Fluid propulsion systems driven mechanically, electrically, or osmotically that are used to inject (or infuse) over time agents into a patient or experimental animal; used routinely in hospitals to maintain a patent intravenous line, to administer antineoplastic agents and other drugs in thromboembolism, heart disease, diabetes mellitus (INSULIN INFUSION SYSTEMS is also available), and other disorders.
Implanted fluid propulsion systems with self-contained power source for providing long-term controlled-rate delivery of drugs such as chemotherapeutic agents or analgesics. Delivery rate may be externally controlled or osmotically or peristatically controlled with the aid of transcutaneous monitoring.
The long-term (minutes to hours) administration of a fluid into the vein through venipuncture, either by letting the fluid flow by gravity or by pumping it.
The administration of liquid medication, nutrient, or other fluid through some other route than the alimentary canal, usually over minutes or hours, either by gravity flow or often by infusion pumping.
Regional infusion of drugs via an arterial catheter. Often a pump is used to impel the drug through the catheter. Used in therapy of cancer, upper gastrointestinal hemorrhage, infection, and peripheral vascular disease.
Portable or implantable devices for infusion of insulin. Includes open-loop systems which may be patient-operated or controlled by a pre-set program and are designed for constant delivery of small quantities of insulin, increased during food ingestion, and closed-loop systems which deliver quantities of insulin automatically based on an electronic glucose sensor.
Freedom of equipment from actual or potential hazards.
Adjunctive computer programs in providing drug treatment to patients.
Process of administering an anesthetic through injection directly into the bloodstream.
An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
The therapeutic intermittent administration of oxygen in a chamber at greater than sea-level atmospheric pressures (three atmospheres). It is considered effective treatment for air and gas embolisms, smoke inhalation, acute carbon monoxide poisoning, caisson disease, clostridial gangrene, etc. (From Segen, Dictionary of Modern Medicine, 1992). The list of treatment modalities includes stroke.
Ultrashort-acting anesthetics that are used for induction. Loss of consciousness is rapid and induction is pleasant, but there is no muscle relaxation and reflexes frequently are not reduced adequately. Repeated administration results in accumulation and prolongs the recovery time. Since these agents have little if any analgesic activity, they are seldom used alone except in brief minor procedures. (From AMA Drug Evaluations Annual, 1994, p174)
Errors in prescribing, dispensing, or administering medication with the result that the patient fails to receive the correct drug or the indicated proper drug dosage.
Failure of equipment to perform to standard. The failure may be due to defects or improper use.
An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Interruption of NEURAL CONDUCTION in peripheral nerves or nerve trunks by the injection of a local anesthetic agent (e.g., LIDOCAINE; PHENOL; BOTULINUM TOXINS) to manage or treat pain.
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
Methods of creating machines and devices.
Pain during the period after surgery.
Organic compounds containing the -CO-NH2 radical. Amides are derived from acids by replacement of -OH by -NH2 or from ammonia by the replacement of H by an acyl group. (From Grant & Hackh's Chemical Dictionary, 5th ed)
Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.
The principal alkaloid in opium and the prototype opiate analgesic and narcotic. Morphine has widespread effects in the central nervous system and on smooth muscle.
The relationship between the dose of an administered drug and the response of the organism to the drug.
Compounds that inhibit H(+)-K(+)-EXCHANGING ATPASE. They are used as ANTI-ULCER AGENTS and sometimes in place of HISTAMINE H2 ANTAGONISTS for GASTROESOPHAGEAL REFLUX.
Elements of limited time intervals, contributing to particular results or situations.
A general class of integral membrane proteins that transport ions across a membrane against an electrochemical gradient.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.

Distinct clinical and laboratory activity of two recombinant interleukin-2 preparations. (1/472)

Interleukin-2 (IL-2) is a potent lymphokine that activates natural killer cells, T cells, and other cells of the immune system. Several distinct recombinant human IL-2 preparations have shown antitumor activity, particularly for renal cell cancer and melanoma. Somewhat distinct immune and clinical effects have been noted when different IL-2 preparations have been tested clinically; however, the regimens and doses used were not identical. To compare these more directly, we have evaluated two clinical recombinant IL-2 preparations in vitro and in vivo using similar regimens and similar IUs of IL-2. We used the Food and Drug Administration-approved, commercially available Chiron IL-2 and the Hoffmann LaRoche (HLR) IL-2 supplied by the National Cancer Institute. Using equivalent IUs of IL-2, we noted quantitative differences in vitro and in vivo in the IL-2 activity of these two preparations. In patients receiving comparable IUs of the two preparations, HLR IL-2 induced the release of more soluble IL-2 receptor alpha into the serum than Chiron IL-2. In addition, more toxicities were noted in patients receiving 1.5 x 10(6) IU of HLR IL-2 than were seen in patients treated with 1.5 x 10(6) or even 4.5 x 10(6) IU of Chiron IL-2. These toxicities included fever, nausea and vomiting, and hepatic toxicity. In vitro proliferative assays using IL-2-dependent human and murine cell lines indicated that the IU of HLR IL-2 was more effective than Chiron IL-2 at inducing tritiated thymidine incorporation. Using flow cytometry, we also found quantitative differences in the ability of these two preparations to bind to IL-2 receptors. These findings indicate that approximately 3-6 IU of Chiron IL-2 are required to induce the same biological effect as 1 IU of HLR IL-2.  (+info)

Efficacy of ampicillin plus ceftriaxone in treatment of experimental endocarditis due to Enterococcus faecalis strains highly resistant to aminoglycosides. (2/472)

The purpose of this work was to evaluate the in vitro possibilities of ampicillin-ceftriaxone combinations for 10 Enterococcus faecalis strains with high-level resistance to aminoglycosides (HLRAg) and to assess the efficacy of ampicillin plus ceftriaxone, both administered with humanlike pharmacokinetics, for the treatment of experimental endocarditis due to HLRAg E. faecalis. A reduction of 1 to 4 dilutions in MICs of ampicillin was obtained when ampicillin was combined with a fixed subinhibitory ceftriaxone concentration of 4 micrograms/ml. This potentiating effect was also observed by the double disk method with all 10 strains. Time-kill studies performed with 1 and 2 micrograms of ampicillin alone per ml or in combination with 5, 10, 20, 40, and 60 micrograms of ceftriaxone per ml showed a > or = 2 log10 reduction in CFU per milliliter with respect to ampicillin alone and to the initial inoculum for all 10 E. faecalis strains studied. This effect was obtained for seven strains with the combination of 2 micrograms of ampicillin per ml plus 10 micrograms of ceftriaxone per ml and for six strains with 5 micrograms of ceftriaxone per ml. Animals with catheter-induced endocarditis were infected intravenously with 10(8) CFU of E. faecalis V48 or 10(5) CFU of E. faecalis V45 and were treated for 3 days with humanlike pharmacokinetics of 2 g of ampicillin every 4 h, alone or combined with 2 g of ceftriaxone every 12 h. The levels in serum and the pharmacokinetic parameters of the humanlike pharmacokinetics of ampicillin or ceftriaxone in rabbits were similar to those found in humans treated with 2 g of ampicillin or ceftriaxone intravenously. Results of the therapy for experimental endocarditis caused by E. faecalis V48 or V45 showed that the residual bacterial titers in aortic valve vegetations were significantly lower in the animals treated with the combinations of ampicillin plus ceftriaxone than in those treated with ampicillin alone (P < 0.001). The combination of ampicillin and ceftriaxone showed in vitro and in vivo synergism against HLRAg E. faecalis.  (+info)

Phase I-II study of gemcitabine and fluorouracil as a continuous infusion in patients with pancreatic cancer. (3/472)

PURPOSE: To determine the maximum-tolerated dose (MTD), dose-limiting toxicities, and efficacy of gemcitabine combined with fluorouracil (5-FU) in patients with pancreatic cancer. PATIENTS AND METHODS: Patients with measurable, locally advanced, nonresectable or metastatic pancreatic cancer were candidates for the study. 5-FU was given via protracted venous infusion (PVI) at a fixed dosage of 200 mg/m2/d, and gemcitabine was administered weekly for 3 consecutive weeks every 4 weeks. The initial dose of gemcitabine was 700 mg/m2 and was escalated in increments of 100 mg/m2/wk until the appearance of severe toxicity. Measurements of efficacy included the following: response rate; clinical benefit response, which is a composite measurement of pain, performance status, and weight loss; time to disease progression; and survival. RESULTS: Twenty-six patients received a total of 109 courses. Dose-limiting toxicity, which consisted of grade 4 neutropenia with fever (one patient) and grade 4 thrombocytopenia (one patient), was observed in two of three patients treated with 1,100 mg/m2/wk of gemcitabine. On the basis of these results, the MTD of gemcitabine with 5-FU via PVI on this schedule was 1,000 mg/m2. Sixteen patients developed grade 3-4 neutropenia, and three patients developed grade 3-4 thrombocytopenia. Grade 3-4 nonhematologic toxicity consisted of diarrhea (two patients) and cutaneous toxicity, asthenia, edema, mucositis, and nausea and vomiting (one patient each). The delivered dose-intensity of gemcitabine was similar at the 1,000 mg/m2 dose level (599 mg/m2/wk) as at the 900 mg/m2 (601 mg/m2/wk) dose level. For this reason, the recommended dose of gemcitabine for phase II evaluation on this schedule was 900 mg/m2. Five patients had objective responses (one complete response and four partial responses; response rate, 19.2%; 95% confidence interval [CI], 6.5 to 39.3), and 10 patients had improvement of disease-related symptoms (45%; 95% CI, 24 to 67). After a median follow-up of 17.7 months (range, 7.8 to 24.8 months), the median progression-free survival and overall survival times were 7.4 months (95% CI, 3.3 to 11.4) and 10.3 months (95% CI, 8.1 to 12.5), respectively. CONCLUSION: The MTD of gemcitabine when combined with 5-FU via PVI on this schedule was 1,000 mg/m2/ wk; however, on the basis of administered dose-intensity, the recommended dose for additional investigation is 900 mg/m2. This combination chemotherapy regimen was well tolerated and showed promising antitumor activity in the treatment of pancreatic cancer.  (+info)

The effects of vapreotide, a somatostatin analogue, on gastric acidity, gallbladder emptying and hormone release after 1 week of continuous subcutaneous infusion in normal subjects. (4/472)

AIMS: Somatostatin analogues (e.g. vapreotide) are used for treatment of acromegaly, endocrine tumours and variceal bleeding. The pharmacodynamic effects of vapreotide have, however, not been documented in the gastrointestinal tract. The aim of this study was to investigate the effects of continuous vapreotide administration on gastric acidity, gallbladder contraction and hormone release. METHODS: Ten healthy males participated in this randomised, placebo-controlled, double-blind, crossover trial. A constant vapreotide (or placebo) infusion (1.5 mg day(-1) s.c.) was given for 7 days with a portable pump. Intragastric pH was monitored on days 2 and 7. Gallbladder volume was sonographically assessed and the maximal ejection fraction was calculated. In addition basal and postprandial plasma levels of gastrin and cholecystokinin (CCK) were measured. RESULTS: After an initial increase in the median 24 h intragastric pH to a value of 2.6 on day 2, vapreotide's effect on pH decreased: (day 7: median pH=1.9; respective placebo values were 1.7 and 1.5). On the same days with vapreotide treatment, gallbladder contraction and plasma levels of CCK were reduced; maximal ejection fractions after meal stimulation were 18% and 20% (respective placebo values were 57% and 62%). Plasma gastrin levels were not changed with vapreotide treatment. CONCLUSIONS: The short lasting effect of vapreotide on intragastric acidity suggests a down-regulation of somatostatin receptors during treatment. The lack of effect on gastrin indicates that the effects on gastric pH are not mediated by gastrin. Constant vapreotide infusion (but not placebo) reduced gallbladder contraction suggesting a long-lasting effect on biliary function.  (+info)

Self-intoxication with morphine obtained from an infusion pump. (5/472)

A 36-year-old Caucasian male was found unresponsive by his wife. He had white foam around his mouth and was pronounced dead shortly thereafter. He had a history of back pain and was treated with intrathecal morphine because of his previous addiction to oral opiate medications. Because of crimping of the pump catheter, it was replaced 4 days before his death. Toxicological findings included urine screen positive for amitriptyline, nortriptyline, opiates, hydrocodone metabolites, ibuprofen, acetaminophen, caffeine, nicotine, and metabolite. Drug concentrations were as follows: blood, 0.260 mg/L amitriptyline, 0.160 mg/L nortriptyline, 0.460 mg/L unconjugated morphine, and 0.624 mg/L total morphine; vitreous humor, 0.034 mg/L unconjugated morphine and 0.080 mg/L total morphine; and cerebrospinal fluid, 0.099 mg/L unconjugated morphine and 0.095 mg/L total morphine. Shortly after death, the volume of the residual pump reservoir was only 8 mL instead of the expected 17 mL. Testing by the FDA showed that the pump was functional. The residual content of the pump accounted for only 230 mg instead of the expected 488 mg. The high blood-morphine concentrations did not correlate with the intrathecal infusion dose. The symptoms were consistent with opiate overdose, possibly by injection of morphine withdrawn from the pump reservoir. The cause of death was determined to be fatal morphine self-intoxication, and the manner of death was accidental. This case is intended to alert regulatory agencies, pain management health professionals, pathologists, and toxicologists to the abuse potential of one of the newer analgesic-delivery systems.  (+info)

Glutamate augments retrovirus-induced immunodeficiency through chronic stimulation of the hypothalamic-pituitary- adrenal axis. (6/472)

The mechanisms for activating the hypothalamic-pituitary-adrenal (HPA) axis and the roles glucocorticoids play in the pathogenesis of chronic infectious disease are largely undefined. Using the LP-BM5 model of retrovirus-induced immunodeficiency, we found alterations in HPA axis function, manifested as an increase in circulating levels of adrenocorticotropic hormone and corticosterone, beginning after only 3 mo of infection. These changes occurred contemporaneously with a shift in the profile of circulating cytokines from a Th1-dominant (IFN-gamma) to Th2-dominant (IL-4, IL-10) phenotype. No significant changes in either circulating IL-1beta, IL-6, or TNF-alpha levels were observed in infected mice. Administering the N-methyl-D-aspartate receptor antagonist MK-801 to infected mice normalized plasma adrenocorticotropic hormone and corticosterone levels, indicating that glutamate was a major activator of the HPA axis. Moreover, MK-801 treatment of late-stage mice also reversed the type 1 to type 2 cytokine shift to a degree comparable or superior to treatment with the glucocorticoid receptor antagonist RU-486. These findings indicate that HPA axis activation during LP-BM5 retrovirus infection is mediated by the chronic hyperactivation of glutamatergic pathways in the hypothalamus. Through this mechanism, the degree of peripheral immunodeficiency observed in the late-stage disease is profoundly augmented.  (+info)

Enhancement of locomotor activity and conditioned reward to cocaine by brain-derived neurotrophic factor. (7/472)

The mesolimbic dopamine (DA) system has been implicated in drug reward, locomotor sensitization, and responding for reward-related stimuli [termed conditioned reinforcers (CR)]. Here, we investigated the effect of brain-derived neurotrophic factor (BDNF), which enhances the survival and function of dopaminergic neurons, on stimulant-induced locomotor sensitization and responding for CR. In experiment 1, BDNF was infused into the nucleus accumbens (NAc) or ventral tegmental area over 2 weeks via chronically implanted minipumps (1-2.5 microgram/d), and the psychomotor stimulant effects of cocaine (5-15 mg/kg, i.p.) were studied. We found that BDNF enhanced the initial stimulant effects of cocaine and seemed to facilitate the development of sensitization to repeated cocaine doses. In experiment 2, we studied the effects of intra-NAc BDNF infusions on responding for CR. BDNF-treated rats showed twice as many CR responses compared with controls when saline was first administered. BDNF enhanced responding on the CR lever more than four times that seen in control animals after a cocaine injection (10 mg/kg, i.p.). The enhanced response to cocaine in BDNF-treated animals persisted for more than a month after the BDNF infusions had stopped, indicating long-lasting changes in the mesolimbic DA system caused by BDNF administration. In experiment 3, we examined locomotor sensitization to cocaine in heterozygous BDNF knock-out mice and found that the development of sensitization was delayed compared with wild-type littermates. These results demonstrate the profound effects of BDNF on the enhancement of both cocaine-induced locomotion and facilitation of CR and suggest a possible role for BDNF in long-term adaptations of the brain to cocaine.  (+info)

Comparison of recovery of propofol and methohexital sedation using an infusion pump. (8/472)

Two sedative anesthetic agents administered by an infusion pump were compared during third molar surgery. Forty American Society of Anesthesiologists (ASA) class I or II volunteers were randomly allocated to two groups. All subjects received supplemental oxygen via a nasal hood, fentanyl (0.0007 mg/kg intravenous [i.v.] bolus), and midazolam (1 mg/2 min) titrated to effect. Patients then received either 0.3 mg/kg of methohexital or 0.5 mg/kg of propofol via an infusion pump. Upon completion of the bolus, a continuous infusion of 0.05 mg/kg/min methohexital or 0.066 mg/kg/min propofol was administered throughout the procedure. Hemo-dynamic and respiratory parameters and psychomotor performance were compared for the two groups and no significant differences were found. The continuous infusion method maintained a steady level of sedation. Patients receiving propofol had a smoother sedation as judged by the surgeon and anesthetist.  (+info)

Postoperative pain is typically managed with pain medication, which may include opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), or other types of medications. The goal of managing postoperative pain is to provide effective pain relief while minimizing the risk of complications such as addiction, constipation, or nausea and vomiting.

In addition to medication, other techniques for managing postoperative pain may include breathing exercises, relaxation techniques, and alternative therapies such as acupuncture or massage. It is important for patients to communicate with their healthcare provider about the severity of their pain and any side effects they experience from medication, in order to provide effective pain management and minimize complications.

Postoperative pain can be categorized into several different types, including:

* Acute pain: This type of pain is intense but short-lived, typically lasting for a few days or weeks after surgery.
* Chronic pain: This type of pain persists for longer than 3 months after surgery and can be more challenging to manage.
* Neuropathic pain: This type of pain is caused by damage to nerves and can be characterized by burning, shooting, or stabbing sensations.
* Visceral pain: This type of pain originates in the internal organs and can be referred to other areas of the body, such as the back or abdomen.

Specialized infusion pumps have been designed for this purpose, although they have not been deployed. Many infusion pumps are ... called the Infusion Pump Improvement Initiative.[3] The initiative proposed stricter regulation of infusion pumps. It cited ... Safety issues Infusion pumps have been a source of multiple patient safety concerns, and problems with such pumps have been ... Osmotic pumps are usually recharged with a syringe. Spring-powered clockwork infusion pumps have been developed, and are ...
Examples of infusion devices include smart pumps, syringe pumps and target-controlled infusion (TCI) devices. Smart pumps are ... Syringe pumps are smaller infusion pumps that allow the administration of small amounts of induction agents at a precise rate. ... The accuracy of syringe pumps is dependent on the selection of syringes during pump programming. Most pumps are able to ... Smart pumps are advantageous since they administer safe doses with a programmed infusion rate within pre-existing limits based ...
February 1988). "Testing computer-controlled infusion pumps by simulation". Anesthesiology. 68 (2): 261-6. doi:10.1097/00000542 ... 1988). "Pharmacokinetics and pharmacodynamics of propofol infusions during general anesthesia". Anesthesiology. 69 (3): 348-356 ...
"VDOCKS Visual Docking Guidance System" (PDF). "Infusion Pump Reads Bar Codes". May 1, 2002. "Paragon Innovations gets Contract ... system that provides precise guidance information for pilots during the docking process for Siemens An automated infusion pump ...
Applications include mobile phones, cordless phones, pagers; medical devices such as diagnostic equipment and infusion pumps; ...
Raj, Phulchand (1979). "Experience with volumetric infusion pumps for continuous epdural analgesia". Reg Anesth. 4: 3-5. (Pages ... sciatic-femoral nerve block Physiology and pharmacokinetics of continuous infusions Experience with volumetric infusion pumps ... Raj, Phulchand (1997). "Physiology and pharmacokinetics of continuous infusions". Pain Digest. 7: 51-61. ...
In 2010, Baxter was ordered by the FDA to recall all of their Colleague infusion pumps from the market due to 87 recalls and ... "FDA Issues Statement on Baxter's Recall of Colleague Infusion Pumps". FDA. FDA. Retrieved May 3, 2010. Portero, Ashley. "30 ... Caremark was fined $160 million for the "four-year-long federal mail-fraud and kickback" scheme in which the "home-infusion ... Baxter's home infusion subsidiary, Caremark, "was accused by the government of paying doctors to steer patients to its ...
Intrathecal pumps periodically need to be replaced. For baclofen pumps, this may be once every 5-7 years. Infusion pump ... Two types of pumps are available: a constant rate pump delivers the medication at a constant rate, and a programmable pump ... Intrathecal pumps require maintenance. Individuals who use these pumps will need to come into their physician's office to have ... The implantable intrathecal pump consists of a metal pump which stores and delivers the medication, and an intrathecal catheter ...
... equipment includes infusion pumps, medical lasers, and LASIK surgical machines; medical monitors allow medical staff to measure ...
Treatment equipment includes infusion pumps, medical lasers and LASIK surgical machines. Life support equipment is used to ... Examples of Class II devices include acupuncture needles, powered wheelchairs, infusion pumps, air purifiers, surgical drapes, ... FDA (2010-09-08). "Infusion Pump Software Safety Research at FDA". FDA. Retrieved 2010-09-09. Zuckerman, Diana (2011), "Medical ... Insulin Pumps Vulnerable to Attacks by Hackers Daily Tech June 15, 2011 Nidhi Subbaraman Daily Tech June 15, 2011 Nidhi ...
FDA (2010-09-08). "Infusion Pump Software Safety Research at FDA". Food and Drug Administration. Archived from the original on ...
These risks can often be minimized by keeping infusion sites clean. Insulin pumps require care and effort to use correctly.[ ... In type 1 diabetics, it may also be achieved via continuous infusion of rapid-acting insulin using an insulin pump. ... This calculation may also be performed by an insulin pump in patients using a pump. Insulin regiments that consist of doses ... and calculators in the pump that may help with determining bolus infusion dosages. The limitations are cost, the potential for ...
Infusion Set in a diabetic context, a tubing system to connect an insulin pump to the pump user, including a subcutaneous ... Insulin pump a device which provides a steady (or intermittent, depending on design and adjustments) infusion of insulin. Pumps ... Continuous subcutaneous insulin infusion (CSII) See: Insulin pump. Contraindication A condition that makes a treatment not ... Implantable insulin pump An insulin pump that is implantable rather than external. A small device placed inside of the body ...
These include ventilators, infusion pumps, surgical and dental instruments, imaging and beds. Electronics portal Energy portal ... This refers to conveyors, assembly lines, bar code readers, cameras, motors, pumps, semi-fabricated manufacturing and more. ...
Vasoactive drugs are typically administered using a volumetric infusion device (IV pump). This category of drugs require close ...
... ceased production of its Alaris SE infusion pump after approximately 1300 units were seized[why?] by the United ... "Cardinal Health Suspends Production of Alaris SE Infusion Pump Following FDA Actions". Cardinal Health. August 28, 2006. ...
These pumps are stimulated in the presence of food to aid in digestion. For this reason, patients should be advised to take ... "Omeprazole 40 mg Powder for Solution for Infusion". EMC. 10 February 2016. Archived from the original on 7 April 2016. ... "Proton Pump Inhibitor: Use in Adults" (PDF). CMS Medicaid Integrity Program. Archived from the original (PDF) on 12 December ... Omeprazole is a proton-pump inhibitor (PPI) and its effectiveness is similar to other PPIs. It can be taken by mouth or by ...
These pumps are guided by ISO28620 Infusion pump Syringe pump "Iso 28620:2020". (Articles needing additional references from ... Filling the pump is done manually through a one-way valve using a syringe or peristaltic repeater pump. Elastomeric pumps are ... Depending on the pump's size the drug inside the pump can be delivered over a time spread varying between thirty minutes to ... Elastomeric pumps - also called balloon pumps - are usually used in the medical field to administer liquid drugs such as local ...
Today insulin pumps are so small that they can fit in a pocket or a purse. In 1984 an Infusaid implantable infusion device was ... Insulin pumps, cartridges, and infusion sets may be far more expensive than syringes used for insulin injection with several ... Insulin Pumps Diabetes.co.uk guide to insulin pumps available in the UK Diabetes Educator - Insulin pump therapy:Best practices ... An extended bolus is a slow infusion of insulin spread out over time. By pumping with a "square wave" shape, the bolus avoids a ...
Phototherapy Units, Cardiac Monitors and Infusion Pumps are available for the patients care. The 53.8 Acres of land was ...
Diazoxide is given by mouth, octreotide by injection or continuous subcutaneous pump infusion. When congenital hyperinsulinism ... Even after pancreatectomy, continuous glucose may be needed in the form of gastric infusion of formula or dextrose. High dose ...
Animas is leading manufacturer of insulin infusion pumps located in West Chester, PA. From 1988 to 1996, Crothall was president ... She founded Animas Corporation (NASDAQ: PUMP) in 1996 and served as its president, CEO and chairman from its inception to its ...
The unit incorporates a ventilator, oxygen and suction capability, monitors and infusion pumps. The development of this concept ...
Electronic Pump: Drugs are often pre-mixed from vials and stored in infusion bags to be delivered by electronic pump. ... Elastomeric pump Pre-Filled Infusion Therapy: with this latest technology, a unit dose can be metered to the location from a ... A special infusion pump can be used for this purpose. A fenestrated catheter is most frequently inserted into the localized ... "US FDA/CDRH: Brochure - Home Healthcare Medical Devices: Infusion Therapy - Getting the Most Out of Your Pump". www.fda.gov. ...
Propofol is used intravenously via infusion pump for sedation. A consent form must be signed and received from the patient or ...
The infusion set can remain in the place for three days while the pump is clip-belt worn. There is a quick-disconnect feature ... MiniMed 504 Insulin Pump 1992 - Launch Of MiniMed 506 Insulin Pump 1996 - Introduction of MiniMed 507 Pump 1999 - Launch of the ... The pump operates with a single AA battery and uses a piston-plunger pump to infuse a programmed amount of insulin into the ... So any change in basal or bolus is patient-driven by programming the pump using the Bolus Wizard. The latest model pumps are ...
The infusion tubing and cannula must be removed and replaced every few days. An insulin pump can be programmed to infuse a ... It carries the insulin from the pump to the infusion site beneath the skin. It sends a larger amount before eating meals as " ... An injection port is a small disposable device, similar to the infusion set used with an insulin pump, configured to accept a ... The insulin pump is one device used in intensive insulinotherapy. The insulin pump is about the size of a beeper. It can be ...
Intravenous anesthetic is delivered either by bolus doses or an infusion pump. There are also many smaller instruments used in ... Nerve blocks are also used as a continuous infusion, following major surgery such as knee, hip and shoulder replacement surgery ... as a continuous infusion or "freezing" a tooth). The effect is almost immediate. Peripheral nerve block: local anesthetic is ...
An infusion set is used with devices such as an insulin pump. The purpose of an infusion set is to deliver insulin under the ... Often a number of favorite sites for the infusion set are used on a rotation basis. The set can be disconnected from the pump ... It is a complete tubing system to connect an insulin pump to the pump user and as such includes a subcutaneous cannula, ... or when engaging in any activity when it is not desirable to be attached to the pump. "What is an Infusion Set? :: Diabetes ...
... referring to the drug infusion pump that Davide was hooked up to. Growing up in a cultivated environment, Sorrenti painted, ...
The initial rate of infusion is generally around 200-300 mL/h in people not experiencing edema then it is adjusted to maintain ... such as acid-reducing drugs like H2-receptor antagonists or proton pump inhibitors. These new drugs replaced Sippy's diet ...
He also invented the first implantable infusion pump, a precursor to implantable infusion pumps in use throughout the world ... These include the world's first infusion port, peritoneovenous shunts, and specialty vascular catheters. ...
His free throw attempts had dropped from his career average, and his game had become over-reliant on pump fakes and long-range ... promoting Spalding's new NBA Infusion Ball, Upper Deck, Italian chocolate company Ferrero SpA's brand Nutella, Russell ...
... regulate the infusion of I.V. fluids, through an I.V. infusion pump, and drive the blood glucose level towards a predetermined ... presented a complex set of orders for determining the basal insulin requirements in pediatric patients using an insulin pump. ...
Infusion pump - Instrumentation for medical devices - Laser applications in medicine - Magnetic resonance imaging - Maxillo- ...
Deeb A, Abdelrahman L, Tomy M, Suliman S, Akle M, Smith M, Strauss K. Impact of Insulin Injection and Infusion Routines on ... Utilization and Challenges of Continuous Glucose Monitoring in Sensor-Augmented Pump Therapy: A Patient Experience Analysis. J ...
Gastric lavage (stomach pumping) or whole bowel irrigation are also not recommended. Enhancing elimination of the drug with ... Bradycardia is treated with atropine or an infusion of norepinephrine to increase coronary blood flow and heart rate. ...
Chemical lesions - Neural tissue is destroyed by the infusion of a neurotoxin. Temporary lesions - Neural tissue is temporarily ... Bacterial Halorhodopsins or Proton pumps are the two classes of proteins used for inhibitory optogenetics, achieving inhibition ... "High-performance genetically targetable optical neural silencing by light-driven proton pumps." Nature. Vol 463. 7 January 2010 ...
The ABCB11 gene encodes for the bile salt export pump (BSEP) protein, and the ABCB4 gene encodes for the multidrug resistance 3 ... In an open-label study, six patients that were unresponsive to UDCA had improvement in ALP levels after rituximab infusions. ... E2 secreted into the canaliculi by MRP2 was found to repress the transcription of bile salt export pump (BSEP), the apical ABC ...
... the catheters are connection to an infusion pump which is used to create the pressure gradient for bulk flow. Infusion rates ...
Since there is a lack of a right ventricle, there must also be a way to pump blood into the pulmonary artery. This can be ... "Long-Term Prostaglandin E1 Infusion for Newborns with Critical Congenital Heart Disease". Pediatric Cardiology. Hoffman Julien ... since it must pump blood to both the pulmonary and systemic systems) Normal or mildly enlarged heart Tricuspid atresia is ...
... pumping speed) ISO 1608-2:1989 Part 2: Measurement of critical backing pressure ISO 1609:2020 Vacuum technology - Dimensions of ... Transfusion sets for single use with pressure infusion apparatus ISO 1136:2015 Wool - Determination of mean diameter of fibres ... pumping speed) [Withdrawn: replaced with ISO 21360-2] ISO 1607-2:1989 Part 2: Measurement of ultimate pressure [Withdrawn: ... Covers for deck openings for pumps [Withdrawn without replacement] ISO/R 42:1957 Shipbuilding - Inland vessels - Mushroom-type ...
"Symbiq Infusion System by Hospira: FDA Safety Communication - Cybersecurity Vulnerabilities". fda.gov. "Researcher: Drug Pump ... "Hospira LifeCare PCA Infusion System Vulnerabilities (Update B) - ICS-CERT". us-cert.gov. "Billy (BK) Rios". xs-sniper.com. " ... This was followed in July 2015 by a second FDA recommendation that hospitals discontinue use of the affected pumps entirely. ... "ICU Medical Completes the Acquisition of Hospira Infusion Systems from Pfizer". ICU Medical. ICU Medical. Retrieved 28 April ...
Infusion pumps, Anesthesia, Laboratory, Dialysis, Respiratory services (ventilators), Gas therapy equipment Computer networking ...
If a crystalloid like normal saline (NS) is used, the infusion amount should be triple what is removed as the 3:1 ratio of ... To stop the blood from coagulating, anticoagulant is automatically mixed with the blood as it is pumped from the body into the ... The reversed line connections may not be visually apparent in the monitor box, and could result in excessive ACD infusion and ...
... is available in a portable infusion pump that provides pulsatile subcutaneous administration of the drug. The usual ... Micropump infusion of gonadorelin in the treatment of hypogonadotropic hypogonadism in patients with pituitary stalk ...
The government pumped ₹32 billion (US$400 million) into Air India in March 2012. On 1 March 2009, Air India made Frankfurt ... In 2013, the Indian government planned to delay equity infusion of ₹300 billion (US$3.8 billion) that was slated to be infused ...
Reduced ventricular functioning limits the ability of the ventricles to fill with blood and pump blood to the rest of the body ... Wang, Mengjun; Reza Mazhari; Itamar Ilsar; Alice Wang; Michael Sabbah; Hani Sabbah (2009). "Intravenous Infusion of CXL-1020, a ... Sarcoplasmic reticulum CaATPase (SERCA) is an energy-dependent ion pump found the sarcoplasmic reticulum of cardiac myocytes ...
... can be given subcutaneously by continuous infusion using an infusion set connected to an infusion pump, but also ... may be administered as a continuous subcutaneous infusion or continuous intravenous infusion via a small infusion pump that the ... Abrupt cessation of infusion should be avoided. Restarting a Remodulin infusion within a few hours after an interruption can be ... It may be administered as a continuous subcutaneous infusion or continuous intravenous infusion; however, because of the risks ...
Bendamustine Rapid Infusion as therapy for CLL and NHL is part of Teva's specialty drugs pipeline. TEV-44229 (renamed RXDX-108 ... "Teva snaps up Gecko and its 'smart inhaler' to pump up respiratory meds". FiercePharma.com. "Teva, Heptares Launch Up-to-$410M+ ...
Users of the subreddits r/CryptoCurrency and r/SatoshiStreetBets attempted to pump up Dogecoin to make it "the next GME/Bitcoin ... "Robinhood gets $1 billion infusion, signaling cash crunch". CNN. Archived from the original on January 29, 2021. Retrieved ... Kharpal, Arjun (January 28, 2021). "Reddit frenzy pumps up Dogecoin, a cryptocurrency started as a joke, by over 800%". CNBC. ... Ponciano, Jonathan (January 27, 2021). "Not Just GameStop: Here Are The Meme Stocks WallStreetsBets Traders Are Pumping Up ...
A volumetric infusion pump is used for slow administration (0.5 mL/min for the initial 30 minutes) to minimize the possibility ... of BAT is administered to a patient as an intravenous infusion. It must be diluted with 0.9% sodium chloride in a 1:10 ratio ...
For example, a risk-rating system might rate defibrillators as considered high risk, general-purpose infusion pumps as medium ...
... an insulin pump (based on the drug infusion pump technology),: 19 and an all-terrain electric wheelchair known as the iBOT, ... In April 2002, Kamen was awarded the Lemelson-MIT Prize for inventors, for his invention of the Segway and of an infusion pump ... Kamen was already a successful inventor: his company Auto Syringe manufactures and markets the first drug infusion pump.: 13 ... after five years of private advanced research for the insulin pump AutoSyringe. Kamen is best known for inventing the product ...
When the set-up is ready, the aorta is clamped shut with a cross-clamp to stop blood pumping through the heart and cardioplegia ... Stress echocardiography (i.e. with dobutamine infusion) can help determine if the ventricle is dysfunctional because of aortic ... The first attempts were valvotomies, (i.e. cutting the valve while the heart is pumping). A ball valve prosthesis placed on the ... This machine breathes for the patient and pumps their blood around their body while the surgeon replaces the heart valve.[ ...
In selected patients, either endoscopic therapy or selective infusion of vasopressin into the left gastric artery may help ... Alhazzani, W; Alenezi, F; Jaeschke, RZ; Moayyedi, P; Cook, DJ (Mar 2013). "Proton pump inhibitors versus histamine 2 receptor ... Possible agents include antacids, H2-receptor blockers, sucralfate, and proton pump inhibitors (PPIs). Tentative evidence ...
This intelligent infusion device solution can accurately control the number of infusion drops or infusion flow rate to ensure ... An infusion pump is an instrument that can accurately control the number of infusion drops or infusion flow rate to ensure that ... This solution is an intelligent infusion device. High stability and high accuracy guarantee medical safety. Long battery ...
Pump, infusion - Product Code FRN. Product. Plum A+3 Infusion Pump. List Number 12391. The Plum A+ Infusion Systems are a multi ... The Plum A+ family infusion pumps are self-contained, microprocessor based infusion devices.. ...
... using infusion pumps, i.e., comparable to patients using infusion pumps. Because hypoglycemia is rarely given as the underlying ... Insulin infusion pumps are open loop devices that administer insulin subcutaneously at a constant low level and deliver added ... While none of the deaths could be attributed to the infusion pumps, some deaths may have been due to the intensive glycemia ... Epidemiologic Notes and Reports Deaths among Patients Using Continuous Subcutaneous Insulin Infusion Pumps -- United States ...
But continuing the infusion without knowing how to manage the pump may not be a clinically appropriate or safe alternative ... Ambulatory Pump Safety: Managing Home Infusion Patients Admitted to the ED And Hospital ... Since then, the availability of lightweight ambulatory pumps has made infusion therapy possible in alternative settings outside ... Home infusion: A safety guide for patients and caregivers. 2013.. * Carson SL. Patient-supplied medication infusion devices in ...
... implantable pump. Among 55 patients treated with IA FUDR (0.3- … ... Toxicities and complications of implanted pump hepatic arterial and intravenous floxuridine infusion D C Hohn, A A Rayner, J S ... Hepatic artery infusion pumps. Thiels CA, DAngelica MI. Thiels CA, et al. J Surg Oncol. 2020 Jul;122(1):70-77. doi: 10.1002/ ... Toxicities and complications of implanted pump hepatic arterial and intravenous floxuridine infusion D C Hohn et al. Cancer. ...
A tab is provided to release the preloaded spring to impose a biasing force on the piston of the pump. The piston slides within ... the spring and the stroke of the piston are coordinated so as to maintain a pressure on the fluid being dispensed from the pump ... The ambulatory infusion pump is provided with a preloaded spring having a fixed spring constant. ... Justia Patents Spring Drives PistonUS Patent for Ambulatory infusion pump Patent (Patent # 5,100,389) Ambulatory infusion pump ...
Infusion Pumps. Acail Angola Health / Medical Equipment / Infusion Pumps Di2000 Volumetric Infusion .... Compact Design; Single ... Ms2200 Syringe Pump. Easy to use; Compatible with the main syringe brands; Capacity from 10 to 100ml; Maximum infusion rate: ... Sp5 Syringe Pump. High flow rate accuracy is achieved: within ±2%; Dedicated Mindray infusion sets be used delivering high ac ... Vp5 Infusion Pump. Compact design; 3.5" large colour display; User selectable eight levels of screen brightness, providing opt ...
We produce infusion pump with high accuracy and durable life ... high quality infusion pump factory. 8 Years Experience. CE, ISO ... Purge when pump stops, bolus when pump starts, rate at 700 ml/h ...
Usability of volumetric infusion pumps in pediatric intensive care. Usability of volumetric infusion pumps in pediatric ... To analyze the usability of two infusion pump models in a Pediatric Intensive Care Unit. METHOD:. This is a cross-sectional ... A task was carried out in a controlled environment using infusion pump with 72 nursing staff members from August to September ... The infusion pump-2 model was associated (p < 0.001) with operationalization, tasks accomplished with non-conformities, use of ...
This One-channel Volumetric Infusion Pump is design ergonomically and user friendly.It has touchable keypad and FND displays ... Zerone Volumetric Infusion Pump remove. Sonoscape P50 Ultrasound Machine remove. Sonoscape S22 Ultrasound Machine remove. DrGem ... Zerone Volumetric Infusion Pump remove. Sonoscape P50 Ultrasound Machine remove. Sonoscape S22 Ultrasound Machine remove. DrGem ... This Volumetric Infusion Pump has visual and audio alarm function and safety function. When the keypad is lock, all keys wont ...
Post-pandemic Era) - Global Medical Intravenous Infusion Pump Market Segment Research Report 2022 is a market research report ... BD Medical Intravenous Infusion Pump Product Introduction. Table 62. BD Medical Intravenous Infusion Pump Sales (Unit), Revenue ... Moog Medical Intravenous Infusion Pump Product Introduction. Table 86. Moog Medical Intravenous Infusion Pump Sales (Unit), ... Zoll Medical Intravenous Infusion Pump Product Introduction. Table 99. Zoll Medical Intravenous Infusion Pump Sales (Unit), ...
Infusion Therapy Market: Global Industry Analysis, Trends, Market Size, and Forecasts up to 2026 report... ... Infusion Therapy Market: Global Industry Analysis, Trends, Market Size, and Forecasts up to 2026 report... ... Infusion Pumps. 5.3. Needless Connectors. 5.4. IV Cannuals. 5.5. Others. 6. Global Infusion Therapy Market by Application. 6.1 ... 8.4.2. RoW Infusion Therapy Market by Application. 8.4.3. RoW Infusion Therapy Market by End User. 8.4.4. RoW Infusion Therapy ...
... the global infusion pump market was valued at around U ... The global infusion pump market size is expected to reach USD ... Infusion Pump Market Growth Infusion Pump Market Size Infusion Pump Market Trends ... Home/Healthcare/Infusion Pump Market Size to Worth Around US$ 24.6 Billion by 2030. HealthcarePress Releases Infusion Pump ... Infusion Pump Market Report Scope. A recent study by Precedence Research on the infusion pump market offers a forecast for 2022 ...
We are Chinas top quality Micro Syringe Pump manufacturer in Shanghai, China at latest price. ... In the year 2016, we launched AIO Pump, which is one of the milestones in the history of Infusion Pumps. We have patented ... LINSZ-10 Series AIO Pump *LINSZ-10B AIO Pump (I Infusion And I Syringe) ... Promising Quality In Our LINSZ-10 Series AIO Pump, LINZ-9 Series Micro Syringe Pump, LINZ-8 Series Micro Syringe Pump, etc. ...
Implantable Intravenous Infusion Pump: Use an implantable intravenous infusion pump approved for use with Treprostinil ... using an infusion pump designed for subcutaneous drug delivery. The infusion pump should:(1) be adjustable to approximately ... Chronic intravenous infusions delivered using an external infusion pump with an indwelling central venous catheter are ... Intravenous Infusion. External Intravenous Infusion Pump:. Treprostinil injection is administered intravenously by continuous ...
FDA, CISA Warn of Fresenius Kabi Infusion Pump Flaws. December 27, 2021 ...
To do so, mount an epidural infusion pump (see image below) with a bag containing 250 mL of epidural analgesic mixture ( ... IV infusion: Discontinue heparin infusion for 2-4 h and check partial thromboplastin (PTT) prior to block ... IV infusion: Discontinue heparin infusion for 2-4 h and check partial thromboplastin (PTT) prior to block ... Wait 2-4 h after last SC heparin dose or discontinuing IV heparin infusion; check PTT prior to removal ...
Ambulatory infusion pump - CADD-Legacy® PLUS pump. CISSS de la Montérégie-Centre16 February 2022 ...
The device pumps insulin continuously day and night. It can also deliver insulin more rapidly (bolus) before ... An insulin pump is a small device that delivers insulin through a small plastic tube (catheter). ... Need to operate pump, replace batteries, set doses, and so on. *Wearing the pump makes it obvious to others that you have ... An insulin pump is a small device that delivers insulin through a small plastic tube (catheter). The device pumps insulin ...
Load cells for infusion pumps. Infusion pumps are used for the intravenous administration of infusions. Special strain gauge- ... pumps, lifters, CPR devices, and hand and finger dynamometers. As medical-technical progress opens up new paths regarding ...
Tag Archives: Synchromed Pump. * Medtronic Synchromed II Lawsuit Over Infusion Pump Malfunction Survives Motion to Dismiss. ... Medtronic SynchroMed II Infusion Pump Recall Issued Over Stalled Motor Risk. December 17, 2019 By: Russell Maas ... Medtronic SynchroMed Infusion Pump Problems Result in Consent Decree With FDA. April 28, 2015 By: Irvin Jackson ... Federal Judge Refuses To Dismiss Medtronic SynchroMed II Infusion Pump Lawsuit. November 05, 2020 By: Irvin Jackson ...
Do not use insulin detemir in an infusion pump.. Do not change brands or types of insulin without directions on how to do so ...
... www.zdnet.com/article/palo-alto-more-than-100000-infusion-pumps-vulnerable-to-2-vulnerabilities/. ... Palo Alto: More than 100,000 infusion pumps vulnerable to 2 vulnerabilities. 03/08/2022. https:// ...
g. Medical infusion pumps h. Any implanted device that is incompatible with MRI. 2. Unsatisfactory performance status as judged ...
... pump delivery of PTH 1-34 provides more physiologic calcium homeostasis and bone turnover in children with severe congenital ... Subcutaneous Infusion of rhPTH1-34 During Pregnancy and Nursing in a Woman With Autosomal Dominant Hypoparathyroidism 1. ... Results: PTH 1-34 delivered via pump produced near normalization of mean serum calcium (2.02 ± 0.05 [pump] vs 1.88 ± 0.03 [ ... Effects of pump versus twice-daily injection delivery of synthetic parathyroid hormone 1-34 in children with severe congenital ...
Massive air emboli from intravenous infusion pump: etiology and prevention. Am J Surg. 1979 Feb. 137(2):274-5. [QxMD MEDLINE ...
  • Toxicities and complications were prospectively analyzed in patients with liver metastases receiving hepatic intra-arterial (IA) and systemic intravenous (IV) floxuridine (FUDR) with the Infusaid (Intermedics-Infusaid Corp., Norwood, MA) implantable pump. (nih.gov)
  • Who are the Major Players in Medical Intravenous Infusion Pump Market? (rnrmarketresearch.com)
  • Use intravenous (IV) infusion if subcutaneous infusion is not tolerated. (nih.gov)
  • Chronic intravenous infusions delivered using an external infusion pump with an indwelling central venous catheter are associated with the risk of blood stream infections (BSIs) and sepsis, which may be fatal. (nih.gov)
  • Infusion pumps are used for the intravenous administration of infusions. (medicaldevice-network.com)
  • used routinely in hospitals to maintain a patent intravenous line, to administer antineoplastic agents and other drugs in thromboembolism, heart disease, diabetes mellitus ( INSULIN INFUSION SYSTEMS is also available), and other disorders. (nih.gov)
  • Usability of volumetric infusion pumps in pediatric intensive care. (bvsalud.org)
  • 10. Technical complications and durability of hepatic artery infusion pumps for unresectable colorectal liver metastases: an institutional experience of 544 consecutive cases. (nih.gov)
  • Promising Quality In Our LINSZ-10 Series AIO Pump, LINZ-9 Series Micro Syringe Pump, LINZ-8 Series Micro Syringe Pump, etc. (leienmedical.com)
  • Shanghai Leien Medical Equipment Co., Ltd. is a hi-tech company in Shanghai, China, indulged in manufacturing LINZ-8B Double Channel Micro Syringe Pump, Triple Channel LINZ-9C Micro Syringe Pump, LINSZ-10C AIO Pump (I Infusion And II Syringe), etc. (leienmedical.com)
  • Our unit of manufacturing Triple Channel LINZ-9C Micro Syringe Pump, LINZ-8B Double Channel Micro Syringe Pump, LINSZ-10C AIO Pump (I Infusion And II Syringe), etc., spreads across 1500 square meters of land. (leienmedical.com)
  • For example, delivery of isocyanates was accomplished by interfacing a KD Scientific 200 Two-Syringe Infusion Pump with an EZSTARTER airbrush with an atomizing nozzle from PAASCHE. (cdc.gov)
  • 9. [Long-term regional chemotherapy for colorectal liver metastasis: significance of hepatic arterial anatomy in the surgical placement of the implantable infusion device]. (nih.gov)
  • 7. Multidetector CT arteriography with volumetric three-dimensional rendering to evaluate patients with metastatic colorectal disease for placement of a floxuridine infusion pump. (nih.gov)
  • Since then, the availability of lightweight ambulatory pumps has made infusion therapy possible in alternative settings outside the hospital, including in the home. (ismp.org)
  • A new market research study suggests that the use of ambulatory pumps is commonplace and will continue to grow at an annual rate of about 9% over the next 5 years. (ismp.org)
  • Ongoing technology developments and newer applications of ambulatory pumps in the home are further driving an increase in their use. (ismp.org)
  • Today, ambulatory pumps are being used to deliver various medications ( Table 1 ) to treat a wide array of diseases and conditions, from diabetes to chronic pain. (ismp.org)
  • Examples of medications/medication classes and solutions commonly administered at home via ambulatory pumps. (ismp.org)
  • The ambulatory pump marketplace is diverse, so the devices rarely have standard components. (ismp.org)
  • Often, healthcare providers are not familiar with all the ambulatory pumps in use, and most patients who use these devices are ill informed, leading to serious errors-the most dangerous of which is overinfusion. (ismp.org)
  • For example, just recently in our June 18, 2015 newsletter, we described numerous overinfusions of fluorouracil caused by misprogramming a CADD ambulatory infusion pump and misusing a rate-specific elastomeric EASYPUMP . (ismp.org)
  • So, what happens in your hospital when a patient using an ambulatory pump to deliver a medication or solution is admitted to the ED or hospital? (ismp.org)
  • Turning off the ambulatory pump without understanding its purpose and contents could lead to serious, even fatal, events. (ismp.org)
  • The ambulatory infusion pump is provided with a preloaded spring having a fixed spring constant. (justia.com)
  • This invention relates to an ambulatory infusion pump. (justia.com)
  • More particularly, this invention relates to an ambulatory infusion pump for dispensing fluids such as medications. (justia.com)
  • 1. Saphenous vein graft conduits for insertion of hepatic arterial infusion pumps in patients with abnormal hepatic arterial anatomy. (nih.gov)
  • 4. Laparoscopic placement of hepatic artery infusion pumps: technical considerations and early results. (nih.gov)
  • 8. Hepatic artery infusion of chemotherapy as a treatment for hepatic metastases from colorectal cancer. (nih.gov)
  • 11. Extrahepatic biliary stenoses after hepatic arterial infusion (HAI) of floxuridine (FUdR) for liver metastases from colorectal cancer. (nih.gov)
  • 13. Adjuvant hepatic arterial infusion after curative resection of colorectal liver metastases using removable intra-arterial catheters with shape-memory alloy. (nih.gov)
  • 14. Laparoscopic radiofrequency ablation and hepatic artery infusion pump placement in the evolving treatment of colorectal hepatic metastases. (nih.gov)
  • 16. Hepatic arterial infusion chemotherapy through a port-catheter system as preoperative initial therapy in patients with advanced liver dysfunction due to synchronous and unresectable liver metastases from colorectal cancer. (nih.gov)
  • The global infusion pump market size is expected to reach USD 24.6 Billion by 2030, with a CAGR of 8.3% from 2022 to 2030. (marketstatsnews.com)
  • 150+ Pages Report] As per the latest Research and survey report issued by Precedence Research, the global infusion pump market was valued at around USD 12 billion in 2021 and is expected to register revenues worth USD 24.6 billion by the end of 2030 , growing at an exceptional CAGR of approximately 8.3% between 2022 and 2030. (marketstatsnews.com)
  • A recent study by Precedence Research on the infusion pump market offers a forecast for 2022 and 2030. (marketstatsnews.com)
  • In our November 20, 2014 newsletter, we published an event in which both a patient and clinicians in the ED mistakenly believed an elastomeric DOSI-FUSER pump had malfunctioned and delivered an overinfusion of fluorouracil when it had not, leading to the omission of a large portion of the prescribed chemotherapy after the infusion was disconnected prematurely. (ismp.org)
  • 6. [Complication due to arterial infusion chemotherapy for liver metastasis from colorectal cancer]. (nih.gov)
  • An infusion pump is an instrument that can accurately control the number of infusion drops or infusion flow rate to ensure that a drug can be evenly distributed, and the amount of the drug can accurately and safely enter a patient's body. (renesas.com)
  • 5 For example, in a 2014 consensus statement, the American Association of Clinical Endocrinologists and the American College of Endocrinology encourage hospitalized patients and their admitting physicians to not discontinue an insulin pump, but rather to consult the specialist responsible for the patient's insulin pump management if the patient cannot manage his or her own pump. (ismp.org)
  • Most pumps have a 'bolus wizard' to help calculate the bolus dose based on your blood glucose level and the meal (grams of carbohydrate) you are eating. (medlineplus.gov)
  • You can program the pump to deliver the bolus doses in different patterns. (medlineplus.gov)
  • To analyze the usability of two infusion pump models in a Pediatric Intensive Care Unit . (bvsalud.org)
  • 2. Complete coverage of all the segments in the infusion therapy market to analyze the trends, developments in the global market and forecast of market size up to 2026. (globenewswire.com)
  • Taking care of ICU patients requires a lot of special skills on top of dedication and meticulous attention to detail," she said, mentioning among them central line insertion, intubation, and operating machines like infusion pumps and ventilators. (who.int)
  • Continuous subcutaneous infusion is the preferred mode. (nih.gov)
  • Children and young adults aged 7-20 years with congenital hypoparathyroidism (N = 12) were randomized to receive PTH 1-34, delivered either by twice-daily subcutaneous injection or insulin pump for 13 weeks, followed by crossover to the opposite delivery method. (nih.gov)
  • There are different types of insulin pumps. (nih.gov)
  • As with any medication delivery system, patient safety can be jeopardized if the devices are mishandled when filling, programming, attaching, and monitoring the pumps. (ismp.org)
  • Data analyzed from the Armis Asset Intelligence and Security Platform , which tracks over three billion assets, found nurse call systems to be the riskiest* IoMT device, followed by infusion pumps and medication dispensing systems. (businesswire.com)
  • To compare the response with synthetic human parathyroid hormone (PTH) 1-34 delivered by twice-daily injection vs insulin pump in children with severe congenital hypoparathyroidism due to calcium receptor mutation or autoimmune polyglandular syndrome type 1. (nih.gov)
  • People with type 1 diabetes control their blood glucose level by checking it and taking insulin, either by injection or through an insulin infusion pump , several times a day. (nih.gov)
  • The report predicts the global infusion therapy market to grow with a CAGR of 4.1% over the forecast period from 2020-2026. (globenewswire.com)
  • A Medtronic SynchroMed II lawsuit claims the drug infusion pump repeatedly overdosed a woman when she had the drug reservoir refilled. (aboutlawsuits.com)
  • Thousands of Medtronic SynchroMed II infusion pumps are being recalled due to the risk of the motor stalling. (aboutlawsuits.com)
  • Medtronic says a new system to be used with its SynchroMed infusion pump will help wean patients off of addictive opoid pain killers. (aboutlawsuits.com)
  • Some older Medtronic SynchroMed II infusion pumps may have a more than 3% chance of battery failure, which could necessitate revision surgery, the company warns. (aboutlawsuits.com)
  • Medtronic has issued a warning letter indicating that its SynchroMed II infusion pump has been linked to drug overdoses that have left at least two dead. (aboutlawsuits.com)
  • Problems with Medtronic Synchromed II Infusion Pump cause a Pennsylvania man to receive an over delivery of pain medications, resulting in hospitalization and permanent injuries. (aboutlawsuits.com)
  • Medtronic and the FDA have entered into a consent decree over manufacturing violations involving the Synchromed II Infusion Pump. (aboutlawsuits.com)
  • The report has engulfed a chapter on the global infusion pump market's competitive landscape, which provides detailed analysis and insights on companies offering infusion pump. (marketstatsnews.com)
  • Porter's five forces model in the report provides insights into the competitive rivalry, supplier and buyer positions in the market and opportunities for the new entrants in the global infusion therapy market over the period of 2018 to 2026. (globenewswire.com)
  • Hypoglycemia is a well-recognized complication of intensive control of diabetes (3), but further information is necessary before conclusions can be drawn as to whether hypoglycemia was the cause of death in a greater-than-expected number of patients using insulin infusion devices. (cdc.gov)
  • When patients with insulin pumps are evaluated in the ED or admitted to the hospital, they typically have more knowledge and expertise with using the pump for insulin delivery than the medical professionals who are handling their care. (ismp.org)
  • A separate wireless device programs insulin delivery from the pump. (medlineplus.gov)
  • This allows you (or in some cases the pump) to stop insulin delivery if blood glucose is becoming too low. (medlineplus.gov)
  • patients used pumps from more than 1 manufacturer. (cdc.gov)
  • Further investigation of the cases reported here is warranted, and surveillance of deaths among patients using insulin infusion pumps should be established. (cdc.gov)
  • Editorial Note: No data on morbidity or mortality are currently available from a group of diabetics under intensive control and not using infusion pumps, i.e., comparable to patients using infusion pumps. (cdc.gov)
  • Before the 1980s, patients had to be hospitalized to receive various types of infusion therapies to treat diseases unresponsive to oral medications. (ismp.org)
  • Insulin pumps provide another example of a unique challenge to clinicians when patients with these devices present for treatment. (ismp.org)
  • In 2007, about 374,000 patients with type 1 diabetes were using insulin pumps. (ismp.org)
  • 2 Today, more than half a million patients with type 1 and type 2 diabetes are using insulin pumps. (ismp.org)
  • The insulin infusion pump will deliver small doses of insulin throughout the day when blood glucose levels are not in your target range. (nih.gov)
  • In the year 2016, we launched AIO Pump, which is one of the milestones in the history of Infusion Pumps. (leienmedical.com)
  • The study also provides the dynamics that are responsible for influencing the future status of the infusion pump market over the forecast period. (marketstatsnews.com)
  • Traditional pumps include an insulin reservoir (cartridge) and a catheter. (medlineplus.gov)
  • Patch pumps are worn directly on the body with the reservoir and tubes inside a small case. (medlineplus.gov)
  • Pumps come with features such as waterproofing, touchscreen, and alerts for dosage time and insulin reservoir capacity. (medlineplus.gov)
  • Alarm problems and infusion pump medications errors are on the top of the list of hospital problems that need to be addressed. (klinespecter.com)
  • The Plum A+ Infusion Systems are a multi-purpose family of devices that provides precise delivery of multiple therapies across the general spectrum of clinical care. (fda.gov)
  • The Plum A+ family infusion pumps are self-contained, microprocessor based infusion devices. (fda.gov)
  • Insulin infusion pumps are open loop devices that administer insulin subcutaneously at a constant low level and deliver added amounts before meals. (cdc.gov)
  • Infusion devices have also been known, such as described in U.S. Pat. (justia.com)
  • An insulin pump is a small device that delivers insulin through a small plastic tube (catheter). (medlineplus.gov)
  • Tubing connects the catheter to a pump that has a digital display. (medlineplus.gov)
  • Insulin flows from the pump through a plastic tube that connects to a smaller tube, called a catheter , which has a needle that is inserted under the skin and stays in place for several days. (nih.gov)
  • Another type of pump attaches directly to the skin with an adhesive pad and gives insulin through a catheter inserted under the skin. (nih.gov)
  • While none of the deaths could be attributed to the infusion pumps, some deaths may have been due to the intensive glycemia control used as a therapeutic goal. (cdc.gov)
  • Some pumps can connect or communicate with a glucose sensor to monitor blood glucose levels (continuous glucose monitor or CGM). (medlineplus.gov)
  • Many pumps now communicate wirelessly with continuous glucose monitors (CGMs). (medlineplus.gov)
  • An artificial pancreas system uses a continuous glucose monitor, an insulin pump, and a program stored on the pump or a smartphone (top). (nih.gov)
  • The report on the global infusion therapy market provides qualitative and quantitative analysis for the period from 2018 to 2026. (globenewswire.com)
  • This solution is an intelligent infusion device. (renesas.com)
  • The device pumps insulin continuously day and night. (medlineplus.gov)
  • Insulin pumps can help some people with diabetes have more control in managing blood glucose. (medlineplus.gov)
  • Your diabetes team (and the pump manufacturer) will help you learn everything you need to know to use the pump successfully. (medlineplus.gov)
  • The study on infusion therapy market covers the analysis of the leading geographies such as North America, Europe, Asia-Pacific, and RoW for the period of 2018 to 2026. (globenewswire.com)
  • The report on infusion therapy market is a comprehensive study and presentation of drivers, restraints, opportunities, demand factors, market size, forecasts, and trends in the global infusion therapy market over the period of 2018 to 2026. (globenewswire.com)
  • The global infusion therapy market is segmented on the basis of product type, application, and end user. (globenewswire.com)
  • 1. Comprehensive analysis of the global as well as regional markets of the infusion therapy market. (globenewswire.com)
  • 3. Comprehensive analysis of the companies operating in the global infusion therapy market. (globenewswire.com)
  • This Volumetric Infusion Pump has visual and audio alarm function and safety function. (halomedicals.com)
  • There are approximately 5 million diabetics in the United States, of whom 5%-15% are Type I. Approximately 4,000 pumps are currently in use in the United States, and the number is growing rapidly (1). (cdc.gov)
  • One type of pump is worn outside the body on a belt or in a pocket or pouch. (nih.gov)
  • It is another object of the invention to be able to change the flow rate of an infusion pump. (justia.com)
  • This report explicates on vital dynamics such as the drivers, restraints, and opportunities for key market players, along with key stakeholders as well as emerging players associated with the manufacturing of infusion pump. (marketstatsnews.com)
  • Thus, although 4,000 pumps are currently estimated to be in use in the United States, the number of patient years of insulin pump use may be substantially less than the number of pumps might indicate. (cdc.gov)
  • It is another object of the invention to provide an infusion pump which can be worn by a patient and used in a reliable manner. (justia.com)
  • The study analyzes crucial trends that are currently determining the growth of the infusion pump market. (marketstatsnews.com)
  • A detailed assessment of the infusion pump market value chain analysis, business execution, and supply chain analysis across regional markets has been covered in the report. (marketstatsnews.com)
  • A list of prominent companies operating in the infusion pump market along with their product portfolio enhances the reliability of this comprehensive research study. (marketstatsnews.com)
  • It is another object of the invention to provide an infusion pump which is able to maintain a substantially uniform rate of discharge of fluid over time. (justia.com)
  • Dedicated Mindray infusion sets be used delivering high ac. (acailangola.com)
  • Most insulin pumps are about the size of a small mobile phone, but models keep getting smaller. (medlineplus.gov)
  • The insulin pump can be worn on a belt, stored in a pocket, or attached directly to the skin (bottom). (nih.gov)
  • The biasing force of the spring and the stroke of the piston are coordinated so as to maintain a pressure on the fluid being dispensed from the pump housing which decreases at a slow rate and within a range of about 15% of the referenced pressure. (justia.com)
  • Further, infusion pumps have been known which employ constant force springs to impose a driving force on a piston in order to expel fluid from a housing. (justia.com)
  • Briefly, the invention provides an infusion pump which is able to deliver fluid over a prolonged period of time at a pressure which changes by less than about plus or minus 15% of the referenced pressure over the total time period. (justia.com)
  • To this end, the infusion pump is comprised of a tubular housing for a fluid, a piston slidably mounted in the housing and a spring within the housing for imposing a biasing force on the piston which decreases during movement of the piston from a filled position to an empty position. (justia.com)
  • Talk to your health care provider about which pump is right for you. (medlineplus.gov)
  • This One-channel Volumetric Infusion Pump is design ergonomically and user friendly. (halomedicals.com)