BenzaldehydesVanillic Acid: A flavoring agent. It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin. (J Biotechnol 1996;50(2-3):107-13).Vanilla: A plant genus of the family ORCHIDACEAE that is the source of the familiar flavoring used in foods and medicines (FLAVORING AGENTS).Flavoring Agents: Substances added to foods and medicine to improve the quality of taste.Eugenol: A cinnamate derivative of the shikamate pathway found in CLOVE OIL and other PLANTS.Coumaric Acids: Hydroxycinnamic acid and its derivatives. Act as activators of the indoleacetic acid oxidizing system, thereby producing a decrease in the endogenous level of bound indoleacetic acid in plants.Guaiacol: An agent thought to have disinfectant properties and used as an expectorant. (From Martindale, The Extra Pharmacopoeia, 30th ed, p747)Antimutagenic Agents: Agents that reduce the frequency or rate of spontaneous or induced mutations independently of the mechanism involved.Ribosome Subunits, Large: The largest ribonucleoprotein component of RIBOSOMES. It contains the domains which catalyze formation of the peptide bond and translocation of the ribosome along the MESSENGER RNA during GENETIC TRANSLATION.Food Quality: Ratings of the characteristics of food including flavor, appearance, nutritional content, and the amount of microbial and chemical contamination.Oxidoreductases, O-Demethylating: Drug metabolizing enzymes which oxidize methyl ethers. Usually found in liver microsomes.Aberrant Crypt Foci: Clusters of colonic crypts that appear different from the surrounding mucosa when visualized after staining. They are of interest as putative precursors to colorectal adenomas and potential biomarkers for colorectal carcinoma.Benzyl Alcohols: Alcohols derived from the aryl radical (C6H5CH2-) and defined by C6H5CHOH. The concept includes derivatives with any substituents on the benzene ring.Hydroxybenzoates: Benzoate derivatives substituted by one or more hydroxy groups in any position on the benzene ring.Aldehyde Oxidoreductases: Oxidoreductases that are specific for ALDEHYDES.Metabolic Engineering: Methods and techniques used to genetically modify cells' biosynthetic product output and develop conditions for growing the cells as BIOREACTORS.Enoyl-CoA Hydratase: An enzyme that catalyzes reversibly the hydration of unsaturated fatty acyl-CoA to yield beta-hydroxyacyl-CoA. It plays a role in the oxidation of fatty acids and in mitochondrial fatty acid synthesis, has broad specificity, and is most active with crotonyl-CoA. EC 4.2.1.17.Sulfonic Acids: Inorganic or organic oxy acids of sulfur which contain the RSO2(OH) radical.Cesium Radioisotopes: Unstable isotopes of cesium that decay or disintegrate emitting radiation. Cs atoms with atomic weights of 123, 125-132, and 134-145 are radioactive cesium isotopes.Industrial Microbiology: The study, utilization, and manipulation of those microorganisms capable of economically producing desirable substances or changes in substances, and the control of undesirable microorganisms.PicratesProtocatechuate-3,4-Dioxygenase: An enzyme that catalyzes the oxidation of protocatechuate to 3-carboxy-cis-cis-muconate in the presence of molecular oxygen. It contains ferric ion. EC 1.13.11.3.Formazans: Colored azo compounds formed by the reduction of tetrazolium salts. Employing this reaction, oxidoreductase activity can be determined quantitatively in tissue sections by allowing the enzymes to act on their specific substrates in the presence of tetrazolium salts.Drug Packaging: Containers, packaging, and packaging materials for drugs and BIOLOGICAL PRODUCTS. These include those in ampule, capsule, tablet, solution or other forms. Packaging includes immediate-containers, secondary-containers, and cartons. In the United States, such packaging is controlled under the Federal Food, Drug, and Cosmetic Act which also stipulates requirements for tamper-resistance and child-resistance. Similar laws govern use elsewhere. (From Code of Federal Regulations, 21 CFR 1 Section 210, 1993) DRUG LABELING is also available.Pyruvate Decarboxylase: Catalyzes the decarboxylation of an alpha keto acid to an aldehyde and carbon dioxide. Thiamine pyrophosphate is an essential cofactor. In lower organisms, which ferment glucose to ethanol and carbon dioxide, the enzyme irreversibly decarboxylates pyruvate to acetaldehyde. EC 4.1.1.1.Lignin: The most abundant natural aromatic organic polymer found in all vascular plants. Lignin together with cellulose and hemicellulose are the major cell wall components of the fibers of all wood and grass species. Lignin is composed of coniferyl, p-coumaryl, and sinapyl alcohols in varying ratios in different plant species. (From Merck Index, 11th ed)Odors: The volatile portions of substances perceptible by the sense of smell. (Grant & Hackh's Chemical Dictionary, 5th ed)Sphingomonas: A genus of gram-negative, aerobic, rod-shaped bacteria characterized by an outer membrane that contains glycosphingolipids but lacks lipopolysaccharide. They have the ability to degrade a broad range of substituted aromatic compounds.Dosage Forms: Completed forms of the pharmaceutical preparation in which prescribed doses of medication are included. They are designed to resist action by gastric fluids, prevent vomiting and nausea, reduce or alleviate the undesirable taste and smells associated with oral administration, achieve a high concentration of drug at target site, or produce a delayed or long-acting drug effect.Benzothiazoles: Compounds with a benzene ring fused to a thiazole ring.Olfactory Perception: The process by which the nature and meaning of olfactory stimuli, such as odors, are recognized and interpreted by the brain.Biosynthetic Pathways: Sets of enzymatic reactions occurring in organisms and that form biochemicals by making new covalent bonds.Volatilization: A phase transition from liquid state to gas state, which is affected by Raoult's law. It can be accomplished by fractional distillation.Glycosyltransferases: Enzymes that catalyze the transfer of glycosyl groups to an acceptor. Most often another carbohydrate molecule acts as an acceptor, but inorganic phosphate can also act as an acceptor, such as in the case of PHOSPHORYLASES. Some of the enzymes in this group also catalyze hydrolysis, which can be regarded as transfer of a glycosyl group from the donor to water. Subclasses include the HEXOSYLTRANSFERASES; PENTOSYLTRANSFERASES; SIALYLTRANSFERASES; and those transferring other glycosyl groups. EC 2.4.Hemoglobin, Sickle: An abnormal hemoglobin resulting from the substitution of valine for glutamic acid at position 6 of the beta chain of the globin moiety. The heterozygous state results in sickle cell trait, the homozygous in sickle cell anemia.Biotechnology: Body of knowledge related to the use of organisms, cells or cell-derived constituents for the purpose of developing products which are technically, scientifically and clinically useful. Alteration of biologic function at the molecular level (i.e., GENETIC ENGINEERING) is a central focus; laboratory methods used include TRANSFECTION and CLONING technologies, sequence and structure analysis algorithms, computer databases, and gene and protein structure function analysis and prediction.Pseudomonas fluorescens: A species of nonpathogenic fluorescent bacteria found in feces, sewage, soil, and water, and which liquefy gelatin.Free Radical Scavengers: Substances that influence the course of a chemical reaction by ready combination with free radicals. Among other effects, this combining activity protects pancreatic islets against damage by cytokines and prevents myocardial and pulmonary perfusion injuries.Chemical Fractionation: Separation of a mixture in successive stages, each stage removing from the mixture some proportion of one of the substances, for example by differential solubility in water-solvent mixtures. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Biotransformation: The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the production of an active metabolite of an inactive parent compound. The alterations may be divided into METABOLIC DETOXICATION, PHASE I and METABOLIC DETOXICATION, PHASE II.Plant Extracts: Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.Phenols: Benzene derivatives that include one or more hydroxyl groups attached to the ring structure.Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.Coenzyme A Ligases: Enzymes that catalyze the formation of acyl-CoA derivatives. EC 6.2.1.Coenzymes: Small molecules that are required for the catalytic function of ENZYMES. Many VITAMINS are coenzymes.Molecular Structure: The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.Chromatography, High Pressure Liquid: Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.Hydro-Lyases: Enzymes that catalyze the breakage of a carbon-oxygen bond leading to unsaturated products via the removal of water. EC 4.2.1.Biphenyl CompoundsCatechols: A group of 1,2-benzenediols that contain the general formula R-C6H5O2.Smell: The ability to detect scents or odors, such as the function of OLFACTORY RECEPTOR NEURONS.Actinomycetales: An order of gram-positive, primarily aerobic BACTERIA that tend to form branching filaments.Crystallography: The branch of science that deals with the geometric description of crystals and their internal arrangement. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Benzhydryl Compounds: Compounds which contain the methyl radical substituted with two benzene rings. Permitted are any substituents, but ring fusion to any of the benzene rings is not allowed.Escherichia coli: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.Pseudomonas: A genus of gram-negative, aerobic, rod-shaped bacteria widely distributed in nature. Some species are pathogenic for humans, animals, and plants.Chromans: Benzopyrans saturated in the 2 and 3 positions.Substrate Specificity: A characteristic feature of enzyme activity in relation to the kind of substrate on which the enzyme or catalytic molecule reacts.Oxidation-Reduction: A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).Biocatalysis: The facilitation of biochemical reactions with the aid of naturally occurring catalysts such as ENZYMES.Rheology: The study of the deformation and flow of matter, usually liquids or fluids, and of the plastic flow of solids. The concept covers consistency, dilatancy, liquefaction, resistance to flow, shearing, thixotrophy, and VISCOSITY.Anticonvulsants: Drugs used to prevent SEIZURES or reduce their severity.NAD: A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)Carbon: A nonmetallic element with atomic symbol C, atomic number 6, and atomic weight [12.0096; 12.0116]. It may occur as several different allotropes including DIAMOND; CHARCOAL; and GRAPHITE; and as SOOT from incompletely burned fuel.
This allows researchers to study the interaction between the fungus and its host with relative ease. The availability of the ... Flavor compounds include sotolon and vanillin, as well as the sugar glucose. The fungus has had difficulty entering into the ...
Well known tyrosinase inhibitors include kojic acid, tropolone, coumarins, vanillic acid, vanillin, and vanillic alcohol. ... interactions between KIT and MITF". Development. 127 (24): 5379-89. PMID 11076759. Hoek KS, Schlegel NC, Eichhoff OM, Widmer DS ... "Interaction of sesamol (3,4-methylenedioxyphenol) with tyrosinase and its effect on melanin synthesis". Biochimie. 93 (3): 562- ...
The agave plant contains many terpenes such as vanillin and syringaldehydes which presents a strong and fruity or herbal aroma ... depends on the interaction and quantity of each volatile compound. The volatile compounds responsible for the flavor and aroma ...
Though females nest in aggregations, this is due more to lack of suitable locations than any social interactions. They work ... surinamensis males have a marked preference for the compound vanillin, compared to 1.8 cineole and eugenol. Nesting female bees ... "Nesting aggregations of the euglossine bee Euplusia surinamensis (Hymenoptera: Apidae): individual interactions and the ...
Any binding interaction of an odorant molecule with an olfactory receptor will therefore be likely to show some isotope effect ... to test Turin's theory that the mixture should smell of vanillin. Vosshall and Keller's data did not support Turin's prediction ... Turin points out that traditional lock-and-key receptor interactions deal with agonists, which increase the receptor's time ...
Artificial vanilla flavors vanillin and ethylvanillin are a notable exception, as well as the artificial strawberry flavor ( ... The role of cognitive influences in color-flavor interactions". Consciousness and Cognition. 19 (1): 380-90. doi:10.1016/j. ...
Hay, M E; Fenical, W (1988). "Marine Plant-Herbivore Interactions: The Ecology of Chemical Defense". Annual Review of Ecology ... The localization of phlorotannins can be investigated by light microscopy after vanillin-HCl staining giving an orange color. ... "Phlorotannin-protein interactions". Journal of Chemical Ecology. 22 (10): 1877. doi:10.1007/BF02028510. Riitta Koivikko, 2008, ...
Altogether, the interactions of cross-modal seems to be a rather frequent occurrence. The results of these studies underline ... It was discovered that when pure odorants such as hydrogen sulfide or vanillin were used as stimulants localization was random ... Another similar modulation interaction is between audition and touch. The contralesional tactile detection is hampered by ... has been linked to a number of cognitive functions that suggest a role in modulating competitive interactions between stimulus ...
Likewise vanillin would be a hydrolytic degradation product of phyllalbine just as methyl benzoate is for cocaine. The alkaloid ... and exhibiting preferential interaction with outward facing DAT conformation, they appear to have the lack of behavioral ... A more direct route to vanillic acid though is just oxidation of the vanillin to a functionalized benzoic acid. The MAT binding ... "Interaction of cocaine-, benztropine-, and GBR12909-like compounds with wild-type and mutant human dopamine transporters: ...
Because of the reduced intermolecular van der Waals interactions, fluorocarbon-based compounds are sometimes used as lubricants ... and vanillin. 2,2,2-trifluoroethanol is an oxidation-resistant polar solvent. The development of organofluorine chemistry has ... "Arene-perfluoroarene interactions in crystal engineering: structural preferences in polyfluorinated tolans". J. Mater. Chem. 14 ... resulting from donor-acceptor interactions between the pi-systems. Polymeric organofluorine compounds are numerous and ...
doi:10.1007/s12225-015-9604-7. "Peru Balsam: Uses, Side Effects, Interactions and Warnings". WebMD. Retrieved March 13, 2014. ... and vanillin. It also contains cinnamic acid alcohol and aldehyde, farnesol, and nerolidol. A minority of it, approximately 30- ...
Natural phenols can be involved in allelopathic interactions, for example in soil or in water. Juglone is an example of such a ... vanillin have been isolated from in vitro culture of the freshwater green alga Spongiochloris spongiosa. Phlorotannins, for ... Brencic, Anja; Winans, Stephen C. (March 2005). "Detection of and Response to Signals Involved in Host-Microbe Interactions by ... Amorati, R; Valgimigli, L. (2012). "Modulation of the antioxidant activity of phenols by non-covalent interactions". Org Biomol ...
Vanillin is a phenolic aldehyde most commonly associated with the vanilla notes in wines that have been aged in oak. Trace ... Dufour, C; Bayonove, C. L. (1999). "Interactions between wine polyphenols and aroma substances. An insight at the molecular ... The process of oak aging can also introduce phenolic compounds into wine, most notably vanillin which adds vanilla aroma to ... Oak barrel will add compounds such as vanillin and hydrolysable tannins (ellagitannins). The hydrolyzable tannins present in ...
Changed: 'ImageFile' ('Vanillin.png' -, 'Vanillin2.svg', SET 'Vanillin.png'). *20:50:13 (2, 4, 5) (EDIT) User:JWBE (contribs, ... 20:50:14 (4, 4, 5) (EDIT) User:JWBE (contribs, talk) edited Vanillin (diff, hist). Changed: 'MeltingPt' ('80-81°C (353-354 K ... 20:50:14 (4, 4, 5) (EDIT) User:JWBE (contribs, talk) edited Vanillin (diff, hist). Changed: 'BoilingPt' ('285°C (558 K)' -, ' ... 20:50:12 (2, 4, 5) (EDIT) User:JWBE (contribs, talk) edited Vanillin (diff, hist). ...
Oxidation of lignosulfonates was used to produce vanillin (artificial vanilla), and this process is still used by one supplier ... "Vanillin: Synthetic Flavoring from Spent Sulfite Liquor" (PDF). Journal of Chemical Education. 74 (9): 1055. Bibcode:1997JChEd ...
... fruits can contain gallic acid, gentisic acid, syringic acid, vanillin, ferulic acid, sinapic acid, isoferulic acid, ... pages 1372-1378 Major Polyphenolics in Pineapple Peels and their Antioxidant Interactions. Ti Li, Peiyi Shen, Wei Liu, Chengmei ...
Diacylglycerol has been shown to exert some of its excitatory actions on vesicle release through interactions with the ...
Interactions[edit]. TRPC5 has been shown to interact with STMN3,[12] TRPC1,[13][14] and TRPC4.[14] ... "Formation of novel TRPC channels by complex subunit interactions in embryonic brain". J. Biol. Chem. 278 (40): 39014-9. doi: ...
Archeological excavations in the Indus Valley (Indian Subcontinent) have revealed that mustard was cultivated there. That civilization existed until about 1800 BC.[5] The Romans were probably the first to experiment with the preparation of mustard as a condiment. They mixed unfermented grape juice (the must) with ground mustard seeds (called sinapis) to make "burning must", mustum ardens - hence "must ard".[6] A recipe for mustard appears in De re coquinaria, the anonymously compiled Roman cookbook from the late fourth or early fifth century; the recipe calls for a mixture of ground mustard, pepper, caraway, lovage, grilled coriander seeds, dill, celery, thyme, oregano, onion, honey, vinegar, fish sauce, and oil, and was intended as a glaze for spit-roasted boar.[7] The Romans likely exported mustard seed to Gaul, and by the 10th century, monks of Saint-Germain-des-Prés in Paris absorbed the mustard-making knowledge of Romans and began their own production.[8] The first appearance of mustard ...
... is a chemical extracted from the plant genus Tetradium, which has been shown to reduce fat uptake in mouse studies. It is suspected that its mechanism of action is similar to that of capsaicin.[1] As such, it has been included in some dietary supplements. Neither its fat-burning effects in humans nor any potential side effects have been empirically established. Evodiamine acts primarily as a thermogenic and stimulant.[2] Evodiamine may also act in a manner comparable to tianeptine by increasing the number of serotonin transporters available in the brain, enhancing the reuptake of serotonin.[3] ...
Chu X, Tong Q, Cheung JY, Wozney J, Conrad K, Mazack V, Zhang W, Stahl R, Barber DL, Miller BA (March 2004). "Interaction of ...
... is a potent endothelium-dependent vasodilator, leading to a drop in blood pressure. It also causes contraction of non-vascular smooth muscle in the bronchus and gut, increases vascular permeability and is also involved in the mechanism of pain.[4] Bradykinin also causes natriuresis, contributing to the drop in blood pressure. Bradykinin raises internal calcium levels in neocortical astrocytes causing them to release glutamate, though this finding has only been confirmed in-vitro.[5] Bradykinin is also thought to be the cause of the dry cough in some patients on widely prescribed angiotensin-converting enzyme (ACE) inhibitor drugs. It is thought that bradykinin is converted to inactive metabolites by ACE, therefore inhibition of this enzyme leads to increased levels of bradykinin, which causes a dry cough via bronchoconstriction. In severe cases, the elevation of bradykinin may result in angioedema, a medical emergency.[6] People of African descent have up to 5x increased risk of ACE ...
... (2-APB) is a chemical that acts to inhibit both IP3 receptors[1] and TRP channels (although it activates TRPV1, TRPV2, & TRPV3 at higher concentrations).[2][3] In research it is used to manipulate intracellular release of calcium ions (Ca2+) and modify TRP channel activity, although the lack of specific effects make it less than ideal under some circumstances. Additionally, there is evidence that 2-APB acts directly to inhibit gap junctions made of connexin.[4] Increasing evidence showed that 2-APB is a powerful modifier of store-operated calcium channels (SOC) function, low concentration of 2-APB can enhance SOC while high concentration induces a transient increase followed by complete inhibition.[5][6][7] ...
This stimulation appears due to a direct interaction of these agents on TRPV1 although reports disagree on the potencies of the ... The OXLAM-TRPV1 interaction is credited with mediating pain sensation in rodents (see below). ...
... is used as an insecticide and insect repellent.[5][6]. In contrast, eucalyptol is one of many compounds that are attractive to males of various species of orchid bees, which gather the chemical to synthesize pheromones; it is commonly used as bait to attract and collect these bees for study.[7] One such study with Euglossa imperialis, a non-social orchid bee species, has shown that the presence of cineole (also eucalyptol), elevates territorial behavior and specifically attracts the male bees. It was even observed that these males would periodically leave their territories to forage for chemicals such as cineole, thought to be important for attracting and mating with females, to synthesize pheromones.[8]. ...
... is an aromatic evergreen shrub with leaves similar to hemlock needles. It is native to the Mediterranean and Asia, but is reasonably hardy in cool climates. It can withstand droughts, surviving a severe lack of water for lengthy periods.[8] Forms range from upright to trailing; the upright forms can reach 1.5 m (5 ft) tall, rarely 2 m (6 ft 7 in). The leaves are evergreen, 2-4 cm (0.8-1.6 in) long and 2-5 mm broad, green above, and white below, with dense, short, woolly hair. The plant flowers in spring and summer in temperate climates, but the plants can be in constant bloom in warm climates; flowers are white, pink, purple or deep blue.[2] Rosemary also has a tendency to flower outside its normal flowering season; it has been known to flower as late as early December, and as early as mid-February (in the northern hemisphere).[9] In some parts of the world, it is considered an invasive species.[2] ...
Bindings of vanillin with casein and whey protein were enthalpy driven, while the interaction of vanillin with soy protein was ... Interaction of Vanillin with Soy and Dairy Proteins in Aqueous Model Systems: A Thermodynamic Study. Authors. *. Z. Li,. * ... ABSTRACT: Interactions of vanillin with soy, casein, and whey proteins were studied in aqueous model systems using a ... Hema Jegasothy, Louise Bennett, Regine Stockmann, Interactions of α-ionone, β-ionone and vanillin with the primary genetic ...
"Assessment of interaction of vanillin with barley, pea and whey proteins: Binding properties and sensory characteristics, LWT ... The interaction between vanillin and barley proteins, estimated using Klotz plots of unbound vanillin, was found to be non- ... The interaction between vanillin and barley proteins, estimated using Klotz plots of unbound vanillin, was found to be non- ... Assessment of interaction of vanillin with barley, pea and whey proteins: Binding properties and sensory characteristics. Houde ...
... drug interactions, warnings, patient labeling, reviews, and related medications. ... and vanillin. *Individual tablets also contain: ... DRUG INTERACTIONS. Effects Of Co-Administered Drugs On ... Drugs For Which Either No Interaction Or A Likely Clinically Unimportant Interaction Has Been Observed. Antacids ... Drugs For Which Either No Interaction Or A Likely Clinically Unimportant Interaction Has Been Observed. Acetaminophen ...
Temporal patterns of nasal, oral and retronasal perception of citral and vanillin and interactions of these odorants with ... Interactions between oral burn, meat flavor and texture in chili spiced pork patties evaluated by time-intensity. Food Quality ... Proceedings, COST96 Meeting: Interaction of Food Matrix with Small Ligands Influencing Flavour and Texture, Dijon, France, ... Temporal perception of sweetness and fruitiness and their interaction in a model system. MS Thesis, University of California, ...
During this time, vanillin is produced by the enzymatic conversion of glucovanillin within the bean. Vanillin may accumulate as ... Interactions. None well documented.. Adverse Reactions. Although allergenic properties have been associated with vanilla, they ... In a study in sickle cell disease, vanillin 1 g daily was given in divided doses for 40 days.García 2005 Because vanillin is ... The quality of the vanilla bean is not dependent on the vanillin content even though vanillin is associated with the ...
1: protein-protein interaction networks, with increased coverage and integration. Nucleic Acids Res 41(D1):D808-D815CrossRef ... Strain ATCC 39116 towards Enhanced Production of Natural Vanillin. Appl Environ Microbiol 82(11):3410-3419CrossRefPubMed ... Wang Y, Cui T, Zhang C, Yang M, Huang Y, Li W, Zhang L, Gao C, He Y, Li Y (2010) Global protein−protein interaction network in ... The transcriptional regulatory network of Corynebacterium jeikeium K411 and its interaction with metabolic routes contributing ...
Previous Document: Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-.... ... 0/Benzaldehydes; 0/Flavoring Agents; 121-33-5/vanillin; 22839-47-0/Aspartame; 57-50-1/Sucrose ...
Drug/Laboratory Test Interactions. Methyldopa may interfere with measurement of: urinary uric acid by the phosphotungstate ... by those methods which convert VMA to vanillin. Methyldopa is not recommended for the treatment of patients with ... Drug Interactions. When methyldopa is used with other antihypertensive drugs, potentiation of antihypertensive effect may occur ...
As with the resveratrol-bound structure, residue F59 provided aromatic stacking interactions. The aldehyde group of vanillin ... S6, trace A shows the EPR spectrum of the NOV1 mixed with NO and vanillin, a product analog. The NOV1-NO-vanillin spectrum was ... An additional 5 mM vanillin was added to the crystallization buffer to obtain the vanillin-bound structure. Cube-like crystals ... The NOV1 plus vanillin complex was prepared with either 170 or 190 µM enzyme and a final vanillin concentration of 10 mM. ...
4.5 Interaction with other medicinal products and other forms of interaction. When methyldopa is used with other ... Methyldopa does not interfere with measurements of VMA (vanillylmandelic acid) by those methods which convert VMA to vanillin. ... Interaction with haloperidol has been reported. When methyldopa and lithium are given concomitantly the patient should be ...
... we noticed that the score of the hydrophobic interaction between Val109 with other ligands, such as ethyl vanillin (EV) ( ... Thus, mOR-EG did not respond to vanillin isomers such as isovanillin (R1 = -CHO, R3 = -OH, and R4 = -OCH3) and o-vanillin (R1 ... indicating that these residues are not involved in electrostatic interactions but rather in van der Waals interactions (Fig. 3A ... 1A, compound 4) and vanillin (compound 5), with variations at the R1, R3, and R4 positions on the benzene ring (Kajiya et al., ...
... stimulated mouse podocyte cell line MPC5 did not affect TLR2 expression but interrupted the interaction between TLR2 and its ... Therefore, the potential renal protective effects of ortho‑vanillin (OV), an inhibitor of TLR2, were investigated in the ... vanillin alleviates lipopolysaccharide‑induced acute kidney injury in mice. Experimental and Therapeutic Medicine 18, no. 6 ( ... vanillin alleviates lipopolysaccharide‑induced acute kidney injury in mice. Experimental and Therapeutic Medicine, 18, 4829- ...
We provide mechanistic insights into this dichotomy and further dissect the interactions of the food additive vanillin. Finally ... Effect of Sec61 interaction with Mpd1 on endoplasmic reticulum-associated degradation. Pereira, Fabio; Rettel, Mandy; Stein, ... Monitoring drug-target interactions with methods such as the cellular thermal-shift assay (CETSA) is well established for ... Thermal proteome profiling for interrogating protein interactions. Mateus, André; Kurzawa, Nils; Becher, Isabelle; Sridharan, ...
"Dependence of temperature on the corrosion protection properties of vanillin and its derivative, HMATD, towards copper in ... The interaction and corrosion protection properties of vanillin and one of its derivatives, HMATD, on copper in nitric acid ( ... The interaction and corrosion protection properties of vanillin and one of its derivatives, HMATD, on copper in nitric acid ( ... vanillin was found to be more effective. From spectroscopic and pH measurements, it is evident that vanillin has undergone a ...
In this work we investigate theoretically the interaction between the set of different ligands (such as vanillin, thymoquinone ... conformations in which the donor/acceptor interactions are mediated by the interaction of Ru-unbound ligands with groups of the ... Theoretical investigation of interaction between the set of ligands and α7 nicotinic acetylcholine receptor ... We conducted a series of ab initio calculations of the donor/acceptor interaction in protein fragments and compared the ...
The use of Galleria mellonella larvae as preclinical in vivo model system to study host-pathogen interactions, virulence, ... with the interactions largely being species-specific, indicating a potential for synergistic drug interactions to provide ... This study showed colistin-clarithromycin and spectinomycin-vanillin to display synergistic activities against E. coli and K. ... Some antagonistic interactions were shown to affect both growth inhibition and drug efflux, with the second drug causing a ...
2. K.Kan, M. Akashi, H. Ajiro*, "Polylactides Bearing Vanillin at Chain End Provided Dual Dynamic Interactions: Stereocomplex ... Nanoparticles, nanofibers, and nanofilms are design and prepared using polymer-polymer interactions, such as van der Waals and ...
Intermolecular interactions of cis-3-hexen-1-ol or 1-hexanol with n-hexane: Thermodynamic study, FT-IR analysis and quantum ... Nucleation behavior of ethyl vanillin: Balance between chemical potential difference and saturation temperature. Publication ... Molecular interactions of L-Histidine in aqueous ionic liquid [C4mim][BF4] solution at different temperatures: Volumetric, ... In silico prediction of binding capacity and interaction forces of organic compounds with α- and β-cyclodextrins. Publication ...
Three-way interaction among plants, bacteria, and coleopteran insects Beata Wielkopolan, Aleksandra Obrępalska-Stęplowska. ( ... plant-microbe interactions - structural biology - and systems biology Review articles summarize recent advances in topical ... Ecological turmoil in evolutionary dynamics of plant-insect interactions: defense to offence Manasi Mishra, Purushottam R. ... Functional roles of the pepper leucine-rich repeat protein and its interactions with pathogenesis-related and hypersensitive- ...
7. Aroma perceptual interactions of benzaldehyde, furfural, and vanillin and their effects on the descriptor intensities of ... The molecular interactions between the phenolic acids and milk proteins impacts their functional performance and product ... The perceptual interactions of 3 important aldehyde compounds were investigated using S-curves. Three volatiles, benzaldehyde, ... In this study, the interactions between a milk protein (β-casein) and a number of phenolic acids was investigated: 3,4- ...
... or plant cells can produce vanillin or vanillin beta-D-glucoside. ... polypeptide alone or in combination with one or more vanillin ... In one embodiment, the forcefield is AMBER99 and the interaction energy between an amino acid and the protein-substrate ... Glucosylation of vanillin is particularly useful. Vanillin-β-D-glucoside is the storage form of vanillin found in the vanilla ... levels of vanillin-glucoside and iso-vanillin-glucoside may be determined instead of the levels of vanillin and iso-vanillin, ...
Vanillin, Sodium Chloride, Citrus Paradisi (Grapefruit) Seed Extract, Vanilla Planifolia Fruit Extract, Phenoxyethanol, Benzyl ... Drug Interactions. Warnings. Common Uses. Ingredients. Water (Aqua), Aloe Barbadensis Leaf Juice, Cocamidopropyl Betaine, Decyl ... Lavender and Vanillin will refresh your senses ... Lavender and Vanillin will refresh your senses ...
A second experiment examined effects and interactions among AA, urea and ensiling treatments on composition and in situ ... Apparent total tract digestibilities of vanillin, PCA and FA were greater (P $$.05) when steers were fed ad libitum. Neutral ...
Almost 90% of the vanillin was lost in PG indicating strong reactivity of the phenolic aldehyde in PG. Compared to vanillin, ... The primary goal of this paper is to raise the awareness of potential interactions among flavor solvents and aroma compounds ... 14.6%) and vanillin showed greater losses in anhydrous ethanol than in acidified anhydrous ethanol (24.6% vs. 4.3%). These two ... From T-2 one can also see that the carbonyl compounds (diacetyl and vanillin) were lost in all flavor solvents. ...
Precautions: No serious side effects or drug interactions have been reported to date when used as directed. However, as with ... 40, Vanillin Powder, Polyethylene Glycol 8000, Caramel Color, FD&C Blue Lake No. 1. ...
  • Methods for the analysis of natural vanilla and biosynthetic vanillin have been published. (drugs.com)
  • Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express a mutant AROM polypeptide and/or mutant catechol-O-methyltransferase polypeptide alone or in combination with one or more vanillin biosynthetic enzymes or UDP-glycosyltransferases (UGTs). (justia.com)
  • The crystal structure of the magnesium complex of the o -vanillin thiosemicarbazone ligand 1 is also described. (springer.com)
  • The X-ray structure of NOV1 from Novosphingobium aromaticivorans was determined in complex with its substrate resveratrol (1.89 Å), its product vanillin (1.75 Å), and without any bound ligand (1.61 Å). (pnas.org)
  • 17- Ni-II-Ln(III) complexes with o-vanillin as the main ligand: syntheses, structures, magnetic and magnetocaloric properties. (ehu.es)
  • Cu(ii) and Zn(ii) complexes with a poly-functional ligand derived from o-vanillin and thiophene. (ubu.es)
  • The interaction of a poly-functional ligand derived from o-vanillin and 2-thiophenemethylamine (oVATPNH2) with transition metal ions Cu(II) and Zn(II) leads to the formation of stable coordination compounds, namely [Cu(oVATPNH2)and [Zn(oVATPNH2) (ubu.es)
  • whey protein isolate, WPI) were assessed by (a) quantifying the vanillin unbound to the protein at equilibrium, (b) characterizing the structure of protein-vanillin complexes by fluorescence spectrophotometry, and (c) conducting sensory evaluation. (deepdyve.com)
  • In addition to hydrophobic interactions, antibiotics may sorb to soils via hydrogen bonding, van der Waals forces, cation exchange, cation bridging, and surface complexes [ 4 , 5 ]. (hindawi.com)
  • Crystal Structure, Cytotoxicity and Interaction with DNA of Zinc (II) Complexes with o-Vanillin Schiff Base Ligands. (nih.gov)
  • The results show that complex 1 exhibits higher interaction with CT-DNA than complex 2.In addition, in vitro cytotoxicity of the complexes towards four kinds of cancerous cell lines (A549, HeLa, HL-60 and K562) were assayed by the MTT method.Investigations on the structures indicated that the chirality and nuclearity of zinc complexes play an important role on cytotoxic activity. (nih.gov)
  • Two new zinc complexes, Zn(HL1)2 (1) and [Zn2(H2L2)(OAc) (2) [H2L1 = Schiff base derived from o-vanillin and (R)-(+)-2-amino-3-phenyl-1-propanol, H3L2 = Schiff base derived from o-vanillin and 2-amino-2-ethyl-1,3-propanediol], have been synthesized and characterized by single crystal X-ray diffraction, elemental analyses, TG analyses, solid fluorescence, IR, UV-Vis and circular dichroism spectra. (nih.gov)
  • The interactions of two complexes with calf thymus DNA (CT-DNA) are investigated using UV-Vis, CD and fluorescence spectroscopy. (nih.gov)
  • Solid inclusion complexes of vanillin with cyclodextrins: their formation, characterization, and high-temperature stability. (semanticscholar.org)
  • This study reports the formation of solid vanillin/cyclodextrin inclusion complexes (vanillin/CD ICs) with the aim to enhance the thermal stability and sustained release of vanillin by inclusion complexation. (semanticscholar.org)
  • article{Kayaci2011SolidIC, title={Solid inclusion complexes of vanillin with cyclodextrins: their formation, characterization, and high-temperature stability. (semanticscholar.org)
  • Vanillin is one of the world's most important flavor compounds with a global market of 180 million dollars. (justia.com)
  • The use of Galleria mellonella larvae as preclinical in vivo model system to study host-pathogen interactions, virulence, toxicity and the efficacy of novel compounds is gaining momentum and interest in both the academic and pharmaceutical research space. (criver.com)
  • According to Kaur and Chakraborty [ 11 ], vanillin can be synthesized from a wide range of compounds such as eugenol, glucose, tyrosine, capsaicin, isoeugenol etc. by applying different fungi, bacteria, plant cell or genetically engineered microorganism etc. (biomedcentral.com)
  • The well-known Maillard reaction results from an interaction between amino compounds, usually amino acids or proteins, and reducing carbohydrates (1). (scribd.com)
  • The organic compounds vanillin and isovanillin, for example, smell differently but are two similarly shaped arrangements of the same molecule. (newscientist.com)
  • Vanillin is one of the most important aromatic flavour compounds used in the food and cosmetic industries. (biomedcentral.com)
  • This extends our sub-second response from VOCs to a wide range of compounds in the intermediate-volatility range (IVOCs, e.g. 2-tridecanone and vanillin) and even reduces the response of semi-volatile species (SVOC) like cis-pinonic acid to single-digit seconds. (ionicon.com)
  • On the contrary, the biological activity of essential oils appeared complex, suggesting interactions between individual compounds and the insect under study. (biomedcentral.com)
  • The obtained DLmenthol-based eutectic mixtures were analyzed using NMR and FTIR spectroscopy in order to check their structures and purities and to confirm the interaction of the two compounds leading to the eutectic formation. (unl.pt)
  • Therefore, the potential renal protective effects of orthovanillin (OV), an inhibitor of TLR2, were investigated in the present study in vitro and in vivo. (spandidos-publications.com)
  • Both vanillin and its derivative HMATD act as effective inhibitors for copper in HNO3 (0.5, 1, and 1.5 M) at different temperatures (30, 35, and 40 °C). At room temperature, HMATD was found to be a more effective inhibitor than vanillin, whereas at higher temperatures, vanillin was found to be more effective. (deepdyve.com)
  • The quality of the vanilla bean is not dependent on the vanillin content even though vanillin is associated with the characteristic fragrance of the plant. (drugs.com)
  • Vanilla beans contain approximately 1% to 2% vanillin (4-hydroxy-3-methoxybenzaldehyde), the major flavor component. (drugs.com)
  • Because synthetically-produced vanillin can be obtained inexpensively, it is often used as a substitute or adulterant for natural vanilla extract. (drugs.com)
  • Antibacterial and antifungal actions have been demonstrated in vitro for vanilla and vanillin, suggesting a role in food preservation. (drugs.com)
  • Production of 1 kilogram (kg) of vanillin requires approximately 500 kg of vanilla pods, corresponding to pollination of approximately 40,000 flowers. (justia.com)
  • Vanillin is an aromatic aldehyde, which is contained as a natural product mainly in vanilla (Orchidaceae), benzoin (Styracaceae), and Peruvian balsam (Leguminosae). (freethesaurus.com)
  • Vanillin (4-hydroxy-3-methoxybenzaldehyde) is the major organoleptic component of vanilla flavour which is extracted from the cured beans of Vanilla planifolia . (biomedcentral.com)
  • The results of the study showed that adding sucrose significantly enhanced the intensity of cherry and vanilla flavors, whereas adding vanillin did not enhanced the sweetness of the beverage or custard. (ebscohost.com)
  • VMA is much more potent in inhibiting 5â�²NUC activity than vanillyl acid (VA). The experimental results obtained are in good agreement with the in silico molecular docking interaction data. (uni-mysore.ac.in)
  • 5) Vanillin production from woody biomass by complex−peroxide reaction accelerated by microwave. (kyoto-u.ac.jp)
  • The resting cells could be reused up to four times maintaining the production yield levels over 50%, thus increasing three times the vanillin obtained per gram of biomass. (biomedcentral.com)
  • Optimization of culture conditions and bioconversion parameters, together with the reuse of the biomass, leaded to a final production of 2.52 g of vanillin per liter of culture, which is the highest found in the literature for recombinant strains and the highest achieved so far applying such strains under resting cells conditions. (biomedcentral.com)
  • http://link.springer.com/article/10.1007/s11064-011 -0597-9) Vanillin and 4-hydroxybenzyl alcohol promotes cell proliferation and neuroblast differentiation in the dentate gyrus of mice. (fav-store.net)
  • In this work we studied terpenes (α-pinene, bisabolol, β-elemene, (R)-limonene, (S)-limonene, myrcene, sabinene), which are the main constituents of essential oil obtained from Mutellina purpurea L., a plant with described antitubercular activity, to investigate their interactions with antibiotics against reference Mtb strains and multidrug-resistant clinical isolates. (readbyqxmd.com)
  • Although other G-protein-coupled receptors (GPCRs) recognize biogenic ligands mainly with ionic or hydrogen bonding interactions, ORs recognize odorants mostly via hydrophobic and van der Waals interactions. (jneurosci.org)
  • Nanoparticles, nanofibers, and nanofilms are design and prepared using polymer-polymer interactions, such as van der Waals and electrostatic interactions. (naist.jp)
  • It was reported that sulfonamide antibiotics exhibit strong nonlinear sorption to functional groups of SOM through preferred site-specific sorption via hydrogen bonds and van der Waals interactions. (hindawi.com)
  • The flavor intensity perception results obtained by the sensory evaluation of high protein cookies were well correlated with those predicted by Klotz plots of unbound vanillin. (deepdyve.com)
  • Correlating analytical data with consumers' perception contributes to the understanding of protein/flavor interactions in foods. (deepdyve.com)
  • A recent large-scale study, profiling almost 3,000 dose-resolved drug combinations or antibiotics, human targeted drugs and food additives (such as vanillin) was assessed against 3 ESKAPE pathogens, E. coli , Pseudomonas aeruginosa and Salmonella enterica Serovar Typhimurium 1 . (criver.com)
  • This study highlighted that antagonistic interactions that occur between drugs targeting different cellular processes are far more prevalent when compared to those exhibiting synergistic interactions, seen when the drugs target the same pathway 5 . (criver.com)
  • The Kyoto Encyclopedia of Genes and Genomes pathway analysis and the real-time quantitative PCR results suggest that the calcium signal system and WRKY transcription factor in the plant-pathogen interaction pathway may play an important role in the response process, and all of the WRKY transcription factor genes were divided into three different types. (pubmedcentralcanada.ca)
  • Sorption to the oligomer indicated that in addition to π - π interactions with aromatics phenolic, aldehyde and methoxyl moieties of the oligomer are specific binding sites. (hindawi.com)
  • Joseph, Abraham 2013-06-05 00:00:00 The interaction and corrosion protection properties of vanillin and one of its derivatives, HMATD, on copper in nitric acid (0.5, 1, and 1.5 M) at different temperatures have been studied by polarization, electrochemical impedance spectroscopy, adsorption, surface studies, and computational calculations. (deepdyve.com)
  • From spectroscopic and pH measurements, it is evident that vanillin has undergone a chemical change at higher temperatures in the presence of HNO3. (deepdyve.com)
  • The focus was on adsorption isotherms of vanillin at different temperatures, and these fit well into the Freundlich adsorption isotherm. (pku.edu.cn)
  • In-vitro studies carried out with lung, bladder, kidney medulla, and intestinal microsomes obtained from both animals and man, in the presence of hydrogen - peroxide (7722841) or arachidonic-acid (506321), supported the interaction of BHT and BHA. (cdc.gov)
  • The hydrophobic PDVB in the PDVB/PAEM IPN resin adsorbs through hydrophobic interaction while the hydrophilic PAEM adsorbs by hydrogen bonding. (pku.edu.cn)
  • The antioxidant capacity was measured by different methods, including electron transfer and hydrogen atom transfer-based mechanisms, and total phenolic and flavan-3-ol contents were carried out by Folin-Ciocalteu and Vanillin assays. (mdpi.com)
  • The 2-D sheet supramolecular structure was formed by intermolecular hydrogen bonding interaction. (nih.gov)
  • Since chelation may represent a mode of action of such class of molecules, we studied the interaction of two of them, one with and one without biological activity versus the PA enzyme, towards Mg 2+ , the ion that is probably involved in the endonuclease activity of the heterotrimeric influenza polymerase complex. (springer.com)
  • Interaction study of small molecules with DNA attracts attention for importance in cancer therapy and molecular biology [ 8 ]. (hindawi.com)
  • 2, x, y+1, z) are found to help to construct a homochiral 3D supramolecular architecture (Fig 4b), all the C-H···π, O-H···O and C-H···O interactions observed in complex 1 could be considered as the key factor to transmit chiral information form single molecules to the homochiral 3D supramolecular architecture and yield the chiral crystals finally. (nih.gov)
  • Although the vanillin constituent is often used in bulk food preparation, it cannot be readily substituted for the natural extract when the delicate fragrance of the pure extractive is desired. (drugs.com)
  • Therefore, product formulators must be cognizant of their target audience, as well as aware of fragrance allergens, approved fragrance materials and interactions between fragrances and other ingredients. (cosmeticsandtoiletries.com)
  • In this laboratory, high-performance polymers and functional polymers are prepared by various approaches such as molecular design, polymer structure control, and effective polymer-polymer interaction. (naist.jp)
  • Molecular mechanics (MM+) computational modeling using a DOM-trimer model confirmed that H-bonding and dipole-dipole interactions are crucial for entrapment of sulfonamides in voids of organic matter. (hindawi.com)
  • en 2011 medicine wikipedia what is the molecular mass of. (modeway.tk)
  • The higher vanillin production yield was obtained using resting cells of E. coli strain JM109 harbouring a low-copy number vector and a promoter exhibiting a low activity to drive the expression of the catabolic genes. (biomedcentral.com)
  • Pulping waste can be used as a bio-derived source of industrial solvents, livestock feed, lubricants, consumer products (such as artificial vanillin) and medicines. (gradireland.com)
  • Finally, taking advantage of their hydrophobic character, namely the formation of two phases with water at room temperature, four different biomolecules, caffeine, tryptophan, isophthalic acid, and vanillin, were extracted and the extraction efficiencies of the prepared eutectic solvents compared. (unl.pt)
  • Divanillin is the homodimer of vanillin and used as a taste enhancer compound and also a promissory anticancer drug. (unesp.br)
  • The results show that complex 1 exhibits higher interaction with CT-DNA than complex 2. (nih.gov)
  • Understanding the complex interactions between the different ingredients - along with the latest ingredient innovations and processing techniques - means formulation challenges can be identified and resolved quickly. (solvay.com)
  • Tests were carried out to determine the toxic outcome of the interactions between butylated-hydroxytoluene (128370) (BHT) and a variety of other phenolic derivatives by investigating the in-vitro generation of BHT-quinone-methide in the presence of peroxidase enzymes, the effects of phenols on this reaction, and its in-vivo significance. (cdc.gov)
  • In mice, increased survival in hypoxic conditions and a decrease in the percentage of sickle cells was shown, while in a small clinical study, vanillin 1 g daily produced measurable antisickling effects. (drugs.com)
  • In a study in sickle cell disease, vanillin 1 g daily was given in divided doses over 40 days. (drugs.com)
  • This study showed colistin-clarithromycin and spectinomycin-vanillin to display synergistic activities against E. coli and K. pneumoniae infected G. mellonella , with the drug combinations showing an increase in larval survival over a 72-hour infection, when compared to the administration of each drug alone 1 . (criver.com)
  • The article comments on a study related to the interaction between retronasal olfaction and taste by Barry Green and colleagues, published online in July 2011 in the journal "Chemical Senses. (ebscohost.com)
  • The toxicological implications of the interaction of butylated hydroxytoluene with other antioxidants and phenolic chemicals. (cdc.gov)
  • Vanillin content differs with the variety of the bean, with Bourbon beans containing higher amounts than Mexican and Tahitian beans. (drugs.com)
  • The current paradigm of OR-odorant interactions is based on studies of a limited number of ORs that have been functionally matched with their cognate ligands. (jneurosci.org)