Immunocompromised Host
Immunocompetence
Opportunistic Infections
Pneumocystis carinii
Antifungal Agents
Aspergillus fumigatus
Trichosporon
Strongyloidiasis
Central Nervous System Infections
Pathogenic infections of the brain, spinal cord, and meninges. DNA VIRUS INFECTIONS; RNA VIRUS INFECTIONS; BACTERIAL INFECTIONS; MYCOPLASMA INFECTIONS; SPIROCHAETALES INFECTIONS; fungal infections; PROTOZOAN INFECTIONS; HELMINTHIASIS; and PRION DISEASES may involve the central nervous system as a primary or secondary process.
Mucormycosis
Infection in humans and animals caused by any fungus in the order Mucorales (e.g., Absidia, Mucor, Rhizopus etc.) There are many clinical types associated with infection of the central nervous system, lung, gastrointestinal tract, skin, orbit and paranasal sinuses. In humans, it usually occurs as an opportunistic infection in patients with a chronic debilitating disease, particularly uncontrolled diabetes, or who are receiving immunosuppressive agents. (From Dorland, 28th ed)
Strongyloides stercoralis
Fatal Outcome
Cytomegalovirus Infections
Transplantation
Cytomegalovirus
A genus of the family HERPESVIRIDAE, subfamily BETAHERPESVIRINAE, infecting the salivary glands, liver, spleen, lungs, eyes, and other organs, in which they produce characteristically enlarged cells with intranuclear inclusions. Infection with Cytomegalovirus is also seen as an opportunistic infection in AIDS.
Candidiasis
Parasitic Diseases
Lung Diseases, Fungal
Bacteremia
The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.
Aspergillus
Cryptococcus neoformans
Immunologic Deficiency Syndromes
Amphotericin B
Cryptosporidiosis
Organ Transplantation
AIDS-Related Opportunistic Infections
Opportunistic infections found in patients who test positive for human immunodeficiency virus (HIV). The most common include PNEUMOCYSTIS PNEUMONIA, Kaposi's sarcoma, cryptosporidiosis, herpes simplex, toxoplasmosis, cryptococcosis, and infections with Mycobacterium avium complex, Microsporidium, and Cytomegalovirus.
Pneumonia, Pneumocystis
A pulmonary disease in humans occurring in immunodeficient or malnourished patients or infants, characterized by DYSPNEA, tachypnea, and HYPOXEMIA. Pneumocystis pneumonia is a frequently seen opportunistic infection in AIDS. It is caused by the fungus PNEUMOCYSTIS JIROVECII. The disease is also found in other MAMMALS where it is caused by related species of Pneumocystis.
Candida
A genus of yeast-like mitosporic Saccharomycetales fungi characterized by producing yeast cells, mycelia, pseudomycelia, and blastophores. It is commonly part of the normal flora of the skin, mouth, intestinal tract, and vagina, but can cause a variety of infections, including CANDIDIASIS; ONYCHOMYCOSIS; vulvovaginal candidiasis (CANDIDIASIS, VULVOVAGINAL), and thrush (see CANDIDIASIS, ORAL). (From Dorland, 28th ed)
Immunosuppression
Deliberate prevention or diminution of the host's immune response. It may be nonspecific as in the administration of immunosuppressive agents (drugs or radiation) or by lymphocyte depletion or may be specific as in desensitization or the simultaneous administration of antigen and immunosuppressive drugs.
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Fungi
A kingdom of eukaryotic, heterotrophic organisms that live parasitically as saprobes, including MUSHROOMS; YEASTS; smuts, molds, etc. They reproduce either sexually or asexually, and have life cycles that range from simple to complex. Filamentous fungi, commonly known as molds, refer to those that grow as multicellular colonies.
Polymerase Chain Reaction
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Virulence
Antiviral Agents
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
Acquired Immunodeficiency Syndrome
An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.
Sequence Analysis, DNA
Virus Replication
Lung
Disease Models, Animal
Immunosuppressive Agents
Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.
Interferon-gamma
The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
Microbial Sensitivity Tests
DNA, Ribosomal
Drug Therapy, Combination
Host Specificity
Invasive Pulmonary Aspergillosis
Cells, Cultured
Host-Pathogen Interactions
Host-Parasite Interactions
Rhodococcus equi
Toxoplasma
In vitro and in vivo activities of NS-718, a new lipid nanosphere incorporating amphotericin B, against Aspergillus fumigatus. (1/2546)
We evaluated the in vitro and in vivo potencies of a new lipid nanosphere that incorporates amphotericin B (AmB), NS-718, against Aspergillus fumigatus. The in vitro activity of NS-718 (the MIC at which 90% of strains are inhibited [MIC90], 0.25 microgram/ml) against 18 isolates of A. fumigatus was similar to that of deoxycholate AmB (D-AmB; Fungizone; MIC90, 0.25 microgram/ml), but NS-718 was more potent than liposomal AmB (L-AmB; AmBi-some; MIC90, 1.0 microgram/ml). The in vivo efficacy of NS-718 in a rat model of invasive pulmonary aspergillosis was compared with those of D-AmB and L-AmB. A low dose (1 mg/kg of body weight) of L-AmB was ineffective (survival rate, 0%), although equivalent doses of D-AmB and NS-718 were more effective (survival rate, 17%). However, a higher dose of NS-718 (3 mg/kg) was more effective (survival rate, 100%) than equivalent doses of D-AmB and L-AmB (survival rate, 0%). To explain these differences, pharmacokinetic studies showed higher concentrations of AmB in the plasma of rats treated with NS-718 than in the plasma of those treated with D-AmB. Our results suggest that NS-718, a new preparation of AmB, is a promising antifungal agent with activity against pulmonary aspergillosis. (+info)International travel and vaccinations. (2/2546)
With the increase in global travel, no disease is beyond the reach of any population. Traveling patients should be advised to follow food and water precautions and encouraged to receive the recommended immunizations. Travel medicine plays a vital role not only in limiting the morbidity of travel-related illnesses but also in limiting the spread of diseases. This article addresses the common issues related to travel, reviews the care of the immunocompromised traveler, and updates the available vaccinations and prophylactic regimens available to limit sickness abroad. (+info)Amebic liver abscess: epidemiology, clinical features, and outcome. (3/2546)
Amebic liver abscess (ALA) is a serious, but readily treatable form of hepatic infection. In order to understand the clinical features of this condition in the United States, we reviewed the medical histories of 56 patients with ALA at two large San Francisco Hospitals from 1979 to 1994. Patients were divided into the following groups based on the presumed manner in which they had acquired ALA: those born or raised in the United States, with a history of travel to an endemic area (Tr-ALA); those from an endemic area, but living in the United States for less than one year (En-ALA); and those neither from nor having traveled to an endemic area (N-ALA). We found distinct clinical patterns in patients from different epidemiological groups. Patients with Tr-ALA were a decade older than those from endemic regions, were more likely to be male, and tended to have an insidious onset. Furthermore, compared to patients with En-ALA, those with Tr-ALA were more likely to have hepatomegaly (P < 0.0001) and large abscesses (ALA > 10 cm; P < 0.01). One third of the patients studied had no associated travel history or endemic origin as risk factors. Of these, 63% had a condition consistent with severe immunosuppression, such as infection with the human immunodeficiency virus (HIV), malnourishment with severe hypoalbuminemia, or chronic infection. In patients with N-ALA, the presence of a presumed immunosuppressed state increased significantly, as compared to patients with endemic or travel risk factors for ALA. During the last five years of the study, one third of all patients diagnosed with ALA were HIV positive (including 2 with a new diagnosis of AIDS), many of whom were discovered to be HIV-infected only after presentation with ALA. We conclude that travel to and origin in an endemic area are important risk factors for the development of ALA, and patients in these different epidemiological groups appear to have distinct clinical features. Further, in the absence of recognized risk factors, the development of ALA may suggest an immunocompromised host. (+info)Actinomyces and nocardia infections in immunocompromised and nonimmunocompromised patients. (4/2546)
A retrospective survey of nocardia and actinomyces infections in five local hospitals was conducted over a 3-year period in El Paso, Texas, a border city, in the southwestern United States. The medical records of 42 patients with suspected nocardiosis or actinomycosis were reviewed. One patient was diagnosed with actinomyces and 12 patients with nocardia. Microbiological data included morphologic characteristics, biochemical profile, and susceptibility testing. Predisposing factors included leukemia, renal insufficiency, renal transplant, and lymphoma. No predisposing factors were found in 67% (n = 8) of patients (including the patient with actinomycosis). Twenty-three percent (n = 3) of patients had disseminated disease without evidence of underlying disease or immunosuppression. The mortality and morbidity of these infections appeared to be low. (+info)Restricted isotypic antibody reactivity to hepatitis C virus synthetic peptides in immunocompromised patients. (5/2546)
An enzyme immunoassay based on three synthetic peptides from the core, NS4, and NS5 regions of hepatitis C virus allowed the detection of antibodies in 100% of immunocompetent infected patients and in 91% of immunocompromised patients (hemodialysis and hemophiliac patients). Immune impairment seemed to restrict the spectrum of antibody isotypes reacting to the core peptide. (+info)Fatal disseminated Trichoderma longibrachiatum infection in an adult bone marrow transplant patient: species identification and review of the literature. (6/2546)
Trichoderma longibrachiatum was recovered from stool surveillance cultures and a perirectal ulcer biopsy specimen from a 29-year-old male who had received an allogeneic bone marrow transplant for acute lymphoblastic leukemia. The amphotericin B (2.0 microgram/ml) and itraconazole (1.0 microgram/ml) MICs for the organism were elevated. Therapy with these agents was unsuccessful, and the patient died on day 58 posttransplantation. At autopsy, histologic sections from the lungs, liver, brain, and intestinal wall showed infiltration by branching septate hyphae. Cultures were positive for Trichoderma longibrachiatum. While Trichoderma species have been recognized to be pathogenic in profoundly immunosuppressed hosts with increasing frequency, this is the first report of probable acquisition through the gastrointestinal tract. Salient features regarding the identification of molds in the Trichoderma longibrachiatum species aggregate are presented. (+info)Human rabies prevention--United States, 1999. Recommendations of the Advisory Committee on Immunization Practices (ACIP). (7/2546)
These revised recommendations of the Advisory Committee on Immunization Practices update the previous recommendations on rabies prevention (MMWR 1991;40[No.RR-3]:1-14) to reflect the current status of rabies and antirabies biologics in the United States. This report includes new information about a human rabies vaccine approved for U.S. use in 1997, recommendations regarding exposure to bats, recommendations regarding an observation period for domestic ferrets, and changes in the local administration of rabies immune globulin. (+info)Candida dubliniensis candidemia in patients with chemotherapy-induced neutropenia and bone marrow transplantation. (8/2546)
The recently described species Candida dubliniensis has been recovered primarily from superficial oral candidiasis in HIV-infected patients. No clinically documented invasive infections were reported until now in this patient group or in other immunocompromised patients. We report three cases of candidemia due to this newly emerging Candida species in HIV-negative patients with chemotherapy-induced immunosuppression and bone marrow transplantation. (+info)
Respiratory syncytial virus pneumonitis in immunocompromised adults: clinical features and outcome
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Albendazole
St Georgiev V (1997). Infectious Diseases in Immunocompromised Hosts. CRC Press. p. 695. ISBN 978-0-8493-8553-7. Riviere JE, ... Elimination of Wolbachia from these filarial nematodes generally results in either death or sterility of the host nematode. ... is found in higher concentrations in the infected host tissues, and is found in higher concentrations within the parasites ...
Dimitrios Kontoyiannis
"International Immunocompromised Host Society - home". ichs.org. "American Association for the Advancement of Science - home". ... Kontoyiannis is the past president-elect of Immunocompromised Host Society (2016-2018) Kontoyiannis is also a fellow of the ...
Exophiala dermatitidis
1998). Infectious diseases in immunocompromised hosts. Boca Raton: CRC Press. p. 909. ISBN 0849385539. Retrieved 16 October ... The host responses are highly variable, often include cyst formation, and vary from weak reaction to an intense inflammatory ... and host factors such as immunological differences may be responsible for the different infection patterns. Exophiala ...
Microascus manginii
Scopulariopsis candida has been identified as the cause of some invasive infections, often in immunocompromised hosts, but is ... "Invasive scopulariopsis in the immunocompromised host". The American Journal of Medicine. 83 (6): 1163-1166. doi:10.1016/0002- ... The patient was immunocompromised at the time of fungal infection due to ongoing cancer treatment. The clinical presentation ... marked the first successful treatment of an invasive infection caused by Scopulariopsis species in an immunocompromised host. ...
Clostridium cadaveris
Gucalp, R.; Carlisle,Dutcher,Fuks,Wiernik (1993). "Clostridium cadaveris bacteremia in the immunocompromised host". Med. ... Most cases reported in medical literature document infections in immunocompromised patients, but isolated cases in ... "Clostridium cadaveris in an Immunocompetent Host". Clinical Infectious Diseases. 29 (5): 1354-1355. doi:10.1086/313491. PMID ... immunocompetent hosts have been reported. Primary isolation media is blood agar incubated anaerobically at 35-37 degrees ...
Human papillomavirus infection
Diagnostic Microbiology of the Immunocompromised Host (Second ed.). American Society of Microbiology. 4 (4): 177-195. doi: ... Virions can then be sloughed off in the dead squames of the host epithelium and the viral lifecycle continues. A 2010 study has ... HPV can survive for many months and at low temperatures without a host; therefore, an individual with plantar warts can spread ... HPV genomes integrate into host genome by disruption of E2 ORF, preventing E2 repression on E6 and E7. Thus, viral genome ...
Philip A. Pizzo
"International Immunocompromised Host Society - 2021 ICHS Achievement Awards". www.ichs.org. Retrieved 2022-06-06. "Philip A. ... 2019 International Immunocompromised Host Society Lifetime Achievement Award, 2021 Pizzo is the author of 646 scientific ...
Fungal folliculitis
This disease commonly affects both immunocompetent and immunocompromised hosts. However, immunocompromised individuals have a ... The fungi are usually unable to penetrate into viable tissues in an immunocompetent host and therefore the infection incidence ... fluctuant subcutaneous nodules or abscesses represent a second form of MG that is generally observed in immunosuppressed hosts ... that usually occurs in healthy individuals deep subcutaneous plaque/nodular lesion form that occurs in immunosuppressed hosts. ...
Arcobacter ebronensis
"Bacteremia caused by Arcobacter butzleri in an immunocompromised host." Journal of Clinical Microbiology 53.4 (2015): 1448-1451 ...
Balamuthia mandrillaris
Mannan Baig, Abdul (Dec 2014). "Granulomatous amoebic encephalitis: ghost response of an immunocompromised host?". J Med ... Pathogenesis of amoebic encephalitis: Are the amoebas being credited to an 'inside job' done by the host immune response? Acta ... This granulomatous feature is mostly seen in immunocompetent patients; immunocompromised individuals exhibit a "perivascular ...
Acanthamoeba
Baig AM (December 2014). "Granulomatous amoebic encephalitis: ghost response of an immunocompromised host?". Journal of Medical ... The combination of host immune responses and secreted amoebal proteases causes massive brain swelling resulting in death in ... Members of the genus Acanthamoeba are unusual in serving as hosts for a variety of giant viruses (that have more than 1000 ... The exact nature of these symbionts and the benefit they represent for the amoebic host still have to be clarified. These ...
List of human disease case fatality rates
... ghost response of an immunocompromised host?". Journal of Medical Microbiology. 63 (Pt 12): 1763-1766. doi:10.1099/jmm.0.081315 ...
Lymphocyte T-cell immunomodulator
"Immune-enhancing agent for therapeutic use in immunocompromised hosts (US5616554A)". Google Patent. 26 July 1994. Retrieved 4 ...
Mucormycosis
Cutaneous Manifestations of Infection in the Immunocompromised Host (2nd ed.). Springer. pp. 51-58. ISBN 978-1-4419-1577-1. " ... Skin (cutaneous); after a burn, or other skin injury, in people with leukaemia, poorly controlled diabetes, graft-versus-host ... usually in people who are immunocompromised. It is curable only when diagnosed early. Symptoms depend on where in the body the ...
Vibrio alginolyticus
V. alginolyticus is rare cause of bacteremia in immunocompromised hosts. Colony, morphological, physiological, and biochemical ...
Varicella vaccine
Pirofski LA, Casadevall A (January 1998). "Use of licensed vaccines for active immunization of the immunocompromised host". ... Household contacts of immunocompromised individuals, Members of a household expecting a newborn, Health care workers, Adults ... mainly in inadvertently vaccinated immunocompromised children) as well as anaphylaxis. The possible mild side effects include ...
Cocooning (immunization)
"2013 IDSA Clinical Practice Guideline for Vaccination of the Immunocompromised Host". Clinical Infectious Diseases. 58 (3): e44 ... However, some attenuated vaccines are not recommended for people living with immuno-compromised people, depending on the ... "MODULE 2 - Immunizing the immunocompromised - WHO Vaccine Safety Basics". vaccine-safety-training.org. World Health ... People who are severely immuno-compromised may not be able to take some vaccines; on the other hand, they may be much more ...
Nocardia asteroides
It can cause nocardiosis, a severe pulmonary infection in immunocompromised hosts. Roth A, Andrees S, Kroppenstedt RM, Harmsen ...
Corynebacterium
Some attack healthy hosts, while others tend to attack the immunocompromised. Effects of infection include granulomatous ... or weakened host defenses. The genus Corynebacterium was created by Lehmann and Neumann in 1896 as a taxonomic group to contain ... neutropenic or immunocompromised patients, and those with prosthetic devices such as prosthetic heart valves, shunts, or ... most commonly existing in commensal relationships with their hosts. Some are useful in industrial settings such as C. ...
Immune system
Joos L, Tamm M (2005). "Breakdown of pulmonary host defense in the immunocompromised host: cancer chemotherapy". Proceedings of ... providing a direct route for proteins to move from the pathogen to the host. These proteins are often used to shut down host ... Masking antigens with host molecules is another common strategy for avoiding detection by the immune system. In HIV, the ... The innate immune system is the dominant system of host defense in most organisms, and the only one in plants. Cells in the ...
Hairy leukoplakia
Uncontrolled lytic infection is manifested as oral hairy leukoplakia in immunocompromised hosts. OHL usually arises where the ... OHL may also accompany chronic graft versus host disease. Even more rare are reports of OHL in persons with competent immune ... It is caused by Epstein-Barr virus (EBV) and occurs usually in persons who are immunocompromised, especially those with human ... the virus will persist for the rest of the host's life and "hides" from the immune system by latent infection of B lymphocytes ...
Trichodysplasia spinulosa polyomavirus
... a newly described folliculocentric viral infection in an immunocompromised host". The Journal of Investigative Dermatology. ... TSPyV has been associated with disease only in severely immunocompromised individuals, and then only in a small minority of ... Trichodysplasia spinulosa is a proliferative skin disorder that occurs in immunocompromised people and is considered benign, ... 2010). "Discovery of a New Human Polyomavirus Associated with Trichodysplasia Spinulosa in an Immunocompromized Patient". PLOS ...
Trichodysplasia spinulosa
... a newly described folliculocentric viral infection in an immunocompromised host". The Journal of Investigative Dermatology. ... This pattern is consistent with the behavior of other viral diseases found in immunocompromised patients, most relevantly with ... TS has been reported almost exclusively in immunocompromised patients, primarily organ transplant recipients on regimens of ... is a rare cutaneous condition that has been described almost exclusively in immunocompromised patients, usually organ ...
Tuberculosis in relation to HIV
Airborne transmission typically causes TB infection in both immunocompetent and immunocompromised hosts.[citation needed] ... Tuberculosis is the most common contagious infection in HIV-Immunocompromised patients leading to death. These diseases act in ...
Eikenella corrodens
E. corrodens could independently cause serious infection in both immunocompetent and immunocompromised hosts. Eikenella ...
Panophthalmitis
... and ecthyma gangrenosum in an immunocompromised host with pseudomonas septicemia". American Journal of Ophthalmology. 137 (1): ...
Cryptococcus neoformans
... can cause disease in apparently immunocompetent, as well as immunocompromised, hosts. Cryptococcus ... diabetic and immunocompromised hosts. The infection from C. neoformans in the brain can be fatal if untreated. CNS (central ... Under host-relevant conditions, including low glucose, serum, 5% carbon dioxide, and low iron, among others, the cells produce ... It has been speculated that this ability to manipulate host cells results from environmental selective pressure by amoebae, a ...
Epiglottitis
"Acute Epiglottitis in the Immunocompromised Host: Case Report and Review of the Literature". Open Forum Infectious Diseases. 5 ... Underlying disorders of the immune system, such as graft-versus-host disease and lymphoproliferative disorders, have also been ... There have been many cases of epiglottitis reported in immunocompromised patients, including those undergoing cancer treatment ...
Diffuse large B-cell lymphoma associated with chronic inflammation
... and NK-Cell Derivation in Non-Immunocompromised Hosts". Pathogens (Basel, Switzerland). 7 (1): 28. doi:10.3390/pathogens7010028 ... a protein that helps these cells avoid attack by host cytotoxic T-cells and also blocks their apoptosis responses thereby ... antibody that binds to the CD20 cell surface protein on B-cells to thereby target these cells for attack by the hosts adaptive ...
Sporothrix schenckii
Inhalation of spores is a rare route of infection largely associated with immunocompromised hosts. The cutaneous form of ... In host tissue it is found as a yeast. The transition between the hyphal and yeast forms is temperature dependent making S. ... Growing at host body temperature (37 °C (99 °F)) is an important requirement for pathogenesis. Some strains of S. schenckii are ... Immunocompromised individuals are at increased risk of infection and such patients often exhibit more severe forms of disease. ...
Norovirus
Entry into the host cell is achieved by attachment to host receptors, which mediates endocytosis. Positive-stranded RNA virus ... Norovirus can establish a long term infection in people who are immunocompromised, such as those with common variable ... The norovirus can survive for long periods outside a human host depending on the surface and temperature conditions: it can ... Humans and other mammals serve as the natural host. Transmission routes are fecal-oral and contamination. When a person becomes ...
2022 monkeypox outbreak
When questioning the host about whether he would get a monkeypox vaccine, and the host says yes; Jair Bolsonaro replied: "I'm ... "An immunocompromised Maryland resident with monkeypox has died". The Washington Post. Retrieved 21 October 2022. "Massachusetts ... The host remains in his serious speech on the subject, Bolsonaro commented: "Don't you understand?" clarifying the homophobic ... Cases in children and immunocompromised people are more likely to be severe. Monkeypox spreads through close, personal, often ...
Leishmania braziliensis
It is an infectious disease that is spread by a parasite in sandflies that use domestic dogs as hosts. The emergence of ... The migrants and those that remained in Ceará were malnourished, immunocompromised, and suffered from poor or even lack of ... Leishmania braziliensis, like other species of Leishmania rely on asexual reproduction in the intermediate mammalian host to ... of the mammalian host, with the macrophages being the target white blood cell of the parasite. Recently, it has been ...
Saksenaea vasiformis
There has been some reported cases of immunocompromised hosts due to steroid treatment, antibiotic therapy, and compromised ... Human hosts are usually immunocompetent with open lesion that acts as a portal entry of the fungus into the body. ...
Histoplasma capsulatum
... budding yeast form in the warm-blooded animal host. Like B. dermatitidis, H. capsulatum has two mating types, "+" and "-". The ... some cases are detected by emergence of serious infection when a patient becomes immunocompromised, perhaps decades later. ...
COVID-19
Multiple viral and host factors affect the pathogenesis of the virus. The S-protein, otherwise known as the spike protein, is ... including immunocompromised people. Infectious particles range in size from aerosols that remain suspended in the air for long ... S2 mediates the membrane fusion of the virus to its potential cell host via the H1 and HR2, which are heptad repeat regions. ... The virus uses a special surface glycoprotein called a "spike" to connect to the ACE2 receptor and enter the host cell. ...
Oral candidiasis
Patients who are immunocompromised, either with HIV/AIDS or as a result of chemotherapy, may require systemic prevention or ... This candidal carriage state is not considered a disease, but when Candida species become pathogenic and invade host tissues, ... When Candida species cause lesions - the result of invasion of the host tissues - this is termed candidiasis. Some consider ... Chronicity of this subtype generally occurs in immunocompromised states, (e.g., leukemia, HIV) or in persons who use ...
Aspiration pneumonia
... immunocompromised, history of smoking, antibiotic therapy, advanced age, reduced pulmonary clearance, diminished cough reflex, ... in combination with impaired host immune function. Chronic inflammation of the lungs is a key feature in aspiration pneumonia ...
2022 in the United States
Biden hosts French President Emmanuel Macron for a state visit, his first as President of the United States. December 2 - The ... August 30 Texas reports an immunocompromised patient has suffered the first US death in the monkeypox outbreak. Bad Bunny ... The 74th Primetime Emmy Awards are held at the Microsoft Theater and hosted by Kenan Thompson. The top prizes go to The White ... March 27 - The 94th Academy Awards, hosted by Regina Hall, Amy Schumer and Wanda Sykes, are held at Dolby Theatre in Los ...
Orf (disease)
While orf is usually a benign self-limiting illness which resolves in 3-6 weeks, in the immunocompromised it can be very ... Couch, Alan John (1983). The Development of, and Host Response to, Ovine Contagious Pustular Dermatitis (BS). University of New ...
Acute necrotizing ulcerative gingivitis
It is now understood that its association with HIV/AIDS was due to the immunocompromised status of such patients; it also ... ANUG is an opportunistic infection that occurs on a background of impaired local or systemic host defenses. The predisposing ...
Pathogenic fungus
Studies have shown that hosts with higher levels of immune response cells such as monocytes/macrophages, dendritic cells, and ... Abnormal over-growth of this fungus can occur, particularly in immunocompromised individuals. C. albicans has a parasexual ... It can cause potentially lethal invasive infection in immunocompromised individuals. A. fumigatus has a fully functional sexual ... gattii is endemic to tropical parts of the continent of Africa and Australia and can cause disease in non-immunocompromised ...
Primary effusion lymphoma
... an analog of host cell cyclin, which binds RB to increase these cells' proliferation; 3) vFLIP, which inhibits host cell's ... PEL typically occurs in individuals who are immunocompromised, i.e., individuals whose immune system is weakened and therefore ... K1 protein which promotes the malignancy of host cells; 7) G-protein coupled receptor protein which promotes host cells' ... which inhibits host cells' p53 protein thereby reducing these cells' apoptosis (i.e. programmed cell death) response to injury ...
Hospital-acquired infection
See Universal precautions and Transmission-based precautions.) Because agent and host factors are more difficult to control, ... The spread of nosocomial infections, among immunocompromised patients is connected with health care workers' hand contamination ...
Opportunistic infection
... one species of which can cause microsporidiosis in immunocompromised human hosts. Pneumocystis jirovecii (formerly known as ... Doitsh G, Greene WC (March 2016). "Dissecting How CD4 T Cells Are Lost During HIV Infection". Cell Host & Microbe. 19 (3): 280- ... healthy individuals but lead to more serious illness when given the opportunity to take advantage of an immunocompromised host ... Many of these pathogens do not necessarily cause disease in a healthy host that has a non-compromised immune system, and can, ...
Caliciviridae
Entry into the host cell is achieved by attachment to host receptors, which mediate endocytosis. Replication follows the ... Most calicivirus infections do not require medical intervention, but those who are immunocompromised may need to be ... Vertebrates serve as the natural host. Transmission routes are fecal-oral. Calicivirus infections commonly cause moderate to ... and they have a very narrow host range and no suitable animal model. However, the recent application of modern genomic ...
Vaccine hesitancy
An immunocompromised woman in Washington State was infected and later died of pneumonia due to measles. By July 2016, a three- ... The natural immunity against HPV is especially weak, as the virus uses various tactics to evade the host immune system. Many ... immunocompromised, or have severe allergies to the ingredients in the vaccine. The outcome for people with compromised immune ...
Mycotypha microspora
Mucormycosis is highly susceptible in immunocompromised patients, and can mainly infect the body at pulmonary, rhinocerebral, ... host receptors in endothelial cells. Tissue necrosis blocks the entry of antifungals to infected sites, therefore preventing ... "Horizontal transmission of the microbial symbionts Enterobacter cloacae and Mycotypha microspora to their firebrat host". ...
Multiple organ dysfunction syndrome
Old age is a risk factor in and of itself, and immunocompromised patients, such as with cancer or AIDS or a transplant, are at ... and confers host susceptibility to sepsis and MODS in these patients. For many years, some patients were loosely classified as ...
Timeline of the COVID-19 pandemic in Quebec
August 22 - Fifth doses become available to those aged 60 and up and to people aged 12 and up who are immunocompromised. August ... Lau, Rachel (May 19, 2021). "Circuit Gilles Villeneuve to host bike, drive-thru COVID-19 vaccination clinic". CTV News. ... and immunocompromised people. Anyone eligible can book their appointment once at least three months have elapsed since they ...
The Art of Elysium
jewelry preview party, hosted by actors Zoë Kravitz and Riley Keough, was held at The Art of Elysium's Elysium Art Salons in ... A socially distanced installation featuring the work of immunocompromised artist Torie Zalben. Bourn Kind: The Tiny Kindness ... "Riley Keough and Zoë Kravitz host Tiffany & Co. HardWear collection party in L.A." Los Angeles Times. 27 April 2017. Retrieved ...
Zoonosis
Even in a scenario with weak climatic changes, there will be 15,000 spillover of viruses to new hosts in the next decades. The ... Cattle are an important reservoir of cryptosporidiosis, which mainly affects the immunocompromised. Reports have shown mink can ... The term is from Greek: ζῷον zoon "animal" and νόσος nosos "sickness". Host genetics plays an important role in determining ... Because they depend on the human host for part of their life-cycle, diseases such as African schistosomiasis, river blindness, ...
Toxoplasmic chorioretinitis
Corticosteroids should not be used without concurrent antibiotic treatment or in immunocompromised patients due to the risk of ... promoted by this climatic condition concern both the parasite survival in the soil as well as a putative effect on the host ...
Staphylococcus hyicus
These virulence factors in combination with other factors like age, being immunocompromised, genetic susceptibility, trauma ( ... surface fibronectin-binding proteins for adhesion and production of staphylokinase and lipase to evade host defences. ...
Isospora
In 2005, all former Isospora species that infect mammalian hosts were reclassified as members of the genus Cystoisospora, a ... It is responsible for the condition isosporiasis, which causes acute, non-bloody diarrhoea in immunocompromised individuals. At ...
Human coronavirus OC43
Lim, Yvonne Xinyi; Ng, Yan Ling; Tam, James P.; Liu, Ding Xiang (2016-07-25). "Human Coronaviruses: A Review of Virus-Host ... and immunocompromised individuals such as those undergoing chemotherapy and those with HIV/AIDS. If HCoV-OC43 was indeed the ... The infecting coronavirus is an enveloped, positive-sense, single-stranded RNA virus that enters its host cell by binding to ... then passed through cattle as intermediate hosts. A deletion from BCoV to HCoV-OC43 may have taken place for the interspecies ...
Miranda Rosin
After hosting town hall forums across Alberta, the panel's suggestions pushed for more authority to create its own services and ... which at the time was limited to immunocompromised individuals and adults who were at least 40 years old. More vaccines were ...
Browsing by Subject "Immunocompromised Host"
Tula Hantavirus Infection in Immunocompromised Host, Czech Republic - Volume 19, Number 11-November 2013 - Emerging Infectious...
Zelená H, Mrázek J, Kuhn T. Tula Hantavirus Infection in Immunocompromised Host, Czech Republic. Emerging Infectious Diseases. ... Zelená H, Mrázek J, Kuhn T. Tula Hantavirus Infection in Immunocompromised Host, Czech Republic. Emerg Infect Dis. 2013;19(11): ... Zelená, H., Mrázek, J., & Kuhn, T. (2013). Tula Hantavirus Infection in Immunocompromised Host, Czech Republic. Emerging ... Tula Hantavirus Infection in Immunocompromised Host, Czech Republic. Volume 19, Number 11-November 2013 ...
International Immunocompromised Host Society - 17th Symposium Photo Album
Saudi Journal of Kidney Diseases and Transplantation (SJKDT)- Infection Control and the Immunocompromised Host : Download PDF
Respiratory viral infections in immunocompetent and immunocompromised persons
Immunocompromised Host* * Incidence * Neoplasms / complications * Respiratory Tract Infections / epidemiology * Respiratory ... Respiratory viral infections in immunocompetent and immunocompromised persons Am J Med. 1997 Mar 17;102(3A):2-9; discussion 25- ... This has recently been emphasized for immunocompromised persons. At the M.D. Anderson Cancer Center (MDACC), infection ...
Pneumonia in Immunocompromised Patients: Overview, Causes of Pneumonia, HIV/AIDS
... like the non-immunocompromised host, involves infection and inflammation of the lower respiratory tract. Despite recent overall ... How is pneumonia characterized in immunocompromised patients?. Which immunocompromised host groups are at highest risk for ... Pneumonia in the immunocompromised host is a complex infection and inflammation of the lower respiratory tract, complicated by ... Diffuse pulmonary infiltrates in the immunocompromised host. Clin Chest Med. 1990 Mar. 11(1):55-64. [QxMD MEDLINE Link]. ...
Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices...
IDSA Guidance for Vaccination of Immunocompromised Hosts. *2013 IDSA Clinical Practice Guideline for Vaccination of the ... Persons who are immunocompromised due to any cause (including but not limited to immunosuppression caused by medications or ... Immunocompromised states comprise a heterogeneous range of conditions with varying risks for severe infections. In many ... Immunocompromised Persons. ACIP recommends that persons with immunocompromising conditions (including but not limited to ...
IMSEAR at SEARO: Pulmonary infections in the immunocompromised host.
Browsing Medical Services by Subject "Immunocompromised Host"
Role of bronchoalveolar lavage in immunocompromised patients with pneumonia treated with a broad spectrum antibiotic and...
1985) Pulmonary disease in the immunocompromised host. Mayo Clin Proc 60:473-487, . ... supplying important information in immunocompromised patients as well as in immunocompromised patients receiving BSAR. ... Seventy one immunocompromised patients were allocated to group A (neutrophil granulocyte count less than 1000/μl) and 24 to ... 1984) Bronchoalveolar lavage in diagnosis of diffuse pulmonary infiltrates in the immunosuppressed host. Ann Intern Med 101:1-7 ...
Details for: Infections in the immunocompromised host-pathogenesis prevention and therapy : › WHO HQ Library catalog
By: (1st: International Symposium on Infections in the Immunocompromised Host (1st: 1980: Veldhoven, Netherlands)Contributor(s ... Infections in the immunocompromised host-pathogenesis prevention and therapy : proceedings of the First International Symposium ... on Infections in the Immunocompromised Host held in Veldhoven, The Netherlands, 1-5 June 1980 / editors, Jan Verhoef, Phillip K ...
Pneumonia - weakened immune system: MedlinePlus Medical Encyclopedia
Infections in the immunocompromised host: general principles. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and ... Approach to fever and suspected infection in the immunocompromised host. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine ... Pneumonia in immunodeficient patient; Pneumonia - immunocompromised host; Cancer - pneumonia; Chemotherapy - pneumonia; HIV - ... The immunocompromised patient. In: Walls RM, Hockberger RS, Gausche-Hill M, eds. Rosens Emergency Medicine: Concepts and ...
Russian theorists will benefit British physics
Evaluating Patients for Smallpox: Acute, Generalized Vesicular or Pustular Rash Illness Protocol | Smallpox | CDC
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Tula Hantavirus Infection in Immunocompromised Host, Czech Republic - Volume 19, Number 11-November 2013 - Emerging Infectious...
Zelená H, Mrázek J, Kuhn T. Tula Hantavirus Infection in Immunocompromised Host, Czech Republic. Emerging Infectious Diseases. ... Zelená H, Mrázek J, Kuhn T. Tula Hantavirus Infection in Immunocompromised Host, Czech Republic. Emerg Infect Dis. 2013;19(11): ... Zelená, H., Mrázek, J., & Kuhn, T. (2013). Tula Hantavirus Infection in Immunocompromised Host, Czech Republic. Emerging ... Tula Hantavirus Infection in Immunocompromised Host, Czech Republic. Volume 19, Number 11-November 2013 ...
Acute hypoxemic respiratory failure in immunocompromised patients: the Efraim multinational prospective cohort study<...
Immunocompromised Host Medicine & Life Sciences 100% * Artificial Respiration Medicine & Life Sciences 89% ... Background: In immunocompromised patients with acute hypoxemic respiratory failure (ARF), initial management aims primarily to ... abstract = "Background: In immunocompromised patients with acute hypoxemic respiratory failure (ARF), initial management aims ... The primary aim of this group is to improve and standardize practices in the management of critically ill immunocompromised ...
Leiomyosarcoma Cancer: Diagnosis, Treatment, Research & Support
Leiomyosarcoma in the Immunocompromised Host. Since the 1970s there have been a number of cases of leiomyosarcoma reported in ... Leiomyosarcoma in the Immunocompromised Host. Little is known about the specific prognostic implications of this rare entity, ... 6 There appears to be a relationship between these immunocompromised patients and super-infection with Epstein-Barr virus (EBV ... immunocompromised patients having undergone transplantation and treated with immunosuppressive regimens.15 More recently, there ...
Adenovirus: Background, Pathophysiology, Epidemiology
Echavarría M. Adenoviruses in immunocompromised hosts. Clin Microbiol Rev. 2008 Oct. 21(4):704-15. [QxMD MEDLINE Link]. [Full ... The prognosis of adenovirus infection is generally good in immunocompetent hosts, but mortality rates may be as high as 70% in ... An extremely hardy virus, adenovirus is ubiquitous in human and animal populations, survives long periods outside a host, and ... During oncogenesis, the replication cycle is truncated, and adenoviral DNA is then integrated into the host cells DNA. ...
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Acute Rhinosinusitis Empiric Therapy: Empiric Therapy Regimens
Pathogen Safety Data Sheets: Infectious Substances - Epstein-Barr virus - Canada.ca
Diseases in immunocompromised hosts: In AIDS patients or other immunosuppressed patients, many EBV-associated diseases may ... Survival outside host: Unknown. Section V: First aid and medical. Surveillance: Monitor for clinical symptomsFootnote 4. Direct ... Diseases in immunocompetent hosts. Infectious Mononucleosis (IM): IM is an acute, self limiting febrile illness in young adults ... Other malignant diseases in immunocompetent hosts include various B-cell or T-cell lymphomas, and epithelial or mesenchymal ...
Encephalitis - Symptoms, diagnosis and treatment | BMJ Best Practice
Plotkin's Vaccines - 7th Edition
Recurrent Uncomplicated Urinary Tract Infections in Women: AUA/CUA/SUFU Guideline (2022) - American Urological Association
... an immunocompromised host, or infection with multi-drug resistant (MDR) bacteria. In this guideline, the term UTI will refer to ... Depletion or alteration of the normal host microbiome and host innate barriers and innate immune system may lead to development ... Modulation of the host response to bacterial infection is a key dynamic for which limited information currently exists. ... Urine culture results, even those from extended quantitative urine culture techniques, do not reflect any aspect of the host ...
WEBVTT
These conditions were discussed in the section on immunocompromised hosts. 79 00:13:28.770 00:13:42.690 Lisa Grohskopf, MD ... Find a team is hosting several webinars for interested in participating providers and the dates are shown. Next slide. 254 00: ... to visit emergency CDC dot Govt forward slash coca to get more details about this Coca Cola and others as we intend to host ...
One Year of SARS-CoV-2 Evolution | Lab Manager
A number of SARS-CoV-2 variants have emerged from immunocompromised hosts, research has identified ... A number of SARS-CoV-2 variants have emerged from immunocompromised hosts, research has identified. Apr 21, 2021,5 min read. ... A number of SARS-CoV-2 variants have emerged from immunocompromised hosts, research has identified. It is thought that variants ... Persistent infections in immunocompromised people could cause the virus to mutate more frequently because the persons immune ...
Infectious Diseases Education & Training
Chronic Invasive Aspergillosis caused by Aspergillus viridinutans - Volume 15, Number 8-August 2009 - Emerging Infectious...
Unusual bone marrow manifestations of parvovirus B19 infection in immunocompromised patients<...
Immunocompromised Host Medicine & Life Sciences 74% * Parvoviridae Infections Medicine & Life Sciences 71% ... Unusual bone marrow manifestations of parvovirus B19 infection in immunocompromised patients. In: Human pathology. 2000 ; Vol. ... Unusual bone marrow manifestations of parvovirus B19 infection in immunocompromised patients. Terri W. Crook, Beverly Barton ... Unusual bone marrow manifestations of parvovirus B19 infection in immunocompromised patients. Human pathology. 2000;31(2):161- ...
Infections in immunocompromised hostsAcuteVaccinationSeverely immunocompromisedRespiratoryPneumoniaComplicationsMortalityPreventionFungalVaccinePathogensViral infectionsPregnant womenDiseasesInvasive disease2021AspergillusCancerInfantsImmunocompetent hostsPatientSevereThriveHumansPersonsCandidaTransplantTherapeuticPeopleFungusVariantsIndividualsRiskEndemicMice2017EvolutionaryFavorImmuneVirusMedicineFindings
Infections in immunocompromised hosts3
- My interest in viral infections in immunocompromised hosts stems from my experiences as a clinician, where I witnessed the impact of respiratory viral infections in vulnerable populations. (seattlechildrens.org)
- Our work focuses on two pathogens, Candida albicans and Aspergillus fumigatus , both of which cause fatal infections in immunocompromised hosts. (mcgill.ca)
- and immunomodulatory agents for treating underlying diseases from cancer to rheumatoid arthritishas contributed to the increase in fungal infections in immunocompromised hosts. (cdc.gov)
Acute3
- Pneumonia in immunocompromised is often complicated by superinfection, drug toxicity, empyema , sepsis, pneumothorax , and acute respiratory distress syndrome (ARDS) . (medscape.com)
- We have investigated the diagnostic value of bronchoalveolar lavage (BAL) in 95 immunocompromised patients with haematological disorders and clinical signs of acute pneumonia, comparing BAL with non-invasive procedures such as surveillance cultures at different sites. (bmj.com)
- Background: In immunocompromised patients with acute hypoxemic respiratory failure (ARF), initial management aims primarily to avoid invasive mechanical ventilation (IMV). (elsevier.com)
Vaccination3
- For vaccination of persons with altered immunocompetence, various references, including ACIP's general best practices (4), Chapter 5 of the CDC Yellow Book (5), and the Infectious Diseases Society of America's 2013 IDSA Clinical Practice Guideline for Vaccination of the Immunocompromised Host (6), can be consulted for additional information about the degree of immune suppression associated with different medical conditions and treatments. (cdc.gov)
- The risk of deferring vaccination, and thus not mitigating the increased risk for shingles and related complications in immunocompromised patients, should be weighed against a possible diminished response to RZV if given during periods of more intense immunosuppression. (cdc.gov)
- Even after vaccination, severely immunocompromised people face substantial risk. (slate.com)
Severely immunocompromised1
- In severely immunocompromised individuals, the typical presentation of TB becomes less frequent. (medscape.com)
Respiratory4
- Pneumonia in the immunocompromised host is a complex infection and inflammation of the lower respiratory tract, complicated by widespread multi-drug antibiotic resistance, and aided by medical advances such as improvements in diagnostic measures and immunosuppressive agents. (medscape.com)
- Comparison of Respiratory Pathogen Detection in Upper versus Lower Respiratory Tract Samples Using the BioFire FilmArray Respiratory Panel in the Immunocompromised Host. (mayoclinic.org)
- Although the common respiratory virus normally causes coldlike symptoms that typically resolve in a week or so, RSV can be severe in infants and elderly people , according to the CDC, as well as in those who are immunocompromised. (yahoo.com)
- We had nothing to offer it," meaning that respiratory viruses, including RSV, didn't have as many hosts to infect while people stayed home for the most part. (yahoo.com)
Pneumonia6
- Though overall patient survival has increased, pneumonia is both the most common invasive infection in immunocompromised patients and continues to carry a high mortality and morbidity rate. (medscape.com)
- There are four major groups of pathogens responsible for pneumonia in immunocompromised patients. (medscape.com)
- BACKGROUND In a retrospective study the value of bronchoalveolar lavage (BAL) in the diagnosis of pneumonia was investigated in 95 immunocompromised patients suffering from haematological disorders and receiving a regimen of broad spectrum antibiotics and antifungal agents (BSAR). (bmj.com)
- BAL is a relatively safe procedure in the diagnosis of pneumonia, supplying important information in immunocompromised patients as well as in immunocompromised patients receiving BSAR. (bmj.com)
- This type of disease is called "pneumonia in an immunocompromised host. (medlineplus.gov)
- Pneumonia is classified into community-acquired pneumonia (CAP), hospital-acquired pneumonia (HAP) and pneumonia in the immunocompromised. (bvsalud.org)
Complications2
- however it can lead to severe complications and mortality both in immunocompromised and immunocompetent patients as well. (biomedcentral.com)
- La prise en charge thérapeutique doit être instaurée pour réduire le taux de mortalité et éviter les complications liées á ces infections. (bvsalud.org)
Mortality2
- Despite these positive attributes, soil-borne fungi can have significant negative impacts on human health, causing life-threatening disseminated infections in the immunocompromised host, with disproportionately high rates of mortality and morbidity. (exeter.ac.uk)
- Invasive Mucorales infections (IMI) lead to significant morbidity and mortality in immunocompromised hosts. (biomedcentral.com)
Prevention4
- Infections in the immunocompromised host-pathogenesis prevention and therapy : proceedings of the First International Symposium on Infections in the Immunocompromised Host held in Veldhoven, The Netherlands, 1-5 June 1980 / editors, Jan Verhoef, Phillip K. Peterson, Paul G. Quie. (who.int)
- Data generated in this research will provide the critical basis to develop rational prevention and treatment strategies for immunocompromised patients. (seattlechildrens.org)
- Practical guidance with supporting evidence is offered to the medical provider regarding infection prevention and control for the hospitalized immunocompromised pediatric patient. (elsevier.com)
- The study of AZD1222 Vaccine for the Prevention of COVID-19 in Immunocompromised Adults. (who.int)
Fungal1
- The adherence of these organisms to host tissues, especially vascular endothelial cells is a critical step in the pathogenesis of infection, and our work has begun to elucidate the fungal adhesins involved in this process and the genetic pathways controlling their expression. (mcgill.ca)
Vaccine2
- CDC's new recommendations allow an additional updated (bivalent) vaccine dose for adults ages 65 years and older and additional doses for people who are immunocompromised. (cdc.gov)
- So for my families, I will continue to recommend vaccine - or masking, especially for children who are less than 5 years old, and then for my immunocompromised children that I take care of. (usf.edu)
Pathogens1
- Scedosporium apiospermum is a well known causative agent of mycetoma (tumour-like swellings with draining sinuses), but this species and the pathogen Lomentospora prolificans (formerly Scedosporium prolificans ) have also recently emerged as significant invasive pathogens, particularly of immunocompromised patients, and now account for ~25% of non- Aspergillus infections in high risk patient groups. (exeter.ac.uk)
Viral infections1
- Dr. Alpana Waghmare studies viral infections in immunocompromised patients. (seattlechildrens.org)
Pregnant women2
- This guideline does not apply to pregnant women, patients who are immunocompromised, those with anatomic or functional abnormalities of the urinary tract, women with rUTIs due to self-catheterization or indwelling catheters or those exhibiting signs or symptoms of systemic bacteremia, such as fever and flank pain. (auanet.org)
- Even individuals not able to receive certain vaccines such as pregnant women, infants, and immunocompromised persons get some protection from this phenomenon, known as community (or herd) immunity . (cdc.gov)
Diseases6
- Many benign and malignant diseases, however, have been associated with Epstein- Barr virus in both immunocompetent and immunocompromised patients Footnote 1 Footnote 2 Footnote 3 Footnote 4 Footnote 5 Footnote 6 Footnote 7 Footnote 8 Footnote 9 . (canada.ca)
- Other malignant diseases in immunocompetent hosts include various B-cell or T-cell lymphomas, and epithelial or mesenchymal carcinomas such as classical Hodgkin's lymphoma and nasopharyngeal carcinoma Footnote 6 Footnote 7 Footnote 10 . (canada.ca)
- Similar reports have found evidence of within-host viral evolution of the SARS-CoV-2 virus in transplant recipients and in patients suffering from autoimmune diseases requiring aggressive immunosuppression. (slate.com)
- Zoonotic diseases risk for immunocompromised and other high-risk clients and staff promoting safe pet ownership and contact. (scielo.br)
- The virus causes PML and other diseases only in cases of immunodeficiency, as in AIDS or during treatment with drugs intended to induce MW polyomavirus (MWPyV, also known as Human polyomavirus 10 and briefly as MXPyV) is a virus of the polyomavirus family that infects human hosts.It was discovered in 2012 and reported independently by several research groups. (web.app)
- Most infections Infections Invasion of the host organism by microorganisms or their toxins or by parasites that can cause pathological conditions or diseases. (lecturio.com)
Invasive disease1
- Listeria monocytogenes is responsible for gastroenteritis in healthy individuals and for a severe invasive disease in immunocompromised patients. (pasteur.fr)
20211
- La información en esta página debería ser considerada como ejemplos de información de antecedentes para la temporada de influenza 2021-2022 para la práctica médica respecto del uso de medicamentos antivirales contra la influenza. (cdc.gov)
Aspergillus2
Cancer2
Infants1
- For infants and immunocompromised patients infected with WNV, the fatality rate is even higher. (loinc.org)
Immunocompetent hosts1
- Clinical illness is mild for all immunocompetent hosts although disease severity increases with age. (biomedcentral.com)
Patient2
- We report molecular evidence of Tula hantavirus as an etiologic agent of pulmonary-renal syndrome in an immunocompromised patient. (cdc.gov)
- The immunocompromised patient. (medlineplus.gov)
Severe3
- Given the large populations of feral pigeons with PPMV-1 infection in cities, increasing urbanization, and a higher proportion of immunocompromised individuals, the risk of severe human PPMV-1 infections May increase. (eur.nl)
- Irrespective of the cause, immunocompromised individuals present both a higher risk of infection and greater potential for more severe clinical course 4 4. (scielo.br)
- patients come to Thrive who are immunocompromised or at higher risk for severe disease from COVID-19. (thrive-acupuncture.com)
Thrive1
- For a disease to spread it needs to have viable hosts (places to thrive and reproduce). (cdc.gov)
Humans1
- In such scenarios, humans are often exposed to potential reservoir animals or animal hosts in various situations, including workplace, diet, and household. (scielo.br)
Persons2
Candida2
- In immunocompromised patients, Pseudomonas aeruginosa and Candida have been named. (nih.gov)
- Candida species are known to causeserious infections in immunocompromised patients but uncommon cases have been reported in immunocompetent individuals regardless of the harmless co-existence of the fungi with the host. (bvsalud.org)
Transplant1
- Participants with autologous (up to 6 months after transplantation) or allogeneic stem cell transplant who are immunosuppressed, with no evidence of active graft-versus host disease, at least one month after the procedure. (who.int)
Therapeutic2
- We determined whether the BAL findings are associated with the therapeutic outcome for immunocompromised patients routinely receiving a broad spectrum antibiotic and antifungal regimen (BSAR). (bmj.com)
- The number of immunocompromised patients is increasing due to factors such as increase in number of transplants and therapeutic approaches with biological and chemotherapeutic agents. (scielo.br)
People4
- Persistent infections in immunocompromised people could cause the virus to mutate more frequently because the person's immune system cannot clear the virus as quickly as the immune system of a healthy person. (labmanager.com)
- JC virus is responsible for causing progressive multifocal leukoencephalopathy (PMLE) in immunocompromised people. (web.app)
- He further expressed his gratitude to the government and people of Mozambique for hosting the fifty-fifth session of the WHO Regional Committee for Africa. (who.int)
- As a founding party to the International Federation of Black Prides, ITLA annually hosts upwards of 100,000 Black queer people in Atlanta, Georgia-comandeering almost every major club, the entire metro area, and, the city's heartbeat, Piedmont park. (kingofreads.com)
Fungus1
- However, the fungus can also invade the host via lung tissue resulting in a disease known as invasive aspergillosis. (exeter.ac.uk)
Variants1
- Coronavirus variants: what pleas to protect the immunocompromised keep missing. (slate.com)
Individuals1
- However, some polyomaviruses are associated with human disease, particularly in immunocompromised individuals. (web.app)
Risk3
- I propose that viral and host factors may serve as biomarkers for disease severity and can provide needed risk stratification and management tools. (seattlechildrens.org)
- If not used carefully, antiviral and antibody therapies-which many experts believe are even more critical in curing COVID-19 in immunocompromised hosts-risk worsening the problem by exerting evolutionary pressure that selects for resilient strains. (slate.com)
- Unfortunately few, if any, high-quality studies exist that doctors can use as guidance for maximizing the benefit of these therapies to immunocompromised patients while minimizing public health risk . (slate.com)
Endemic1
- An extremely hardy virus, adenovirus is ubiquitous in human and animal populations, survives long periods outside a host, and is endemic throughout the year. (medscape.com)
Mice2
- Here, we demonstrate that Listeriolysin S (LLS), a virulence factor only present in a subset of lineage I strains, is a bacteriocin highly expressed in the intestine of orally infected mice that alters the host intestinal microbiota and promotes intestinal colonization by L. monocytogenes, as well as deeper organ infection. (pasteur.fr)
- We will study biodistribution and transduction of Ad5 and Ad5 ablated for FX binding in both immunocompetent and immunocompromised mice. (ukri.org)
20171
- Of the polyomaviruses cataloged as of 2017, a total of 14 were known with human hosts. (web.app)
Evolutionary1
- Whether an evolutionary offshoot ultimately takes hold is a product of viral fitness, selection pressures, and host susceptibility. (slate.com)
Favor2
- Bacteriocin from epidemic Listeria strains alters the host intestinal microbiota to favor infection. (pasteur.fr)
- For researchers at the Smithsonian Tropical Research Institute (STRI) and INDICASAT AIP, some of these invisible skin dwellers could be doing their hosts a favor, by producing metabolites that inhibit the growth of fungi and other bacteria. (dicyt.com)
Immune3
- This protein allows the virus to enter host cells and is the main target of the immune system, including immunity generated by all current SARS-CoV-2 vaccines. (labmanager.com)
- Other groups have also suggested that either the host coats the virus with FX in order to help the immune system recognise it and remove it, while others have suggested that the virus itself 'picks up' the coagulation factor to protect itself from the immune system. (ukri.org)
- However, these natural killer cells play an important role in immune function and may help patients with immunocompromised stay healthy. (restorbio.com)
Virus5
- Additionally, specific genes can be inserted into the virus that then can repair defective metabolic, enzymatic, or synthetic pathways in the host. (medscape.com)
- This mutation is believed to be the result of infection of an immunocompromised individual and may contribute to the virus being more contagious. (labmanager.com)
- Actualización sobre el virus la influenza aviar A (H5N1) en los seres humanos. (cdc.gov)
- Birds are the preferred host of WNV, and the American robin is an important amplifier host since it develops enough virus in its serum to infect feeding mosquitoes. (loinc.org)
- Host interactions govern infectivity of the virus, and subsequent responses dictate efficiency of gene therapy and safety. (ukri.org)
Medicine1
- Welcome to another episode of Medicine and the Machine with my co-host, Eric Topol. (medscape.com)
Findings1
- The findings of erythroid maturation and abundant viral inclusions in these immunocompromised patients is consistent with the hypothesis that failure to produce effective IgG parvovirus neutralizing antibodies may lead to persistent infection through viral tolerance that allows erythroid development of infected cells past the pronormoblast stage. (umn.edu)