History, 19th Century: Time period from 1801 through 1900 of the common era.History, 20th Century: Time period from 1901 through 2000 of the common era.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.History, 18th Century: Time period from 1701 through 1800 of the common era.Models, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Biological Evolution: The process of cumulative change over successive generations through which organisms acquire their distinguishing morphological and physiological characteristics.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Algorithms: A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.Computer Simulation: Computer-based representation of physical systems and phenomena such as chemical processes.Kinetics: The rate dynamics in chemical or physical systems.History, 21st Century: Time period from 2001 through 2100 of the common era.Models, Genetic: Theoretical representations that simulate the behavior or activity of genetic processes or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.History, 17th Century: Time period from 1601 through 1700 of the common era.Protein Binding: The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.Creativity: The ability to generate new ideas or images.Binding Sites: The parts of a macromolecule that directly participate in its specific combination with another molecule.Neurons: The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.Photic Stimulation: Investigative technique commonly used during ELECTROENCEPHALOGRAPHY in which a series of bright light flashes or visual patterns are used to elicit brain activity.Colonialism: The aggregate of various economic, political, and social policies by which an imperial power maintains or extends its control over other areas or peoples. It includes the practice of or belief in acquiring and retaining colonies. The emphasis is less on its identity as an ideological political system than on its designation in a period of history. (Webster, 3d ed; from Dr. J. Cassedy, NLM History of Medicine Division)Phylogeny: The relationships of groups of organisms as reflected by their genetic makeup.Nobel PrizeCell Line: Established cell cultures that have the potential to propagate indefinitely.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Philosophy: A love or pursuit of wisdom. A search for the underlying causes and principles of reality. (Webster, 3d ed)Models, Theoretical: Theoretical representations that simulate the behavior or activity of systems, processes, or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.Brain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.Evolution, Molecular: The process of cumulative change at the level of DNA; RNA; and PROTEINS, over successive generations.Models, Molecular: Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.Escherichia coli: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.Movement: The act, process, or result of passing from one place or position to another. It differs from LOCOMOTION in that locomotion is restricted to the passing of the whole body from one place to another, while movement encompasses both locomotion but also a change of the position of the whole body or any of its parts. Movement may be used with reference to humans, vertebrate and invertebrate animals, and microorganisms. Differentiate also from MOTOR ACTIVITY, movement associated with behavior.Philosophy, MedicalArtTranscription Factors: Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.History, Ancient: The period of history before 500 of the common era.Biology: One of the BIOLOGICAL SCIENCE DISCIPLINES concerned with the origin, structure, development, growth, function, genetics, and reproduction of animals, plants, and microorganisms.Reaction Time: The time from the onset of a stimulus until a response is observed.Models, Neurological: Theoretical representations that simulate the behavior or activity of the neurological system, processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.Proteins: Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Species Specificity: The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.Saccharomyces cerevisiae: A species of the genus SACCHAROMYCES, family Saccharomycetaceae, order Saccharomycetales, known as "baker's" or "brewer's" yeast. The dried form is used as a dietary supplement.DNA-Binding Proteins: Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.Transcription, Genetic: The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION.Protein Structure, Tertiary: The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.Thinking: Mental activity, not predominantly perceptual, by which one apprehends some aspect of an object or situation based on past learning and experience.Adaptation, Physiological: The non-genetic biological changes of an organism in response to challenges in its ENVIRONMENT.Genetic Determinism: The theory that human CHARACTER and BEHAVIOR are shaped by the GENES that comprise the individual's GENOTYPE rather than by CULTURE; ENVIRONMENT; and individual choice.Analysis of Variance: A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.Calcium: A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.Sequence Alignment: The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.Computational Biology: A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.Research: Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)DNA: A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).Psychomotor Performance: The coordination of a sensory or ideational (cognitive) process and a motor activity.Gene Expression Regulation: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.Models, Statistical: Statistical formulations or analyses which, when applied to data and found to fit the data, are then used to verify the assumptions and parameters used in the analysis. Examples of statistical models are the linear model, binomial model, polynomial model, two-parameter model, etc.Physiology: The biological science concerned with the life-supporting properties, functions, and processes of living organisms or their parts.Sequence Homology, Amino Acid: The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.Concept Formation: A cognitive process involving the formation of ideas generalized from the knowledge of qualities, aspects, and relations of objects.History, 16th Century: Time period from 1501 through 1600 of the common era.Protein Conformation: The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).Saccharomyces cerevisiae Proteins: Proteins obtained from the species SACCHAROMYCES CEREVISIAE. The function of specific proteins from this organism are the subject of intense scientific interest and have been used to derive basic understanding of the functioning similar proteins in higher eukaryotes.Social Values: Abstract standards or empirical variables in social life which are believed to be important and/or desirable.Drosophila: A genus of small, two-winged flies containing approximately 900 described species. These organisms are the most extensively studied of all genera from the standpoint of genetics and cytology.Carrier Proteins: Transport proteins that carry specific substances in the blood or across cell membranes.Drosophila Proteins: Proteins that originate from insect species belonging to the genus DROSOPHILA. The proteins from the most intensely studied species of Drosophila, DROSOPHILA MELANOGASTER, are the subject of much interest in the area of MORPHOGENESIS and development.Embryology: The study of the development of an organism during the embryonic and fetal stages of life.Selection, Genetic: Differential and non-random reproduction of different genotypes, operating to alter the gene frequencies within a population.Gene Expression Regulation, Developmental: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action during the developmental stages of an organism.Mice, Inbred C57BLSpace Perception: The awareness of the spatial properties of objects; includes physical space.Membrane Proteins: Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.Memory: Complex mental function having four distinct phases: (1) memorizing or learning, (2) retention, (3) recall, and (4) recognition. Clinically, it is usually subdivided into immediate, recent, and remote memory.Bacterial Proteins: Proteins found in any species of bacterium.Ecosystem: A functional system which includes the organisms of a natural community together with their environment. (McGraw Hill Dictionary of Scientific and Technical Terms, 4th ed)Software: Sequential operating programs and data which instruct the functioning of a digital computer.Cooperative Behavior: The interaction of two or more persons or organizations directed toward a common goal which is mutually beneficial. An act or instance of working or acting together for a common purpose or benefit, i.e., joint action. (From Random House Dictionary Unabridged, 2d ed)Genetic Variation: Genotypic differences observed among individuals in a population.Eugenics: The attempt to improve the PHENOTYPES of future generations of the human population by fostering the reproduction of those with favorable phenotypes and GENOTYPES and hampering or preventing BREEDING by those with "undesirable" phenotypes and genotypes. The concept is largely discredited. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Sexual Behavior, Animal: Sexual activities of animals.Action Potentials: Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.Folklore: The common orally transmitted traditions, myths, festivals, songs, superstitions, and stories of all peoples.Models, Psychological: Theoretical representations that simulate psychological processes and/or social processes. These include the use of mathematical equations, computers, and other electronic equipment.Temperature: The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.Environment: The external elements and conditions which surround, influence, and affect the life and development of an organism or population.Pattern Recognition, Visual: Mental process to visually perceive a critical number of facts (the pattern), such as characters, shapes, displays, or designs.Cell Membrane: The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells.Sequence Analysis, DNA: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.Feedback: A mechanism of communication within a system in that the input signal generates an output response which returns to influence the continued activity or productivity of that system.Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.Electrophysiology: The study of the generation and behavior of electrical charges in living organisms particularly the nervous system and the effects of electricity on living organisms.Behavior, Animal: The observable response an animal makes to any situation.Recombinant Fusion Proteins: Recombinant proteins produced by the GENETIC TRANSLATION of fused genes formed by the combination of NUCLEIC ACID REGULATORY SEQUENCES of one or more genes with the protein coding sequences of one or more genes.Ethical Theory: A philosophically coherent set of propositions (for example, utilitarianism) which attempts to provide general norms for the guidance and evaluation of moral conduct. (from Beauchamp and Childress, Principles of Biomedical Ethics, 4th ed)Mutagenesis, Site-Directed: Genetically engineered MUTAGENESIS at a specific site in the DNA molecule that introduces a base substitution, or an insertion or deletion.Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Orientation: Awareness of oneself in relation to time, place and person.Attitude to Health: Public attitudes toward health, disease, and the medical care system.Culture: A collective expression for all behavior patterns acquired and socially transmitted through symbols. Culture includes customs, traditions, and language.Cultural Evolution: The continuous developmental process of a culture from simple to complex forms and from homogeneous to heterogeneous qualities.United StatesCognition: Intellectual or mental process whereby an organism obtains knowledge.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Cloning, Molecular: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.Comprehension: The act or fact of grasping the meaning, nature, or importance of; understanding. (American Heritage Dictionary, 4th ed) Includes understanding by a patient or research subject of information disclosed orally or in writing.Attention: Focusing on certain aspects of current experience to the exclusion of others. It is the act of heeding or taking notice or concentrating.Congresses as Topic: Conferences, conventions or formal meetings usually attended by delegates representing a special field of interest.Psychological Theory: Principles applied to the analysis and explanation of psychological or behavioral phenomena.Attitude: An enduring, learned predisposition to behave in a consistent way toward a given class of objects, or a persistent mental and/or neural state of readiness to react to a certain class of objects, not as they are but as they are conceived to be.Biomechanical Phenomena: The properties, processes, and behavior of biological systems under the action of mechanical forces.Recombinant Proteins: Proteins prepared by recombinant DNA technology.Brain Mapping: Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.Membrane Potentials: The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).Thermodynamics: A rigorously mathematical analysis of energy relationships (heat, work, temperature, and equilibrium). It describes systems whose states are determined by thermal parameters, such as temperature, in addition to mechanical and electromagnetic parameters. (From Hawley's Condensed Chemical Dictionary, 12th ed)Mice, Transgenic: Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.Nuclear Proteins: Proteins found in the nucleus of a cell. Do not confuse with NUCLEOPROTEINS which are proteins conjugated with nucleic acids, that are not necessarily present in the nucleus.Politics: Activities concerned with governmental policies, functions, etc.Western World: A historical and cultural entity dispersed across the wide geographical area of Europe, as opposed to the East, Asia, and Africa. The term was used by scholars through the late medieval period. Thereafter, with the impact of colonialism and the transmission of cultures, Western World was sometimes expanded to include the Americas. (Dr. James H. Cassedy, NLM History of Medicine Division)Hydrogen-Ion Concentration: The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Developmental Biology: The field of biology which deals with the process of the growth and differentiation of an organism.DNA Primers: Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.Structure-Activity Relationship: The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.Science: The study of natural phenomena by observation, measurement, and experimentation.Reproduction: The total process by which organisms produce offspring. (Stedman, 25th ed)Drive: A state of internal activity of an organism that is a necessary condition before a given stimulus will elicit a class of responses; e.g., a certain level of hunger (drive) must be present before food will elicit an eating response.Synapses: Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.Portraits as Topic: Graphic representations, especially of the face, of real persons, usually posed, living or dead. (From Thesaurus for Graphic Materials II, p540, 1995)Drosophila melanogaster: A species of fruit fly much used in genetics because of the large size of its chromosomes.Optical Illusions: An illusion of vision usually affecting spatial relations.Social Behavior: Any behavior caused by or affecting another individual, usually of the same species.Mice, Knockout: Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Data Interpretation, Statistical: Application of statistical procedures to analyze specific observed or assumed facts from a particular study.Promoter Regions, Genetic: DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.Mathematics: The deductive study of shape, quantity, and dependence. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Neuronal Plasticity: The capacity of the NERVOUS SYSTEM to change its reactivity as the result of successive activations.Cell Differentiation: Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.Obsessive Behavior: Persistent, unwanted idea or impulse which is considered normal when it does not markedly interfere with mental processes or emotional adjustment.Choice Behavior: The act of making a selection among two or more alternatives, usually after a period of deliberation.Cues: Signals for an action; that specific portion of a perceptual field or pattern of stimuli to which a subject has learned to respond.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Questionnaires: Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.Hippocampus: A curved elevation of GRAY MATTER extending the entire length of the floor of the TEMPORAL HORN of the LATERAL VENTRICLE (see also TEMPORAL LOBE). The hippocampus proper, subiculum, and DENTATE GYRUS constitute the hippocampal formation. Sometimes authors include the ENTORHINAL CORTEX in the hippocampal formation.Psychophysics: The science dealing with the correlation of the physical characteristics of a stimulus, e.g., frequency or intensity, with the response to the stimulus, in order to assess the psychologic factors involved in the relationship.Magnetic Resonance Imaging: Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Light: That portion of the electromagnetic spectrum in the visible, ultraviolet, and infrared range.Anecdotes as Topic: Brief accounts or narratives of an incident or event.Morals: Standards of conduct that distinguish right from wrong.Birds: Warm-blooded VERTEBRATES possessing FEATHERS and belonging to the class Aves.HeLa Cells: The first continuously cultured human malignant CELL LINE, derived from the cervical carcinoma of Henrietta Lacks. These cells are used for VIRUS CULTIVATION and antitumor drug screening assays.Morphogenesis: The development of anatomical structures to create the form of a single- or multi-cell organism. Morphogenesis provides form changes of a part, parts, or the whole organism.Plagiarism: Passing off as one's own the work of another without credit.Color: The visually perceived property of objects created by absorption or reflection of specific wavelengths of light.Phosphorylation: The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.Decision Making: The process of making a selective intellectual judgment when presented with several complex alternatives consisting of several variables, and usually defining a course of action or an idea.Muscle, Skeletal: A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.Cell Nucleus: Within a eukaryotic cell, a membrane-limited body which contains chromosomes and one or more nucleoli (CELL NUCLEOLUS). The nuclear membrane consists of a double unit-type membrane which is perforated by a number of pores; the outermost membrane is continuous with the ENDOPLASMIC RETICULUM. A cell may contain more than one nucleus. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)Adaptation, Biological: Changes in biological features that help an organism cope with its ENVIRONMENT. These changes include physiological (ADAPTATION, PHYSIOLOGICAL), phenotypic and genetic changes.Fungal Proteins: Proteins found in any species of fungus.Transfection: The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.Nerve Tissue ProteinsMammals: Warm-blooded vertebrate animals belonging to the class Mammalia, including all that possess hair and suckle their young.Libraries: Collections of systematically acquired and organized information resources, and usually providing assistance to users. (ERIC Thesaurus, http://www.eric.ed.gov/ accessed 2/1/2008)Biological Transport: The movement of materials (including biochemical substances and drugs) through a biological system at the cellular level. The transport can be across cell membranes and epithelial layers. It also can occur within intracellular compartments and extracellular compartments.Cluster Analysis: A set of statistical methods used to group variables or observations into strongly inter-related subgroups. In epidemiology, it may be used to analyze a closely grouped series of events or cases of disease or other health-related phenomenon with well-defined distribution patterns in relation to time or place or both.Inventions: A novel composition, device, or process, independently conceived de novo or derived from a pre-existing model.Competitive Behavior: The direct struggle between individuals for environmental necessities or for a common goal.Adenosine Triphosphate: An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.Alleles: Variant forms of the same gene, occupying the same locus on homologous CHROMOSOMES, and governing the variants in production of the same gene product.Paranoid Disorders: Chronic mental disorders in which there has been an insidious development of a permanent and unshakeable delusional system (persecutory delusions or delusions of jealousy), accompanied by preservation of clear and orderly thinking. Emotional responses and behavior are consistent with the delusional state.Mutagenesis: Process of generating a genetic MUTATION. It may occur spontaneously or be induced by MUTAGENS.Gene Expression Profiling: The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.Neurology: A medical specialty concerned with the study of the structures, functions, and diseases of the nervous system.Genotype: The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.Plasmids: Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Feeding Behavior: Behavioral responses or sequences associated with eating including modes of feeding, rhythmic patterns of eating, and time intervals.Nucleic Acid Conformation: The spatial arrangement of the atoms of a nucleic acid or polynucleotide that results in its characteristic 3-dimensional shape.Bioethics: A branch of applied ethics that studies the value implications of practices and developments in life sciences, medicine, and health care.Biomedical Research: Research that involves the application of the natural sciences, especially biology and physiology, to medicine.Escherichia coli Proteins: Proteins obtained from ESCHERICHIA COLI.Cattle: Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.Judgment: The process of discovering or asserting an objective or intrinsic relation between two objects or concepts; a faculty or power that enables a person to make judgments; the process of bringing to light and asserting the implicit meaning of a concept; a critical evaluation of a person or situation.Protein Biosynthesis: The biosynthesis of PEPTIDES and PROTEINS on RIBOSOMES, directed by MESSENGER RNA, via TRANSFER RNA that is charged with standard proteinogenic AMINO ACIDS.Cricetinae: A subfamily in the family MURIDAE, comprising the hamsters. Four of the more common genera are Cricetus, CRICETULUS; MESOCRICETUS; and PHODOPUS.Conserved Sequence: A sequence of amino acids in a polypeptide or of nucleotides in DNA or RNA that is similar across multiple species. A known set of conserved sequences is represented by a CONSENSUS SEQUENCE. AMINO ACID MOTIFS are often composed of conserved sequences.Personal Autonomy: Self-directing freedom and especially moral independence. An ethical principle holds that the autonomy of persons ought to be respected. (Bioethics Thesaurus)History, Medieval: The period of history from the year 500 through 1450 of the common era.Models, Chemical: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.RNA: A polynucleotide consisting essentially of chains with a repeating backbone of phosphate and ribose units to which nitrogenous bases are attached. RNA is unique among biological macromolecules in that it can encode genetic information, serve as an abundant structural component of cells, and also possesses catalytic activity. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)Problem Solving: A learning situation involving more than one alternative from which a selection is made in order to attain a specific goal.Plants: Multicellular, eukaryotic life forms of kingdom Plantae (sensu lato), comprising the VIRIDIPLANTAE; RHODOPHYTA; and GLAUCOPHYTA; all of which acquired chloroplasts by direct endosymbiosis of CYANOBACTERIA. They are characterized by a mainly photosynthetic mode of nutrition; essentially unlimited growth at localized regions of cell divisions (MERISTEMS); cellulose within cells providing rigidity; the absence of organs of locomotion; absence of nervous and sensory systems; and an alternation of haploid and diploid generations.Freedom: The rights of individuals to act and make decisions without external constraints.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Bayes Theorem: A theorem in probability theory named for Thomas Bayes (1702-1761). In epidemiology, it is used to obtain the probability of disease in a group of people with some characteristic on the basis of the overall rate of that disease and of the likelihood of that characteristic in healthy and diseased individuals. The most familiar application is in clinical decision analysis where it is used for estimating the probability of a particular diagnosis given the appearance of some symptoms or test result.
This method uses the following idea. If a sound source and two microphones are arranged in a straight line, with the sound ... Other methods[edit]. In these methods the time measurement has been replaced by a measurement of the inverse of time (frequency ... Experimental methods[edit]. A range of different methods exist for the measurement of sound in air. ... Single-shot timing methods[edit]. The simplest concept is the measurement made using two microphones and a fast recording ...
Method[edit]. For the most part, these methods consist of the following elements, performed, more or less, in the following ... This is the idea of opportunity cost. Resources spent on risk management could have been spent on more profitable activities. ... The chosen method of identifying risks may depend on culture, industry practice and compliance. The identification methods are ... Methods, definitions and goals vary widely according to whether the risk management method is in the context of project ...
The idea behind Krylov methods. American Mathematical Monthly, 105(10):889-899, 1998. M. Petrik. An analysis of Laplacian ... This method uses graph information, but the construction of adjacency matrix makes this method hard to analyze. Dynamic ... There are two principal types of basis construction methods. The first type of methods are reward-sensitive, like Krylov and ... A good construction method should have the following characteristics: Small error bounds between the estimate and real value ...
Church, George (20 August 2013). "De-Extinction Is a Good Idea". Scientific American. Retrieved 9 April 2014. "Method: ... Produced idea of comparing fossil amino acid sequences with existing organism so that molecular evolution could be studied. ... Methods to match data sets include: maximum probability, minimum evolution (also known as neighbor-joining) which searches for ... The groups of species defined within a tree can also be later evaluated by statistical tests, such as the bootstrap method, to ...
John Krogstie and T.A. Halpin, Keng Siau (2004). Information Modeling Methods and Methodologies. Idea Group Inc (IGI), p.73. ...
Discussions with Pauli led Stueckelberg to drop the idea, however. It was rediscovered by Hideki Yukawa, who won a Nobel Prize ... However, besides being explicitly covariant, Stueckelberg's methods avoid vacuum bubbles.[8] Stueckelberg developed the vector ...
What Is Mathematics?: An Elementary Approach to Ideas and Methods. New York: Oxford University Press, 1996. p. 344. ... The idea of an isopleth map can be compared with that of a choropleth map.[8][9][10] ... The idea of lines that join points of equal value was rediscovered several times. The oldest known isobath (contour line of ... Contours are one of several common methods used to denote elevation or altitude and depth on maps. From these contours, a sense ...
Hershey: Idea Group. • Charles Ess, (2009) Digital Media Ethics. London: Polity. • Elizabeth Buchanan (forthcoming in 2010) " ... Johns, M. D., Chen, S., & Hall, G. J. (Eds.). (2004). Online Social Research: Methods, Issues & Ethics. Digital formations (p. ... quantitative and qualitative it does not necessarily follow strict Internet research ethics using the formal scientific method ...
Markham, A. (2006). Method as ethic, ethic as method. Journal of Information Ethics, 15(2), 37-55. Charles Ess and the ethics ... Hershey: Idea Group. Charles Ess, (2009) Digital Media Ethics. London: Polity. Elizabeth Buchanan (2010) "Internet Research ... Johns, M. D., Chen, S., & Hall, G. J. (Eds.). (2004). Online Social Research: Methods, Issues & Ethics. Digital formations (p. ... International Journal of Qualitative Methods 2010; 9(1): 27-39 PDF, 120 KB. Excerpt from the abstract: "... the author ...
A sub-heading of this dynamic is ideas and concepts such as beauty and the desire to survive through these. The eighth dynamic ... Scientology defined methods of correcting "misunderstoods" ("misunderstood word or symbol"). Scientologists have their own ... In Scientology doctrine, the idea of communication has a high status. In the book Sects, Cults, and Spiritual Communities, ... "Communication", believed to be the most important element of the triangle, is the exchange of ideas. Scientologists believe ...
"A laser ablation method for the synthesis of crystalline semiconductor nanowires". Science. 279: 208-11. 1998. doi:10.1126/ ... "World changing ideas 2015". Scientific American Special Report, 17 November 2015. "Top research of 2015: Flexible electronics ... "Stable long-term chronic brain mapping at the single neuron level". Nature Methods. 13: 875-82. 2016. doi:10.1038/nmeth.3969. " ... "Protein detection goes down to the wire". Nature Methods. "General strategy for biodetection in high ionic strength solutions ...
More objective testing methods were developed by Dr. Howard Andrew Knox to determine with increased accuracy whether an ... Some immigrants had no idea what X-ray machines did; others were fearful that their clothing - or the money sewn inside its ... The PHS used advanced methods in medicine as they developed. They used fluoroscopy and x-rays; there was an autoclave that ... The hospitals used the most advanced methods in medicine for the time. In 1912 the PHS installed a full scale laboratory, an ...
"The Big Idea: Ada Palmer". Whatever. John Scalzi. Retrieved 4 May 2017. "The Thirty-Five Compton Crook Award Winning Novels ... "Interview - Ada Palmer (Too Like The Lightning)". The Methods of Rationality Podcast. Retrieved 2 May 2017. Farell, Henry (10 ... Palmer and Hankins also argue that Lucretius' ideas directly influenced Niccolò Machiavelli and utilitarianism, because of the ...
ISBN 978-0-520-05294-9. Kregor, Jonathan (2010). "Models and methods". Liszt as Transcriber. pp. 9-40. ISBN 978-0-521-11777-7. ... Style and Idea: Selected Writings of Arnold Schoenberg. pp. 348-350. ...
Balmer, J.; Swisher, M.T. (2012). Diagramming the Big Idea: Methods for Architectural Composition. Taylor & Francis. p. 139. ...
Individual implementations of the message are called methods. The same idea was implemented in CommonLoops. New Flavors and ... Common Lisp can also retrieve individual methods from the generic function. FIND-METHOD finds the method from the generic ... find-method #'collide nil (list (find-class 'asteroid) (find-class 'spaceship))) #. Generic functions correspond roughly to ... Here we define a method for the generic function collide which is specialized for the classes asteroid (first parameter object- ...
Scarborough, Rowan (14-AUG-06). "Military at odds on intel methods; Pentagon ideas for Iraq ignored". The Washington Times. ...
This dictionary is heuristic in that it demonstrates various methods of forming new ideas and concepts. It reflects ... new methods and interdisciplinary approaches in the humanities; semiotics, language evolution and neologisms; and ideas and ... "Bank of New Ideas and Terms." In the 1990s, Epstein dealt with issues of postmodernism and the emergence of a new, future- ... for his electronic Bank of New Ideas; the International Essay Contest set up by Lettre International and Weimar - Cultural City ...
Though this method had triumphed in Cuba, Guevara saw it subsequently fail in Africa and Latin America. Laurent-Désiré Kabila ... Although the original approach was to mobilize and launch attacks from rural areas, many foco ideas were adapted into urban ... "Guerrilla War: A Method." Decree No. 261/75 Archived November 15, 2006, at the Wayback Machine.. NuncaMas.org, Decretos de ... While focalism drew from previous Marxist-Leninist ideas and the Maoist strategy of "protracted people's war", it also broke ...
Gain specialist knowledge and marketing methods. Reduce cost by sharing resources Share idea and responsibility. Gain access to ... Marketing economic alliance is in forms of combining industry or regional marketing method with resources and regional ... It is combining marketing knowledge, marketing examples, marketing practice, marketing idea together. Marketing alliance is the ... Online Business Ideas, Starting A Business, Joint Venture Partnership and More. p.17. Gibbs, R. and Humphries, A. (2009). ...
This method uses the following idea. If a sound source and two microphones are arranged in a straight line, with the sound ... This method uses a powder to make the nodes and antinodes visible to the human eye. This is an example of a compact ... The time of arrival between the signals (delay) reaching the different microphones (t). Then v = x/t. In these methods the time ... A range of different methods exist for the measurement of sound in air. The earliest reasonably accurate estimate of the speed ...
Leser, C. E. V. (1961). "A Simple Method of Trend Construction". Journal of the Royal Statistical Society. Series B ( ... Google Scholar IDEAS/RePEc. ...
Lanczos, Cornelius (1970). Space through the Ages: The Evolution of Geometrical Ideas from Pythagoras to Hilbert and Einstein. ... The method of coordinates (analytic geometry) was adopted by René Descartes in 1637.[3] At that time, geometric theorems were ... Gray, Jeremy (1989). Ideas of Space: Euclidean, Non-Euclidean and Relativistic (second ed.). Clarendon Press. ISBN 978- ... A similar idea occurs in mathematical logic: a theory is called categorical if all its models of the same cardinality are ...
Methods, and Applications. Idea Group Inc (IGI). p. 261. ISBN 1-59904-877-9. Lindback, Leif; Vladimir Vlassov; Shahab ...
Drum communication methods are not languages in their own right; they are based on actual natural languages. The sounds ... Firstly, a rhythm can represent an idea (or signal); secondly it can repeat the accentual profile of a spoken utterance; or ...
The IDEA provides for two methods of resolving disputes between parents and school districts. These include: 1. Mediation that ... the funds are disbursed to each local school district in accordance to the IDEA Part B standards and the funding method of the ... with the remaining 9 percent provided through federal IDEA funding.[13] States use a variety of methods of allocating funds to ... IDEA). IDEA requires states to provide special education and related services consistent with federal standards as a condition ...
With the emergence of two-photon microscopy and calcium imaging, we now have powerful experimental methods with which to test ... There are some tentative ideas regarding how simple mutually inhibitory functional circuits in these areas may carry out ... There have been some attempts to provide unified methods that bridge and integrate these levels of complexity.[33] ... Stereochemically detailed models of the acetylcholine receptor-based synapse with the Monte Carlo method, working at the time ...
His secretive methods and ideas were revealed. A few months later, a devastating critique of Lysenko was made public. ... His ideas were also shaped with the caution to disprove other claims made by his fellow geneticists at the time. His ideas and ... Lysenko's ideas were for the most part his own and not directly derived from any already established ideas such as Mendelian ... Lepeshinskaya recognized common ground between her ideas and Lysenko's. By combining both of their ideas it was possible to ...
Erics idea was to configure a light microscope so that only a small number of fluorescent molecules in the cell light up at ... Betzig and Moerner, working separately, laid the foundation for single-molecule microscopy. This method relies upon the ... Betzig used this method, called PALM (photoactivated localization microscopy), for the first time in 2006. ...
IDEA Method. E-Gull Method. Smack~M~BackDown 2003 The Write Way. ... The IDEA Method. Step1. If using 120mg (12hr)or 240mg (24hr), An outer coating exists that would be better if its removed ... The E-Gull Method. Step1. Crush Non Dry Matrix Formulation (NDMF) pseudo-ephedrine (p-fed ) pills to a powder and pass through ... The first phase of both these methods is a wash only....NOT A SOAK! If the pills are allowed to sit in solution for longer than ...
The Finite Element Method (FEM) is a popular numerical technique used for solving boundary-valued problems in various areas of ... Finite Element Method (idea). See all of Finite Element Method, no other writeups in this node. ... The Finite Element Method (FEM) is a popular numerical technique used for solving boundary-valued problems in various areas of ... Historical parallels between World War I and the Thirty Years War (idea) by Chord. ...
Two cases important to entities that file business method patents software patents and medical diagnostics are Bilski v. Kappos ... IP: Business methods, diagnostics and abstract ideas. The Supreme Court has taken an increased interest in patent cases in ... However, methods and products applying abstract ideas, physical phenomena and laws of nature to perform a real-world function ... The board (citing Bilski) concluded that the method is directed to an abstract idea of matching criteria and is only nominally ...
Many thanks to Denis Jevon from the UK for this idea. Hugs, Gary By Denis Jevon EFT A... ... A Useful Method for Private Tapping Note: This is one of 3,000 articles written prior to the updated Gold Standard (Official ... The "7 Whys" method for getting to core issues. *An extraordinary account of tapping on a prenatal core issue -- or how to ... Further, Gary Craig is not a licensed health professional and offers EFT and all other methods on this website as an ordained ...
The method can be as simple as imaging a feather tickling the amygdala, which automatically shunts neurochemical activity ... Use our methods - Buy strong neodymium magnets (industrial, school, home) - supermagnete - ZooWhiz , Maths, Reading, Word ...
A method for using EFT regarding the difficult people in your life. Note: This is one of 3,000 articles written prior to the ... Methods for getting to deep issues, even in a group setting. *Using silent tapping in cases where speaking out loud is too ... The "7 Whys" method for getting to core issues. *An extraordinary account of tapping on a prenatal core issue -- or how to ... Articles & Ideas*Being Specific*How to apply EFT when there are no clear, specific memories to tap on ...
Easy method to make yogurt in home This dairy food that has existed for centuries is full of diet, assists digestion and ... Consuming yogurt is definitely a tasty and easy method of making certain you obtain the perfect levels of these vitamins, also ...
The topological data analysis tool, Mapper, was used to analyze simulations of an RNA hairpin and provided structural evidence on multiple intermediate states along the path. Mapper, parameters, and RNA conformaitons to reproduce the results are provided
... posted in Research Idea, Design and Collaboration: Hi everyone !! I just find a correlation about my protein and telomeres ... What method is the best to measure Telomeres? - ... What method is the best to measure Telomeres?. Started by ...
Storm the Brain! 15 Methods to Get Unstuck, Prompt Ideas, and Solve Problems. Column by Annie Neugebauer November 3, 2017 5 ... So many great ideas Ive never used! Love that you added the why for each idea. Very helpful, thank you :-) ... I love the idea of writing down what scares you so you have a tangible problem to address and solve, and the word storm seems ... Keep an ideas file full of every random story/poem/novel/article concept, snippet, or quote you ever think of. Not only will ...
... help needed hybrid idea ideas intermediate last layer algorithms mcm method method new method ollcp pang petrus petrus method ... Calculating Method/Substep Efficiency. Puzzle Theory. 26. Oct 20, 2014. Method Substeps and Subgroups. Puzzle Theory. 4. Nov 19 ... I really like the idea of mixing in L5C with Roux. The method I use for L7E in the latest LMCF still isnt optimal, and so I ... I really like the idea of mixing in L5C with Roux. The method I use for L7E in the latest LMCF still isnt optimal, and so I ...
Statistical Ideas and Methods (with CD-ROM and Internet Companion for Statistics) (9780495122500) by Jessica M. Utts; Robert F ... Emphasizing the conceptual development of statistical ideas, STATISTICAL IDEAS AND METHODS actively engages students and ... Statistical Ideas and Methods (with CD-ROM and Internet Companion for Statistics) ISBN 13: 9780495122500. ... 4. Statistical Ideas and Methods (with CD-ROM and Internet Companion for Statistics) Utts, Jessica M., Heckard, Robert F. ...
Methods to make your pattern or stencil more durable:. Mylar or Acetate sheets. Print or trace your design onto paper and tape ... This method also works with dyeing fabric and you can watch our video about how to make this geometric design for a pillow. ... A more effective way to do this method is with a wood burning tool and a Laser Jet printout using the round flat attachment (it ... This method also works for making lettered signs with a wood burning tool. See how to make one here. ...
Clinical Assessment of Renal Function: New Methods, Old Ideas World Small Animal Veterinary Association World Congress ... 8. Finco DR, et al: Simple, accurate method for clinical estimation of glomerular filtration rate in the dog. Am J Vet Res 42: ... Although measurement methods will alter exact values, normal ranges for GFR are generally 3.5-4.5 ml/min/kg body weight in dogs ... 4. Brown SA, et al: Evaluation of a single injection method, using iohexol, for estimating glomerular filtration rate in cats ...
This shop Mixed Methods Research in Poverty and Vulnerability: Sharing Ideas and Learning has of at least three assets. Each of ... shop Mixed Methods Research in Poverty and Vulnerability: Sharing Ideas and on your background or Supersize to the tribe change ... Shop Mixed Methods Research In Poverty And Vulnerability: Sharing Ideas And Learning Lessons. QuitSmart® was created by Dr. ... Shop Mixed Methods Research In Poverty And Vulnerability: Sharing Ideas And Learning Lessons. by Kathleen 3.7 ...
3 Methods For Home Furnishing Ideas You Need To Use Today. Posted on 02/10/2019. by Dolly Thornton ... Tagged furnishing, ideas. Post navigation. Previous post The Trick For Home Contractor Unveiled in 5 Easy Steps ... That is in a method as if they are altering their wardrobe. Emergence of newest designs by number of home furnishing suppliers ... Detail by detail Notes on Home Furnishing Ideas In Step-by-step Order. Posted on 22/08/2019. ...
Jessica Bomarito & Jeffrey W. The Ideas, Images, And will be used to online robe initiative. Sunday Ideas, Images, And Methods ... This is a Ideas, Images, And Methods Of Portrayal: Insights Into of 27 easy textbooks of support Government you would view in a ... For Ideas, Images, And Methods, in attacks 1 through 13 we have the ia needed by little mechanisms in Egypt who were their ... Send a private message to Sajen You can do the Ideas, Images, And Methods Of to use found with Click or work, and you can be ...
Statistical Methods For Survival Data Analysis Is Anideal Text For Upper Undergraduate And Graduate Level Courses Onsurvival ... Statistical methods for survival data analysis is an ideal text for upper undergraduate and graduate level courses on survival ... Statistical methods for survival data analysis is anideal text for upper undergraduate and graduate level courses onsurvival ... The author of the previous editions of statistical methods for survival data analysis professor lee is a fellow of the american ...
Age Reversing Epidermis Treatment method - Some Ideas. July 12, 2018. July 4, 2018. admin Beauty ...
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Some Ideas For Metrology to Extend Capability and Attract Investors and Users from Methods Development Communities Art Ruggles ... Some Ideas For Metrology to Extend Capability and Attract Investors and Users from Methods Development Communities - Some Ideas ... Some Ideas For Metrology to Extend Capability and Attract Investors and Users from Methods Development Communities. ... Some Ideas For Metrology to Extend Capability and Attract Investors and Users from Methods Development Communities. 1. Some ...
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Materials and methods. Clinical trials registered in the ClinicalTrials.gov database, EU Clinical Trials Register and- ... This corresponds with the "idea" and "development" stages of the IDEAL framework [15, 16, 17]. The significant number of ... Methods. We surveyed clinical trials registered in 15 primary registries worldwide, including ClinicalTrials.gov. All trials ... The IDEAL framework divides innovations in surgery and interventional procedures into five phases: (1) idea, (2) development, ( ...
... which focused on IDEA data, compared two independent methods for calculating the trend slope of ASD prevalence versus birth ... dFor all IDEA data, the birth year span is 1994-2003, the tracking age is 8 years old and the 2011 IDEA snapshot age range is 8 ... All 2011 IDEA bsnap trend slopes presented in Table 2 are significantly , 0, suggesting the IDEA data are inconsistent with the ... Comparison of CDDS, IDEA and ADDM 8 Year-Old Prevalence in 16 States. Expanding the analysis to the IDEA and ADDM datasets ...
  • Bootstrap methods are computer-intensive statistical methods of analysis that use simulation to calculate standard errors, confidence intervals and significance tests. (worldcat.org)
  • This book gives a broad and up-to-date coverage of bootstrap methods, with numerous applied examples, developed in a coherent way with the necessary theoretical basis. (cambridge.org)
  • Statisticians with little or no familiarity with the bootstrap will find Bootstrap Methods and Their Application to be a thorough introduction to its use in solving real-world problems. (cambridge.org)
  • Through the numerous exercises, practicals and examples the reader obtains a good understanding for the strength of bootstrap methods, the problems for which they work and how to avoid their pitfalls. (cambridge.org)
  • I strongly recommend this book to anybody who uses, or wishes to use, bootstrap methods. (cambridge.org)
  • Notwithstanding the mandate from Congress, the Supreme Court has said that subject matter that is ineligible for patenting includes abstract ideas, natural phenomena and laws of nature/natural correlations. (law.com)
  • However, methods and products applying abstract ideas, physical phenomena and laws of nature to perform a real-world function may well be patentable. (law.com)
  • The court found that the Bilski method of optimizing a fixed bill system for energy markets was an unpatentable abstract idea in view of the following guidelines for determining whether the method claim was ultimately directed solely to an abstract idea. (law.com)
  • and whether a general concept (which could also be recognized in such terms as a principle, theory, plan or scheme) is involved in executing the steps of the method. (law.com)
  • In Mayo , the Supreme Court was challenged with determining if claims to a method of improving efficacy of a drug treatment by the steps of administering a drug and determining the levels of drug in the blood to determine whether the drug is at a toxic level were patent-eligible subject matter. (law.com)
  • Factors weighing against patentability in Mayo include that the method contained steps that were well-understood and previously engaged in by those in the field and added nothing specific to the natural principle. (law.com)
  • The examiner originally rejected the claims asserting that the associated machine did not carry out the steps of the method and transform the garment, and that the "providing" steps were simply general concepts. (law.com)
  • The proposed method for optimization comprises six steps. (google.es)
  • Statistical methods for survival data analysis is anideal text for upper undergraduate and graduate level courses onsurvival data analysis the book is also an excellent resource forbiomedical investigators statisticians and epidemiologists aswell as researchers in every field in which the analysis ofsurvival data plays a role. (cash-advance3.ca)
  • The author of the previous editions of statistical methods for survival data analysis professor lee is a fellow of the american statistical association and member of the society for epidemiological research and the american diabetes association. (cash-advance3.ca)
  • This is why you need a single place where you can reflect your ideas and iterate to enrich, evaluate and prioritize them. (medium.com)
  • They need to operate in an ' actionable innovation ' mode where, on one hand, employees actively participate in the idea generation process and on the other hand, executives constantly evaluate ideas and business opportunities in an experimentation-driven setup. (medium.com)
  • Vendors are primary customer, They bring their own test sections and may develop their own methods. (powershow.com)
  • Students will be exposed to competing perspectives on some of the most fundamental problems facing thinking individuals throughout the centuries, and will be strongly encouraged to develop reflective awareness of the ways through which seemingly distant ideas shape the economic organisation of contemporary societies. (southampton.ac.uk)
  • If you lack ideas, just watch TV, read the Internet posts, and magazines and you will definitely find many different ideas to develop in your academic paper. (essayshark.com)
  • Therefore, this paper proposes an effective intrinsic mode function selection method for the approximate entropy of empirical mode decomposition considering the characteristics of the frequency distribution of road and vehicle information and the unsteady and nonlinear characteristics of the driver closed-loop driving system in vehicle driving state data. (hindawi.com)
  • Logistic regression analysis found smoking-related knowledge, attitudes, behaviors and sociodemographic factors affect having smoking cessation idea. (mdpi.com)
  • The main purpose of these two methods are to effectively isolate polymer inactives and some antihistamines included in over-the-counter ( OTC ) medicines containing pseudo-ephedrine hydrochloride ( p-fed.hcl. (erowid.org)
  • The ability to capture the idea effectively in as few words as possible. (google.com)
  • International Journal of Advance Innovations , Thoughts & Ideas (IJAITI) is a peer reviewed international journal and this is a unique platform which disseminates information on the novel concepts and novel application of existing concept. (omicsonline.org)
  • But now that the center has gotten started, many researchers and economists are disturbed that it is not using randomized clinical trials, the rigorous method that is widely considered the gold standard in medical and social science research. (nytimes.com)
  • Objective To examine how poor reporting and inadequate methods for key methodological features in randomised controlled trials (RCTs) have changed over the past three decades. (bmj.com)
  • Main outcomes measures We considered the proportions of trials rated by review authors at unclear and high risk of bias as surrogates for poor reporting and inadequate methods, respectively. (bmj.com)
  • After excluding trials at unclear risk of bias, use of inadequate methods also decreased over time: from 14.8% to 4.6% for sequence generation and from 32.7% to 11.6% for allocation concealment. (bmj.com)
  • Two cases important to entities that file business method patents, software patents and medical diagnostics are Bilski v. Kappos and Mayo Collaborative Services v. Prometheus Laboratories, Inc . These cases addressed claimed processes that apply algorithms and natural phenomena, and what can be considered patent-eligible subject matter. (law.com)
  • This part of the processes addresses the ideas that we think they have about us, it also gives us a chance to step outside ourselves and see ourselves from someone else's perspective. (emofree.com)
  • The Berlin method works so well because it uses the same processes at work on a natural reef to keep the system healthy , rather than relying on more artificial means. (everything2.com)
  • Our goal in this venue is to keep up to date with current research in the field of Gastroenterology and Hepatology for the purposes of not only facilitating education, but to also stimulate potential ideas for future clinical and translational research. (rochester.edu)
  • The most common fatigue detection method is the analysis of driver behavior, that is, to determine whether the driver is tired by recording and analyzing the behavior characteristics of steering wheel and brake. (hindawi.com)
  • Following practices like ' rapid prototyping ' and ' fail fast ', ideas can be quickly tested from real users, in order to make informed decisions, as soon as possible and at minimum cost. (medium.com)
  • A lot of software makers are generally seeking methods to make Currency trading less complicated and much more rewarding. (sooperarticles.com)
  • There is no 100% guaranteed method to succeed in selling, but you can make it a lot easier to sell more, and for your people to sell more too. (businessballs.com)
  • here are a few of our favorite gift ideas. (aagiftsandbaskets.com)
  • Enter: this list of the best gift ideas for coworkers. (yahoo.com)
  • Not only do we have the top holiday gift ideas, but we've also provided a thorough list of every other fantastic gift that will surely put a smile on anyone's face. (mesothelioma.com)
  • In fact, failure is part of the overall innovation process, since it can feedback significant insights, results, metrics, and findings for the idea itself, the prototype or even the process. (medium.com)
  • Two cases important to entities that file business method patents, software patents and medical diagnostics are Bilski v. Kappos and Mayo Collaborative Services v. Prometheus Laboratories, Inc. (law.com)
  • Those in the business-method area and in medical diagnostics/pharmaceuticals are still left wondering what types of claims will be available to cover their new and useful inventions since the March 2012 Mayo decision. (law.com)
  • top small business blogs ( http://singapore-press.club ) fashion bloggers top OLowering of cholesterol: Τhese Cool website Ideas helps in reducing cholesterol leveⅼs in the body as it has high concentration of antioxidants. (stock-options-picks.com)
  • and second, to motivate students to reflect on the relevance of these big ideas for their own lives, and for the wider challenges of the contemporary business world. (southampton.ac.uk)
  • The book Testing Business Ideas by David Bland and Alex Osterwalder provides experiments that can be used to find out if your product ideas are desirable, viable and feasible. (infoq.com)
  • You need a simple but consistent process to maintain your personal ideas backlog. (medium.com)
  • Enlarge Tent to Include Methods Development community (multiphysics simulation and CFD), with more government support. (powershow.com)
  • A telecommunications system and method is disclosed for providing a substantially immediate electronic receipt after a consumer has made a purchase. (google.com)
  • In such a case, it is usual to increase the quota until the number of candidates elected is equal to the number of seats available, in effect changing the voting system to the Jefferson apportionment formula (see D'Hondt method). (wikipedia.org)
  • But, when it comes to an ideation channel, you need some serious technology to capture, process, and diffuse ideas within your corporation. (medium.com)
  • Character Ideas for Fiction Writers (Ideas for Writers Book 1) (English Edition) eBook: Dave Haslett: Amazon.com.mx: Tienda Kindle. (101ng.tk)
  • How to Create Bestselling Book Ideas. (101ng.tk)
  • this had inspired a few book ideas. (101ng.tk)
  • This book includes S-Plus software for implementing ideas contained in the text. (worldcat.org)
  • Included with the book is a disk of purpose-written S-Plus programs for implementing the methods described in the text. (cambridge.org)
  • Book title: By Their Own Young Hand: Deliberate Self-Harm and Suicidal Ideas in Adolescents. (questia.com)
  • A teacher page that describes the project and provides helpful ideas to. (101ng.tk)
  • This mainly applies to configuring third party/library methods as well as projects that still have to use Java 1.4. (jetbrains.com)
  • Population dynamics provides an interesting field for the application of a plethora of ideas from statistical mechanics. (mdpi.com)
  • Since the method of judging the driver's dangerous driving condition based on physiological information needs to install the sensor on the driver and the application requires accurate correction or debugging of the sensor, it can not be widely used in practice. (hindawi.com)
  • The review starts with an exhaustive coverage of various methods ranging from early measures of risk-adjusted return to more recent methods including the rating given by ASSIRT, a financial services organisation that assess managed investment in Australia. (repec.org)
  • Le groupe de bénévoles médicaux Altababa a été créé par des médecins soudanais en exercice en Arabie saoudite souhaitant contribuer à l'amélioration des services cliniques et à la formation dans leur pays d'origine. (who.int)
  • Remember, coming up with new healthy dinner ideas doesn't have to mean spending more time cooking up elaborate recipes. (vitamix.com)
  • To communicate through jogging, running and competing that the end of world hunger is an idea whose time has come. (newint.org)
  • Conclusions Poor reporting and inadequate methods have decreased over time, especially for sequence generation and allocation concealment. (bmj.com)
  • The module presents a 'big history' of ideas to expose students to the major schools of thought in philosophy, politics and early thinkers of social science (economics, sociology, psychology, anthropology). (southampton.ac.uk)
  • Once you teach your students the Steal and Slide method, they can use it for any word problems in your math series or standardize tests! (fernsmithsclassroomideas.com)
  • This study examined and compared students' understanding of nature of science (NOS) with 521 Grade 8 Canadian and Korean students using a mixed methods approach. (ed.gov)
  • NoEstimates is a set of ideas that can be applied to any software development endeavor with the goal of re-focusing that software development on value delivered, as opposed to following a pre-determined plan defined by tasks + estimates. (infoq.com)
  • 8. A computer software program product, implementing a method of claim 1 when executing when running on a computing device. (google.es)
  • The Finite Element Method ( FEM ) is a popular numerical technique used for solving boundary-valued problems in various areas of mechanical and electrical engineering. (everything2.com)
  • Overall the present findings indicate that no statistically significant correlation between the education level and quitting smoking idea exists among young adult male smokers in China. (mdpi.com)
  • Explores the history of determining the value of PI from Archimedes to present computer methods. (ed.gov)
  • At present, the identification methods of dangerous driving are identification method based on physiological information, identification method based on driver operation information, machine vision recognition method, and vehicle motion identification method. (hindawi.com)
  • International journal of Advance Innovations, Thoughts & Ideas publishes articles that cover all aspects of Innovations in basic, Engineering, Management fields. (omicsonline.org)
  • The basic idea of using User Stories instead of the traditional Work-Breakdown-Structure is already one step in the direction of #NoEstimates. (infoq.com)
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