Intestinal Atresia
Gastroschisis
Biliary Atresia
Follicular Atresia
Duodenal Obstruction
Esophageal Atresia
Congenital hernia of the abdominal wall: a differential diagnosis of fetal abdominal wall defects. (1/66)
A 28-year-old woman was referred at 33 weeks of gestation with suspected fetal intestinal atresia. Sonography showed a large extra-abdominal mass on the right of the normal umbilical cord insertion. Following Cesarean section at 36 weeks and immediate surgical treatment, the malformation was not definable either as an omphalocele or as gastroschisis. This reported case involves a previously undocumented malformation of the fetal abdominal wall described as a 'hernia' of the fetal abdominal wall. (+info)Bilious vomiting in the newborn: rapid diagnosis of intestinal obstruction. (2/66)
Bilious vomiting in newborns is an urgent condition that requires the immediate involvement of a team of pediatric surgeons and neonatologists for perioperative management. However, initial detection, evaluation and treatment are often performed by nurses, family physicians and general pediatricians. Bilious vomiting, with or without abdominal distention, is an initial sign of intestinal obstruction in newborns. A naso- or orogastric tube should be placed immediately to decompress the stomach. Physical examination should be followed by plain abdominal films. Dilated bowel loops and air-fluid levels suggest surgical obstruction. Contrast radiography may be required. Duodenal atresia, midgut malrotation and volvulus, jejunoileal atresia, meconium ileus and necrotizing enterocolitis are the most common causes of neonatal intestinal obstruction. (+info)Meconium peritonitis: prenatal diagnosis and postnatal management--a case report. (3/66)
The management of a case of antenatally diagnosed meconium peritonitis (MP) due to intrauterine intestinal perforation secondary to bowel atresia is reported. The literature is reviewed with reference to the significance and outcome of antenatally diagnosed MP. (+info)40 years' review of intestinal atresia. (4/66)
OBJECTIVE: To analyze the 40 years' experience of intestinal atresia and to introduce a new design of long-oblique anastomosis for disproportional loops of the intestine. METHODS: A total of 449 cases of congenital atresia of the small intestine were classified into three groups according to the embryopathology: high group (145 cases), including duodenal and high jejunal atresia; middle group (288), including ileo-jejunal atresia; and low group (16), including terminal ileal atresia. To analyze the survival rate and mode of treatment, we assigned the cases into 3 groups according to the year of admission: 1) 1956-1969 (173 cases), under the general pediatric surgical care; 2) 1970-1985 (147), under the specialty neonatal surgical care; and 3) 1986-1996 (129), with additional use of total parenteral nutrition. RESULTS: The ileojejunal atresia group (middle group) had the highest mortality rate (47.6%). The overall mortality rate decreased as the time went by, dropping from 64.7% in the early years down to 18.6% in the recent years, and no hospital death occurred in the recent couple of years. CONCLUSION: Besides the improvement of neonatal surgical techniques, selecting a proper surgical procedure according to the embryopathology is essential to the reduction of mortality. The long-oblique anastomosis is particularly acceptable in China at present for marked disproportional loops. (+info)Maternal medication use and risks of gastroschisis and small intestinal atresia. (5/66)
Gastroschisis and small intestinal atresia (SIA) are birth defects that are thought to arise from vascular disruption of fetal mesenteric vessels. Previous studies of gastroschisis have suggested that risk is increased for maternal use of vasoactive over-the-counter medications, including specific analgesics and decongestants. This retrospective study evaluated the relation between maternal use of cough/cold/analgesic medications and risks of gastroschisis and SIA. From 1995 to 1999, the mothers of 206 gastroschisis cases, 126 SIA cases, and 798 controls in the United States and Canada were interviewed about medication use and illnesses. Risks of gastroschisis were elevated for use of aspirin (odds ratio = 2.7, 95% confidence interval: 1.2, 5.9), pseudoephedrine (odds ratio = 1.8, 95% confidence interval: 1.0, 3.2), acetaminophen (odds ratio = 1.5, 95% confidence interval: 1.1, 2.2), and pseudoephedrine combined with acetaminophen (odds ratio = 4.2, 95% confidence interval: 1.9, 9.2). Risks of SIA were increased for any use of pseudoephedrine (odds ratio = 2.0, 95% confidence interval: 1.0, 4.0) and for use of pseudoephedrine in combination with acetaminophen (odds ratio = 3.0, 95% confidence interval: 1.1, 8.0). Reported fever, upper respiratory infection, and allergy were not associated with risks of either defect. These findings add more evidence that aspirin use in early pregnancy increases risk of gastroschisis. Although pseudoephedrine has previously been shown to increase gastroschisis risk, findings of this study raise questions about interactions between medications and possible confounding by underlying illness. (+info)Donor immune reconstitution after liver-small bowel transplantation for multiple intestinal atresia with immunodeficiency. (6/66)
The syndrome of multiple intestinal atresia with immunodeficiency is a rare, invariably fatal congenital disorder. At 16 months of age, a child with this syndrome underwent liver-small bowel transplantation from a 1-of-6 HLA-matched donor. He acquired full enteral tolerance and normal liver function and has never shown evidence of allograft rejection. After mild graft-versus-host disease developed, studies revealed that more than 99% of his CD3(+) lymphocytes and 50% of his CD19(+) lymphocytes were of donor origin, whereas granulocytes and monocytes remained of recipient origin. He synthesizes polyclonal immunoglobulin G (IgG), IgA, and IgM and has developed antibodies to cytomegalovirus (CMV) and parainfluenza 3. His T lymphocytes are predominately CD3(+)CD4(-)CD8(-) with T-cell receptor gammadelta heterodimers and CD3(+)CD4(-)CD8(+) with CD8alphaalpha homodimers, populations consistent with an intraepithelial lymphocyte phenotypic profile. We postulate that he has engrafted a donor intestine-derived immune system and is incapable of rejecting his engrafted organs. (+info)Complicated intestinal atresias. (7/66)
In this group of 45 intestinal atresia patients (duodenum, 16; jejunum, 24; ileum five) at the University of Mississippi Medical Center, individual hospitalizations ranged up to 245 days. Twelve patients required multiple operations, and the overall mortality rate was 22% (ten patients). While the patients with duodenal atresia had the greatest incidence of other congenital anomalies, including Down's syndrome, the patients with jejunal atresia presented with the most challenging surgical problems. Of the 24 jejunal atresia patients, only three had a single, simple area of obstruction. The remainder were complicated by other gastrointestinal lesions (five patients), by multiple areas of atresia (seven patients) including those in one surviving patient with 22 separate atretic segments, and by the Christmas tree deformity (nine patients). Intraoperative management of the complicated atresia should include: 1) grouping of multiple atresias during resection, 2) adequate resection of the dilated proximal atonic loop, 3) end-to-end anastomoses, 4) avoidance of intraluminal catheters, 5) additional resection of a segment of the distal loop in the Christmas tree deformity and 6) consideration of the shish kebab technique for multiple atretic webs. Postoperative management should involve early intravenous nutrition and repeated exploration for continued obstruction. (+info)Congenital jejunal and ileal atresia: natural prenatal sonographic history and association with neonatal outcome. (8/66)
OBJECTIVE: The purpose of this study was to describe the prenatal sonographic features and natural course of congenital jejunal and ileal atresia and correlate the findings with neonatal outcomes. METHODS: We identified all neonates with surgically confirmed jejunal or ileal atresia that had prenatal sonography and neonatal surgery in our center from January 1, 1995, to April 1, 2005. Sonography reports and images were reviewed, without knowledge of neonatal outcomes, for features of intestinal obstruction. Obstetric and neonatal outcomes were evaluated. RESULTS: Fifteen (60%) of 25 offspring with atresias (10 jejunal, 4 ileal, and 1 jejunoileal) had sonography, of which 13 (86.6%) had features of atresia. Findings, number of affected fetuses, and gestational age at recognition included fetal echogenic bowel (n = 8), mean +/- SD, 21.3 +/- 3.8 weeks (range, 17.7-28.4 weeks); enlarged stomach (n = 5), 27.5 +/- 5.0 weeks (range, 22.0-34.3 weeks); dilated bowel (n = 13), 27.8 +/- 5.8 weeks (range, 18.3-35.9 weeks); and polyhydramnios (n = 6), 33.3 +/- 1.7 weeks (range, 31.0-35.6 weeks). No fetus with ileal atresia had an enlarged stomach or polyhydramnios. Delivery occurred at a mean of 34.7 +/- 3.6 weeks, with 9 (60%) cesarean deliveries. Neonatal outcomes of age at surgery, neonatal intensive care unit days, hospital days, total parenteral nutrition days, and death were similar whether or not fetal echogenic bowel, enlarged stomach, dilated bowel, or polyhydramnios was present. Likewise, these outcomes did not vary by type of atresia or time of diagnosis (prenatal or neonatal). CONCLUSIONS: Jejunal and ileal atresia have specific sonographic patterns allowing specific prenatal diagnoses in most affected fetuses. Prenatal sonographic findings and time of diagnosis did not affect neonatal outcome. (+info)Intestinal atresia is a congenital condition characterized by the absence or complete closure of a portion of the intestine, preventing the passage of digested food from the stomach to the remaining part of the intestines. This results in a blockage in the digestive system, which can be life-threatening if not treated promptly after birth. The condition can occur anywhere along the small or large intestine and may affect either a single segment or multiple segments of the intestine.
There are several types of intestinal atresia, including:
1. Jejunal atresia: A closure or absence in the jejunum, a part of the small intestine located between the duodenum and ileum.
2. Ileal atresia: A closure or absence in the ileum, the lower portion of the small intestine that connects to the large intestine (cecum).
3. Colonic atresia: A closure or absence in the colon, a part of the large intestine responsible for storing and eliminating waste.
4. Duodenal atresia: A closure or absence in the duodenum, the uppermost portion of the small intestine that receives chyme (partially digested food) from the stomach.
5. Multiple atresias: When more than one segment of the intestines is affected by atresia.
The exact cause of intestinal atresia remains unclear, but it is believed to be related to disruptions in fetal development during pregnancy. Treatment typically involves surgical correction to reconnect the affected segments of the intestine and restore normal digestive function. The prognosis for infants with intestinal atresia depends on the severity and location of the atresia, as well as any associated conditions or complications.
Gastroschisis is a congenital abdominal wall defect, characterized by an opening, usually to the right of the umbilical cord, through which the abdominal organs such as the intestines protrude. It's typically not covered by a sac or membrane. The exact cause of gastroschisis is unknown, but it's thought to be related to disrupted blood flow in the area where the abdominal wall develops during pregnancy. This condition is usually detected prenatally through ultrasound and requires surgical repair shortly after birth.
Biliary atresia is a rare, progressive liver disease in infants and children, characterized by the inflammation, fibrosis, and obstruction of the bile ducts. This results in the impaired flow of bile from the liver to the intestine, leading to cholestasis (accumulation of bile in the liver), jaundice (yellowing of the skin and eyes), and eventually liver cirrhosis and failure if left untreated.
The exact cause of biliary atresia is not known, but it is believed to be a combination of genetic and environmental factors. It can occur as an isolated condition or in association with other congenital anomalies. The diagnosis of biliary atresia is typically made through imaging studies, such as ultrasound and cholangiography, and confirmed by liver biopsy.
The standard treatment for biliary atresia is a surgical procedure called the Kasai portoenterostomy, which aims to restore bile flow from the liver to the intestine. In this procedure, the damaged bile ducts are removed and replaced with a loop of intestine that is connected directly to the liver. The success of the Kasai procedure depends on several factors, including the age at diagnosis and surgery, the extent of liver damage, and the skill and experience of the surgeon.
Despite successful Kasai surgery, many children with biliary atresia will eventually develop cirrhosis and require liver transplantation. The prognosis for children with biliary atresia has improved significantly over the past few decades due to earlier diagnosis, advances in surgical techniques, and better postoperative care. However, it remains a challenging condition that requires close monitoring and multidisciplinary management by pediatric hepatologists, surgeons, and other healthcare professionals.
A newborn infant is a baby who is within the first 28 days of life. This period is also referred to as the neonatal period. Newborns require specialized care and attention due to their immature bodily systems and increased vulnerability to various health issues. They are closely monitored for signs of well-being, growth, and development during this critical time.
Follicular atresia is a physiological process that occurs in the ovary, where follicles (fluid-filled sacs containing immature eggs or oocytes) undergo degeneration and disappearance. This process begins after the primordial follicle stage and continues throughout a woman's reproductive years. At birth, a female has approximately 1 to 2 million primordial follicles, but only about 400 of these will mature and release an egg during her lifetime. The rest undergo atresia, which is a natural process that helps regulate the number of available eggs and maintain hormonal balance within the body.
The exact mechanisms that trigger follicular atresia are not fully understood, but it is believed to be influenced by various factors such as hormonal imbalances, oxidative stress, and apoptosis (programmed cell death). In some cases, accelerated or excessive follicular atresia can lead to infertility or early menopause.
Duodenal obstruction is a medical condition characterized by the blockage or impediment of the normal flow of contents through the duodenum, which is the first part of the small intestine. This blockage can be partial or complete and can be caused by various factors such as:
1. Congenital abnormalities: Duodenal atresia or stenosis, where there is a congenital absence or narrowing of a portion of the duodenum.
2. Inflammatory conditions: Duodenitis, Crohn's disease, or tumors that cause swelling and inflammation in the duodenum.
3. Mechanical obstructions: Gallstones, tumors, strictures, or adhesions (scar tissue) from previous surgeries can physically block the duodenum.
4. Neuromuscular disorders: Conditions like progressive systemic sclerosis or amyloidosis that affect the neuromuscular function of the intestines can lead to duodenal obstruction.
Symptoms of duodenal obstruction may include nausea, vomiting (often with bilious or fecal matter), abdominal pain, distention, and decreased bowel movements. Diagnosis typically involves imaging studies such as X-rays, CT scans, or upper gastrointestinal series to visualize the blockage. Treatment depends on the underlying cause but may involve surgery, endoscopic procedures, or medications to manage symptoms and address the obstruction.
Esophageal atresia is a congenital condition in which the esophagus, the tube that connects the throat to the stomach, does not develop properly. In most cases, the upper esophagus ends in a pouch instead of connecting to the lower esophagus and stomach. This condition prevents food and liquids from reaching the stomach, leading to difficulty swallowing and feeding problems in newborn infants. Esophageal atresia often occurs together with a congenital defect called tracheoesophageal fistula, in which there is an abnormal connection between the esophagus and the windpipe (trachea).
The medical definition of 'Esophageal Atresia' is:
A congenital anomaly characterized by the absence of a normal connection between the upper esophagus and the stomach, resulting in the separation of the proximal and distal esophageal segments. The proximal segment usually ends in a blind pouch, while the distal segment may communicate with the trachea through a tracheoesophageal fistula. Esophageal atresia is often associated with other congenital anomalies and can cause serious complications if not diagnosed and treated promptly after birth.
An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.
Intestinal atresia
Familial multiple intestinal atresia
Umbilical cord ulceration and intestinal atresia
Atresia
Right colic artery
TTC7A
Duodenal atresia
Strømme syndrome
Gastroschisis
Polysplenia
Sylvia Rexach
Orvar Swenson
Christiaan Barnard
Pneumoperitoneum
Amyoplasia
PLAGL1
Omphalocele
Spleen
Subacute combined degeneration of spinal cord
Annular pancreas
Fish oil (medical use)
Pulmonary agenesis
Consanguinity
Chromosome 2
Bowel obstruction
Small intestine
Serial transverse enteroplasty
List of MeSH codes (C16)
List of diseases (U)
List of diseases (I)
Intestinal atresia - Wikipedia
Small Intestinal Atresia and Stenosis: Practice Essentials, Pathophysiology, Etiology
Combined immunodeficiency with intestinal atresias | Immune Deficiency Foundation
Exome sequencing identifies mutations in the gene TTC7A in French-Canadian cases with hereditary multiple intestinal atresia |...
Intestinal atresia: Video, Anatomy & Definition | Osmosis
Intestinal Atresia | Profiles RNS
Inpatient Hospitalization Costs Associated with Birth Defects Among Persons Aged 65 Years - United States, 2019 | MMWR
Congenital Anomalies of the Digestive System | NCBDDD | CDC
Small Intestinal Adenocarcinoma Arising at the Anastomotic Site after Kasai Operation for Biliary Atresia: A Case Report and...
Management of the Infant With Gastroschisis
Dr. Marc Arkovitz, MD, Pediatric Surgery Specialist - Valhalla, NY | Sharecare
Gastrosquise fetal: predição de gastrosquise complexa com uso de parâmetros ultr...
Dr. Stephen Kim
Fenestrated duodenal membrane in a very low weight newborn
Hirschsprung Disease - Symptoms, Causes, Treatment | NORD
Fecal retention in a puppy in: Journal of the American Veterinary Medical Association Volume 261 Issue 9 (2023)
Pediatric Gastroenterology - Stanford Medicine Children's Health
Prenatal Drug Exposure - Pediatrics - Merck Manuals Professional Edition
Best Hospitals & Doctors in Abu Dhabi, UAE | NMC Healthcare
Annular pancreas: MedlinePlus Medical Encyclopedia
Aplasia Cutis Congenita Treatment & Management: Medical Care, Surgical Care, Consultations
AboutKidsHealth
Table 2 - Differences in SARS-CoV-2 Clinical Manifestations and Disease Severity in Children and Adolescents by Infecting...
Abdominal wall defect: MedlinePlus Genetics
General Surgery for Children - Private Hospital in London - Cromwell Hospital
Thalidomide Embryopathy: An Enigmatic Challenge
Annals of Pediatric Surgery
Neurodevelopmental outcome of patients with congenital gastrointestinal malformations: a systematic review and meta-analysis |...
Obstruction30
- Intestinal atresia is any congenital malformation of the structure of the intestine that causes bowel obstruction. (wikipedia.org)
- Large intestinal atresia or stenosis - also known as colonic atresia - is the complete or partial obstruction of the opening (lumen) within the colon. (cdc.gov)
- In an infant presenting with bilious vomiting, it is crucial to differentiate intrinsic duodenal obstruction from intestinal malrotation with a midgut volvulus. (medscape.com)
- Atresias should be distinguished from other causes of neonatal intestinal obstruction. (medscape.com)
- Individually, ileal atresia and Hirschsprung disease are frequent causes of intestinal obstruction. (medscape.com)
- Megacystis microcolon intestinal hypoperistalsis syndrome (MMIHS) is a rare congenital disorder and the most common cause of functional intestinal obstruction in newborns. (medscape.com)
- Colonic atresia causes intestinal obstruction , in which the colon is completely blocked. (nih.gov)
- Colonic stenosis can also cause intestinal obstruction and its complications. (nih.gov)
- Colonic atresia and stenosis may cause signs and symptoms due to intestinal obstruction. (nih.gov)
- Anyone with signs or symptoms of intestinal obstruction needs medical help right away. (nih.gov)
- Colonic stenosis can also cause intestinal obstruction, and signs and symptoms may be similar to those of colonic atresia. (nih.gov)
- Intestinal obstruction, from inflammatory adhesions or from Ladd bands, a component of malrotation, may complicate the infant's recovery. (medscape.com)
- Intestinal atresias are common causes for newborn bowel obstruction. (blueprintgenetics.com)
- Overview of Congenital Gastrointestinal Anomalies Most congenital gastrointestinal (GI) anomalies present as intestinal obstruction and frequently manifest as feeding difficulties, distention, emesis, and an inability to pass gas and stool. (msdmanuals.com)
- Ultrasonography suggested intestinal obstruction and abdominal X-ray showed a 'double-bubble' sign suggestive of intestinal atresia. (bmj.com)
- The newborn was diagnosed with early-onset neonatal sepsis secondary to intestinal obstruction and transferred to the neonatal intensive care unit. (bmj.com)
- It is the most frequent cause of INTESTINAL OBSTRUCTION in NEWBORNS . (bvsalud.org)
- Duodenal atresia is a congenital intestinal obstruction in the form of complete obliteration of the duodenal lumen (see the images below). (medscape.com)
- Duodenal stenosis (incomplete obstruction of the duodenal lumen) is discussed with duodenal atresia because the 2 disorders together represent a spectrum of similar intrauterine events. (medscape.com)
- One half of the neonates with duodenal atresia or stenosis are born prematurely, and hydramnios occurs in approximately 40% of neonates with duodenal obstruction. (medscape.com)
- In addition, duodenal atresia or duodenal stenosis is most commonly associated with trisomy 21 (see the following image), with about 22-30% of patients with duodenal obstruction having trisomy 21. (medscape.com)
- Because duodenal atresia or duodenal stenosis occurs in all cases of annular pancreas, the anomalous pancreas should be considered a secondary change rather than a primary cause of duodenal obstruction. (medscape.com)
- Intestinal obstruction (ileus) can occur in any part of the intestinal tract but most often develops in the small intestine as a result of its narrower lumen. (vin.com)
- Intestinal obstruction suspected by clinical and laboratory findings can be confirmed by radiography. (vin.com)
- Plain abdominal radiographs may show excessive bowel distention with gas usually proximal to the obstruction and fluid filled intestinal loops. (vin.com)
- The barium-impregnated polyethylene spheres (BIPS) are successfully used to detect physical (complete and partial) and functional intestinal obstruction. (vin.com)
- Ultrasonography is considered a useful imaging modality for the investigation of the intestinal obstruction. (vin.com)
- Advantages of ultrasonography compared to the conventional radiography in the diagnosis of intestinal obstruction include: the lack of ionizing radiation with the technique, no need for anaesthesia, reduction in the time required, observation of the intestinal motility, visualization of the intestinal wall layers and examination of adjacent structures such as lymph nodes, pancreas, liver and spleen that are not usually visible radiographically. (vin.com)
- The most consistent ultrasonographic findings in mechanical obstruction are the segmental fluid-filled dilated intestinal loops with increased or decreased peristaltic activity, pendulous movement of the ingesta, the presence of a foreign body or invaginated intestinal loops in the distended bowel and the presence of akinetic intestinal loops together with free abdominal fluid accumulation. (vin.com)
- However, intestinal foreign bodies, intussusceptions and intestinal tumours are the most common causes of intestinal obstruction in dogs and cats. (vin.com)
Volvulus4
- volvulus, intestinal strangulation via a hernia, or thromboembolism. (msdmanuals.com)
- In children the main causes include necrotizing enterocolitis, intestinal atresias, and intestinal volvulus. (nih.gov)
- Others presented with necrosis (n=3), perforation (n=3), volvulus (n=1) and jejunal atresia (n=1). (bezmialemscience.org)
- Gastroschisis can be either a complex abnormality involving other gastrointestinal anomalies, such as intestinal atresia, perforation, necrosis, volvulus, or a simple abnormality without other anomalies (1,2). (bezmialemscience.org)
Stenosis14
- Infants with stenosis instead of atresia are often not discovered until several days after birth. (wikipedia.org)
- Large intestinal atresia or stenosis should be suspected in the newborn infant who fails to pass meconium or stool, has abdominal distention and/or bilious vomiting. (cdc.gov)
- Atresia/stenosis location in large intestine. (cdc.gov)
- Applebaum H, Sydorak R. Duodenal atresia and stenosis--annular pancreas. (medscape.com)
- What are colonic atresia and stenosis? (nih.gov)
- At birth, colonic stenosis is rarer than colonic atresia. (nih.gov)
- Who is more likely to get colonic atresia and stenosis? (nih.gov)
- Experts don't know who is more likely to have colonic atresia and stenosis at birth. (nih.gov)
- Experts aren't sure what causes colonic atresia and stenosis to occur as birth defects. (nih.gov)
- How do doctors diagnose colonic atresia and stenosis? (nih.gov)
- To diagnose colonic atresia and stenosis, doctors ask about symptoms and medical history and perform a physical exam and imaging tests. (nih.gov)
- Doctors treat colonic atresia and stenosis with surgery to remove the blocked or narrowed part of the colon and attach the healthy ends of the colon to each other. (nih.gov)
- In some cases, doctors treat colonic atresia or stenosis with one operation. (nih.gov)
- Duodenal atresia The duodenum can be obstructed by atresia, stenosis, and pressure due to an extrinsic mass. (msdmanuals.com)
Esophageal atresia4
- Mutations in SOX2 have been associated anophthalmia/microphthalmia-esophageal atresia syndrome. (blueprintgenetics.com)
- Infants with major noncardiac congenital anomalies requiring neonatal surgery (esophageal atresia, intestinal atresia, anorectal malformation, and gastroschisis) have an increased risk of a neurodevelopmental delay [ 4 ]. (hindawi.com)
- I specialize in treating pediatric surgical patients with diseases including congenital abnormalities such as esophageal atresia, intestinal atresia, diaphragmatic hernias, cystic abnormalities of the lungs, Hirschsprung disease, anorectal malformations, gastroschisis and omphalocele. (rochester.edu)
- If a combination of esophageal atresia and duodenal atresia is present, ultrasonography is preferred. (medscape.com)
Jejunal atresia4
- This is most common in jejunal atresia. (wikipedia.org)
- Occasionally, there may be jaundice, which is most common in jejunal atresia. (wikipedia.org)
- Surgery was performed and type IIIb jejunal atresia was found. (bmj.com)
- Type IIIa/b jejunal atresia is associated with high incidence of poor outcome in lower socioeconomic countries. (bmj.com)
Gastroschisis1
- An infant with gastroschisis may have intestinal dysfunction. (medscape.com)
Multiple intestinal9
- citation needed] An inherited form - familial multiple intestinal atresia - has also been described. (wikipedia.org)
- Background Congenital multiple intestinal atresia (MIA) is a severe, fatal neonatal disorder, involving the occurrence of obstructions in the small and large intestines ultimately leading to organ failure. (bmj.com)
- Hereditary multiple intestinal atresia (MIA) (MIM (243150)) is a severe congenital disorder, first formally defined in 1973. (bmj.com)
- Intestinal transplantation in children with multiple intestinal atresias and immunodeficiency. (springer.com)
- Multiple intestinal atresia with combined immune deficiency. (springer.com)
- Compound heterozygous mutations in TTC7A cause familial multiple intestinal atresias and severe combined immunodeficiency. (springer.com)
- Multiple intestinal atresia with combined immune deficiency related to TTC7A defect is a multiorgan pathology: study of a French-Canadian-based cohort. (springer.com)
- Tetratricopeptide repeat domain 7A (TTC7A) mutation in a newborn with multiple intestinal atresia and combined immunodeficiency. (springer.com)
- Hereditary multiple intestinal atresia (HMIA) is a severe congenital disorder that is often fatal in the first months of life. (blueprintgenetics.com)
Abdominal5
- Abdominal tenderness or an abdominal mass are not generally seen as symptoms of intestinal atresia. (wikipedia.org)
- Meconium peritonitis, due to in-utero intestinal perforation, can be revealed by using plain abdominal imaging. (medscape.com)
- Neonates with jejunoileal atresia usually present late during day 1 or on day 2 with increasing abdominal distention, failure to pass stools, emesis, and feeding problems. (msdmanuals.com)
- The expectation is that the fellow will gain experience in the prenatal counseling of lung lesions, abdominal wall defects, congenital diaphragmatic hernia, and intestinal atresia. (cincinnatichildrens.org)
- If duodenal atresia is not diagnosed antenatally, the diagnosis can be made bt plain abdominal radiograph. (medscape.com)
Bowel12
- The distension is more generalised the further down the bowel the atresia is located and is thus most prominent with ileal atresia. (wikipedia.org)
- The most common cause of non-duodenal intestinal atresia is a vascular accident in utero that leads to decreased intestinal perfusion and ischemia of the respective segment of bowel. (wikipedia.org)
- citation needed] In the case that the superior mesenteric artery, or another major intestinal artery, is occluded, large segments of bowel can be entirely underdeveloped (Type III). (wikipedia.org)
- citation needed] If not diagnosed in utero, infants with intestinal atresia are typically diagnosed at day 1 or day 2 after presenting with eating problems, vomiting, and/or failure to have a bowel movement. (wikipedia.org)
- Duodenal atresia is a condition in which the first part of the small bowel (the duodenum ) has not developed properly. (medlineplus.gov)
- Doctors suspected the problem was an intestinal atresia - a portion of the intestine was blocked, affecting digestion and bowel movement. (wmfe.org)
- The causes of Short bowel syndrome in adults include Crohn disease, mesenteric ischemia, radiation enteritis, or surgical removal of half or more of the small intestine to treat intestinal diseases or injuries. (nih.gov)
- We specialize in helping you rehabilitate your or your child's intestine when the small bowel fails to ingest, digest, or absorb nutrients, water and electrolytes, an ailment called intestinal failure. (nebraskamed.com)
- Structural Intestinal failure - often called short-bowel syndrome (SBS). (nebraskamed.com)
- Intestinal microbiota in short bowel syndrome. (bcchr.ca)
- Note* If you are in India and considering Intestinal Transplant in India or abroad also known as , Intestinal Transplants in India and Intestine Transplantation in India or Intestinal treatment in India, Small Bowel Transplant in India, then you are at the right place. (medicaljump.com)
- Intestinal transplant also known as small bowel transplant in India is a procedure which helps to replace a shortened or diseased small intestine with healthy bowel from donor for intestine in India. (medicaljump.com)
Perforation2
- Peritoneal calcifications suggest the presence of meconium peritonitis, which is a sign of intrauterine intestinal perforation and can be seen in approximately 10% of cases. (msdmanuals.com)
- and perinatal intestinal perforation. (bvsalud.org)
Jejunoileal atresia2
- for instance a malformation that occurs along or spans the length of the jejunum and the ileum is termed jejunoileal atresia. (wikipedia.org)
- Jejunoileal atresia is incomplete formation of part of the small intestine. (msdmanuals.com)
Duodenal atresia is not1
- The cause of duodenal atresia is not known. (medlineplus.gov)
IIIb2
- In type IIIb, also known as the "apple peel" or "Christmas tree" deformity, the atresia affects the jejunum, and the intestine is often malrotated with most of the mesenteric arteries absent. (wikipedia.org)
- A midgut type IIIb intestinal atresia was found with an internal hernia through a mesenteric defect. (sages.org)
Anomalies1
- 18. New case of "apple-peel" intestinal atresia and ocular anomalies with mosaic variegated aneuploidy. (nih.gov)
Combined immunodeficiency2
- Whole-exome sequencing identifies tetratricopeptide repeat domain 7A (TTC7A) mutations for combined immunodeficiency with intestinal atresias. (springer.com)
- Mutations in tetratricopeptide repeat domain 7A (TTC7A) are associated with combined immunodeficiency with dendriform lung ossification but no intestinal atresia. (springer.com)
Infants6
- citation needed] A third of infants with intestinal atresia are born prematurely or with low birth weight. (wikipedia.org)
- One out of three infants with intestinal atresia are premature. (sages.org)
- Many infants with duodenal atresia also have Down syndrome . (medlineplus.gov)
- Incidence and antiviral treatment of cytomegalovirus infection in infants with biliary atresia. (amedeo.com)
- Biliary atresia is a rare liver disease that occurs in infants. (stanfordchildrens.org)
- Premature babies are at greater risk for biliary atresia than full-term infants. (stanfordchildrens.org)
Tract2
- Frequency of infiltrating regulatory T-cells in the portal tract of biliary atresia. (amedeo.com)
- This surgery connects the bile drainage from the liver directly to the intestinal tract. (stanfordchildrens.org)
Small intestinal2
- Compared to normotensive women, early pregnancy antihypertensive medication use was associated with increased risk of small intestinal atresia (adjusted OR 2.4, 95% CI 1.2-4.7) and anencephaly (adjusted OR 1.9, 95% CI 1.0-3.5). (nih.gov)
- Considering the vascular hypothesis for the pathogenesis of small intestinal atresia: a case control study of genetic factors. (cdc.gov)
Gastrointestinal1
- Is ideal for patients with gastrointestinal atresia. (blueprintgenetics.com)
Syndrome2
Ileal atresia1
- Ileal atresia can also result as a complication of meconium ileus. (wikipedia.org)
Oesophageal atresia1
- This is more common in duodenal and oesophageal atresia. (wikipedia.org)
Biliary atresia20
- Prednisolone administration monitored by postoperative stool color achieves high jaundice clearance after laparoscopic portoenterostomy for biliary atresia. (amedeo.com)
- Outcomes of adult native liver survivors with biliary atresia: the current situation in Japan. (amedeo.com)
- Development of liver inflammatory injury in biliary atresia: from basic to clinical research. (amedeo.com)
- The correlation between rs2501577 gene polymorphism and biliary atresia: a systematic review and meta-analysis. (amedeo.com)
- Laparoscopic versus open portoenterostomy for treatment of biliary atresia: a meta-analysis. (amedeo.com)
- Laparoscopic versus open Kasai procedure for biliary atresia: long-term results of a randomized clinical trial. (amedeo.com)
- When a child has biliary atresia, the bile ducts in the liver are blocked. (stanfordchildrens.org)
- Biliary atresia must be treated with surgery. (stanfordchildrens.org)
- What causes biliary atresia in a child? (stanfordchildrens.org)
- Experts don't know what causes biliary atresia. (stanfordchildrens.org)
- Which children are at risk for biliary atresia? (stanfordchildrens.org)
- What are the symptoms of biliary atresia in a child? (stanfordchildrens.org)
- Babies with biliary atresia usually seem healthy at birth. (stanfordchildrens.org)
- Symptoms of biliary atresia may look like other liver conditions or health problems. (stanfordchildrens.org)
- How is biliary atresia diagnosed in a child? (stanfordchildrens.org)
- If the isotope passes through the liver into the intestine, the bile ducts are open and the child does not have biliary atresia. (stanfordchildrens.org)
- A biopsy can tell if biliary atresia is likely. (stanfordchildrens.org)
- If biliary atresia is diagnosed, the surgeon may treat it with surgery at the same time. (stanfordchildrens.org)
- How is biliary atresia treated in a child? (stanfordchildrens.org)
- Without surgery, biliary atresia can be fatal. (stanfordchildrens.org)
Symptoms1
- Your child may have one or more intestinal and immune symptoms of TTC7A deficiency, which can vary in severity. (childrenshospital.org)
Dilated intestinal segment1
- either during a routine sonogram which shows a dilated intestinal segment due to the blockage, or by the development of polyhydramnios (the buildup of too much amniotic fluid in the uterus). (wikipedia.org)
Colonic3
Transplant7
- Intestinal Transplant (incl. (sharecare.com)
- Our expertise has helped many patients avoid intestinal transplant surgery. (nebraskamed.com)
- Transplantation, including isolated intestinal transplant and liver/intestine/pancreas (multivisceral) transplantation, when medical or surgical treatment interventions fail. (nebraskamed.com)
- Our intestinal failure team provides patients and their families with extensive support and education throughout the transplant journey, and even after they return home. (nebraskamed.com)
- We at best medical surgery help our clients from India with International Medical tourism for Intestinal Transplant in India and International Locations. (medicaljump.com)
- In India, successful Intestinal transplant surgery , along with medication and routine check-up can help the patient to live healthy life in India. (medicaljump.com)
- Why is Intestinal transplant in India is needed? (medicaljump.com)
TTC7A3
- TTC7A mutations disrupt intestinal epithelial apicobasal polarity. (springer.com)
- The Division of Gastroenterology, Hepatology and Nutrition at Boston Children's Hospital specializes in diagnosing and treating children with complex intestinal disorders including TTC7A deficiency. (childrenshospital.org)
- Using this approach, the laboratory has identified several new gene defects, including DOCK2 deficiency, TTC7A deficiency (responsible for combined immune deficiency and intestinal atresias), HOIP deficiency (a cause of immune deficiency and autoinflammatory disease), EXTL3 deficiency (associating severe T-cell immunodeficiency, skeletal dysplasia, and neurodevelopmental delay), PAX1 deficiency and SASH3 deficiency. (nih.gov)
Liver3
- Comprehensive medical care for adult and pediatric patients with complex liver and intestinal diseases. (nebraskamed.com)
- The calorie-dense lipids in total parenteral nutrition (TPN) help keep the intestinal failure patients alive, but the type used in the United States (made from soybean oil) contains a high amount of Omega-6 fatty acids, which can lead to cirrhosis of the liver. (nebraskamed.com)
- I am also interested in determining how changes to the gut bacteria impact the body's immune system and overall level of inflammation potentially predisposing children with intestinal failure to infection, liver disease, and blood clots. (bcchr.ca)
Diagnosis1
- Even when the diagnosis of duodenal atresia is established in the stable patient, cardiac anatomy and function should be evaluated before surgical correction. (medscape.com)
Bilious2
- The most prominent symptom of intestinal atresia is bilious vomiting soon after birth. (wikipedia.org)
- Duodenal atresia can cause bilious or nonbilious vomiting within the first 24 to 38 hours after birth, typically following the first oral feeding. (medscape.com)
Transplantation1
- A multidisciplinary intestinal rehabilitation program for patients on total parenteral nutrition (TPN), focusing on decreasing their need for TPN with the goal of preventing or delaying the need for transplantation. (nebraskamed.com)
Occur1
- Jejunoileal atresias occur as a result of an ischemic insult during pregnancy. (msdmanuals.com)
Distal2
- The affected intestinal segment and a distal serosal tear were resected and two end-to-end anastomoses formed. (bmj.com)
- Plain radiographs that demonstrate a double-bubble appearance with no distal gas are characteristic of duodenal atresia (see the images below). (medscape.com)