Immunization
Immunization Programs
Immunization Schedule
Immunization, Secondary
Immunization, Passive
Vaccination
Vaccines
Vaccines, Synthetic
Vaccines, DNA
Antibody Formation
Immunoglobulin G
Adjuvants, Immunologic
Viral Vaccines
Measles Vaccine
Immunity, Mucosal
Influenza Vaccines
Tetanus
Immunoglobulin A
Diphtheria-Tetanus-Pertussis Vaccine
Vaccines, Attenuated
Vaccines, Inactivated
Measles
Hepatitis B Vaccines
Diphtheria Toxoid
Immunity, Cellular
Injections, Intramuscular
Immunoglobulin A, Secretory
Immunity, Maternally-Acquired
Antibody Specificity
Pertussis Vaccine
AIDS Vaccines
Cholera Toxin
Injections, Intradermal
Immunity, Active
Enzyme-Linked Immunosorbent Assay
Freund's Adjuvant
Mumps Vaccine
T-Lymphocytes
Cross Reactions
Rubella Vaccine
Vaccines, Subunit
Vaccines, Conjugate
Diphtheria
Poliomyelitis
Antibodies
Toxoids
Biolistics
CD8-Positive T-Lymphocytes
Protozoan Vaccines
Immunity, Humoral
T-Lymphocytes, Cytotoxic
Lymphocyte Activation
Neutralization Tests
Interferon-gamma
Haemophilus Vaccines
Pneumococcal Vaccines
Cancer Vaccines
Malaria Vaccines
Dose-Response Relationship, Immunologic
Injections, Subcutaneous
Alum Compounds
Hypersensitivity, Delayed
Poliovirus Vaccine, Oral
Immunologic Memory
Whooping Cough
Immune Sera
CD4-Positive T-Lymphocytes
Antibody-Producing Cells
Viral Hepatitis Vaccines
Rabbits
Immunoglobulin M
Epitopes, T-Lymphocyte
Immunity
Disease Models, Animal
Poliovirus Vaccines
Administration, Rectal
Genetic Vectors
B-Lymphocytes
Vaccinia virus
Immunoglobulin Isotypes
Antitoxins
Influenza, Human
Contraception, Immunologic
Immunotherapy, Active
Diphtheria-Tetanus-acellular Pertussis Vaccines
Antibodies, Neutralizing
Meningococcal Vaccines
BCG Vaccine
Th1 Cells
Antigens, Protozoan
Lymph Nodes
Peptide Fragments
Molecular Sequence Data
Injections, Intraperitoneal
Rubella
Cytokines
Haptens
Drug Administration Routes
Dendritic Cells
Epitopes, B-Lymphocyte
Amino Acid Sequence
Immune Tolerance
Administration, Mucosal
Mucous Membrane
Cholera Vaccines
Antigens, Neoplasm
Antibodies, Anti-Idiotypic
Mice, Transgenic
Autoimmune Diseases
Mice, Inbred Strains
Mumps
Autoantibodies
Administration, Cutaneous
Nasal Mucosa
Chickenpox Vaccine
Rabies Vaccines
Antibody Affinity
Macaca mulatta
Advisory Committees
Communicable Disease Control
Adoptive Transfer
Fungal Vaccines
Hepatitis A Vaccines
Typhoid-Paratyphoid Vaccines
Immunotherapy
Hemagglutination Inhibition Tests
Cytotoxicity, Immunologic
Immunoglobulin Idiotypes
Autoantigens
Viral Envelope Proteins
Reminder Systems
Epitope Mapping
Bacterial Toxins
Th2 Cells
Hepatitis B
Bacterial Capsules
Immunodominant Epitopes
SAIDS Vaccines
Hepatitis B Surface Antigens
T-Lymphocytes, Helper-Inducer
Immunoglobulins
Haemophilus influenzae type b
Streptococcus pneumoniae
Aluminum Hydroxide
Hepatitis B Antibodies
Recombinant Fusion Proteins
Mice, Knockout
Peptides
Plasmids
ISCOMs
Smallpox Vaccine
Sporozoites
gamma-Globulins
Interleukin-4
Bacterial Outer Membrane Proteins
Saliva
Papillomavirus Vaccines
Diphtheria-Tetanus Vaccine
Suppression of Moloney sarcoma virus immunity following sensitization with attenuated virus. (1/7909)
Murine sarcoma virus (Moloney strain) (MSV-M)-induced tumors are unusual in that they regularly appear less than 2 weeks after virus inoculation, progress for 1 to 2 weeks, and are rejected by normal adult BALB/c mice. Rejectio leaves the animals immune to tumor induction. In the present study, presensitization of normal adult BALB/c mice with attenuated MSV-M resulted in an altered pattern of tumor immunity. Injection of active MSV-M into the presensitized animals resulted in tumor induction and rejection similar to that observed in normal animals, but rejection failed to produce protection against the secondary inoculation with MSV-M. After the second inoculation with active MSV-M, tumors appeared and progressed but ultimately were rejected. Over 80% of the mice died, 25% after the primary challenge and the remainder after the secondary challenge. At death, all mice had histological evidence of leukemia which was the probable cause of death. The animals that died following the secondary challenge also had evidence of disseminated MSV-M. Solid tumor nodules were found in skeletal muscle distant from the original site of inoculation, and active MSV-M was isolated from spleen and lungs. The possibility that the results were produced by specific suppression of MSV-Moloney leukemia virus immunity is discussed. (+info)Transcutaneous immunization with bacterial ADP-ribosylating exotoxins as antigens and adjuvants. (2/7909)
Transcutaneous immunization (TCI) is a new technique that uses the application of vaccine antigens in a solution on the skin to induce potent antibody responses without systemic or local toxicity. We have previously shown that cholera toxin (CT), a potent adjuvant for oral and nasal immunization, can induce both serum and mucosal immunoglobulin G (IgG) and IgA and protect against toxin-mediated mucosal disease when administered by the transcutaneous route. Additionally, CT acts as an adjuvant for coadministered antigens such as tetanus and diphtheria toxoids when applied to the skin. CT, a member of the bacterial ADP-ribosylating exotoxin (bARE) family, is most potent as an adjuvant when the A-B subunits are present and functional. We now show that TCI induces secondary antibody responses to coadministered antigens as well as to CT in response to boosting immunizations. IgG antibodies to coadministered antigens were also found in the stools and lung washes of immunized mice, suggesting that TCI may target mucosal pathogens. Mice immunized by the transcutaneous route with tetanus fragment C and CT developed anti-tetanus toxoid antibodies and were protected against systemic tetanus toxin challenge. We also show that bAREs, similarly organized as A-B subunits, as well as the B subunit of CT alone, induced antibody responses to themselves when given via TCI. Thus, TCI appears to induce potent, protective immune responses to both systemic and mucosal challenge and offers significant potential practical advantages for vaccine delivery. (+info)Zonula occludens toxin is a powerful mucosal adjuvant for intranasally delivered antigens. (3/7909)
Zonula occludens toxin (Zot) is produced by toxigenic strains of Vibrio cholerae and has the ability to reversibly alter intestinal epithelial tight junctions, allowing the passage of macromolecules through the mucosal barrier. In the present study, we investigated whether Zot could be exploited to deliver soluble antigens through the nasal mucosa for the induction of antigen-specific systemic and mucosal immune responses. Intranasal immunization of mice with ovalbumin (Ova) and recombinant Zot, either fused to the maltose-binding protein (MBP-Zot) or with a hexahistidine tag (His-Zot), induced anti-Ova serum immunoglobulin G (IgG) titers that were approximately 40-fold higher than those induced by immunization with antigen alone. Interestingly, Zot also stimulated high anti-Ova IgA titers in serum, as well as in vaginal and intestinal secretions. A comparison with Escherichia coli heat-labile enterotoxin (LT) revealed that the adjuvant activity of Zot was only sevenfold lower than that of LT. Moreover, Zot and LT induced similar patterns of Ova-specific IgG subclasses. The subtypes IgG1, IgG2a, and IgG2b were all stimulated, with a predominance of IgG1 and IgG2b. In conclusion, our results highlight Zot as a novel potent mucosal adjuvant of microbial origin. (+info)Noncompetitive expansion of cytotoxic T lymphocytes specific for different antigens during bacterial infection. (4/7909)
Listeria monocytogenes is an intracellular bacterium that elicits complex cytotoxic T-lymphocyte (CTL) responses in infected mice. The responses of CTL populations that differ in antigen specificity range in magnitude from large, dominant responses to small, subdominant responses. To test the hypothesis that dominant T-cell responses inhibit subdominant responses, we eliminated the two dominant epitopes of L. monocytogenes by anchor residue mutagenesis and measured the T-cell responses to the remaining subdominant epitopes. Surprisingly, the loss of dominant T-cell responses did not enhance subdominant responses. While mice immunized with bacteria lacking dominant epitopes developed L. monocytogenes-specific immunity, their ability to respond to dominant epitopes upon rechallenge with wild-type bacteria was markedly diminished. Recall responses in mice immunized with wild-type or epitope-deficient L. monocytogenes showed that antigen presentation during recall infection is sufficient for activating memory cells yet insufficient for optimal priming of naive T lymphocytes. Our findings suggest that T-cell priming to different epitopes during L. monocytogenes infection is not competitive. Rather, T-cell populations specific for different antigens but the same pathogen expand independently. (+info)Ovine MHC class II DRB1 alleles associated with resistance or susceptibility to development of bovine leukemia virus-induced ovine lymphoma. (5/7909)
For the further characterization of bovine leukemia virus (BLV)-induced leukemogenesis, we investigated the association between polymorphism of ovine leukocyte antigen (OLA)-DRB1 gene and tumor development after infection of sheep with BLV. We infected 28 sheep with BLV and cloned exon 2 of the OLA-DRB1 gene from asymptomatic animals and from animals with lymphoma Sequence analysis revealed that, among 12 healthy sheep without any evidence of tumor, ten (83.3%) carried DRB1 alleles encoding Arg-Lys (RK) at positions beta70/71 as compared with only 6 (37.5%) of the 16 sheep with lymphoma, which suggested that alleles encoding the RK motif might protect against development of tumors after infection by BLV. By contrast, alleles encoding Ser-Arg (SR) at positions beta70/71 were present at a significantly elevated frequency in sheep with lymphoma as compared with the healthy carriers, which indicated that OLA-DRB1 alleles encoding the SR motif might be positively related to susceptibility to tumor development. The two amino acids in these motifs line a pocket that accommodates the side chain of a bound peptide according to a model of the crystal structure of human leukocyte antigen (HLA)-DR1. To analyze immunoreactions of sheep with alleles that encoded RK or SR at beta70/71, we selected sheep with either the RK/SR genotypes or the SR/SR genotypes and immunized them with a mixture of multiple synthetic antigenic peptides that corresponded to T-helper, T-cytotoxic, and B-cell epitopes of the BLV envelope glycoprotein gp51. Two weeks after the last immunization, all of the sheep were challenged with BLV. Sheep with the RK/SR genotype produced neutralizing antibodies against BLV; they eliminated BLV completely within 28 weeks of the BLV challenge, and they gave strong lymphocyte-proliferative responses to the peptides used for immunization. Moreover, such animals did not develop lymphoma. By contrast, sheep with the SR/SR genotype continued to produce BLV throughout the experimental period and developed terminal disease. Our results indicate that the differences in immunoresponse were due to differences in major histocompatibility complex class II alleles and reflected the risk of BLV-induced leukemogenesis. In addition, it appears that susceptibility to tumor development may be determined to some extent by polymorphic residues binding to antigenic peptides directly within the binding cleft of the OLA-DR molecule. (+info)Immunosurveillance and the evaluation of national immunization programmes: a population-based approach. (6/7909)
Mass vaccination can change the epidemiological dynamics of infectious diseases. It may result in a limited persistence of natural and vaccine-induced immunity and a higher mean age of infection, which may lead to a greater risk of complications. The epidemiological situation should be monitored and immunosurveillance based on the assessment of specific antibodies against vaccine-preventable diseases in human serum is one of the tools. In order to estimate the immunity of the Dutch population reliably, a large-scale, population-based, collection of serum samples was established (8359 sera in a nation-wide sampling and 1589 sera from municipalities with low vaccine coverage). In contrast to collecting residual sera from laboratories, this approach gains extensive information by means of a questionnaire regarding the determinants of the immune status and the risk factors for the transmission of infectious diseases in general. The population-based approach gives a better guarantee that the data are representative than collecting sera from laboratories does. (+info)Rubella immunisation and contraception--a case for re-examining the policy of the Department of Health and Social Security. (7/7909)
Now that immunisation against rubella is available, it would at first sight seem reasonable to identify all potential mothers susceptible to this disease and immunise them. Preliminary screening, however, carried out in order to restrict vaccination to seronegative subjects, not only serves no useful purpose, but is counter-productive. (+info)Chlamydia infections and heart disease linked through antigenic mimicry. (8/7909)
Chlamydia infections are epidemiologically linked to human heart disease. A peptide from the murine heart muscle-specific alpha myosin heavy chain that has sequence homology to the 60-kilodalton cysteine-rich outer membrane proteins of Chlamydia pneumoniae, C. psittaci, and C. trachomatis was shown to induce autoimmune inflammatory heart disease in mice. Injection of the homologous Chlamydia peptides into mice also induced perivascular inflammation, fibrotic changes, and blood vessel occlusion in the heart, as well as triggering T and B cell reactivity to the homologous endogenous heart muscle-specific peptide. Chlamydia DNA functioned as an adjuvant in the triggering of peptide-induced inflammatory heart disease. Infection with C. trachomatis led to the production of autoantibodies to heart muscle-specific epitopes. Thus, Chlamydia-mediated heart disease is induced by antigenic mimicry of a heart muscle-specific protein. (+info)The symptoms of tetanus can develop anywhere from 3 days to 3 weeks after exposure to the bacteria, and they can include:
* Muscle stiffness and spasms, especially in the neck, jaw, and limbs
* Difficulty swallowing or speaking
* Fever and sweating
* Headache and fatigue
* Rigidity and spasticity of muscles
* Abdominal cramps and diarrhea
* In severe cases, tetanus can cause serious complications such as pneumonia, heart problems, and death.
Tetanus is diagnosed through a physical examination, medical history, and laboratory tests. Treatment typically involves administering antitoxin medication to neutralize the effects of the bacterial toxins, as well as providing supportive care such as pain management and wound care.
Prevention is key in avoiding tetanus, and this can be achieved through:
* Vaccination: Tetanus vaccines are available and recommended for individuals of all ages, especially for those who have open wounds or injuries.
* Proper wound care: Keeping wounds clean and covered can help prevent the entry of bacteria into the body.
* Avoiding risky behaviors: Avoiding activities that can cause injury, such as playing contact sports or engaging in dangerous hobbies, can reduce the risk of developing tetanus.
Overall, tetanus is a serious medical condition that requires prompt treatment and prevention measures to avoid complications and ensure a full recovery.
Measles is caused by a virus that is transmitted through the air when an infected person coughs or sneezes. The virus can also be spread through direct contact with an infected person's saliva or mucus.
The symptoms of measles usually appear about 10-14 days after exposure to the virus, and may include:
* Fever
* Cough
* Runny nose
* Red, watery eyes
* Small white spots inside the mouth (Koplik spots)
* A rash that starts on the head and spreads to the rest of the body
Measles can be diagnosed through a physical examination, laboratory tests, or by observing the characteristic rash. There is no specific treatment for measles, but it can be treated with over-the-counter medications such as acetaminophen or ibuprofen to relieve fever and pain.
Complications of measles can include:
* Ear infections
* Pneumonia
* Encephalitis (inflammation of the brain)
* Seizures
* Death (rare)
Measles is highly contagious and can spread easily through schools, workplaces, and other communities. Vaccination is the best way to prevent measles, and the Measles, Mumps, and Rubella (MMR) vaccine is recommended for all children and adults who have not been previously infected with the virus or vaccinated.
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The symptoms of diphtheria typically develop within 2-5 days after exposure and may include:
* Sore throat and difficulty swallowing
* Fever and chills
* Swollen and tender lymph nodes in the neck
* Difficulty breathing or shortness of breath
* Skin lesions or rashes
* Nerve damage, leading to weakness, paralysis, and other neurological symptoms.
If left untreated, diphtheria can lead to serious complications such as respiratory failure, heart failure, and death. Treatment typically involves antibiotics, which can help clear the infection and prevent further damage. In severe cases, hospitalization may be required to provide supportive care, such as mechanical ventilation or cardiac support.
Diphtheria is a vaccine-preventable disease, and immunization programs have been instrumental in reducing the incidence of this disease worldwide. However, outbreaks still occur in some areas, particularly among unvaccinated individuals or those living in areas with low vaccination coverage.
In addition to its clinical features, diphtheria has several key characteristics that are important to note:
* It is highly contagious and can be transmitted through respiratory droplets, close contact with an infected person, or by touching contaminated surfaces and objects.
* The bacteria can survive for weeks outside the body, making it a significant risk for transmission through fomites.
* Immunity to diphtheria is not lifelong, and booster doses of the vaccine are recommended every 10 years to maintain protection.
There are three main forms of poliomyelitis:
1. Non-paralytic polio, which causes symptoms such as fever, headache, and sore throat, but does not lead to paralysis.
2. Paralytic polio, which can cause partial or complete paralysis of the muscles in the limbs, trunk, and respiratory system. This form is more severe and can be fatal.
3. Post-polio syndrome, which occurs in some individuals years after they have recovered from a paralytic polio infection. It is characterized by new muscle weakness, pain, and fatigue.
Poliomyelitis was once a major public health problem worldwide, but widespread immunization campaigns have led to a significant decline in the number of cases. The World Health Organization (WHO) has set a goal of eradicating polio by 2018.
Treatment for poliomyelitis typically focuses on managing symptoms and supporting respiratory function. In severe cases, hospitalization may be necessary to provide intensive care, such as mechanical ventilation. Physical therapy and rehabilitation are also important in helping individuals recover from paralysis.
Prevention is key to controlling the spread of poliomyelitis. This includes vaccination with the oral poliovirus vaccine (OPV), which has been shown to be safe and effective in preventing polio. In addition, good hygiene practices, such as washing hands regularly, can help reduce the risk of transmission.
Examples of delayed hypersensitivity reactions include contact dermatitis (a skin reaction to an allergic substance), tuberculin reactivity (a reaction to the bacteria that cause tuberculosis), and sarcoidosis (a condition characterized by inflammation in various organs, including the lungs and lymph nodes).
Delayed hypersensitivity reactions are important in the diagnosis and management of allergic disorders and other immune-related conditions. They can be detected through a variety of tests, including skin prick testing, patch testing, and blood tests. Treatment for delayed hypersensitivity reactions depends on the underlying cause and may involve medications such as antihistamines, corticosteroids, or immunosuppressants.
Symptoms of whooping cough typically appear within 7-14 days after exposure and may include:
* Mild fever
* Runny nose
* Sneezing
* Dry, irritating cough that progresses to spasmodic, convulsive coughing fits
* Vomiting after coughing
* Apnea (pause in breathing)
In infants, the symptoms may be milder and include:
* Mild fever
* Lack of appetite
* Irritability
* Cyanosis (blue discoloration of the skin)
If left untreated, whooping cough can lead to serious complications such as pneumonia, seizures, and brain damage. Diagnosis is based on a combination of clinical findings, laboratory tests, and medical imaging. Treatment typically involves antibiotics and supportive care to manage symptoms and prevent complications.
Prevention measures include immunization with the pertussis vaccine, which is routinely given to infants and children in early childhood, as well as booster shots during adolescence and adulthood. Good hygiene practices, such as frequent handwashing and avoiding close contact with people who are sick, can also help prevent the spread of the disease.
1) They share similarities with humans: Many animal species share similar biological and physiological characteristics with humans, making them useful for studying human diseases. For example, mice and rats are often used to study diseases such as diabetes, heart disease, and cancer because they have similar metabolic and cardiovascular systems to humans.
2) They can be genetically manipulated: Animal disease models can be genetically engineered to develop specific diseases or to model human genetic disorders. This allows researchers to study the progression of the disease and test potential treatments in a controlled environment.
3) They can be used to test drugs and therapies: Before new drugs or therapies are tested in humans, they are often first tested in animal models of disease. This allows researchers to assess the safety and efficacy of the treatment before moving on to human clinical trials.
4) They can provide insights into disease mechanisms: Studying disease models in animals can provide valuable insights into the underlying mechanisms of a particular disease. This information can then be used to develop new treatments or improve existing ones.
5) Reduces the need for human testing: Using animal disease models reduces the need for human testing, which can be time-consuming, expensive, and ethically challenging. However, it is important to note that animal models are not perfect substitutes for human subjects, and results obtained from animal studies may not always translate to humans.
6) They can be used to study infectious diseases: Animal disease models can be used to study infectious diseases such as HIV, TB, and malaria. These models allow researchers to understand how the disease is transmitted, how it progresses, and how it responds to treatment.
7) They can be used to study complex diseases: Animal disease models can be used to study complex diseases such as cancer, diabetes, and heart disease. These models allow researchers to understand the underlying mechanisms of the disease and test potential treatments.
8) They are cost-effective: Animal disease models are often less expensive than human clinical trials, making them a cost-effective way to conduct research.
9) They can be used to study drug delivery: Animal disease models can be used to study drug delivery and pharmacokinetics, which is important for developing new drugs and drug delivery systems.
10) They can be used to study aging: Animal disease models can be used to study the aging process and age-related diseases such as Alzheimer's and Parkinson's. This allows researchers to understand how aging contributes to disease and develop potential treatments.
Symptoms of influenza include:
* Fever (usually high)
* Cough
* Sore throat
* Runny or stuffy nose
* Headache
* Muscle or body aches
* Fatigue (tiredness)
* Diarrhea and nausea (more common in children than adults)
Influenza can lead to serious complications, such as pneumonia, bronchitis, and sinus and ear infections. These complications are more likely to occur in people who have a weakened immune system, such as the elderly, young children, and people with certain chronic health conditions (like heart disease, diabetes, and lung disease).
Influenza is diagnosed based on a physical examination and medical history. A healthcare provider may also use a rapid influenza test (RIT) or a polymerase chain reaction (PCR) test to confirm the diagnosis.
Treatment for influenza typically involves rest, hydration, and over-the-counter medications such as acetaminophen (Tylenol) or ibuprofen (Advil, Motrin) to relieve fever and body aches. Antiviral medications, such as oseltamivir (Tamiflu) or zanamivir (Relenza), may also be prescribed to help shorten the duration and severity of the illness. However, these medications are most effective when started within 48 hours of the onset of symptoms.
Prevention is key in avoiding influenza. Vaccination is the most effective way to prevent influenza, as well as practicing good hygiene such as washing your hands frequently, avoiding close contact with people who are sick, and staying home when you are sick.
Source: 'Rubella' in Duane Gubler (ed.), up-to-date online clinical reference, retrieved on March 14, 2023 from
Examples of autoimmune diseases include:
1. Rheumatoid arthritis (RA): A condition where the immune system attacks the joints, leading to inflammation, pain, and joint damage.
2. Lupus: A condition where the immune system attacks various body parts, including the skin, joints, and organs.
3. Hashimoto's thyroiditis: A condition where the immune system attacks the thyroid gland, leading to hypothyroidism.
4. Multiple sclerosis (MS): A condition where the immune system attacks the protective covering of nerve fibers in the central nervous system, leading to communication problems between the brain and the rest of the body.
5. Type 1 diabetes: A condition where the immune system attacks the insulin-producing cells in the pancreas, leading to high blood sugar levels.
6. Guillain-Barré syndrome: A condition where the immune system attacks the nerves, leading to muscle weakness and paralysis.
7. Psoriasis: A condition where the immune system attacks the skin, leading to red, scaly patches.
8. Crohn's disease and ulcerative colitis: Conditions where the immune system attacks the digestive tract, leading to inflammation and damage to the gut.
9. Sjögren's syndrome: A condition where the immune system attacks the glands that produce tears and saliva, leading to dry eyes and mouth.
10. Vasculitis: A condition where the immune system attacks the blood vessels, leading to inflammation and damage to the blood vessels.
The symptoms of autoimmune diseases vary depending on the specific disease and the organs or tissues affected. Common symptoms include fatigue, fever, joint pain, skin rashes, and swollen lymph nodes. Treatment for autoimmune diseases typically involves medication to suppress the immune system and reduce inflammation, as well as lifestyle changes such as dietary changes and stress management techniques.
Mumps is typically diagnosed based on a combination of symptoms and physical examination findings. Laboratory tests such as PCR or IgG antibody testing may also be performed to confirm the diagnosis. There is no specific treatment for mumps, but supportive care such as pain management and hydration may be provided to alleviate symptoms. Vaccines are available to prevent mumps, and they are most effective when given before exposure to the virus.
The medical field has a clear definition of mumps, which is essential for accurate diagnosis, treatment, and prevention of the disease. The World Health Organization (WHO) defines mumps as "a contagious viral infection that affects the salivary glands, particularly the parotid gland." The Centers for Disease Control and Prevention (CDC) also provides guidelines for diagnosis, treatment, and prevention of mumps.
In conclusion, mumps is a viral infection that affects the salivary glands and can cause pain, discomfort, and potentially serious complications. The medical field has a clear definition of mumps, which is essential for accurate diagnosis, treatment, and prevention of the disease. Vaccines are available to prevent mumps, and they are most effective when given before exposure to the virus.
Types of Pneumococcal Infections:
1. Pneumonia: This is an infection of the lungs that can cause fever, cough, chest pain, and difficulty breathing.
2. Meningitis: This is an infection of the membranes that cover the brain and spinal cord, which can cause fever, headache, stiff neck, and confusion.
3. Septicemia (bloodstream infection): This is an infection of the blood that can cause fever, chills, and low blood pressure.
4. Sinusitis: This is an infection of the sinuses, which can cause headache, facial pain, and difficulty breathing through the nose.
5. Otitis media (middle ear infection): This is an infection of the middle ear, which can cause ear pain, fever, and hearing loss.
Causes and Risk Factors:
Pneumococcal infections are caused by the bacteria Streptococcus pneumoniae. These bacteria can be spread through close contact with an infected person, such as touching or sharing food and drinks. People who are at high risk for developing pneumococcal infections include:
1. Children under the age of 5 and adults over the age of 65.
2. People with weakened immune systems, such as those with cancer, HIV/AIDS, or taking medications that suppress the immune system.
3. Smokers and people with chronic respiratory diseases, such as asthma or chronic obstructive pulmonary disease (COPD).
4. People who have recently had surgery or have a severe injury.
5. Those who live in long-term care facilities or have limited access to healthcare.
Prevention and Treatment:
Preventing pneumococcal infections is important, especially for high-risk individuals. Here are some ways to prevent and treat pneumococcal infections:
1. Vaccination: The pneumococcal conjugate vaccine (PCV) is recommended for children under the age of 5 and adults over the age of 65, as well as for people with certain medical conditions.
2. Hand washing: Frequent hand washing can help prevent the spread of pneumococcal bacteria.
3. Good hygiene: Avoiding close contact with people who are sick and regularly cleaning surfaces that may be contaminated with bacteria can also help prevent infection.
4. Antibiotics: Pneumococcal infections can be treated with antibiotics, but overuse of antibiotics can lead to the development of antibiotic-resistant bacteria. Therefore, antibiotics should only be used when necessary and under the guidance of a healthcare professional.
5. Supportive care: Those with severe pneumococcal infections may require hospitalization and supportive care, such as oxygen therapy or mechanical ventilation.
Conclusion:
Pneumococcal infections can be serious and even life-threatening, especially for high-risk individuals. Prevention and prompt treatment are key to reducing the risk of complications and improving outcomes. Vaccination, good hygiene practices, and appropriate antibiotic use are all important in preventing and treating pneumococcal infections. If you suspect that you or a loved one has a pneumococcal infection, it is essential to seek medical attention right away. With proper care and support, many people with pneumococcal infections can recover fully and resume their normal lives.
The symptoms of hepatitis B can range from mild to severe and may include fatigue, loss of appetite, nausea, vomiting, abdominal pain, dark urine, pale stools, joint pain, and jaundice (yellowing of the skin and eyes). In some cases, hepatitis B can be asymptomatic, meaning that individuals may not experience any symptoms at all.
Hepatitis B is diagnosed through blood tests that detect the presence of HBV antigens or antibodies in the body. Treatment for acute hepatitis B typically involves rest, hydration, and medication to manage symptoms, while chronic hepatitis B may require ongoing therapy with antiviral drugs to suppress the virus and prevent liver damage.
Preventive measures for hepatitis B include vaccination, which is recommended for individuals at high risk of infection, such as healthcare workers, sexually active individuals, and those traveling to areas where HBV is common. In addition, safe sex practices, avoiding sharing of needles or other bodily fluids, and proper sterilization of medical equipment can help reduce the risk of transmission.
Overall, hepatitis B is a serious infection that can have long-term consequences for liver health, and it is important to take preventive measures and seek medical attention if symptoms persist or worsen over time.
Orthomyxoviridae infections are a group of viral infections caused by the Orthomyxoviridae family of viruses, which includes influenza A and B viruses, as well as other related viruses. These infections can affect both humans and animals and can cause a range of symptoms, from mild to severe.
The most common type of Orthomyxoviridae infection is seasonal influenza, which occurs when the virus is transmitted from person to person through the air or by contact with infected surfaces. Other types of Orthomyxoviridae infections include:
1. Pandemic influenza: This occurs when a new strain of the virus emerges and spreads quickly around the world, causing widespread illness and death. Examples of pandemic influenza include the Spanish flu of 1918 and the Asian flu of 1957.
2. Avian influenza: This occurs when birds are infected with the virus and can be transmitted to humans through close contact with infected birds or their droppings.
3. Swine influenza: This occurs when pigs are infected with the virus and can be transmitted to humans through close contact with infected pigs or their droppings.
4. H5N1 and H7N9: These are two specific types of bird flu viruses that have caused serious outbreaks in humans in recent years.
Symptoms of Orthomyxoviridae infections can include fever, cough, sore throat, runny nose, muscle aches, and fatigue. In severe cases, these infections can lead to pneumonia, bronchitis, and other respiratory complications, as well as hospitalization and even death.
Diagnosis of Orthomyxoviridae infections is typically made through a combination of physical examination, medical history, and laboratory tests, such as PCR (polymerase chain reaction) or viral culture. Treatment is generally focused on relieving symptoms and supporting the immune system, with antiviral medications may be used in severe cases.
Prevention of Orthomyxoviridae infections can include avoiding close contact with infected birds or pigs, wearing protective clothing and gear when handling animals, and practicing good hygiene such as washing hands frequently. Vaccines are also available for some species of birds and pigs to protect against these viruses.
Overall, Orthomyxoviridae is a family of viruses that can cause serious illness in humans and other animals, and it's important to take precautions to prevent exposure and spread of these viruses.
Epidemiology of Haemophilus Infections:
* Incidence: Hib disease was once a major cause of childhood meningitis and sepsis, but the introduction of Hib vaccines in the 1980s has significantly reduced the incidence of invasive Hib disease. Non-invasive Hib disease, such as otitis media, is still common.
* Prevalence: Hib is the leading cause of bacterial meningitis in children under the age of 5 worldwide. In developed countries, the prevalence of invasive Hib disease has decreased significantly since the introduction of vaccines, but it remains a significant public health problem in developing countries.
* Risk factors: young age, poverty, lack of access to healthcare, and poor sanitation and hygiene are risk factors for Hib disease. Children under the age of 5, especially those under the age of 2, are at highest risk for invasive Hib disease.
Pathophysiology of Haemophilus Infections:
* Mechanisms of infection: H. influenzae can cause both respiratory and non-respiratory infections by colonizing the nasopharynx and other mucosal surfaces. The bacteria can then disseminate to other parts of the body, causing invasive disease.
* Immune response: the immune response to Hib infection involves both humoral and cell-mediated immunity. Antibodies play a crucial role in protecting against reinfection, while T cells and macrophages help to clear the bacteria from the body.
Clinical Presentation of Haemophilus Infections:
* Respiratory infections: H. influenzae can cause various respiratory tract infections, including bronchitis, pneumonia, and sinusitis. Symptoms may include fever, cough, sore throat, and difficulty breathing.
* Non-respiratory infections: Hib can cause a range of non-respiratory infections, including meningitis, epiglottitis, and septic arthritis. These infections can have more severe symptoms and may require prompt medical attention.
Diagnosis of Haemophilus Infections:
* Diagnostic tests: diagnosis of Hib disease is based on a combination of clinical findings, laboratory tests, and radiologic studies. Blood cultures, lumbar puncture, and chest x-rays may be used to confirm the presence of the bacteria and assess the extent of infection.
* Laboratory testing: identification of Hib is based on its distinctive gram stain appearance and biochemical characteristics. Polymerase chain reaction (PCR) and DNA sequencing are also used to confirm the diagnosis.
Treatment and Prevention of Haemophilus Infections:
* Antibiotics: Hib infections are treated with antibiotics, such as amoxicillin or ceftriaxone. The choice of antibiotic depends on the severity and location of the infection.
* Vaccination: the Hib vaccine is recommended for children under 5 years old to prevent Hib disease. The vaccine is given in a series of 3-4 doses, with the first dose given at 2 months of age.
* Good hygiene practices: good hygiene practices, such as frequent handwashing and proper cleaning and disinfection, can help prevent the spread of Hib bacteria.
Complications of Haemophilus Infections:
* Meningitis: Hib meningitis can have serious complications, including hearing loss, learning disabilities, and seizures.
* Permanent brain damage: Hib infections can cause permanent brain damage, including cognitive and behavioral impairments.
* Respiratory failure: severe Hib pneumonia can lead to respiratory failure, which may require mechanical ventilation.
* Death: Hib infections can be life-threatening, especially in young children and those with underlying medical conditions.
In conclusion, Haemophilus infections are a serious public health concern, particularly for young children and those with underlying medical conditions. Prevention through vaccination and good hygiene practices is essential to reduce the risk of infection. Early diagnosis and treatment are critical to prevent complications and improve outcomes.
There are several different types of malaria, including:
1. Plasmodium falciparum: This is the most severe form of malaria, and it can be fatal if left untreated. It is found in many parts of the world, including Africa, Asia, and Latin America.
2. Plasmodium vivax: This type of malaria is less severe than P. falciparum, but it can still cause serious complications if left untreated. It is found in many parts of the world, including Africa, Asia, and Latin America.
3. Plasmodium ovale: This type of malaria is similar to P. vivax, but it can cause more severe symptoms in some people. It is found primarily in West Africa.
4. Plasmodium malariae: This type of malaria is less common than the other three types, and it tends to cause milder symptoms. It is found primarily in parts of Africa and Asia.
The symptoms of malaria can vary depending on the type of parasite that is causing the infection, but they typically include:
1. Fever
2. Chills
3. Headache
4. Muscle and joint pain
5. Fatigue
6. Nausea and vomiting
7. Diarrhea
8. Anemia (low red blood cell count)
If malaria is not treated promptly, it can lead to more severe complications, such as:
1. Seizures
2. Coma
3. Respiratory failure
4. Kidney failure
5. Liver failure
6. Anemia (low red blood cell count)
Malaria is typically diagnosed through a combination of physical examination, medical history, and laboratory tests, such as blood smears or polymerase chain reaction (PCR) tests. Treatment for malaria typically involves the use of antimalarial drugs, such as chloroquine or artemisinin-based combination therapies. In severe cases, hospitalization may be necessary to manage complications and provide supportive care.
Prevention is an important aspect of managing malaria, and this can include:
1. Using insecticide-treated bed nets
2. Wearing protective clothing and applying insect repellent when outdoors
3. Eliminating standing water around homes and communities to reduce the number of mosquito breeding sites
4. Using indoor residual spraying (IRS) or insecticide-treated wall lining to kill mosquitoes
5. Implementing malaria control measures in areas where malaria is common, such as distribution of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS)
6. Improving access to healthcare services, particularly in rural and remote areas
7. Providing education and awareness about malaria prevention and control
8. Encouraging the use of preventive medications, such as intermittent preventive treatment (IPT) for pregnant women and children under the age of five.
Early diagnosis and prompt treatment are critical in preventing the progression of malaria and reducing the risk of complications and death. In areas where malaria is common, it is essential to have access to reliable diagnostic tools and effective antimalarial drugs.
The disease is typically induced in laboratory animals such as mice or rats by immunizing them with myelin proteins, such as myelin basic protein (MBP) or proteolipid protein (PLP), emulsified in adjuvants. The resulting immune response leads to the production of autoantibodies and activated T cells that cross the blood-brain barrier and attack the CNS.
EAE is used as a model for MS because it shares many similarities with the human disease, including:
1. Demyelination: EAE induces demyelination of nerve fibers in the CNS, which is also a hallmark of MS.
2. Autoimmune response: The immune response in EAE is triggered by autoantigens, similar to MS.
3. Chronic course: EAE is a chronic disease with recurrent relapses, similar to MS.
4. Lesion distribution: EAE lesions are distributed throughout the CNS, including the cerebral cortex, cerebellum, brainstem, and spinal cord, which is also true for MS.
EAE has been used extensively in the study of MS to investigate the immunopathogenesis of the disease, to develop new diagnostic markers and treatments, and to test the efficacy of potential therapeutic agents.
The symptoms of rabies can vary depending on the severity of the infection and the individual's overall health. Early symptoms may include fever, headache, weakness, and fatigue. As the disease progresses, symptoms can become more severe and can include:
* Agitation and confusion
* Seizures and paralysis
* Hydrophobia (fear of water)
* Spasms and twitching
* Increased salivation
* Fever and chills
* Weakness and paralysis of the face, arms, and legs
If left untreated, rabies is almost always fatal. However, prompt medical attention, including the administration of post-exposure prophylaxis (PEP), can prevent the disease from progressing and save the life of an infected person. PEP typically involves a series of injections with rabies immune globulin and a rabies vaccine.
Rabies is a significant public health concern, particularly in developing countries where access to medical care may be limited. According to the World Health Organization (WHO), there are an estimated 55,000-60,000 human deaths from rabies each year, mostly in Asia and Africa. In the United States, rabies is relatively rare, with only a few cases reported each year. However, it is still important for individuals to be aware of the risks of rabies and take precautions to prevent exposure, such as avoiding contact with wild animals and ensuring that pets are up-to-date on their vaccinations.
1. Bubonic plague: This is the most common form of the disease and is characterized by the development of swollen and painful lymph nodes (called buboes) in the groin, armpits, or neck.
2. Pneumonic plague: This form of the disease affects the lungs and can be transmitted from person to person through respiratory droplets. It is highly contagious and can be fatal if left untreated.
3. Septicemic plague: This form of the disease occurs when the bacteria enter the bloodstream directly, without going through the lymph nodes or lungs. It can cause fever, chills, abdominal pain, and bleeding into the skin and organs.
Plague has a long history of being a major public health threat, with pandemics occurring in the Middle Ages and other times throughout history. In modern times, plague is still present in some parts of the world, particularly in rural areas of the western United States and in parts of Africa and Asia.
Treatment of plague typically involves antibiotics, which can be effective if started early in the course of the illness. However, resistance to these antibiotics has been a growing concern in recent years, making it increasingly difficult to treat the disease effectively.
Prevention of plague primarily involves controlling the population of infected fleas and other vectors, as well as avoiding contact with infected animals or people. This can be achieved through measures such as using insecticides, wearing protective clothing and gear, and practicing good hygiene. Vaccines are also available for some forms of the disease, but they are not widely used due to their limited effectiveness and the availability of other treatment options.
Overall, plague is a serious and potentially deadly disease that requires prompt medical attention if symptoms persist or worsen over time. While treatment options exist, prevention is key to avoiding infection and controlling the spread of the disease.
The symptoms of rotavirus infection can range from mild to severe and may include:
* Diarrhea
* Vomiting
* Fever
* Abdominal pain
* Dehydration
* Loss of appetite
* Weight loss
In severe cases, rotavirus infection can lead to complications such as:
* Dehydration
* Malnutrition
* Electrolyte imbalance
* Acute kidney injury
* Septicemia
* Death (rare)
The diagnosis of rotavirus infection is based on a combination of clinical symptoms, laboratory tests, and medical imaging. Laboratory tests may include:
* Stool testing for the presence of rotavirus antigens or genetic material
* Blood testing for signs of dehydration or electrolyte imbalance
There is no specific treatment for rotavirus infection, but rather supportive care to manage symptoms and prevent complications. This may include:
* Fluid replacement therapy to prevent dehydration
* Anti-diarrheal medications to slow down bowel movements
* Pain management with medication
* Rest and hydration
Prevention is key in managing rotavirus infections. Vaccines are available to protect against rotavirus infection, and good hygiene practices such as frequent handwashing and avoiding close contact with people who are sick can also help prevent the spread of the virus.
Overall, while rotavirus infections can be severe and potentially life-threatening, with proper supportive care and prevention measures, most children recover fully within a few days to a week.
Once infected, a person will usually develop symptoms within 2-3 weeks after exposure. The symptoms can be mild or severe, and may include:
* Fever (usually low grade)
* Headache
* Sore throat
* Muscle aches
* Fatigue
* Loss of appetite
* Itchy skin rash
The rash typically appears as small, fluid-filled blisters that are highly contagious and can spread to others through direct contact with the rash. The rash may appear on any part of the body, including the face, scalp, arms, legs, and torso. As the rash progresses, it may become crusted over and form scabs.
In some cases, complications can arise from chickenpox, such as:
* Bacterial infections (e.g. strep throat)
* Pneumonia
* Encephalitis (inflammation of the brain)
* Meningitis (inflammation of the membranes surrounding the brain and spinal cord)
* Blood infections (sepsis)
* Shingles (a painful rash that occurs in adults who have had chickenpox before)
There is no specific treatment for chickenpox, but antiviral medications can help reduce the severity and duration of symptoms. Over-the-counter medications such as acetaminophen (Tylenol) or ibuprofen (Advil) can be used to relieve fever and pain. Home remedies such as cool baths, calamine lotion, and chickenpox creams may also provide relief from itching and discomfort.
Prevention is key in avoiding chickenpox, and the best way to do this is through vaccination. The varicella vaccine is recommended for children ages 12-15 months, with a second dose given before entering kindergarten (around age 4-6 years). The vaccine is also recommended for individuals who have not had chickenpox and are over the age of 13. Adults who have not had chickenpox or been vaccinated can take steps to avoid exposure, such as avoiding contact with infected individuals and practicing good hygiene (e.g. washing hands frequently).
In conclusion, chickenpox is a highly contagious illness that can cause discomfort and complications. Prevention through vaccination is the best way to avoid getting sick, and antiviral medications and home remedies can help reduce symptoms if infected. If you suspect you or your child has chickenpox, it's important to contact a healthcare professional for proper diagnosis and treatment.
Hepatitis A is typically spread through contaminated food and water or through close contact with someone who has the infection. The virus can also be spread through sexual contact or sharing of needles.
Symptoms of hepatitis A usually appear two to six weeks after exposure and can last for several weeks or months. In some cases, the infection can lead to complications such as liver failure, which can be life-threatening.
There is a vaccine available for hepatitis A, which is recommended for individuals traveling to areas where the virus is common, people who engage in high-risk behaviors, and those with chronic liver disease. Treatment for hepatitis A typically focuses on relieving symptoms and supporting the liver as it recovers. In severe cases, hospitalization may be necessary.
Preventive measures to reduce the risk of hepatitis A infection include maintaining good hygiene practices, such as washing hands frequently, especially before eating or preparing food; avoiding consumption of raw or undercooked shellfish, particularly oysters; and avoiding close contact with people who have the infection.
Synonyms: JE
Definition:
A viral infection that affects the brain and is transmitted by the bite of an infected Culex species mosquito. The virus is found throughout Asia and the western Pacific region.
Symptoms:
* Fever
* Headache
* Vomiting
* Seizures
* Confusion
* Weakness in the limbs
Diagnosis:
* Blood tests to detect antibodies against the virus
* Imaging studies such as CT or MRI scans to look for signs of brain inflammation
Treatment:
* Supportive care, such as intravenous fluids and oxygen therapy, to manage symptoms and prevent complications
* Antiviral medications may be given in some cases
Prognosis:
* The prognosis for Japanese encephalitis is generally good if treatment is received promptly and the patient is otherwise healthy. However, in severe cases or those with underlying medical conditions, the virus can cause significant brain damage and lead to long-term complications or death.
Prevention:
* Vaccination against Japanese encephalitis is recommended for people who live in or travel to areas where the virus is common, particularly children and adults who plan to spend extended periods of time outdoors. The vaccine is effective in preventing severe illness and death from the virus.
* Mosquito control measures, such as using insect repellents and wearing protective clothing, can also help reduce the risk of infection.
The most common form of this disease is Meningococcal Group B (MenB). Symptoms often develop within hours or days after exposure, but can be nonspecific, such as fever, headache, and muscle aches.
Early signs that are more specific and suggestive of the diagnosis include neck stiffness, confusion, seizures, and rash. Diagnosis is by culture or PCR of a sterile site. Treatment consists of antibiotics that cover Neisseria meningitidis, which should be initiated promptly after recognition of the signs and symptoms.
Prevention with vaccines is recommended for infants at 2 months of age; boosters are given at 4 months, 6 months, and 12 to 15 months of age.
There are several different types of uveitis, including:
1. Anterior uveitis: This type affects the front part of the eye and is the most common form of uveitis. It is often caused by an infection or injury.
2. Posterior uveitis: This type affects the back part of the eye and can be caused by a systemic disease such as sarcoidosis or juvenile idiopathic arthritis.
3. Intermediate uveitis: This type affects the middle layer of the eye and is often caused by an autoimmune disorder.
4. Panuveitis: This type affects the entire uvea and can be caused by a systemic disease such as vasculitis or Behçet's disease.
Symptoms of uveitis may include:
* Eye pain
* Redness and swelling in the eye
* Blurred vision
* Sensitivity to light
* Floaters (specks or cobwebs in your vision)
* Flashes of light
If you experience any of these symptoms, it is important to see an eye doctor as soon as possible. Uveitis can be diagnosed with a comprehensive eye exam, which may include imaging tests such as ultrasound or MRI. Treatment for uveitis depends on the cause and severity of the condition, but may include medication to reduce inflammation, antibiotics for infections, or surgery to remove any diseased tissue.
Early diagnosis and treatment are important to prevent complications such as cataracts, glaucoma, and blindness. If you have uveitis, it is important to follow your doctor's recommendations for treatment and monitoring to protect your vision.
Smallpox symptoms include fever, headache, and fatigue, followed by a characteristic rash that spreads from the face to other parts of the body. The disease is highly infectious and can be fatal, especially among young children and immunocompromised individuals. There is no specific treatment for smallpox, and vaccination is the most effective method of prevention.
The last naturally occurring case of smallpox was reported in 1977, and since then, there have been only a few laboratory-confirmed cases, all related to research on the virus. The WHO declared that smallpox had been eradicated in 1980, making it the first and only human disease to be completely eliminated from the planet.
While the risk of smallpox is currently low, there is concern that the virus could be used as a bioterrorism agent, and efforts are being made to maintain surveillance and preparedness for any potential outbreaks.
Yellow fever is a serious and sometimes fatal disease, with a high mortality rate in unvaccinated individuals. However, it can be prevented through vaccination, which is recommended for all travelers to areas where the virus is present. The Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO) both recommend that travelers to these areas receive a yellow fever vaccine at least 10 days before travel to ensure adequate protection.
Yellow fever is not contagious, meaning it cannot be spread from person to person through casual contact. However, infected mosquitoes can transmit the virus to other animals and humans. The virus is most commonly found in monkeys and other primates, which can become carriers of the disease without showing any symptoms.
There are several strains of the yellow fever virus, with some being more virulent than others. The most common strain is the Asibi strain, which is found in West Africa and is responsible for most outbreaks of the disease. Other strains include the Central African, East African, and South American strains.
Yellow fever was first identified in the 17th century in West Africa, where it was known as "yellow jack" due to the yellowish tint of the skin of infected individuals. The disease spread throughout the Americas during the colonial period, where it caused devastating outbreaks and killed millions of people. In the United States, yellow fever was eradicated in the early 20th century through vaccination and mosquito control measures. However, it still remains a significant public health threat in many parts of the world today.
Prevention of yellow fever is primarily achieved through vaccination, which is recommended for travelers to areas where the disease is common. Vaccines are available in different forms, including injectable and oral versions, and they provide long-lasting protection against the virus. In addition to vaccination, other measures can be taken to prevent the spread of yellow fever, such as using insect repellents and wearing protective clothing to prevent mosquito bites.
There is no specific treatment for yellow fever, and treatment is primarily focused on managing symptoms and supporting the body's immune response. In severe cases, hospitalization may be necessary to provide intravenous fluids and other supportive care. Antiviral medications may also be used in some cases to help reduce the severity of the disease.
Prevention is key to avoiding yellow fever, and vaccination is the most effective way to protect against this deadly disease. By understanding the causes, symptoms, and prevention methods for yellow fever, individuals can take steps to protect themselves and their loved ones from this potentially deadly illness.
These animal models allow researchers to study the underlying causes of arthritis, test new treatments and therapies, and evaluate their effectiveness in a controlled environment before moving to human clinical trials. Experimental arthritis models are used to investigate various aspects of the disease, including its pathophysiology, immunogenicity, and potential therapeutic targets.
Some common experimental arthritis models include:
1. Collagen-induced arthritis (CIA): This model is induced in mice by immunizing them with type II collagen, which leads to an autoimmune response and inflammation in the joints.
2. Rheumatoid arthritis (RA) models: These models are developed by transferring cells from RA patients into immunodeficient mice, which then develop arthritis-like symptoms.
3. Osteoarthritis (OA) models: These models are induced in animals by subjecting them to joint injury or overuse, which leads to degenerative changes in the joints and bone.
4. Psoriatic arthritis (PsA) models: These models are developed by inducing psoriasis in mice, which then develop arthritis-like symptoms.
Experimental arthritis models have contributed significantly to our understanding of the disease and have helped to identify potential therapeutic targets for the treatment of arthritis. However, it is important to note that these models are not perfect representations of human arthritis and should be used as tools to complement, rather than replace, human clinical trials.
There are several types of retinitis, including:
1. Retinitis pigmentosa: This is a group of inherited conditions that cause progressive vision loss due to degeneration of the retina.
2. Cytomegalovirus (CMV) retinitis: This is a type of retinitis caused by the CMV virus, which is common in people with weakened immune systems, such as those with HIV/AIDS.
3. Toxoplasma retinitis: This is a type of retinitis caused by the Toxoplasma gondii parasite, which can cause vision loss if left untreated.
4. Syphilitic retinitis: This is a type of retinitis caused by the bacteria Treponema pallidum, which can cause vision loss if left untreated.
5. Uveitis-related retinitis: This is a type of retinitis that occurs as a complication of uveitis, an inflammation of the uvea, the middle layer of the eye.
Symptoms of retinitis can include vision loss, blurred vision, sensitivity to light, and floaters (specks or cobwebs in your vision). If you experience any of these symptoms, it is important to seek medical attention as soon as possible.
Retinitis is typically diagnosed through a combination of physical examination, imaging tests such as optical coherence tomography (OCT), and laboratory tests to identify the underlying cause. Treatment for retinitis depends on the underlying cause and may include antiviral or antibacterial medications, immunosuppressive drugs, or surgery. In some cases, vision loss may be permanent, but early diagnosis and treatment can help prevent further damage and improve outcomes.
There are three main forms of anthrax:
1. Cutaneous (skin) anthrax: This is the most common form of the disease and causes skin lesions that can progress to severe inflammation and scarring.
2. Inhalational (lung) anthrax: This is the most deadly form of the disease and causes serious respiratory problems, including fever, chills, and difficulty breathing.
3. Gastrointestinal (GI) anthrax: This form of the disease causes symptoms such as diarrhea, abdominal pain, and vomiting.
Anthrax can be diagnosed through a variety of tests, including blood tests and imaging studies. Treatment typically involves antibiotics, but the effectiveness of treatment depends on the severity of the infection and the timing of treatment.
Prevention of anthrax primarily involves vaccination of animals and control of animal products to prevent the spread of the bacteria. In addition, public health measures such as surveillance and quarantine can help prevent the spread of the disease to humans.
The medical management of anthrax involves a combination of antibiotics, supportive care, and wound management. Early diagnosis and treatment are critical to preventing serious complications and death.
2. Our research focuses on identifying the genetic mutations that contribute to experimental melanoma and developing targeted therapies.
3. The patient's experimental melanoma had spread to her lungs and liver, so we recommended chemotherapy and immunotherapy treatments.
Vaccinia is most commonly associated with smallpox, which is caused by a similar virus and was eradicated in the late 1970s through widespread vaccination. However, there have been occasional outbreaks of vaccinia in the United States and other countries since then, often linked to laboratory accidents or deliberate releases of the virus.
The treatment of vaccinia typically involves supportive care, such as rest, hydration, and antipyretic medications to reduce fever. Antiviral medications may also be used in some cases. Prevention of the disease relies on avoiding contact with infected animals or people, and on following proper infection control practices in laboratory and healthcare settings.
Vaccinia is a serious viral infection that can have severe consequences if left untreated. It is important to seek medical attention immediately if symptoms persist or worsen over time.
The symptoms of cholera include:
1. Diarrhea: Cholera causes profuse, watery diarrhea that can last for several days.
2. Dehydration: The loss of fluids and electrolytes due to diarrhea can lead to severe dehydration, which can be life-threatening if not treated promptly.
3. Nausea and vomiting: Cholera patients may experience nausea and vomiting, especially in the early stages of the disease.
4. Abdominal cramps: The abdomen may become tender and painful due to the inflammation caused by the bacteria.
5. Low-grade fever: Some patients with cholera may experience a mild fever, typically less than 102°F (39°C).
Cholera is spread through the fecal-oral route, which means that it is transmitted when someone ingests food or water contaminated with the bacteria. The disease can also be spread by direct contact with infected fecal matter, such as through poor hygiene practices or inadequate waste disposal.
There are several ways to diagnose cholera, including:
1. Stool test: A stool sample can be tested for the presence of Vibrio cholerae using a microscope or a rapid diagnostic test (RDT).
2. Blood test: A blood test can detect the presence of antibodies against Vibrio cholerae, which can indicate that the patient has been infected with the bacteria.
3. Physical examination: A healthcare provider may perform a physical examination to look for signs of dehydration and other symptoms of cholera.
Treatment of cholera typically involves replacing lost fluids and electrolytes through oral rehydration therapy (ORT) or intravenous fluids. Antibiotics may also be given to shorten the duration of diarrhea and reduce the risk of complications. In severe cases, hospitalization may be necessary to provide more intensive treatment.
Prevention of cholera involves maintaining good hygiene practices, such as washing hands with soap and water, and avoiding consumption of contaminated food and water. Vaccines are also available to protect against cholera, particularly for people living in areas where the disease is common.
In conclusion, cholera is a highly infectious disease that can cause severe dehydration and even death if left untreated. Early diagnosis and treatment are critical to preventing complications and reducing the risk of transmission. Prevention measures such as vaccination and good hygiene practices can also help control the spread of the disease.
Types of experimental neoplasms include:
* Xenografts: tumors that are transplanted into animals from another species, often humans.
* Transgenic tumors: tumors that are created by introducing cancer-causing genes into an animal's genome.
* Chemically-induced tumors: tumors that are caused by exposure to certain chemicals or drugs.
The use of experimental neoplasms in research has led to significant advances in our understanding of cancer biology and the development of new treatments for the disease. However, the use of animals in cancer research is a controversial topic and alternatives to animal models are being developed and implemented.
SAIDS was first identified in the 1980s in monkeys that were being used in research laboratories, and it has since been studied extensively as a model for HIV/AIDS research. Like HIV/AIDS, SAIDS is caused by the transmission of a virus from one animal to another through contact with infected bodily fluids, such as blood or semen.
The symptoms of SAIDS are similar to those of HIV/AIDS and include fever, fatigue, weight loss, and opportunistic infections. As the disease progresses, animals may also experience neurological symptoms, such as seizures and difficulty coordinating movements.
There is currently no cure for SAIDS, and treatment is focused on managing the symptoms and preventing complications. Research into the disease has led to a greater understanding of the immunopathogenesis of HIV/AIDS and has contributed to the development of new therapies for the disease.
SAIDS is important in medical research because it provides a valuable model for studying the immunopathogenesis of HIV/AIDS and for testing new therapies and vaccines. It also serves as a reminder of the importance of strict safety protocols when working with infectious agents, particularly in laboratory settings.
Symptoms of meningococcal meningitis typically develop within 3-7 days after exposure and may include fever, headache, stiff neck, confusion, nausea and vomiting, sensitivity to light, and seizures. In severe cases, the infection can lead to shock, organ failure, and death within hours of the onset of symptoms.
Diagnosis is typically made by a combination of physical examination, laboratory tests (such as blood cultures and PCR), and imaging studies (such as CT or MRI scans). Treatment typically involves antibiotics, intravenous fluids, and supportive care to manage fever, pain, and other symptoms. In severe cases, hospitalization in an intensive care unit may be necessary.
Prevention of meningococcal meningitis includes the use of vaccines, good hygiene practices (such as frequent handwashing), and avoidance of close contact with people who are sick. A vaccine is available for children and teens, and some colleges and universities require students to be vaccinated before moving into dorms.
Early diagnosis and treatment are crucial in preventing long-term complications and reducing the risk of death from meningococcal meningitis. If you suspect that you or someone else may have meningococcal meningitis, it is important to seek medical attention immediately.
Osteoarthritis (OA) is a degenerative condition that occurs when the cartilage that cushions the joints breaks down over time, causing the bones to rub together. It is the most common form of arthritis and typically affects older adults.
Rheumatoid arthritis (RA) is an autoimmune condition that occurs when the body's immune system attacks the lining of the joints, leading to inflammation and pain. It can affect anyone, regardless of age, and is typically seen in women.
Other types of arthritis include psoriatic arthritis, gouty arthritis, and lupus-related arthritis. Treatment for arthritis depends on the type and severity of the condition, but can include medications such as pain relievers, anti-inflammatory drugs, and disease-modifying anti-rheumatic drugs (DMARDs). Physical therapy and lifestyle changes, such as exercise and weight loss, can also be helpful. In severe cases, surgery may be necessary to repair or replace damaged joints.
Arthritis is a leading cause of disability worldwide, affecting over 50 million adults in the United States alone. It can have a significant impact on a person's quality of life, making everyday activities such as walking, dressing, and grooming difficult and painful. Early diagnosis and treatment are important to help manage symptoms and slow the progression of the disease.
The symptoms of CRS can vary widely depending on the severity of the infection and the stage of pregnancy at which it occurs. Some common birth defects associated with CRS include:
1. Heart defects: CRS can cause defects such as patent ductus arteriosus, atrial septal defect, and ventricular septal defect.
2. Neurological defects: CRS can lead to a range of neurological problems including microcephaly (small head size), mental retardation, and seizures.
3. Eye defects: CRS can cause eye problems such as cataracts, glaucoma, and blindness.
4. Ear defects: CRS can lead to ear problems such as hearing loss and deafness.
5. Thyroid disorders: CRS can cause thyroid problems including cretinism, a condition characterized by mental retardation and physical deformities.
6. Bone and joint defects: CRS can cause bone and joint problems such as arthrogryposis (a condition characterized by joint contractures) and clubfoot.
7. Skin defects: CRS can lead to skin problems such as macular rash, which is a red, itchy rash that appears on the skin.
8. Other defects: CRS can also cause other birth defects such as deafness, mutism, and cognitive impairment.
CRS is diagnosed based on a combination of clinical findings, laboratory tests, and imaging studies. There is no specific treatment for CRS, but management of the condition involves supportive care to prevent complications and manage symptoms. Prevention of CRS relies on vaccination of pregnant women against rubella, which has led to a significant decline in the incidence of the condition.
The prognosis for children with CRS varies depending on the severity of the infection and the presence of any underlying medical conditions. Some children may have mild symptoms and recover fully, while others may experience more severe complications that can result in long-term disability or death. Early diagnosis and management are essential to improve outcomes for affected children.
Symptoms of orchitis may include:
* Scrotal pain
* Swelling of the scrotum
* Redness and tenderness of the scrotum
* Fever
* Chills
* Abdominal pain
* Nausea and vomiting
Treatment for orchitis typically involves antibiotics to clear up any bacterial infections, as well as supportive care such as rest, ice packs, and over-the-counter pain medication. In severe cases, hospitalization may be necessary to monitor and treat the condition.
Prevention of orchitis includes avoiding close contact with people who have the infection, practicing safe sex, and maintaining good hygiene. Vaccination against certain types of bacteria that can cause orchitis, such as the H. influenzae type b (Hib) vaccine, can also help prevent the condition.
It is important to seek medical attention if symptoms of orchitis are present, as early treatment can help prevent complications and improve outcomes.
Isoimmunization is a condition that occurs when an individual has antibodies against their own red blood cell antigens, specifically the Rh antigen. This can happen due to various reasons such as:
1. Incompatibility between the mother's and father's Rh antigens, leading to the development of antibodies in the mother during pregnancy or childbirth.
2. Blood transfusions from an incompatible donor.
3. Certain medical conditions like autoimmune hemolytic anemia or bone marrow transplantation.
Rh isoimmunization can lead to a range of complications, including:
1. Hemolytic disease of the newborn: This is a condition where the baby's red blood cells are destroyed by the mother's antibodies, leading to anemia, jaundice, and other serious complications.
2. Rh hemolytic crisis: This is a severe and potentially life-threatening complication that can occur during pregnancy or childbirth.
3. Chronic hemolytic anemia: This is a condition where the red blood cells are continuously destroyed, leading to anemia and other complications.
Rh isoimmunization can be diagnosed through blood tests such as the direct antiglobulin test (DAT) or the indirect Coombs test (ICT). Treatment typically involves managing any underlying conditions and monitoring for complications. In severe cases, a bone marrow transplant may be necessary. Prevention is key, and women who are Rh-negative should receive an injection of Rh immune globulin during pregnancy to prevent the development of antibodies against the Rh antigen.
HIV (human immunodeficiency virus) infection is a condition in which the body is infected with HIV, a type of retrovirus that attacks the body's immune system. HIV infection can lead to AIDS (acquired immunodeficiency syndrome), a condition in which the immune system is severely damaged and the body is unable to fight off infections and diseases.
There are several ways that HIV can be transmitted, including:
1. Sexual contact with an infected person
2. Sharing of needles or other drug paraphernalia with an infected person
3. Mother-to-child transmission during pregnancy, childbirth, or breastfeeding
4. Blood transfusions ( although this is rare in developed countries due to screening processes)
5. Organ transplantation (again, rare)
The symptoms of HIV infection can be mild at first and may not appear until several years after infection. These symptoms can include:
1. Fever
2. Fatigue
3. Swollen glands in the neck, armpits, and groin
4. Rash
5. Muscle aches and joint pain
6. Night sweats
7. Diarrhea
8. Weight loss
If left untreated, HIV infection can progress to AIDS, which is a life-threatening condition that can cause a wide range of symptoms, including:
1. Opportunistic infections (such as pneumocystis pneumonia)
2. Cancer (such as Kaposi's sarcoma)
3. Wasting syndrome
4. Neurological problems (such as dementia and seizures)
HIV infection is diagnosed through a combination of blood tests and physical examination. Treatment typically involves antiretroviral therapy (ART), which is a combination of medications that work together to suppress the virus and slow the progression of the disease.
Prevention methods for HIV infection include:
1. Safe sex practices, such as using condoms and dental dams
2. Avoiding sharing needles or other drug-injecting equipment
3. Avoiding mother-to-child transmission during pregnancy, childbirth, or breastfeeding
4. Post-exposure prophylaxis (PEP), which is a short-term treatment that can prevent infection after potential exposure to the virus
5. Pre-exposure prophylaxis (PrEP), which is a daily medication that can prevent infection in people who are at high risk of being exposed to the virus.
It's important to note that HIV infection is manageable with proper treatment and care, and that people living with HIV can lead long and healthy lives. However, it's important to be aware of the risks and take steps to prevent transmission.
There are several types of disease susceptibility, including:
1. Genetic predisposition: This refers to the inherent tendency of an individual to develop a particular disease due to their genetic makeup. For example, some families may have a higher risk of developing certain diseases such as cancer or heart disease due to inherited genetic mutations.
2. Environmental susceptibility: This refers to the increased risk of developing a disease due to exposure to environmental factors such as pollutants, toxins, or infectious agents. For example, someone who lives in an area with high levels of air pollution may be more susceptible to developing respiratory problems.
3. Lifestyle susceptibility: This refers to the increased risk of developing a disease due to unhealthy lifestyle choices such as smoking, lack of exercise, or poor diet. For example, someone who smokes and is overweight may be more susceptible to developing heart disease or lung cancer.
4. Immune system susceptibility: This refers to the increased risk of developing a disease due to an impaired immune system. For example, people with autoimmune disorders such as HIV/AIDS or rheumatoid arthritis may be more susceptible to opportunistic infections.
Understanding disease susceptibility can help healthcare providers identify individuals who are at risk of developing certain diseases and provide preventive measures or early intervention to reduce the risk of disease progression. Additionally, genetic testing can help identify individuals with a high risk of developing certain diseases, allowing for earlier diagnosis and treatment.
In summary, disease susceptibility refers to the predisposition of an individual to develop a particular disease or condition due to various factors such as genetics, environment, lifestyle choices, and immune system function. Understanding disease susceptibility can help healthcare providers identify individuals at risk and provide appropriate preventive measures or early intervention to reduce the risk of disease progression.
Immunization
Active immunization
Cocooning (immunization)
Immunization Alliance
Immunization (finance)
Immunization registry
Immunization during pregnancy
Immunization Action Coalition
European Immunization Week
Targeted immunization strategies
World Immunization Week
World Immunization Week 2022
Anthrax Vaccine Immunization Program
Expanded Program on Immunization
Immunization of School Pupils Act
National Immunization Technical Advisory Group
National Advisory Committee on Immunization
Expanded Program on Immunization (Philippines)
Advisory Committee on Immunization Practices
National Advisory Group on Immunization
Universal Immunisation Programme
National Center for Immunization and Respiratory Diseases
National Immunisation Program Schedule
National Immunisation Advisory Committee
Immunisation Programme in Hong Kong
Immunisation Advisory Centre, New Zealand
Childhood immunizations in the United States
Australian Technical Advisory Group on Immunisation
The Green Book (immunisation guidance, UK)
Joint Committee on Vaccination and Immunisation
FastStats - Immunization
Public Report for INNO-LIA HCV Score, (PQDx 0202-073-00) | WHO - Prequalification of Medical Products (IVDs, Medicines,...
Immunization | Medscape
7th Grade Immunization Requirement
Immunization, 1992
NHANES 2005-2006:
Immunization Data Documentation, Codebook, and Frequencies
Perspectives: Rabies Immunization | CDC Yellow Book 2024
Indiana Vaccine and Immunization Requirements
Pertussis Treatment & Management: Approach Considerations, Pharmacologic Therapy, Immunization
Personalized vaccine can provide effective immunization against cancer
Vaccines | Immunization | Inoculation | MedlinePlus
Immunization Requirements | Moorpark College
Immunization in practice: a practical guide for health staff
Role of the Advisory Committee on Immunization Practices in CDC's Vaccine Recommendations | CDC
Immunization, Prevention and Vaccine Information
Immunization Policy - Laurie Hamre Center for Health & Wellness - Macalester College
Immunization
Immunization | WHO | Regional Office for Africa
Immunization
Routine immunization profile: Iceland
Immunization Policy | The University of North Carolina at Pembroke
Thorsby Community Health Centre - Immunization - School Services | Alberta Health Services
Beaverlodge Community Health Services - Immunization - School Services | Alberta Health Services
Additional Sources of Immunization Information | Kent County, Michigan
Infectious disease and immunisation | School of Population Health - UNSW Sydney
Redirect Instant Childhood Immunization Scheduler | CDC
7.2: Immunisation | RNZCGP
Vaccines10
- The Global Vaccine Action Plan (GVAP) is a framework approved by the World Health Assembly in May 2012 to achieve the Decade of Vaccines vision by delivering universal access to immunization. (unicef.org)
- A vaccine, or immunization, schedule lists which vaccines are recommended for different groups of people. (medlineplus.gov)
- A 2009 polio immunization campaign failed to stamp out the disease because it did not reach enough children with vaccines. (voanews.com)
- Despite these achievements, national and subnational immunization coverage rates have stagnated in many countries, and the African Region still lags behind other regions of the world in access to vaccines. (who.int)
- Strategic investments to strengthen health systems are critical to support robust immunization programmes that can deliver vaccines to everyone in Africa, including the most vulnerable. (who.int)
- The Advisory Committee on Immunization Practices (ACIP) is a group of medical and public health experts that develops recommendations on how to use vaccines to control diseases in the United States. (cdc.gov)
- World Immunization Week will be celebrated both globally and regionally from 24 to 30 April 2019, using the slogan "Protected Together: Vaccines Work! (who.int)
- The Eastern Mediterranean Region has seen a remarkable increase in the number of people receiving vaccines in recent years, with more vaccines introduced and more countries eliminating diseases through immunization. (who.int)
- The goal of the Vaccine Education Center is to provide concise, accurate information on all aspects of vaccines and immunization. (accesskent.com)
- You have all or partial immunization records for this adolescent for Guard) vaccines given by your practice or other practices. (cdc.gov)
Childhood immunizations1
- CHILDHOOD IMMUNIZATION FILE 1992 Information on childhood immunizations was collected from adult respondents (often the mother) for one sample child under 6 years of age per National Health Interview Survey (NHIS) family with age-eligible children in the household. (cdc.gov)
Advisory Committee2
- In the United States, the Advisory Committee on Immunization Practices (ACIP) convened a working group to evaluate similar questions to those considered by WHO. (cdc.gov)
- The Centers for Disease Control and Prevention (CDC) sets the U.S. adult and childhood immunization schedules based on recommendations from the Advisory Committee on Immunization Practices (ACIP). (cdc.gov)
Vaccination1
- What are immunization and vaccination? (medlineplus.gov)
Access to immunization1
- In less than a generation, the African Region has made tremendous gains in increasing access to immunization and driving down child deaths. (who.int)
Diseases4
- The Immunization Branch of the California Department of Public Health provides leadership and support to public and private sector efforts to protect the population against vaccine-preventable diseases. (ca.gov)
- In addition to offering protection from preventable diseases, immunization also brings children and families into contact with health systems, providing an avenue for the delivery of other basic health services and laying the foundation for primary health care. (who.int)
- Summary of routine immunization and vaccine-preventable diseases surveillance data, based primarily on data for 2017 submitted through the WHO/UNICEF Joint Reporting Form on Immunization. (who.int)
- Immunisation is one of our strongest weapons against infectious diseases. (edu.au)
ACIP1
- In 2021, ACIP voted to approve a 2-dose preexposure rabies immunization series, with the proviso that either a third dose be given within 3 years, or a serological test be performed to document seroconversion. (cdc.gov)
Prevention2
- Rabies prevention presents unique issues for the travel medicine clinician, because it is the one infectious disease that can be prevented, either through a combination of pre- and postexposure immunizations or through postexposure treatment with rabies immune globulin (RIG) and vaccine. (cdc.gov)
- Prevention through immunization remains the best defense in the fight against pertussis. (medscape.com)
UNICEF1
- Dr. Ismaila Nuhu Maksha, immunization specialist at UNICEF, says polio is entirely preventable, but remains a problem in Africa. (voanews.com)
Preventable1
- August is National Immunization Awareness Month, which brings attention to the value of protecting yourself and your family from vaccine-preventable. (medlineplus.gov)
Schedules1
- The seeming complexity of the issues surrounding wound care, timing of administration, deviations from standard schedules, the cost of preexposure immunization, and the difficulty of finding vaccine and RIG while traveling can make the travel medicine practitioner's head spin. (cdc.gov)
Polio2
- Sierra Leone is kicking off the first of three massive immunization campaigns against polio. (voanews.com)
- Sierra Leone will launch a massive immunization campaign Saturday - part of a larger effort to control polio in 19 West African countries, including Guinea, Liberia and Nigeria. (voanews.com)
Tdap1
- Please note that in addition to compliance with all other required immunizations, children entering the 7th grade in Florida schools must have received one dose of the tetanus-diphtheria-pertussis (Tdap) vaccine. (browardschools.com)
Questionnaire1
- The immunization questionnaire was done before the physical examination, in the home, using the Computer-Assisted Personal Interviewing-CAPI (interviewer administered) system. (cdc.gov)
Traveler's1
- Because human and equine RIG often are unavailable in low- and middle-income countries, preexposure rabies immunization can facilitate the traveler's access to adequate postexposure rabies prophylaxis. (cdc.gov)
Citation1
- DSN: CC37.NHIS92.IMMUNIZE ABSTRACT 1992 NATIONAL HEALTH INTERVIEW SURVEY (NHIS) IMMUNIZATION PUBLIC USE DATA FILE Guidelines for Citation of Data With the goal of mutual benefit, the National Center for Health Statistics (NCHS) requests that recipients of data files cooperate in certain actions related to their use. (cdc.gov)
Infections1
- This is not good news - inadequate immunization means more infections and more deaths. (virology.ws)
Routine1
- Provides routine immunizations to students in Grades 1, 6, and 9 in school. (albertahealthservices.ca)
Hepatitis1
- questions IMQ.011 and IMQ.020) provides sample person interview data on immunization with the hepatitis A and hepatitis B vaccine for participants age 2 and above. (cdc.gov)
Schedule2
- In 2017-partly to address the lack of progress in decreasing rabies in the world-a World Health Organization (WHO) expert committee endorsed a 2-dose rabies preexposure immunization schedule in place of the previous 3-dose schedule. (cdc.gov)
- Below you can find our recommended immunization schedule and fact sheet. (cookchildrens.org)
Registry2
- Information on Michigan's immunization registry including contact lists. (accesskent.com)
- immunizations to your community or state registry? (cdc.gov)
Campus1
- The Student Health Center (Administration Building, A111) on campus offers immunizations and titer tests. (moorparkcollege.edu)
Public Health4
- Immunization is one of the most impactful and cost-effective public health interventions available, averting over 4 million deaths every year. (who.int)
- Each year, Alberta Health Services, Public Health reviews immunization records for students in grades 1, 6, and 9 to see what immunizations each student needs. (albertahealthservices.ca)
- Immunization saves millions of lives every year and is widely recognized as one of the most successful and cost-effective public health interventions. (who.int)
- The purpose of this database is to provide researchers, policymakers, and state and local public health practitioners with descriptive information concerning immunization-related state laws. (cdc.gov)
Center1
- Public Use File Documentation, National Health Interview Survey of Immunization, 1992 (machine readable data file and documentation), National Center for Health Statistics, Hyattsville, Maryland. (cdc.gov)
Requirements1
- Macalester College has established immunization requirements for its students to maintain the health and safety of our community. (macalester.edu)
Added value1
- In addition to its direct impact on the health of populations, immunization brings added value by reducing the burden of disease on individuals, families and communities, including through savings on medical expenses, as well as productivity and educational gains. (who.int)
Month1
- August is National Immunization Month. (cdc.gov)
Policy1
- It includes studies on vaccine cost-effectiveness, vaccine coverage disparities, and immunization policy, management and education. (ajpmonline.org)
Record2
People2
Provide3
- Prior to entering the 7th grade, all students must provide a Florida Certificate of Immunization (DH 680) stating that their immunizations are complete for 7th grade entry. (browardschools.com)
- Marie-Claude Bourgeois-Daigneault and her team at the CRCHUM are using mice to show how a combination of peptides and oncolytic viruses, used as an adjuvant, can provide effective immunization against cancer. (news-medical.net)
- Immunization expenditure data provide detailed analyses on country-level expenditure and financial flows for immunization. (who.int)
Form1
- Your child may need additional immunizations and/or you may just need to turn in the updated DH 680 form. (browardschools.com)
School1
- No immunizations will be given in school without consent from a parent or legal guardian. (albertahealthservices.ca)
Community2
- Immunization is a core component of the human right to health and an individual, community and government responsibility. (unicef.org)
- Helping our community understand the value of immunizations. (cookchildrens.org)
Protection1
- Protection of mice against Mycobacterium tuberculosis infection by immunization with aqueous fraction of Triton X-100-soluble cell wall proteins. (bvsalud.org)