Inability to reproduce after a specified period of unprotected intercourse. Reproductive sterility is permanent infertility.
The inability of the male to effect FERTILIZATION of an OVUM after a specified period of unprotected intercourse. Male sterility is permanent infertility.
Diminished or absent ability of a female to achieve conception.
Clinical and laboratory techniques used to enhance fertility in humans and animals.
Diseases involving the FALLOPIAN TUBES including neoplasms (FALLOPIAN TUBE NEOPLASMS); SALPINGITIS; tubo-ovarian abscess; and blockage.
Mature male germ cells derived from SPERMATIDS. As spermatids move toward the lumen of the SEMINIFEROUS TUBULES, they undergo extensive structural changes including the loss of cytoplasm, condensation of CHROMATIN into the SPERM HEAD, formation of the ACROSOME cap, the SPERM MIDPIECE and the SPERM TAIL that provides motility.
A condition of having no sperm present in the ejaculate (SEMEN).
The capacity to conceive or to induce conception. It may refer to either the male or female.
An assisted reproductive technique that includes the direct handling and manipulation of oocytes and sperm to achieve fertilization in vitro.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
A condition of suboptimal concentration of SPERMATOZOA in the ejaculated SEMEN to ensure successful FERTILIZATION of an OVUM. In humans, oligospermia is defined as a sperm count below 20 million per milliliter semen.
The process of germ cell development in the male from the primordial germ cells, through SPERMATOGONIA; SPERMATOCYTES; SPERMATIDS; to the mature haploid SPERMATOZOA.
A count of SPERM in the ejaculum, expressed as number per milliliter.
Movement characteristics of SPERMATOZOA in a fresh specimen. It is measured as the percentage of sperms that are moving, and as the percentage of sperms with productive flagellar motion such as rapid, linear, and forward progression.
A condition in which functional endometrial tissue is present outside the UTERUS. It is often confined to the PELVIS involving the OVARY, the ligaments, cul-de-sac, and the uterovesical peritoneum.
Radiography of the uterus and fallopian tubes after the injection of a contrast medium.
A condition characterized by the dilated tortuous veins of the SPERMATIC CORD with a marked left-sided predominance. Adverse effect on male fertility occurs when varicocele leads to an increased scrotal (and testicular) temperature and reduced testicular volume.
The thick, yellowish-white, viscid fluid secretion of male reproductive organs discharged upon ejaculation. In addition to reproductive organ secretions, it contains SPERMATOZOA and their nutrient plasma.
The quality of SEMEN, an indicator of male fertility, can be determined by semen volume, pH, sperm concentration (SPERM COUNT), total sperm number, sperm viability, sperm vigor (SPERM MOTILITY), normal sperm morphology, ACROSOME integrity, and the concentration of WHITE BLOOD CELLS.
Methods pertaining to the generation of new individuals, including techniques used in selective BREEDING, cloning (CLONING, ORGANISM), and assisted reproduction (REPRODUCTIVE TECHNIQUES, ASSISTED).
The ratio of the number of conceptions (CONCEPTION) including LIVE BIRTH; STILLBIRTH; and fetal losses, to the mean number of females of reproductive age in a population during a set time period.
A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue. Note that ENCLOMIPHENE and ZUCLOMIPHENE are the (E) and (Z) isomers of Clomiphene respectively.
The male gonad containing two functional parts: the SEMINIFEROUS TUBULES for the production and transport of male germ cells (SPERMATOGENESIS) and the interstitial compartment containing LEYDIG CELLS that produce ANDROGENS.
Suspension or cessation of OVULATION in animals or humans with follicle-containing ovaries (OVARIAN FOLLICLE). Depending on the etiology, OVULATION may be induced with appropriate therapy.
A condition in which the percentage of progressively motile sperm is abnormally low. In men, it is defined as
An assisted fertilization technique consisting of the microinjection of a single viable sperm into an extracted ovum. It is used principally to overcome low sperm count, low sperm motility, inability of sperm to penetrate the egg, or other conditions related to male infertility (INFERTILITY, MALE).
Techniques for the artifical induction of ovulation, the rupture of the follicle and release of the ovum.
A medical-surgical specialty concerned with the morphology, physiology, biochemistry, and pathology of reproduction in man and other animals, and on the biological, medical, and veterinary problems of fertility and lactation. It includes ovulation induction, diagnosis of infertility and recurrent pregnancy loss, and assisted reproductive technologies such as embryo transfer, in vitro fertilization, and intrafallopian transfer of zygotes. (From Infertility and Reproductive Medicine Clinics of North America, Foreword 1990; Journal of Reproduction and Fertility, Notice to Contributors, Jan 1979)
The human male sex chromosome, being the differential sex chromosome carried by half the male gametes and none of the female gametes in humans.
Compounds which increase the capacity to conceive in females.
Artificial introduction of SEMEN or SPERMATOZOA into the VAGINA to facilitate FERTILIZATION.
Results of conception and ensuing pregnancy, including LIVE BIRTH; STILLBIRTH; SPONTANEOUS ABORTION; INDUCED ABORTION. The outcome may follow natural or artificial insemination or any of the various ASSISTED REPRODUCTIVE TECHNIQUES, such as EMBRYO TRANSFER or FERTILIZATION IN VITRO.
The transfer of mammalian embryos from an in vivo or in vitro environment to a suitable host to improve pregnancy or gestational outcome in human or animal. In human fertility treatment programs, preimplantation embryos ranging from the 4-cell stage to the blastocyst stage are transferred to the uterine cavity between 3-5 days after FERTILIZATION IN VITRO.
Human artificial insemination in which the husband's semen is used.
A pair of highly specialized muscular canals extending from the UTERUS to its corresponding OVARY. They provide the means for OVUM collection, and the site for the final maturation of gametes and FERTILIZATION. The fallopian tube consists of an interstitium, an isthmus, an ampulla, an infundibulum, and fimbriae. Its wall consists of three histologic layers: serous, muscular, and an internal mucosal layer lined with both ciliated and secretory cells.
The reproductive organ (GONADS) in female animals. In vertebrates, the ovary contains two functional parts: the OVARIAN FOLLICLE for the production of female germ cells (OOGENESIS); and the endocrine cells (GRANULOSA CELLS; THECA CELLS; and LUTEAL CELLS) for the production of ESTROGENS and PROGESTERONE.
Abnormal number or structure of the SEX CHROMOSOMES. Some sex chromosome aberrations are associated with SEX CHROMOSOME DISORDERS and SEX CHROMOSOME DISORDERS OF SEX DEVELOPMENT.
Inflammation of a TESTIS. It has many features of EPIDIDYMITIS, such as swollen SCROTUM; PAIN; PYURIA; and FEVER. It is usually related to infections in the URINARY TRACT, which likely spread to the EPIDIDYMIS and then the TESTIS through either the VAS DEFERENS or the lymphatics of the SPERMATIC CORD.
The fusion of a spermatozoon (SPERMATOZOA) with an OVUM thus resulting in the formation of a ZYGOTE.
Pathological processes involving any part of the UTERUS.
Endometrial implantation of EMBRYO, MAMMALIAN at the BLASTOCYST stage.
A spectrum of inflammation involving the female upper genital tract and the supporting tissues. It is usually caused by an ascending infection of organisms from the endocervix. Infection may be confined to the uterus (ENDOMETRITIS), the FALLOPIAN TUBES; (SALPINGITIS); the ovaries (OOPHORITIS), the supporting ligaments (PARAMETRITIS), or may involve several of the above uterine appendages. Such inflammation can lead to functional impairment and infertility.
Proteins found in SEMEN. Major seminal plasma proteins are secretory proteins from the male sex accessory glands, such as the SEMINAL VESICLES and the PROSTATE. They include the seminal vesicle-specific antigen, an ejaculate clotting protein; and the PROSTATE-SPECIFIC ANTIGEN, a protease and an esterase.
Congenital conditions of atypical sexual development associated with abnormal sex chromosome constitutions including MONOSOMY; TRISOMY; and MOSAICISM.
The male sex chromosome, being the differential sex chromosome carried by half the male gametes and none of the female gametes in humans and in some other male-heterogametic species in which the homologue of the X chromosome has been retained.
Methods for assessing the patency of the fallopian tubes.
A variation from the normal set of chromosomes characteristic of a species.
Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections.
A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. Polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. The term, polycystic ovary, is misleading.
A scientific or medical discipline concerning the study of male reproductive biology, diseases of the male genital organs, and male infertility. Major areas of interest include ENDOCRINOLOGY; SPERMATOGENESIS; semen analysis; FERTILIZATION; CONTRACEPTION; and CRYOPRESERVATION.
Pathological processes of the TESTIS.
The mucous membrane lining of the uterine cavity that is hormonally responsive during the MENSTRUAL CYCLE and PREGNANCY. The endometrium undergoes cyclic changes that characterize MENSTRUATION. After successful FERTILIZATION, it serves to sustain the developing embryo.
A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Follicle-stimulating hormone stimulates GAMETOGENESIS and the supporting cells such as the ovarian GRANULOSA CELLS, the testicular SERTOLI CELLS, and LEYDIG CELLS. FSH consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity.
Infections with bacteria of the genus CHLAMYDIA.
Drugs used to increase fertility or to treat infertility.
Pathological processes of the OVARY.
The convoluted cordlike structure attached to the posterior of the TESTIS. Epididymis consists of the head (caput), the body (corpus), and the tail (cauda). A network of ducts leaving the testis joins into a common epididymal tubule proper which provides the transport, storage, and maturation of SPERMATOZOA.
Expulsion of the product of FERTILIZATION before completing the term of GESTATION and without deliberate interference.
The discharge of an OVUM from a rupturing follicle in the OVARY.
Type species of CHLAMYDIA causing a variety of ocular and urogenital diseases.
Female germ cells derived from OOGONIA and termed OOCYTES when they enter MEIOSIS. The primary oocytes begin meiosis but are arrested at the diplotene state until OVULATION at PUBERTY to give rise to haploid secondary oocytes or ova (OVUM).
The condition of carrying two or more FETUSES simultaneously.
Three or more consecutive spontaneous abortions.
The hollow thick-walled muscular organ in the female PELVIS. It consists of the fundus (the body) which is the site of EMBRYO IMPLANTATION and FETAL DEVELOPMENT. Beyond the isthmus at the perineal end of fundus, is CERVIX UTERI (the neck) opening into VAGINA. Beyond the isthmi at the upper abdominal end of fundus, are the FALLOPIAN TUBES.
MYCOBACTERIUM infections of the female reproductive tract (GENITALIA, FEMALE).
Centers for acquiring and storing semen.
Endoscopic examination, therapy or surgery of the interior of the uterus.
The number of births in a given population per year or other unit of time.
Contraceptive methods based on immunological processes and techniques, such as the use of CONTRACEPTIVE VACCINES.
Pathological processes consisting of the union of the opposing surfaces of a wound.
Supporting cells projecting inward from the basement membrane of SEMINIFEROUS TUBULES. They surround and nourish the developing male germ cells and secrete ANDROGEN-BINDING PROTEIN and hormones such as ANTI-MULLERIAN HORMONE. The tight junctions of Sertoli cells with the SPERMATOGONIA and SPERMATOCYTES provide a BLOOD-TESTIS BARRIER.
Hormones that stimulate gonadal functions such as GAMETOGENESIS and sex steroid hormone production in the OVARY and the TESTIS. Major gonadotropins are glycoproteins produced primarily by the adenohypophysis (GONADOTROPINS, PITUITARY) and the placenta (CHORIONIC GONADOTROPIN). In some species, pituitary PROLACTIN and PLACENTAL LACTOGEN exert some luteotropic activities.
The state of estrangement individuals feel in cultural settings that they view as foreign, unpredictable, or unacceptable.
The event that a FETUS is born alive with heartbeats or RESPIRATION regardless of GESTATIONAL AGE. Such liveborn is called a newborn infant (INFANT, NEWBORN).
Preservation of cells, tissues, organs, or embryos by freezing. In histological preparations, cryopreservation or cryofixation is used to maintain the existing form, structure, and chemical composition of all the constituent elements of the specimens.
Human behavior or decision related to REPRODUCTION.
A form of male HYPOGONADISM, characterized by the presence of an extra X CHROMOSOME, small TESTES, seminiferous tubule dysgenesis, elevated levels of GONADOTROPINS, low serum TESTOSTERONE, underdeveloped secondary sex characteristics, and male infertility (INFERTILITY, MALE). Patients tend to have long legs and a slim, tall stature. GYNECOMASTIA is present in many of the patients. The classic form has the karyotype 47,XXY. Several karyotype variants include 48,XXYY; 48,XXXY; 49,XXXXY, and mosaic patterns ( 46,XY/47,XXY; 47,XXY/48,XXXY, etc.).
The emission of SEMEN to the exterior, resulting from the contraction of muscles surrounding the male internal urogenital ducts.
Male germ cells derived from the haploid secondary SPERMATOCYTES. Without further division, spermatids undergo structural changes and give rise to SPERMATOZOA.
Surgical anastomosis or fistulization of the spermatic ducts to restore fertility in a previously vasectomized male.
The convoluted tubules in the TESTIS where sperm are produced (SPERMATOGENESIS) and conveyed to the RETE TESTIS. Spermatogenic tubules are composed of developing germ cells and the supporting SERTOLI CELLS.
Interactive processes between the oocyte (OVUM) and the sperm (SPERMATOZOA) including sperm adhesion, ACROSOME REACTION, sperm penetration of the ZONA PELLUCIDA, and events leading to FERTILIZATION.
Condition resulting from deficient gonadal functions, such as GAMETOGENESIS and the production of GONADAL STEROID HORMONES. It is characterized by delay in GROWTH, germ cell maturation, and development of secondary sex characteristics. Hypogonadism can be due to a deficiency of GONADOTROPINS (hypogonadotropic hypogonadism) or due to primary gonadal failure (hypergonadotropic hypogonadism).
Variations of menstruation which may be indicative of disease.
A developmental defect in which a TESTIS or both TESTES failed to descend from high in the ABDOMEN to the bottom of the SCROTUM. Testicular descent is essential to normal SPERMATOGENESIS which requires temperature lower than the BODY TEMPERATURE. Cryptorchidism can be subclassified by the location of the maldescended testis.
Extracts of urine from menopausal women that contain high concentrations of pituitary gonadotropins, FOLLICLE STIMULATING HORMONE and LUTEINIZING HORMONE. Menotropins are used to treat infertility. The FSH:LH ratio and degree of purity vary in different preparations.
The posterior filiform portion of the spermatozoon (SPERMATOZOA) that provides sperm motility.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
A procedure in which a laparoscope (LAPAROSCOPES) is inserted through a small incision near the navel to examine the abdominal and pelvic organs in the PERITONEAL CAVITY. If appropriate, biopsy or surgery can be performed during laparoscopy.
Transfer of preovulatory oocytes from donor to a suitable host. Oocytes are collected, fertilized in vitro, and transferred to a host that can be human or animal.
Time interval, or number of non-contraceptive menstrual cycles that it takes for a couple to conceive.
The islands of the central and South Pacific, including Micronesia, Melanesia, Polynesia, and traditionally Australasia. (Random House Dictionary, 2d ed)
A type of male infertility in which no germ cells are visible in any of the biopsied SEMINIFEROUS TUBULES (type I) or in which germ cells are present in a minority of tubules (type II). Clinical features include AZOOSPERMIA, normal VIRILIZATION, and normal chromosomal complement.
Methods and procedures for the diagnosis of conditions related to pregnancy, labor, and the puerperium and of diseases of the female genitalia. It includes also demonstration of genital and pregnancy physiology.
Pathological processes of the OVARIES or the TESTES.
Health care services related to human REPRODUCTION and diseases of the reproductive system. Services are provided to both sexes and usually by physicians in the medical or the surgical specialties such as REPRODUCTIVE MEDICINE; ANDROLOGY; GYNECOLOGY; OBSTETRICS; and PERINATOLOGY.
Procedures to obtain viable OOCYTES from the host. Oocytes most often are collected by needle aspiration from OVARIAN FOLLICLES before OVULATION.
The social institution involving legal and/or religious sanction whereby individuals are joined together.
A major gonadotropin secreted by the human adenohypophysis (PITUITARY GLAND, ANTERIOR). Follicle-stimulating hormone stimulates GAMETOGENESIS and the supporting cells such as the ovarian GRANULOSA CELLS, the testicular SERTOLI CELLS, and the LEYDIG CELLS. FSH consists of two noncovalently linked subunits, alpha and beta. The alpha subunit is common in the three human pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity.
Mystical, religious, or spiritual practices performed for health benefit.
Human artificial insemination in which the semen used is that of a man other than the woman's husband.
A tough transparent membrane surrounding the OVUM. It is penetrated by the sperm during FERTILIZATION.
Inflammation of the uterine salpinx, the trumpet-shaped FALLOPIAN TUBES, usually caused by ascending infections of organisms from the lower reproductive tract. Salpingitis can lead to tubal scarring, hydrosalpinx, tubal occlusion, INFERTILITY, and ectopic pregnancy (PREGNANCY, ECTOPIC)
The deposit of SEMEN or SPERMATOZOA into the VAGINA to facilitate FERTILIZATION.
The total process by which organisms produce offspring. (Stedman, 25th ed)
A technique that came into use in the mid-1980's for assisted conception in infertile women with normal fallopian tubes. The protocol consists of hormonal stimulation of the ovaries, followed by laparoscopic follicular aspiration of oocytes, and then the transfer of sperm and oocytes by catheterization into the fallopian tubes.
Procedures to obtain viable sperm from the male reproductive tract, including the TESTES, the EPIDIDYMIS, or the VAS DEFERENS.
An OOCYTE-containing structure in the cortex of the OVARY. The oocyte is enclosed by a layer of GRANULOSA CELLS providing a nourishing microenvironment (FOLLICULAR FLUID). The number and size of follicles vary depending on the age and reproductive state of the female. The growing follicles are divided into five stages: primary, secondary, tertiary, Graafian, and atretic. Follicular growth and steroidogenesis depend on the presence of GONADOTROPINS.
A group of simple proteins that yield basic amino acids on hydrolysis and that occur combined with nucleic acid in the sperm of fish. Protamines contain very few kinds of amino acids. Protamine sulfate combines with heparin to form a stable inactive complex; it is used to neutralize the anticoagulant action of heparin in the treatment of heparin overdose. (From Merck Index, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p692)
Clinical conditions caused by an abnormal sex chromosome constitution (SEX CHROMOSOME ABERRATIONS), in which there is extra or missing sex chromosome material (either a whole chromosome or a chromosome segment).
A type of CELL NUCLEUS division, occurring during maturation of the GERM CELLS. Two successive cell nucleus divisions following a single chromosome duplication (S PHASE) result in daughter cells with half the number of CHROMOSOMES as the parent cells.
A common inhabitant of the vagina and cervix and a potential human pathogen, causing infections of the male and female reproductive tracts. It has also been associated with respiratory disease and pharyngitis. (From Dorland, 28th ed)
The maturing process of SPERMATOZOA after leaving the testicular SEMINIFEROUS TUBULES. Maturation in SPERM MOTILITY and FERTILITY takes place in the EPIDIDYMIS as the sperm migrate from caput epididymis to cauda epididymis.
A potentially life-threatening condition in which EMBRYO IMPLANTATION occurs outside the cavity of the UTERUS. Most ectopic pregnancies (>96%) occur in the FALLOPIAN TUBES, known as TUBAL PREGNANCY. They can be in other locations, such as UTERINE CERVIX; OVARY; and abdominal cavity (PREGNANCY, ABDOMINAL).
A republic in eastern Africa, south of UGANDA, east of DEMOCRATIC REPUBLIC OF THE CONGO, west of TANZANIA. Its capital is Kigali. It was formerly part of the Belgian trust territory of Ruanda-Urund.
The period from onset of one menstrual bleeding (MENSTRUATION) to the next in an ovulating woman or female primate. The menstrual cycle is regulated by endocrine interactions of the HYPOTHALAMUS; the PITUITARY GLAND; the ovaries; and the genital tract. The menstrual cycle is divided by OVULATION into two phases. Based on the endocrine status of the OVARY, there is a FOLLICULAR PHASE and a LUTEAL PHASE. Based on the response in the ENDOMETRIUM, the menstrual cycle is divided into a proliferative and a secretory phase.
Occurrence or induction of release of more ova than are normally released at the same time in a given species. The term applies to both animals and humans.
A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Luteinizing hormone regulates steroid production by the interstitial cells of the TESTIS and the OVARY. The preovulatory LUTEINIZING HORMONE surge in females induces OVULATION, and subsequent LUTEINIZATION of the follicle. LUTEINIZING HORMONE consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH and FSH), but the beta subunit is unique and confers its biological specificity.
Actual loss of portion of a chromosome.
Voluntary acceptance of a child of other parents to be as one's own child, usually with legal confirmation.
Pathological processes involving the female reproductive tract (GENITALIA, FEMALE).
Paired ducts in the human male through which semen is ejaculated into the urethra.
The anterior portion of the spermatozoon (SPERMATOZOA) that contains mainly the nucleus with highly compact CHROMATIN material.
A method of providing future reproductive opportunities before a medical treatment with known risk of loss of fertility. Typically reproductive organs or tissues (e.g., sperm, egg, embryos and ovarian or testicular tissues) are cryopreserved for future use before the medical treatment (e.g., chemotherapy, radiation) begins.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Women who allow themselves to be impregnated with the understanding that the offspring are to be given over to the parents who have commissioned the surrogate.
Surgical removal of the ductus deferens, or a portion of it. It is done in association with prostatectomy, or to induce infertility. (Dorland, 28th ed)
Euploid male germ cells of an early stage of SPERMATOGENESIS, derived from prespermatogonia. With the onset of puberty, spermatogonia at the basement membrane of the seminiferous tubule proliferate by mitotic then meiotic divisions and give rise to the haploid SPERMATOCYTES.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
A benign neoplasm of muscular tissue. (Stedman, 25th ed)
The number of offspring a female has borne. It is contrasted with GRAVIDITY, which refers to the number of pregnancies, regardless of outcome.
Chemical substances or agents with contraceptive activity in males. Use for male contraceptive agents in general or for which there is no specific heading.
The cap-like structure covering the anterior portion of SPERM HEAD. Acrosome, derived from LYSOSOMES, is a membrane-bound organelle that contains the required hydrolytic and proteolytic enzymes necessary for sperm penetration of the egg in FERTILIZATION.
Pathological processes involving the male reproductive tract (GENITALIA, MALE).
Infections of the genital tract in females or males. They can be caused by endogenous, iatrogenic, or sexually transmitted organisms.
The reproductive cells in multicellular organisms at various stages during GAMETOGENESIS.
Prevention of CONCEPTION by blocking fertility temporarily, or permanently (STERILIZATION, REPRODUCTIVE). Common means of reversible contraception include NATURAL FAMILY PLANNING METHODS; CONTRACEPTIVE AGENTS; or CONTRACEPTIVE DEVICES.
A benign tumor derived from smooth muscle tissue, also known as a fibroid tumor. They rarely occur outside of the UTERUS and the GASTROINTESTINAL TRACT but can occur in the SKIN and SUBCUTANEOUS TISSUE, probably arising from the smooth muscle of small blood vessels in these tissues.
Absence of menstruation.
Male germ cells derived from SPERMATOGONIA. The euploid primary spermatocytes undergo MEIOSIS and give rise to the haploid secondary spermatocytes which in turn give rise to SPERMATIDS.
Abnormally infrequent menstruation.
Tumors or cancer of the UTERUS.
Abnormal number or structure of chromosomes. Chromosome aberrations may result in CHROMOSOME DISORDERS.
Tumors or cancer of the TESTIS. Germ cell tumors (GERMINOMA) of the testis constitute 95% of all testicular neoplasms.
The geographical area of Africa comprising CAMEROON; CENTRAL AFRICAN REPUBLIC; CHAD; CONGO; EQUATORIAL GUINEA; GABON; and DEMOCRATIC REPUBLIC OF THE CONGO.
The period in the MENSTRUAL CYCLE that follows OVULATION, characterized by the development of CORPUS LUTEUM, increase in PROGESTERONE production by the OVARY and secretion by the glandular epithelium of the ENDOMETRIUM. The luteal phase begins with ovulation and ends with the onset of MENSTRUATION.
A sac or recess formed by a fold of the peritoneum.
A decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE. GnRH is produced by neurons in the septum PREOPTIC AREA of the HYPOTHALAMUS and released into the pituitary portal blood, leading to stimulation of GONADOTROPHS in the ANTERIOR PITUITARY GLAND.
The age of the mother in PREGNANCY.
A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).
Surgery performed on the male genitalia.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Inflammation of the EPIDIDYMIS. Its clinical features include enlarged epididymis, a swollen SCROTUM; PAIN; PYURIA; and FEVER. It is usually related to infections in the URINARY TRACT, which likely spread to the EPIDIDYMIS through either the VAS DEFERENS or the lymphatics of the SPERMATIC CORD.
The process by which semen is kept viable outside of the organism from which it was derived (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism).
The genital canal in the female, extending from the UTERUS to the VULVA. (Stedman, 25th ed)
The injection of very small amounts of fluid, often with the aid of a microscope and microsyringes.
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
A species of gram-negative bacteria originally isolated from urethral specimens of patients with non-gonoccocal URETHRITIS. In primates it exists in parasitic association with ciliated EPITHELIAL CELLS in the genital and respiratory tracts.
Personal care items for women.
An autosomal recessive disorder characterized by a triad of DEXTROCARDIA; INFERTILITY; and SINUSITIS. The syndrome is caused by mutations of DYNEIN genes encoding motility proteins which are components of sperm tails, and CILIA in the respiratory and the reproductive tracts.
Changes that occur to liberate the enzymes of the ACROSOME of a sperm (SPERMATOZOA). Acrosome reaction allows the sperm to penetrate the ZONA PELLUCIDA and enter the OVUM during FERTILIZATION.
The chromosomal constitution of cells which deviate from the normal by the addition or subtraction of CHROMOSOMES, chromosome pairs, or chromosome fragments. In a normally diploid cell (DIPLOIDY) the loss of a chromosome pair is termed nullisomy (symbol: 2N-2), the loss of a single chromosome is MONOSOMY (symbol: 2N-1), the addition of a chromosome pair is tetrasomy (symbol: 2N+2), the addition of a single chromosome is TRISOMY (symbol: 2N+1).
A glycoprotein that causes regression of MULLERIAN DUCTS. It is produced by SERTOLI CELLS of the TESTES. In the absence of this hormone, the Mullerian ducts develop into structures of the female reproductive tract. In males, defects of this hormone result in persistent Mullerian duct, a form of MALE PSEUDOHERMAPHRODITISM.
Voluntary SEXUAL INTERCOURSE between a married person and someone other than the SPOUSE.
Elements of limited time intervals, contributing to particular results or situations.
Inflammation of the ENDOMETRIUM, usually caused by intrauterine infections. Endometritis is the most common cause of postpartum fever.
The performance of surgical procedures with the aid of a microscope.
A medical-surgical specialty concerned with the physiology and disorders primarily of the female genital tract, as well as female endocrinology and reproductive physiology.
Increased levels of PROLACTIN in the BLOOD, which may be associated with AMENORRHEA and GALACTORRHEA. Relatively common etiologies include PROLACTINOMA, medication effect, KIDNEY FAILURE, granulomatous diseases of the PITUITARY GLAND, and disorders which interfere with the hypothalamic inhibition of prolactin release. Ectopic (non-pituitary) production of prolactin may also occur. (From Joynt, Clinical Neurology, 1992, Ch36, pp77-8)
Mapping of the KARYOTYPE of a cell.
A condition observed in WOMEN and CHILDREN when there is excess coarse body hair of an adult male distribution pattern, such as facial and chest areas. It is the result of elevated ANDROGENS from the OVARIES, the ADRENAL GLANDS, or exogenous sources. The concept does not include HYPERTRICHOSIS, which is an androgen-independent excessive hair growth.
Stress wherein emotional factors predominate.
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
Pathological processes involving the PERITONEUM.
A nitroimidazole antiprotozoal agent used in ameba and trichomonas infections. It is partially plasma-bound and also has radiation-sensitizing action.
Conditions or pathological processes associated with pregnancy. They can occur during or after pregnancy, and range from minor discomforts to serious diseases that require medical interventions. They include diseases in pregnant females, and pregnancies in females with diseases.
An important aggregate factor in epidemiological studies of women's health. The concept usually includes the number and timing of pregnancies and their outcomes, the incidence of breast feeding, and may include age of menarche and menopause, regularity of menstruation, fertility, gynecological or obstetric problems, or contraceptive usage.
The 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids.
Pain in the pelvic region of genital and non-genital origin and of organic or psychogenic etiology. Frequent causes of pain are distension or contraction of hollow viscera, rapid stretching of the capsule of a solid organ, chemical irritation, tissue ischemia, and neuritis secondary to inflammatory, neoplastic, or fibrotic processes in adjacent organs. (Kase, Weingold & Gershenson: Principles and Practice of Clinical Gynecology, 2d ed, pp479-508)
Short tracts of DNA sequence that are used as landmarks in GENOME mapping. In most instances, 200 to 500 base pairs of sequence define a Sequence Tagged Site (STS) that is operationally unique in the human genome (i.e., can be specifically detected by the polymerase chain reaction in the presence of all other genomic sequences). The overwhelming advantage of STSs over mapping landmarks defined in other ways is that the means of testing for the presence of a particular STS can be completely described as information in a database.
Vaccines or candidate vaccines used to prevent conception.
A genetic rearrangement through loss of segments of DNA or RNA, bringing sequences which are normally separated into close proximity. This deletion may be detected using cytogenetic techniques and can also be inferred from the phenotype, indicating a deletion at one specific locus.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
Surgery performed on the female genitalia.
The sexual functions, activities, attitudes, and orientations of an individual. Sexuality, male or female, becomes evident at PUBERTY under the influence of gonadal steroids (TESTOSTERONE or ESTRADIOL), and social effects.
The excretory duct of the testes that carries SPERMATOZOA. It rises from the SCROTUM and joins the SEMINAL VESICLES to form the ejaculatory duct.
Formation of an artificial opening in a fallopian tube.
A cutaneous pouch of skin containing the testicles and spermatic cords.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
Chemical substances having a specific regulatory effect on the activity of a certain organ or organs. The term was originally applied to substances secreted by various ENDOCRINE GLANDS and transported in the bloodstream to the target organs. It is sometimes extended to include those substances that are not produced by the endocrine glands but that have similar effects.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
The male reproductive organs. They are divided into the external organs (PENIS; SCROTUM;and URETHRA) and the internal organs (TESTIS; EPIDIDYMIS; VAS DEFERENS; SEMINAL VESICLES; EJACULATORY DUCTS; PROSTATE; and BULBOURETHRAL GLANDS).
The premature cessation of menses (MENSTRUATION) when the last menstrual period occurs in a woman under the age of 40. It is due to the depletion of OVARIAN FOLLICLES. Premature MENOPAUSE can be caused by diseases; OVARIECTOMY; RADIATION; chemicals; and chromosomal abnormalities.
Procedures to reverse the effect of REPRODUCTIVE STERILIZATION and to regain fertility. Reversal procedures include those used to restore the flow in the FALLOPIAN TUBE or the VAS DEFERENS.
Utilization or disposal of an embryo that is fertilized but not immediately transplanted and resulting course of action.
The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS.
Genes that are located on the Y CHROMOSOME.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
A slightly alkaline secretion of the endocervical glands. The consistency and amount are dependent on the physiological hormone changes in the menstrual cycle. It contains the glycoprotein mucin, amino acids, sugar, enzymes, and electrolytes, with a water content up to 90%. The mucus is a useful protection against the ascent of bacteria and sperm into the uterus. (From Dictionary of Obstetrics and Gynecology, 1988)

Sonographic evidence for the involvement of the utero-ovarian counter-current system in the ovarian control of directed uterine sperm transport. (1/2696)

Sperm transport from the cervix into the tube is an important uterine function within the process of reproduction. This function is exerted by uterine peristalsis and is controlled by the dominant ovarian structure via a cascade of endocrine events. The uterine peristaltic activity involves only the stratum subvasculare of the myometrium, which exhibits a predominantly circular arrangement of muscular fibres that separate at the fundal level into the fibres of the cornua and continue into the circular muscles of the respective tubes. Since spermatozoa are transported preferentially into the tube ipsilateral to the dominant follicle, this asymmetric uterine function may be controlled by the ovary via direct effects utilizing the utero-ovarian counter-current system, in addition to the systemic circulation. To test this possibility the sonographic characteristics of the uterine vascular bed were studied during different phases of the menstrual cycle. Vaginal sonography with the measurement of Doppler flow characteristics of both uterine arteries and of the arterial anastomoses of the uterine and ovarian arteries (junctional vessels) in the cornual region of both sides of the uterus during the menstrual phase of regular-cycling women demonstrated significant lower resistance indices of the junctional vessels ipsilateral to the side of the dominant ovarian structure as compared with the corresponding arteries contralaterally. By the use of the perfusion mode technique, it could be observed that vascular perfusion of the fundal myometrium was significantly increased ipsilateral to the dominant follicle during the late follicular phase of the cycle. These results show that the endocrine control of the dominant ovarian structure over uterine function is not only exerted via the systemic circulation but also directly, most probably utilizing the utero-ovarian counter-current system.  (+info)

Risk of testicular cancer in subfertile men: case-control study. (2/2696)

OBJECTIVE: To evaluate the association between subfertility in men and the subsequent risk of testicular cancer. DESIGN: Population based case-control study. SETTING: The Danish population. PARTICIPANTS: Cases were identified in the Danish Cancer Registry; controls were randomly selected from the Danish population with the computerised Danish Central Population Register. Men were interviewed by telephone; 514 men with cancer and 720 controls participated. OUTCOME MEASURE: Occurrence of testicular cancer. RESULTS: A reduced risk of testicular cancer was associated with paternity (relative risk 0.63; 95% confidence interval 0.47 to 0.85). In men who before the diagnosis of testicular cancer had a lower number of children than expected on the basis of their age, the relative risk was 1.98 (1.43 to 2.75). There was no corresponding protective effect associated with a higher number of children than expected. The associations were similar for seminoma and non-seminoma and were not influenced by adjustment for potential confounding factors. CONCLUSION: These data are consistent with the hypothesis that male subfertility and testicular cancer share important aetiological factors.  (+info)

Molecular analysis of the cystic fibrosis gene reveals a high frequency of the intron 8 splice variant 5T in Egyptian males with congenital bilateral absence of the vas deferens. (3/2696)

It has previously been shown that defects in the cystic fibrosis transmembrane conductance regulator (CFTR) gene are largely responsible for the condition of congenital bilateral absence of the vas deferens (CBAVD), without associated renal abnormalities, in Caucasian populations. To assess the involvement of the CFTR in CBAVD in a population with presumed low cystic fibrosis (CF) frequency, we have analysed 20 CBAVD males from Egypt for the presence of 12 common Caucasian CFTR mutations and the intron 8 5T splice variant, IVS-5T, known to be a major cause of CBAVD in Caucasian patients. In 16 of the males without associated renal abnormalities only one deltaF508 carrier was identified, but an exceptionally high frequency of the IVS-5T variant was found (14 of 32 alleles or 43.7%), confirming that this variant is involved in many cases of CBAVD, even in populations where CF is rare. CFTR mutations or the IVS-5T variant were found neither in the remaining four patients with associated renal abnormalities nor in the spouses of the 20 CBAVD patients. However, one patient was homozygous for a leucine to proline substitution at amino acid position 541 (L541P) of the CFTR. It is as yet not clear whether this change is involved in CBAVD in this male.  (+info)

Expression of CD44 in human cumulus and mural granulosa cells of individual patients in in-vitro fertilization programmes. (4/2696)

CD44 is a polymorphic and polyfunctional transmembrane glycoprotein widely expressed in many types of cells. Here, the expression of this protein on human membrana granulosa was studied by two techniques. Using confocal laser scanning microscopy (CLSM) with the mouse monoclonal antibody to human CD44 (clone G44-26), cells immunoreactive for CD44 were observed in both cumulus and mural granulosa cell masses. On the other hand, using monoclonal antibody to human CD44v9, goat polyclonal antibody to human CD44v3-10 and the clone G44-26, no immunoreactivity for CD44v9 and/or CD44v3-10 was observed in either cell group by flow cytometry. In the flow cytometric analysis of 32 patients, the incidence of CD44 expression in cumulus cells (62.6+/-1.3%) was significantly higher than that in mural granulosa cells (38.5+/-3.2%) (P<0.0001). In the comparison of CD44 expression by flow cytometry according to the maturation of each cumulus-oocyte complex, the incidence of CD44 expression of cumulus cells was significantly higher in the mature group than in the immature group (P<0.05). In a flow cytometric analysis, patients with endometriosis showed a significantly lower incidence of CD44 expression in cumulus cells compared to the infertility of unknown origin group (P<0.05), and compared to both the male infertility group and the unknown origin group in mural granulosa cells (P<0.01). These findings suggest that the standard form of CD44 is expressed in human membrana granulosa with polarity and may play an important role in oocyte maturation.  (+info)

Y chromosome and male infertility. (5/2696)

Recent genome analysis of the Y chromosome has increased the number of genes found on this chromosome markedly. Many of these genes in the part of the Y chromosome that does not undergo recombination with the X chromosome are members of gene families. Evolutionary considerations imply that genes on the Y chromosome will degenerate unless they have male advantageous or female deleterious functions. Spermatogenesis is an example of a male advantageous function and genes in three regions of the human Y chromosome have been promoted as candidate male fertility factors.  (+info)

Origin of DNA damage in ejaculated human spermatozoa. (6/2696)

The molecular basis of many forms of male infertility is poorly defined. One area of research that has been studied intensely is the integrity of the DNA in the nucleus of mature ejaculated spermatozoa. It has been shown that, in men with abnormal sperm parameters, the DNA is more likely to possess strand breaks. However, how and why this DNA damage originates in certain males and how it may influence the genetic project of a mature spermatozoon is unknown. Two theories have been proposed to describe the origin of this DNA damage in mature spermatozoa. The first arises from studies performed in animal models and is linked to the unique manner in which mammalian sperm chromatin is packaged, while the second attributes the nuclear DNA damage in mature spermatozoa to apoptosis. One of the factors implicated in sperm apoptosis is the cell surface protein, Fas. In this review, we discuss the possible origins of DNA damage in ejaculated human spermatozoa, how these spermatozoa arrive in the ejaculate of some men, and what consequences they may have if they succeed in their genetic project.  (+info)

Mouse MutS-like protein Msh5 is required for proper chromosome synapsis in male and female meiosis. (7/2696)

Members of the mammalian mismatch repair protein family of MutS and MutL homologs have been implicated in postreplicative mismatch correction and chromosome interactions during meiotic recombination. Here we demonstrate that mice carrying a disruption in MutS homolog Msh5 show a meiotic defect, leading to male and female sterility. Histological and cytological examination of prophase I stages in both sexes revealed an extended zygotene stage, characterized by impaired and aberrant chromosome synapsis, that was followed by apoptotic cell death. Thus, murine Msh5 promotes synapsis of homologous chromosomes in meiotic prophase I.  (+info)

Varicocele and infertility in men. (8/2696)

Varicocele is an important cause of infertility in men. The exact mechanism by which varicocele depresses spermatogenesis is unknown but probably the retrograde flow of blood rich in catecholamines into the testes plays a major role. Because subfertile semen qualities are present in a large percentage of men with varicocele and because the response to surgical procedures is very good, high ligation of the left internal spermatic vein is recommended in men with varicocele and infertility.  (+info)

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OBJECTIVE: To evaluate the outcomes of assisted reproductive technology (ART) cycles for male factor infertility, and method of sperm collection.. DESIGN: Historic cohort study.. SETTING: Clinic-based data.. PATIENTS: Cycles from the Society for Assisted Reproductive Technology Clinic Outcomes Reporting System database for 2004 to 2008 were limited to three groups: non-intracytoplasmic sperm injection (ICSI) and ICSI cycles for tubal ligation only; non-ICSI and ICSI cycles for male factor infertility only; and all cycles (regardless of infertility diagnosis) using ICSI only.. INTERVENTION(S) AND MAIN OUTCOME MEASURE(S): Multivariate logistic regression was used to model the adjusted odds ratio (AOR) of clinical intrauterine gestation (CIG) and live birth (LB) rates for tubal ligation versus male factor infertility only; ICSI versus non-ICSI for male factor infertility only; and ICSI outcomes based on method of sperm collection.. RESULT(S): Models for male factor infertility only versus tubal ...
Male infertility is a multifactorial disorder with impressively genetic basis; besides, sperm abnormalities are the cause of numerous cases of male infertility. In this study, we evaluated the genetic variants in exons 4 and 5 and their intron-exon boundaries in RABL2B gene in infertile men with oligoasthenoteratozoospermia (OAT) and immotile short tail sperm (ISTS) defects to define if there is any association between these variants and human male infertility.
Overview. Up to 15 percent of couples are infertile. This means they arent able to conceive a child, even though theyve had frequent, unprotected sexual intercourse for a year or longer. In over a third of these couples, male infertility plays a role.. Male infertility is due to low sperm production, abnormal sperm function or blockages that prevent the delivery of sperm. Illnesses, injuries, chronic health problems, lifestyle choices and other factors can play a role in causing male infertility.. Not being able to conceive a child can be stressful and frustrating, but a number of male infertility treatments are available.. Symptoms. The main sign of male infertility is the inability to conceive a child. There may be no other obvious signs or symptoms. In some cases, however, an underlying problem such as an inherited disorder, a hormonal imbalance, dilated veins around the testicle or a condition that blocks the passage of sperm causes signs and symptoms.. Although most men with male ...
Here you can find full and current information on infertility due to male factors, as well as diagnosing tests and treatment, In men, infertility is usually associated with a decrease in the number, quality, or motility (power of spontaneous movement) of sperm.Offers infertility clinic and human reproduction centre for infertility treatment of male and female by men infertility and women infertility specialist in Pakistan. Male Infertility causes,alternative approaches to treatment, prevention to male infertility and sperm weakness, sperm fertility treatment, natural sperm enhancement, volume and potency formula
Here you can find full and current information on infertility due to male factors, as well as diagnosing tests and treatment, In men, infertility is usually associated with a decrease in the number, quality, or motility (power of spontaneous movement) of sperm.Offers infertility clinic and human reproduction centre for infertility treatment of male and female by men infertility and women infertility specialist in Pakistan. Male Infertility causes,alternative approaches to treatment, prevention to male infertility and sperm weakness, sperm fertility treatment, natural sperm enhancement, volume and potency formula
European Association of Urology GUIDELINES ON MALE INFERTILITY G.R. Dohle, W. Weidner, A. Jungwirth, G. Colpi, G. Papp, J. Pomerol, T.B. Hargreave UPDATE MARCH 2004 TABLE OF CONTENTS PAGE 1 INTRODUCTION 1.1 Definition 1.2 Epidemiology and aetiology 1.3 Prognostic factors 1.4 Recommendations 1.5 References 6 6 6 6 7 7 2 INVESTIGATIONS 2.1 Semen analysis 2.1.1 Frequency semen analyses 2.2 Advanced diagnostic spermatological tests 2.3 Recommendations 2.4 References 7 7 7 8 8 8 3 PRIMARY SPERMATOGENIC FAILURE 3.1 Definition 3.2 Aetiology 3.3 Testicular morphology 3.4 History and physical examination 3.5 Investigations 3.5.1 Semen analysis 3.5.2 Hormonal determinations 3.5.3 Combination obstructive/non-obstructive azoospermia 3.5.4 Sertoli cell-only syndrome (SCOS) 3.5.5 Testicular biopsy 3.6 Biopsy techniques 3.6.1 Open biopsy 3.6.2 Percutaneous testicular biopsy 3.6.3 Testicular fine-needle aspiration 3.7 Treatment 3.7.1 Predictive parameters for successful TESE 3.8 TESE techniques 3.8.1 ...
According to clinical studies, around 35% of all infertility cases are related to male fertility issues. Male infertility can be caused due to several factors. Fortunately, male infertility treatment is now available at the top Fertility Treatment Clinic, Pacific Reproductive Center in Los Angeles. Male infertility can be divided into four main categories.. Pre-testicular causes. These are problems that occur due to some form of hormone deficiency, such as a problem with the pituitary gland or hypothalamus. Men who have this type of infertility often have underdeveloped male characteristics. As part of male infertility treatment at leading fertility treatment clinic, Pacific Reproductive Center Los Angeles, hormone imbalance correction can be treated using hormone replacement therapy or medications to restore body hormones.. Testicular causes. These problems can be genetic, based on birth defects, or testicular compromised from physical damage or toxins.. Sperm disorders. This includes problems ...
Male infertility is defined as a condition where the male partner is unable to make his female partner pregnant even after a year of sexual intercourse without using birth control. It is found that 20% of the total infertility i.e. male and female is because of male induced factors. One or more than one medical conditions or factors can contribute to male infertility. The significant causes include low sperm production, hormonal imbalance, abnormal sperm function or blockages in male reproductive systems. However, sometimes the symptoms or conditions causing male infertility are simply not identifiable. Although, presently, limited number of medical treatments exist at treating the symptoms of male infertility thus improving chances of female conception, the increase in number aging male population would drive the growth of the market. Diagnosing the cause of infertility may take long period and males may have to undergo a host of tests involving physical examination beginning with the concerned ...
Male factor infertility can cause genetic abnormalities such as Robertsonian translocations, androgen receptor mutations and Y chromosome microdeletions. Male factor infertility can cause failed pregnancies or produce children with genetic defects. The use of PGS can help increase chances of successful pregnancies and decrease the rates of development of children with genetic defects. However, such couples will have lower rates of conception, because there are fewer numbers of normal embryos available for implantation into the mothers womb.. With the availability of newer technologies such as PGS, male partners with male factor infertility have increased chances of producing normal children with their partners.. ...
Infertility in Men. Infertility is the medical term for a couples inability to become pregnant after one year of sexual intercourse. Based on current statistics, around 15% of couples in the U.S. and Europe have problems with conception. Fertility depends upon several factors, for both the man and the woman. Male factors contribute to 30% of infertility. In the past, men with infertility had few options. However, improvements in technology have now gave hope to many couples.. Causes of Male Infertility. For a man to be fertile, he must have a normal functioning pituitary gland and hypothalamus (hormone-producing structures of the brain), as well as adequate testicular function. Around 35% of cases of male infertility are related to problems with the testes, with around 15% being contributed to blockage in the passage of sperm. In addition, around 45% of male infertility cases have no identifiable cause.. Risk ...
If this trend continues, humans in the future will not be able to have normal pregnancy and childbirth. | No kidding! Noisy streets can cause male infertility
Male infertility is very common these days. Male Infertility can occur due to ED, Early Ejaculation, Tight Foreskin to name a few. Meet Best Doctor for Male Infertility in Delhi, India Dr. Manu and Dr. Kanu for Male Infertility Treatment with Ayurvedic Medicines only at Sidri International Skin Hair and Sexology Clinic.
Male Infertility: Male reproductive physiology, Diagnosis of Male Infertility, Causes of Male infertility, Treatment of Male infertility, Male Infertility Clinical Findings
The global male infertility market is expected to reach USD 4.7 billion by 2025, according to a new report by Grand View Research, Inc. Globally, increasing infertility in male and advancements in diagnostic tests have been major factors driving the market growth. In addition, growing consciousness regarding factors causing male infertility and Assisted Reproductive Technology (ART) has led to increased adoption of treatment.. Furthermore, increasing aging population, rising obesity, and other lifestyle-associated diseases causing infertility are likely to boost the market during the forecast period. In the U.S., one third of infertility cases are due to female factor, one third due to male factors, and remaining one third are unexplained.. DNA fragmentation technique was the largest segment in male infertility tests market in 2016 and is expected to maintain its dominance during the forecast period due to rapid growth in next few years. High cost and increasing adoption in developed countries ...
The global male infertility market is expected to reach USD 4.7 billion by 2025, according to a new report by Grand View Research, Inc. Globally, increasing infertility in male and advancements in diagnostic tests have been major factors driving the market growth. In addition, growing consciousness regarding factors causing male infertility and Assisted Reproductive Technology (ART) has led to increased adoption of treatment.. Furthermore, increasing aging population, rising obesity, and other lifestyle-associated diseases causing infertility are likely to boost the market during the forecast period. In the U.S., one third of infertility cases are due to female factor, one third due to male factors, and remaining one third are unexplained.. DNA fragmentation technique was the largest segment in male infertility tests market in 2016 and is expected to maintain its dominance during the forecast period due to rapid growth in next few years. High cost and increasing adoption in developed countries ...
The global male infertility market is expected to reach USD 4.7 billion by 2025, according to a new report by Grand View Research, Inc. Globally, increasing infertility in male and advancements in diagnostic tests have been major factors driving the market growth. In addition, growing consciousness regarding factors causing male infertility and Assisted Reproductive Technology (ART) has led to increased adoption of treatment.. Furthermore, increasing aging population, rising obesity, and other lifestyle-associated diseases causing infertility are likely to boost the market during the forecast period. In the U.S., one third of infertility cases are due to female factor, one third due to male factors, and remaining one third are unexplained.. DNA fragmentation technique was the largest segment in male infertility tests market in 2016 and is expected to maintain its dominance during the forecast period due to rapid growth in next few years. High cost and increasing adoption in developed countries ...
The global male infertility market is expected to reach USD 4.7 billion by 2025, according to a new report by Grand View Research, Inc. Globally, increasing infertility in male and advancements in diagnostic tests have been major factors driving the market growth. In addition, growing consciousness regarding factors causing male infertility and Assisted Reproductive Technology (ART) has led to increased adoption of treatment.. Furthermore, increasing aging population, rising obesity, and other lifestyle-associated diseases causing infertility are likely to boost the market during the forecast period. In the U.S., one third of infertility cases are due to female factor, one third due to male factors, and remaining one third are unexplained.. DNA fragmentation technique was the largest segment in male infertility tests market in 2016 and is expected to maintain its dominance during the forecast period due to rapid growth in next few years. High cost and increasing adoption in developed countries ...
...ESHRE invites you to attend its first workshop on male infertility in ...The workshop provides a forum for clinicians and scientists to share r...Here some of the new research findings that fertility experts from in ... Nature versus Nurture: Male reproductive disorders a gene-...,ESHREs,first,workshop,on,male,infertility,in,Thessaloniki,biological,biology news articles,biology news today,latest biology news,current biology news,biology newsletters
TY - JOUR. T1 - The effect of antioxidants on male factor infertility. T2 - the Males, Antioxidants, and Infertility (MOXI) randomized clinical trial. AU - Reproductive Medicine Network. AU - Steiner, Anne Z.. AU - Hansen, Karl R.. AU - Barnhart, Kurt T.. AU - Cedars, Marcelle I.. AU - Legro, Richard S.. AU - Diamond, Michael P.. AU - Krawetz, Stephen A.. AU - Usadi, Rebecca. AU - Baker, Valerie L.. AU - Coward, R. Matthew. AU - Huang, Hao. AU - Wild, Robert. AU - Masson, Puneet. AU - Smith, James F.. AU - Santoro, Nanette. AU - Eisenberg, Esther. AU - Zhang, Heping. PY - 2020/3. Y1 - 2020/3. N2 - Objective: To determine whether antioxidants improve male fertility, as measured by semen parameters and DNA fragmentation at 3 months and pregnancy resulting in live birth after up to 6 months of treatment, among couples with male factor infertility. Design: Multicenter, double-blind, randomized, placebo-controlled trial with an internal pilot study. Setting: Nine fertility centers in the United ...
Looking for Male Infertility? Find out information about Male Infertility. inability to conceive or carry a child to delivery. The term is usually limited to situations where the couple has had intercourse regularly for one year... Explanation of Male Infertility
Male infertility is a worldwide growing problem these days so dont hesitate, Visit now to find best male infertility treatment in delhi, infertility treatment in delhi
Many tools are available to the fertility specialist for treating male infertility.In mild cases, super-ovulation (a procedure in which the wife is given fertility drugs to stimulate formation of multiple eggs, thus increasing the possibility that any one will fertilize) with Intrauterine Insemination (IUI). With IUI, the husbands semen is washed, capacitated and concentrated and then injected directly into the uterus. When auto-immune factors are present, the sperm are first purified in a technique called sperm washing.. In Vitro Fertilization (IVF) is also frequently utilized to treat severe male factor infertility or in cases where superovulation and insemination has not been successful.. Recently, two high-tech breakthroughs have increased the odds significantly for couples with severe male infertility undergoing IVF:. Utilizing ICSI (pronounced icksy), which stands for IntraCytoplasmic Sperm Injection, a single sperm is all that is needed. It can be injected, using microscopic ...
It is evident that genetic variation plays a substantial role in the etiology of male infertility. Studies of children fathered through intracytoplasmic sperm injection or ICSI have revealed mutations on the AZF region of the Y chromosome linked to male infertility. Mutations of other genes may also be involved. Candidates would include genes for the androgen receptor, follicle-stimulating hormone, and luteinizing hormone, and genes involved in the regulation of spermatogenesis and sperm motility. Mutations in mitochondrial DNA have been linked to poor sperm motility and raise the possibility that some types of male subfertility may be inherited only through the female line.. We propose to assess the role of folate/homocysteine status and MTHFR and CBS gene variants in infertile men in Sweden with no known cause for their infertility and whose wives/partners appear to be fertile. We propose to perform the study in Sweden since Sweden, unlike the U.S., at present does not mandate the enrichment ...
Male Infertility Treatment Surgery/ Test Cost in Delhi NCR. Compare quotes for Male Infertility Treatment at top hospitals and book an instant appointment on Credihealth. Get free medical assistance from experts.
Male infertility treatments bring hope to couples facing mild or severe male factor infertility. IVF Plano offers semen analysis, ICSI for low sperm counts.
Male infertility Treatment by best sexologist in Delhi, Male infertility or the inability for a person to possess kid is on the increase in India. The reasons for this condition will embody numerous things as well as secretion imbalance, reduction of count, male reproductive gland injuries, avoirdupois and dangerous way decisions like abuse of medication, excessive intake of alcohol and unhealthy feeding habits. The strain and anxiety that male infertility causes in a wedding will result in issues not solely within their relationship however may also result in tension in the family normally. The person affected by this condition will typically feel Humiliated and depressed, and therefore the pressure he feels thanks to his family and friends will generally lead him to hunt facilitate from dubious sources like medical quacks etc and pay giant amounts of cash on treatment thats ineffective and in some cases be harmful to his health. We at Dr monga clinic specialize sexologist doctor in Delhi, in ...
Male infertility treatment in India must be cured well with proper medications and precautions to be followed which is being guided by the doctors and expert male infertility can be cured and also will not be found in the future.
Male Infertility and IVF Treatment-Overview of Male Infertility- Male Infertility Specialist-Evaluation of Male Infertility-Male Fertility Problems-Cause,diagnosis and evaluation of Male Infertility-Male Fertility or Male Infertility-Treatment for Male Infertility -IUI, IVF, ICSI and Male Fertility Issues. From the medical standpoint, a couple is considered to be infertile if there has been no pregnancy after one to…
New research examining COVID-19 and human sperm suggests potential risks for male infertility as well as sexual transmission.. Local Mississippi Breaking News Story from CBS 12 New WJTV, your Jackson, MS news leader
Ath Ayurdhamah presents an Ayurvedic perspective about Male Infertility - including symptoms of Male Infertility & Treatment of Male Infertility - by Dr. Parmeshwar Arora.
Diltiazem Side Effects Cause Male Infertility. Parker Waichman LLP is currently investigating reports of permanent male infertility.
Male infertility occurs due to low sperm production, abnormal sperm function, blockages that prevent the delivery of sperm, illnesses, injuries, chronic health problems, or lifestyle choices. Diagnostic tests such as scrotal ultrasound, hormone testing, post-ejaculation urinalysis, genetic tests, testicular biopsy and specialized sperm function test are performed for a proper diagnosis. Patients that have a sperm count less than 15 million sperm per millilitre or less than 39 million sperm total per ejaculate are considered as a major reason for Male Factor Infertility.. ...
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Use royal jelly & pollen powder for the treatment of male infertility: Treatment of male infertility using Royal Jelly & pure honey and pollen powder for treatment 49,00 EUR* ...
Whether varicocele causes male infertility and whether surgical treatment (varicolectomy) influences the pregnancy rate are two highly controversial issues. Most studies of the effects of varicolectomy fertility have been retrospective and with inadequately controlled, poorly randomized, with low number of observations, or have used changes in semen analysis rather than pregnancy rate as end points. An improvement in semen characteristics does not mean an effective improvement on pregnancy rates. As an example, you as a patient may have 1-2 million sperm/ml. Even if you experience a 100% improvement (which is very unlikely), the sperm counts after varicolectomy may not be sufficient to initiate a pregnancy. One of the most compelling reports for the use of varicolectomy as a therapy for infertility was published in 1995. It indicated that 8/25 (44.4%) couples conceived within 12 months of surgery compared to 2/20 (10%) of couples with no surgery. However, the statistical analysis revealed that ...
Up to 50% of all infertility cases are impacted by male factor infertility. If you or your partner are struggling, you arent alone. Contact us today!
The latest report about Male Infertility market Added by MarketResearch.Biz, features latest and future growth trends related to the business besides information on the many regions that belong to the geographical spectrum of the Male Infertility market. In addition, the report further explains significant details pertaining to the market size, demand and supply analysis, market share growth and contributions from top manufacturers of the Male Infertility market.. Comprising a detailed analysis of the Male Infertility Market, the research report in question is a collection of in-depth insights pertaining to the industry evaluation. The study delivers insights subject to the present market size as well, which may have quite an impact on the growth prospects of this industry in the years to come.. An insightful gist about the current trends of this business and their influence on the target remuneration of the Male Infertility market has been provided in the report. An understanding of the ...
Objectives: To identify male factor infertility among a group of patients in an assisted reproductive program (phase 1) and to evaluate the hemizona assay (HZA) in the diagnosis and prognosis of such a program (phase 2). Design: The IVF performance of normal gametes in the Tygerberg program were critically evaluated. Female patients were classified as pure tubal factor infertility, having a normal FSH:LH ratio on day 3 of the menstrual cycle. All participating women produced three or more preovulatory oocytes at retrieval and were inseminated with sperm considered normal by all present diagnostic criteria. The total and normal fertilization rate thresholds were defined in that group. Using those thresholds, couples tested for sperm binding in the HZA (n = 48) were used and divided into two groups according to their fertilization rates, namely group 1, low fertilization (,55%) and group 2, normal fertilization (,55%). Setting: University-based tertiary care center. Patients: Ninety-nine couples ...
Background Lipid peroxidation of sperm plasma membranes has a deleterious effect on the semen quality, and measurement of malondialdehyde acid (MDA) is the most widely used method for assessing lipid peroxidation. High levels of seminal MDA represent increased lipid peroxidation rates and oxidative damage to the sperm plasma membranes, which may result in the impairment of the integrity and functioning of sperm plasma membranes and damage of both nuclear and mitochondrial DNA. Aim of the study The aim of the present study was to investigate the seminal plasma MDA concentration as a marker of lipid peroxidation and its correlation with the hypo-osmotic swelling test (HOST) scores as a predictor for the functional integrity of the sperm membrane in cases of idiopathic male infertility. Participants and methods A total of 93 men were included in this study: 68 men who had been attending to our andrology outpatient clinics with idiopathic infertility were selected as cases and 25 healthy fertile men ...
Dear Linda,. Given all the specific factors that you present, we cant give you a statistic on how acupuncture will improve your and your husbands ability to conceive. We know that IVF increased fertility success rates from 26% to 41% in the 200 or so participants in the German study, but we need to include your husbands issues as well.. Generally, herbal prescriptions have been documented to help improve sperm motility and decrease sperm defects. This research has mostly been done in China, where subjects are willing to take large doses of raw herbs. I would suggest you read this article on male infertility by Randine Lewis, PhD, LAc, author of The Infertility Cure.. You may need to contact a specialist in Chinese medicine infertility, and you might possibly need to travel for treatment. Overcoming infertility can be tiring and expensive. Acupuncture and herbs are relatively inexpensive compared to IVF, and since there is a good chance theyll increase the likelihood that your first or second ...
Medical Problems. Varicocele: This condition refers to the abnormal diffusion of the veins that causes the testicles to drain. Though this is regarded as one of the most reversible causes of male infertility, it highly affects the quantity and quality of sperm produced. This is also associated with an abnormal increase in the temperature around the testicles. Sperm count and function could be improved via the surgical treatment of Varicocele and this treatment has the potential to improve the results especially when associated with assisted reproductive techniques like in-vitro fertilization or intracytoplasmic sperm insemination.. Trauma: Testicular trauma, is one of the most leading cause of male infertility where the testicles are present outside the abdomen, making it more prone to vulnerabilities of physical and thermal traumas.. Antibodies Attacking the Sperm: This is referred to be a condition wherein there is an abnormal immune response causing the antibodies to attack its own ...
Excessive amounts of reactive oxygen species (ROS) cause a state of oxidative stress, which result in sperm membrane lipid peroxidation, DNA damage and apoptosis, leading to decreased sperm viability and motility. Elevated levels of ROS are a major cause of idiopathic male factor infertility, which is an increasingly common problem today. Lycopene, the most potent singlet oxygen quencher of all carotenoids, is a possible treatment option for male infertility because of its antioxidant properties. By reacting with and neutralizing free radicals, lycopene could reduce the incidence of oxidative stress and thus, lessen the damage that would otherwise be inflicted on spermatozoa. It is postulated that lycopene may have other beneficial effects via nonoxidative mechanisms in the testis, such as gap junction communication, modulation of gene expression, regulation of the cell cycle and immunoenhancement. Various lycopene supplementation studies conducted on both humans and animals have shown promising ...
Infertility is a common condition in modern society, and can affect up to 15% of couples, according to the World Health Organisation (WHO).. The prevalence of infertility is likely to increase with urbanisation and deferred childbearing ages.. Although the vast majority of the etiology of infertility is related to female partners, male infertility can affect up to 40% of all the causes of infertility.. Low sperm count is also known as oligospermia. Why men face declining sperm counts is shrouded with uncertainty.. Carlsen and the co-workers revealed a shocking finding that sperm count halved between 1938 and 1990.. This was also backed by another French investigation of 26,000 sperm samples in the fertility clinic between 1989 and 2005.. The study demonstrated that the average number of sperms had fallen by one third over 17 years to the low level of 50 million/ml.. Certain lifestyle changes had been advocated by researchers to improve sperm number. Although some are backed by scientific ...
Health,Infertility affects nearly 15 percent of all couples trying to conceiv...With this being the clinical scenario the number of couples opting ...But surprisingly the results of the treatment outcome are not rel...The new research has the strength of being prospective and therefo...The results of the pre-treatment questionnaire showed no differenc...,Will,anxiety,regarding,fertility,treatment,affect,the,chances,of,conception?,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Than usual, does topamax cause infertility you might swing suddenly from happy to sad, then we used does topamax cause infertility a combination of prime-time ican spend more time with my children playing and doing things that are important. If the patient notes nearly 1 in 4 men experience ED and the study concluded that the danach.. Sellers online use MWE photos suponemos que quieras comprar Viagra for the particular expiry particular date and in addition course of usage before taking the capsule. Development may themselves prompt a greater need for treatment any alcohol since I started the medication about this, check with your doctor. Ricevendo quattro indipendenti lot more that could the drug can increase heart rate and can elevate BP, both drugs, as stated, have significant side effects, bupropion was generally well tolerated in this study. Dare say, the military this medication may cause complex nodules 1.5 centimeters to 2 centimeters also should undergo this procedure. For the depressed ...
The herpesvirus family comprises several widespread infectious pathogens. They infect a variety of animal hosts, including humans and cause complex clinical outcomes. Recently, the possible correlation between genital infection by human herpesviruses (HHVs) and male infertility has attracted considerable attention. In this chaper, we investigated the mechanism of HHV‐1‐induced infertility in transgenic (Tg) rats and its possible correlation with infertility in human males. Ectopic expression of HHV‐1 thymidine kinase (TK) in the testis of Tg rats increased male infertility. In addition, truncated TK proteins were found in postmeiotic spermatids of Tg rat testis, leading to progressive degeneration of germ cells and vacuolization of the seminiferous epithelium. These findings suggest the possibility that a similar process occurs within HHV‐infected human germ cells.
Infertility & Causes Male Infertility Infertility in the male may be due to insufficient sperm production, sub-optimal motility and/or progression, . Also we have Natural cycle IVF treatment in Cyprus
Polymorphisms in the folate-metabolizing genes could be associated with the risk of male infertility, but further studies having more statistical power are needed to investigate the association.
Buy This Report @ https://www.reportsnreports.com/purchase.aspx?name=4071760. Table of Contents:. Chapter 1 - Report Overview. Chapter 2 - Global Growth Trends. Chapter 3 - Competition Landscape by Key Players. Chapter 4 - Male Infertility Treatment Breakdown Data by Type (2015-2026). Chapter 5- Male Infertility Treatment Breakdown Data by Application (2015-2026). Chapter 6 - North America. Chapter 7 - Europe. Chapter 8 - China. Chapter 9 - Japan. Chapter 10 - Southeast Asia. Chapter 11 - Key Players Profiles. Chapter 12 - Analysts Viewpoints/Conclusions. Chapter 13 - Appendix. List of Tables:. Table 1. Global Male Infertility Treatment Market Size Growth Rate by Type (US$ Million):2016 VS 2021 VS 2027. Table 2. Key Players of DNA Fragmentation Technique. Table 3. Key Players of Oxidative Stress Analysis. Table 4. Key Players of Microscopic Examination. Table 5. Key Players of Sperm Agglutination. Table 6. Key Players of Computer Assisted Semen Analysis. Table 7. Key Players of Sperm ...
Polychlorinated Biphenyls (PCBs) are no longer commercially produced in the United States, but continue to wreak havoc on our health today. New research published in the journal Environmental Health Perspectives has linked PCBs and other environmental chemicals to sperm abnormalities and male infertility.. Previous studies have found that infertility affects 15% of couples, but that about 50% of male infertility is potentially correctable. Infertility is defined as the inability to conceive after one year of unprotected intercourse.. Melissa Perry ScD MHS, professor and chair of the Department of Environmental and Occupational Health at the George Washington School of Public Health and Health Services, led an observational study on environmental exposure to organochlorine chemicals. The research team studied 192 men who were part of couples that were sub-fertile - meaning that they had a lower ability to become pregnant than normal, healthy couples. Blood was sampled for the presence of ...
Infertility affects 1 in 6 couples and approximately 1 in 25 men. Male factor infertility is a major cause of spermatogenic anomalies, the causes of which are largely unknown. Impaired repro-ductive functions in men might result from physiological, genetic, and/or environmental factors such as xenobiotics. The multi-drug re-sistance1 (MDR1) gene encodes a P-glycoprotein which has a role in the active transport of various substrates providing protection of somatic cells from potentially toxic substances, including xenobi-otics. MDR1 is highly expressed at the luminal surface of capillary endothelial cells, and is expressed in Leydig cells, testicular mac-rophages, and Sertoli cells. We performed genotype and haplotype analyses of MDR1 in 192 infertile and 102 fertile Turkish men for the genetic markers C1236T and C3435T, using polymerase chain reaction-restriction fragment length polymorphism analysis. In the overall population, correlations were analyzed in all genotype mod-els. We found that ...
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article{2049007, abstract = {BACKGROUND: Male factor and idiopathic infertility contribute significantly to global infertility, with abnormal testicular gene expression considered to be a major cause. Certain types of male infertility are caused by failure of the sperm to activate the oocyte, a process normally regulated by calcium oscillations, thought to be induced by a sperm-specific phospholipase C, PLCzeta (PLC zeta). Previously, we identified a point mutation in an infertile male resulting in the substitution of histidine for proline at position 398 of the protein sequence (PLC zeta(H398P)), leading to abnormal PLC zeta function and infertility. METHODS AND RESULTS: Here, using a combination of direct-sequencing and mini-sequencing of the PLC zeta gene from the patient and his family, we report the identification of a second PLC zeta mutation in the same patient resulting in a histidine to leucine substitution at position 233 (PLC zeta(H233L)), which is predicted to disrupt local protein ...
BACKGROUND: Male factor and idiopathic infertility contribute significantly to global infertility, with abnormal testicular gene expression considered to be a major cause. Certain types of male infertility are caused by failure of the sperm to activate the oocyte, a process normally regulated by calcium oscillations, thought to be induced by a sperm-specific phospholipase C, PLCzeta (PLCζ). Previously, we identified a point mutation in an infertile male resulting in the substitution of histidine for proline at position 398 of the protein sequence (PLCζ(H398P)), leading to abnormal PLCζ function and infertility. METHODS AND RESULTS: Here, using a combination of direct-sequencing and mini-sequencing of the PLCζ gene from the patient and his family, we report the identification of a second PLCζ mutation in the same patient resulting in a histidine to leucine substitution at position 233 (PLCζ(H233L)), which is predicted to disrupt local protein interactions in a manner similar to PLCζ(H398P) and was
Male infertility is most commonly due to problems with sperm; either quantity, motility, or size and shape can impacts ones ability to conceive. One of the most common cause of male infertility is a varicocele, which is found in 40 percent of infertile men. A varicocele is a group of dilated veins in the scrotom. For most men they dont cause any issues and thus require no intervention. Some, however, can experience pain or impaired fertility. The dilated vessels increase the temperature of the scrotum, resulting in testicular damage and impaired sperm production. For that reason, when a couple is having difficulty conceiving and all other causes of an abnormal sperm analysis have been ruled out repair of the varicocele is recommended ...
Low sperm count is the most common reason for male infertility. Structural causes of male infertility include issues with sperm delivery and varicoceles.
Adult men with autoimmune conditions are commonly prescribed anti-tumor necrosis factor (anti-TNF) agents; however, there is a paucity of quality evidence as to their effect on male fertility (e.g. semen parameters and sperm quality). Our objective was to determine if men with autoimmune conditions are being counseled regarding the unknown reproductive effects of anti-TNF agents prior to initiation of therapy. A retrospective analysis of 1010 male patients age 18-45 who were prescribed an anti-TNF agent were assessed for (1) receipt of counseling regarding potential reproductive effects; (2) screening for anatomic or laboratory abnormalities associated with infertility; (3) election for sperm cryopreservation. Only 10.3% of men received counseling, and this was not associated with age (p = 0.77). Those who received counseling were significantly more likely to have a genitourinary exam performed, be assessed for presence of a varicocele, be asked about or endorse low libido or erectile dysfunction, have
PINA-NETO, J.M. et al. Somatic cytogenetic and azoospermia factor gene microdeletion studies in infertile men. Braz J Med Biol Res [online]. 2006, vol.39, n.4, pp.555-561. ISSN 1414-431X. http://dx.doi.org/10.1590/S0100-879X2006000400017.. The objective of the present study was to determine the frequency of somatic chromosomal anomalies and Y chromosomal microdeletions (azoospermia factor genes, AZF) in infertile males who seek assisted reproduction. These studies are very important because the assisted reproduction techniques (mainly intracytoplasmic sperm injection) bypass the natural selection process and some classical chromosomal abnormalities, microdeletions of AZF genes or some deleterious genic mutations could pass through generations. These genetic abnormalities can cause in the offspring of these patients male infertility, ambiguous external genitalia, mental retardation, and other birth defects. We studied 165 infertile men whose infertility was attributable to testicular problems (60 ...
Male infertility occurs when a man cannot produce enough sperm of adequate quality to establish a pregnancy. Sperm are sensitive to temperature changes and the body has evolved means to insure constant testicular temperature. Interestingly, sperm require three months to develop so a semen analysis done today reflects conditions three months prior. This prolonged development period also makes drug treatment of male infertility difficult.. The testicles are contained within the scrotum which expands or contracts in response to temperature. When testicular temperature is too hot the scrotum expands to move the testicles away from the body. When the temperature is too cold the scrotum contracts bringing the testicles closer to the body. Any activity that interferes with testicular temperature control can lead to decreased fertility.. For example, tight fitting clothes do not allow the scrotum to expand and perform its cooling function. Some occupations require prolonged sitting, such as a long ...
Intracytoplasmic sperm injection (ICSI) is a process requiring only one single sperm to be injected into each egg. It is considered by many to be the greatest advance for the treatment of male infertility.
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With increasing evidence for faulty paternal contribution to reproduction, there has been a steady increase in studies highlighting an association between sperm DNA damage, failed/delayed fertilisation and aberrant embryo development.Owing to prevailing ambiguity, the aims of the study were to analyse the genetic integrity of the male gamete and then to understand its association with age, standard semen parameters, lifestyle and occupational factors. The study included 504 subjects, attending university infertility clinic for fertility evaluation and treatment. Semen characteristics were analysed by standard criteria; terminal deoxynucelotidyl transferase-mediated nick end-labelling assay was employed for DNA damage assessment. The average incidence of sperm DNA damage in patients with normozoospermic semen parameters was ,10%. Patients with oligozoospermia, severe oligozoospermia, oligoasthenoteratospermia, asthenoteratozoospermia and necrozoospermia had significantly higher level of sperm DNA ...
Your doctor will try to improve your fertility by either correcting an underlying problem (if one is found) or trying treatments that seem like they may be helpful. Often, an exact cause of infertility cant be identified. Even if an exact cause isnt clear, your doctor may be able to recommend treatments that work. In many cases of infertility, the female partner also will need to be checked and may need treatment.. Treatments for male infertility include surgery, surgical retrieval of sperm, treating infections, treatments of sexual dysfunction, hormone treatments and assisted reproductive tecniques (ART) as ICSI.. Until recently, men with Non Obstructive Azoospermia (NOA) were considered sterile, and donor sperm insemination or adoption recommended as the only means of having a family. Several observations have changed the approach to this condition. Direct evaluation of testis biopsy specimens often demonstrates sperm in men with non-obstructive azoospermia, but not at high enough levels ...
From a Mens Health Science Newsgroup on male infertility: Although autoimmunization to spermatozoa is a cause of male infertility, the cause of antibody formation is unknown in most cases. It has been shown that the titer is usually unchanged for as much as 16 years in the same individual. Trials to reduce the titer with varying methods have not been successful. A new possibility of treatment was indicated by the finding of a higher incidence of prostatitis in men with sperm antibodies than in a control group. Following treatment of prostatitis we observed a reduction of the antibody titer in eight cases. In five cases the cervical mucus penetrating capacity of the spermatozoa improved, and conception occurred.. To make this clearer. They are simply stating that it would seem prostatitis starts much earlier than is usually suspected or known and that treating men for prostatitis early on would help with male infertility associated with weak mucus penetrating capabilities.. ...
TY - JOUR. T1 - Deconvolutian analysis of bioassayable LH secretion and half-life in men with idiopathic oligoasthenospermia. AU - Reyes-Fuentes, A.. AU - Chavarría, M. E.. AU - Aguilera, G.. AU - Rosado, A.. AU - Iranmanesh, A.. AU - Veldhuis, J. D.. N1 - Copyright: Copyright 2018 Elsevier B.V., All rights reserved.. PY - 1997. Y1 - 1997. N2 - To further investigate the nature of neuroendocrine disturbances of the hypothalamopituitary-gonadal axis in idiopathic male infertility, we studied 12 infertile men with oligoasthenozoospermia and 13 euspermic controls, matched for age and body mass index, by blood withdrawal at 10-min intervals for 8 h to analyse pulsatile release of bioactive LH (b-LH). The rat interstitial cell testosterone (RICT) bioassay was used in conjunction with a recently validated multiparameter deconvolution algorithm, to estimate the endogenous half-life of b-LH, its secretory burst frequency, amplitude, duration and mass. Oligoasthenospermic men exhibited significant (p , ...
BACKGROUND: One couple out of 6 consults for infertility during their sexual life. In 60% of cases a male factor is associated or is the main infertility factor. Inflammatory Syndrome (IS), characterized by the presence of a leukocytospermia is found in 12% of the cases. Leukocyte degranulation causes oxidative stress (OS) through the formation of free radicals attacking the sperm cell functions.. HYPOTHESIS: To establish the responsibility of the IS, and OS, in chronicle inflammatory male infertility, the investigators hypothesize that its treatment (as well as its possible cause) must restore or improve the fertilizing capacity of patients sperm.. METHODS: This prospective randomized study will test the response to the treatment. The investigators shall measure cellular degradation products due to the OS, thereby certifying that it does have a deleterious effect on sperm cell. Seminal biochemistry will also assess the impact of the syndrome on the genital tract glands and follow its ...
Infertility in men is a rising trend. More and more couples are finding it difficult to conceive and the chances of men being infertile are 50/50. The main causes for male infertility are low sperm count and unhealthy sperms.
It is estimated that both the partners are at an equal risk of suffering from infertility. Nearly 40 percent of the infertility cases are due to male infertility, contrary to the popular belief that only females are infertile.. IVF treatment comes into the picture when all other traditional infertility treatment methods, such as use of medications and careful monitoring of the egg have failed. It is one of the several advanced infertility treatment options recommended by a fertility specialist to infertile couples.. During a typical IVF process, the egg recovered from the mother-to-be or a donor mother is cultured and made to fertilize with a sperm in laboratory condition. One of the healthy embryo is placed into the womb of the mother at blastocyst stage, where rest of the development takes place.. The best hospitals for IVF treatment have state-of-the-art laboratories housing incubators and other machines to conduct IVF procedure safely, efficiently and successfully. The top infertility ...
I want to get my belly button peirced with my friends this summer, but I have heard from many people that it can cause infertility. I deffinatly want to have children later in life. Does it really cause infertility?
Please inform us if you are on any medications, vitamins, or herbal supplements.. *If you are prescribed an antibiotic, please complete your antibiotic regimen prior to collecting your semen specimen.. *Please fill out the Andrology Laboratory Requisition Form and complete all other forms attached.. *After collection, close the lid of the container tightly.. *If collecting at home, place the specimen container into the bag and deliver it to the laboratory preferably within one hour of collection. Ensure that the specimen is transported at body temperature or lower.. *The sample should be brought to the laboratory with the completed Chain of Custody Form provided by the receptionist.. *Never leave the specimen unattended. It has to be given directly to the laboratory personnel. The sample will not be processed unless this rule has been followed.. *If we diagnose male infertility ,failing to find any motile sperm cells in the ejaculate, you will be referred to a urologist for further work up. ...
Male infertility refers to a condition where a male is unable to impregnate a fertile female. Male infertility is caused due to deficiencies in his semen. A mans fertility depends on both the quality and quantity of his sperm. The total number of sperm a man ejaculates is important as a low sperm count is one of the major reasons that accounts for him failing to initiate a pregnancy.. Other major causes of male infertility include the failure of the testes to make sperm, sperm transport problems, and low levels of hormones made in the pituitary gland. IVF is a remedy for male infertility as it provides a platform for intra-cytoplasmic sperm injection, a laboratory technique procedure that is used in the treatment of various infertility problems. This technique enhances the fertilization phase by injecting a single sperm into a mature egg and has proven to be extremely effective in allowing a female to conceive after insertion into the uterus.. ...
Acupuncture for male infertility, low sperm count, poor sperm morphology, poor sperm mobility. Acupuncture can improve sperm count and quality.
One in six couples has difficulty in starting a family and 40% of these problems are related to the man. Until now, there have been few accurate ways of measuring a mans fertility. Traditionally, the diagnosis of male infertility has relied on a semen analysis. This test provides the basic information on which fertility specialists need to make their initial diagnosis. However, their clinical value in assessing fertility or predicting success with fertility treatment is very limited, particularly if the semen analysis results are normal.. ...
One of the most common questions I see asked is, How can I get pregnant? Infertility affects ten percent of the reproductive population in the United States according to the American Society for Reproductive Medicine. Many couples can overcome the challenge of trying to conceive through lifestyle changes.. Infertility affects both men and women. In approximately 40% of couples, male infertility contributes to or is the sole cause of their infertility. Lifestyle changes can have a dramatic impact on fertility. These tips will help both women and men increase their chances of getting pregnant.. For women.... * Use an ovulation prediction kit. This will let you know 24-48 hours before you ovulate so you can time your trying to conceive appropriately. When the test shows positive, you and your partner should have sex that day and the day after.. * Chart your basal body temperature. This provides you with a record of what is going on with your cycle. Not only will you be able to tell the day you ...
Supplementary MaterialsSupplementary Statistics. and offers book pathogenic variations for gene concentrating on of man infertility. PV leads to the abnormalities of mouse male germ cells and significant boost of apoptosis in these cells [6]. Weve compared transcriptomic information of individual regular male germ cells and discovered several potential essential genes with particular expression patterns mixed up in regulation of individual spermatogenesis [7]. Even so, extremely small is well known in regards to the hereditary flaws or PV in charge of male infertility. Studies around the genetic elements that impact male infertility could add novel insights into understanding the etiology of male factor infertility and offer new targets for gene therapy of male infertility. Transcription factor forkhead box protein P3 (FOXP3) belongs to the forkhead-winged-helix family of transcriptional regulators. FOXP3 is a well-recognized characteristic of regulatory T (Treg) cells that control immune ...
Herbal treatment for male infertility is the best male fertility product that increases healthy semen production enabling large volume of ejaculation thereby more number of healthy sperms.
INTRODUCTION: The aim of this study is to comprehensively evaluate whether FSH administration to the male partner of infertile couples improves pregnancy rate, spontaneously and/or after assisted reproductive techniques (ART). METHODS: Meta-analysis of controlled clinical trials in which FSH was administered for male idiopathic infertility, compared with placebo or no treatment. Randomization was not considered as an inclusion criterion. RESULTS: We found 15 controlled clinical studies (614 men treated with FSH and 661 treated with placebo or untreated). Concerning the type of FSH, eight studies used recombinant FSH, whereas seven studies used purified FSH. Nine studies evaluated spontaneous pregnancy rate, resulting in an overall odds ratio (OR) of about 4.5 (CI: 2.17-9.33). Eight studies evaluated pregnancy rate after ART, showing a significant OR of 1.60 (CI: 1.08-2.37). Sub-dividing studies according to the FSH preparations (purified/recombinant), pregnancy rate improvement remained ...
Intracytoplasmic Sperm Injection (ICSI) has revolutionized the treatment of male-factor infertility by allowing men who were previously incapable of producing adequate sperm to father genetically related children.. ICSI involves the placement of a single sperm directly into the egg using a microscopic pipette. Men normally produce millions of sperm in each ejaculate. These sperm swim through the cervical opening and into the tubes to the site of fertilization. Some men have sperm defects such as a reduced sperm count, deformed sperm, or sperm that cannot swim effectively. When any one of these abnormalities is present it can prevent normal fertilization. ICSI bypasses sperm defects because a single sperm is selected and placed inside the egg. ICSI is performed as a part of the IVF cycle. During IVF, the eggs are retrieved from the ovaries and taken to the embryology laboratory. In ICSI, a stereomicroscope is used to manipulate the egg(s). The egg is held in place while it is punctured by the ...
A varicocele is a scrotal abnormality defined by elongated, dilated and tortuous veins that drain the testicle.Varicocele is found in approximately 15% of the general population, 35% of men with primary infertility and in 75-81% of men with secondary infertility. It is more common on the left side. 40% of infertile men have varicoceles. And …. Is Surgery of Varicocele Necessary for Infertility treatment ? Read More » ...
The inability to procreate affects both men and women. Male infertility contributes to as much as 50% of fertility issues for couples.
In 2014, nearly 15% of the Indian population, both male and female, were infertile, according to statistics. Factors like working style can cause infertility in both men and women who live in the city. In men, infertility is predominantly due to inebriation, lifestyle and environment, where as in women, disorders like polycystic ovaries or PCD are the major cause for infertility.. A common misconception is virile men are fertile. There is no correlation between fertility and virility. Another common misconception is that a mismatch between the blood groups of a couple trying to have a baby, can cause infertility. Experts say, another reason why infertility is on the raise in women today, is because they are waiting until older to have a baby now more than ever. However infertility can be a problem for any woman, whether she is young or old, single or married.. Some of the main reasons apart from stress and unhealthy lifestyle habits are not ovulating; blocked fallopian tubes; poor egg ...
Intracytoplasmic Sperm Injection (ICSI) has revolutionized the treatment of male-factor infertility. The ideal treatment, when surgical and medical management fails to improve sperm function, is in vitro fertilization (IVF) and embryo transfer (IVF/ET), usually accompanied by Intra-cytoplasmic sperm injection (ICSI). It allows men who were previously incapable of producing adequate sperm, to father genetically related children. ICSI involves the placement of a single sperm directly into the egg using a microscopic pipette.. Men normally produce millions of sperm in each ejaculate. Sperm swim through the cervical opening and into the tubes to the site of fertilization. Some men have sperm defects such as a reduced sperm count, deformed sperm, or sperm that cannot swim effectively. When any one of these abnormalities is present, it can prevent normal fertilization.. ICSI bypasses sperm defects because a single sperm is selected and placed inside the egg. ICSI is performed as a part of the IVF ...
À travers les trois billets précédents traitant de linfertilité, vous avez pu acquérir maintes informations pouvant vous éclairer sur diagnostic lui-même de linfertilité, des facteurs de risques à la fertilité puis des tests que les femmes en investigation pourraient être susceptibles de passer pour mieux comprendre la problématique de conception spontanée.. In the three previous articles about infertility, you have learned about an infertility diagnosis, risk factors and tests women can take to understand their reproductive issues.. However, fertility issues affect both men and women. This is why I want to talk about the different tests men may have to take when facing infertility issues. 50% of men will have fertility problems, and unfortunately, we know that they consult very late, wait longer before starting the testing process. Many will refuse to believe the doctor when they diagnose infertility because it affects their masculinity, their ability to make life, produce ...
Inguinal varicocelectomy was performed on 27 selected infertile males with Grade III varicoceles. Follow up was effected for eighteen months. 18 (66%) patients recorded improvement in sperm count to above (20 X 10(6)/ML). 17 (63%) patients recorded improvement in active sperm mortility to above 40%. 15 (55%) patients showed diminution in the level of abnormal sperms to less than 30% abnormal forms. A pregnancy rate of 33.3% was recorded. These findings indicate that varicocelectomy is effective in the management of carefully selected infertile males with varicoceles in conformity with the findings of previous other studies ...
The sexual and reproductive health specialists at Tennessee Urology are specially trained to diagnose and effectively treat male factor infertility.
Definition. Infertility implies an apparent failure of a couple to conceive, while sterility indicates absolute inability to conceive. Primary infertility is I conception has never occurred and secondary infertility is if the patient fails to conceive after having produced a child or had a miscarriage. Causative factors. In Male- Systemic diseases like diabetes and obesity, endocrine disorders like pituitary infantilism, hypothyroidism, adrenal hyperplasia are important causes. Similarly factors like heavy smoking, alcoholism, nervous ension about sex, and psychological problems can also be responsible. Geital factors like defective spermatogenesis, testicular atrophy following mumps, Infections like gonococcal and tubercular in the genital tract, and aging above 45 can cause this disorder. The normal seman analysis shows sperm count 60 to 120 million per ml. with motility 80 to 90 percent. Azospermia denotes absence of sperms. Oligospermia is mild when the count is 80 million, moderate 50 ...
The infertility is not a disease - it is a consequence of a breach in the body. May be due to improper development or disease of the reproductive system of one of the partners, endocrine disease, mental or neurological disease. The infertility is a problem of both sexes, so it is incorrect to say that the inability to conceive is the only woman. According to the statistics the infertility in women and men is virtually identical. Sometimes the cause is and sexual incompatibility, so it is sometimes enough to change the partner and children to come. Experts advise when doing research for infertility, such be subjected to both partners to be able to find the cause of infertility and to rectify the problem (if possible) early on. For infertile couples are considered one in which several years of regular intercourse without using contraception, a woman is not pregnant. According to research, even if it does not cause infertility, though some couples do not get to have kids. It is possible to cause ...
The causes of infertility discussed above are rooted in the Western, bio-medical paradigm and it is important to understand that infertility is understood differently in each sociocultural context in which it is experienced. Traditional knowledge in Anglophone Africa acknowledges both male and female causes of infertility, however in patriarchal societies men are protected and women are almost always blamed for involuntary childlessness. In Tanzania, for example, medical treatment for infertility is often delayed or precluded in favour of traditional and religious treatments because evil forces are often thought to be the cause of infertility. In Latin America, strong social stigma is attached to infertility and machismo attitudes create a dynamics where women blame themselves for infertility. In the Far East, Confucian texts recognize three elements that control reproduction, a male component, a female and an element with comes from both male and female. Infertility however is usually blamed on ...
This paper by Fiona Parrott examines how mens reproductive bodies are problematised in rural northern Malawi as access to biomedically defined diagnoses of the health of mens sperm contribute to the visibility of male infertility
Hodžić A, Ristanović M, Zorn B, Tulić C, Maver A, Novaković I, Peterlin B. PLoS One. 2013;8(3):e59220. A case-control study was performed to determine the role of circadian genes in male infertility. The study consisted of 517 cases and 444 controls, all of which were of Slavic origin and recruited from three outpatient fertility centres. A chi-square test found…
Research proves that consuming argan oil daily increases testosterone and benefits in male infertility. Here is how you can use argan oil to boost testosterone levels.
Alexander N. Yatsenko, M.D., Ph.D., Andrew P. Georgiadis, B.A.D., Andrea J. Berman, Ph.D., Thomas Jaffe, M.D., Marta Olszewska, Ph.D.D., Joseph Sanfilippo, M.D., Maciej Kurpisz, M.D., Ph.D., Aleksandar Rajkovic, M.D., Ph.D., Svetlana A. Yatsenko, M.D., Sabine Kliesch, M.D., Stefan Schlatt, Ph.D.D.: X-Linked TEX11 Mutations, Meiotic Arrest, and Azoospermia in Infertile Men Nearly half of most cases of male infertility are usually associated with genetic defects.1-3 Up to 20 percent of infertile men receive a analysis of azoospermia.3 Nonobstructive azoospermia is spermatogenic failure that is defined by the lack of spermatozoa in the ejaculate.1,4 Azoospermia is a heterogeneous condition with several histologic phenotypes.6,7 Azoospermia with meiotic arrest is a milder type of infertility with a cessation at the spermatocyte stage of germ-cell development.The types of addictions are as follows: * Drug Addiction * Food Addiction * Alcoholism * Internet Addiction * Sexual Addiction * Buying ...
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The first male infertility and impotence clinic in a hospital set up in eastern India was launched by Apollo Gleneagles Hospitals (AGH) recently.
Expertly authored, this text provides a practical, problem-oriented approach devoted exclusively to the surgery of male infertility. Step-by-step descriptions along with clearly illustrated drawings and photographs present the essential elements of each technique. Each chapter concludes with a section devoted to difficult judgement calls, technical pearls and an honest assessment of results.
Although it makes sense, it may still surprise you that half of all infertility cases can be attributed in part or in full to the man (aka male factor infertility). The good news is that most men are constantly producing new sperm and with the right lifestyle changes a man can significantly increase his sperm count and motility, improve their morphology, and increase their overall male fertility. Pro tip: Sperm takes anywhere from 40-80 ish days to develop from start to finish, so it is ideal if
Male infertility[edit]. While CoQ10 can improve some measurements regarding sperm quality, there is no evidence that CoQ10 ... "Coenzyme Q10 and male infertility: a meta-analysis". Journal of Assisted Reproduction and Genetics. 30 (9): 1147-1156. doi: ... "Pharmacokinetic study of deuterium-labelled coenzyme Q10 in man". International Journal of Clinical Pharmacology, Therapy, and ...
In males with KS/CHH, infertility is primarily due to the lack of sperm production within the testes. Sperm production can be ... Males with KS/CHH are normally at stage I or II with genitalia, females at stage I with breast development and both males and ... Hypogonadism due to low levels of testosterone in men or oestrogen/progesterone in women. Infertility. Total lack of sense of ... Kallmann syndrome occurs about 4 times more often in males than females, but is only 2.5 times more common among males in ...
Male infertility; Post-traumatic stress disorder; Child abuse by part of a teacher or parent; Child abuse in general; Bed ...
Though there is no FDA indication for the use of clomiphene in male infertility, it has been prescribed since the 1960s. As of ... Chehab M, Madala A, Trussell JC (March 2015). "On-label and off-label drugs used in the treatment of male infertility". ... Willets AE, Corbo JM, Brown JN (July 2013). "Clomiphene for the treatment of male infertility". Reproductive Sciences (Review ... de Kretser DM (March 1997). "Male infertility". Lancet (Review). 349 (9054): 787-90. doi:10.1016/s0140-6736(96)08341-9. PMID ...
have reviewed evidence that smoking is associated with increased sperm DNA damage and male infertility. Smoking cannabis can ... The amount of decline among men in North America and men in Australia/Europe is similar. The decline in sperm count among men ... May 2008). "Cancer Risk in Male Factor-infertility". Placenta. 29: 178-183. doi:10.1016/j.placenta.2008.07.014. PMID 18755508 ... "Understanding Semen Analysis". University Hospital & Medical Center at Stony Brook Male Infertility Program. Archived from the ...
Immunopathology and Infertility. In: Infertility in the Male, 3rd ed. Edited by LI Lipshultz and SS Howards. Mosby Year Book, ... Surgery or assisted reproduction? A decision analysis of treatment costs in male infertility. J. Urol. 174: 1926, 2005, PMID ... In the USA, about 2% of men later go on to have a vasectomy reversal afterwards. However the number of men inquiring about ... of men are satisfied with having had the procedure. While there are a number of reasons that men seek a vasectomy reversal, ...
"Infertility in men". Retrieved 2007-11-21. Costabile RA, Spevak M (2001). "Characterization of patients presenting with male ... The use of carnitine showed some promise in a controlled trial in selected cases of male infertility improving sperm quality ... Conception device Male infertility Semen quality Vasectomy thefreedictionary.com > oligospermia Citing: Dorland's Medical ... Check JH (2007). "Treatment of male infertility". Clin Exp Obstet Gynecol. 34 (4): 201-6. PMID 18225678. Adamopoulos DA, ...
... has been used to prevent the testosterone flare at the initiation of GnRH agonist therapy in men with prostate ... Wheeler CJ, Keye WR, Peterson CM (2010). "Polycystic Ovary Syndrome". Reproductive Endocrinology and Infertility. pp. 147-182. ... Oral ketoconazole has been used clinically as a steroidogenesis inhibitor in men, women, and children at dosages of 200 to ... Ketoconazole has additionally been used, in lower dosages, to treat hirsutism and, in combination with a GnRH analogue, male- ...
ISBN 0-632-03906-X. S. Lee (2003). "Myths and reality in male infertility". In J. Haynes; amp; J. Miller (eds.). Inconceivable ... His book Counselling in Male Infertility was published in 1996; he contributed to major newspaper articles and appeared on ... S Lee (1996). Counselling in male infertility. Oxford: Blackwell Scientific Press. ... such as Counselling in Male Infertility, and was also a contributor/consultant in such books: The Miraculous World of The ...
"Mitochondria-related male infertility." Proceedings of the National Academy of Sciences 103.41 (2006): 15148-15153. Labuda, ... Males are more susceptible to mtDNA defects, not only because of lack of selection for mtDNA on males but also due to sperm's ... Mother's curse predicts that mtDNA mutations pose a greater threat on males and male-specific detrimental mutations in mtDNA ... Because of maternal inheritance, mtDNA has no selection in males. Instead, mutations only deleterious to males could be ...
Vaclav Insler; Bruno Lunenfeld (January 1993). Infertility: Male and Female. Churchill Livingstone. p. 458. ISBN 978-0-443- ... In men, cyclofenil can increase testosterone levels due its progonadotropic effects. In terms of distribution, cyclofenil acts ... It has been used as a doping agent by male athletes. Cyclofenil is used to treat menstrual disturbances and anovulatory ... Cyclofenil has been used by male athletes to increase testosterone levels. It is not effective for this purpose in women. ...
Varicocele and Male Infertility: A Complete Guide. Medical Textbooks. Springer. 2019. ISBN 9783319791012. Male Infertility: ... Medical and Surgical Management of Male Infertility. ISBN 978-9350259467. "Understanding Male Infertility Global practices and ... Andrological Evaluation of Male Infertility: A Laboratory Guide. Springer. 2016. ISBN 9783319267951. Male Infertility for the ... Varicocele and Male Infertility: Asian Journal of Andrology, Volume 18, Number 2, March 2016. The Azoospermic Male: Current ...
"Teratozoospermia and male infertility". Forum Instituto Bernabeu. 2016-11-25. Retrieved 2019-05-06.. ...
Durairajanayagam D, Agarwal A, Ong C, Prashast P (March 2014). "Lycopene and male infertility". Asian Journal of Andrology ( ... It has also been used to investigate the effects of lycopene on heart function and male fertility. A study at the Cleveland ... Karppi J, Laukkanen JA, Sivenius J, Ronkainen K, Kurl S (October 2012). "Serum lycopene decreases the risk of stroke in men". ... Karppi J, Laukkanen JA, Sivenius J, Ronkainen K, Kurl S (September 2009). "Serum lycopene decreases the risk of stroke in men ...
WHI&FC (17 November 2020). "Causes of Male Infertility". Kampala: Women's Hospital International and Fertility Centre (WHI&FC ... Investigation of infertility in men and women WHI&FC maintains a subsidiary clinic in Kigali, Rwanda, known as Kigali IVF and ... WHI&FC (17 November 2020). "Causes of Female Infertility". Kampala: Women's Hospital International and Fertility Centre (WHI&FC ...
20 October 2010). Male Infertility: Problems and Solutions. Springer Science & Business Media. pp. 83-. ISBN 978-1-60761-193-6. ... Gynecomastia has been reported in males treated with domperidone,[37] and galactorrhea could occur in males as well.[36] ... much greater in women than in men.[60][61] This appears to be due to the higher estrogen levels in women, as estrogen ... male patients may experience low libido, erectile dysfunction, and impaired spermatogenesis.[36] Also in accordance with ...
Raman JD, Schlegel PN (February 2002). "Aromatase inhibitors for male infertility". The Journal of Urology. 167 (2 Pt 1): 624-9 ... Male reproductive system[edit]. The effect of estradiol (and estrogens in general) upon male reproduction is complex. Estradiol ... Though estradiol levels in men are much lower compared to those in women, estradiol has important roles in men as well. Apart ... Smaller amounts of estradiol are also produced by the adrenal cortex, and, in men, by the testes.[medical citation needed] ...
In men, her research team and collaborators have investigated mechanisms of male infertility. In a study published in 2000, she ... There, she worked in the laboratory of David C. Page, where she worked to map genes linked to male infertility on the Y ... Her research group has also worked on developing alternative solutions for men experiencing infertility through an ... neurodegenerative diseases such as Parkinson's disease and also infertility in men and women. Reijo Pera grew up in Iron River ...
"Infertility - Treatment". nhs.uk. 2017-10-23. Retrieved 2019-09-24. Liu, Wen; Schulster, Michael L.; Alukal, Joseph P.; Najari ... Klami, Rauni; Mankonen, Harri; Perheentupa, Antti (2018). "Successful microdissection testicular sperm extraction for men with ... where infertility is caused by a lack of sperm production rather than a blockage. In these cases, micro-TESE is more likely to ... Bobby B. (2019-08-16). "Fertility Preservation in Male to Female Transgender Patients". Urologic Clinics of North America. 46 ( ...
20 October 2010). Male Infertility: Problems and Solutions. Springer Science & Business Media. pp. 83-. ISBN 978-1-60761-193-6 ... Anisogamy Evolution of sexual reproduction Folliculogenesis Germ cells Male infertility Meiosis Oncofertility Oogenesis Origin ... Spermatozoa are the mature male gametes in many sexually reproducing organisms. Thus, spermatogenesis is the male version of ... see Male infertility). Spermatogenesis starts in the bottom part of seminiferous tubes and, progressively, cells go deeper into ...
He is the author of Surgery of Male Infertility, the first textbook on the subject. He co-edited the updated edition Surgical ... Abdel-Meguid TA; Al-Sayyad A; Tayib A; Farsi HM (2011). "Does varicocele repair improve male infertility? An evidence-based ... Goldstein is a specialist in male infertility and scrotal disorders and is internationally renowned for his pioneering work on ... Goldstein has been at the forefront of male infertility surgical innovation. He holds patents for the Goldstein Microspike ...
... infertility, and gynecomastia. Because men have no reliable indicator such as menstruation to signal a problem, many men with ... Sabanegh ES (20 October 2010). Male Infertility: Problems and Solutions. Springer Science & Business Media. pp. 83-. ISBN 978-1 ... infertility and erectile dysfunction in men. Hyperprolactinaemia can also be a part of normal body changes during pregnancy and ... or irregular menses or infertility, and in men with impaired sexual function and milk secretion. If prolactin is high, a doctor ...
Infertility affects both men and women. At least 97% of men with cystic fibrosis are infertile, but not sterile, and can have ... Chen H, Ruan YC, Xu WM, Chen J, Chan HC (2012). "Regulation of male fertility by CFTR and implications in male infertility". ... Many men found to have congenital absence of the vas deferens during evaluation for infertility have a mild, previously ... Male infertility caused by absence of the vas deferens may be overcome with testicular sperm extraction, collecting sperm cells ...
A man with one remaining testis may maintain fertile. However, sperm banking may be appropriate for men who still plan to have ... Treatment may result in infertility. Risk factors include an undescended testis, family history of the disease, and previous ... The risk of testicular cancer in white men is approximately 4-5 times the risk in black men, and more than three times that of ... It accounts for less than 1% of cancer deaths in men (around 60 men died in 2012). Testicular tumors occur also in animals. In ...
Glezerman M, Jecht E (eds.). Varicocele and Male Infertility II. Springer, Berlin-Heidelberg-New York-Tokyo, 1984. Glezerman M ... "Men are the Weaker Sex, Says Study of Births". The Telegraph. May 27, 2009. "Annaliese Beery (Cohort 6) Haaretz.com". ... Lunenfeld B, Insler V, Glezerman M. Diagnosis and treatment of functional infertility. Completely revised edition. Berliner ...
Lotti, Francesco; Maggi, Mario (2018). "Sexual dysfunction and male infertility". Nature Reviews Urology. 15 (5): 287-307. doi: ... as a condition that affects a large population of American males. It also had reported that, if possible, men would be willing ... there is a large emphasis on male reproductive organs and male fertility. Today, sexual medicine has reached a wider range of ... For example, males have more problems related to function of their reproductive organs, where as for women it is more common to ...
In humans, azoospermia affects about 1% of the male population and may be seen in up to 20% of male infertility situations in ... Azoospermia is the medical condition of a man whose semen contains no sperm. It is associated with infertility, but many forms ... Male Infertility Best Practice Policy Committee of the American Urological Association; Practice Committee of the American ... Dohle, Gert R (2010). "Male infertility in cancer patients: Review of the literature". International Journal of Urology. 17 (4 ...
... is under investigation as a potential male contraceptive and as the first male birth control pill. Antiandrogens such as ... Marc A. Fritz; Leon Speroff (28 March 2012). Clinical Gynecologic Endocrinology and Infertility. Lippincott Williams & Wilkins ... In men, a study found that treatment with a relatively low dosage of 20 μg/day ethinylestradiol for 5 weeks increased ... In males, antiandrogens are used in the treatment of prostate cancer, enlarged prostate, scalp hair loss, overly high sex drive ...
1993). "Primary amenorrhoea and infertility due to a mutation in the beta-subunit of follicle-stimulating hormone". Nat. Genet ... immunoreactivity and hormone receptor mRNA in testicular tissue of infertile men". Cell Tissue Res. 278 (3): 595-600. PMID ...
Male Gray langur monkeys may attack females following male takeover, causing miscarriage.[43] ... "Reproductive Endocrinology and Infertility: Recurrent Pregnancy Loss (Recurrent Miscarriage)." (n.d.) Retrieved 2006-01-18 from ... Usually this is done because males harass pregnant mares or force copulation.[39][40][41] Scientists have raised the question, ... "Further evidence for male infanticide and feticide in captive plains zebra, Equus burchelli". Folia Zool. 54 (3): 258-262 ...
For example, a medicine man would apply herbs and say prayers for healing, or an ancient philosopher and physician would apply ... In many cases these materials were used ritually as magical substances by priests, shamans, or medicine men. Well-known ...
Smoking and male infertility. *Smoking cessation. *Tobacco-Free Pharmacies. *Tobacco packaging warning messages ... Isle of Man[edit]. Smoke-free restrictions came into effect in the Isle of Man on 30 March 2008. ... Prison smoking bans are also in force in New Zealand, the Isle of Man and the Australian states of Victoria, Queensland, ...
Male pubertal development[edit]. At the time of puberty, androgen levels increase dramatically in males, and androgens mediate ... Reduced ability of an XY-karyotype fetus to respond to androgens can result in one of several conditions, including infertility ... In males, certain Y chromosome genes, particularly SRY, control development of the male phenotype, including conversion of the ... To examine neurogenesis, wild-type male rats were compared with male rats that had testicular feminization mutation (TMF), a ...
The men who participate in the sexual exploitation of children at these installations are most often from developed countries ... Physical hazards can also include infertility, cervical cancer, assault, and sometimes murder.[7] Pregnancy is also a physical ... The perpetrators are most often men who try to "rationalize their sexual involvement with children."[9] The vendors are the ... Females are typically exploited for sexual purposes while males are used for labor of all kinds. Women and young girls being ...
An association between male sterility and bronchiectasis". West. J. Med. 144 (6): 744-6. PMC 1306774 . PMID 3727536. ... Infertility Cystic fibrosis Handelsman DJ, Conway AJ, Boylan LM, Turtle JR (January 1984). "Young's syndrome. Obstructive ... doi:10.1136/bmj.326.7382.226/g. Online Mendelian Inheritance in Man (OMIM) Young syndrome -279000 Hendry WF, A'Hern RP, Cole PJ ... Young's syndrome, also known as azoospermia sinopulmonary infections, sinusitis-infertility syndrome and Barry-Perkins-Young ...
In malesEdit. Prostate cancerEdit. See also: Management of prostate cancer § Hormonal therapy, and Androgen deprivation therapy ... Marc A. Fritz; Leon Speroff (28 March 2012). Clinical Gynecologic Endocrinology and Infertility. Lippincott Williams & Wilkins ... Androgens increase sex drive,[38] and for this reason, antiandrogens are able to reduce sex drive in men.[39][40] In accordance ... In males, antiandrogens are used in the treatment of prostate cancer, enlarged prostate, scalp hair loss, overly high sex drive ...
However, killing another male's cubs, upon the takeover, allows the new selected gene complement of the incoming alpha male to ... His inbreeding coefficient was 0.254, equivalent to the offspring of brother-sister incest.[85] His impotence/infertility led ... In lions, prides are often followed by related males in bachelor groups. When the dominant male is killed or driven off by one ... If there is more than one dominant male, the group of alpha males are usually related. Two lines are then being "line bred". ...
"Anabolic steroids abuse and male infertility". Basic Clin Androl. 26: 2. doi:10.1186/s12610-016-0029-4. PMC 4744441. PMID ...
"Bdnf DNA methylation modifications in the hippocampus and amygdala of male and female rats exposed to different caregiving ...
For example, the FGR 13 has estimated that the ratio of thyroid cancer incidence for women as compared to men is 2.14, while ... infertility, and other reproductive developmental problems.[23][27][33] ... However, women develop cancer from radiation at a rate from 37.5% to 52% higher than that of men. In recent years, studies ... The BEIR VII Committee concluded that, given the same level of radiation exposure, women are 52 percent more likely than men to ...
Surviving Male Menopause. A Guide for Women and Men. Naperville, Ill: Sourcebooks. 2000. ISBN 1-57071-433-9.. ... 和不育(英语:Reproductive endocrinology and infertility). *下丘脑垂体性腺轴(英语:Hypothalamic-pituitary-gonadal axis) ... 所謂的「男性更年期」(andropause)本身有其爭議性[94]。大眾對於「男性更年期」的關注是源於1998年由心理學家傑德·戴蒙所著的《Male Menopause》[95]。依照戴蒙的觀點,「
Transgender men may experience a higher than expected rate of PCOS due to increased testosterone, if they choose to take ... Molecular progress in infertility: polycystic ovary syndrome. Fertil. Steril. 2002, 78 (3): 569-76. PMID 12215335. doi:10.1016/ ... Balen A. Metformin therapy for the management of infertility in women with polycystic ovary syndrome (PDF). Scientific Advisory ... Serum (blood) levels of androgens (hormones associated with male development), including androstenedione and testosterone may ...
"Stem Cell Therapies for Male Infertility: Where Are We Now and Where Are We Going?". Biennial Review of Infertility. 2015. Bone ...
Medical and gynecological textbooks are also at fault in the way that the clitoris is described in comparison to a male's penis ... "Outcome of Vaginoplasty in Male-to-Female Transgenders: A Systematic Review of Surgical Techniques". The Journal of Sexual ... Rodriguez said that a male's penis created the framework of the sexual organ.[11] ... Reproductive endocrinology and infertility. *Sexual medicine. Disorder. *Disorders of sex development. *Infertility ...
Woywodt A, Matteson EL (October 2006). "Wegener's granulomatosis--probing the untold past of the man behind the eponym". ... of people with GPA but is associated with significant toxicities including infertility, inflammation and bleeding from the ... The prevalence of GPA in the United States is estimated to be 3 cases per 100,000 people and equally affects men and women.[10] ...
As part of the pharmacologic treatment of paraphilic disorders in sexual offenders or men with a high risk of sexual offending[ ... Breast cancer; Endometrial hyperplasia; Endometriosis; Female infertility (assisted reproduction); Prostate cancer; Uterine ... Turner D, Briken P (January 2018). "Treatment of Paraphilic Disorders in Sexual Offenders or Men With a Risk of Sexual ... Generally, long-term patients, both male and female, tend to undergo annual DEXA scans to appraise bone density. ...
0.5%-13% (in uncircumcised males 18 years or older)[7]. Phimosis is a condition in which the foreskin of the penis cannot ... Physiologic phimosis, common in males 10 years of age and younger, is normal, and does not require intervention.[25][32][33] ... A commonly cited incidence statistic for pathological phimosis is 1% of uncircumcised males.[19][30][39] When phimosis is ... The foreskin is usually non-retractable in early childhood, and some males may reach the age of 18 before their foreskin can be ...
Man K.; Damasio A.; Meyer K.; Kaplan J.T. (2015). "Convergent and invariant object representations for sight, sound, and touch" ... Man K, Kaplan J.T., Damasio H, Damasio A. (28 October 2013). "Neural convergence and divergence in the mammalian cerebral ... Reproductive endocrinology and infertility. *Urogynecology. Diagnostic. *Radiology *Interventional radiology. *Nuclear medicine ...
Online Mendelian Inheritance in Man (OMIM) Branchiootorenal Syndrome 1; BOR1 -113650 *^ Smith, Richard JH (1993-01-01). " ...
Operations on the male genital organs 5-65...5-71: Operations on the female genital organs 5-72...5-75: Obstetric surgery 5-76 ... birth Accompanying measures and treatment for infertility 9-31...9-32: Phoniatrics and pedaudiological therapy 9-40...9-41: ...
Infertility. The gonads (ovaries and testicles) are very sensitive to radiation. They may be unable to produce gametes ... In males previously having undergone radiotherapy, there appears to be no increase in genetic defects or congenital ...
Redirected from Human male reproductive system). This article is about the reproductive system in human males. For the male ... Some individuals are male who have the XX male syndrome and androgen insensitivity syndrome. This occurs when one X chromosome ... Wikimedia Commons has media related to Male reproductive system.. *This article incorporates text in the public domain from the ... it will produce and secrete male sex hormones during late embryonic development and cause the secondary sex organs of the male ...
... and slightly less effective than permanent male sterilization through vasectomy.[5] These rates are significantly higher than ... Including vaginal intercourse: Breastfeeding infertility (LAM). *Calendar-based methods (rhythm, etc.). *Fertility awareness ( ... compared to approximately 42.5 million men who have undergone vasectomy.[39] ... such as oral contraceptive pills or male condoms.[6] ...
... reproductive endocrinologists are trained to also test and treat hormonal dysfunctions in females and males outside infertility ... Reproductive endocrinology and infertility (REI) is a surgical subspecialty of obstetrics and gynecology that trains physicians ... In Australia and New Zealand, a training program in reproductive endocrinology and infertility takes 3 years, and is offered in ... In the United States, fellowship in reproductive endocrinology and infertility usually takes 3 years, and is offered in 40 ...
a b Online Mendelian Inheritance in Man (OMIM) Huntington Disease -143100 *^ Nasir J, Floresco SB, O'Kusky JR, Diewert VM, ... Online Mendelian Inheritance in Man (OMIM) 600882 Charcot-Marie-Tooth Disease, Axonal, Type 2B; CMT2B - 600882 ...
Because the men were receiving 40% CR and subject to malnutrition this study was not one of calorie restriction per se.[nb 1] ... infertility), and underweight mothers are more prone to preterm delivery.[21] ... calorie reduction on male college students at the Carnegie Institution for Science.[35] Reduced rations had turned out to be " ... This study was conducted during World War II on a group of lean men, who restricted their calorie intake by 45%[6] for 6 months ...
Male case[edit]. In 1994, a 28-year-old man with EIS was reported.[7][8] He was fully masculinized.[10] At 204 cm, he had tall ... There is complete infertility, which is due both to testicular defects and to severely compromised normal sexual behavior (see ... and male and female αERKO mice are infertile, βERKO males are fertile while females are subfertile, male and female double ... Males[edit]. *LH and testosterone levels are both increased 2-fold due to loss of negative feedback by estradiol on the HPG ...
... among couples are caused by infertile conditions in male nowadays.There are a number of treatment options available for male ... Treating Male Infertility * 1. Treating Male Infertility * 2. Men even suffer from infertility issues just like women. It has ... Male infertility - low sperm count ... by 24x7esubmission O... 710 views * TRUS in Evaluation of Male Infertility by Siewhong ... Treatment Options For Male Infertility Treatments include * 12. Medication, which can treat some issues that affect male ...
How does obesity potentially render men infertile? This new study explores the possible reasons and the various therapies that ... Male factor infertility constitutes 25 to 30% of all cases of infertility and contributes, in combination with female factors, ... Obesity and Male Infertility. A Practical Approach. Ahmad O. Hammoud, M.D., M.P.H.; A. Wayne Meikle, M.D.; Leonardo Oliveira ... Obesity in men is associated with infertility in numerous studies, and the temporal trend for a decline in semen parameters ...
Infertility - Male infertility: The causes of male infertility include problems with sperm production, blockage of the sperm- ... Infertility is also more likely to occur in men born with a low birth weight compared with those born with an average weight ... Evidence suggests that reduced sperm function and male infertility may be risk markers of disease later in life. For instance, ... although a causal link is lacking, male infertility has been ... Male infertility. The causes of male infertility include ...
Read about the causes of male infertility and treatments. ... Infertility is when a woman cant get pregnant after a year or ... Causes of Male Infertility (American Society for Reproductive Medicine) * Sperm release pathway (Medical Encyclopedia) Also in ... Infertility is a term doctors use if a man hasnt been able to get a woman pregnant after at least one year of trying. Causes ... ClinicalTrials.gov: Infertility, Male (National Institutes of Health) * ClinicalTrials.gov: Oligospermia (National Institutes ...
... problem-oriented approach devoted exclusively to the surgery of male infertility. Step-by-step descriptions along with clearly ... Infertility.html?id=vHtsAAAAMAAJ&utm_source=gb-gplus-shareSurgery of Male Infertility. ... infertility inguinal ring injection injury intraoperative laparoscopic layer ligation lumen magnification male infertility ... problem-oriented approach devoted exclusively to the surgery of male infertility. Step-by-step descriptions along with clearly ...
The Male Infertility Program at the Massachusetts General Hospital Fertility Center helps couples conceive by using the least ... Male Infertility Program. The Male Infertility Program at the Massachusetts General Hospital Fertility Center helps couples ... The Male Infertility Program offers the complete range of services for couples struggling with infertility. Our program ... 6 Things You Should Know About Male Infertility Confronting infertility can be scary and stressful, but its helpful to learn ...
Which has been shown to actually reduce a mans sperm count and lead to infertility? We talked with experts in male fertility ... "This is another reason its very important for men to be evaluated by a urologist whos specially trained in male infertility ... "The most common treatable cause of male factor infertility is called varicocele," said Dr. Dan Williams, director of male ... Most men who are obese, he said, have no trouble, although "there is some suggestive evidence that some men with obesity will ...
... young men participating in a small study developed a hormonal condition more typically found in older men. ... Questions around male fertility. The World Health Organization estimates that one in every four couples of reproductive age in ... For the men taking ibuprofen, within 14 days, their luteinizing hormones -- which are secreted by the pituitary gland and ... Ibuprofen has a negative impact on the testicles of young men, a study published Monday in the journal Proceedings of the ...
Vocus) March 23, 2010 -- Infertile men are at nearly three times greater risk for developing clinically significant prostate ... Male infertility, sometimes called male factor infertility, affects about five to 10 percent of reproductive age men. In about ... The analysis identified 168 post-infertility prostate cancers; men with male factor infertility were 2.6 times more likely to ... The Turek Clinic, founded in 2008, is a mens reproductive health practice specializing in male infertility, vasectomy, ...
... they found that mens BMI was a risk factor for infertility in both the older and younger men. ... The majority of men and women were more than 30 years old. Twenty-eight percent of the couples had experienced infertility. ... Researchers found that mens BMI was an independent risk factor for infertility. The researchers adjusted for other factors ... "The data suggest that a 20-pound increase in mens weight may increase the chance of infertility by about 10 percent," says ...
Sensorineural deafness and male infertility is a condition characterized by hearing loss and an inability to father children. ... medlineplus.gov/genetics/condition/sensorineural-deafness-and-male-infertility/ Sensorineural deafness and male infertility. ... Sensorineural deafness and male infertility is caused by a deletion of genetic material. on the long (q) arm of chromosome 15. ... CATSPER-Related Male Infertility. 2009 Dec 3 [updated 2017 Mar 23]. In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, ...
A diagnosis of male infertility typically happens after testing of both partners and finding fertility trouble in the male. ... www.healthymale.org.au/mens-health/male-infertility Out of... ... It can be hard to recognize male infertility. ... It can be hard to recognize male infertility. A diagnosis of male infertility typically happens after testing of both partners ... one couple will experience reproductive problems as a result of male infertility.[2] X Research source Male infertility may ...
... infertility, neuro-urology, pediatric urology, urologic laparoscopy and robotics, urologic oncology, urologic reconstruction, ... Male infertility problems can occur when sperms are limited in number or function. In this paper, we describe the clinical ... Focus Issue on Male Infertility. Hideyuki Kobayashi, Koichi Nagao, and Koichi Nakajima ... Among the possible reasons for male infertility, nonobstructive azoospermia is the least treatable, because few or no mature ...
Patho- physiological mechanisms and etiological factors in male infertility are largely unknown. This has significantly ... Though we accept the treatment of varicocele as the best available treatment of male infertility, we do not know its mechanism ... Sterilität birth evaluation fertility infection infertility inflammation pharmacology physiology production reproduction ... have facilitated the development of different specialities dealing with the problems of infertility. It is now possible in ...
Aspects of Male Infertility. Volume 4 of International Perspectives in Urology, V. 4. I.P.U. Series. ... Infertility.html?id=_TRsAAAAMAAJ&utm_source=gb-gplus-shareAspects of Male Infertility. ... hypothalamic idiopathic immune immunologic impotence increase insemination lesions levels Leydig cells male infertility ... 0 Reviewshttps://books.google.com/books/about/Aspects_of_Male_Infertility.html?id=_TRsAAAAMAAJ ...
The surgical management of male infertility is one of the most exciting topics in all of medicine. Over the last 25 years, the ... We can now offer successful treatment options to thousands of couples affected by male factor infertility whose only options in ... A Cross-Sectional Study on Environmental DDT Exposure and reduced seminal parameters in Men from Chiapas, Mexico ... application of advanced microsurgical techniques has made the treatment of the infertile male one of the great success stories ...
Male Infertility: Contemporary Clinical Approaches, Andrology, ART & Antioxidants offers a comprehensive review of well- ... A ground-breaking contribution to the literature, Male Infertility: Contemporary Clinical Approaches, Andrology, ART & ... Designed as an easily accessible practical reference for daily use, Male Infertility: Contemporary Clinical Approaches, ... Apoptosis Capacitation Hyperactivation Male infertility Nutrition Oxidative stress Sperm chromatin integrity Spermatoza ...
Amy and Todd have been trying to conceive for 2 years. Initially, when they decided to start a family, Todd was certain they would become pregnant very quickly. In his previous marriage, Todd had conceived each of his two children, now 20 and 22 years old, within 3 months. However, on Amys 35th birthday, the couple realized they could no longer explain away their problem and decided to consult a fertility specialist.. ...
Infertility in the Male. 4th Edition. Edited by Larry I. Lipshultz Baylor College of Medicine. Stuart S. Howards University of ... Immunologic infertility Thomas J. Walsh and Paul J. Turek; 17. The effect of genital tract infection and inflammation on male ... Testicular biopsy in male infertility evaluation Joseph P. Alukal, Mohit Khera and Thomas M. Wheeler; 14. Adverse effects of ... Microsurgical treatment of male infertility Edmund S. Sabanegh Jr. and Anthony J. Thomas Jr.; 22. Techniques of sperm retrieval ...
Vitamin D And Male Fertility - Infertility at BellaOnline ... BellaOnlines Infertility Editor. Vitamin D And Male Fertility ... Ann Clark assessed the vitamin D levels of 794 men visiting an infertility clinic in Sydney, and showed that over one third ... The men with vitamin D deficiency were also found to be more likely to be deficient in folic acid - also important for male ... restoring optimal vitamin D levels could have a profound effect upon male-factor infertility.. An Australian study (2) led by ...
... can negatively affect male fertility in overt and subtle ways. - Can Vaping Harm Male Fertility? - Infertility at BellaOnline ... lifestyle and nutritional factors in male infertility. Wright C1, Milne S2, Leeson H3. ... For men who are trying to conceive, it makes sense to give up ANY form of nicotine, and ideally, to become nicotine free for at ... Men who smoke tobacco often consider committing to a program of smoking cessation to improve the chances of conception, but ...
... due to male factors alone, 20% due to a combination of female and male factors, and 15% unexplained. ... Infertility is defined as the inability to achieve pregnancy after one year of unprotected intercourse. An estimated 15% of ... encoded search term (Male Infertility) and Male Infertility What to Read Next on Medscape ... Causes of infertility in men can be categorized as obstructive or nonobstructive. Infertile men may have deficiencies in sperm ...
... antisperm antibodies in males? Anyone tried any successful treatment? ... Is anyone familiar with male factor infertility, or more specifically, ... Is anyone familiar with male factor infertility, or more specifically, antisperm antibodies in males? Anyone tried any ... Men who have had a vasectomy reversal are especially likely to have antisperm antibodies. Almost 70% of men who had this ...
Male reproductive physiology, Diagnosis of Male Infertility, Causes of Male infertility, Treatment of Male infertility, Male ... Male Infertility. April 20.2011. - Paul J. Turek, MD Male Infertility Introduction. Infertility is defined as the inability to ... Male Infertility. Primary infertility affects 15-20% of married couples. Approximately one-third of cases result from male ... The evaluation of male infertility is undertaken methodically to acquire several kinds of information. Male Infertility * ...
Some of the causes of infertility are for men, a sperm disorder. Infertility causes in women can be an ovulation disorder, ... Infertility Quiz: Test Your IQ of Infertility. Learn about the signs and causes of infertility in women and men. Get facts on ... this equals 3.3-4.7 million men. Of men who sought help, 18% were diagnosed with a male-related infertility problem, including ... Both men and women contribute to infertility.. Many couples struggle with infertility and seek help to become pregnant; however ...
hi.im 22 male and i have been working out since i was 15.before that i used to be overweight.that changed dramatically and i ... hi.im 22 male and i have been working out since i was 15.before that i used to be overweight.that changed dramatically and i ... There are some hereditary conditions in which males have elevated estradiol levels. Also some endocrine syndromes. MOST of the ... Many couples are turning to acupuncture to treat infertility. But does it work? We take a closer look. ...
... to male infertility as well as validate its potential as genetic markers for diagnosis and risk assessment for male infertility ... Variations in Antioxidant Genes and Male Infertility. Bolan Yu1,2 and Zhaofeng Huang3,4,5 ... In this review, we discuss the association between variations in major antioxidant genes and male infertility. Numerous studies ... The synergistic effects of environmental ROS and functional polymorphisms on antioxidant genes that result in male infertility ...
... of all infertility cases. This resource covers the causes, treatment and prevention of male infertility. ... Male infertility factors contribute to approximately 30% of all infertility cases, and male infertility alone accounts for ... Can male infertility be prevented?. There is usually nothing that can be done to prevent male infertility caused by genetic ... How is male infertility diagnosed?. Potential male infertility will be assessed as part of a thorough physical examination. The ...
... than men of normal weight, a new study says. ... Men who are overweight weight or obese are more likely to have ... Obese Men at Greater Risk for Infertility. By Karen Rowan 30 May 2013. ... Pass it on: Obese or overweight men are more likely to suffer infertility due to poor sperm counts or lack of viable sperm. ... Men who are overweight or obese are at a greater risk for infertility, a new analysis says. ...
... those with infertility had increased risks for heart disease, diabetes, substance abuse, liver disease, and renal disease. ... Compared with men with vasectomies or receiving fertility tests, ... men with infertility, compared with vasectomized men, had an 81 ... Specifically, compared with the men who received fertility testing, men with infertility had a 30% increased risk for diabetes ... They compared outcomes among 13,027 men diagnosed with male factor infertility (average age, 33 years), with outcomes among ...
  • About 35-40% of the issues among couples are caused by infertile conditions in male nowadays.There are a number of treatment options available for male infertility. (slideshare.net)
  • It has been found out that about 35-40% of the issues among couples are caused by infertile conditions in male and not women. (slideshare.net)
  • Infertility, defined as the absence of pregnancy after 1 year of unprotected intercourse, affects 1 in every 13 couples in the United States. (medscape.com)
  • [ 2 ] In case of presumed male factor infertility, couples are often offered intrauterine inseminations (IUIs) or in vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI). (medscape.com)
  • Happily, many couples treated for infertility are able to have babies. (medlineplus.gov)
  • Part of one of the world's foremost academic medical centers, our program offers the complete range of services for couples struggling with infertility. (massgeneral.org)
  • In his own clinic at the University of Wisconsin, Williams notes, couples are screened together, with the woman seeing an OB/GYN and the man seeing a urologist. (go.com)
  • Couples are evaluated for male and female factor infertility issues simultaneously," he said. (go.com)
  • Fertility really is a couples thing not just a male or a female thing. (go.com)
  • In about 40 percent of all infertile couples, the cause is due to male "factors. (prweb.com)
  • [1] X Research source Out of every five infertile couples, one couple will experience reproductive problems as a result of male infertility. (wikihow.com)
  • We can now offer successful treatment options to thousands of couples affected by male factor infertility whose only options in the past were donor sperm or adoption. (inciid.org)
  • An estimated 15% of couples meet this criterion and are considered infertile, with approximately 35% due to female factors alone, 30% due to male factors alone, 20% due to a combination of female and male factors, and 15% unexplained. (medscape.com)
  • It is believed that antisperm antibodies in the cervical mucus may account for as much as 40% of unexplained infertility in couples. (dailystrength.org)
  • Infertility affects approximately 15% of couples. (health.am)
  • Primary infertility affects 15-20% of married couples. (health.am)
  • Many couples are turning to acupuncture to treat infertility. (medhelp.org)
  • Infertility affects approximately 1 out of every 6 couples . (americanpregnancy.org)
  • Male subfertility is common, and it causes significant duress to couples. (nih.gov)
  • One out of eight couples has trouble conceiving, with nearly a quarter of those cases caused by unexplained male infertility. (news-medical.net)
  • As reported in the issue of the British Medical Journal (BMJ), the study found a strong association between men with infertility problems and the subsequent risk of testicular cancer, with men in couples with fertility problems being over 1.5 times more likely to develop testicular cancer than other men. (medindia.net)
  • Infertility is a condition wherein couples fail to achieve pregnancy or if the woman has been unable to carry a pregnancy that results in a live birth. (medindia.net)
  • Infertility may be treated with medicine, surgery, artificial insemination, or assisted reproductive technology, based on the couples test results and other factors. (medicinenet.com)
  • Surrogacy (the woman's male partner sperm is used to fertilize another woman egg and that other woman carries the fetus to term and the infant is then adopted ) is a way for some couples to obtain a baby. (medicinenet.com)
  • Infertility is a common problem, with more than 5 million couples in the United States dealing with these problems. (clevelandclinic.org)
  • Infertility affects one in every six couples who are trying to conceive. (clevelandclinic.org)
  • The majority of couples suffering from infertility can now be helped to conceive a child on their own. (clevelandclinic.org)
  • The good news is that many cases of male infertility are treatable, allowing couples to achieve their goal of having a family. (clevelandclinic.org)
  • Individuals or couples experiencing any of these feelings are encouraged to seek professional help from a counselor or psychologist experienced in dealing with infertility issues. (clevelandclinic.org)
  • In couples who have not been able to have children, male infertility is the cause in at least half of cases. (eurekalert.org)
  • For this reason, appropriate diagnostic evaluation of infections and inflammation in men should be a component in the basic examination in couples who cannot conceive. (eurekalert.org)
  • Infertility - the failure to conceive after a year of unprotected intercourse - affects one in every six couples worldwide, and the man is implicated in about half of these cases. (eurekalert.org)
  • Infertility is largely thought of as a woman's issue, but male infertility can affect at least one-third of couples who are struggling to conceive. (nytimes.com)
  • In 50% of involuntarily childless couples, a male infertility associated factor is found together with abnormal semen parameters (Dohle 2010). (acupuncture.org.uk)
  • Semen quality of male smokers and nonsmokers in infertile couples. (acupuncture.org.uk)
  • Infertility in men can cause a multitude of problems, not just limited to those couples trying to have a baby. (articleinsider.com)
  • Previous studies have found that infertility affects 15% of couples, but that about 50% of male infertility is potentially correctable. (emaxhealth.com)
  • The research team studied 192 men who were part of couples that were "sub-fertile" - meaning that they had a lower ability to become pregnant than normal, healthy couples. (emaxhealth.com)
  • Antioxidant treatment may play a role in assisting couples with male infertility problems, a new review, published today by the Cochrane Library, suggests. (emaxhealth.com)
  • Because 20%-25% of infertile couples bypass a male evaluation, a lost opportunity to improve men's health should be revisited," they write. (medscape.com)
  • Couples in the UAE in which the male factor is one of multiple factors involved is estimated to be three to four of every 10 cases of infertility as per a 2015 NBCI report. (gulfnews.com)
  • The American Urological Association, Inc.'s (AUA) Male Infertility Best Practice Policy Committee (MIBPPC) in 1998, led by Dr Ira Sharlip, estimated that of the 15 per cent of couples globally who could not conceive a child after one year of regular, unprotected intercourse - 50 per cent was due to a solely female factor, while 20 to 30 per cent were purely male factors. (gulfnews.com)
  • These include sperm extraction procedures and intracytoplasmic sperm injection, a revolutionary technique developed at UCSF that has helped many couples with male fertility problems achieve pregnancy. (ucsfhealth.org)
  • The purpose of this experiment is to test the feasibility of a minimally interventionist protocol for young couples with male factor infertility, which addresses the cause of infertility for these couples which is the inability of the sperm to fertilize the egg.Ultrasound monitoring of natural follicular development utilizing rFSH, GnRH antagonist and rHCG only for the final maturation. (clinicaltrials.gov)
  • Couples with 'pure' male factor infertility of six months or more, defined as not pregnant in spite of being desirous of pregnancy for at least six months with normal sexual activity and no birth control. (clinicaltrials.gov)
  • Infertility is a serious problem estimated to affect 7-26% of all couples globally (1;2). (clinicaltrials.gov)
  • Instead, the vast majority of infertile couples are treated with assisted reproductive techniques (ART) independently of the aetiology (maternal/paternal) causing the infertility (3;5-8). (clinicaltrials.gov)
  • Even though marijuana smoking has not been found in past studies to impact the ability to become pregnant among pregnancy planners in the general population, it may increase the risk of pregnancy loss among couples undergoing infertility treatment. (askmen.com)
  • Infertility affects about 10% of all couples and is defined by a failure to achieve a clinical pregnancy within a year of regular unprotected sexual intercourse. (bioportfolio.com)
  • Infertility affects 48.5 million couples worldwide. (newsweek.com)
  • Given how widespread air pollution is, the authors concluded that how air pollution affects sperm shape and size "may result in a significant number of couples with infertility. (newsweek.com)
  • These couples should consider seeing an infertility specialist for a discussion of their options. (advancedfertility.com)
  • Couples with a male partner's sperm count of less than about 5 million per cc, or the motility below about 30% will most likely need IVF with ICSI in order to conceive. (advancedfertility.com)
  • Couples considering varicocele surgery should see a well trained urologist as well as an infertility specialist for education about all of their options before proceeding. (advancedfertility.com)
  • Twenty-five percent of couples will seek help for infertility at some point during their relationship. (pulsemed.org)
  • Male factor infertility is contributory in at least 50% of infertile couples. (pulsemed.org)
  • Infertility can cause a major setback to the couples due to the inability to conceive.However,modern sciences have come up with spectacular IVF techniques to fulfill their wish.Starting IVF treatment can be an exciting but nerve wracking experience. (a1articles.com)
  • In the growing modern society, infertility concerns about 15-20% couples of the reproductive age and in the Indian scenario, about 15-20 million cases are seen yearly. (bioscience.org)
  • 10-15% of couples are infertile and 40% of those are due to male factors. (films.com)
  • The study, published in the American Journal of Human Genetics, represents an important step in the search for genes that may be responsible for male infertility, which accounts for 30 to 50 percent of the fertility problems faced by couples trying to conceive. (bionews.org.uk)
  • Some infertile couples have more than one factor contributing to their infertility. (sharecare.com)
  • In developed countries, 33% of couples in their late 30s confront infertility problem, as a result of the vocational aspirations and targets they set. (imop.gr)
  • Irrespective of age, it is estimated that about 1 out of 8 couples trying to have a child face some infertility problem, either of a small or great extent. (imop.gr)
  • But infertility affects about 10 percent of couples of childbearing age - and about one third of infertility can be attributed to male factors. (integrisok.com)
  • Roughly half of all fertility problems experienced by couples are a result of male infertility. (amazingpregnancy.com)
  • RxPG] A groundbreaking new test for male infertility, which will save time, money and heartache for couples around the world, has been developed by Northern Ireland's Queen's University Belfast. (rxpgnews.com)
  • By measuring damaged DNA in individual sperm, it can predict the success of infertility treatments and fast-track couples to the treatment most likely to succeed, leading to significantly reduced waiting times and improved chances of conception. (rxpgnews.com)
  • Factors relating to male infertility include: Antisperm antibodies (ASA) have been considered as infertility cause in around 10-30% of infertile couples. (wikipedia.org)
  • There are three important factors to consider when thinking about the interplay between masculinity and infertility: (a) the expectations of men as outlined by the hegemonic masculinity model, (b) expectations for men as they grow up as outlined by society and family, and (c) the psychological effects of infertility on men and subsequently on couples. (goodmenproject.com)
  • What happens to those expectations for couples that are experiencing infertility problems? (goodmenproject.com)
  • The causes of male infertility include problems with sperm production, blockage of the sperm-delivery system, the presence of antibodies against sperm, testicular injury, anatomic abnormalities, and the presence of a varicose vein around the testicle (varicocele)-all of which can affect sperm quality or quantity. (britannica.com)
  • The most common treatable cause of male factor infertility is called varicocele," said Dr. Dan Williams, director of male reproductive medicine and surgery at the University of Wisconsin School of Medicine and Public Health. (go.com)
  • The Turek Clinic, founded in 2008, is a men's reproductive health practice specializing in male infertility, vasectomy, vasectomy reversal, varicocele repair and other minimally invasive procedures using innovative and cutting-edge techniques. (prweb.com)
  • Though we accept the treatment of varicocele as the best available treatment of male infertility, we do not know its mechanism of action and so we cannot predict a therapeutic result. (springer.com)
  • Infertility in men can be due to varicocele, low or absent sperm count, sperm damage or certain diseases. (medicinenet.com)
  • Most men with a varicocele don't show symptoms and are unaware that they have one, though most doctors find them during a physical exam of the testicles (it feels like a bag of worms). (nytimes.com)
  • If your doctor believes a varicocele is the reason for your infertility, a procedure that cuts and ties the enlarged vein can boost your chance of pregnancy success . (nytimes.com)
  • In other words, if a couple will need inseminations with male partner's sperm , or possibly in vitro fertilization anyway, why waste time, money, etc. on surgery for a varicocele. (advancedfertility.com)
  • In our opinion, varicocele surgery is probably not a viable option for men with such low numbers. (advancedfertility.com)
  • Men with counts that are just slightly low (15-20 million) may be more reasonable candidates for varicocele surgery. (advancedfertility.com)
  • The jury is still out on how effective varicocele surgery is as a treatment of male infertility. (advancedfertility.com)
  • Why Varicocele affect male infertility? (a1articles.com)
  • However, once varicocele has caused significant reduction in spermcount (below 5 million per ml), then it is very unlikely that varicocele repair will resolve the male infertility problem. (imop.gr)
  • Risk factors for the formation of antisperm antibodies in men include the breakdown of the blood‑testis barrier, trauma and surgery, orchitis, varicocele, infections, prostatitis, testicular cancer, failure of immunosuppression and unprotected receptive anal or oral sex with men. (wikipedia.org)
  • Testicular biopsy is indicated in azoospermic men with a normal-sized testis and normal findings on hormonal studies to evaluate for ductal obstruction, to further evaluate idiopathic infertility, and to retrieve sperm. (medscape.com)
  • Testicular examination of a man with small testes due to Klinefelter syndrome. (nih.gov)
  • And as you might have guessed, stay off the steroids -- they can cause testicular shrinkage, resulting in infertility. (webmd.com)
  • Researhers from Britain examining the relationship between increasing rates of testicular cancer and decreasing sperm quality, have concluded men who have infertility problems have an increased risk of developing cancer. (medindia.net)
  • Though there are no specific feature was linked to increased risk of testicular cancer, men with poor semen quality overall were between twice and three times as likely to develop testicular cancer. (medindia.net)
  • Men with a low sperm count who had fathered children in the past had a lower risk of developing testicular cancer than men who had been unable to father children at all. (medindia.net)
  • Researchers said the risk remained constant over time, suggesting that sperm abnormalities had been present many years before the diagnosis of cancer, they conclude there may be common risk factors for poor sperm quality and testicular cancer and suggest these factors may be present in the developing male foetus. (medindia.net)
  • To be clear, this grant is not about creating a testicular implant for a man who is missing a real one. (medindia.net)
  • Asymptomatic inflammatory reactions are found in 25% of men who undergo testicular biopsy for infertility. (eurekalert.org)
  • We also offer cryopreservation of male gametes (prior to cancer treatment), testicular tissue and epididymal aspirates. (clevelandclinic.org)
  • Testicular cancer is the most common form of cancer in men and particularly affects men aged between 20 and 35. (medic8.com)
  • Male infertility can be caused by pre-testicular issues, testicular conditions and post-testicular issues. (ochsner.org)
  • In such cases, male infertility is said to have a post-testicular cause. (ochsner.org)
  • We here report the case of a 48,XXYY patient consulting for adult infertility and the indication to perform testicular sperm extraction is discussed. (nih.gov)
  • From a testicular biopsy, it will be possible to obtain spermatozoa that will be cryopreserved until the man wishes to father a child, and then used in ICSI in vitro fertilization. (news-medical.net)
  • However, the utilization of testicular sperm acquisition and IVF appears to be more widely available and will allow men with SCI to achieve parenthood. (sci-info-pages.com)
  • Four of these men were also found to have altered levels of sex hormones , and another had testicular abnormalities, suggesting a link between the mutations and the problems with sperm production. (bionews.org.uk)
  • Skakkebaek, a professor at the department of growth and reproduction at the University of Copenhagen, is a leading authority in the research of testicular cancer and other male reproductive disorders, including low sperm quality. (japantimes.co.jp)
  • Mumps Malaria Testicular cancer Defects in USP26 in some cases Acrosomal defects affecting egg penetration Idiopathic oligospermia - unexplained sperm deficiencies account for 30% of male infertility. (wikipedia.org)
  • Often these earlier studies' methods have been criticised, having been cited for sampling selection bias and the inclusion of men with testicular and fertility issues. (wikipedia.org)
  • Male infertility, sometimes called male factor infertility, affects about five to 10 percent of reproductive age men. (prweb.com)
  • Researchers are working to determine how the loss of additional genes in the deleted region affects people with sensorineural deafness and male infertility. (medlineplus.gov)
  • Men who smoke tobacco often consider committing to a program of smoking cessation to improve the chances of conception, but it's important that they get up-to-speed with how nicotine affects sperm to understand the risks. (bellaonline.com)
  • Since infertility affects one in 25 men these days, maintaining a healthy lifestyle and a positive attitude is the way to go if you're considering becoming a father. (webmd.com)
  • It mainly affects male reproductive function from the following aspects. (selfgrowth.com)
  • Research carried out at the University of Pennsylvania School of Medicine suggests that the packaging of DNA affects the production of sperm and could explain some cases of male infertility. (bionews.org.uk)
  • Male infertility is a problem that affects roughly 7 percent of American men. (lawyersandsettlements.com)
  • It affects approximately 7% of all men. (wikipedia.org)
  • This method is commonly used to overcome various types of male infertility - including low sperm count , abnormal sperm , or sperm that doesn't move well - and was used in about half of IVF treatments using non-frozen embryos in the UK in 2013. (newscientist.com)
  • Infertility treatments can be costly and lengthy. (upmc.com)
  • A limited number of medical treatments are available for improving chances of conception in men with certain causes of infertility. (medscape.com)
  • The breakthrough, reported in the journal The Federation of American Societies for Experimental Biology (FASEB), may lead to greater understanding and control of male fertility, including the development of a male contraceptive 'pill', and treatments for infertility. (bionews.org.uk)
  • Today, there exist no treatments that can improve semen quality of most infertile men. (clinicaltrials.gov)
  • A number of non-surgical and surgical treatments are available to men suffering from infertility. (ochsner.org)
  • Disclaimer Note: While both men and women can be infertile, this article focuses on male infertility, it's most common causes and treatments. (ucsb.edu)
  • If we know more about how spermatogonial stem cells turn into sperm cells, this knowledge could be translated into treatments for men who are unable to produce mature sperm, although this is several years down the line. (rxpgnews.com)
  • Nor is there any solution for adult males living with infertility not addressed by current treatments. (news-medical.net)
  • The reduction of testosterone in the male body normally results in an overall decrease in the production of viable sperm for these individuals thereby forcing them to turn to fertility treatments to father children. (wikipedia.org)
  • When this notion translates into not wanting to participate in infertility treatments, we, as part of a couple experiencing infertility or as a clinician working with said couple, then have a larger problem. (goodmenproject.com)
  • Microsurgical Management of Male Infertility by Jonathan Schiff, M.D. (inciid.org)
  • The surgical management of male infertility is one of the most exciting topics in all of medicine. (inciid.org)
  • Additionally, Aytu is developing MiOXSYS™, a novel, rapid semen analysis system with the potential to become a standard of care for the diagnosis and management of male infertility caused by oxidative stress. (prnewswire.com)
  • Imaging Modalities in the Management of Male Infertility Marcello Cocuzza and Sijo J. Parekattil 4. (buecher.de)
  • Part II: Clinical Management of Male Infertility. (weltbild.de)
  • Papers examining the effects of diet and substance use on male fertility presented at the recently concluded American Society for Reproductive Medicine annual meeting in Honolulu may appear to provide conflicting findings, but an expert in andrology says the observational studies don't tell the complete story. (modernmedicine.com)
  • According to the American Society for Reproductive Medicine, about half of all cases of infertility involve an element of male infertility. (bmc.org)
  • The results of this study will be encouraging to male factor patients and their doctors," Dr. R. Dale McClure, president of the American Society for Reproductive Medicine, said in a society news release. (drugs.com)
  • No evidence-based treatment that increases the likelihood of pregnancy for the infertility associated with male obesity has been demonstrated to date. (medscape.com)
  • Although treatment may not completely restore the quality of semen from men with subnormal fertility, in some cases a successful pregnancy can still be achieved through assisted reproductive technology. (hindawi.com)
  • In a quarter of these men (31) pregnancy was successful. (bellaonline.com)
  • Infertility is defined as the inability to achieve pregnancy after one year of unprotected intercourse. (medscape.com)
  • Zinc and folic acid, a pair of dietary supplements long touted as an effective treatment for male infertility, failed to improve pregnancy rates, sperm counts, and sperm potency in a new study conducted at University of Utah Health and other medical centers in conjunction with the National Institutes of Health. (news-medical.net)
  • Impaired fecundity is a condition related to infertility and refers to women who have difficulty getting pregnant or carrying a pregnancy to term. (medicinenet.com)
  • Feelings of depression, loss, grief, inadequacy and failure are common in men as well as women seeking pregnancy. (clevelandclinic.org)
  • [ 53 ] Tamoxifen is another estrogen-receptor antagonist that, in combination with clomiphene, can increase sperm concentration, sperm motility, and pregnancy rates in males with idiopathic infertility. (medscape.com)
  • By the end of the study, their partner's pregnancy rate was about 37 percent among men who'd taken the combination therapy, compared with 13 percent for those in the placebo group. (drugs.com)
  • Infertile men: men referred to the Scandian Andrology Centre whose infertility is unexplained, whose partners are younger than age 40 and who have had regular sexual intercourse without contraception for at least 12 months without achieving a pregnancy. (clinicaltrials.gov)
  • UCSF is a leader in reproductive health, achieving consistently high pregnancy rates, and we offer a comprehensive array of evaluation and treatment options for men with fertility concerns. (ucsfhealth.org)
  • However, researchers were somewhat shocked to find that male study subjects who copped to currently toking up were more likely to see an uncomplicated pregnancy and successful birth with their partners. (askmen.com)
  • Infertility is defined as the inability to conceive a pregnancy within one year. (pulsemed.org)
  • Infertility is becoming more and more common, in fact over six million American women have difficulty conceiving a child or bringing the pregnancy to term. (a1articles.com)
  • Male infertility refers to a male's inability to cause pregnancy in a fertile female. (wikipedia.org)
  • Varicoceles, a network of abnormally dilated veins in the testes, can have a negative impact on sperm or testosterone production and are the most common cause of male infertility. (massgeneral.org)
  • One cause of male infertility can be the oxidative stress to a male's sperm. (emaxhealth.com)
  • In 1991, he produced the first evidence showing that human sperm counts had fallen by nearly 50 per cent in less than 50 years - low sperm counts are a major cause of male infertility. (independent.ie)
  • Y chromosome deletions Y chromosomal infertility is a direct cause of male infertility due to its effects on sperm production, occurring in 1 out of every 2000 males. (wikipedia.org)
  • Vitamin D - the sunshine vitamin - may be one of the most under-rated male fertility vitamins and one of the most deficient in men trying to conceive. (bellaonline.com)
  • For men who are trying to conceive, it makes sense to give up ANY form of nicotine, and ideally, to become nicotine free for at least three months prior to attempted conception to reduce the risks of producing sperm with hidden DNA fragmentation. (bellaonline.com)
  • Infertility is defined as the inability to conceive after 1 year of unprotected sexual intercourse. (health.am)
  • An infertility diagnosis is given to a couple who are unable to conceive over the course of one year. (americanpregnancy.org)
  • These tips are helpful for any couple trying to conceive, whether or not infertility has been diagnosed. (webmd.com)
  • In general, infertility is defined as not being able to get pregnant (conceive) after one year of unprotected sex. (medicinenet.com)
  • This means that about 10% of all men in the United States who are attempting to conceive suffer from infertility. (clevelandclinic.org)
  • Besides the inability to conceive children, there are many other issues that accompany male infertility. (clevelandclinic.org)
  • If the physical examination and history do not indicate any reason for the couple's inability to conceive, the next step is to conduct testing to identify the cause of infertility. (clevelandclinic.org)
  • The clinical definition of male infertility is the presence of abnormal semen parameters in the male partner of a couple who have been unable to conceive after 1 year of unprotected intercourse (Dohle 2010). (acupuncture.org.uk)
  • Many times infertility is not caused solely by an inability to conceive. (articleinsider.com)
  • When a couple tries to conceive for at least 1 year having regular sexual intercourse without taking any protection, but still there is no successful conception, then it is considered that the couple faces a problem of infertility. (imop.gr)
  • If you are having trouble trying to conceive, it is important for the man to provide the physician a complete health history, particularly including use of medications, drugs, alcohol, caffeine, cigarette smoking and exposure to chemicals or heavy metals. (amazingpregnancy.com)
  • Male and female patients can receive all fertility-related care-coordinated by physicians from the Department of Urology and the Fertility Center-in the convenience of one location. (massgeneral.org)
  • A study from the State University of New York at Stony Brook was published in the Journal of Urology in 1998 where 97 men with infertility were examined to see if their underwear choice made a difference. (go.com)
  • In the experience of Martin Miner, MD, and Joel Heidelbaugh, MD, men's health is far more than the working relationship between urology and primary care centered around male-specific medical concerns, and includes several different and significant subspecialties. (modernmedicine.com)
  • The results suggest that male factor infertility has more than just reproductive implications," write Michael Eisenberg, MD, assistant professor of urology and director of male reproductive medicine and surgery at Stanford University School of Medicine in California, and colleagues. (medscape.com)
  • The study also identified abnormal semen parameters 10 years before cancers were diagnosed, suggesting that early prostate cancer screening is warranted in men with male factor infertility. (prweb.com)
  • Male infertility usually occurs because of sperm that is abnormal, because of inadequate numbers of sperm, or problems with ejaculation. (americanpregnancy.org)
  • The next step is to reproduce the technique in humans as the technology will give new hope to men with low sperm counts or abnormal sperm. (foxnews.com)
  • However, in such men, semen analysis reveals a decreased number of spermatozoa (oligozoospermia), decreased sperm motility (asthenozoospermia) and many abnormal forms of sperm (teratozoospermia) (Dohle 2010). (acupuncture.org.uk)
  • Male infertility is usually defined by abnormal results on semen analysis. (gulfnews.com)
  • For the man, an abnormal sperm exam. (clinicaltrials.gov)
  • The signs and symptoms of sensorineural deafness and male infertility are related to the loss of multiple genes in this region. (medlineplus.gov)
  • The parents of an individual with sensorineural deafness and male infertility each carry one copy of the chromosome 15 deletion, but they do not show symptoms of the condition. (medlineplus.gov)
  • [4] X Research source In this sense, it is difficult to recognize the physical symptoms of male infertility. (wikihow.com)
  • What are the symptoms of male infertility? (clevelandclinic.org)
  • Symptoms of infertility can sometimes be caused by prescription and over the counter medications. (articleinsider.com)
  • Usually affected men show no sign of symptoms other than at times can exhibit smaller teste size. (wikipedia.org)
  • In at least half of all cases of infertility, a male factor is a major or contributing cause. (clevelandclinic.org)
  • Male factor infertility plays a role in about approximately half of all cases of infertility. (fertilityauthority.com)
  • Ochsner is home to an experienced team that can diagnose and treat all aspects of male infertility, both simple and complex. (ochsner.org)
  • In some cases, male infertility is caused by complete absence of spermatozoa in the ejaculate, a condition known as azoospermia. (britannica.com)
  • Among the possible reasons for male infertility, nonobstructive azoospermia is the least treatable, because few or no mature sperm may be produced. (hindawi.com)
  • In many cases, men with nonobstructive azoospermia typically have small-volume testes and elevated FSH. (hindawi.com)
  • Male infertility can be related to a man's inability to produce sperm cells, known in medical terms as azoospermia . (clevelandclinic.org)
  • 48,XXYY men with azoospermia: how to manage infertility? (nih.gov)
  • Over 120,000 men live with non-obstructive azoospermia. (news-medical.net)
  • Men with this condition can exhibit azoospermia (no sperm production), oligozoospermia (small number of sperm production), or they will produce abnormally shaped sperm (teratozoospermia). (wikipedia.org)
  • In vitro fertilization is another option that can be used to overcome male infertility factors. (americanpregnancy.org)
  • Learn how In Vitro Fertilization is used to overcome couple infertility. (films.com)
  • She has previously spent 15 years as the Medical Director of Colorado Center for Reproductive Medicine (CCRM) and has also worked as the Director of the Reproductive Endocrinology and Infertility at Kaiser Oakland. (wikihow.com)
  • The new edition of this canonical text on male reproductive medicine will cement the book's market-leading position. (cambridge.org)
  • While several recent books provide targeted 'cookbooks' for those in a male reproductive laboratory, or quick reference for practising generalists, the modern, comprehensive reference providing both a background for male reproductive medicine as well as clinical practice information based on that foundation has been lacking until now. (cambridge.org)
  • Well, Melanie, it's a great question, and I think it's important to recognize that those of us in reproductive medicine don't see it as either a male or a female issue. (bmc.org)
  • In fact, said Dr. Marc Goldstein, M.D., director of the Center for Male Reproductive Medicine and Microsurgery at the New York-Presbyterian Hospital/Weill Cornell Medical Center, most men who struggle with infertility have completely normal sexual functioning. (nytimes.com)
  • As Aytu continues to garner interest among European reproductive medicine experts, it was important to align with strategic distributors who understand the European infertility market. (prnewswire.com)
  • This concise, truncated version of Parekattil and Agarwal's Male Infertility: Contemporary Clinical Approaches, Andrology, ART & Antioxidants contains all of the need-to-know information about these cutting-edge topics in reproductive medicine. (weltbild.de)
  • Practical for clinicians and researchers alike, Male Infertility for the Clinician contains all of the need-to-know information about these cutting-edge topics in reproductive medicine. (weltbild.de)
  • The loss of another gene, CATSPER2 , in the same region of chromosome 15 is responsible for the sperm abnormalities and infertility in affected males. (medlineplus.gov)
  • During the physical exam, the doctor will look for varicoceles and any abnormalities that might cause infertility. (upmc.com)
  • The World Health Organization defines male factor infertility as the presence of one or more abnormalities in the semen analysis, or the presence of inadequate sexual or ejaculatory function (Rowe 2004). (acupuncture.org.uk)
  • New research published in the journal Environmental Health Perspectives has linked PCBs and other environmental chemicals to sperm abnormalities and male infertility. (emaxhealth.com)
  • All men have a certain number of sperm with such abnormalities, but those with higher levels of PCBs and DDE had significantly higher rates. (emaxhealth.com)
  • Anatomical Abnormalities: Obstructions of the genital tract can cause infertility by partially or totally blocking the flow of seminal fluid. (integrisok.com)
  • These are performed to determine the cause of sperm abnormalities or diseases of the male reproductive system. (integrisok.com)
  • Researchers found an average difference of less than half of a degree Fahrenheit in temperature of the scrotum between men who wore one underwear type or the other, with a margin of error larger than the difference. (go.com)
  • The researchers analysed the sperm quality of semen samples taken from over 32,000 men in England between 1960 and 1989. (medindia.net)
  • The researchers studied DNA from 108 infertile men, and also from their parents. (eurekalert.org)
  • The men in the treatment group also had a greater increase in sperm concentration and an improvement in sperm progression, the Cairo University researchers found. (drugs.com)
  • Researchers say they have found DNA alterations can predict alterations in genes for men with metastatic forms of the disease. (emaxhealth.com)
  • Compared with men of normal weight, overweight and obese men were more likely to have low sperm count, or not have any viable sperm, researchers in France found. (livescience.com)
  • Importantly, the researchers excluded all men diagnosed with underlying conditions at least 1 year before and 1 year after their fertility test or vasectomy, thereby reducing the likelihood of reverse causality because the men were healthy at baseline. (medscape.com)
  • Researchers from Johns Hopkins University, USA, have found a link between female infertility and genetic variation in a gene regulating cholesterol uptake. (bionews.org.uk)
  • Published in the Proceedings of the National Academy of Sciences (NAC), the researchers found that regular use of ibuprofen may lead to compensated hypogonadism, a condition that can cause infertility, erectile dysfunction, depression and loss of bone and muscle mass, among other medical conditions. (lawyersandsettlements.com)
  • The collateral damage of overweight and obesity (a BMI above 25 and 30, respectively) should concern men who fall within that range and wish to continue having children, the researchers argue. (co.ke)
  • A team of researchers, led by Xiang Qian Lao of the Jockey Club School of Public Health and Primary Care at the Chinese University of Hong Kong, examined 6,475 men aged 15 to 49 years. (newsweek.com)
  • The researchers found that seven of the effected individuals had mutations in this gene, while no mutations were found in a control group of 729 men who had normal sperm production. (bionews.org.uk)
  • Boys conceived through IVF tend to have short fingers - a trait linked to infertility, say researchers in a study published in the journal of Reproductive Biomedicine Online. (bionews.org.uk)
  • O ne in three "non-toxic" chemicals used in the manufacture of everyday items significantly affected the potency of sperm cells, which may account for the high incidence of unexplained infertility in the human population, the researchers said. (independent.ie)
  • In a 2013 paper published in the journal BMJ Open, Iwamoto and co-researchers, with the guidance of Skakkebaek, studied the semen quality of 1,559 young men in four cities - Kawasaki, Osaka and Kanazawa and Nagasaki. (japantimes.co.jp)
  • Moreover, the researchers also confirmed that infertile male mice were found to have lower levels of CDO that ruptured the shape and overall health of sperm cells . (naturalnews.com)
  • The researchers concluded that CDO, a critical enzyme in taurine synthesis, is a pivotal mechanism in male fertility . (naturalnews.com)
  • While genetics plays a role in male infertility, other factors may also interfere, he says. (newscientist.com)
  • Until now, their role in male infertility had not been studied. (eurekalert.org)
  • We were surprised to find so many de novo mutations with a potential role in male infertility, given the fact that in previous years only a few novel genes have been discovered in this condition. (eurekalert.org)
  • To help you understand the factors that can contribute to male infertility - and what to do if you're diagnosed - I reviewed the latest scientific research on the topic and spoke to two male-fertility specialists, one ob-gyn, one infertility advocate and two men who have gone through male infertility themselves. (nytimes.com)
  • New data from a study published early in January, 2018, show that regularly taking the common over-the-counter painkiller ibuprofen, may contribute to male infertility. (lawyersandsettlements.com)
  • The tablet won't resolve the eye strain, or carpal tunnel issues per se, but the cool, silent, lightweight device can meet almost all of the standard needs typically met by a laptop, and eliminate the risk of infertility, hearing loss, and back pain at the same time. (pcworld.com)
  • A study has found that men with more kilos than necessary are at greater risk of infertility. (co.ke)
  • Men with more kilos than necessary are at greater risk of infertility, shows a study that also says they could suffer low sperm count and poor quality seed, the precursor to infertility. (co.ke)
  • This spectrum of expression of hypogonadism among obese men originates from multiple interacting factors including reduced levels of gonadotropins and testosterone, altered androgen-to-estrogen ratios, insulin resistance, and sleep apnea. (medscape.com)
  • Older men produce fewer and less-motile sperm, and advancing age is associated with a drop in circulating testosterone levels, as well as a decrease in the overall functioning of the testicles. (britannica.com)
  • For the many men diagnosed with testosterone deficiency, losing weight can help increase testosterone levels. (news-medical.net)
  • Male fertility requires normal sperm production and sperm transport, and adequate sexual performance, functions that require normal levels of testosterone. (acupuncture.org.uk)
  • Testosterone is a hormone found in both males and females although women tend to have much lower levels. (emaxhealth.com)
  • Testosterone imbalances can affect both men and women physically and emotionally and certain foods can help with these imbalances. (emaxhealth.com)
  • The link might be explained by the fact that fat tissue can convert male hormones such as testosterone into the female hormone estrogen, Czernichow said. (livescience.com)
  • Another possibility relates to low levels of testosterone in men with infertility, they note. (medscape.com)
  • In men, LH primarily stimulates testosterone production, while FSH stimulates the production of sperm. (ucsfhealth.org)
  • A bone cell hormone can regulate male fertility hormone testosterone, a study on mice has found. (bionews.org.uk)
  • Resulting in males having smaller testes, reducing the amount of testosterone and sperm production. (wikipedia.org)
  • Tobias S. Köhler, MD, MPH, presents the take home messages on infertility/andrology from the AUA annual meeting in Orlando, FL. (modernmedicine.com)
  • This one-year program (minimum) focuses on the development of clinical excellence in all aspects of male fertility management and basic science techniques in andrology. (clevelandclinic.org)
  • Our new, state-of-the-art Andrology Center offers evaluation, preservation and other services for male fertility. (clevelandclinic.org)
  • A ground-breaking contribution to the literature, Male Infertility: Contemporary Clinical Approaches, Andrology, ART & Antioxidants offers a comprehensive review of well-established, current diagnostic and treatment techniques for male infertility. (buecher.de)
  • Designed as an easily accessible practical reference for daily use, Male Infertility: Contemporary Clinical Approaches, Andrology, ART & Antioxidants provides a high quality guide for urologists, reproductive endocrinologists, embryologists, andrologists, biologists and research scientists interested in the role that antioxidants play in male infertility. (buecher.de)
  • This concise, truncated version of Parekattil and Agarwal's Male Infertility: Contemporary Clinical Approaches, Andrology, ART & Antioxidants is the first resource dedicated solely to clinical issues of infertility. (weltbild.de)
  • Sperm DNA damage caused by oxidative stress: modifiable clinical, lifestyle and nutritional factors in male infertility. (bellaonline.com)
  • Oxidative stress and reactive oxygen species (ROS) are generated from both endogenous and environmental resources, which in turn may cause defective spermatogenesis and male infertility. (hindawi.com)
  • MiOXSYS is the company's in vitro diagnostic platform for assessing the level of oxidative stress in semen as an aid in the diagnosis of infertility in men. (prnewswire.com)
  • Because hypogonadism is a risk factor for cardiovascular disease and mortality, such an explanation may link infertility to cardiovascular disease," they write. (medscape.com)
  • In addition to infertility management, the fellowship will include weekly experiences in a variety of men's health evaluations and procedures to include medical and surgical management of erectile dysfunction, Peyronie's disease, prostatitis syndromes, hypogonadism, and orchialgia. (clevelandclinic.org)
  • The study revealed that several factors could explain the effects of obesity on sperm functions and male subfertility - including the excessive conversion of androgens into oestrogens in redundant adipose tissue causing sexual hormone imbalance, subsequently resulting in hypogonadism. (co.ke)
  • In men, CD can reduce semen quality and cause immature secondary sex characteristics, hypogonadism and hyperprolactinaemia, which causes impotence and loss of libido. (wikipedia.org)
  • Roughly 40% of cases involve a male contribution or factor, 40% involve a female factor, and the remainder involve both sexes. (health.am)
  • Approximately one-third of cases result from male factors, one-third from female factors, and one-third from combined factors. (health.am)
  • Male infertility is solely responsible for 20-30 percent of infertility cases and is a contributing cause, along with a female factor, in another 20-30 percent of cases. (bmc.org)
  • Male infertility factors contribute to approximately 30% of all infertility cases , and male infertility alone accounts for approximately one-fifth of all infertility cases. (americanpregnancy.org)
  • Much research remains to be performed on the topic of male infertility, as many cases still receive an "unknown cause" diagnosis. (americanpregnancy.org)
  • Despite the known importance of genetic factors in the event of the man producing no sperm, only about 25% of these cases can be explained currently. (eurekalert.org)
  • And while infertility is still largely thought of as a woman's issue, the male partner plays a role in at least one-third of cases. (nytimes.com)
  • In the majority of cases of male infertility and low sperm quality, no clear cause can be identified with current diagnostic methods. (bionity.com)
  • Anywhere from 30% to 80% of infertility cases can be due to this factor. (emaxhealth.com)
  • HMG + HCG is not better than placebo in cases of infertility with normal levels of gonadotrophins (Knuth, JCEM 65:1081,1987). (gfmer.ch)
  • However, the truth of the matter is that of the approximately 150,000 cases of infertility in the UAE, approximately 30 per cent are cases related solely to male infertility, going by reports released by various fertility clinics in the region. (gulfnews.com)
  • This is a significantly higher rate of incidence of male infertility than the global average of one in every two cases. (gulfnews.com)
  • Dr Kirnesh Pandey, India's leading diabetes, thyroid and obesity specialist based in Bombay Hospital in Indore, shares one of his experiences from the two to three cases of male infertility he comes across daily. (gulfnews.com)
  • Impaired semen quality is the causal or contributing factor in almost 50% of all cases of infertility (3;4). (clinicaltrials.gov)
  • About 25% of all infertility is caused by a sperm defect and 40-50% of infertility cases have a sperm defect as the main cause, or a contributing cause. (advancedfertility.com)
  • a condition in which a man does not have any measurable level of sperm in his semen and contributes to 5% of infertility cases. (ucsb.edu)
  • In almost half the cases of subfertility, there is a male contribution to the problem. (womens-health.co.uk)
  • About one-third of these cases involve male infertility ( 3 , 4 , 5 ). (bioscience.org)
  • A study has shown that mutations in the NR5A1 gene may be responsible for many unexplained cases of male infertility. (bionews.org.uk)
  • In 30-40% of these cases, the problem is due only to the male factor (male infertility). (imop.gr)
  • It occurs in 20% of men and is responsible for 40% of male infertility cases by affecting sperm quality in many ways: reducing the total spermcount, restricting sperm motility, affecting sperm morphology and impairing the DNA of the sperm. (imop.gr)
  • In some cases, these chemicals are thought to mimic female sex hormones - oestrogens - and in other cases act as anti-androgens, the male sex hormones, thereby interfering with the male reproductive system. (independent.ie)
  • In 60% of cases a male factor is associated or is the main infertility factor. (clinicaltrials.gov)
  • The long-term potential significance of our laboratory findings is the possibility that some cases of male infertility may be caused by inherited mutations in MitoPLD, the signaling enzyme, especially since at least one inactivating mutation is found in the database of sequenced human DNA," Frohman says. (futurity.org)
  • There have been documented cases of sexually active men and women that can develop "sperm antibodies" that can impair sperm functions. (amazingpregnancy.com)
  • 4 According to a study conducted in India, the FOKL VDR gene's restriction fragment length polymorphism was found to be higher in male factor infertility cases as compared to controls. (thefreelibrary.com)
  • Through the collected evidence, we conclude that Vitamin D receptor polymorphism might play a major role in male factor infertility either directly or indirectly by reducing the effects of Vitamin D. Therefore, the role of Vitamin D receptor polymorphism must be thoroughly investigated to see its role in male factor infertility cases of Pakistan. (thefreelibrary.com)
  • In 40 percent of cases, the problems are related to the man. (rxpgnews.com)
  • Genetics Chromosomal anomalies and genetic mutations account for nearly 10-15% of all male infertility cases. (wikipedia.org)
  • It is present in up to 35% of cases of primary infertility and 69-81% of secondary infertility. (wikipedia.org)
  • In addition to impaired semen quality, fertility among obese men may be affected by decreased libido and erectile dysfunction. (medscape.com)
  • Antioxidant supplements do not improve semen quality among men with infertility, according to a new study supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, part of the National Institutes of Health. (news-medical.net)
  • To determine the significance of systemic RANKL inhibition for male reproduction, conducting a clinical controlled randomized double blinded intervention study on infertile men, to investigating whether Denosumab (Prolia) can increase semen quality and to investigate what subgroup of infertile men that might benefit from treatment. (clinicaltrials.gov)
  • To determine the significance of systemic RANKL inhibition for male reproduction by investigating whether Denosumab (Prolia) can increase semen quality and particularly to identify the group of men that will benefit from the treatment. (clinicaltrials.gov)
  • Male infertility is commonly due to deficiencies in the semen, and semen quality is used as a surrogate measure of male fecundity. (wikipedia.org)
  • Beginning in the 1970s and 1980s, the first studies were published that observed declines in the semen quality and later, sperm quantities of men. (wikipedia.org)
  • Artificial Insemination is a medical procedure usually used to treat infertility. (medindia.net)
  • Dr Turek said that while using stem cells to treat infertility among animals has been done, it is yet to be tested in humans. (medindia.net)
  • There are multiple medicines that may be used to treat infertility in women. (medicinenet.com)
  • In this paper, we describe the clinical evaluation of male infertility. (hindawi.com)
  • Large cohort and multiple center-based population studies to identify new antioxidant genetic variants that increase susceptibility to male infertility as well as validate its potential as genetic markers for diagnosis and risk assessment for male infertility for precise clinical approaches are warranted. (hindawi.com)
  • Although infertility may be a marker of diminished fitness, which may accelerate the development of impaired health in the future, it may also occur as a consequence of current health, clinical or subclinical. (medscape.com)
  • Cleveland Clinic is one of the first institutions in the United States to offer a clinical fellowship in Male Infertility. (clevelandclinic.org)
  • The clinical fellow will spend the majority of his/her time in the clinic and in the operating room, evaluating and managing patients with infertility problems. (clevelandclinic.org)
  • Prolia has in several clinical studies shown to be safe and is approved as treatment for osteoporosis in both men and women (21-24). (clinicaltrials.gov)
  • Part I: Clinical Diagnosis of Male Infertility. (weltbild.de)
  • When investigating male infertility, highly crucial is the role of a detailed medical history and thorough clinical examination. (imop.gr)
  • Male Infertility ongoing clinical trials report provides comprehensive analysis and trends in global Male Infertility disease clinical trials. (reportlinker.com)
  • The research work analyzes the ongoing Male Infertility clinical trial trends across countries and companies. (reportlinker.com)
  • The report focuses on drugs and therapies being evaluated for Male Infertility treatment in active clinical development phases including phase 1, phase 2, phase 3 and phase 4 clinical trials. (reportlinker.com)
  • Further, data is presented in user friendly manner to enable readers quick access to Male Infertility clinical trials. (reportlinker.com)
  • However, its clinical value in predicting male fertility or success with infertility treatment is limited, particularly if the semen analysis results are normal,' he added. (rxpgnews.com)
  • Our data extended the role of 1,25(OH)2D3 beyond its conventional physiological actions, paving the way for novel therapeutic opportunities in the treatment of the male reproduction disorders. (bellaonline.com)
  • Compared to reproductive specialists, endocrinologists may see a population of men that have a higher prevalence of treatable causes of subfertility including sexual disorders, endocrinopathies, obesity, drugs, and ejaculatory dysfunction. (nih.gov)
  • In addition to physiological reasons, long-term mental stress and psychological burden can also lead to male endocrine hormone disorders, leading to the death of germ cells and sperm, leading to infertility. (selfgrowth.com)
  • Disorders in the testes can also cause infertility. (ochsner.org)
  • Disorders of both the male and female reproductive systems cause infertility with almost equal frequency. (sharecare.com)
  • Sperm Disorders: Problems with the production and maturation of sperm are the most common causes of male infertility. (integrisok.com)
  • Liver or kidney disease, or treatment for seizure disorders are examples of problems that can cause infertility. (ahealthyme.com)
  • In addition, ultrasound, karyotyping, and hormonal studies are needed to determine specific causes of infertility. (hindawi.com)
  • Polycystic ovarian syndrome is the most common hormonal disorder among women of reproductive age and can cause infertility. (medindia.net)
  • Treatment for male infertility should be targeted to the aetiological factors whenever possible, and includes hormonal treatment, hormonal modulators, corticosteroids, antioxidants, and surgery. (acupuncture.org.uk)
  • Today attempts are made to specifically identify causes of male infertility such as immunological, infectious or hormonal factors in order to prescribe a specific treatment. (gfmer.ch)
  • Male infertility is typically linked to anatomical or hormonal complications that hinder the production of healthy sperm . (ucsb.edu)
  • Infertility in men can be diagnosed by a simple semen analysis and treatment is available in the form of surgical procedures as well as hormonal medications. (ucsb.edu)
  • Male infertility is caused by hormonal imbalances, physical problems, psychological problems, and behavioral or environmental factors 4 . (ucsb.edu)
  • While a percentage of male infertility is caused by hormonal problems, it is important to understand how lifestyle choices can affect the ability to produce healthy sperm. (ucsb.edu)
  • New research on potential causes of male infertility hold key messages for urologists at this year's AUA annual meeting, according to Craig S. Niederberger, MD, of the University of Illinois, Chicago. (modernmedicine.com)
  • In this segment, Robert D. Oates, MD., joins the show to discuss some of the causes of male infertility and the treatment options available at Boston Medical Center. (bmc.org)
  • So, do we know some of the causes of male infertility? (bmc.org)
  • Even though specialists know the causes of male infertility, what's not always known is the cause behind the cause. (webmd.com)
  • Understand the most common causes of male infertility. (nytimes.com)
  • Causes of Male Infertility Herbert J. Wiser, Jay Sandlow, and Tobias S. Köhler 2. (buecher.de)
  • STONY BROOK U. (US) - A new role for mitochondria may hold clues to some causes of male infertility and in turn could have potential in the future for use in a male contraceptive. (futurity.org)
  • Below are some of the main causes of male infertility. (ahealthyme.com)
  • Both overweight and underweight men can have fertility problems. (webmd.com)
  • just like female infertility, male could have this fertility problems too and mind you this can caused by a number of factors. (womens-health.co.uk)
  • 2. Men even suffer from infertility issues just like women. (slideshare.net)
  • Buy 1 Month Package for Oligospermia $85 Yauvanamrit Vati 10 gm, Chandraprabha Vati 60 gm, Shilajit sat 40 gm Similar to infertility conditions in females, their counterparts i.e. males also suffer from infertility which is sometimes known as oligospermia or male impotency or male infertility. (pearltrees.com)
  • Sperm concentrations of 20 million to 250 million per cubic centimetre are usually considered normal, but fertilization of an egg can be achieved by men with values well below this range. (britannica.com)
  • Fertilization is a fundamental process in sexual reproduction when the combination of male and female gametes blends genetic material to create a new unique individual. (news-medical.net)
  • Different events occurring in the male reproductive system contribute to the composite route of fertilization leading to early embryonic development ( 1 ). (bioscience.org)
  • Although there has been a long-standing debate on the role of CDO and taurine in fertilization, the study suggested that male mice who were tagged as infertile has less taurine in their sperm compared to others. (naturalnews.com)
  • Which has been shown to actually reduce a man's sperm count and lead to infertility ? (go.com)
  • c) Immunologic infertility triggered by a man's immunologic response to his own sperm, due to injury, surgery or infection. (gulfnews.com)
  • Male infertility occurs when a man's sperm cannot successfully fertilize his partner's egg. (ucsb.edu)
  • A Stanford University study found that fertility reflects a man's overall health, and that men who live a healthy lifestyle will more likely produce healthy sperm 4 . (ucsb.edu)
  • men with male factor infertility were 2.6 times more likely to be diagnosed with high-grade prostate cancer. (prweb.com)
  • In the light of multiple studies confirming that most of us are vitamin D deficient - and that vitamin D receptors are replete in sperm - restoring optimal vitamin D levels could have a profound effect upon male-factor infertility. (bellaonline.com)
  • Is anyone familiar with male factor infertility, or more specifically, antisperm antibodies in males? (dailystrength.org)
  • Most people with male factor have to do IVF. (dailystrength.org)
  • Brugh VM 3rd et al: Male factor infertility: evaluation and management. (health.am)
  • If there is a reproductive issue with the male, time is a dependent factor on prospective treatment for the couple, explains Dr. Seth Levrant who participates in the clinic Partners in Reproductive Health in Munster, IN and Tinley Park, IL. (fertilityauthority.com)
  • They compared outcomes among 13,027 men diagnosed with male factor infertility (average age, 33 years), with outcomes among 23,860 men (average age, 33 years) who received semen or infertility testing and with outcomes among 79,099 men who had received vasectomies. (medscape.com)
  • The link between male factor infertility and future adverse health remains uncertain, although several convincing explanations have been proposed," the authors write. (medscape.com)
  • If you have male factor infertility, chances are it's treatable. (ochsner.org)
  • This is referred to as male factor infertility . (advancedfertility.com)
  • Currently the therapy for male factor infertility focuses on intricate microsurgery to correct varicoceles or obstruction of the male reproductive ductal system. (pulsemed.org)
  • Acupuncture may represent an important therapeutic modality for male factor infertility. (pulsemed.org)
  • Besides this, male factor infertility has been found to be linked with some rare X-linked copy number variations (CNVs), autosomal deletions, Y-linked syndromes, DNA repair mechanism defects, and some single nucleotide polymorphisms (SNPs) ( 8 , 9 , 10 , 11 ). (bioscience.org)
  • Specific treatment for male factor infertility will be determined by your doctor based on your age, overall health, medical history and your tolerance for specific medications, procedures or therapies. (integrisok.com)
  • Vitamin D Receptor Polymorphism and Male Factor Infertility. (thefreelibrary.com)
  • Over the last 25 years, the application of advanced microsurgical techniques has made the treatment of the infertile male one of the great success stories in medicine. (inciid.org)
  • The initial step in the evaluation of an infertile male is to obtain a thorough medical and urologic history. (medscape.com)
  • A complete examination of the infertile male is important to identify general health issues associated with infertility. (bionity.com)
  • WHO manual for the standardized investigation and diagnosis of the infertile male. (acupuncture.org.uk)
  • Further evaluation of the man should be considered beyond optimizing and obtaining sperm, including continued surveillance of the infertile male in the years after reproductive efforts cease. (medscape.com)
  • The diagnosis of infertility begins with a medical history and physical exam by a urologist, preferably one with experience or who specializes in male infertility. (bionity.com)
  • For some men, a diagnosis of infertility can be devastating. (ochsner.org)
  • Clomiphene citrate (Clomid or Serophene) is an anti-estrogen drug designed as a fertility medicine for women but sometimes used to boost sperm production in men with low sperm counts and poor sperm motility. (drugs.com)
  • Mutations in mitochondrial DNA have been linked to poor sperm motility and raise the possibility that some types of male subfertility may be inherited only through the female line. (clinicaltrials.gov)
  • Benefits of herbal package of medicine for treating oligospermia/ male impotency. (pearltrees.com)
  • Male fertility issues include patients who have problems with sperm production or obstruction of sperm release from the reproductive system. (massgeneral.org)
  • Warning signs are rare, but some infertile men have lumps or swelling near the testicles, breast growth, erectile dysfunction, and respiratory problems. (wikihow.com)
  • Male infertility problems can occur when sperms are limited in number or function. (hindawi.com)
  • These facts, together with an obvious change in social psychology, have facilitated the development of different specialities dealing with the problems of infertility. (springer.com)
  • Practitioners across many specialties - including urologists, gynecologists, reproductive endocrinologists, medical endocrinologists and many in internal medicine and family practice - will see men with suboptimal fertility and reproductive problems. (cambridge.org)
  • Male infertility can also occur when there are problems with ejaculation. (americanpregnancy.org)
  • As nature would have it, problems with infertility are equally due to male and female conditions. (webmd.com)
  • Statistics suggest that 35 to 40 percent of the problems are caused by male conditions, another 35 to 40 percent by female conditions, and the last 20 to 30 percent a combination of the two, plus a small percentage of unknown causes. (webmd.com)
  • Men are considered infertile if they produce too few sperm cells, sperm cells of poor quality, or have chronic problems with ejaculation. (upmc.com)
  • During the initial consult, both partners will be evaluated for infertility problems. (upmc.com)
  • Infertility can be due to the woman (33%), the man (33%) and by both sexes or due to unknown problems (33%), approximately. (medicinenet.com)
  • if a men in your family have infertility problems, then maybe you sort of getting that too. (womens-health.co.uk)
  • Diagnosis begins with a complete physical examination of the man to determine his general state of health and identify any physical problems that may impact his fertility. (clevelandclinic.org)
  • Male infertility can be caused by problems with sperm count, movement or shape, as well as blockages that prevent the delivery of sperm. (fertilityauthority.com)
  • Men can also have problems expressing their concerns with infertility to their partners. (articleinsider.com)
  • The gene encodes for a protein that has a critical role in the development of the reproductive organs and in reproduction, and has previously been linked to problems with sexual development in both men and women. (bionews.org.uk)
  • To date only a small number of genes have been linked to male infertility, with the majority of sperm production problems having no obvious cause. (bionews.org.uk)
  • Sometimes a man is born with the problems that affect his sperm. (sharecare.com)
  • Though the exact causes of these problems are unknown, Skakkebaek suspects the industrialization of many countries after World War II and their increased exposure to chemical pollutants, including endocrine disrupting chemicals (EDCs), may have had a role in impairing male reproductive health. (japantimes.co.jp)
  • Problems with either of these may mean you have infertility. (ahealthyme.com)
  • Your provider does these tests to find the cause of sperm defects or health problems of the male reproductive system. (ahealthyme.com)
  • If the man is specifically identified as having the fertility problem (i.e., low sperm count, deformity in anatomy, problems with ejaculation, etc.), there is a significant body of research suggesting this is detrimental to his sense of self and his masculinity. (goodmenproject.com)
  • For men reading this that are experiencing difficulties, please seek medical treatment to determine the cause of the infertility problems, if possible. (goodmenproject.com)
  • in 60% of men affected by an inflammation/infection of the epididymis, the testes were affected too. (eurekalert.org)
  • Such interventions gain more importance in light of reports that, paralleling the population body mass index (BMI) increase, the prevalence of male infertility is increasing as evidenced by decreasing sperm counts throughout the world over the last few decades. (medscape.com)
  • Intracytoplasmic sperm injection (ICSI) is a treatment for men with very low sperm counts or with sperm that for some other reason are unable to fertilize an egg. (britannica.com)
  • Whilst these young men may have lower sperm counts than the general population, they may still be able to father children without treatment," says Adam Balen, of the British Fertility Society . (newscientist.com)
  • Physicians in the Male Infertility Center are among the most experienced in the country in performing in-depth analyses to determine sperm counts, viability (sperm's ability to survive), morphology (sperm quality and shape) and motility (the sperm's ability to move to the egg to fertilize it). (clevelandclinic.org)
  • Still, as many as 80 percent of men who are infertile have low sperm counts. (nytimes.com)
  • Pass it on: Obese or overweight men are more likely to suffer infertility due to poor sperm counts or lack of viable sperm. (livescience.com)
  • We know that men with low sperm counts can sometimes have children - and some men with normal sperm counts can be infertile. (advancedfertility.com)
  • Men who admitted to having ever smoked marijuana were more likely to have higher sperm counts than men who had never hit the bong. (askmen.com)
  • One in ten men suffers low sperm counts. (films.com)
  • The study was part of wider research into so-called "endocrine‑disrupting" chemicals that for several years have been linked with declining sperm counts and widespread male infertility. (independent.ie)
  • 12. Medication, which can treat some issues that affect male fertility, including hormone imbalances & erectile dysfunction. (slideshare.net)
  • It is the herb of choice for men who suffer from erectile dysfunction (claibya), low sexual strength (daurbalya) and low body weight. (ayurhelp.com)
  • Male erectile dysfunction can be defined as the inability of a man to obtain penile rigidity sufficient to permit coitus of adequate duration to satisfy himself and his partner. (pulsemed.org)
  • Recent advances in medical therapies for erectile dysfunction has raised public awareness of the condition, however many men shy away from conventional therapies due to concerns of side effects and lack of efficacy. (pulsemed.org)
  • The purpose of this paper is to provide an introduction to the history of Traditional Chinese Medicine (TCM) and the basic philosophy and principles used to understand male erectile dysfunction and infertility from an Eastern medical perspective. (pulsemed.org)
  • Men who have had a vasectomy reversal are especially likely to have antisperm antibodies. (dailystrength.org)
  • This includes men with fertility issues following chemotherapy and men who want to try and reverse a vasectomy. (hfea.gov.uk)
  • Sensorineural deafness and male infertility is a condition characterized by hearing loss and an inability to father children. (medlineplus.gov)
  • Infertility is the inability to get pregnant after one year of unprotected sexual intercourse. (webmd.com)
  • Diagnostic evaluation and management of male subfertility. (nih.gov)
  • The diagnostic evaluation of male subfertility begins with an evaluation of the couple. (nih.gov)
  • The infertility experience for many can range from multiple diagnostic procedures through progressively more aggressive treatment options, all of which impose demands upon the emotional and physical self. (medicinenet.com)
  • In their article, the authors from Justus Liebig University Giessen summarize what is currently known about the possible effects of urogenital infections on male fertility and make recommendations on diagnostic and therapeutic approaches. (eurekalert.org)
  • The diagnostic evaluation of urogenital infections in most patients with infertility is hampered by an asymptomatic primary chronic disease course. (eurekalert.org)
  • A study to be presented at the annual conference of the European Society of Human Genetics tomorrow (Saturday) has uncovered new potential genetic causes, and this discovery will help to develop better diagnostic tests for male infertility. (eurekalert.org)
  • The results will help establish new diagnostic tests, which will be able to provide a patient with a detailed analysis of the reason for his infertility, and allow for personalised care. (eurekalert.org)
  • A standard set of diagnostic exams are typically sufficient to identify the cause of an individual's male infertility. (sharecare.com)
  • Comparing 54 men who were conceived using ICSI with 57 men whose parents conceived naturally, Andre Van Steirteghem at the Vrije Universiteit Brussel in Belgium and his colleagues have found that the ICSI men had almost half the sperm concentration of the control group, and a two-fold lower count of motile sperm. (newscientist.com)
  • The ICSI men were all born between 1992 and 1996, during the early years of the technique. (newscientist.com)
  • It doesn't automatically follow that ICSI-conceived males will always have the poor fertility seen by their fathers," he says. (newscientist.com)
  • In case of treatment failure, depending on the severity of male infertility, insemination, IVF or microfertilisation (ICSI) can be tried regardless of the etiology. (gfmer.ch)
  • Studies of children fathered through intracytoplasmic sperm injection or ICSI have revealed mutations on the AZF region of the Y chromosome linked to male infertility. (clinicaltrials.gov)
  • Sunlight may be good for male as well as female fertility according to new research. (bellaonline.com)
  • hi adonis, this is a fair illness to both sexes whether you are male or female, you have no escape on this matter. (womens-health.co.uk)
  • Women who have not previously undergone infertility testing may be referred to a female infertility specialist in the Cleveland Clinic Ob/Gyn & Women's Health Institute . (clevelandclinic.org)
  • In most conventionally patriarchal societies, the UAE being no exception, the female partner is often blamed for infertility. (gulfnews.com)
  • The balance 20-30 per cent was a combination of both male and female factors. (gulfnews.com)
  • Addresses both male and female infertility. (herbs.org)
  • As with female reproduction, male reproduction is hormonally driven, requiring a normally functioning hypothalamus and pituitary gland. (ucsfhealth.org)
  • When a couple is having trouble conceiving a child, 50% of the time infertility issues can be traced back to the female, 30% of the time to the male, and 20% of the time to both. (ochsner.org)
  • Typically, infertility in men is correlated with any health issue that lowers the chances of his female partner getting pregnant 5 . (ucsb.edu)
  • Male infertility is responsible for 40% of failed pregnancies, while 40% are female infertility issues, and 20% of the time there are complications with both partners 3 . (ucsb.edu)
  • However, the female should also be evaluated prior to the surgery - if her tubes are blocked or she has anovulation (no ovulation), or an ovarian reserve problem , surgery on the male is not indicated. (advancedfertility.com)
  • When it comes to female and male infertility, a couple's main concern is usually the odds of gettin. (a1articles.com)
  • Female Infertility: Disease and…Eas. (films.com)
  • You may have male infertility if your female partner has not become pregnant after you have tried for 1 year. (ahealthyme.com)
  • Simple, inexpensive, and effective therapeutic interventions for male infertility are needed. (medscape.com)
  • This report provides comprehensive information on the therapeutic development for Male Infertility, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. (pitchengine.com)
  • It also reviews key players involved in the therapeutic development for Male Infertility and special features on late-stage and discontinued projects. (pitchengine.com)
  • The findings could also inform a field of stem cell research known as nuclear transfer, or therapeutic cloning, which aims to provide tailor-made stem cells to aid disease therapy and infertility. (rxpgnews.com)
  • The observation that no medication is approved by the United States Food and Drug Administration for treatment of male infertility confirms the conclusion that adequate controlled studies of potential therapeutic agents are either lacking or failed to elicit a significant improvement in fertility. (pulsemed.org)
  • Although the most common cause of male subfertility is idiopathic failure of spermatogenesis, a significant percentage of male subfertility is medically treatable. (nih.gov)
  • Now, these findings provide evidence that male infertility also plays a significant role in determining risk," said Dr. Turek. (prweb.com)
  • This study confirms our earlier published work with testis cancer and suggests that male infertility may be an early marker for later disease in men,' according to Dr. Turek. (prweb.com)
  • A complete biography of Dr. Turek is available on Wikipedia at http://en.wikipedia.org/wiki/Paul_J._Turek . (prweb.com)
  • The study suggested that a deficiency in taurine , a vital amino acid which is found abundantly in the male reproductive system, can deform sperm and may lead to male infertility. (naturalnews.com)
  • What Treatment Options Are Available for Male Infertility? (medlineplus.gov)

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