a blow to the head, such as a fall, car accident, or sports injury. TBH can be classified into two types: acute and chronic. Acute TBH occurs suddenly and is often associated with a severe head injury, while chronic TBH develops over time and may be caused by a long-term injury or a medical condition such as hypertension or aneurysm. Symptoms of TBH can vary depending on the location and severity of the bleeding. Common symptoms include headache, nausea and vomiting, confusion, seizures, loss of consciousness, and changes in behavior or personality. Treatment for TBH depends on the severity of the injury and the underlying cause. In some cases, surgery may be necessary to remove the blood clot or repair the damaged blood vessel. Medications may also be used to control bleeding, reduce swelling, and prevent infection. In severe cases, hospitalization and intensive care may be necessary.
Intracranial embolism is a medical condition in which a blood clot or other foreign material travels through the bloodstream and lodges in a blood vessel within the brain. This can cause a blockage in the flow of blood to the brain, leading to a lack of oxygen and nutrients to the brain cells. The resulting damage can cause a range of symptoms, including headache, confusion, seizures, and loss of consciousness. In severe cases, intracranial embolism can lead to permanent brain damage or even death. It is a medical emergency that requires prompt diagnosis and treatment.
Polycystic kidney, autosomal dominant (PKD1) is a genetic disorder that affects the kidneys and is characterized by the development of multiple cysts (fluid-filled sacs) in the kidneys. It is inherited in an autosomal dominant pattern, which means that a person only needs to inherit one copy of the mutated gene from one parent to develop the condition. PKD1 is caused by mutations in the PKD1 gene, which provides instructions for making a protein called polycystin-1. This protein is essential for the normal development and function of the kidneys. Mutations in the PKD1 gene can lead to the formation of cysts in the kidneys, which can cause the kidneys to become enlarged and dysfunctional over time. PKD1 can also affect other organs, including the liver, pancreas, and brain. Symptoms of PKD1 may include abdominal pain, blood in the urine, high blood pressure, and kidney failure. Treatment for PKD1 may include medications to manage symptoms and prevent complications, as well as kidney transplantation in severe cases.
Carotid artery, internal, dissection is a medical condition in which a tear or a split occurs in the inner lining of the carotid artery, which is a major blood vessel in the neck that supplies blood to the brain. This tear can cause a blood clot to form, which can block blood flow to the brain and lead to a stroke. The most common cause of carotid artery dissection is a blow to the neck, such as a fall or a sports injury. Other risk factors include smoking, high blood pressure, and a family history of the condition. Treatment for carotid artery dissection may include medication to dissolve the blood clot, surgery to remove the clot, or angioplasty to open up the artery.
Foreign-body migration is a medical condition in which a foreign object, such as a piece of food, a splinter, or a surgical implant, moves from its original location in the body to a new location. This can occur due to various factors, including the body's natural movements, changes in the shape or size of the foreign object, or the body's immune response to the object. Foreign-body migration can be a serious medical problem, as it can cause inflammation, infection, or damage to surrounding tissues. In some cases, the foreign object may become trapped in a narrow passage or obstruct a vital organ, leading to serious complications. Treatment for foreign-body migration depends on the location and size of the object, as well as the severity of any associated complications. In some cases, the object may be able to be removed through minimally invasive procedures, such as endoscopy or laparoscopy. In more severe cases, surgery may be necessary to remove the object and repair any damage caused by its migration.
Elastin is a protein found in connective tissues throughout the body, including skin, blood vessels, lungs, and the digestive tract. It is responsible for the elasticity and flexibility of these tissues, allowing them to stretch and return to their original shape. In the medical field, elastin is important for maintaining the integrity and function of various organs and systems. For example, in the skin, elastin helps to keep the skin supple and resistant to wrinkles. In the lungs, elastin helps to maintain the elasticity of the airways, allowing them to expand and contract during breathing. In the blood vessels, elastin helps to maintain the strength and flexibility of the vessel walls, allowing blood to flow smoothly. Elastin is also important for wound healing, as it helps to repair damaged tissue and restore its elasticity. In some medical conditions, such as Ehlers-Danlos syndrome, there is a deficiency or abnormality in elastin production, leading to connective tissue disorders and other health problems.
Polyarteritis nodosa (PAN) is a rare autoimmune disorder that involves inflammation of small and medium-sized blood vessels (arterioles) throughout the body. It is characterized by the formation of nodules or masses of inflamed tissue in the walls of the affected arteries, which can lead to damage to the blood vessels and the organs they supply. PAN can affect any part of the body, but it most commonly affects the kidneys, stomach, and nervous system. The symptoms of PAN can vary depending on which organs are affected, but they may include fever, fatigue, joint pain, abdominal pain, and skin rashes. PAN is usually diagnosed through a combination of physical examination, blood tests, imaging studies, and a biopsy of the affected tissue. Treatment for PAN typically involves the use of high-dose corticosteroids and other immunosuppressive medications to reduce inflammation and prevent further damage to the blood vessels and organs. In some cases, surgery may be necessary to repair or replace damaged blood vessels.
Hematoma, Subdural, Acute is a medical condition that refers to the accumulation of blood between the dura mater (outermost layer of the brain) and the arachnoid mater (middle layer of the brain). It is an acute condition, meaning it develops suddenly and requires prompt medical attention. Acute subdural hematoma can be caused by a head injury, such as a blow to the head, or by bleeding from a blood vessel in the brain. Symptoms of acute subdural hematoma may include headache, nausea, vomiting, confusion, seizures, and loss of consciousness. Treatment for acute subdural hematoma typically involves surgery to remove the blood clot and relieve pressure on the brain. In some cases, medication may be used to control symptoms or prevent further bleeding.，，。
Basal Ganglia Hemorrhage is a medical condition that occurs when there is bleeding in the basal ganglia, a group of small, deep-seated structures in the brain that are responsible for controlling movement, emotions, and learning. This type of hemorrhage is usually caused by a rupture of small blood vessels in the brain, which can be the result of high blood pressure, head trauma, or a brain tumor. Symptoms of Basal Ganglia Hemorrhage may include headache, nausea, vomiting, confusion, difficulty speaking or understanding speech, weakness or numbness in the face or limbs, and difficulty with coordination and balance. Treatment for Basal Ganglia Hemorrhage may include medications to control high blood pressure, surgery to remove the blood clot, and rehabilitation to help with recovery.
Doxycycline is an antibiotic medication that is used to treat a variety of bacterial infections, including acne, chlamydia, gonorrhea, and respiratory tract infections. It is also used to prevent and treat malaria, as well as to treat certain types of anthrax. Doxycycline works by inhibiting the growth of bacteria, and it is typically taken orally in the form of tablets or capsules. It is important to follow the dosing instructions provided by your healthcare provider and to complete the full course of treatment, even if you start to feel better before the medication is finished. Doxycycline can cause side effects, including nausea, vomiting, diarrhea, and headache, and it may interact with other medications, so it is important to tell your healthcare provider about all of the medications you are taking before starting doxycycline.
Moyamoya disease is a rare cerebrovascular disorder that affects the blood vessels in the brain. It is characterized by the narrowing or occlusion of the internal carotid artery and its branches, which can lead to decreased blood flow to the brain. This can cause a variety of symptoms, including headaches, dizziness, seizures, and stroke. Moyamoya disease is typically diagnosed through a combination of medical history, physical examination, and imaging tests such as magnetic resonance imaging (MRI) or computed tomography (CT) scans. Treatment for Moyamoya disease may include medications to manage symptoms, surgery to improve blood flow to the brain, or a combination of both.
Oculomotor nerve diseases refer to disorders that affect the oculomotor nerve, which is responsible for controlling the movement of the eye muscles. The oculomotor nerve is the third cranial nerve and is responsible for controlling six muscles in the eye, including the superior rectus, inferior rectus, medial rectus, lateral rectus, inferior oblique, and superior oblique muscles. Oculomotor nerve diseases can be caused by a variety of factors, including trauma, infection, inflammation, tumors, and degenerative diseases. Some common oculomotor nerve diseases include: 1. Oculomotor nerve palsy: This is a condition in which the oculomotor nerve is damaged, leading to weakness or paralysis of the eye muscles. Symptoms may include drooping eyelids, double vision, and difficulty moving the eyes. 2. Myasthenia gravis: This is an autoimmune disorder that affects the muscles, including the muscles of the eye. Symptoms may include drooping eyelids, double vision, and difficulty moving the eyes. 3. Optic neuritis: This is an inflammation of the optic nerve that can cause vision loss and double vision. It can also affect the oculomotor nerve, leading to weakness or paralysis of the eye muscles. 4. Brainstem tumors: Tumors in the brainstem can compress the oculomotor nerve, leading to weakness or paralysis of the eye muscles. Symptoms may include drooping eyelids, double vision, and difficulty moving the eyes. 5. Multiple sclerosis: This is an autoimmune disorder that affects the central nervous system, including the oculomotor nerve. Symptoms may include drooping eyelids, double vision, and difficulty moving the eyes. Treatment for oculomotor nerve diseases depends on the underlying cause and may include medications, surgery, or physical therapy. It is important to seek medical attention if you experience symptoms of an oculomotor nerve disease, as early diagnosis and treatment can help prevent complications and improve outcomes.
Thromboembolism is a medical condition that occurs when a blood clot (thrombus) forms in a vein or artery and breaks off, traveling through the bloodstream to block a smaller vessel. This can cause a variety of symptoms, depending on the location and size of the clot. When a clot forms in a deep vein, it is called deep vein thrombosis (DVT). If the clot breaks off and travels through the bloodstream to block a smaller vessel, it is called an embolism. An embolism can block blood flow to organs or tissues, leading to serious complications such as stroke, heart attack, or organ damage. Thromboembolism can be caused by a variety of factors, including prolonged immobility, surgery, pregnancy, certain medications, and underlying medical conditions such as cancer or blood disorders. It is a serious medical condition that requires prompt diagnosis and treatment to prevent complications.
An endoleak is a type of leakage that occurs within a blood vessel after a procedure called endovascular aneurysm repair (EVAR). EVAR is a minimally invasive surgical procedure used to treat abdominal aortic aneurysms (AAAs), which are bulges in the wall of the aorta, the largest artery in the body. During EVAR, a stent graft is placed inside the aorta to reinforce the weakened area and prevent the aneurysm from expanding further. However, sometimes blood can leak through small tears or holes in the stent graft, which can lead to an endoleak. There are several types of endoleaks, including type I, type II, and type III. Type I endoleaks occur when blood leaks through the stent graft into the aneurysm sac, while type II endoleaks occur when blood leaks through the stent graft into the aorta. Type III endoleaks are the most serious and occur when blood leaks through a tear in the aorta into the peritoneal cavity, which is the space that surrounds the abdominal organs. Endoleaks can be detected using imaging tests such as computed tomography (CT) scans or magnetic resonance imaging (MRI). Treatment options for endoleaks depend on the type and severity of the leak, but may include additional procedures to repair the leak or medications to reduce blood flow to the aneurysm.
Aminocaproates are a class of amino acid derivatives that are commonly used in the medical field as chelating agents. They are used to treat heavy metal poisoning, such as lead poisoning, by binding to the heavy metal ions and facilitating their elimination from the body. Aminocaproates are also used in the treatment of certain types of cancer, such as multiple myeloma, by disrupting the growth and proliferation of cancer cells. They are typically administered intravenously and can cause side effects such as nausea, vomiting, and allergic reactions.
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- The cerebral vasculature and, moreover, cerebral aneurysms are a complex biological system. (medscape.com)
- Medical therapy of cerebral aneurysms involves general supportive measures and prevention of complications for individuals who are in the periprocedural period or are poor surgical candidates. (medscape.com)
- More recently, application of diffusion-weighted MRI has demonstrated silent thromboembolic events associated with endovascular treatment of unruptured cerebral aneurysms. (medscape.com)
- We selected articles assessing the role of endothelialization in flow-diverter treatment of cerebral aneurysms, including both preclinical and clinical studies. (ajnr.org)
- Intracranial infectious aneurysms, or mycotic aneurysms, are rare infectious cerebrovascular lesions which arise through microbial infection of the cerebral arterial wall. (neurosurgery-blog.com)
- We undertook a comprehensive literature search using the OVID gateway of the MEDLINE database (1950-2009) using the following keywords (singly and in combination): "infectious," "mycotic," "cerebral aneurysm," and "intracranial aneurysm. (neurosurgery-blog.com)
- Prospective international cohort trials have suggested that incidental cerebral aneurysms with diameters less than 10 mm are unlikely to rupture. (edu.au)
- Consequently, small ruptured cerebral aneurysms should rarely be seen in clinical practice. (edu.au)
- To verify this theory, dimensions and locations of ruptured cerebral aneurysms were analyzed across the state of Tasmania, Australia. (edu.au)
- We retrospectively reviewed medical records and diagnostic tests of all patients admitted with ruptured cerebral aneurysms during a 5-year interval. (edu.au)
- Results A total of 131 ruptured cerebral aneurysms were encountered and treated by microsurgical clipping ( n = 59) or endovascular techniques ( n = 72). (edu.au)
- Endovascular therapies include embolotherapy (see images below), the goal of which is occlusion of abnormal blood vessels (eg, vascular malformations, aneurysms, vascular tumors), and cerebral revascularization , performed with the goal of reopening occluded or narrowed normal vessels. (medscape.com)
- NIOSH investigator concluded that the AC's death from the NIOSH Fire Fighter Fatality Investigation was due to rupture of a cerebral aneurysm, possibly Team traveled to Texas to conduct an on-site investi- triggered by the physical exertion associated with fi re gation of the incident. (cdc.gov)
- In this study, using fluid-structure interaction (FSI), 3-dimensional blood flow in an aneurysm in the circle of Willis - which is located in the middle cerebral artery (MCA) - has been simulated. (karger.com)
- Brain aneurysms are focal dilations in the cerebral arteries. (msdmanuals.com)
- Most brain aneurysms occur along the middle or anterior cerebral arteries or the communicating branches of the circle of Willis, particularly at arterial bifurcations. (msdmanuals.com)
- A cerebral aneurysm (also known as an intracranial or intracerebral aneurysm) is a weak or thin spot on a blood vessel in the brain that balloons out and fills with blood. (biacolorado.org)
- Some cerebral aneurysms, particularly those that are very small, do not bleed or cause other problems. (biacolorado.org)
- Cerebral aneurysms can occur anywhere in the brain, but most are located along a loop of arteries that run between the underside of the brain and the base of the skull. (biacolorado.org)
- Dr. Etminan said, "This gives the reader a good impression on current opinion on the assessment of aneurysms, especially what factors cerebrovascular specialists consider to increase risk of rupture or risk of treatment and where areas of uncertainty are. (medscape.com)
- One of the largest prospective studies to evaluate the risk for rupture previously found that aneurysms less than 7 mm in diameter have a very low risk for rupture. (medscape.com)
- However, small aneurysms are often found as a cause in the setting of subarachnoid hemorrhage (SAH), so additional factors might put an aneurysm at risk for rupture. (medscape.com)
- On the importance of life expectancy, Dr. Etminan explained that while the risk for rupture for some aneurysms may be low over a 5- to 10-year period, it will be difficult to estimate this risk over a 30- to 40-year period. (medscape.com)
- Our review suggests that SFD achieves comparable AOR to its contemporary, the Pipeline Embolization Device (ev3 Endovascular, Plymouth, MN, USA) but has a higher rate of higher rate of ischemic complications, aneurysm rupture and mortality. (nih.gov)
- The International Study of Unruptured Intracranial Aneurysms (ISUIA) indicated a relatively low risk of rupture in small aneurysms without history of SAH. (medscape.com)
- The presence of cigarette smoking, family history of aneurysms, polycystic kidney disease, or systemic lupus erythematosus may elevate the risk of rupture and should be considered. (medscape.com)
- Surgery may be needed to treat aneurysms that have the potential to rupture and cause bleeding within the brain. (nih.gov)
- With regard to the high amount of Von Mises stress, the risk of rupture of the aneurysm is higher in this case. (karger.com)
- both effects contribute to aneurysm rupture. (msdmanuals.com)
- Blood pressure control is important in preventing aneurysm rupture. (msdmanuals.com)
- Before rupture, aneurysms occasionally cause sentinel (warning) headaches due to painful expansion of the aneurysm or to blood leaking into the subarachnoid space. (msdmanuals.com)
- If 7 mm, asymptomatic aneurysms in the anterior circulation rarely rupture and do not warrant the risks of immediate treatment. (msdmanuals.com)
- SAD score of intracranial aneurysms for rupture risk assessment based on high-resolution vessel wall imaging. (nih.gov)
- Infectious aneurysms are friable, with an increased propensity for hemorrhage. (medscape.com)
- It may also play an important role in the occlusion of aneurysms in the acute phase of subarachnoid hemorrhage. (thejns.org)
- Bleeding in the brain (intracranial hemorrhage) may occur if an aneurysm ruptures, and it is important to identify and treat brain aneurysms early to prevent this. (rarediseases.org)
- We observed negative associations for groups containing the outcomes other aneurysm and intracranial hemorrhage. (nih.gov)
- It works on the principle of redirecting flow away from the aneurysm sac, leading to occlusion over time. (nih.gov)
- 10, use of SFD only, data on complications and aneurysm occlusion rate (AOR). (nih.gov)
- The main outcome measure, 12 month AOR, was 81.8% with complete occlusion in 216 out of 264 aneurysms. (nih.gov)
- Aneurysm occlusion via flow diversion has traditionally been proposed to occur by 2 predominant overarching processes: 1) intra-aneurysmal thrombosis following device-related disruption of blood flow, and 2) provision of a scaffold for endothelial cell growth at the aneurysmal neck by the device itself. (ajnr.org)
- Fibromuscular dysplasia includes a heterogenous group of nonatherosclerotic, noninflammatory arterial changes, causing some degree of vascular stenosis, occlusion, or aneurysm. (merckmanuals.com)
- The underlying mechanism of action of flow diverters is believed to be the induction of aneurysm thrombosis and simultaneous endothelial cell growth along the device struts, thereby facilitating aneurysm exclusion from the circulation. (ajnr.org)
- Considerable thrombosis of the aneurysm (70% to 100%) was achieved in all 15 patients, and preservation of the parent artery was obtained in 14. (thejns.org)
Less than 10 mm1
- Some investigators have advocated endovascular or surgical treatment of all aneurysms less than 10 mm if age is less than 50 years, in the absence of contraindications. (medscape.com)
Location of the aneurysm1
- The literature supports the administration of antibiotics in conjunction with surgical or endovascular intervention depending on the character and location of the aneurysm, as well as the clinical status of the patient. (neurosurgery-blog.com)
- If I had a young patient who was a smoker and had hypertension and a 4-mm aneurysm, my advice may be different than if it was a 75-year-old patient who didn't have those risk factors and aneurysm of the same size. (medscape.com)
- Prior to definitive aneurysm treatment, medical approaches involve control of hypertension, administration of calcium channel blockers, and prevention of seizures. (medscape.com)
- Other common symptoms include hypertension, liver cysts and intracranial aneurysms. (nih.gov)
- Affected individuals also suffer from other complications such as hypertension, cyst infections, abdominal pain, and have an increased risk of intracranial aneurysms. (nih.gov)
- Although embolotherapy has been practiced for approximately 40 years, application of this therapy for definitive or preoperative adjunctive management of aneurysms, vascular malformations, and vascular tumors continues to evolve. (medscape.com)
- Fifteen patients with high-risk intracranial saccular aneurysms were treated using electrolytically detachable coils introduced via an endovascular approach. (thejns.org)
- It is believed that this new technology is a viable alternative in the management of patients with high-risk intracranial saccular aneurysms. (thejns.org)
- 1 - 7 , 1991 Guglielmi G, Viñuela F, Sepetka I, et al: Electrothrombosis of saccular aneurysms via endovascular approach. (thejns.org)
- Several different flexible self-expanding stents were introduced over the last years and clinically used for the treatment of those complex intracranial aneurysms. (en.life)
- Only a few studies have described the initial clinical experiences and follow-up results with Acclino stents in the treatment of intracranial aneurysms in small cohorts. (en.life)
- We identified 27 published clinical series describing a total of 287 patients in the English literature that presented demographic and clinical data regarding presentation, treatment, and outcome of patients with mycotic aneurysms. (neurosurgery-blog.com)
- We follow by presenting a comprehensive review of mycotic aneurysms, highlighting current treatment paradigms. (neurosurgery-blog.com)
- Mycotic aneurysms comprise an important subtype of potentially life-threatening cerebrovascular lesions, and further prospective studies are warranted to define outcome following both conservative and surgical or endovascular treatment. (neurosurgery-blog.com)
- Occasionally, septic emboli cause mycotic aneurysms. (msdmanuals.com)
- Mycotic aneurysms usually develop distal to the first bifurcation of the arterial branches of the circle of Willis. (msdmanuals.com)
- Headaches are believed to be associated with constriction and dilation of intracranial and extracranial arteries. (womens-health-club.com)
- The signs and/or symptoms that a person with FMD may experience depend on the arteries affected and whether there is narrowing, tears, or aneurysms within them. (rarediseases.org)
- People with carotid FMD have a higher risk for aneurysms of the arteries in the brain (intracranial aneurysms). (rarediseases.org)
- Fibromuscular dysplasia may affect the renal arteries (in 60 to 75% of patients), carotid and intracranial arteries (25 to 30% of patients), intra-abdominal arteries (9% of patients), or external iliac arteries (5% of patients). (merckmanuals.com)
- He pointed out that because patients are undergoing cranial imaging more frequently for symptoms such as headache and dizziness, unruptured intracranial aneurysms, which occur in about 2% to 3% of the population, are being found more often. (medscape.com)
- Many aneurysms are asymptomatic, but a few, usually large or growing aneurysms, cause symptoms by compressing adjacent structures. (msdmanuals.com)
- Although all patients with ruptured or unruptured aneurysms should be evaluated for endovascular therapy, not all are best served by this therapy. (medscape.com)
- Intracranial aneurysm outcomes have been improving for both ruptured and unruptured cases, apparently due to increasing use of endovascular therapy and other improvements, one neurovascular center reported. (medpagetoday.com)
- Recent guidelines and an evidence-based systematic review of the literature have formulated recommendations for the care of patients with unruptured intracranial aneurysms, principally based on age, history, and aneurysm size. (medscape.com)
- Although extensive attention has been paid to the role of altered cerebrovascular hemodynamics using computational fluid dynamics analyses, relatively less emphasis has been placed on the role of the vascular endothelium in promoting aneurysm healing. (ajnr.org)
- In the recent years various simulation challenges have been organized in order to check the applicability of the computational hemodynamics for intracranial aneurysms. (cfd-online.com)
- In rare cases, FMD-related aneurysms can burst and bleed into the brain, causing stroke, permanent nerve damage, or death. (nih.gov)
- NIOSH contacted the affected facility death certifi cate (completed by the attending physi- on April 10, 2006, to obtain further information, and cian) listed "brain death due to brain aneurysm" as on May 26, 2006, to initiate the investigation. (cdc.gov)
- In the United States, brain aneurysms occur in 3 to 5% of people. (msdmanuals.com)
- Brain aneurysms can occur at any age but are most common among people aged 30 to 60 years. (msdmanuals.com)
- In the years after a key trial supporting endovascular coiling of ruptured brain aneurysms, survivors were substantially more likely to have a good neurological outcome with no assistance needed for everyday life, Christopher S. Ogilvy, MD, and colleagues reported from their 2,522-patient experience at Massachusetts General Hospital in Boston. (medpagetoday.com)
- Brain aneurysms can occur at any age but are most common among. (merckmanuals.com)
- A brain tumor or intracranial neoplasm occurs when abnormal cells form within the brain. (biacolorado.org)
- The bulging aneurysm can put pressure on a nerve or surrounding brain tissue. (biacolorado.org)
- Brain Aneurysm Foundation - The mission of the Brain Aneurysm Foundation is to provide support networks and educational resources to raise public awareness regarding early detection and treatment of brain aneurysms. (biacolorado.org)
- Regression or evolution of these aneurysms is monitored with serial angiography. (medscape.com)
- Aneurysm location, maximum size, dome-to-neck ratio, volume, and presence of daughter sacs were determined by preoperative digital subtraction angiography or computed tomography angiography. (edu.au)
- Diagnosis of aneurysms requires angiography, CT angiography, or magnetic resonance angiography. (msdmanuals.com)
- Catheter-based digital subtraction angiography (DSA) is the gold standard for diagnosing aneurysms. (msdmanuals.com)
- There is an increasing need to reliably counsel patients with unruptured aneurysms on the best course of action," he said. (medscape.com)
- Eight studies with 285 patients and 317 intracranial aneurysms were included. (nih.gov)
- In consequence, it seems important to identify those patients with small but vulnerable unruptured aneurysms before conservative management is considered. (edu.au)
- Flow diversion has revolutionized the treatment of select intracranial aneurysms, representing both a safe and efficacious alternative to open microsurgery and other endovascular modalities. (ajnr.org)
- In terms of angiographic distribution, 86.8% of aneurysms were located in the anterior circulation and 13.2% in the posterior circulation. (nih.gov)
- Asymptomatic aneurysms greater than 10 mm should also be considered for treatment, accounting for age, coexisting medical conditions, and relative risks for treatment. (medscape.com)
Clinical status of the patient1
- Treatment decisions should be based on the clinical status of the patient, vascular anatomy of the aneurysm, and surgical or endovascular considerations. (medscape.com)
- A ruptured intracranial aneurysm causes intracranial bleeding and is considered very dangerous. (medlineplus.gov)
- Is there any seasonal influence in spontaneous bleeding of intracranial aneurysm and and/or AVM in Istanbul? (smw.ch)
- The most common cause of spontaneous bleeding is a ruptured aneurysm. (msdmanuals.com)
- 17. Bleeding intracranial aneurysm? (nih.gov)
- If caused by intracranial bleeding. (womens-health-club.com)
- Large ruptured aneurysm before embolization (A) and after embolization (B, C) embolization with Guglielmi detachable coils. (medscape.com)
- Balloon embolization of a large distal basilar artery aneurysm. (thejns.org)
- Balt Extrusion, Montmorency, France) is a flow diverting stent used in the endovascular treatment of intracranial aneurysms. (nih.gov)
- A literature search for English language articles were conducted on PubMed, Medline and EMBASE for articles on the treatment of intracranial aneurysms with the SILK flow diverter. (nih.gov)
- Use of flow diverters for the treatment of intracranial aneurysm with complex morphologies has gained in popularity over the last few years. (nih.gov)
- Following surgical or endovascular aneurysm treatment, blood pressure is maintained at higher levels to diminish complications associated with vasospasm. (medscape.com)
- Considerable surgical mortality and morbidity rates at 1 year (as high as 3.8% and 15.7%, respectively) have been demonstrated in preventive treatment of unruptured aneurysms. (medscape.com)
- Future studies in the management of unruptured intracranial aneurysms may systematically account for the evolving technology of advanced endovascular approaches, detailed aneurysm morphology, novel neuroimaging correlates, ethnic and geographical variation, neurocognitive impairment following endovascular or surgical treatment, and quality-of-life issues. (medscape.com)
- The stent-assisted coiling technique was developed to enable endovascular treatment of bifurcation aneurysms and aneurysms with an unfavourable dome-to-neck ratio, previously uncoilable. (en.life)
- The ongoing evolution of these stent system with improved features and a broader spectrum of stent diameters further increased the technical possibilities of minimally invasive intracranial aneurysm treatment. (en.life)
- Multicenter Study for the Treatment of Sidewall versus Bifurcation Intracranial Aneurysms with Use of Woven EndoBridge (WEB). (austin.org.au)
- Treatment depends on the location and includes angioplasty, bypass surgery, or aneurysm repair. (merckmanuals.com)
- The anatomical characterization and morphology of unruptured aneurysms are not readily standardized, however. (medscape.com)
Computational fluid dy1
- Variability of computational fluid dynamics solutions for pressure and flow in a giant aneurysm: the ASME 2012 Summer Bioengineering Conference CFD Challenge. (cfd-online.com)
- In selecting appropriate therapy, referring and interventional physicians should consider the configuration of the aneurysm and its neck, the location(s) and number of aneurysms, and the patient's preference and overall physical condition (eg, ability to tolerate anesthesia and surgery). (medscape.com)
- An angiogram can detect the degree of narrowing or obstruction of the artery and identify changes such as a tear (dissection) or weak area (aneurysm) in the vessel wall. (nih.gov)
- The purpose of this study is to evaluate the effect of a partly blocked vessel on an aneurysm. (karger.com)
- in the second case, modeling is performed for an ideal geometry of the aneurysm in the MCA with a partly blocked vessel. (karger.com)
- So, the risk of growth of the aneurysm is higher in cases with a partly blocked vessel. (karger.com)
- Among some individuals with FMD, there is a family history of other vascular problems, such as blood vessel aneurysms. (rarediseases.org)
- 10% are due to underlying intracranial, systemic or psychological disorders. (womens-health-club.com)
- The natural history of unruptured intracranial aneurysms remains uncertain and especially indications for prophylactic aneurysm repair are somewhat controversial," cerebrovascular surgeon and lead author Nima Etminan, MD, Department of Neurosurgery, Medical Faculty Heinrich-Heine-University, Düsseldorf, Germany, explained to Medscape Medical News . (medscape.com)
- the various factors were then rated for their individual importance regarding the assessment of a patient with an unruptured aneurysm. (medscape.com)
- Additionally, the report provides insight on the Peripheral Aneurysms market share by segments, along with assessment of market share by regions, the qualitative and quantitative (USD million, 2019-2027) data will be provided for all the segment in the scope. (marketresearch.com)
- Assessment of Key 12-15 Players operating in the Peripheral Aneurysms market will be covered in-depth in the report comprising of company overview, financial overview, product overview and company share analysis of key 3-5 players. (marketresearch.com)
- We analysed the safety and effectiveness and evaluated the long-term results of 57 complex intracranial aneurysms treated with these stent systems. (en.life)
- Basically we are advising clinicians that factors beyond aneurysm size and location should be considered in making a decision, and even some small aneurysms require consideration of aneurysm repair. (medscape.com)
- As for the aneurysm size, 37.9% were classed as small, 44.4% as large and 17.7% as giant. (nih.gov)
- Despite findings from prospective international cohort trials, small ruptured intracranial aneurysms are common in clinical practice. (edu.au)
- sometimes they have one or more small, thin-walled, outpouchings (berry aneurysm). (msdmanuals.com)
- The management of unruptured intracranial aneurysms is highly controversial. (medscape.com)
- If a mycotic aneurysm is suspected, bacterial and fungal blood cultures should be done. (msdmanuals.com)
- Among endovascular therapies, embolization of aneurysms (see image below) is one of the principal procedures. (medscape.com)