Introduction of substances into the body using a needle and syringe.
Forceful administration into a muscle of liquid medication, nutrient, or other fluid through a hollow needle piercing the muscle and any tissue covering it.
Injections made into a vein for therapeutic or experimental purposes.
Injections introduced directly into localized lesions.
Forceful administration under the skin of liquid medication, nutrient, or other fluid through a hollow needle piercing the skin.
Methods of delivering drugs into a joint space.
Forceful administration into the peritoneal cavity of liquid medication, nutrient, or other fluid through a hollow needle piercing the abdominal wall.
The forcing into the skin of liquid medication, nutrient, or other fluid through a hollow needle, piercing the top skin layer.
The injection of drugs, most often analgesics, into the spinal canal without puncturing the dura mater.
Injections into the cerebral ventricles.
Delivery of drugs into an artery.
The administration of substances into the VITREOUS BODY of the eye with a hypodermic syringe.
Introduction of therapeutic agents into the spinal region using a needle and syringe.
The injection of solutions into the skin by compressed air devices so that only the solution pierces the skin.
The administration of substances into the eye with a hypodermic syringe.
Elements of limited time intervals, contributing to particular results or situations.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
The analysis of a chemical substance by inserting a sample into a carrier stream of reagent using a sample injection valve that propels the sample downstream where mixing occurs in a coiled tube, then passes into a flow-through detector and a recorder or other data handling device.
The injection of very small amounts of fluid, often with the aid of a microscope and microsyringes.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Abuse, overuse, or misuse of a substance by its injection into a vein.
An assisted fertilization technique consisting of the microinjection of a single viable sperm into an extracted ovum. It is used principally to overcome low sperm count, low sperm motility, inability of sperm to penetrate the egg, or other conditions related to male infertility (INFERTILITY, MALE).
Instruments used for injecting or withdrawing fluids. (Stedman, 25th ed)
The relationship between the dose of an administered drug and the response of the organism to the drug.
Sharp instruments used for puncturing or suturing.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
The transparent, semigelatinous substance that fills the cavity behind the CRYSTALLINE LENS of the EYE and in front of the RETINA. It is contained in a thin hyaloid membrane and forms about four fifths of the optic globe.
An esterified form of TRIAMCINOLONE. It is an anti-inflammatory glucocorticoid used topically in the treatment of various skin disorders. Intralesional, intramuscular, and intra-articular injections are also administered under certain conditions.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
A glucocorticoid given, as the free alcohol or in esterified form, orally, intramuscularly, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. (From Martindale, The Extra Pharmacopoeia, 30th ed, p739)
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.
Drugs used for their actions on skeletal muscle. Included are agents that act directly on skeletal muscle, those that alter neuromuscular transmission (NEUROMUSCULAR BLOCKING AGENTS), and drugs that act centrally as skeletal muscle relaxants (MUSCLE RELAXANTS, CENTRAL). Drugs used in the treatment of movement disorders are ANTI-DYSKINESIA AGENTS.
A serotype of botulinum toxins that has specificity for cleavage of SYNAPTOSOMAL-ASSOCIATED PROTEIN 25.
Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.
A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.
Techniques and strategies which include the use of coding sequences and other conventional or radical means to transform or modify cells for the purpose of treating or reversing disease conditions.
Scales, questionnaires, tests, and other methods used to assess pain severity and duration in patients or experimental animals to aid in diagnosis, therapy, and physiological studies.
Usage of a single needle among two or more people for injecting drugs. Needle sharing is a high-risk behavior for contracting infectious disease.
An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
DNA molecules capable of autonomous replication within a host cell and into which other DNA sequences can be inserted and thus amplified. Many are derived from PLASMIDS; BACTERIOPHAGES; or VIRUSES. They are used for transporting foreign genes into recipient cells. Genetic vectors possess a functional replicator site and contain GENETIC MARKERS to facilitate their selective recognition.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Substances used to allow enhanced visualization of tissues.
Experimental transplantation of neoplasms in laboratory animals for research purposes.
The various ways of administering a drug or other chemical to a site in a patient or animal from where the chemical is absorbed into the blood and delivered to the target tissue.
The introduction of functional (usually cloned) GENES into cells. A variety of techniques and naturally occurring processes are used for the gene transfer such as cell hybridization, LIPOSOMES or microcell-mediated gene transfer, ELECTROPORATION, chromosome-mediated gene transfer, TRANSFECTION, and GENETIC TRANSDUCTION. Gene transfer may result in genetically transformed cells and individual organisms.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
An encapsulated lymphatic organ through which venous blood filters.
The observable response an animal makes to any situation.
A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.
Drugs used in the treatment of movement disorders. Most of these act centrally on dopaminergic or cholinergic systems. Among the most important clinically are those used for the treatment of Parkinson disease (ANTIPARKINSON AGENTS) and those for the tardive dyskinesias.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations, or by parent x offspring matings carried out with certain restrictions. All animals within an inbred strain trace back to a common ancestor in the twentieth generation.
Mutant mice homozygous for the recessive gene "nude" which fail to develop a thymus. They are useful in tumor studies and studies on immune responses.
Compounds that are used in medicine as sources of radiation for radiotherapy and for diagnostic purposes. They have numerous uses in research and industry. (Martindale, The Extra Pharmacopoeia, 30th ed, p1161)
The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Female germ cells derived from OOGONIA and termed OOCYTES when they enter MEIOSIS. The primary oocytes begin meiosis but are arrested at the diplotene state until OVULATION at PUBERTY to give rise to haploid secondary oocytes or ova (OVUM).
People who take drugs for a non-therapeutic or non-medical effect. The drugs may be legal or illegal, but their use often results in adverse medical, legal, or social consequences for the users.
Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)
Unstable isotopes of iodine that decay or disintegrate emitting radiation. I atoms with atomic weights 117-139, except I 127, are radioactive iodine isotopes.
Apparatus, devices, or supplies intended for one-time or temporary use.
A family of non-enveloped viruses infecting mammals (MASTADENOVIRUS) and birds (AVIADENOVIRUS) or both (ATADENOVIRUS). Infections may be asymptomatic or result in a variety of diseases.
Refers to animals in the period of time just after birth.
An antigen solution emulsified in mineral oil. The complete form is made up of killed, dried mycobacteria, usually M. tuberculosis, suspended in the oil phase. It is effective in stimulating cell-mediated immunity (IMMUNITY, CELLULAR) and potentiates the production of certain IMMUNOGLOBULINS in some animals. The incomplete form does not contain mycobacteria.
An increased sensation of pain or discomfort produced by mimimally noxious stimuli due to damage to soft tissue containing NOCICEPTORS or injury to a peripheral nerve.
Substances that reduce or suppress INFLAMMATION.
Viscoelastic solutions that are injected into JOINTS in order to alleviate symptoms of joint-related disorders such as OSTEOARTHRITIS.
Antibodies produced by a single clone of cells.
Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.
A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.
Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms.
Proteins prepared by recombinant DNA technology.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS.
Organized services for exchange of sterile needles and syringes used for injections as a potential means of reducing the transmission of infectious diseases.
A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Luteinizing hormone regulates steroid production by the interstitial cells of the TESTIS and the OVARY. The preovulatory LUTEINIZING HORMONE surge in females induces OVULATION, and subsequent LUTEINIZATION of the follicle. LUTEINIZING HORMONE consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH and FSH), but the beta subunit is unique and confers its biological specificity.
The measure of the level of heat of a human or animal.
Interruption of NEURAL CONDUCTION in peripheral nerves or nerve trunks by the injection of a local anesthetic agent (e.g., LIDOCAINE; PHENOL; BOTULINUM TOXINS) to manage or treat pain.
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
An assisted reproductive technique that includes the direct handling and manipulation of oocytes and sperm to achieve fertilization in vitro.
The making of a radiograph of an object or tissue by recording on a photographic plate the radiation emitted by radioactive material within the object. (Dorland, 27th ed)
Chemical agents injected into blood vessels and lymphatic sinuses to shrink or cause localized THROMBOSIS; FIBROSIS, and obliteration of the vessels. This treatment is applied in a number of conditions such as VARICOSE VEINS; HEMORRHOIDS; GASTRIC VARICES; ESOPHAGEAL VARICES; PEPTIC ULCER HEMORRHAGE.
The 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids.
The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
Volume of biological fluid completely cleared of drug metabolites as measured in unit time. Elimination occurs as a result of metabolic processes in the kidney, liver, saliva, sweat, intestine, heart, brain, or other site.
A water-soluble extractive mixture of sulfated polysaccharides from RED ALGAE. Chief sources are the Irish moss CHONDRUS CRISPUS (Carrageen), and Gigartina stellata. It is used as a stabilizer, for suspending COCOA in chocolate manufacture, and to clarify BEVERAGES.
The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)
Injections into the lymph nodes or the lymphatic system.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
A genus of the family PARVOVIRIDAE, subfamily PARVOVIRINAE, which are dependent on a coinfection with helper adenoviruses or herpesviruses for their efficient replication. The type species is Adeno-associated virus 2.
Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
Compounds capable of relieving pain without the loss of CONSCIOUSNESS.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
One of three principal openings in the SUBARACHNOID SPACE. They are also known as cerebellomedullary cistern, and collectively as cisterns.
Further or repeated use of equipment, instruments, devices, or materials. It includes additional use regardless of the original intent of the producer as to disposability or durability. It does not include the repeated use of fluids or solutions.
Deliberate stimulation of the host's immune response. ACTIVE IMMUNIZATION involves administration of ANTIGENS or IMMUNOLOGIC ADJUVANTS. PASSIVE IMMUNIZATION involves administration of IMMUNE SERA or LYMPHOCYTES or their extracts (e.g., transfer factor, immune RNA) or transplantation of immunocompetent cell producing tissue (thymus or bone marrow).
The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent.
Ventral part of the DIENCEPHALON extending from the region of the OPTIC CHIASM to the caudal border of the MAMMILLARY BODIES and forming the inferior and lateral walls of the THIRD VENTRICLE.
The principal alkaloid in opium and the prototype opiate analgesic and narcotic. Morphine has widespread effects in the central nervous system and on smooth muscle.
A PREDNISOLONE derivative with similar anti-inflammatory action.
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
A blocking of nerve conduction to a specific area by an injection of an anesthetic agent.
The number of CELLS of a specific kind, usually measured per unit volume or area of sample.
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
The measurement of an organ in volume, mass, or heaviness.
The first artificially produced element and a radioactive fission product of URANIUM. Technetium has the atomic symbol Tc, atomic number 43, and atomic weight 98.91. All technetium isotopes are radioactive. Technetium 99m (m=metastable) which is the decay product of Molybdenum 99, has a half-life of about 6 hours and is used diagnostically as a radioactive imaging agent. Technetium 99 which is a decay product of technetium 99m, has a half-life of 210,000 years.
A widely used local anesthetic agent.
Either of two extremities of four-footed non-primate land animals. It usually consists of a FEMUR; TIBIA; and FIBULA; tarsals; METATARSALS; and TOES. (From Storer et al., General Zoology, 6th ed, p73)
The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.
A group of glucose polymers made by certain bacteria. Dextrans are used therapeutically as plasma volume expanders and anticoagulants. They are also commonly used in biological experimentation and in industry for a wide variety of purposes.
Mature male germ cells derived from SPERMATIDS. As spermatids move toward the lumen of the SEMINIFEROUS TUBULES, they undergo extensive structural changes including the loss of cytoplasm, condensation of CHROMATIN into the SPERM HEAD, formation of the ACROSOME cap, the SPERM MIDPIECE and the SPERM TAIL that provides motility.
A decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE. GnRH is produced by neurons in the septum PREOPTIC AREA of the HYPOTHALAMUS and released into the pituitary portal blood, leading to stimulation of GONADOTROPHS in the ANTERIOR PITUITARY GLAND.
Small uniformly-sized spherical particles, of micrometer dimensions, frequently labeled with radioisotopes or various reagents acting as tags or markers.
Four CSF-filled (see CEREBROSPINAL FLUID) cavities within the cerebral hemispheres (LATERAL VENTRICLES), in the midline (THIRD VENTRICLE) and within the PONS and MEDULLA OBLONGATA (FOURTH VENTRICLE).
The physical activity of a human or an animal as a behavioral phenomenon.
Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.
Diabetes mellitus induced experimentally by administration of various diabetogenic agents or by PANCREATECTOMY.
The production of ANTIBODIES by proliferating and differentiated B-LYMPHOCYTES under stimulation by ANTIGENS.
A group of polycyclic compounds closely related biochemically to TERPENES. They include cholesterol, numerous hormones, precursors of certain vitamins, bile acids, alcohols (STEROLS), and certain natural drugs and poisons. Steroids have a common nucleus, a fused, reduced 17-carbon atom ring system, cyclopentanoperhydrophenanthrene. Most steroids also have two methyl groups and an aliphatic side-chain attached to the nucleus. (From Hawley's Condensed Chemical Dictionary, 11th ed)
Toxins closely associated with the living cytoplasm or cell wall of certain microorganisms, which do not readily diffuse into the culture medium, but are released upon lysis of the cells.
The rate dynamics in chemical or physical systems.
Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.
Isotopes that exhibit radioactivity and undergo radioactive decay. (From Grant & Hackh's Chemical Dictionary, 5th ed & McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The time it takes for a substance (drug, radioactive nuclide, or other) to lose half of its pharmacologic, physiologic, or radiologic activity.
Transplantation between animals of different species.
Production of an image when x-rays strike a fluorescent screen.
Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).
Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.
Non-human animals, selected because of specific characteristics, for use in experimental research, teaching, or testing.
An alkylamide found in CAPSICUM that acts at TRPV CATION CHANNELS.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Toxic proteins produced from the species CLOSTRIDIUM BOTULINUM. The toxins are synthesized as a single peptide chain which is processed into a mature protein consisting of a heavy chain and light chain joined via a disulfide bond. The botulinum toxin light chain is a zinc-dependent protease which is released from the heavy chain upon ENDOCYTOSIS into PRESYNAPTIC NERVE ENDINGS. Once inside the cell the botulinum toxin light chain cleaves specific SNARE proteins which are essential for secretion of ACETYLCHOLINE by SYNAPTIC VESICLES. This inhibition of acetylcholine release results in muscular PARALYSIS.
Disease involving a spinal nerve root (see SPINAL NERVE ROOTS) which may result from compression related to INTERVERTEBRAL DISK DISPLACEMENT; SPINAL CORD INJURIES; SPINAL DISEASES; and other conditions. Clinical manifestations include radicular pain, weakness, and sensory loss referable to structures innervated by the involved nerve root.
A specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, delta, and kappa opioid receptors.
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.
A range of methods used to reduce pain and anxiety during dental procedures.
The property of blood capillary ENDOTHELIUM that allows for the selective exchange of substances between the blood and surrounding tissues and through membranous barriers such as the BLOOD-AIR BARRIER; BLOOD-AQUEOUS BARRIER; BLOOD-BRAIN BARRIER; BLOOD-NERVE BARRIER; BLOOD-RETINAL BARRIER; and BLOOD-TESTIS BARRIER. Small lipid-soluble molecules such as carbon dioxide and oxygen move freely by diffusion. Water and water-soluble molecules cannot pass through the endothelial walls and are dependent on microscopic pores. These pores show narrow areas (TIGHT JUNCTIONS) which may limit large molecule movement.
A natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. It is found in the UMBILICAL CORD, in VITREOUS BODY and in SYNOVIAL FLUID. A high urinary level is found in PROGERIA.
The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.
Management, removal, and elimination of biologic, infectious, pathologic, and dental waste. The concept includes blood, mucus, tissue removed at surgery or autopsy, soiled surgical dressings, and other materials requiring special control and handling. Disposal may take place where the waste is generated or elsewhere.
Organic compounds that contain technetium as an integral part of the molecule. These compounds are often used as radionuclide imaging agents.
A polypeptide that is secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Growth hormone, also known as somatotropin, stimulates mitosis, cell differentiation and cell growth. Species-specific growth hormones have been synthesized.
The discharge of an OVUM from a rupturing follicle in the OVARY.
Agents and endogenous substances that antagonize or inhibit the development of new blood vessels.
Chinese herbal or plant extracts which are used as drugs to treat diseases or promote general well-being. The concept does not include synthesized compounds manufactured in China.
The transfer of mammalian embryos from an in vivo or in vitro environment to a suitable host to improve pregnancy or gestational outcome in human or animal. In human fertility treatment programs, preimplantation embryos ranging from the 4-cell stage to the blastocyst stage are transferred to the uterine cavity between 3-5 days after FERTILIZATION IN VITRO.
Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.
The number of times the HEART VENTRICLES contract per unit of time, usually per minute.
They are oval or bean shaped bodies (1 - 30 mm in diameter) located along the lymphatic system.
A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in ALCOHOLIC BEVERAGES.
A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
Mice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity.
A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Follicle-stimulating hormone stimulates GAMETOGENESIS and the supporting cells such as the ovarian GRANULOSA CELLS, the testicular SERTOLI CELLS, and LEYDIG CELLS. FSH consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity.
Use of electric potential or currents to elicit biological responses.
The active sympathomimetic hormone from the ADRENAL MEDULLA. It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. It is used in ASTHMA and CARDIAC FAILURE and to delay absorption of local ANESTHETICS.
Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS.
Chemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS.
Dosage forms of a drug that act over a period of time by controlled-release processes or technology.
Procedures for the improvement or enhancement of the appearance of the visible parts of the body.
Unstable isotopes of indium that decay or disintegrate emitting radiation. In atoms with atomic weights 106-112, 113m, 114, and 116-124 are radioactive indium isotopes.
An enzyme isolated from horseradish which is able to act as an antigen. It is frequently used as a histochemical tracer for light and electron microscopy. Its antigenicity has permitted its use as a combined antigen and marker in experimental immunology.
One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action.
Peripheral AFFERENT NEURONS which are sensitive to injuries or pain, usually caused by extreme thermal exposures, mechanical forces, or other noxious stimuli. Their cell bodies reside in the DORSAL ROOT GANGLIA. Their peripheral terminals (NERVE ENDINGS) innervate target tissues and transduce noxious stimuli via axons to the CENTRAL NERVOUS SYSTEM.
Artificial, single or multilaminar vesicles (made from lecithins or other lipids) that are used for the delivery of a variety of biological molecules or molecular complexes to cells, for example, drug delivery and gene transfer. They are also used to study membranes and membrane proteins.
Glucose in blood.
The period in the ESTROUS CYCLE associated with maximum sexual receptivity and fertility in non-primate female mammals.
A ubiquitous sodium salt that is commonly used to season food.
Systems for the delivery of drugs to target sites of pharmacological actions. Technologies employed include those concerning drug preparation, route of administration, site targeting, metabolism, and toxicity.
A tissue adhesive that is applied as a monomer to moist tissue and polymerizes to form a bond. It is slowly biodegradable and used in all kinds of surgery, including dental.
A class of compounds of the type R-M, where a C atom is joined directly to any other element except H, C, N, O, F, Cl, Br, I, or At. (Grant & Hackh's Chemical Dictionary, 5th ed)
Treatment of varicose veins, hemorrhoids, gastric and esophageal varices, and peptic ulcer hemorrhage by injection or infusion of chemical agents which cause localized thrombosis and eventual fibrosis and obliteration of the vessels.
A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.
Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.
The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)
A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
ARTHRITIS that is induced in experimental animals. Immunological methods and infectious agents can be used to develop experimental arthritis models. These methods include injections of stimulators of the immune response, such as an adjuvant (ADJUVANTS, IMMUNOLOGIC) or COLLAGEN.
A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).
A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.
A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.
Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.
Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.
The lower portion of the BRAIN STEM. It is inferior to the PONS and anterior to the CEREBELLUM. Medulla oblongata serves as a relay station between the brain and the spinal cord, and contains centers for regulating respiratory, vasomotor, cardiac, and reflex activities.
Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.

Mechanisms for generating the autonomous cAMP-dependent protein kinase required for long-term facilitation in Aplysia. (1/3438)

The formation of a persistently active cAMP-dependent protein kinase (PKA) is critical for establishing long-term synaptic facilitation (LTF) in Aplysia. The injection of bovine catalytic (C) subunits into sensory neurons is sufficient to produce protein synthesis-dependent LTF. Early in the LTF induced by serotonin (5-HT), an autonomous PKA is generated through the ubiquitin-proteasome-mediated proteolysis of regulatory (R) subunits. The degradation of R occurs during an early time window and appears to be a key function of proteasomes in LTF. Lactacystin, a specific proteasome inhibitor, blocks the facilitation induced by 5-HT, and this block is rescued by injecting C subunits. R is degraded through an allosteric mechanism requiring an elevation of cAMP coincident with the induction of a ubiquitin carboxy-terminal hydrolase.  (+info)

T cell subsets in experimental lupus nephritis: modulation by bacterial superantigen. (2/3438)

Chronic graft-vs-host disease (GvH), induced by injection of DBA/2 lymphocytes into (C57BL/6 x DBA/2)F1 hybrids, is a murine model for lupus nephritis, associated with a Th2-dependent polyclonal B cell activation. The development of glomerulosclerosis in this model is preceded by a glomerular influx of LFA-1+ T cells. We investigated whether exposure to bacterial superantigen would modulate the course of this autoimmune syndrome. Injection of the bacterial superantigen staphylococcal enterotoxin B (SEB) in mice has been shown to induce the activation of TcRVbeta8+ T cells. Within 2 weeks after GvH induction, mice were injected twice with 20 microg of SEB and the following parameters were examined: cytokine and Ig profile, proteinuria and renal pathology. The second SEB injection induced in GvH mice an increased release of both interferon-gamma (IFN-gamma) and interleukin-10 (IL-10) as compared with control F1 mice. No differences were observed in IL-2 production. SEB-treated GvH mice demonstrated a delayed onset of proteinuria. Histological analysis of the kidney showed that SEB-challenged GvH mice displayed significantly more interstitial inflammation and mesangial proliferation together with more IgG2a deposits in glomeruli than non-injected GvH mice. From these results, we conclude that GvH mice are more responsive to SEB in terms of cytokine production and that bacterial infection can modulate the course of this renal disease from a membranous to a more proliferative type of nephropathy.  (+info)

Embryonic and postnatal injections of bromodeoxyuridine produce age-dependent morphological and behavioral abnormalities. (3/3438)

The mitotic marker 5-bromodeoxyuridine (BrdU) was injected twice daily (60 mg/kg) into pregnant hooded rats on one of embryonic days (E) 11, 12, 13, 15, 17, or 21, or into rat pups on postnatal day (P) 10. The principal findings were the following: (1) BrdU exposure on E11 produces profound effects on body morphology, and animals must be fed a special diet because of chronic tooth abnormalities; (2) BrdU exposure at E17 or earlier produces a change in coat spotting pattern, the precise pattern varying with age; (3) BrdU exposure on E15 or earlier produces a reduction in both brain and body weight; (4) BrdU exposure on E17 or earlier reduces cortical thickness; (5) BrdU exposure on E11-E13 and at P10 reduces cerebellar size relative to cerebral size; (6) spatial learning is significantly affected after injections of BrdU at E11-E17, but the largest effect is on E17; (7) the deficit in spatial learning may be related in part to a reduction in visual acuity; and (8) skilled forelimb ability is most disrupted after BrdU exposure at E15 but is also impaired after injections on E13 or earlier. BrdU thus has teratological effects on body, brain, and behavior that vary with the developmental age of the fetus or infant.  (+info)

Homocysteine enhances neutrophil-endothelial interactions in both cultured human cells and rats In vivo. (4/3438)

Despite intense investigation, mechanisms linking the development of occlusive vascular disease with elevated levels of homocysteine (HCY) are still unclear. The vascular endothelium plays a key role in regulating thrombogenesis and thrombolysis. We hypothesized that vascular lesions in individuals with elevated plasma HCY may be related to a dysfunction of the endothelium triggered by HCY. We investigated the effect of HCY on human neutrophil adhesion to and migration through endothelial monolayers. We also examined the effect of HCY on leukocyte adhesion and migration in mesenteric venules of anesthetized rats. We found that pathophysiological concentrations of HCY in vitro induce increased adhesion between neutrophils and endothelial cells. This contact results in neutrophil migration across the endothelial layer, with concurrent damage and detachment of endothelial cells. In vivo, HCY infused in anesthetized rats caused parallel effects, increasing leukocyte adhesion to and extravasation from mesenteric venules. Our results suggest that extracellular H2O2, generated by adherent neutrophils and/or endothelial cells, is involved in the in vitro endothelial cell damage. The possibility exists that leukocyte-mediated changes in endothelial integrity and function may lead to the vascular disease seen in individuals with elevated plasma HCY.  (+info)

Riluzole improves functional recovery after ischemia in the rat retina. (5/3438)

PURPOSE: Retinal ischemia leads to neuronal death. The effects of riluzole, a drug that protects against the deleterious effect of cerebral ischemia by acting on several types of ion channels and blocking glutamatergic neurotransmission, were investigated in a rat model of retinal ischemic injury. METHODS: Retinal ischemia was induced by increasing intraocular pressure above systolic blood pressure for 30 minutes. Electroretinograms were recorded before ischemia and at different periods of reperfusion. Riluzole was injected or topically applied to the eye before or after ischemia and twice daily during the reperfusion period. Retinas were harvested for histopathology (toluidine blue and silver-impregnation stainings, Tdt-dUTP terminal nick-end labeling [TUNEL] method) and immunohistochemistry for cytoskeletal glial fibrillary acid protein and c-jun NH2-terminal kinase (p-JNK). RESULTS: Ischemia for 30 minutes caused a reduction of a- and b-waves of the electroretinogram. Systemic and topical treatments with riluzole significantly enhanced the recovery of the reduced a- and b-waves after defined reperfusion times. Riluzole also prevented or attenuated ischemia-induced retinal cell death (necrosis and apoptosis) and reduced the activation of p-JNK, c-jun phosphorylation, and the increase of cytoskeletal proteins induced by ischemic injury. CONCLUSIONS: Riluzole acted in vivo as a potent neuroprotective agent against pressure-induced ischemia. Therefore, riluzole may be a major drug for use in protection against retinal injury.  (+info)

CNTF, not other trophic factors, promotes axonal regeneration of axotomized retinal ganglion cells in adult hamsters. (6/3438)

PURPOSE: To investigate the in vivo effects of trophic factors on the axonal regeneration of axotomized retinal ganglion cells in adult hamsters. METHODS: The left optic nerve was transected intracranially or intraorbitally, and a peripheral nerve graft was apposed or sutured to the axotomized optic nerve to enhance regeneration. Trophic factors were applied intravitreally every 5 days. Animals were allowed to survive for 3 or 4 weeks. Regenerating retinal ganglion cells (RGCs) were labeled by applying the dye Fluoro-Gold to the distal end of the peripheral nerve graft 3 days before the animals were killed. RESULTS: Intravitreal application of ciliary neurotrophic factor substantially enhanced the regeneration of damaged axons into a sciatic nerve graft in both experimental conditions (intracranial and intraorbital optic nerve transections) but did not increase the survival of distally axotomized RGCs. Basic fibroblast growth factor and neurotrophins such as nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 failed to enhance axonal regeneration of distally axotomized RGCs. CONCLUSIONS: Neurons of the adult central nervous system can regenerate in response to trophic supply after injury, and ciliary neurotrophic factor is at least one of the trophic factors that can promote axonal regeneration of axotomized RGCs.  (+info)

Effect of the cannabinoid receptor agonist WIN55212-2 on sympathetic cardiovascular regulation. (7/3438)

1. The aim of the present study was to analyse the cardiovascular actions of the synthetic CB1/CB2 cannabinoid receptor agonist WIN55212-2, and specifically to determine its sites of action on sympathetic cardiovascular regulation. 2. Pithed rabbits in which the sympathetic outflow was continuously stimulated electrically or which received a pressor infusion of noradrenaline were used to study peripheral prejunctional and direct vascular effects, respectively. For studying effects on brain stem cardiovascular regulatory centres, drugs were administered into the cisterna cerebellomedullaris in conscious rabbits. Overall cardiovascular effects of the cannabinoid were studied in conscious rabbits with intravenous drug administration. 3. In pithed rabbits in which the sympathetic outflow was continuously electrically stimulated, intravenous injection of WIN55212-2 (5, 50 and 500 microg kg(-1)) markedly reduced blood pressure, the spillover of noradrenaline into plasma and the plasma noradrenaline concentration, and these effects were antagonized by the CB1 cannabinoid receptor-selective antagonist SR141716A. The hypotensive and the sympathoinhibitory effect of WIN55212-2 was shared by CP55940, another mixed CB1/CB2 cannabinoid receptor agonist, but not by WIN55212-3, the enantiomer of WIN55212-2, which lacks affinity for cannabinoid binding sites. WIN55212-2 had no effect on vascular tone established by infusion of noradrenaline in pithed rabbits. 4. Intracisternal application of WIN55212-2 (0.1, 1 and 10 microg kg(-1)) in conscious rabbits increased blood pressure and the plasma noradrenaline concentration and elicited bradycardia; this latter effect was antagonized by atropine. 5. In conscious animals, intravenous injection of WIN55212-2 (5 and 50 microg kg(-1)) caused bradycardia, slight hypotension, no change in the plasma noradrenaline concentration, and an increase in renal sympathetic nerve firing. The highest dose of WIN55212-2 (500 microg kg(-1)) elicited hypotension and tachycardia, and sympathetic nerve activity and the plasma noradrenaline concentration declined. 6. The results obtained in pithed rabbits indicate that activation of CB1 cannabinoid receptors leads to marked peripheral prejunctional inhibition of noradrenaline release from postganglionic sympathetic axons. Intracisternal application of WIN55212-2 uncovered two effects on brain stem cardiovascular centres: sympathoexcitation and activation of cardiac vagal fibres. The highest dose of systemically administered WIN55212-2 produced central sympathoinhibition; the primary site of this action is not known.  (+info)

Microbiological and inflammatory effects of murine recombinant interleukin-10 in two models of polymicrobial peritonitis in rats. (8/3438)

A protective effect of interleukin-10 (IL-10) against the development of lethal shock has been demonstrated in various animal models. In contrast, the immunosuppressant properties of this mediator have been minimally evaluated in low-mortality models of infections. The clinical, microbiological, and inflammatory effects of murine recombinant IL-10 (mrIL-10) therapy were evaluated in two models of peritonitis in rats, which differed in the degree of severity of peritoneal inflammation 3 days after inoculation of Escherichia coli and Bacteroides fragilis with or without Enterococcus faecalis. The severity of the disease remained unchanged compared to that in control animals. A dose-related decrease in the peritoneal phagocyte count was observed in the treated groups compared to the counts in control animals. The subsequent experiments were performed exclusively in the mixed gram-positive-gram negative model, which exhibits an intense and prolonged inflammatory response with similar criteria. The early effects of mrIL-10 (evaluated 6 h after inoculation), repeated injections of mrIL-10 (four doses injected from 0 to 9 h after bacterial challenge), and pretreatment (two doses injected 6 and 3 h before inoculation) were evaluated. The clinical and microbiological parameters remained unchanged in the treated animals. Decreases in the peritoneal phagocyte count and the peritoneal concentration of tumor necrosis factor were observed following repeated injections of mrIL-10. In summary, our data suggest that mrIL-10 does not worsen the manifestations of sepsis. However, these results need to be confirmed in clinical practice.  (+info)

Caudal steroid injection procedure is performed to relieve low back and radiating leg pain. Many patients feel relief from only one or two injections.
Nitrocin 50 MG Injection is an effective medicine to prevent and treat chest pain (angina). Angina is caused due to the narrowing of blood vessels that carries blood to the heart muscle. It is used in various forms viz. sublingual tablets, patches, sprays, injections. Buy Nitrocin 50 MG Injection Online. Know uses, side effects, dosage, contraindications, substitutes, benefit, interactions, purpose, drug interactions, precautions, warnings etc. Download Practo app & get your medicines home delivered.
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TY - JOUR. T1 - Ocular tolerability and efficacy of intravitreal and subconjunctival injections of sirolimus in patients with non-infectious uveitis. T2 - Primary 6-month results of the SAVE Study. AU - Nguyen, Quan Dong. AU - Ibrahim, Mohamed A.. AU - Watters, Anthony. AU - Bittencourt, Millena. AU - Yohannan, Jithin. AU - Sepah, Yasir J.. AU - Dunn, James P.. AU - Naor, Joel. AU - Shams, Naveed. AU - Shaikh, Ovais. AU - Leder, Henry Alexander. AU - Do, Diana V.. PY - 2013/12/1. Y1 - 2013/12/1. N2 - Background: The purpose of this study is to evaluate the ocular tolerability and efficacy of sirolimus administered as subconjunctival or intravitreal injections in patients with non-infectious uveitis. Sirolimus as a Therapeutic Approach for Uveitis (SAVE) is a prospective, randomized, open-label, interventional study. Thirty patients were enrolled and randomized in 1:1 ratio to receive either intravitreal injections of 352 μg sirolimus or subconjunctival injections of 1,320 μg at days 0, 60, and ...
The present article provides experimental evidence that direct intramyocardial injection of BM cells can induce a serious high frequency of and critical types of ventricular arrhythmias for the initial 14 days after injection in post-MI chronic HF. Such arrhythmia did not occur after retrograde intracoronary injection of BM cells, despite the fact that the 2 injection methods resulted in similar therapeutic benefits and similar graft sizes. These data have important implications in developing the optimal protocol for cell therapy using BM cells.. Arrhythmogenicity of intramyocardial injection of BM cells has not been discussed extensively, probably because previous clinical trials have reported negative results.5,8,9 However, the patients studied in these trials were medically treated with drugs having an antiarrhythmic effect such as β-blocker, which would have masked the arrhythmogenicity. In addition, for detecting arrhythmias, these studies monitored patients only for ,2 days after cell ...
Aim: To determine if pre-injection diffusion of local anaesthetic solution influences the discomfort of needle penetration in the palate. Methods: A placebo-controlled, randomised, doubleblind split-mouth investigation was conducted. 25...
Middle East & Africa: GCC Countries and Rest of Middle East & Africa. Segmenting the market into smaller components helps in analyzing the dynamics of the market with more clarity. Another key component that is included in the report is the regional analysis to assess the global presence of the Sterile Injectable Drugs market. You can also opt for a yearly subscription of all the updates on the Sterile Injectable Drugs market.. Request a sample before buying this report @ https://dataintelo.com/request-sample/?reportId=74673. Below is the TOC of the report:. Executive Summary. Assumptions and Acronyms Used. Research Methodology. Sterile Injectable Drugs Market Overview. Sterile Injectable Drugs Supply Chain Analysis. Sterile Injectable Drugs Pricing Analysis. Global Sterile Injectable Drugs Market Analysis and Forecast by Type. Global Sterile Injectable Drugs Market Analysis and Forecast by Application. Global Sterile Injectable Drugs Market Analysis and Forecast by Sales Channel. Global Sterile ...
Aims: To evaluate the effects of intravitreal injection of preservative-free triamcinolone acetonide (PFTA) and TA containing preservative (KE).. Methods: A retrospective review was conducted of 646 intravitreal 4 mg/0.1 ml steroid injections in 471 eyes. A total of 577 intravitreal injections of PFTA and 69 injections of KE were administered in non-randomised eyes. No supernatant removal from KE was performed. Non-infectious endophthalmitis was defined as pseudohypopyon/hypopyon with or without an inflammatory reaction that regressed after steroid eye drop instillation. Ocular hypertension was defined as more than 23 mm Hg with Goldman applanation tonometry. Patients were followed and examined 1, 7 and 28 days, and 3, 4, 6 and 12 months after injection and annually thereafter. Statistical analysis was performed using Fishers exact test and Χ2 test. p Values ,0.05 were considered significant.. Results: Both groups did not differ in demographics (p,0.05). Follow-up ranged from 6 to 57 months ...
A dry supplement injection system and method for fertigation of crops, and a micronized supplement for use in the dry supplement injection system to fertilize the crops. The injection system is connectable to a water supply to produce a slurry with the supplement which is continuously introduced into a flow of irrigation water for watering the crops. The injection system includes a hopper having a cylindrical upper portion having a supplement inlet opening and a tapered lower portion terminating at a slurry outlet opening. A perforated funnel assembly is disposed within the hopper that includes an inverted, perforated funnel with a vertically disposed inlet pipe that extends through an upper opening of the funnel and which is clamped to the funnel, with a spray nozzle connected to a lower end of the inlet pipe to spray water onto an inner surface of the funnel. An inlet water pipe system includes a main pipe that connects to the water source through an outer wall of the hopper to the inlet pipe and the
Enquire about the report: Global Injectable Drug Delivery Market - Industry Trends and Forecast to 2024. Table of Content:. 1. INTRODUCTION. 1.1. OVERVIEW OF THE INJECTABLE DRUG DELIVERY MARKET. 1.2. MARKET SEGMENTATION & COVERAGE. 1.2.1. CURRENCY AND PRICING. 1.2.2. LIMITATION. 1.2.3. STAKEHOLDERS. 2. RESEARCH METHODOLOGY. 2.1. KEY TAKEAWAYS. 2.2. ARRIVING AT THE INJECTABLE DRUG DELIVERY MARKET SIZE. 2.2.1. MARKET CRACKDOWN APPROACH. 2.2.2. COMPANY REVENUE AND MARKET SHARE ANALYSIS. 2.2.3. DATA TRIANGULATION. 2.2.4. KEY DATA POINTS FROM PRIMARY SOURCES. 2.2.5. KEY DATA POINTS FROM SECONDARY SOURCES. 2.2.6. PORTERS FIVE FORCES MATRIX. 2.3. GLOBAL INJECTABLE DRUG DELIVERY MARKET: RESEARCH SNAPSHOT. 2.4. ASSUMPTIONS. 3. MARKET LANDSCAPE SUMMARY. 4. PREMIUM INSIGHTS. 4.1. OVERVIEW. 4.2. INJECTABLE DRUG DELIVERY MARKET: KEY PRIMARY INSIGHTS. 4.3. MARKET OVERVIEW. 4.3.1. DRIVERS. 4.3.1.1. RISING PREVALENCE OF CHRONIC DISEASES. 4.3.1.2. INCRESING DEMAND OF SELF INJECTION DEVICES. 4.3.1.3. GROWTH OF ...
Injectable drug delivery is defined as administration of a drug or drugs directly into patients blood circulationthrough a delivery device. It is considered as the most common and effective route of administration of most therapeutic agents to achieve the desired quick response. The injectable route of drug administration is expected to continue to be an important delivery system. This has been attributed to reasons that injectable drug delivery system allows administration of drugs with poor oral bioavailability, delivery of the drug at the site of action, targeted drug delivery system. Reduction in the number of injection is achieved by various technologies such as controlled release, targeted delivery and needle free delivery thus overcoming the problems associated with conventional injectable drug delivery. This has also helped in improving quality of therapy. Injectable drug delivery has also proved beneficial in many cases such as unconsciousness, emergency conditions and nausea, due to ...
Press Release issued May 28, 2015: Injectable drug delivery is defined as administration of a drug or drugs directly into patients blood circulationthrough a delivery device. It is considered as the most common and effective route of administration of most therapeutic agents to achieve the desired quick response. The injectable route of drug administration is expected to continue to be an important delivery system. This has been attributed to reasons that injectable drug delivery system allows administration of drugs with poor oral bioavailability, delivery of the drug at the site of action, targeted drug delivery system. Reduction in the number of injection is achieved by various technologies such as controlled release, targeted delivery and needle free delivery thus overcoming the problems associated with conventional injectable drug delivery. This has also helped in improving quality of therapy. Injectable drug delivery has also proved beneficial in many cases such as unconsciousness, emergency
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The CPT Code 01991 is the code used for Anesthesia / other procedures. The general guidance for this code is that it is used for anesthesia for nerve block and injection procedure. Below you will find cost information associated with this procedure based upon the a set of publicly available data which details all doctors who billed Medicare for this code. These costs are a guideline of what you may be charged for this particular CPT code, but of course your results may vary ...
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An emergency multi-medication pump injection system is designed for use in rapidly and automatically calculating and administering multiple medications in an emergency setting. The system includes a compact, portable housing comprising a plurality of medication ports, each port configured to receive a corresponding ampoule containing a corresponding medication. The system further includes at least one pump on or within the housing for dispensing a calculated dosage amount of one or more medications from the ampoules, at least one delivery tube for conveying the medication(s) from the system for delivery to the patient, and safety means for ensuring that each ampoule can only be installed in a port to which the particular ampoule corresponds. The pump injection system may include data inputs for inputting data relating to patient weight, medication concentration, medication dosage, and the like.
An emergency multi-medication pump injection system is designed for use in rapidly and automatically calculating and administering multiple medications in an emergency setting. The system includes a compact, portable housing comprising a plurality of medication ports, each port configured to receive a corresponding ampoule containing a corresponding medication. The system further includes at least one pump on or within the housing for dispensing a calculated dosage amount of one or more medications from the ampoules, at least one delivery tube for conveying the medication(s) from the system for delivery to the patient, and safety means for ensuring that each ampoule can only be installed in a port to which the particular ampoule corresponds. The pump injection system may include data inputs for inputting data relating to patient weight, medication concentration, medication dosage, and the like.
For super-precision cylindrical roller bearings with a bore diameter d , 80 mm, SKF recommends the oil injection method. With the oil injection method, oil under high pressure is injected via ducts and distribution grooves between the bearing and bearing seat to form an oil film (fig. 1). This oil film separates the mating surfaces and considerably reduces the friction between them and virtually eliminates the risk of damaging the bearing or the spindle shaft. This method is typically used when mounting or dismounting bearings directly on tapered shaft seats. Where bearings with a cylindrical bore are concerned, the oil injection method can only be used for dismounting ...
For super-precision cylindrical roller bearings with a bore diameter d , 80 mm, SKF recommends the oil injection method. With the oil injection method, oil under high pressure is injected via ducts and distribution grooves between the bearing and bearing seat to form an oil film (fig. 1). This oil film separates the mating surfaces and considerably reduces the friction between them and virtually eliminates the risk of damaging the bearing or the spindle shaft. This method is typically used when mounting or dismounting bearings directly on tapered shaft seats. Where bearings with a cylindrical bore are concerned, the oil injection method can only be used for dismounting ...
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An excavation system for forming a wellbore through a subterranean formation, the system employing pressurized drilling fluid with impactors mixed therein. The pressurized fluid with impactors is directed to a drill string having a drill bit with nozzles on its lower end. The fluid impactor mixture is discharged from the nozzles and against the formation, wherein the impactors contact, compress, and fracture the formation to excavate through the formation. The system includes an impactor injection system that injects impactors into a stream of pressurized drilling fluid to form the mixture. The injection system operates at substantially the same pressure as the pressurized drilling fluid.
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Building on the success of its launch last year SMi Group are proud to presents the 2nd Injectable Drug Delivery Conference and exhibition.. Conference Overview:. The global injectable drug delivery market is expected to grow from $400 billion to $1200 billion by 2046 with a CAGR of 12.8% according to Research Markets Reports. Therefore, the conference will aim to discuss the key developments in this field and the latest technological advancements.. Join us on the 15th - 16th May 2019, in London along with two pre-conference workshops taking place on 14th May 2019.. Key Speakers Include:. - Bjørg Kaae Hunter, Device Engineering Manager, GlaxoSmithKline. - Blake Green, Senior Manager Regulatory Affairs, Amgen. - Quentin Le Masne, Head of Engineering for Electro-Medical Drug Delivery Devices, Merck. - Vasco Filipe, Formulation and Drug Process Development Section Head for Biologics, Sanofi. - Stephen Paboojian, Senior New Technology Project Leader II, Novartis Pharma AG. - Terry Reed, Director of ...
Injection Drug Use and HIV Infection. From 2008-2011, injection drug use was responsible for approximately 10% of HIV cases. For more details, including analysis by.Inside the Chamber - Lethal injection is not a light topic, but its the subject of much debate. Find out about the various procedures.Find out how fuel-injection systems work and about the various configurations used in. and electronic fuel injection was used widely on European cars starting.. Learn more about the causes and symptoms of Overactive Bladder (OAB). Click here for full safety and product information, including boxed warning.Comentariastas. Posted julio 16th. preventing the name from being used for wines made. I like watching TV purchase voveran online The device availability in.2.5 mL of IMIZOL® per injection. Makes it cost effective and practical. Dosage For further information including dose rate and complete directions and warnings,.. Facet Joints Injections. Spinal injections are used for both treatment and ...
A dual head contrast media injection system performs a patency check or test injection, determining flow rate and/or flow volume from the programmed protocol. The tubing that connects syringes to a patient shares only a short common section near to the patient. Appropriate injection steps are taken to compensate for tubing elasticity. A wireless remote control and a touch screen control are provided, improving functionality and information delivery. The display brightness is controlled based on the ambient light, and the display panel includes a double swivel permitting re-orientation. The orientation of the display may also be controlled based on, e.g., the current step, the tilt angle of the powerhead, or a manual control. Furthermore, the display is customizable to identify the type of fluid (contrast, saline, etc.) on either side of the injector, to provide matched color coding, and to provide a folder/tab analogy for retrieving injection protocol parameters.
An injection system and method for blending an additive into a main fluid flow stream at a controlled ratio, characterized by a controller wherein the electrical circuitry thereof is contained in an explosion-proof housing having a window through which electromagnetic energy, such as an infrared command signal, can be transmitted. The circuitry contained within the explosion-proof housing includes a receiver for receiving the electromagnetic energy transmitted through the window and a processor or processors for decoding information included in the electromagnetic energy and for carrying out one or more functions based on such information. Also disclosed is an additive injection correction technique, a clean line technique and related and other features of the system and method.
The VC series, direct injection system, does not require carrier gas, it can be used with either a liquid or gas flow meter, allowing for easy...
meropenem for injection) and other antibacterial drugs, MERREM I.V. Meropenem injection is in a class of medications called antibiotics. Learn how to use Aspen Meropenem, and its dosage, warnings, side-effects, and more. (8.4) • Renal Impairment: Dose adjustment is necessary, if creatinine /min or less. Use of Meropenem must be discussed with the Infectious Diseases Team. For intravenous infusion meropenem vial may be directly constituted with 0.9% sodium chloride or 5% glucose (dextrose) solutions for infusion. Meropenem is not addictive. FDA REQUESTED LABELING CHANGES AS PER THE AGENCY REVIEW . This medicine will not work for colds, flu, or other virus infections. (meropenem for injection) FOR INTRAVENOUS USE ONLY To reduce the development of drug-resistant bacteria and maintain the effectiveness of MERREM® I.V. Counsel patients that antibacterial drugs including meropenem for injection should only be used to treat bacterial infections. Meropenem powder for injection (Demo SA, Noriderm ...
The application of therapeutic injections and regional anesthesia requires knowledge of equipment that includes needles, syringes, and catheters. The Luer lock is a conical tip that allows easy exchan... more
Cingal TM , Monovisc ® and Orthovisc ® may not be suitable for everyone. Talk to your doctor if you have questions regarding these products, or for more information on pain associated with osteoarthritis of the knee. Product information is only
Acunivive 90 Injection System official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology.
DUBLIN, Jan 30, 2017 /PRNewswire/ -- Global Automotive Fuel Injection Systems Market 2016-2022 - Analysis By Vehicle Type, Component Type, Fuel Type &...
in classic 350 available is fuel injection system - Read all answers for this question posted by Sameer Qureshi for Royal Enfield Classic 350
Snow Performance has combined performance, quality, and easy installation in this new water-methanol injection system engineered specifically for your 2015+ Subaru WRX (non STI). Increase your pump gas octane by 25 points and make more power effic...
Press release - Fact.MR - Automotive Fuel Injection System Market Expected To Grow at a Steady CAGR of 3% Through 2027 | Key Players are Denso Corporation, Delphi Technologies PLC, Continental AG, etc. - published on openPR.com
5 December 1997 Slurry injection system claims less disturbanceREDUCED surface damage and pasture disturbance are claimed by Chavtrac for its latest Veenhu
Compare prices from local garages for Honda Fuel Injection System in Darlington in seconds with Who Can Fix My Car. Get quotes & book a visit!
Liebherr develops and produces innovative injection systems. As an engine manufacturer with many years of experience, Liebherr is familiar with the
Liebherr develops and produces innovative injection systems. As an engine manufacturer with many years of experience, Liebherr is familiar with the
The TDS is a high-performance thermal desorption system that uses the GERSTEL cooled injection system to function as both a cryogenic trap and a GC inlet.
Shop Banks Power 45181 Double-Shot Water-Methanol Injection System for the 2008-2010 Ford 6.4L Powerstroke . XDP carries all the parts and accessories you need for the best diesel performance.
(KudoZ) English to Greek translation of re-establish dialogue with injection system: αποκαταστήστε την επικοινωνία με το σύστημα ψεκασμού καυσίμου [Διάγνωση- έλεγχος - Automotive / Cars & Trucks (Tech/Engineering)].
Shop for Fuel Injection Systems 2003 IMechE Conference Transactions 2003-2 from WHSmith. Thousands of products are available to collect from store or if your orders over £20 well deliver for free.
Occasionally, a specific muscle may generate pain due to sustained contraction and subsequent localized ischemia. These areas of muscle pain are called trigger points and can be treated with injection of small amounts of local anesthetic solution, along with specific physical therapy treatments.
The bladder and urethra are supported by muscles, ligaments, and connective tissues around the base of the bladder. This support prevents the leakage of urine, along with the watertight seal provided by the urethra. As a result of pregnancy, childbirth, and aging, or damage by scarring from surgery or radiotherapy, these structures may become damaged or weakened, thus causing stress incontinence, meaning an involuntary loss of urine that occurs during physical activity such as coughing, sneezing, laughing, or exercise . The injection of bulking agents such as collagen around the urethra aims to improve the lost support of the bladder and urethra. The substance most commonly used for injection is collagen; other bulking agents are being developed, for example, a silicon base suspended in a viscous gel called Macroplastique. Teflon paste, introduced in the 1970s, initially gave good results, but was discontinued after reported problems with excessive scarring and with the migration of Teflon ...
There are a number of coccyx injection procedures available to patients, and we will run through some common types below. The procedure will take place in theatre under full aseptic conditions with the patient on his or her stomach. The injection site is thoroughly cleansed and numbed with an anaesthetic before fluoroscopy (live X-ray) is used to guide the needle into the right area to avoid organ injury. A small needle in the back of your hand can be used to administer sedation or in case of an emergency.. Coccygeal injection consisting of direct administration of steroid and local anaesthetic.. Ganglion impar injection treats coccyx pain by blocking the pain signals to the brain, and these injections can be both diagnostic and therapeutic.. A caudal epidural injection for coccyx pain targets the nerves at the spines lower end and is administered in the epidural space. This space can be accessed through a hole which is found at the lower end of the sacrum.. A coccygeal nerve block is also used ...
Physician reviewed testosterone injection patient information - includes testosterone injection description, dosage and directions.
Dilute carbon dioxide injection and storage[edit]. Dilute carbon dioxide injection requires injection at depths where carbon ... "Carbon Sequestration via Direct Injection" (PDF). MIT.. *^ "Ocean Storage of CO2" (PDF). ieaghg.org. IEA Greenhouse Gas R&D ... a b c Brewer, Peter G. "Direct Injection of Carbon Dioxide into the Oceans." The Carbon Dioxide Dilemma: Promising Technlogoies ... Dilute ocean injection requires little infrastructure in comparison to other forms of ocean injection.[4] The IEA Greenhouse ...
Grid injection without compression[edit]. The core of the system is a proton exchange membrane (PEM) electrolyser. The ... and direct injection into the gas grid. The overall goal of the project is to assess those technologies and various usage paths ...
Methanol Injection[edit]. Methanol/water injection has been around since the 1920s but was not utilized until World War II. ... Water injection[edit]. Main article: Water injection (engines). An alternative to intercooling is injecting water into the ... "Get Schooled: Water Methanol Injection 101". Dragzine.. *^ a b c "How Turbocharged Piston Engines Work". TurboKart.com ... Recycling back into the turbocharger inlet is required on an engine that uses a mass-airflow fuel injection system, because ...
Beam-injection analysis of semiconductors[edit]. The nature of the SEM's probe, energetic electrons, makes it uniquely suited ... Cathodoluminescence and EBIC are referred to as "beam-injection" techniques, and are very powerful probes of the optoelectronic ... the SEM beam injection of carriers will cause electron beam induced current (EBIC) to flow. ...
Execution by lethal injection[edit]. Potassium chloride is commonly used in the practice of execution by lethal injection. ... For this reason, it is used in surgical abortion, and as the third and final drug delivered in the lethal injection process. ... It is also used in medicine, lethal injections, scientific applications, food processing, soaps, and as a sodium-free ... for executions by lethal injection. It occurs naturally as the mineral sylvite, and in combination with sodium chloride as ...
... the field strength is again decreased to injection level, starting a new injection cycle. Depending on the method of magnet ... Injection procedure[edit]. Unlike in a cyclotron, synchrotrons are unable to accelerate particles from zero kinetic energy; one ... Starting from an appropriate initial value determined by the injection energy, the field strength of the dipole magnets is then ...
Heated-manifold direct-injection[edit]. Heated-manifold direct-injection die casting, also known as direct-injection die ... The high-pressure injection leads to a quick fill of the die, which is required so the entire cavity fills before any part of ... or injection cylinder). This shot is then driven into the die by a hydraulic or mechanical piston. The biggest disadvantage of ... a vacuum pump removes air and gases from die cavity and metal delivery system before and during injection. Vacuum die casting ...
Trans-Mars injection[edit]. Trans-Mars injection diagram.. A = Hohmann transfer orbit. B = Conjunction mission. C = Opposition ... A trans-Mars injection (TMI) is a heliocentric orbit in which a propulsive maneuver is used to set a spacecraft on a trajectory ... Trans-Mars injections can be either a single maneuver burn, such as that used by the NASA MAVEN orbiter, or a series of perigee ... Transfer injections can place spacecraft into either a Hohmann transfer orbit or bi-elliptic transfer orbit. ...
Water and gas injection[edit]. Main article: Water injection (oil production). If the natural drives are insufficient, as they ... As with other drive mechanisms, water or gas injection can be used to maintain reservoir pressure. When a gas cap is coupled ... Secondary recovery involves the injection of gas or water to maintain reservoir pressure. The gas/oil ratio and the oil ...
Lethal injection[edit]. For more details on this topic, see Lethal injection. ... Washington is now the second state in the U.S. to use the single-dose sodium thiopental injections for death penalty executions ... This was the first execution in the state to use a single dose, single drug injection. His death was pronounced approximately ... Although death usually occurs within ten minutes of the beginning of the injection process, some have been known to take longer ...
Young blood injection[edit]. Further information: Young blood transfusion. Some clinics currently offer injection of blood ... Two clinics in California, run by Jesse Karmazin and David C. Wright,[99] offer $8,000 injections of plasma extracted from the ...
Supervised injection sites (SiS)[edit]. Main article: Supervised injection site. The provision of supervised injection sites, ... also referred to as safe injection sites, operates under the premise of harm reduction by providing the injection drug user ... avoiding the injection of drugs. *recognizing that one's own drug-taking behavior and attitudes in the presence of others will ... Insite was opened in 2003 and has dramatically reduced many harms associated with injection drug use. The research arm of the ...
Spray-injection repair[edit]. The FHWA manual[1] cites the spray-injection procedure as an efficient alternative to semi- ... Spray-injection device for pothole repair-all-in-one repair unit in Montreal, which allows the operator to work from the ... Spray-injection device for pothole repair-all-in-one repair unit in the Czech Republic ... Spray-injection device for pothole repair-truck and trailer unit in the United States ...
Tissue damage at injection sites[edit]. Severe injection site necrosis and sepsis has occurred (sometimes requiring amputation ... "TALWIN (pentazocine lactate) injection, solution". DailyMed. National Institute of Health. Retrieved 2011-12-10.. ... via injection,[6] and the reported incidence of its recreational use has declined precipitously since. ... of limb) with multiple injection of pentazocine lactate. In addition, animal studies have demonstrated that Pentazocine is ...
Injection[edit]. Injectable anaesthetics are used for the induction and maintenance of a state of unconsciousness. ... Drugs given to induce general anaesthesia can be either as gases or vapours (inhalational anaesthetics), or as injections ( ... Anaesthetists prefer to use intravenous injections, as they are faster, generally less painful and more reliable than ... In patients given a single injection of drug, this redistribution results in termination of general anesthesia. Therefore, ...
Intracytoplasmic sperm injection[edit]. ICSI technique is used in case of poor semen quality, low sperm count or failed ... In this case synthetic FSH by injection or Clomid (Clomiphene citrate) via a pill can be given to stimulate follicles to mature ... This technique involves an injection of a single healthy sperm directly injected into mature egg. The fertilized embryo is then ...
Epidural steroid injection[edit]. Main article: Epidural steroid injection. Epidural steroid injection may be used to treat ... Epidural techniques frequently involve injection of drugs through a catheter placed into the epidural space. The injection can ... "Epidural Steroid Injections". Pain Management Specialists.. *^ Norman D (2003). "Epidural analgesia using loss of resistance ... An epidural injection or infusion for pain relief (e.g. in childbirth) is less likely to cause loss of muscle power, but has to ...
... has been used since the 1970s in Australia as an emergency analgesic for short-term use, mostly by the Australian and New Zealand Defence Forces,[13] the Australian ambulance services,[10][35][36] and since 2018 by some Emergency medical services in Germany.[57] All of the currently used volatile anesthetic agents are organofluorine compounds. Aside from the synthesis of Freon (Thomas Midgley, Jr. and Charles F. Kettering, 1928)[58] and the discovery of Teflon (Roy J. Plunkett, 1938),[59] the field of organofluorine chemistry had not attracted a great deal of attention up to 1940 because of the extreme reactivity of elemental fluorine, which had to be produced in situ for use in chemical reactions. The development of organofluorine chemistry was a spin-off from the Manhattan Project, during which elemental fluorine was produced on an industrial scale for the first time. The need for fluorine arose from the need to separate the isotope 235U from 238U because the former, present in ...
"Cladribine- cladribine injection". DailyMed. 31 December 2019. Retrieved 4 March 2020.. *^ "FDA approves new oral treatment for ... "Leustat Injection. - Summary of Product Characteristics (SPC) - (eMC)". www.medicines.org.uk.. ... "PRODUCT INFORMATION LITAK© 2 mg/mL solution for injection" (PDF). TGA eBusiness Services. St Leonards, Australia: Orphan ... Terminal elimination half-life: Approximately 10 hours after both intravenous infusion and subcutaneous bolus injection[3]. ...
"Metal Injection. 2010-04-09. Retrieved 2011-10-28.. *^ "Friday Top: 25 Greatest Singing Drummers". Ultimate-guitar.com. ...
Scleral injection. *Conjunctivitis. Diagnosis[edit]. Differential diagnoses for the painful equine eye: *Ulceration ...
Only a limited number of emulsifiers are commonly regarded as safe to use for parenteral administration, of which the most important is lecithin.[medical citation needed] Lecithin can be biodegraded and metabolized, since it is an integral part of biological membranes, making it virtually non-toxic. Other emulsifiers can only be excreted via the kidneys,[citation needed] creating a toxic load. The emulsifier of choice for most fat emulsions used for parenteral nutrition is a highly purified egg lecithin,[36] due to its low toxicity and complete integration with cell membranes. Use of egg-derived emulsifiers is not recommended for people with an egg allergy due to the risk of reaction. In situations where there is no suitable emulsifying agent for a person at risk of developing essential fatty acid deficiency, cooking oils may be spread upon large portions of available skin for supplementation by transdermal absorption. Another type of fat emulsion Omegaven is being used experimentally within the ...
Fillers injections: collagen, fat, and other tissue filler injections, such as hyaluronic acid ...
Cosmetic filler injections. *Hair removal with laser or other modalities. *Hair transplantation - a cosmetic procedure ...
bilateral conjunctival injection. *injected or fissured lips, injected pharynx, or strawberry tongue ...
Initial injection station. Known also as "supply" or "inlet" station, is the beginning of the system, where the product is ... These instruments are installed along the pipeline on some specific locations, such as injection or delivery stations, pump ...
Anti-wrinkle Injections Diane Breast Reduction Jayla Butt Implant Kim Breast Implants ...
There is no cure for the condition.[2] Efforts may be used to try to speed hair regrowth such as cortisone injections.[1][2] ... Steroid injections are commonly used in sites where the areas of hair loss on the head are small or especially where eyebrow ... corticosteroid injections, or cream. The cream is not as effective and it takes longer in order to see results. ...
She was sentenced to death for six of the murders and was executed by lethal injection on October 9, 2002. ... Execution by lethal injection. Other names. Sandra Kretsch. Susan Lynn Blahovec. Lee Blahovec. Cammie Marsh Greene. Lori ...
"Vitamin B injections mentioned". Archived from the original on 2008-07-03. Retrieved 2008-07-29.. ... There are some reports of anaphylaxis caused by high-dose thiamin injections into the vein or muscle. However, the doses were ... may also be delivered by injection to reverse deficiencies.[13][unreliable medical source?] Both type 1 and type 2 diabetics ...
Insulin Injections. Insulin is a hormone that lowers the level of glucose (a type of sugar) in the blood by helping glucose ... Most people with diabetes take insulin injections based on their blood glucose levels, according to a plan that theyve worked ...
This weeks patent applications include an injection-patch inspired by jellyfish stings and software that generates celebrity ... Jellyfish injections. The stinging cells of jellyfish could soon be used to inject drugs and apply tattoos, according to two ... Read the jellyfish injections patent application.. Famous readings. Talking books are big business. Yet most famous actors are ... Because there is no toxin, the injection should be very quick and painless, and the threads would be extracted once the patch ...
Intravenous Injections. Br Med J 1962; 1 doi: https://doi.org/10.1136/bmj.1.5288.1342-a (Published 12 May 1962) Cite this as: ...
Painful Injections. Br Med J 1934; 1 doi: https://doi.org/10.1136/bmj.1.3815.309 (Published 17 February 1934) Cite this as: Br ...
"SetThreadContext DLL Injection". January 16, 2007. Retrieved September 1, 2008.. *^ Ben Botto (September 6, 2008). "DLL ... "Dll Injection". DreamInCode.net. MediaGroup1. May 4, 2006. Archived from the original on September 2, 2008. Retrieved August 31 ... In computer programming, DLL injection is a technique used for running code within the address space of another process by ... "Dll Injection using SetWindowsHookEx() Method". Game Reversal. April 3, 2008. Retrieved September 1, 2008.. ...
The injection site is located by dividing the buttock into four with a plus (+) shaped cross, and administering the injection ... This site is not recommended for repeated injections, due to its small area, it is difficult to rotate the injection site. To ... Intramuscular (also IM or im) injection is the injection of a substance directly into muscle. In medicine, it is one of several ... Subcutaneous injection Intravenous injection Taylor, C. R., Lillis, C., LeMone, P., Lynn, P. (2011) Fundamentals of nursing: ...
Safe injection practices are aimed at maintaining basic levels of patient safety and provider protections. ... Safe injection practices are part of Standard Precautions and are aimed at maintaining basic levels of patient safety and ... Unsafe injection practices put patients and healthcare providers at risk of infectious and non-infectious adverse events and ... As defined by the World Health Organization, a safe injection does not harm the recipient, does not expose the provider to any ...
Learn about different types of injections for back pain relief. ... sometimes doctors use injections or implanted devices to ... These injections include:. • Epidural steroid injections. When inflammation within the spinal column causes nerve-root ... Trigger point injections. These injections involve injecting a small amount of local anesthetic, sometimes along with a steroid ... Injections and Implants for Back Pain Relief. Procedures and devices that deliver pain medications locally, not orally. * ...
Borrowed from Middle French injection, from Latin iniectio. The mathematical sense is from French injection, introduced by ... The troubled business received a much-needed cash injection.. *(mathematics) A relation on sets (X,Y) that associates each ... "injection" in Trésor de la langue française informatisé (The Digitized Treasury of the French Language). ... A specimen prepared by injection.. *(category theory) A morphism from either one of the two components of a coproduct to that ...
CDC has hosted a number of meetings to engage partners interested in injection safety. Meeting summaries are available in the ... Injection Safety: Insurance Stakeholders Meeting - December 15, 2011. *Public Health Collaboration Models for Infection ... Safety by Design: Innovative Approaches for Safe Injections - May 2010. *Sticking with Safety: Eliminating Bloodborne Pathogen ... FAQs regarding Safe Practices for Medical Injections - Backgroundplus icon *General Questions ...
a Manufacture, Developer and Supplier of MIM/PIM Feedstock for the Metal Injection Molding Industry. We are located in Temecula ... Metal Injection Molding , Ceramic Injection Molding , MIM CIM - Duration: 6:20. dytmim 14,609 views ... Injection Molding with 3D Printing - How Its Used - Duration: 2:41. TriMech 225,977 views ... Metal Injection Molding Tips- ASH MIM - Duration: 5:18. Design2PartTradeShow 10,166 views ...
... The Financial Markets Freak Out When The Fed Hints That It May Slow Down The Injections. June 19, 2013. by Michael ... Injections, Interest Rates, Interest Rates Rise, Michael T. Snyder, Money Printing, Printing Money, Quantitative Easing, The ... program is that the stock market is now addicted to this constant injection of free money. The aptness of this analogy has ... what are they going to do when the Fed actually starts cutting back the monetary injections? ...
Botox injections can be used to temporarily reduce wrinkles but can also treat other health problems such as severe sweating or ... Can Botox Injections Relieve Arthritis Pain? (Mayo Foundation for Medical Education and Research) Also in Spanish ... Botulinum Toxin Injections: A Treatment for Muscle Spasms (American Academy of Family Physicians) Also in Spanish ... Injections in the face may also cause temporary drooping eyelids. You should not use Botox if you are pregnant or breastfeeding ...
Lidocaine injections into part of the trigeminal nerve near the brain under fluoroscopic guidance improved migraine and cluster ... Injection of local anesthetic into part of the trigeminal nerve under fluoroscopic guidance is being used to treat migraine and ... Lidocaine is used to treat headache in other ways: for example, in nasal sprays and drops and injections into muscles. But the ... Theoretically, patients with headache could get the injection repeatedly. Its also not a difficult procedure to learn. "The ...
Learn about topics such as How to Give a B12 Injection, How to Reduce Pain After an Injection, How to Read Syringes, and more ... Learn everything you want about Injections with the wikiHow Injections Category. ... Injections. Learn everything you want about Injections with the wikiHow Injections Category. Learn about topics such as How to ... Give a B12 Injection, How to Reduce Pain After an Injection, How to Read Syringes, and more with our helpful step-by-step ...
... an injection of hyaluronic acid could help ease your pain and stiffness. people with arthritis get these shots to help ... What are hyaluronic acid joint injections?. ANSWER If you have osteoarthritis that affects your knees, an injection of ... American Academy of Family Physicians Family Doctor: "Osteoarthritis of the Knee: Hyaluronic Acid Injections." ... American Academy of Family Physicians Family Doctor: "Osteoarthritis of the Knee: Hyaluronic Acid Injections." ...
I am getting botox injections to the bladder lining. Has anyone here had this and did it work?... ... I am getting botox injections to the bladder lining. Has anyone here had this and did it work? Also did you have frozen bladder ...
URL Injections are used by phishing attackers in online messages and applications in order to redirect users to their ... URL Injections are used by phishing attackers in applications, emails, instant messages, chat messages, etc. in order to ...
... the Supreme Court will decide if a drug protocol used in lethal injections violates the Constitutions prohibition on cruel and ... Supreme Court will review use of lethal injections. Richard Wolf, USA TODAY Published 4:25 p.m. ET Jan. 23, 2015 , Updated 8:42 ... Supreme Court will review use of lethal injections. In a case that could affect hundreds of death row inmates, the Supreme ... Supreme Court will review use of lethal injections In a case that could affect hundreds of death row inmates, the Supreme Court ...
Warnock has begun using PRP injections as a treatment to help alleviate knee pain associated with early arthritis. ... All injections are performed by Dr. Warnock, and he is assisted by his own supportive staff. In addition to PRP injections, ... PRP injections can help those who suffer from knee pain improve their quality of life and help those who are active feel less ... PRP injections can help those who suffer from knee pain improve their quality of life and help those who are active feel less ...
Ltd is an injection molders in China, offer the best quality China injection molding… ... We are manufacturer and supplier of Injection mould and Injection Molding . We export custom injection molding and mold. We ... Custom injection molding * 1. Custom Plastic Molds www.imoldmaking.com * 2. Custom injection molding At present, China plastic ... GC precision mould Co., Ltd is an injection molders in China, offer the best quality China injection molding & molds, go to our ...
Can the hypertonic solution J7131 and other supplies that we use be billed seperately or is this bundled with 36470 and 36471 CPT codes?
I start my injections on Saturday. Although I dont really have a phobia of needeles I do have a healthy fear of pain! How is ... My husband gave my IM injections in my hip, I gave myself the smaller injections in my stomach. I find out Thursday if I am ... I start my injections on Saturday. Although I dont really have a phobia of needeles I do have a healthy fear of pain! How is ... I took my first injections today of Lupron and it was a snap! It really did NOT hurt at ALL!! Now well see if theres going to ...
Im in need of cpt codes for Platelet Rich plasma Injections (PRP). The physicians have informed me that PRP is a concentrated ... PRP injections 0232T - Injection(s), platelet rich plasma, any site, including image guidance, harvesting and preparation when ... Platelet Rich Plasma Injections Since this has been an ongoing issue and there has been many comments regarding what codes, I ... PRP Injections. CPT Assistant recommends coding 86999 Unlisted transfusion medicine procedure when blood is withdrawn during a ...
An under-the-skin microchip device releasing drugs could someday be a substitute for daily injections, U.S. researchers who ... "Patient compliance is a big issue, especially when we are asking patients to give themselves daily injections of a drug," MIT ... 17 (UPI) -- An under-the-skin microchip device releasing drugs could someday be a substitute for daily injections, U.S. ... "These data validate the microchip approach to multiyear drug delivery without the need for frequent injections, which can ...
Cabotegravir and Rilpivirine Injections: learn about side effects, dosage, special precautions, and more on MedlinePlus ... Rilpivirine extended-release injection may cause serious adverse reactions soon after receiving the injection. A doctor or ... You will receive cabotegravir and rilpivirine injections once every month given as an injection of each medication into your ... Cabotegravir and rilpivirine injections may cause side effects. Tell your doctor if any of these symptoms are severe or do not ...
... that releases medication on command from an external wireless control could one day free patients from daily injections and ... Drug-Delivery Microchip Could Replace Daily Injections. In a Small Study, Patients Preferred Microchip Over Daily Injections, ... "Patient compliance is a big issue, especially when we are asking patients to give themselves daily injections of a drug," he ... the technology could be used to treat a wide range of conditions that require frequent or daily injections, says Robert Farra, ...
The expense of each intravitreal injection is higher than the reimbursement rate, and retina specialists worry that one of the ... Physicians often think of the injection as a 2-minute process of greeting the patient, giving the injection, and washing the ... Each injection we do costs $127.74 - $1.60 for materials, $97.88 for labor, and $28.26 for overhead - said Christina Weng, MD, ... But what she found, when she timed each step of the procedure in her practice for 14 patients who came in for an injection-only ...
Subacromial corticosteroid injection for rotator cuff disease and intra-articular injection for adhesive capsulitis may be ... Comparison 3 ANATOMICAL STEROID INJECTION (SITE DETERMINED BY CLINICAL FEATURES) VS TRIGGER POINT STEROID INJECTION, Outcome 1 ... Corticosteroid injections for shoulder pain.. Buchbinder R1, Green S, Youd JM. ... This review of corticosteroid injections for shoulder pain is one in a series of reviews of varying interventions for shoulder ...
JNeurosci Online ISSN: 1529-2401. The ideas and opinions expressed in JNeurosci do not necessarily reflect those of SfN or the JNeurosci Editorial Board. Publication of an advertisement or other product mention in JNeurosci should not be construed as an endorsement of the manufacturers claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in JNeurosci.. ...
  • Epidural Steroid Injection is a technique for relieving pain from spinal stenosis and spinal disc herniation . (google.com)
  • Randomised and pseudo-randomised trials in all languages of corticosteroid injections compared to placebo or another intervention, or of varying types and dosages of steroid injection in adults with shoulder pain. (nih.gov)
  • For rotator cuff disease, subacromial steroid injection was demonstrated to have a small benefit over placebo in some trials however no benefit of subacromial steroid injection over NSAID was demonstrated based upon the pooled results of three trials. (nih.gov)
  • For adhesive capsulitis, two trials suggested a possible early benefit of intra-articular steroid injection over placebo but there was insufficient data for pooling of any of the trials. (nih.gov)
  • Studies show that an effective first-response to an epidural steroid injection may be considered as an opportunity to administer more injections when the symptoms return. (spine-health.com)
  • An epidural steroid injection may help alleviate radicular pain felt in either your arm or leg resulting from pressure and irritation on one of the nerves. (emoryhealthcare.org)
  • What happens during the epidural steroid injection procedure? (emoryhealthcare.org)
  • What should I expect after an epidural steroid injection? (emoryhealthcare.org)
  • In the simplest of terms, an epidural corticosteroid (steroid) injection is a way to deliver pain medicine quickly into the body with a syringe. (hopkinsmedicine.org)
  • Why might I need an epidural steroid injection? (hopkinsmedicine.org)
  • If you have intense, difficult-to-treat pain in your legs or arms from inflamed spinal nerves, then an epidural steroid injection might give you quick relief. (hopkinsmedicine.org)
  • What are the risks of an epidural steroid injection? (hopkinsmedicine.org)
  • An epidural steroid injection generally causes no problems. (hopkinsmedicine.org)
  • How do I get ready for an epidural steroid injection? (hopkinsmedicine.org)
  • An epidural steroid injection is generally an outpatient procedure. (hopkinsmedicine.org)
  • An epidural steroid injection is another category. (spineuniverse.com)
  • For example, in an otherwise healthy individual, tendinitis may be adequately treated with only a local steroid injection. (clevelandclinic.org)
  • Agreeing that lethal injection may cause excessive pain, a federal judge told state corrections officials Tuesday to change the way they administer the fatal dose, or face a delay in death row inmate Michael Morales' Feb. 21 execution. (latimes.com)
  • This is the first time a federal judge has concluded that there is substantial evidence that people may be suffering pain during the lethal injection process. (latimes.com)
  • If state officials reject Fogel's options, the court will stay the execution and hold an evidentiary hearing in early May on Morales' assertions that execution by lethal injection is unconstitutional. (latimes.com)
  • But pointing in part to problems encountered during the recent executions of Stanley Tookie Williams and Clarence Ray Allen, Fogel also said Morales had raised legitimate fears that unexpected problems during the lethal injection process could cause extreme pain. (latimes.com)
  • In a case that could affect hundreds of death row inmates, the Supreme Court will decide if a drug protocol used in lethal injections violates the Constitution's prohibition on cruel and unusual punishment. (usatoday.com)
  • WASHINGTON -- In a case that could have broad implications for hundreds of death row inmates, the Supreme Court will consider whether a drug protocol used in recent lethal injections violates the Constitution's prohibition on cruel and unusual punishment. (usatoday.com)
  • BEIJING (Reuters) - China's capital plans to use lethal injections in executions by the end of the year and firing squads will eventually be phased out across the country, state media on said on Tuesday, quoting law officials. (reuters.com)
  • Lethal injections were "cleaner, safer and more convenient," the official China Daily quoted the director of China's Supreme People's Court, Hu Yunteng, as saying. (reuters.com)
  • Lethal injection was legalised in China in 1997, and was first used in southwestern Yunnan region the next year, the China Daily said. (reuters.com)
  • In the United States, there was a de facto moratorium on the death penalty late in 2007 and early in 2008 as the Supreme Court considered whether lethal injection was cruel and unusual punishment. (reuters.com)
  • The Illinois-based pharmaceutical company Hospira, which manufactures midazolam, says it opposes the use of its products in lethal injections and no longer sells it to prison hospitals. (cnn.com)
  • Virginia is adding a drug used in a controversial Ohio execution to its roster of chemicals for lethal injections over the objections of the drug's manufacturer. (cnn.com)
  • The state Department of Corrections announced Thursday that it would have the sedative midazolam available as an alternate drug for lethal injections. (cnn.com)
  • THE first Briton to be executed in the United States for seven years was put to death by lethal injection early today after the Georgia Pardons and Paroles Board rejected a petition of protest from the European Union and a personal appeal from Tony Blair. (telegraph.co.uk)
  • But the next time they do, they are planning to use a cocktail for lethal injection that has never been tried before, including an anesthetic that hasn't been used in executions anywhere. (msnbc.com)
  • Executives at the company that makes Brevital, Par Pharmaceutical, were surprised to find that Indiana had gotten a hold of their drug for use in lethal injections. (msnbc.com)
  • Indiana follows a three-drug combination for lethal injection which begins with Brevital, the anesthetic, followed by a paralytic agent, pancuronium bromide, and then potassium chloride which stops the heart. (msnbc.com)
  • SAN FRANCISCO - California has dropped its legal efforts to win approval of a three-drug method of lethal injection and will instead propose single-drug executions, a prisons spokesman said Wednesday. (latimes.com)
  • State corrections officials Tuesday proposed new lethal injection procedures, a first step toward resuming executions in California after a four-year halt. (latimes.com)
  • But the revisions appear to address the concerns of a federal judge who deemed the previous lethal injection practices unconstitutional for their risk of inflicting cruel and unusual punishment. (latimes.com)
  • Corrections officials heard overwhelming condemnation of proposed new lethal injection procedures Tuesday at the first-ever public hearing on execution methods in the state. (latimes.com)
  • State officials launched a two-month forum Friday for public comment on revised lethal injection procedures in a step toward resuming executions as early as next year. (latimes.com)
  • Attorneys for the state of California and death row prisoners have agreed to a timetable for reviewing new lethal injection procedures, effectively postponing any such executions for another year. (latimes.com)
  • A flurry of litigation challenging the constitutionality of lethal injection has placed a spotlight on growing evidence that condemned inmates may not be properly anesthetized and therefore experience excruciating pain during executions. (latimes.com)
  • NEW YORK (Reuters) - - Pfizer Inc has taken steps to ensure that none of its products are used in lethal injections, the largest U.S. drugmaker said on Friday. (reuters.com)
  • We are enforcing a distribution restriction for specific products that have been part of, or considered by some states for, their lethal injection protocols," the New York-based drugmaker said on its website. (reuters.com)
  • Pfizer strongly objects to the use of its products as lethal injections for capital punishment. (reuters.com)
  • Pfizer's distribution restriction limits the sale of the seven products to a select group of wholesalers, distributors, and direct purchasers under the condition that they will not resell these products to correctional institutions for use in lethal injections, the company said. (reuters.com)
  • Gold injections may decrease the inflammation of rheumatoid arthritis. (medicalnewstoday.com)
  • These injections are not pain relievers, but they decrease pain because they decrease inflammation. (medicalnewstoday.com)
  • Brad Lidge has received a cortisone injection for an inflammation in his right elbow. (philly.com)
  • Epidural steroid injections may help control inflammation and pain arising from one or more spinal motion segments. (spine-health.com)
  • If pain resolves or decreases after injection, then the pain is likely to be attributable to inflammation of either the subacromial bursa or the rotator cuff. (medscape.com)
  • Even though the success rate of epidural steroids varies among different studies, I generally agree with the author that cortisone injections can be helpful to treat pain and inflammation in many patients with spinal disorders. (spineuniverse.com)
  • In general, cortisone injections serve to decrease pain and inflammation temporarily so that the patient can resume the rehabilitation more effectively. (spineuniverse.com)
  • Steroid injections often reduce joint inflammation, helping preserve joint structure and function. (clevelandclinic.org)
  • Overview of botulinum toxin for cosmetic injections. (mayoclinic.org)
  • A study by Lee et al tested botulinum toxin type B for subacromial injections and concluded that injections with this agent may be an alternative to steroid injections. (medscape.com)
  • The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms including: loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, and trouble swallowing. (botoxcosmetic.com)
  • Botox injections work by weakening or paralyzing certain muscles or by blocking certain nerves. (medlineplus.gov)
  • Can Botox Injections Relieve Arthritis Pain? (medlineplus.gov)
  • Finally, this Thursday, I am getting botox injections to the bladder lining. (medhelp.org)
  • In the new study, researchers recruited 60 obese patients in a trial to compare the effects of gastric botox injections against a placebo. (livescience.com)
  • After 24 weeks, those who were given the Botox injections showed no edge in weight loss. (livescience.com)
  • On the basis of our findings, I would not recommend gastric Botox injections to people who want to lose weight," researcher Mark Topazian, a professor at the Mayo Clinic, in Rochester, Minn., said in a statement. (livescience.com)
  • What are hyaluronic acid joint injections? (webmd.com)
  • When should I consider trying hyaluronic acid joint injections? (webmd.com)
  • Articular or joint injections are preceded by an aspiration withdrawing joint fluid or blood. (spineuniverse.com)
  • Sacroiliac (SI) joint injections may be used to diagnose and treat pain stemming from the SI joint and/or the posterior pelvis. (spine-health.com)
  • Sacroiliac joint injections treat pain originating from the SI joint, which connects the spine to the pelvis. (spine-health.com)
  • SI joint injections may be given when there is a positive pain response to an SI joint provocative test (moving the SI joint in various directions to check the source of pain) and when SI joint pain is suspected clinically. (spine-health.com)
  • SI joint injections are usually not given if a patient is pregnant or has an infection, blood disorder, certain types of diabetes mellitus, or cancer. (spine-health.com)
  • Risks related to SI joint injections usually occur infrequently. (spine-health.com)
  • 1. Nacey NC, Patrie JT, Fox MG. Fluoroscopically Guided Sacroiliac Joint Injections: Comparison of the Effects of Intraarticular and Periarticular Injections on Immediate and Short-Term Pain Relief. (spine-health.com)
  • During the first week daily injections of 33.3 micrograms of growth hormone per kg of bodyweight were given. (amazonaws.com)
  • WASHINGTON, Feb. 17 (UPI) -- An under-the-skin microchip device releasing drugs could someday be a substitute for daily injections, U.S. researchers who tested a device on eight women said. (upi.com)
  • Patient compliance is a big issue, especially when we are asking patients to give themselves daily injections of a drug," MIT engineering Professor Dr. Michael J. Cima, one of the idea's developers, told health information services Web site WebMD. (upi.com)
  • Feb. 16, 2012 -- An experimental, implanted drug-delivery microchip that releases medication on command from an external wireless control could one day free patients from daily injections and improve treatment compliance. (webmd.com)
  • If future research is promising, the technology could be used to treat a wide range of conditions that require frequent or daily injections, says Robert Farra, the study's author and chief operating officer of the company developing the drug-delivery device, MicroCHIPS Inc. (webmd.com)
  • The study, conducted by MicroCHIPS and MIT researchers, originally included eight women in Denmark with severe osteoporosis who had been taking daily injections of the bone-building drug Forteo . (webmd.com)
  • An analysis of the remaining seven patients confirmed that the microchip delivered the osteoporosis drug in comparable doses to daily injections with no unwanted side effects. (webmd.com)
  • The women reported that they could not feel the devices and expressed a preference for the implanted microchip over daily injections for future treatment. (webmd.com)
  • Patient compliance is a big issue, especially when we are asking patients to give themselves daily injections of a drug," he tells WebMD. (webmd.com)
  • OU Health Services administers allergy injections to patients who are currently under the care of a board-certified allergist. (ou.edu)
  • Patients are required to wait 30 minutes after receiving allergy injections. (ou.edu)
  • Health Services provides allergy injections only on Mondays and Thursdays, between 8am-4pm (9am-3pm during the summer), and requires a 30 minute wait-time following all allergy injections. (umn.edu)
  • Before allergy injections are given an appointment must be made with a Physician or Nurse Practitioner to ensure instructions from allergist are clear. (baylor.edu)
  • Students must remain in the lobby for 20-30 minutes after receiving an allergy injection, failure to comply may result in the health center no longer giving allergy injections to the student. (baylor.edu)
  • Epidural steroid injections may be given in the cervical, thoracic, lumbar or sacral regions of the spine. (spine-health.com)
  • Caudal injection -the needle is placed into the sacral area below the lumbar spine through an opening called the sacral hiatus. (spine-health.com)
  • In the lumbar spine, 53% to 56% of patients reported significant improvement in pain and functional outcome up to 1 year (a total of 3 to 4 injections were given during this period). (spine-health.com)
  • Rarely, the spinal sac, which contains the nerves, may be penetrated during a lumbar injection. (emoryhealthcare.org)
  • Lumbar epidural injections are a relatively simple technique. (spineuniverse.com)
  • The Pain Management Center (PMC) wants to try facet injections on me, cervical and lumbar. (healingwell.com)
  • As defined by the World Health Organization, a safe injection does not harm the recipient, does not expose the provider to any avoidable risks and does not result in waste that is dangerous for the community. (cdc.gov)
  • Although rare, some serious risks associated with epidural steroid injections include infection, nerve damage, bleeding, dural puncture (cerebrospinal fluid leak), and/or damage to the spinal cord. (spine-health.com)
  • What are the risks associated with epidural steroid injections? (emoryhealthcare.org)
  • Your doctor will also make sure you understand the potential benefits and risks of steroid injections. (clevelandclinic.org)
  • The dorsogluteal (buttock) site is not recommended for use in any patient population due to its location near major blood vessels and nerves, as well as having inconsistent depth of adipose tissue, with very few injections in this area injected to the correct depth to administer as a true intramuscular injection. (wikipedia.org)
  • This is the only intramuscular injection site for which research recommends aspiration (drawing back) of the syringe prior to injection, due to higher likelihood of accidental intravenous administration in this area. (wikipedia.org)
  • It is given by intramuscular injection one to two times per month. (healthcentral.com)
  • One trial suggested short-term benefit of intra-articular corticosteroid injection over physiotherapy in the short-term (success at seven weeks RR=1.66 (1.21, 2.28). (nih.gov)
  • Subacromial corticosteroid injection for rotator cuff disease and intra-articular injection for adhesive capsulitis may be beneficial although their effect may be small and not well-maintained. (nih.gov)
  • [ 2 ] If this is not effective, some patients may benefit from a subacromial corticosteroid injection. (medscape.com)
  • In a study by Shams et al that included 40 patients with symptomatic partial rotator cuff tears, PRP injection yielded better early results than corticosteroid injection, though after 6 months, there was no longer a statistically significant improvement. (medscape.com)
  • What is an epidural corticosteroid injection? (hopkinsmedicine.org)
  • What happens after an epidural corticosteroid injection procedure? (hopkinsmedicine.org)
  • Answer: No. To obtain the cells for injection, code 86999, Unlisted transfusion medicine procedure, should be reported when for example, intraoperatively, 60 ccscc's of blood are drawn from the patient, centrifuged for 15 minutes to separate the platelet-rich plasma (fibrin) from the platelet-poor plasma and red cells, and injected into the operative site. (aapc.com)
  • The placement/injection of the cells into the operative site is an inclusive component of the operative procedure performed and not separately reported, and would be considered an inclusive component of the operative procedure performed. (aapc.com)
  • Weng said she decided to do the observational activity-based cost analysis because the Common Procedural Terminology (CPT) code for intravitreal injection (67028) is closely scrutinized by regulators who are checking to make sure that physicians are not being overpaid for the very common procedure. (medscape.com)
  • But what she found, when she timed each step of the procedure in her practice for 14 patients who came in for an injection-only appointment and added in the associated costs, was that they are actually being underpaid. (medscape.com)
  • A urethral bulking injection is a gynecological procedure and medical treatment used to treat involuntary leakage of urine: urinary incontinence in women. (wikipedia.org)
  • These injections involve injecting a small amount of local anesthetic, sometimes along with a steroid medication, directly into painful trigger points, specific sites on the muscles that cause pain (both locally and throughout the back) when your doctor presses on one during an exam. (arthritis.org)
  • Injection of local anesthetic into part of the trigeminal nerve under fluoroscopic guidance is being used to treat migraine and other headaches. (medscape.com)
  • Prior to the injection, the skin over the treatment site is cleaned and numbed by injecting a local anesthetic. (spine-health.com)
  • Gold injections: Can they treat rheumatoid arthritis? (medicalnewstoday.com)
  • However, in a patient with rheumatoid arthritis, injections are generally a small part of a multi-faceted treatment approach. (clevelandclinic.org)
  • The same search now only returns about 175K sites and many of those are discussing the injection. (sans.edu)
  • An SI joint injection may be given around the joint-periarticular injection or within the joint-intra-articular injection. (spine-health.com)
  • Sometimes, both intra-articular and periarticular injections may be given together to increase injection efficacy. (spine-health.com)
  • Some studies suggest that the peri-articular injections may be more effective in providing pain relief compared to intra-articular injections. (spine-health.com)
  • CINCINNATI , June 3, 2019 /PRNewswire/ -- Enable Injections, Inc. , a company developing and manufacturing advanced wearable infusion devices for combination products, today announced it has entered into a multi-product development agreement with Sanofi S.A . The enFuse ™ , developed and manufactured by Enable Injections, enables patient-administered subcutaneous delivery of high-volume therapeutics outside of a healthcare facility. (prnewswire.com)
  • The findings, presented here at the American Society of Retina Specialists 2019 Annual Meeting, are particularly significant, Weng said, because a mid- to high-volume practice can do 20 to 50 injections each day. (medscape.com)
  • Muscles have larger and more blood vessels than subcutaneous tissue and injections here usually have faster rates of absorption than subcutaneous injections or intradermal injections. (wikipedia.org)
  • Cincinnati -based Enable Injections is an investigational-stage company developing and manufacturing on-body subcutaneous infusion delivery systems designed to help improve patient quality of life. (prnewswire.com)
  • Common injection types are intravenous (into a vein), subcutaneous (under the skin), and intramuscular (into muscle). (britannica.com)
  • Special judicial police would be trained to deliver the prisoners and administer the injections, while medical staff would supervise the drugs and confirm the deaths, the report added. (reuters.com)
  • While UMD Health Services does not conduct allergy testing, we will store, without liability, a student's current vial of allergy serum and administer the injections. (umn.edu)
  • Unsafe injection practices put patients and healthcare providers at risk of infectious and non-infectious adverse events and have been associated with a wide variety of procedures and settings. (cdc.gov)
  • The study also found that after the injection, 88% of patients required less medication for ongoing pain relief. (medscape.com)
  • Theoretically, patients with headache could get the injection repeatedly. (medscape.com)
  • patients should know PRP injections are approved by the FDA. (prweb.com)
  • Epidural Steroid Injections help patients with disc herniations , disc bulges, degenerative disc disease, spinal stenosis and sciatica . (google.com)
  • Patients using this treatment "are freed from the daily reminder, or burden, of disease by eliminating the need for regular injections," MicroChips co-founder and Massachusetts Institute of Technology chemical engineer and surgery Professor Robert Langer said. (upi.com)
  • This is especially concerning, considering that intravitreal injection is our most common and best tool for helping patients with retinal disease," he added. (medscape.com)
  • In the cervical spine, 54% to 80% of patients reported significant improvement in pain and functional outcome from 6 months to 2 years (with a total of 3 to 6 injections given during this period). (spine-health.com)
  • The extended-release version can also cause nodules (little bumps) at the site of injection, although patients report that they fade with time. (healthcentral.com)
  • In a study of 40 patients with shoulder impingement syndrome with findings of rotator cuff tendinitis or subacromial bursitis on magnetic resonance imaging (MRI), three 20-mg injections of the nonsteroidal anti-inflammatory drug (NSAID) tenoxicam at weekly intervals yielded results comparable to those of a single 40-mg injection of methylprednisolone acetate. (medscape.com)
  • However, a study comparing single-dose subacromial injections of betamethasone (7 mg) and lornoxicam (8 mg) in 70 patients with subacromial impingement syndrome found that whereas the patients in the NSAID group achieved rapid functional recovery that partially extended into the intermediate term, the results were inferior to those seen in the steroid group. (medscape.com)
  • Levocarnitine injections such as Cardispan are indicated for patients with secondary carnitine deficiency due to inborn errors of metabolism and for patients who develop a carnitine deficiency from undergoing hemodialysis for end stage renal disease, states DailyMed. (reference.com)
  • Patients with metabolic disorders are typically given an intravenous injection of 50 milligrams per kilogram. (reference.com)
  • Patients receiving hemodialysis usually receive 10 to 20 milligrams per kilogram intravenously as an injection or infusion after each session. (reference.com)
  • For these patients, injections are only given with great caution. (clevelandclinic.org)
  • [ 4 ] In general, subacromial injection with corticosteroids should not be performed more than four times per year. (medscape.com)
  • [ 8 ] The authors suggested that a single lornoxicam injection may be an alternative only in cases where corticosteroids are contraindicated. (medscape.com)
  • Like most joint and soft-tissue injections with corticosteroids or anesthetics, subacromial injections can be either diagnostic or therapeutic. (medscape.com)
  • Cervical (neck) epidural injections are a very specialized technique done in our office only by skilled and experienced anesthesiologists. (spineuniverse.com)
  • Tell your doctor or nurse immediately if you experience any of the following symptoms during or shortly after your injection: difficulty breathing, stomach cramps, sweating, mouth numbness, anxiety, flushing, lightheadedness, or dizziness. (medlineplus.gov)
  • If RA symptoms return or worsen, then an individual will go back to having the injections weekly. (medicalnewstoday.com)
  • Brashear and colleagues had previously reported (New England Journal of Medicine, August 2002) that one-time injections of BoNTA are safe and effective in people with wrist and finger spasticity after a stroke. (medicalnewstoday.com)
  • Platelet-rich plasma injections can be administered intramuscularly. (wikipedia.org)
  • I'm in need of cpt codes for Platelet Rich plasma Injections (PRP). (aapc.com)
  • Injection of platelet-rich plasma (PRP) has also been employed for rotator cuff disease. (medscape.com)
  • Most people with diabetes take insulin injections based on their blood glucose levels, according to a plan that they've worked out with their doctor. (kidshealth.org)
  • One thing that always makes me wince is a news story about some new oral diabetes drug that the reporter says promises to free people with diabetes from "painful insulin injections. (healthcentral.com)
  • The same is true of most insulin injections. (healthcentral.com)
  • Many students need regular injections for allergies. (umn.edu)
  • In addition to PRP injections, arthritis pain relief treatments may include viscosupplementation, nonsteroidal anti-inflammatory pain medications, bracing, and physical therapy. (prweb.com)
  • Previous research has shown gold injections to be just as effective as methotrexate, according to a historical report of RA treatments in the medical journal, JSM Arthritis . (medicalnewstoday.com)
  • While many treatments, including corticosteroid injections in and around the shoulder, are advocated to be of benefit for shoulder pain, few are of proven efficacy. (nih.gov)
  • The injections may also help to improve the functional outcome of the SI joint through participation in rehabilitative treatments such as physical therapy and other therapies. (spine-health.com)
  • You will receive cabotegravir and rilpivirine injections once every month given as an injection of each medication into your buttocks. (medlineplus.gov)
  • Gold injections are usually injected into the buttocks. (medicalnewstoday.com)
  • An epidural injection can be given in the neck, mid-back or lower back/buttocks. (spine-health.com)
  • The Dallas County Medical Examiner's office said they found a silicone-type substance and fresh injection marks on Reid's buttocks. (usatoday.com)
  • i know in pediatrics, its used for kids getting frequent injections so it doesnt hurt. (dailystrength.org)
  • These data validate the microchip approach to multiyear drug delivery without the need for frequent injections, which can improve the management of many chronic diseases like osteoporosis, where adherence to therapy is a significant problem," said study author Robert Farra, president of MicroChips Inc., which developed the device. (upi.com)
  • Frequent steroid injections, more often than once every three or four months, are not recommended because of the increased risk of weakening tissues in the treated area. (clevelandclinic.org)
  • Despite the goal of healthcare in many countries to follow evidence based practices, this site is commonly preferred by healthcare professionals against research recommendation, often due to a lack of knowledge surrounding alternative sites for injection. (wikipedia.org)
  • Safe injection practices are part of Standard Precautions and are aimed at maintaining basic levels of patient safety and provider protections. (cdc.gov)
  • Woman who received more than 16 injections warns against illegal practices. (go.com)
  • I will continue to follow the research, adapting and offering the latest PRP injections while also ensuring that these new practices are both safe and effective. (prweb.com)
  • Part of SDWA required EPA to report back to Congress on waste disposal practices, and develop minimum federal requirements for injection practices that protect public health by preventing injection wells from contaminating underground sources of drinking water. (sourcewatch.org)
  • Some of the most common side effects of botched injections are severe allergic reactions and even ulcers around the injection site, according to Dr. Mark Abdelmalek, chief of the division of laser and dermatologic surgery at Drexel University College of Medicine in Philadelphia. (go.com)
  • tell your doctor and pharmacist if you are allergic to cabotegravir, rilpivirine, any other medications, or any of the ingredients in cabotegravir and rilpivirine injections. (medlineplus.gov)
  • Xolair injections work by binding to the IgE that is produced in allergic reactions and neutralizing its actions. (healthcentral.com)
  • Like all injections, there is a very small risk of bleeding, infection, or allergic reaction. (emoryhealthcare.org)
  • Although this is rare, there's always the possibility of an allergic reaction at the injection site, or even an infection. (healthcentral.com)
  • An allergic reaction to the medications used in the injection. (spine-health.com)
  • The fingersticks we use to measure our blood glucose levels hurt more than the injections because we prick our fingertips, which are full of pain-sensitive nerves. (healthcentral.com)
  • Dr. Warnock has begun using PRP injections as a treatment to help alleviate knee pain associated with early arthritis. (prweb.com)
  • American Academy of Family Physicians Family Doctor: "Osteoarthritis of the Knee: Hyaluronic Acid Injections. (webmd.com)
  • As a result of these study findings, knee specialist, Houston surgeon Dr. K. Mathew Warnock has begun using PRP injections in the treatment of early knee arthritis. (prweb.com)
  • PRP injections can help those who suffer from knee pain improve their quality of life and help those who are active feel less pain and enjoy their daily activities. (prweb.com)
  • Houston residents can now choose these injections to help improve the pain associated with early arthritis in the knee and other joints. (prweb.com)
  • The "trigger point" injection is done to a tendon area or into the bursa surrounding such joints as the shoulder, knee, or the hip. (spineuniverse.com)
  • GC precision mould Co., Ltd is an injection molders in China, offer the best quality China injection molding & molds, go to our home page which you can find detailed information of Plastic Injection Molding & molds service. (slideshare.net)
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  • Our organization is headed by Mr. Mahesh bhai Patel whose rich industry experience has helped us to emerge as one of the leading manufacturers of energy efficient plastic injection molding machine. (slideshare.net)
  • To determine the efficacy and safety of corticosteroid injections in the treatment of adults with shoulder pain. (nih.gov)
  • There is a need for further trials investigating the efficacy of corticosteroid injections for shoulder pain. (nih.gov)
  • Several studies have proven the efficacy of epidural steroid injections throughout the spine. (spine-health.com)
  • The ventrogluteal site (hip) is recommended for injections requiring a larger volume to be administered, greater than 1 ml, and for medications known to be irritating, viscous or oily. (wikipedia.org)
  • Before receiving your first cabotegravir and rilpivirine extended-release injections, you will have to take cabotegravir (Vocabria) and rilpivirine (Edurant) tablet orally (by mouth) once daily for one month (at least 28 days) to see if you can tolerate these medications. (medlineplus.gov)
  • Your doctor will probably tell you not to receive cabotegravir and rilpivirine injections if you are taking one or more of these medications. (medlineplus.gov)
  • These injections typically deposit steroids and/or other medications in the epidural space of the spine. (spine-health.com)
  • Denosumab injection (Xgeva) is used Denosumab injection is in a class of medications called RANK ligand inhibitors. (medlineplus.gov)
  • Steroid injections can be added to a treatment program that may already include analgesics (pain medications), anti-inflammatory medications, physical therapy, occupational therapy, and/or supportive devices such as canes and braces. (clevelandclinic.org)
  • Local injections are generally well-tolerated and are less likely to produce serious side effects than other forms of steroid medications. (clevelandclinic.org)
  • The contraceptive injection (Depo-Provera, Sayana Press or Noristerat) releases the hormone progestogen into your bloodstream to prevent pregnancy. (www.nhs.uk)
  • If used correctly, the contraceptive injection is more than 99% effective. (www.nhs.uk)
  • The contraceptive injection steadily releases the hormone progestogen into your bloodstream, which prevents the release of an egg each month (ovulation). (www.nhs.uk)
  • Most women can have a contraceptive injection. (www.nhs.uk)
  • Cabotegravir and rilpivirine injections are used in combination for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in certain adults. (medlineplus.gov)
  • Gold injection treatment must be used regularly for the best results. (medicalnewstoday.com)
  • Despite many RCTs of corticosteroid injections for shoulder pain, their small sample sizes, variable methodological quality and heterogeneity means that there is little overall evidence to guide treatment. (nih.gov)
  • Pentacarinat injection contains the active ingredient pentamidine isetionate, which is an antiprotozoal medicine used in the treatment of a number of protozoal infections. (netdoctor.co.uk)
  • Epidural steroid injections are a common treatment for neck and back pain. (spine-health.com)
  • Occasionally, epidural steroid injections are administered in a series of "two to three," depending on your physician's specific treatment plan for you. (emoryhealthcare.org)
  • When denosumab injection (Prolia) is used to treat osteoporosis or bone loss, your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with denosumab injection and each time you refill your prescription. (medlineplus.gov)
  • The last treatment I got there was trigger point injections (with steriods) that did not work at all. (healingwell.com)
  • Not all SI treatment injections are effective in the long-term. (spine-health.com)
  • Steroid injections are a type of treatment that delivers a high dose of medication directly to a problem spot in the body. (clevelandclinic.org)
  • What role do steroid injections play in an overall treatment program? (clevelandclinic.org)
  • A urethral bulking injection is one type of treatment for incontinence in women. (wikipedia.org)
  • Contraindications for this treatment are having a current urinary tract infection, having difficulty emptying the bladder, having a urethral stricture, having a urethral obstruction or having fragile or sensitive tissue where the injections are to be placed. (wikipedia.org)
  • Diagnostic joint injection, with or without a corticosteroid, can help determine whether shoulder pain involves the structures that lie within the subacromial space (ie, subacromial bursa or rotator cuff). (medscape.com)
  • Furthermore, subacromial injection is particularly helpful in differentiating between shoulder weakness caused by impingement, in which shoulder strength improves after injection, and a true rotator cuff tear (see the images below), in which no change in strength is noted after injection. (medscape.com)
  • Therapeutic joint injection provides pain relief and functional improvement in symptomatic subacromial impingement syndrome, rotator cuff disorders, and adhesive capsulitis. (medscape.com)
  • Epidural steroid injections may help relieve pain stemming from conditions such as spinal stenosis , foraminal stenosis , disc herniation , or degenerative disc disease . (spine-health.com)
  • Trigger point injections. (arthritis.org)
  • The cortisone/steroid injections, used in medical practice, fall into three broad categories, articular injections, "trigger point" injections, and epidural steroid injections. (spineuniverse.com)
  • It is neither a joint nor "trigger point" injection but, rather an injection inside the bony column of the spine surrounding the dura (the sac that encloses the spinal cord and spinal nerves). (spineuniverse.com)
  • I haven't started IVF injections yet, but I give myself Humira (RA drug) shot every week with the same needle we will be using for IVF and it doesn't hurt. (dailystrength.org)
  • Infection re humira and stopping injections? (drugs.com)
  • Silicone injections are among the most dangerous kinds of botched procedures, Roth said. (go.com)
  • We cannot adequately take care of silicone injections gone wrong," he added. (go.com)
  • Please complete the fields below to get your FREE copy of Dependency Injection. (manning.com)
  • With dependency injection, this pattern is inverted-a reference to a service is placed directly into the object which eases testing and modularity. (manning.com)
  • Spring or Google Guice use dependency injection so you can focus on your core application and let the framework handle infrastructural concerns. (manning.com)
  • Dependency Injection explores the DI idiom in fine detail, with numerous practical examples that show you the payoffs. (manning.com)
  • Dependency injection is not just for gurus - this book explains all. (manning.com)
  • The needle is then stabilized with the nondominant hand while the dominant hand slides to the plunger to slowly instill the medication, as a rapid injection causes more discomfort. (wikipedia.org)
  • The higher the guage the smaller the needle) wait until you get to the good stuff with the IM injections of progesterone with a 22g needle and 1 1/2 inches long! (dailystrength.org)
  • a hollow needle, as in injection. (britannica.com)
  • Transforaminal injection -the needle is inserted into the epidural space through the intervertebral foramen on the side of the spinal canal. (spine-health.com)
  • Interlaminar injection -the needle is inserted into the space between adjacent vertebral laminae (posterior wall of the vertebra) to reach the epidural space. (spine-health.com)
  • Your healthcare provider will use an X-ray machine showing moving images on a screen to guide the needle as he or she makes the injection and ensures that the needle is in the correct location. (hopkinsmedicine.org)
  • Sometimes doctors use injections or implanted devices to deliver pain relief medication locally instead of using oral pain drugs. (arthritis.org)
  • The SI joint is a complex anatomic region and the accuracy of the injection often determines the success of obtaining pain relief. (spine-health.com)
  • In the peri-articular technique, the exact location for the injection is unclear, with doctors suggesting injecting at varying depths to reach the desired amount of pain-relief. (spine-health.com)
  • Depending on the injection site, an administration is limited to between 2 and 5 milliliters of fluid. (wikipedia.org)
  • The deltoid muscle site (upper arm) is recommended for use with injections of small volume, usually equal or less than 1 ml, including vaccinations. (wikipedia.org)
  • This site is not recommended for repeated injections, due to its small area, it is difficult to rotate the injection site. (wikipedia.org)
  • The injection site is located by dividing the buttock into four with a plus (+) shaped cross, and administering the injection in the upper outer quadrant. (wikipedia.org)
  • The most common side effects are pain, swelling, or bruising at the injection site. (medlineplus.gov)
  • Indeed, after each of at least her first two injections, Wonder was patched up at her injection site with cotton balls and super glue to keep from leaking, she chronicled in her book. (go.com)
  • The number, site and dosage of injections varied widely between studies. (nih.gov)
  • Side effects can vary from person to person and may include: reactions at the site of injections, colds, sinus infections, headache and sore throat. (healthcentral.com)
  • SQL injection was also the attack vector in the recent hack of Chinese toy company VTE, in which the personal information of some 4.8 million parents and 200,000 children were stolen from the company's site. (wired.com)
  • There have even been suggestions that the Mossack Fonseca-the Panamanian law firm that was the source of the recent massive Panama Papers leak-had a SQL injection vulnerability on its web site , though it's not known if this is how the whistleblower who leaked the documents to media outlets obtained them. (wired.com)
  • have a skin infection at the planned injection site. (botoxcosmetic.com)
  • Bruising and/or soreness at the injection site. (spine-health.com)
  • Infection at the injection site, deeper tissues within the joint, or the pelvis. (spine-health.com)
  • If a patient has a potential bleeding problem or is taking anticoagulants (often referred to as blood thinners), steroid injections may cause bleeding at the site. (clevelandclinic.org)
  • Human Growth Hormone An recent article in the Harvard Health Publications of the Harvard Medical School, argues that "Adults with bona fide GH [growth hormone] deficiencies benefit from GH injections. (amazonaws.com)
  • This article on cortisone injections is quite informative and the information is accurate. (spineuniverse.com)
  • Steroid injections are one of the most effective ways to decrease pain and improve function, yet they generally do not cure the illness. (clevelandclinic.org)
  • Lidocaine is used to treat headache in other ways: for example, in nasal sprays and drops and injections into muscles. (medscape.com)
  • The cost of Xolair injections can range from $500-$2,000 per month depending on the frequency and dosage needed. (healthcentral.com)
  • California began executing prisoners by injection in 1996 after a federal appeals court ruled that San Quentin's gas chamber violated the Constitution's ban on cruel and unusual punishment. (latimes.com)
  • Had my last injection 3 months ago and never thought I'd say this but I wish my period would start cos I'm havin pain, pmt's etc, everything bar bleeding. (dailystrength.org)