Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN.
Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.
Hypertension due to RENAL ARTERY OBSTRUCTION or compression.
A condition of markedly elevated BLOOD PRESSURE with DIASTOLIC PRESSURE usually greater than 120 mm Hg. Malignant hypertension is characterized by widespread vascular damage, PAPILLEDEMA, retinopathy, HYPERTENSIVE ENCEPHALOPATHY, and renal dysfunction.
A condition in pregnant women with elevated systolic (>140 mm Hg) and diastolic (>90 mm Hg) blood pressure on at least two occasions 6 h apart. HYPERTENSION complicates 8-10% of all pregnancies, generally after 20 weeks of gestation. Gestational hypertension can be divided into several broad categories according to the complexity and associated symptoms, such as EDEMA; PROTEINURIA; SEIZURES; abnormalities in BLOOD COAGULATION and liver functions.
A condition in which the intraocular pressure is elevated above normal and which may lead to glaucoma.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
The short wide vessel arising from the conus arteriosus of the right ventricle and conveying unaerated blood to the lungs.
A strain of Rattus norvegicus with elevated blood pressure used as a model for studying hypertension and stroke.
A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC
Increased pressure within the cranial vault. This may result from several conditions, including HYDROCEPHALUS; BRAIN EDEMA; intracranial masses; severe systemic HYPERTENSION; PSEUDOTUMOR CEREBRI; and other disorders.
Techniques for measuring blood pressure.
A strain of Rattus norvegicus used as a normotensive control for the spontaneous hypertensive rats (SHR).
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
A steroid metabolite that is the 11-deoxy derivative of CORTICOSTERONE and the 21-hydroxy derivative of PROGESTERONE.
Enlargement of the RIGHT VENTRICLE of the heart. This increase in ventricular mass is often attributed to PULMONARY HYPERTENSION and is a contributor to cardiovascular morbidity and mortality.
Sodium chloride used in foods.
Method in which repeated blood pressure readings are made while the patient undergoes normal daily activities. It allows quantitative analysis of the high blood pressure load over time, can help distinguish between types of HYPERTENSION, and can assess the effectiveness of antihypertensive therapy.
The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.
A pyrrolizidine alkaloid and a toxic plant constituent that poisons livestock and humans through the ingestion of contaminated grains and other foods. The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. Significant attenuation of the cardiopulmonary changes are noted after oral magnesium treatment.
The co-occurrence of pregnancy and a cardiovascular disease. The disease may precede or follow FERTILIZATION and it may or may not have a deleterious effect on the pregnant woman or FETUS.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.
A BLOOD PRESSURE regulating system of interacting components that include RENIN; ANGIOTENSINOGEN; ANGIOTENSIN CONVERTING ENZYME; ANGIOTENSIN I; ANGIOTENSIN II; and angiotensinase. Renin, an enzyme produced in the kidney, acts on angiotensinogen, an alpha-2 globulin produced by the liver, forming ANGIOTENSIN I. Angiotensin-converting enzyme, contained in the lung, acts on angiotensin I in the plasma converting it to ANGIOTENSIN II, an extremely powerful vasoconstrictor. Angiotensin II causes contraction of the arteriolar and renal VASCULAR SMOOTH MUSCLE, leading to retention of salt and water in the KIDNEY and increased arterial blood pressure. In addition, angiotensin II stimulates the release of ALDOSTERONE from the ADRENAL CORTEX, which in turn also increases salt and water retention in the kidney. Angiotensin-converting enzyme also breaks down BRADYKININ, a powerful vasodilator and component of the KALLIKREIN-KININ SYSTEM.
A hormone secreted by the ADRENAL CORTEX that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.
A condition caused by the overproduction of ALDOSTERONE. It is characterized by sodium retention and potassium excretion with resultant HYPERTENSION and HYPOKALEMIA.
The number of times the HEART VENTRICLES contract per unit of time, usually per minute.
A condition marked by raised intracranial pressure and characterized clinically by HEADACHES; NAUSEA; PAPILLEDEMA, peripheral constriction of the visual fields, transient visual obscurations, and pulsatile TINNITUS. OBESITY is frequently associated with this condition, which primarily affects women between 20 and 44 years of age. Chronic PAPILLEDEMA may lead to optic nerve injury (see OPTIC NERVE DISEASES) and visual loss (see BLINDNESS).
Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
Sodium or sodium compounds used in foods or as a food. The most frequently used compounds are sodium chloride or sodium glutamate.
Elements of limited time intervals, contributing to particular results or situations.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Period of contraction of the HEART, especially of the HEART VENTRICLES.
A diet which contains very little sodium chloride. It is prescribed by some for hypertension and for edematous states. (Dorland, 27th ed)
Drugs used to cause dilation of the blood vessels.
Agents that promote the excretion of urine through their effects on kidney function.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Inbred rats derived from Sprague-Dawley rats and used for the study of salt-dependent hypertension. Salt-sensitive and salt-resistant strains have been selectively bred to show the opposite genetically determined blood pressure responses to excess sodium chloride ingestion.
A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
The circulation of the BLOOD through the LUNGS.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Narrowing or occlusion of the RENAL ARTERY or arteries. It is due usually to ATHEROSCLEROSIS; FIBROMUSCULAR DYSPLASIA; THROMBOSIS; EMBOLISM, or external pressure. The reduced renal perfusion can lead to renovascular hypertension (HYPERTENSION, RENOVASCULAR).
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
A syndrome of persistent PULMONARY HYPERTENSION in the newborn infant (INFANT, NEWBORN) without demonstrable HEART DISEASES. This neonatal condition can be caused by severe pulmonary vasoconstriction (reactive type), hypertrophy of pulmonary arterial muscle (hypertrophic type), or abnormally developed pulmonary arterioles (hypoplastic type). The newborn patient exhibits CYANOSIS and ACIDOSIS due to the persistence of fetal circulatory pattern of right-to-left shunting of blood through a patent ductus arteriosus (DUCTUS ARTERIOSUS, PATENT) and at times a patent foramen ovale (FORAMEN OVALE, PATENT).
Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.
A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
Phenomenon where increased BLOOD PRESSURE readings taken in non-clinical settings (e.g., HOME BLOOD PRESSURE MONITORING) do not replicate in clinical settings.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
Blood pressure levels that are between normotension and hypertension. Individuals with prehypertension are at a higher risk for developing cardiovascular diseases. Generally, prehypertension is defined as SYSTOLIC PRESSURE of 131-139 mm Hg and/or DIASTOLIC PRESSURE of 81-89 when the optimal is 120/80 mm Hg. For diabetics and other metabolism diseases the prehypertension is around 110-129/70-79 mm Hg.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
An alpha-globulin of about 453 amino acids, depending on the species. It is produced by the liver and secreted into blood circulation. Angiotensinogen is the inactive precursor of natural angiotensins. Upon successive enzyme cleavages, angiotensinogen yields angiotensin I, II, and III with amino acids numbered at 10, 8, and 7, respectively.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
Relatively complete absence of oxygen in one or more tissues.
A ubiquitous sodium salt that is commonly used to season food.
A branch of the abdominal aorta which supplies the kidneys, adrenal glands and ureters.
Individuals whose ancestral origins are in the continent of Africa.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.
A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)
The presence of albumin in the urine, an indicator of KIDNEY DISEASES.
Pathological processes of the KIDNEY or its component tissues.
Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.
A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
Agents that inhibit SODIUM CHLORIDE SYMPORTERS. They act as DIURETICS. Excess use is associated with HYPOKALEMIA.
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Agents that antagonize ANGIOTENSIN II TYPE 1 RECEPTOR. Included are ANGIOTENSIN II analogs such as SARALASIN and biphenylimidazoles such as LOSARTAN. Some are used as ANTIHYPERTENSIVE AGENTS.
The physiological widening of BLOOD VESSELS by relaxing the underlying VASCULAR SMOOTH MUSCLE.
Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.
A subtype of bone morphogenetic protein receptors with low affinity for BONE MORPHOGENETIC PROTEINS. They are constitutively active PROTEIN-SERINE-THREONINE KINASES that can interact with and phosphorylate TYPE I BONE MORPHOGENETIC PROTEIN RECEPTORS.
The physiological narrowing of BLOOD VESSELS by contraction of the VASCULAR SMOOTH MUSCLE.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI=weight (kg)/height squared (m2). BMI correlates with body fat (ADIPOSE TISSUE). Their relationship varies with age and gender. For adults, BMI falls into these categories: below 18.5 (underweight); 18.5-24.9 (normal); 25.0-29.9 (overweight); 30.0 and above (obese). (National Center for Health Statistics, Centers for Disease Control and Prevention)
A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin.
The blood pressure in the ARTERIES. It is commonly measured with a SPHYGMOMANOMETER on the upper arm which represents the arterial pressure in the BRACHIAL ARTERY.
Post-systolic relaxation of the HEART, especially the HEART VENTRICLES.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
Drugs used to cause constriction of the blood vessels.
Conditions or pathological processes associated with the disease of diabetes mellitus. Due to the impaired control of BLOOD GLUCOSE level in diabetic patients, pathological processes develop in numerous tissues and organs including the EYE, the KIDNEY, the BLOOD VESSELS, and the NERVE TISSUE.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).
A cardioselective beta-1 adrenergic blocker possessing properties and potency similar to PROPRANOLOL, but without a negative inotropic effect.
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
Excision of kidney.
The circulation of the BLOOD through the vessels of the KIDNEY.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
The main trunk of the systemic arteries.
The vessels carrying blood away from the heart.
A direct-acting vasodilator that is used as an antihypertensive agent.
The nonstriated involuntary muscle tissue of blood vessels.
The presence of proteins in the urine, an indicator of KIDNEY DISEASES.
An angiotensin receptor subtype that is expressed at high levels in a variety of adult tissues including the CARDIOVASCULAR SYSTEM, the KIDNEY, the ENDOCRINE SYSTEM and the NERVOUS SYSTEM. Activation of the type 1 angiotensin receptor causes VASOCONSTRICTION and sodium retention.
A benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic.
An eicosanoid, derived from the cyclooxygenase pathway of arachidonic acid metabolism. It is a stable and synthetic analog of EPOPROSTENOL, but with a longer half-life than the parent compound. Its actions are similar to prostacyclin. Iloprost produces vasodilation and inhibits platelet aggregation.
The volume of water filtered out of plasma through glomerular capillary walls into Bowman's capsules per unit of time. It is considered to be equivalent to INULIN clearance.
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
The blood pressure as recorded after wedging a CATHETER in a small PULMONARY ARTERY; believed to reflect the PRESSURE in the pulmonary CAPILLARIES.
Cell surface proteins that bind ENDOTHELINS with high affinity and trigger intracellular changes which influence the behavior of cells.
A class of drugs that act by selective inhibition of calcium influx through cellular membranes.
The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.
A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.
Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
A peptidyl-dipeptidase that catalyzes the release of a C-terminal dipeptide, -Xaa-*-Xbb-Xcc, when neither Xaa nor Xbb is Pro. It is a Cl(-)-dependent, zinc glycoprotein that is generally membrane-bound and active at neutral pH. It may also have endopeptidase activity on some substrates. (From Enzyme Nomenclature, 1992) EC
The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
Dilated blood vessels in the ESOPHAGUS or GASTRIC FUNDUS that shunt blood from the portal circulation (PORTAL SYSTEM) to the systemic venous circulation. Often they are observed in individuals with portal hypertension (HYPERTENSION, PORTAL).
Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.
The measurement of an organ in volume, mass, or heaviness.
The hemodynamic and electrophysiological action of the right HEART VENTRICLE.
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
Individuals whose ancestral origins are in the continent of Europe.
A series of heterocyclic compounds that are variously substituted in nature and are known also as purine bases. They include ADENINE and GUANINE, constituents of nucleic acids, as well as many alkaloids such as CAFFEINE and THEOPHYLLINE. Uric acid is the metabolic end product of purine metabolism.
Therapy with two or more separate preparations given for a combined effect.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
Compounds that specifically inhibit PHOSPHODIESTERASE 5.
A CALCIUM-dependent, constitutively-expressed form of nitric oxide synthase found primarily in ENDOTHELIAL CELLS.
Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.
A group of CORTICOSTEROIDS primarily associated with water and electrolyte balance. This is accomplished through the effect on ION TRANSPORT in renal tubules, resulting in retention of sodium and loss of potassium. Mineralocorticoid secretion is itself regulated by PLASMA VOLUME, serum potassium, and ANGIOTENSIN II.
The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.
A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
A condition in which the RIGHT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE or MYOCARDIAL INFARCTION, and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the right ventricular wall.
Sodium excretion by URINATION.
A subtype of endothelin receptor found predominantly in the VASCULAR SMOOTH MUSCLE. It has a high affinity for ENDOTHELIN-1 and ENDOTHELIN-2.
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
The blood pressure in the VEINS. It is usually measured to assess the filling PRESSURE to the HEART VENTRICLE.
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
An NADPH-dependent enzyme that catalyzes the conversion of L-ARGININE and OXYGEN to produce CITRULLINE and NITRIC OXIDE.
The venous pressure measured in the PORTAL VEIN.
A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS.
The number of males and females in a given population. The distribution may refer to how many men or women or what proportion of either in the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.
The relationship between the dose of an administered drug and the response of the organism to the drug.
The rhythmical expansion and contraction of an ARTERY produced by waves of pressure caused by the ejection of BLOOD from the left ventricle of the HEART as it contracts.
An angiotensin-converting enzyme inhibitor that is used to treat HYPERTENSION and HEART FAILURE.
An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
Hardening of the KIDNEY due to infiltration by fibrous connective tissue (FIBROSIS), usually caused by renovascular diseases or chronic HYPERTENSION. Nephrosclerosis leads to renal ISCHEMIA.
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Conditions with excess LIPIDS in the blood.
The lower right and left chambers of the heart. The right ventricle pumps venous BLOOD into the LUNGS and the left ventricle pumps oxygenated blood into the systemic arterial circulation.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
Pathological elevation of intra-abdominal pressure (>12 mm Hg). It may develop as a result of SEPSIS; PANCREATITIS; capillary leaks, burns, or surgery. When the pressure is higher than 20 mm Hg, often with end-organ dysfunction, it is referred to as abdominal compartment syndrome.
An alpha-2 adrenergic agonist that has both central and peripheral nervous system effects. Its primary clinical use is as an antihypertensive agent.
The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.
A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
The removal or interruption of some part of the sympathetic nervous system for therapeutic or research purposes.
Swelling of the OPTIC DISK, usually in association with increased intracranial pressure, characterized by hyperemia, blurring of the disk margins, microhemorrhages, blind spot enlargement, and engorgement of retinal veins. Chronic papilledema may cause OPTIC ATROPHY and visual loss. (Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p175)
Abnormalities in the serum levels of LIPIDS, including overproduction or deficiency. Abnormal serum lipid profiles may include high total CHOLESTEROL, high TRIGLYCERIDES, low HIGH DENSITY LIPOPROTEIN CHOLESTEROL, and elevated LOW DENSITY LIPOPROTEIN CHOLESTEROL.
The HEART and the BLOOD VESSELS by which BLOOD is pumped and circulated through the body.
A non-selective inhibitor of nitric oxide synthase. It has been used experimentally to induce hypertension.
A cluster of metabolic risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome X include excess ABDOMINAL FAT; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state. (from AHA/NHLBI/ADA Conference Proceedings, Circulation 2004; 109:551-556)
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
The frequency of different ages or age groups in a given population. The distribution may refer to either how many or what proportion of the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.
Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.
The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).
Inhaling and exhaling the smoke of burning TOBACCO.
The regular and simultaneous occurrence in a single interbreeding population of two or more discontinuous genotypes. The concept includes differences in genotypes ranging in size from a single nucleotide site (POLYMORPHISM, SINGLE NUCLEOTIDE) to large nucleotide sequences visible at a chromosomal level.
The flow of BLOOD through or around an organ or region of the body.
Typical way of life or manner of living characteristic of an individual or group. (From APA, Thesaurus of Psychological Index Terms, 8th ed)
A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.
General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
A powerful vasodilator used in emergencies to lower blood pressure or to improve cardiac function. It is also an indicator for free sulfhydryl groups in proteins.
A short thick vein formed by union of the superior mesenteric vein and the splenic vein.
21-Amino-acid peptides produced by vascular endothelial cells and functioning as potent vasoconstrictors. The endothelin family consists of three members, ENDOTHELIN-1; ENDOTHELIN-2; and ENDOTHELIN-3. All three peptides contain 21 amino acids, but vary in amino acid composition. The three peptides produce vasoconstrictor and pressor responses in various parts of the body. However, the quantitative profiles of the pharmacological activities are considerably different among the three isopeptides.
The smallest divisions of the arteries located between the muscular arteries and the capillaries.
A country spanning from central Asia to the Pacific Ocean.
Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.
Agents that antagonize ANGIOTENSIN RECEPTORS. Many drugs in this class specifically target the ANGIOTENSIN TYPE 1 RECEPTOR.
Persons living in the United States having origins in any of the black groups of Africa.
A group of compounds that contain the structure SO2NH2.
The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome.
A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products (Sies, Oxidative Stress, 1991, pxv-xvi).
A mitochondrial cytochrome P450 enzyme that catalyzes the 18-hydroxylation of steroids in the presence of molecular oxygen and NADPH-specific flavoprotein. This enzyme, encoded by CYP11B2 gene, is important in the conversion of CORTICOSTERONE to 18-hydroxycorticosterone and the subsequent conversion to ALDOSTERONE.
Distensibility measure of a chamber such as the lungs (LUNG COMPLIANCE) or bladder. Compliance is expressed as a change in volume per unit change in pressure.
Arteries which arise from the abdominal aorta and distribute to most of the intestines.
A potent natriuretic and vasodilatory peptide or mixture of different-sized low molecular weight PEPTIDES derived from a common precursor and secreted mainly by the HEART ATRIUM. All these peptides share a sequence of about 20 AMINO ACIDS.
Individuals whose ancestral origins are in the southeastern and eastern areas of the Asian continent.
Any of the tubular vessels conveying the blood (arteries, arterioles, capillaries, venules, and veins).

Effects of long-term administration of clonidine on plasma renin activity. (1/23689)

Plasma renin activity (PRA) was studied before and during long-term treatment with moderate oral doses (0.2 or 0.3 mg/d) of clonidine. Nine outpatients with essential hypertension received clonidine for 12 weeks; a significant decrease in blood pressure was evident in all patients. Except for a nonsignificant increase after 12 weeks of treatment, PRA values were not notably changed by clonidine therapy. No correlation was found between individual blood pressure changes and PRA variation during the study. The absence of a net effect on PRA in this study does not exclude more complex interactions of clonidine with the renin-angiotensin system. Nonetheless, clonidine cannot generally be classified as a "renin-inhibiting" drug.  (+info)

Phasic right coronary artery blood flow in conscious dogs with normal and elevated right ventricular pressures. (2/23689)

We studied phasic right coronary blood flow in well trained normal dogs and dogs with pulmonic stenosis. We installed electromagnetic flow transducers and pressure tubes under anesthesia to monitor right coronary blood flow, cardiac output, central aortic blood pressure, and right ventribular pressure. In normotensive dogs, systolic flow amplitude equaled early diastolic flow levels. The ratio of systolic to diastolic flow at rest was substantially greater in the right coronary bed (36+/-1.3%) than in the left circumflex bed (13+/-3.6%). Right diastolid flow runoff, including the cove late in diastole, resembled left circumflex runoff. Blood flow to the normotensive right (37+/-1.1 ml/min 100(-1) g) and the left (35+/-1.0 ml/min(-1) g) ventricular myocardium indicated equal perfusion of both cardiac walls. Throttling of systolic flow was related directly to the right ventricular systolic pressure level in the dogs with pulmonic stenosis. Retrograde systolic flow occurred in severe right ventricular hypertension. The late diastolic runoff pattern in dogs with pulmonic stenosis appeared the same as for the normotensive dogs. We obtained systolic to diastolic flow ratios of 1/3 the value of normotensive hearts in high and severe pulmonic hypertension. Electrocardiograms and studies of pathology suggested restricted blood flow to the inner layers of the right myocardium in the dogs with severe and high right ventricular hypertension. Normotensive and hypertensive peak hyperemic flow responses were similar, except for an increased magnitude of diastolic flow, with proportionately less systolic flow in hypertensive states.  (+info)

Quantification of baroreceptor influence on arterial pressure changes seen in primary angiotension-induced hypertension in dogs. (3/23689)

We studied the role of the sino-aortic baroreceptors in the gradual development of hypertension induced by prolonged administration of small amounts of angiotensin II (A II) in intact dogs and dogs with denervated sino-aortic baroreceptors. Short-term 1-hour infusions of A II(1.0-100 ng/kg per min) showed that conscious denervated dogs had twice the pressor sensitivity of intact dogs. Long-term infusions of A II at 5.0 ng/kg per min (2-3 weeks) with continuous 24-hour recordings of arterial pressure showed that intact dogs required 28 hours to reach the same level of pressure attained by denervated dogs during the 1st hour of infusion. At the 28th hour the pressure in both groups was 70% of the maximum value attained by the 7th day of infusion. Both intact and denervated dogs reached nearly the same plateau level of pressure, the magnitude being directly related both the the A II infusion rate and the daily sodium intake. Cardiac output in intact dogs initially decreased after the onset of A II infusion, but by the 5th day of infusion it was 38% above control, whereas blood volume was unchanged. Heart rate returned to normal after a reduction during the 1st day of infusion in intact dogs. Plasma renin activity could not be detected after 24 hours of A II infusion in either intact or denervated dogs. The data indicate that about 35% of the hypertensive effect of A II results from its acute pressor action, and an additional 35% of the gradual increase in arterial pressure is in large measure a result of baroreceptor resetting. We conclude that the final 30% increase in pressure seems to result from increased cardiac output, the cause of which may be decreased vascular compliance. since the blood volume remains unaltered.  (+info)

Acute and chronic dose-response relationships for angiotensin, aldosterone, and arterial pressure at varying levels of sodium intake. (4/23689)

We examined the acute and chronic dose-response relationships between intravenously infused angiotensin II (A II) and the resulting changes in arterial pressure and plasma aldosterone concentration at varying levels of sodium intake. Sequential analysis of plasma aldosterone at each A II infusion rate resulted in an acute dose-related increase in plasma aldosterone which was markedly attenuated after the first 24 hours of infusion, the final level being directly related to the dose of A II and inversely related to sodium intake. A II infused at 5,15, and 23 ng/kg per min was associated with an initial increase (2nd to 8th hour) in plasma aldosterone to 2,6, and 9 times control values, respectively, in dogs receiving 40 mEq Na+/day. But, after the 1st day, aldosterone averaged only 1, 1.7, and 3 times control values for the next 2 weeks at the same rates of A II infusion. Dogs receiving 120 mEq Na+/day during A II infusion exhibited only a transient increase in plasma aldosterone during the 1st day. Sustained hypertension developed over a period of a week at all doses of A II at normal and high sodium intake, but did not occur at any dose of A II in sodium-depleted dogs. Increasing sodium intake from 40 to 120 mEq/day resulted in higher levels of hypertension, 125% compared to 140% of ocntrol values for dogs infused with A II, 5.0 ng/kg per min. We conclude that primary angiotensin-induced hypertension need not be associated with increased levels of plasma aldosterone, which appears to remain elevated only with amounts of A II greater than those required to sustain a significant degree of hypertension.  (+info)

Dietary intake and practices in the Hong Kong Chinese population. (5/23689)

OBJECTIVES: To examine dietary intake and practices of the adult Hong Kong Chinese population to provide a basis for future public health recommendations with regard to prevention of certain chronic diseases such as cardiovascular disease, hypertension, and osteoporosis. PARTICIPANTS: Age and sex stratified random sample of the Hong Kong Chinese population aged 25 to 74 years (500 men, 510 women). METHOD: A food frequency method over a one week period was used for nutrient quantification, and a separate questionnaire was used for assessment of dietary habits. Information was obtained by interview. RESULTS: Men had higher intakes of energy and higher nutrient density of vitamin D, monounsaturated fatty acids and cholesterol, but lower nutrient density of protein, many vitamins, calcium, iron, copper, and polyunsaturated fatty acids. There was an age related decrease in energy intake and other nutrients except for vitamin C, sodium, potassium, and percentage of total calorie from carbohydrate, which all increased with age. Approximately 50% of the population had a cholesterol intake of < or = 300 mg; 60% had a fat intake < or = 30% of total energy; and 85% had a percentage of energy from saturated fats < or = 10%; criteria considered desirable for cardiovascular health. Seventy eight per cent of the population had sodium intake values in the range shown to be associated with the age related rise in blood pressure with age. Mean calcium intake was lower than the FAO/WHO recommendations. The awareness of the value of wholemeal bread and polyunsaturated fat spreads was lower in this population compared with that in Australia. There was a marked difference in types of cooking oil compared with Singaporeans, the latter using more coconut/palm/mixed vegetable oils. CONCLUSION: Although the current intake pattern for cardiovascular health for fat, saturated fatty acid, and cholesterol fall within the recommended range for over 50% of the population, follow up surveys to monitor the pattern would be needed. Decreasing salt consumption, increasing calcium intake, and increasing the awareness of the health value of fibre may all be beneficial in the context of chronic disease prevention.  (+info)

Low calorie diet enhances renal, hemodynamic, and humoral effects of exogenous atrial natriuretic peptide in obese hypertensives. (6/23689)

The expression of the natriuretic peptide clearance receptor is abundant in human and rat adipose tissue, where it is specifically inhibited by fasting. In obese hypertensives, plasma atrial natriuretic peptide (ANP) levels were found to be lower than in obese normotensives. Therefore, the increased adipose mass might influence ANP levels and/or its biological activity. The aim of the present study was to evaluate whether the humoral, hemodynamic, and renal effects of exogenous ANP in obese hypertensives might be enhanced by a very low calorie diet. Eight obese hypertensives received a bolus injection of ANP (0.6 mg/kg) after 2 weeks of a normal calorie/normal sodium diet, and blood pressure (BP), heart rate, ANP, cGMP, plasma renin activity, and aldosterone were evaluated for 2 hours before and after the injection. Diuresis and natriuresis were measured every 30 minutes. The patients then started a low calorie/normal sodium diet (510 kcal/150 mmol/d) for 4 days, and then the ANP injection protocol was repeated. The low calorie diet induced a slight weight loss (from 90.6+/-1.1 to 87. 7+/-1.2 kg; P<0.01), which was accompanied by increase of cGMP excretion (from 146.0+/-10.1 to 154.5+/-9.5 nmol/24 h; P<0.05) together with a reduction of BP (P<0.01 versus basal levels). ANP injection after diet was followed by an increase of ANP levels similar to that observed before diet, but plasma cGMP, diuresis, and natriuresis increased significantly only after diet. Similarly, the decrease of BP after ANP administration was significantly higher after diet (change in mean arterial pressure, -6.4+/-0.7 versus -4. 0+/-0.6 mm Hg; P<0.05) as well as that of aldosterone (P<0.01). These data show that a low calorie diet enhances the humoral, renal, and hemodynamic effects of ANP in obese hypertensives and confirm the importance of caloric intake in modulating the biological activity of ANP, suggesting that the natriuretic peptide system can play a role in the acute changes of natriuresis and diuresis associated with caloric restriction.  (+info)

Myocardial osteopontin expression coincides with the development of heart failure. (7/23689)

To identify genes that are differentially expressed during the transition from compensated hypertrophy to failure, myocardial mRNA from spontaneously hypertensive rats (SHR) with heart failure (SHR-F) was compared with that from age-matched SHR with compensated hypertrophy (SHR-NF) and normotensive Wistar-Kyoto rats (WKY) by differential display reverse transcriptase-polymerase chain reaction. Characterization of a transcript differentially expressed in SHR-F yielded a cDNA with homology to the extracellular matrix protein osteopontin. Northern analysis showed low levels of osteopontin mRNA in left ventricular myocardium from WKY and SHR-NF but a markedly increased (approximately 10-fold) level in SHR-F. In myocardium from WKY and SHR-NF, in situ hybridization showed only scant osteopontin mRNA, primarily in arteriolar cells. In SHR-F, in situ hybridization revealed abundant expression of osteopontin mRNA, primarily in nonmyocytes in the interstitial and perivascular space. Similar findings for osteopontin protein were observed in the midwall region of myocardium from the SHR-F group. Consistent with the findings in SHR, osteopontin mRNA was minimally increased (approximately 1.9-fold) in left ventricular myocardium from nonfailing aortic-banded rats with pressure-overload hypertrophy but was markedly increased (approximately 8-fold) in banded rats with failure. Treatment with captopril starting before or after the onset of failure in the SHR reduced the increase in left ventricular osteopontin mRNA levels. Thus, osteopontin expression is markedly increased in the heart coincident with the development of heart failure. The source of osteopontin in SHR-F is primarily nonmyocytes, and its induction is inhibited by an angiotensin-converting enzyme inhibitor, suggesting a role for angiotensin II. Given the known biological activities of osteopontin, including cell adhesion and regulation of inducible nitric oxide synthase gene expression, these data suggest that it could play a role in the pathophysiology of heart failure.  (+info)

Gender-related differences in myocyte remodeling in progression to heart failure. (8/23689)

Gender-related differences responsible for the better prognosis of females with heart failure have not been clearly established. To address this issue, we investigated potential gender-related differences in myocyte remodeling in spontaneously hypertensive heart failure rats. Echocardiograms and myocyte growth were compared between males and females at compensated (2, 4, and 6 months) and decompensated (18 months in males and 24 months in females) stages of cardiac hypertrophy. Although left ventricular diastolic dimensions did not differ significantly between failing male and female rats, fractional shortening declined significantly only in failing males. Myocyte cross-sectional area did not change after 4 months of age in both genders, which is likely to be responsible for the absence of a change in left ventricular wall thickness during the progression to heart failure. Myocyte volume and cross-sectional area were significantly larger in males than females at 2, 4, and 6 months of age, although there were no significant differences at the failing stage. Reduced adaptive hypertrophic reserve was observed in males, which is likely to contribute to the higher morbidity and mortality of males with chronic heart failure.  (+info)

Background: Subclinical target organ damage (TOD) has been common in hypertensive children, but there is limited data in the Chinese pediatric population. This study aimed to investigate the prevalence of subclinical TOD in the Chinese hypertensive children and adolescents.Methods: A cross-sectional study was performed in children and adolescents from four schools in Jinan, China between September 2012 and September 2014. The hypertensive status was confirmed based on elevated blood pressure across three different occasions. Those with hypertension were invited to participate in the evaluation of TOD (including heart, arteries, and kidney) and metabolic disorders. A total of 7,840 children and adolescents aged 6-17 years were recruited at baseline, of whom 373 were diagnosed as hypertensive after three separate visits, and 333 (89%) participated in evaluation of TOD.Results: Among 333 hypertensive children, 47.4% had elevated carotid intima-media thickness, 32.4% had left ventricular hypertrophy, 29.2%
The kidneys are of the main organs that intervene in blood pressure control and most of kidney diseases can lead to high blood pressure. Uncontrolled hypertension will undoubted lead to chronic kidney disease progression.. With the addition of Dr. Fidel Barrantes, board certified hypertension specialist, Renal Medicine Associates has started a hypertension clinic to focus on care of patients who have difficult to control hypertension (patients who are in 3 medications without achieving adequate blood pressure control), white-coat hypertension, masked-hypertension, poorly controlled hypertension, stress-related hypertension, all secondary and hormonal causes of hypertension, and hypertension complicating pregnancy.. Our hypertension clinic focus is to provide a multidisciplinary approach. Our Hypertension clinic is currently receiving new patients.. ...
Psychosomatic factors, sympathoneural and sympathoadrenal as well as cardiovascular mechanisms, were studied in 24 patients 18-24 years of age with borderline hypertension, 50 age-matched normotensive offspring of hypertensive parents, and 49 controls with no family history of hypertension. They were compared by projective and questionnaire-based psychological tests and their circulatory and neurohormonal reactivity to mental (Stroop color-word conflict test and arithmetic test) and physical stressors (orthostasis and bicycle ergometry test) were measured. Borderline hypertensive subjects externalized aggression less (p less than 0.05) but internalized it more (p less than 0.05) and were more submissive (p less than 0.05) when compared with controls. Offspring of hypertensive parents showed a similar but weaker pattern. Both risk groups reported more positive interactions with their parents (genetic risk subjects versus controls, p less than 0.05; borderline hypertensive patients versus ...
The present study examined plasma lipoprotein, lipoprotein lipase, hepatic lipase, and insulin levels in men with borderline hypertension (diastolic blood pressure 85 to 94 mm Hg) compared with age-matched normotensive control subjects (diastolic blood pressure less than or equal to 80 mm Hg, n = 75 + 75). High-density lipoprotein (HDL) subclasses were determined in a subset (n = 45 + 45). While total and low-density lipoprotein cholesterol levels were similar, levels of very-low-density lipoprotein (VLDL) cholesterol and triglycerides (0.46 versus 0.41 mmol/L, P = .027, and 1.0 versus 0.85 mmol/L, P = .031) and total triglycerides (1.53 versus 1.33 mmol/L, P = .009) were elevated and HDL cholesterol was reduced in the borderline group compared with the normotensive group (1.17 versus 1.26 mmol/L, P = .043). The HDL subclass HDL2b concentration was lower (0.16 versus 0.24 mmol/L, P = .006), while HDL3b and HDL3c concentrations were higher in the borderline group (0.38 versus 0.32 mmol/L, P = ...
Hypertension is a major global public health problem due to its related high morbidity and mortality especially in developing countries, with a prevalence of 46% in the adult population. The study was aimed at investigating the prevalence of metabolic syndrome among hypertensive outpatients and its associated effect on target organs. Questionnaire was administered to 150 hypertensive outpatients and 50 non-hypertensives. Anthropometrics such as body mass index, waist circumference, body fat, visceral fat, blood pressure and biochemical parameters including lipid profile, urea, AST, ALT, and coronary risk were determined using standard procedures. Dietary pattern of hypertensives was not different from non-hypertensives. Metabolic syndrome was found to be significantly prevalent among hypertensive group than non-hypertensive group. Among cardiovascular disease markers, high coronary disease risk was significantly higher among participants with metabolic syndrome compared to those without ...
According to recent studies about 1 in 3 American adults have high blood pressure. But unfortunately as they rarely show any symptoms about 1/3 of these do not even know that they have it. So where will people like this go to get information on high blood pressure to understand the condition better and find methods to regulate blood pressure levels?. High blood pressure has become known as the silent killer. Many people do not show any symptoms until the condition has reached a much later stage of development.. In fact the only real way a person can ever tell if they have high blood pressure is by getting a blood pressure reading, generally from a doctor or health professional. Normally, if a docto fashion jackets r thinks that a patient may have high blood pressure then they may ask them to return to the surgery potentially a few times to have the reading checked again. This is so that an accurate baseline can be established. There are a number of factors that can temporarily increase blood ...
This study investigated the effect of proximity to city parks on blood pressure categories during the first trimester of pregnancy. This cross-sectional study included 3,416 female residents of the city of Kaunas, Lithuania, who were enrolled in the FP7 PHENOTYPE project study. The women were classified into four blood pressure categories: optimal, normal, high-normal blood pressure, and hypertension. Multinomial regression models were used to investigate the association between three womens groups with respect to the residence distances from city parks (300, , 300-1,000, and , 1,000 m) and four blood pressure categories. When using the optimal blood pressure as the reference group, the crude and adjusted odds ratios (OR) for normal blood pressure and for high-normal blood pressure proved to be statistically significantly higher after the inclusion of the selected covariates into the regression analysis. The probability of normal blood pressure increased by 9%, and that of high-normal blood ...
Hypertension is a chapter in the book, Cardiovascular Medicine, containing the following 19 pages: Hypertension, Isolated Systolic Hypertension, Hypertension Causes, Hypertension Criteria, Hypertension Evaluation, Hypertension Evaluation Exam, Hypertension Evaluation History, Hypertension Evaluation Labs, Hypertension Management, Hypertension Risk Stratification, Antihypertensive Selection, Resistant Hypertension, Hypertension Management for Specific Comorbid Diseases, Hypertension Management for Specific Populations, Hypertension Management for Specific Emergencies, Hypertension Resources, Pseudohypertension, Hypertensive Encephalopathy, Severe Asymptomatic Hypertension.
PURPOSE OF REVIEW In a society with a steadily increasing population of patients with hypertension, a significant mortality risk factor, it is important that clinicians be cognizant of the changes seen in ophthalmic examination. This paper demonstrates both the acute and chronic stages of the disease. RECENT FINDINGS This paper first presents the history of classifying different stages of hypertensive retinopathy, a condition associated with systemic arterial hypertension, as defined by Keith-Wagener-Barker. The most recent recommendations published in the Seventh Report of the Joint National Committee (JNC) on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure are also described; this report defines the current status and classification of hypertension in the United States, as well as recommendations for its treatment and management. Finally, disease management strategies and currently accepted treatment options are presented. SUMMARY Since systemic arterial hypertension is a
Despite the impressive increase of home blood pressure monitoring (BPM) among hypertensive patients over the last few years, a limited number of studies have analysed the rate of home BPM and its relationship with target blood pressure (BP) control, in representative samples of the hypertensive population. The objectives of the study were first to evaluate the prevalence of home BPM in a large selected group of treated hypertensive patients referred to our outpatient hypertension hospital clinic. Second, to assess the rate of satisfactory clinic BP control in patients with or without familiarity with home BPM. In all, 1350 consecutive hypertensive patients who attended our hypertension centre during a period of 12 months and were regularly followed up by the same medical team were included in the study. After informed consent all patients underwent the following procedures: (1) accurate medical history (implemented by a structured questionnaire on demographic and clinical characteristics, ...
Essential hypertension (also called primary hypertension or idiopathic hypertension) is the form of hypertension that by definition has no identifiable cause. It is the most common type of hypertension, affecting 95% of hypertensive patients, it tends to be familial and is likely to be the consequence of an interaction between environmental and genetic factors. Prevalence of essential hypertension increases with age, and individuals with relatively high blood pressure at younger ages are at increased risk for the subsequent development of hypertension. Hypertension can increase the risk of cerebral, cardiac, and renal events. A recent classification recommends blood pressure criteria for defining normal blood pressure, prehypertension, hypertension (stages I and II), and isolated systolic hypertension, which is a common occurrence among the elderly. These readings are based on the average of seated blood pressure readings that were properly measured during 2 or more office visits. In individuals ...
View Notes - HYPERTENSION_SEVERE from PNR 182 at Orangeburg-Calhoun Technical College. HYPERTENSION: SEVERE Hypertension is defined by the 1992 Joint National Committee on Detection, Evaluation, and
High Blood Pressure, Hypertension Treatment of Alternative High Blood Pressure Alternative Neuro Acupuncture Treatment and High Blood Pressure Herbal Herbs Alternative Medicine Treatment on High Blood Pressure Treatment Medical Center High Blood Pressure Remedies
Primary hypertension is not just an adult disorder. Current US population data on children and adolescents demonstrate a prevalence of elevated blood pressure (BP) and hypertension combined of over 10%. Recent reports from prospective cohort studies describe an association of high BP in childhood with hypertension in young adulthood. Excess adiposity is strongly associated with higher BP in childhood and increases risk for hypertension in adulthood. In addition to overweight/obesity, other exposures that raise the risk for high BP include low birthweight, dietary sodium, and stress. Using intermediate markers of cardiovascular injury, studies on hypertensive children report findings of cardiac hypertrophy, vascular stiffness, and early atherosclerotic changes. Impaired cognitive function has also been demonstrated in hypertensive children. Recent advances in clinical and translational research support the concept that the evolution of primary hypertension begins in childhood.
It helped so much that he had to go to the doctor to have his blood pressure meds lowered in order to be more in line with the benefits of the CBD oil. CBD oil can help with so many ailments from anxiety and depression to lowering blood sugar and blood pressure. The science of CBD oil for blood pressure control is compelling, but a word of warning is required. For anyone already taking blood pressure medications, its inadvisable to take CBD alongside these medicines without speaking to a doctor first. Using CBD Oil to Reduce Blood Pressure to Normal. All the studies seem to agree that CBD reduces high blood pressure. The product, CBD oil, is, therefore, a more natural remedy for people with cardiovascular related problems which sometimes lead to death. Remember: hypertension affects one in every three adults. CBD Effects on Blood Pressure, and Hypertension. Many people use the terms hypertension and high blood pressure synonymously. This happens so frequently that many believe that they ...
1. To investigate whether reduced activity of pressor systems could explain the spontaneous drop in pressure upon hospitalization, 51 subjects with uncomplicated essential hypertension were admitted to hospital. Sodium intake was fixed at 55 mmol/day.. 2. Blood samples for noradrenaline, adrenaline, active renin, angiotensin II and aldosterone were drawn on each morning of the first 3 days of hospitalization; blood pressure was measured at 2 h intervals and values were averaged for each day.. 3. Subjects were divided in two groups depending on whether they became normotensive (group 1; n = 12) or remained hypertensive (group 2; n = 39). This distinction was thought to reflect mild and more severe hypertensive groups respectively.. 4. Although both groups showed a comparable fall in blood pressure during hospitalization, noradrenaline levels fell more consistently in group 1, whereas adrenaline levels fell only in group 2. The components of the renin-angiotensin-aldosterone system rose, but more ...
Background: Hypertension potentiates cardiovascular risk in survivors of childhood cancer previously exposed to cardiotoxic therapies, so it is important to determine the prevalence and risk factors for hypertensive blood pressure in this high-risk group.. Methods: Participants included 3,016 adult 10-year survivors of childhood cancer who had resting blood pressure measurements performed at St. Jude Childrens Research Hospital (Memphis, TN). We characterized the blood pressure status of participants, calculated standardized prevalence ratios based on U.S. population rates, and examined demographic and treatment factors associated with hypertensive blood pressure using logistic regression.. Results: The age-specific cumulative prevalence of hypertension in survivors increased sharply with age, exceeding 70% by age 50, and was substantially higher in all diagnosis groups than expected on the basis of age-, sex-, race/ethnicity-, and BMI-specific population rates. Specific cancer treatments were ...
1. Franklin SS, Jacobs MJ, Wong ND et al. Predominance of isolated systolic hypertension among middle-aged and elderly US hypertensives: analysis based on National Health and Nutrition Examination Survey (NHANES) III. Hypertension 2001; 37(3): 869-874. 2. Chobanian AV, Bakris GL, Black HR et al. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 Report. JAMA 2003; 289(19): 2560-2572. 3. Hsu CY, McCulloch CE, Darbinian J et al. Elevated blood pressure and risk of end-stage renal disease in subjects without baseline kidney disease. Arch Intern Med 2005; 165(8): 923-928. 4. Sundström J, Arima H, Jackson R et al. Effects of blood pressure reduction in mild hypertension: a systematic review and meta-analysis. Ann Intern Med 2015; 162(3): 184-191. 5. Neal B, MacMahon S, Chapman N et al. Effects of ACE inhibitors, calcium antagonists, and other blood - pressure - lowering drugs: results of prospectively designed ...
Computerized Clinical Records, which are incorporated in primary health care practice, have great potential for research. In order to use this information, data quality and reliability must be assessed to prevent compromising the validity of the results. The aim of this study is to validate the diagnosis of hypertension and diabetes mellitus in the computerized clinical records of primary health care, taking the diagnosis criteria established in the most prominently used clinical guidelines as the gold standard against which what measure the sensitivity, specificity, and determine the predictive values. The gold standard for diabetes mellitus was the diagnostic criteria established in 2003 American Diabetes Association Consensus Statement for diabetic subjects. The gold standard for hypertension was the diagnostic criteria established in the Joint National Committee published in 2003. A cross-sectional multicentre validation study of diabetes mellitus and hypertension diagnoses in computerized clinical
Hypertension is the medical term for high blood pressure. A normal blood pressure is 120/80. A blood pressure reading higher or equal to 140/90 is considered abnormally high. Elevated blood pressure means your heart is working harder than normal, putting both your heart and arteries under great strain. High blood pressure is serious business. On average, people with uncontrolled hypertension are:Seven times more likely to have a stroke. Six times more likely to develop congestive heart failure. Three times more likely to have a heart attack.Different types of hypertensionFrom my research, I didnt find any other types of hypertension.What are some causes?In 90% of cases, the cause of hypertension is unknown. This is called essential hypertension. The other 10% of cases is called secondary hypertension. Secondary hypertension is caused by kidney disease, severe narrowing of the aorta, tumors in the adrenal gland, or hardening of the arteries. There are many factors associated with high blood ...
Diagnosis of resistant hypertension: In case of clinic blood pressure exceeding the boundary of systolic blood pressure at 140mmHg and diastolic blood pressure at 90mmHg (hereinafter refer to as 140/90mmHg) (130/80mmHg for patients with diabetes mellitus or chronic renal disease) despite triple antihypertensive therapy at optimal dose may be diagnosed as resistant hypertension. Antihypertensive medications used include diuretics. Resistant hypertension may also be diagnosed when clinic blood pressure has reached the target value but quadruple or more of antihypertensives are used ...
About hypertension. Hypertension is a chronic medical condition in which blood pressure in the arteries is elevated. Blood pressure is expressed by two measurements, systolic and diastolic pressures, which are the maximum and minimum pressures, respectively, in the arterial system. Normal blood pressure at rest is within the range of 100-140 mmHg systolic and 60-90 mmHg diastolic. Hypertension is present if the blood pressure is persistently at or above 140/90 mmHg for adults. Sustained hypertension over time is a major risk factor for heart disease, coronary artery disease, stroke, aortic aneurysm, peripheral artery disease and chronic kidney disease. Hypertension affects over 1 billion people worldwide.. About renal denervation. Renal denervation is an interventional approach for the treatment of high blood pressure. A minimally-invasive, endovascular-catheter-based procedure, it uses radiofrequency or ultrasound ablation to treat resistant hypertension. Nerves in the wall of the renal artery ...
The occurrence of the C3F allele was investigated in the following three groups: 69 consecutive referred patients with untreated essential hypertension, including borderline hypertension; 70 patients with established and treated essential hypertension, already attending the same outpatient clinic, and 62 age- and sex-matched normotensive healthy subjects without clinical signs of atherosclerosis or familial predisposition to hypertension. In the three groups the C3F allele was found in 38.2%, 29% and 20%, respectively. Among the treated hypertensive patients with C3F gene, 40% had coronary heart disease (CHD) compared to 6.1% among the C3F negative (P less than 0.005), and the relative risk of CHD among the treated hypertensive patients with this allele was found to be 10.2 (P less than 0.002). The C3F gene was present in 72.7% of the treated patients with CHD. In the untreated patients the occurrence of CHD was low, and no differences between C3F positive and negative patients could be ...
Survey data show that awareness, treatment, and control of hypertension have increased dramatically since 1974. In 1974, only 51% of hypertensive persons were aware that their blood pressure was high. Thirty-six percent of these persons were under treatment, and 16% of those being treated had their blood pressure under control (160 mm Hg systolic or 95 mm Hg diastolic). By 1984, 85% were aware of their condition, and 74% were under treatment (1). In 1984, however, the definition of high blood pressure was changed from 160/95 mm Hg to 140/90 mm Hg. Because of this new definition, surveys conducted during 1982-1984 showed that only 24% of hypertensive patients on medication had their blood pressure under control (2). Because most hypertensive persons have been told that their blood pressure is high, surveys using self-reported blood pressure status have been used to assess awareness, treatment, and perceived control of high blood pressure (3). The Behavioral Risk Factor Surveillance System (BRFSS) ...
There is no cure for primary hypertension, but blood pressure can almost always be lower with the correct treatment. The goal of treatment is to lower blood pressure to levels that will prevent heart disease and other complications of hypertension. In secondary hypertension, the disease that is responsible for the hypertension is treated in addition to the hypertension itself.Successful treatment of the underlying disorders may cure the secondary hypertension. Treatment to lower blood pressure may include changes in diet, getting regular exercise,and taking antihypertensive medications. Patients falling into the pre-hypertension range who dont have damage to the heart or kidneys often are advised to make needed lifestyle changes only.Eat more fruit and vegetables ...
1. Chobanian AV, Bakris GL, Black HR et al (for the National High Blood Pressure Education Program Coordinating Committee). Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension 2003; 42(6): 1206-1252. 2. Mancia G, De BG, Dominiczak A, Cifkova R et al. 2007 Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens 2007; 25(6): 1105-1187. 3. Mancia G, Laurent S, Agabiti-Rosei E et al. Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document. J Hypertens 2009; 27(11): 2121-2158. 4. Oh BH, Mitchell J, Herron JR et al. Aliskiren, an oral renin inhibitor, provides dose-dependent efficacy and sustained 24-hour blood pressure control in patients with hypertension. J Am Coll Cardiol. 2007; 49(11): ...
On One Hand: Chronic Hypertension Can Affect PregnancyWhen a woman has high blood pressure before becoming pregnant, it is referred to as chronic hypertension. According to the National Heart, Lung, and Blood Institute, expectant mothers with chronic hypertension are more likely to experience complications, such as low birth weight, preterm delivery and preeclampsia. However, carefully monitoring chronic hypertension can prevent serious problems from occurring during pregnancy.On the Other: Gestational Hypertension Is More SeriousGestational hypertension (also called pregnancy induced hypertension, toxemia or preeclampsia) is a condition t...
TY - JOUR. T1 - Age-race subgroup compared with renin profile as predictors of blood pressure response to antihypertensive therapy. AU - Preston, Richard A.. AU - Materson, Barry J.. AU - Reda, Domenic J.. AU - Williams, David W.. AU - Hamburger, Robert J.. AU - Cushman, William C.. AU - Anderson, Robert J.. PY - 1998/10/7. Y1 - 1998/10/7. N2 - Context. - Renin profiling and age-race subgroup may help select single- drug therapy for stage 1 and stage 2 hypertension. Objective. - To compare the plasma renin profiling and age-race subgroup methods as predictors of response to single-drug therapy in men with stage 1 and 2 hypertension as defined by the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure. Design. - The Veterans Affairs Cooperative on Single-Drug Therapy of Hypertension, a randomized controlled trial. Setting. - Fifteen Veterans Affairs hypertension centers. Patients. - A total of 1105 ambulatory men with entry diastolic blood pressure ...
Obesity is a major public health issue, and hypertension is one of the most common associated comorbidities. Current guidelines for optimal blood pressure levels in obese patients or for the treatment of obesity-hypertension do not provide specific recommendations that go beyond the rather general recommendation to lose weight. Based on the strong ties between obesity, hypertension, and type 2 diabetes, and the similarity of complications that occur in obesity-related hypertension and in hypertension associated with type 2 diabetes, it seems appropriate to explore the optimal blood pressure levels for obese hypertensive patients. Recently published studies underline the importance of weight reduction to reach this goal. Several lines of reasoning support the use of angiotensin converting enzyme inhibitors or angiotensin receptor blockers as the appropriate first-line therapy in obese patients with uncomplicated hypertension. Nondihydropyridine calcium channel blockers, {alpha}-blockers, or ...
The World Health Organization has identified hypertension, or high blood pressure, as the leading cause of cardiovascular mortality.[162] The World Hypertension League (WHL), an umbrella organization of 85 national hypertension societies and leagues, recognized that more than 50% of the hypertensive population worldwide are unaware of their condition.[162] To address this problem, the WHL initiated a global awareness campaign on hypertension in 2005 and dedicated May 17 of each year as World Hypertension Day (WHD). Over the past three years, more national societies have been engaging in WHD and have been innovative in their activities to get the message to the public. In 2007, there was record participation from 47 member countries of the WHL. During the week of WHD, all these countries - in partnership with their local governments, professional societies, nongovernmental organizations and private industries - promoted hypertension awareness among the public through several media and public ...
#High Blood Pressure#Hypertension#Proper Diet - Hypertension, or high blood pressure, is a condition where the pressure of blood against the walls of vessels is persistently elevated. A blood pressure close to 120/90 is considered normal and is considered high when it crosses 140/90. There are millions of cases of hypertension reported every year and it can last for years or can even be life-long. What makes hypertension a serious condition is that it often has no symptoms, and if left untreated over a long period of time, it may lead to serious health conditions like heart disease and strokes. Hypertension patients have to take special care of their daily meals and follow a strict high blood pressure diet to manage symptoms of the condition. This season demands that BP patients include healthy summer drinks in their diet. Adding certain foods and drinks to your daily diet may help regulate symptoms of hypertension. Ideally, high blood pressure patients should eat foods that are low in sodium and
Essential hypertension diagnosis (costs for program #105475) ✔ University Hospital RWTH Aachen ✔ Department of Cardiology, Pneumology, Angiology and Internal Intensive Medicine ✔
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Controlling High Blood Pressure is very crucial, especially when you are aging. Hypertension is a condition which should be prevented because it can be the reason for your frequent illness. According to a Harvard University Research, more than 15% of Americans die because of hypertension and related health problems. It shows no indications, but hypertension increases the risks of killer disease like kidney failure, cognitive decline, heart attack, etc. American Heart Association (A.H.A) research says, more than 25% of the US population has hypertension, but they arent aware of it. In case you didnt have yourself checked up in the last 2 years, do it at the earliest.. You can get relief from High Blood pressure, if you take medicines. But even the medicines have side effects like sleep disorders, Leg Cramps, etc. But usually people are able to bring down the High Blood Pressure without taking any medicines.. Below are the some tips to lower your high blood pressure. 1. Start Power ...
randomised controlled trials (RCTs) that compared interventions aimed at improving BP with no intervention or usual care in patients with treated or untreated essential hypertension and assessed mean systolic (SBP) or diastolic BP (DBP), control of BP, or proportion of patients followed up at clinic. Studies of interventions not intended to increase BP control by organisational or educational means (eg, drug trials) were … ...
The majority of hypertensive patients are overweight or obese [1]. The issue is clinically relevant for several reasons. First, obesity and arterial hypertension can be additive in terms of cardiovascular and metabolic risk. For example, obesity and arterial hypertension predispose a person to left ventricular hypertrophy. The risk is increased further in patients burdened by both risk factors. Second, obesity can cause or exacerbate arterial hypertension. In the third National Health and Nutrition Examination Survey hypertension risk was increased in overweight and more so in obese individuals [2]. Third, blood pressure control is more difficult to achieve, and treatment-resistant arterial hypertension is an important problem in obese patients. The latter topic has been the focus of a recent joint scientific statement by the European Society of Hypertension and the European Association for the Study of Obesity in this Journal [3]. Indeed, the average BMI in the recently published controlled ...
Obesity and hypertension are closely associated. Hypertension occurs frequently in industrialized populations that gain weight with advancing age, and is infrequent in primitive populations that are not obese. There are two reasons for concern about the relationship of obesity to hypertension. Weight gain in young adult life is a potent risk factor for later development of hypertension. Weight reduction in obese hypertensive persons often reduces arterial pressure. Mechanisms of obesity hypertension are as yet unidentified; an earlier hypothesis that it is related to salt intake has not been supported by recent studies. Hemodynamic studies have shown that obesity is associated with an elevated cardiac output and expanded blood volume; in normotensive obese persons peripheral vascular resistance is reduced, and in hypertensive persons it is normal or elevated. Studies of hormonal and neural factors have failed to explain the presence of hypertension in some obese persons and its absence in others. ...
The overall purpose of hypertension treatment is 2-fold. First, patients often have symptoms that are related to their high blood pressure and although subtle in many instances may be improved dramatically by blood pressure control. The main reason for blood pressure treatment, however, is to reduce the burden of cardiovascular complications and end organ damage related to the condition. This may be considered the ultimate goal of blood pressure treatment. In this respect, actual blood pressure measurements may be seen as surrogate end points as the organ protective effects of two antihypertensive agents may differ significantly even though their blood pressure lowering effects are similar. Thus beta-blockers, once seen as first-line treatment of hypertension for most patients, now are considered as third- or fourthline agents according to the latest NICE guidelines (National Institute for Health and Clinical Excellence, On the other hand, agents that inhibit the activity ...
RESULTS Forty-three (52%) subjects were hypertensive, and 30 subjects were classified as having nocturnal hypertension. cIMT was higher in the nocturnal hypertensive group than in the normotensive group (0.44 ± 0.03 vs. 0.42 ± 0.04 mm, P = 0.026). Among children and adolescents with nonhypertensive blood pressure levels in clinic blood pressure monitoring, cIMT and daytime blood pressure were higher in the nocturnal hypertensive group. All ABPM parameters were significantly related to cIMT in multiple linear regression analysis. ...
Prazosin hydrochloride capsules USP are indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes, including this drug. Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than one drug to achieve blood pressure goals. For specific advice on goals and management, see published guidelines, such as those of the National High Blood Pressure Education Programs Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC). Numerous antihypertensive drugs, from a variety of ...
BACKGROUND: Urine albumin excretion in the high normal range [urine albumin to creatinine ratio (UACR) 10-29 mg/g)] predicts hypertension in European-origin populations. However, the prognostic significance of UACR in the high normal range for incident hypertension is unclear in Indo-Asians. The objective of this study was to examine the relationship of normal to high normal levels of UACR and incident hypertension. METHODS: We conducted a nested cohort study within a cluster randomized controlled trial in Pakistan on 1272 normotensive non-diabetic adults aged ≥ 40 years with UACR/g. Incident hypertension was defined as new onset of systolic blood pressure (SBP) ≥ 140 mmHg or diastolic ≥ 90 mmHg or initiation of antihypertensive therapy. RESULTS: A total of 920 (72.3%) participants completed the 2-year final follow-up. During this time, 105 (11.4%) developed incident hypertension. In the multivariable model, the odds [95% confidence interval (CI)] for incident hypertension were 2.45(1.21-4.98)
TY - JOUR. T1 - Hypertension in chronic kidney disease and dialysis. T2 - Pathophysiology and management. AU - Agarwal, Rajiv. PY - 2005/8. Y1 - 2005/8. N2 - Hypertension affects 24% of the adult US population. In the United States, 3% of the adult population has an elevated serum creatinine level, and 70% of these patients have hypertension. The prevalence of hypertension in chronic kidney disease (CKD) depends on the patients age and the severity of renal failure, proteinuria, and underlying renal disease. As patients with CKD progress to end-stage renal disease (ESRD), 86% are diagnosed with hypertension. It has long been recognized that kidney function affects and is affected by hypertension. This article discusses the pathophysiology and management of hypertension in patients with CKD.. AB - Hypertension affects 24% of the adult US population. In the United States, 3% of the adult population has an elevated serum creatinine level, and 70% of these patients have hypertension. The prevalence ...
BACKGROUND:. Appropriately increased interest and concern about high blood pressure as a major public health problem coincided with the indication that the risks of hypertension-related morbidity and mortality could be reduced by reduction of blood pressure. Consensus suggestions that individualized approaches be used in treating patients with mild hypertension stimulated further investigations of non-pharmacological methods. Such investigations were also of considerable interest in relation to understanding the physiology of blood pressure control as well as the development of less costly non-drug therapies. Interest was heightened by information suggesting that there might be distinctly harmful side effects related to antihypertensive drug therapy, particularly thiazide diuretics, in some settings. Studies of non-drug therapies included dietary modifications primarily involving weight reduction and sodium restriction with increasing recent concern about other factors such as alcohol intake, ...
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The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure provides a new guideline for hypertension prevention and management. The following are the key messages(1) In persons older than 50 years, systolic blood pressure (BP) of m …
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Treatment of High blood pressure is abnormally high blood pressure with no known cause. Blood pressure measurements are read as two numbers. The higher number is called the systolic pressure. The lower number is called the diastolic pressure. Normal systolic pressure is 120 or less, and normal diastolic blood pressure is 80 or less, High blood pressure is defined as systolic pressure greater than 140 and/or diastolic pressure greater than 90. People with systolic blood pressures between 120 and 139, or diastolic pressures of 80 to 89 are considered pre-hypertensive and need medical monitoring and lifestyle changes, High blood pressure puts stress on the heart, lungs, brain, kidneys, and blood vessels. Over time, high blood pressure can damage these organs and tissues, High Blood Pressure, Hypertension, High Blood Pressure Causes, High Blood Pressure Symptoms, High Blood Pressure Treatment, Hypertension Definition, Chronic Hypertension, Effects Of High Blood Pressure, High Blood Pressure Cures, High
TY - JOUR. T1 - Initial therapy for uncomplicated hypertension. T2 - Insights from the alphabetic maze of recent studies. AU - Stewart, J. R.. AU - Yeun, Jane Y. PY - 2003/8. Y1 - 2003/8. N2 - Some hypertension treatment guidelines published in the late 1990s recommended that diuretics and β-blockers be used as 1st line drugs for treating uncomplicated hypertension, reserving new antihypertensive drugs for special indications. This recommendation is predicated on the fact that large trials showing cardiovascular protection with antihypertensive drugs used β-blockers and diuretics. Other guidelines suggested all antihypertensives are equal and that drug selection should be individualized. These disparate guidelines arise from the controversy over are all antihypertensives created equal? Since these guidelines, many large hypertension trials have been conducted. This paper will review the recent hypertension trials, the meta-analyses of some of these trials, highlight some of the flaws ...
TY - CHAP. T1 - Acute hypertensive response in intracerebral hemorrhage. AU - Hassan, Ameer E.. AU - Zacharatos, Haralabos. AU - Qureshi, Adnan I. PY - 2009/1/1. Y1 - 2009/1/1. N2 - Acute hypertensive response is the elevation of blood pressure above normal and premorbid values that initially occurs within the first 24 hours of symptom onset in patients with intracerebral hemorrhage (ICH). We reviewed the existing data pertinent to acute hypertensive response derived from scientific guidelines, randomized trials, non-randomized controlled studies, and selected observational studies. Chronic hypertension and intracerebral hemorrhage Incidence of intracerebral hemorrhage and hypertension Spontaneous, non-traumatic ICH from intraparenchymal blood vessels makes up approximately 8-15% of all strokes. Approximately 80-85% are primary spontaneous ICH which are either secondary to arterial hypertension or cerebral amyloid angiopathy. It is estimated that 70% of the primary spontaneous ICH cases are ...
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Many adults have high blood pressure and by the age of 55, more than half of all adults have high blood pressure. Less than half of Americans have their blood pressure under control. The consequences of uncontrolled blood pressure are many throughout the body, and can include damage to almost any organ, including the brain, heart, kidneys, and eyes. An extremely high blood pressure can result in serious damage in a relatively short period of time, even hours. It is important to understand, however, that even a moderately high blood pressure over time can result in serious organ disease as well.. The retina is perfused by a very fine vasculature, that is very fine arteries and veins, which are particulary susceptible to damage from high blood pressure. In many instances, a retinal specialist can note vascular changes consistent with chronic high blood pressure. Prevention of hypertensive disease by early diagnosis and treatment of high blood pressure is essential in avoiding unnecessary disease ...
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TY - JOUR. T1 - Metabolic Syndrome, Proteinuria, and the Risk of Progressive CKD in Hypertensive African Americans. AU - Lea, Janice. AU - Cheek, Deanna. AU - Thornley-Brown, Denise. AU - Appel, Lawrence. AU - Agodoa, Lawrence. AU - Contreras, Gabriel. AU - Gassman, Jennifer. AU - Lash, Jim. AU - Miller, Edgar R.. AU - Randall, Otelio. AU - Wang, Xuelei. AU - McClellan, William. PY - 2008/5/1. Y1 - 2008/5/1. N2 - Background: Chronic kidney disease (CKD) is more likely to progress to kidney failure (end-stage renal disease) in African Americans, although the reasons for this are unclear. Metabolic syndrome is a risk factor for the development of diabetes and cardiovascular disease and recently was linked to incident CKD. The purpose of this study is to examine whether metabolic syndrome is associated with kidney disease progression in hypertensive African Americans. Design & Participants: The current study design is a secondary analysis of the African-American Study of Hypertension and Kidney ...
1. Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J. Global burden of hypertension: analysis of worldwide data. Lancet 2005;365:217-223. 2. Go AS, Mozaffarian D, Roger VL, et al. Heart disease and stroke statistics - 2014 update: a report from the American Heart Association. Circulation 2014;129:e28-292. 3. Franklin SS. Cardiovascular risks related to increased diastolic, systolic and pulse pressure: an epidemiologists point of view. Pathol Biol (Paris) 1999;47:594-603. 4. Franklin SS, Jacobs MJ, Wong ND, LItalien GJ, Lapuerta P. Predominance of isolated systolic hypertension among middle-aged and elderly US hypertensives: analysis based on National Health and Nutrition Examination Survey (NHANES) III. Hypertension 2001;37:869-874. 5. Chobanian AV, Bakris GL, Black HR, et al. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 Report. JAMA 2003;289:2560-2572. 6. Collins R, Peto R, MacMahon S, et ...
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BACKGROUND: The recommendation of the Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC VI) to lower blood pressure (BP) in diabetic patients to less than 130/85 mm Hg may hav
As many as 50 percent of overweight men and women with high blood pressure may have hypertension as a result of being overweight, researchers reported today at the American Heart Associations 61st Annual Fall Conference of the Council for High Blood Pressure Research.Researchers in Italy found that about 50 percent of overweight, hypertensive adults, ranging in age from 29 to 65 years, achieved normal body weight and blood pressure after six months of treatment with a reduced-calorie diet.. For related information on high blood pressure and over weight, visit:. Over weight adults have high blood pressure than normal weight people. With high blood pressure and obesity, cardiovascular risk increases by increasing LDL cholesterol. According to the research, obesity increased cardiac output and blood volume and arterial resistance.. Obesity leads to high secretion of insulin in trying to reduce the concentration of excess sugar in blood. The secretion of this insulin is ...
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Novartis AG, Daiichi Sankyo Company Limited, Acetelion Ltd, Boehringer Ingelheim, Sanofi S.A., Astra Zeneca plc, Ranbaxy Laboratories Limited, Inc., Takeda Pharmaceuticals Company Limited, Pfizer Inc. are some of the prominent players at the forefront of competition in the Global Market of Anti-Hypertensive Drugs and are profiled in MRFR Analysis.. Get Free Sample Report @ According to a recent study report published by the Market Research Future, The global market of Anti-Hypertensive Drugs was valued at $32.2 billion in 2015, and is projected to reach $ USD 41.2 billion by 2023. Thus the market is anticipated to observe a sluggish growth; at a CAGR of 2.73% during 2016 to 2022.. Anti-Hypertensive Drugs are used to treat hypertension (high blood pressure). Hypertension is a state of chronic elevated arterial blood pressure at or greater than 140/90 mm Hg for adults. Hypertension is one of the most powerful risk factors for cardiovascular ...
Lower your blood pressure with one single amino acid If. Lower your blood pressure with one single amino. can lead to higher blood pressure by making your.Blood pressure is the amount of force exerted on the artery walls by the pumping blood. High blood pressure. blood pressure is. foods that contain.New MOOD is like a deep breath and a smile in a bottle. and maintaining blood pressure levels already in the normal range. loc_en_US, sid_New_MOOD___, stg,.While high blood pressure is more common,. Causes of Low Blood Pressure During Pregnancy. How to Raise Blood Pressure Naturally.Hyperkalemia (High Blood Potassium). High blood pressure can damage the kidneys and is one of the leading causes of kidney failure. Foods to Help You Concentrate.The Benefits of Black Walnut. People who are taking blood pressure medication should avoid. walnut are available for purchase online and in natural-foods.. ...
DR. WRIGHT: The results of SPRINT are very exciting. This study shows that intensive blood pressure management can prevent the cardiovascular complications of hypertension and save lives. As the NHLBI reported, treating high-risk hypertensive adults age 50 and older reduced cardiovascular events by 30 percent and reduced all-cause mortality by nearly 25 percent when compared with patients treated to a systolic target of 140 mm Hg. SPRINT was designed as a target-based study, which gave physicians flexibility in selecting antihypertensive medications to achieve the assigned blood pressure target. Hypertensive patients with a 10-year Framingham General cardiovascular risk ?15%, age ,75 years of age or pre-existing kidney disease were randomized to intensive blood pressure control (less than 120 mm Hg) or standard blood pressure control (less than 140 mm Hg). In the intensive-therapy arm, patients were treated with three or more antihypertensive medications, including diuretics, calcium channel ...
In light of the new Hypertension guidelines released this month, I wanted to write a post about Naturopathic approaches for blood pressure management. Hypertension, commonly referred to as, High Blood Pressure is a common health condition worldwide. There a variety of causes of hypertension, having to do with the heart, kidneys, liver, endocrine organs and the mind (stress and anxiety). Hypertension can cause symptoms such as palpitations, dizziness, fatigue, and vision changes, depending on how severe it is. Over the past few decades, we have come up with marvelous drugs that manage hypertension quite well. But did you know that most cases of primary essential hypertension are actually due to diet and lifestyle? Similar to many other non-communicable diseases, hypertension can be managed beautifully instead of or in addition to pharmaceutical medications! ...
The decision to appoint a committee for JNC 7 was based on four factors: the publication of many new hypertension observational studies and clinical trials since the last report was published in 1997; the need for a new, clear, and concise guideline that would be useful to clinicians; the need to simplify the classification of BP; and a clear recognition that the JNC reports did not result in maximum benefit to the public. This JNC report is presented in two separate publications. The initial Express version, a succinct practical guide, was published in the May 21, 2003 issue of the Journal of the American Medical Association. The current, more comprehensive report provides a broader discussion and justification for the recommendations made by the committee. As with prior JNC reports, the committee recognizes that the responsible physicians judgment is paramount in managing his or her patients.. Since the publication of the JNC 6 report, the NHBPEP Coordinating Committee, chaired by the ...
On average, a lower blood pressure goal was no better than the standard blood pressure goal at slowing progression of kidney disease among African-Americans who had chronic kidney disease resulting from high blood pressure, according to results of the African-American Study of Kidney Disease and Hypertension (AASK), the largest and longest study of chronic kidney disease (CKD) in African-Americans. However, the blood pressure goal did benefit people who also had protein in the urine, which is a sign of kidney damage. The study, funded by the National Institutes of Health, appears in the Sept. 2 issue of the New England Journal of Medicine.. Find good dental insurance - ...
High blood pressure is the most common chronic medical problem prompting visits to primary health care providers in USA. The American Heart Association estimated the direct and indirect costs of high blood pressure in 2010 as $76.6 billion.[144] In the US 80% of people with hypertension are aware of their condition, 71% take some antihypertensive medication, but only 48% of people aware that they have hypertension adequately control it.[144] Adequate management of hypertension can be hampered by inadequacies in the diagnosis, treatment, or control of high blood pressure.[164] Health care providers face many obstacles to achieving blood pressure control, including resistance to taking multiple medications to reach blood pressure goals. People also face the challenges of adhering to medicine schedules and making lifestyle changes. Nonetheless, the achievement of blood pressure goals is possible, and most importantly, lowering blood pressure significantly reduces the risk of death due to heart ...
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Most evidence about the effects of blood pressure on the risks of cardiovascular disease derives from two principal sources: prospective non-randomised observational studies of the associations between blood pressure and the incidence of stroke and of coronary heart disease, and randomised trials of antihypertensive drug therapy. The focus of the first part of this chapter concerns the evidence from observational studies, which--despite the possibility of confounding by other risk factors--may be more relevant to the eventual effects of prolonged blood pressure differences on stroke and coronary heart disease risk. The focus of the second part concerns the evidence from randomised trials of antihypertensive drug treatment, which are more relevant to assessing how rapidly, and to what extent, the epidemiologically expected reductions in stroke or in coronary heart disease are produced by suddenly lowering blood pressure in middle and old age.
Hypertensive African Americans often respond poorly to beta-blocker monotherapy, compared with whites. There is evidence, however, that suggests that this response may be different if beta-blockers with vasodilating effects are used. This 12-week, multi-center, double-blind, randomized placebo-controlled study assessed the antihypertensive efficacy and safety of nebivolol, a cardioselective, vasodilating beta1-blocker, at doses of 2.5, 5, 10, 20, or 40 mg once daily in 300 African American patients with stage I or II hypertension (mean sitting diastolic blood pressure [SiDBP] | or =95 mm Hg and | or =109 mm Hg). The primary efficacy end point was the baseline-adjusted change in trough mean SiDBP. After 12 weeks, nebivolol significantly reduced least squares mean SiDBP (P| or =.004) at all doses of 5 mg and higher and sitting systolic blood pressure (P| or =.044) at all doses 10 mg and higher, compared with placebo. The drug was safe and well-tolerated, with no significant difference in the incidence of
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As you slim down, it may be possible to reduce your dose of blood pressure medication - or stop taking your blood pressure medication completely. Dont make changes to your blood pressure medication on your own, however. Do so only after getting your doctors OK.. ...
Introduction: High sodium intake is an established risk factor for hypertension and cardiovascular diseases. The average sodium intake in Koreans was estimated at 4,645mg/day, which was more than two times compared to the recommended amount, 2000mg/day. We assessed whether people who diagnosed with hypertension or treated for hypertension consume less sodium than those without hypertension.. Methods: The present study analyzed data from a total of 6,577 Koreans (3,816 women and 2,761 men) aged 40 years and older, participated in the Korea National Health and Nutrition Examination Survey (KNHANES IV, 2007-2008). Participants were classified into five groups as follows: normal blood pressure, pre-hypertension, hypertension without treatment, hypertension with treatment, and hypertension with complications. The association between sodium intake and hypertension management status was estimated using exponential regression coefficient, adjusted for potential confounders including age, energy intake, ...
Hypertension is a major and correctable cardiovascular risk factor. The correct diagnosis of hypertension and precise assessment of cardiovascular risk are essential to give proper treatment in patients with hypertension. Although echocardiography is the second-line study in the evaluation of hypertensive patients, it gives many clues suggesting bad prognosis associated with hypertension, including increased left ventricular (LV) mass, decreased LV systolic function, impaired LV diastolic function, and increased left atrial size and decreased function. Along with conventional echocardiographic methods, tissue Doppler imaging, three-dimensional echocardiography, and strain echocardiography are newer echocardiographic modalities in the evaluation of hypertensive patients in the current echocardiographic laboratories. Understanding conventional and newer echocardiographic parameters is important in the diagnosis and assessment of cardiovascular risk in hypertensive patients.
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Increased blood pressure is a leading risk for premature death and disability.1 It is estimated that hypertension is the most costly cardiovascular disease, with overall direct costs to health similar to that for stroke, myocardial infarction and other ischemic heart diseases combined.2 Therefore, efforts to detect and control hypertension are of great importance for public health.. Recently, the National Institute for Health and Clinical Excellence in the United Kingdom updated their recommendations for the management of hypertension.3 One of the most substantive changes to their recommendations includes the incorporation of home and ambulatory blood pressure monitoring into the diagnosis of hypertension. These guidelines recommend ambulatory blood pressure monitoring if a patient has had two elevated blood pressure readings (≥ 140/90 mm Hg) during an office visit. If ambulatory monitoring is not available or tolerated, home monitoring should be used. The guidelines recommend pharmacotherapy ...
The most commonly diagnosed medical condition in the United States is high blood pressure, or hypertension, and blood pressure medications are among the top 10 most commonly prescribed drugs. However, these medications can cause undesirable side effects. Its better to address the underlying causes of high blood pressure-research shows diet and lifestyle changes are just as effective or even better than medications in lowering high blood pressure.. Why should you be concerned about high blood pressure? High blood pressure increases the risk of heart attack, heart failure, kidney failure, diabetes and peripheral vascular disease. Thirty percent of the population has high blood pressure, and another 30 percent has pre-hypertension, or somewhat elevated high blood pressure. Men are more likely than women to have high blood pressure before the age of 45, but after 65 the ratio reverses. African Americans and Mexican-Americans are at an increased risk.. ...
High blood pressure, or hypertension, is a condition in which blood pressure levels are measured above the normal ranges. Blood pressure is the force of blood in your arteries. Your blood pressure is high if it is 140/90 or higher. If you have diabetes or chronic kidney disease, 130/80 or higher is considered high blood pressure. High blood pressure increases the risk for heart attack, angina, stroke, kidney failure, and peripheral artery disease. High blood pressure can also cause arteries to age and lose elasticity faster that normal. High blood pressure may also increase the risk of developing fatty deposit in arteries (known as atherosclerosis). The risk of heart failure also increases due to the increased workload that high blood pressure places on the heart.. ...
Genetic hypertension[edit]. Dopamine receptor mutations can cause genetic hypertension in humans.[34] This can occur in animal ... Hussain T, Lokhandwala MF (2003). "Renal dopamine receptors and hypertension". Exp. Biol. Med. (Maywood). 228 (2): 134-42. doi: ... hypertension and obesity". J Hum Hypertens. 16 Suppl 1: S13-7. doi:10.1038/sj.jhh.1001334. PMID 11986886.. ...
Malignant hypertension[edit]. It could be useful for managing malignant hypertension due to end stage renal failure.[4] ... "Renal artery embolization for managing uncontrolled hypertension in a kidney transplant candidate". Avicenna J Med. 3 (1): 23- ...
Pulmonary arterial hypertension[edit]. Tadalafil 40 mg is approved in the United States, Canada, and Japan as a once-daily ... Tadalafil was approved in 2009 in the United States for the treatment of pulmonary arterial hypertension[18] and is under ... Tadalafil is used to treat erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and pulmonary arterial hypertension.[ ... In late November 2008, Eli Lilly sold the exclusive rights to commercialize tadalafil for pulmonary arterial hypertension in ...
Hypertension[edit]. *Hypertension non-compliance (93% in US, 70% in UK)[citation needed] is the main cause of uncontrolled ... As a result of poor compliance,[citation needed] 75% of patients with a diagnosis of hypertension do not achieve optimum blood- ... 1975). "Randomised clinical trial of strategies for improving medication compliance in primary hypertension". Lancet. 305 (7918 ... Journal of Hypertension. 27 (11): 2294-5, author reply 2295. doi:10.1097/hjh.0b013e328332a501. PMID 20724871.. ...
Cardiovascular and hypertension[edit]. Worldwide, one billion people suffer from hypertension. In the U.S., half of the 146 ... "Journal of the American Society of Hypertension : JASH. 9 (11): 885-901. doi:10.1016/j.jash.2015.08.009. PMC 4641765 . PMID ... In hypertension patients who suffer from vitamin D deficiency, UVB radiation (but not UVA) lowered blood pressure.[48] ... They are also more likely to suffer from cardiovascular disease, hypertension and organ cancer.[49][50][51] ...
Hypertension[edit]. Conditions, such as hypertension, that encourage increased left ventricular afterload can lead to ... Pulmonary hypertension and right ventricular dysfunction[edit]. Most HFpEF patients exhibit pulmonary hypertension which is ... "Hypertension. 60 (5): 1200-1206. doi:10.1161/hypertensionaha.112.202705. PMC 3522520. PMID 23033371.. CS1 maint: multiple names ... Hypertension, obesity, metabolic syndrome, and sedentary lifestyle have been identified as important risk factors for diverse ...
... due to general hypertension) tends to increase the duration of spontaneous epistaxis.[7] Anticoagulant medication and disorders ... "Is epistaxis evidence of end-organ damage in patients with hypertension?". Laryngoscope. 109 (7): 1111-1115. doi:10.1097/ ...
"Hypertension. 63 (4): 878-85. doi:10.1161/HYP.0000000000000003. PMID 24243703. Archived from the original on 20 November 2013. ...
Hypertension has been reported to occur very rarely with moclobemide therapy.[12] ...
1999). "Evidence for an interaction between adducin and Na(+)-K(+)-ATPase: relation to genetic hypertension". Am. J. Physiol. ... 1998). "Human alpha-adducin gene, blood pressure, and sodium metabolism". Hypertension. 32 (1): 138-43. doi:10.1161/01.HYP.32.1 ... Polymorphism in ADD1 is associated with hypertension. GRCh38: Ensembl release 89: ENSG00000087274 - Ensembl, May 2017 GRCm38: ... 1997). "Polymorphisms of alpha-adducin and salt sensitivity in patients with essential hypertension". Lancet. 349 (9062): 1353- ...
"Role of extracellular superoxide dismutase in hypertension". Hypertension. 48 (3): 473-81. doi:10.1161/01.HYP.0000235682.47673. ... "Hypertension. 55 (2): 277-83, 6p following 283. doi:10.1161/HYPERTENSIONAHA.109.142646. PMC 2813894. PMID 20008675.. ... In mice, the extracellular superoxide dismutase (SOD3, ecSOD) contributes to the development of hypertension.[40][41] ... "Induction of hypertension and peripheral inflammation by reduction of extracellular superoxide dismutase in the central ...
"Hypertension. 18 (1): 1-8. doi:10.1161/01.hyp.18.1.1. PMID 1677640.. ...
"Hypertension. 5: 776-777. doi:10.1161/01.HYP.5.5.772. Retrieved 19 September 2015.. ...
Hypertension. 40 (3): 355-60. doi:10.1161/01.HYP.0000028589.66335.AA. PMID 12215479.. ...
Hypertension in cats and dogs[edit]. Hypertension in cats and dogs is diagnosed if the blood pressure is greater than 150 mm Hg ... National Clinical Guideline Centre (UK) (2011). Hypertension: The Clinical Management of Primary Hypertension in Adults: Update ... Lee AJ (December 1997). "The role of rheological and haemostatic factors in hypertension". Journal of Human Hypertension. 11 ( ... Granger, Joey P.; Hall, John E. (2007). "Role of the Kidney in Hypertension". Comprehensive Hypertension. Elsevier. pp. 241-263 ...
... can lead to a reduction in hypertension (high blood pressure), however whether this reduces hypertension-related ... Harsha, D. W.; Bray, G. A. (2008). "Weight Loss and Blood Pressure Control (Pro)". Hypertension. 51 (6): 1420-25. CiteSeerX ...
Hypertension. 38 (4): 815-20. ISSN 0194-911X. PMID 11641292.. CS1 maint: Multiple names: authors list (link) ...
"Hypertension. 59 (2): 507-12. doi:10.1161/HYPERTENSIONAHA.111.184606. PMC 3266468. PMID 22203741. The development of the GPER- ...
Hypertension. 51 (6): 1545-51. doi:10.1161/HYPERTENSIONAHA.108.112003. PMID 18413485.. ...
International Society of Hypertension (ISH) statement on management of hypertension". J Hypertens. 21 (11): 1983-92. doi: ... They control hypertension in part by inhibiting reabsorption of sodium (Na+) and chloride (Cl−) ions from the distal convoluted ... Thiazide (/ˈθaɪəzaɪd/) is a type of molecule and a class of diuretics often used to treat hypertension (high blood pressure) ... They are the recommended first-line treatment in the US (JNC VIII) guidelines for hypertension and a recommended treatment in ...
Hypertension. 51 (2): 399-405. doi:10.1161/HYPERTENSIONAHA.107.098988. PMID 18086944.. CS1 maint: Multiple names: authors list ...
Apart from that the patient suffers from hypertension, type 2 diabetes with diabetic nephropathy, hysteromyoma, cholelithiasis ... Hypertension. 46 (2): 273-9. CiteSeerX doi:10.1161/01.HYP.0000172753.96583.e1. PMID 15983239.. ... hypertension and type 2 diabetes. Among the young obesity patients (from 18 to 29) more than two chronic diseases were found in ... development of brain infarction resulting from complications due to hypertensive crisis in patients suffering from hypertension ...
... associates with hypertension". Hypertension. 43 (3): 592-7. doi:10.1161/01.HYP.0000116224.51189.80. PMID 14744925. Cayla C, ...
There are more women than men with hypertension,[19] and, although men develop hypertension earlier in life,[20] hypertension ... Hypertension increases the risk of heart failure by two or three-fold[7] and probably accounts for about 25% of all cases of ... Hypertension or high blood pressure affects at least 26.4% of the world's population.[15] Hypertensive heart disease is only ... Stages of elevated BP and hypertension[7] Category. Systolic BP (mm Hg). Diastolic BP (mm Hg) ...
Hypertension. American Heart Association. 13 (6 Pt 2): 896-901. doi:10.1161/01.hyp.13.6.896. PMID 2786848. Archived from the ... The Zucker rat was bred to be a genetic model for research on obesity and hypertension. They are named after Lois M. Zucker and ... hypertension, and diabetes, using zinc-finger nuclease technology, are being commercialized by SAGE Labs. ... "The Zucker fatty rat as a genetic model of obesity and hypertension" (PDF) ...
Hypertension. 1,352. 2012[83]. 12%. Exjade (deferasirox). Chronic iron overload. 870. 2012[83]. 2%. Manufactured as tablets for ... Hypertension. Afinitor/Certican/Zortress (everolimus). Prevention of transplant rejection, various cancers. 797. 2012[83]. 80% ... both hypertension drugs), and the diabetes drug, Starlix.[120] Twenty-seven states, the District of Columbia and Chicago and ... in response to anticipated revenue downturns from the hypertension drug Diovan, which was losing patent protection, and the ...
Hypertension. 45 (2): 252-257. doi:10.1161/01.HYP.0000153517.44295.07. PMID 15642774.. ...
American College of Obstetricians Gynecologists; Task Force on Hypertension in Pregnancy (Nov 2013). "Hypertension in pregnancy ... Obesity, prior hypertension, older age, diabetes mellitus[2][4]. Diagnostic method. BP , 140 mmHg systolic or 90 mmHg diastolic ... Hypertension in pregnancy. ACOG. 2013. p. 2. ISBN 9781934984284. . Archived from the original on 2016-11-18.. ... Emile R. Mohler (2006). Advanced Therapy in Hypertension and Vascular Disease. PMPH-USA. pp. 407-408. ISBN 9781550093186. . ...
"American Journal of Hypertension. 30 (9): 876-883. doi:10.1093/ajh/hpx059. PMC 5861589. PMID 28520843.. ... the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European ... "Journal of Hypertension. 30 (3): 445-8. doi:10.1097/HJH.0b013e32834fa8b0. hdl:1765/73145. PMID 22278144.. ... "Journal of Hypertension. 31 (7): 1281-357. doi:10.1097/ PMID 23817082.. ...
Midodrine should only be taken during the daylight hours as it may promote supine hypertension.[84] ... "Hypertension. 58 (2): 167-75. doi:10.1161/HYPERTENSIONAHA.111.172262. PMC 3142863. PMID 21690484.. ...
... and also is exposed to exogenous factors that favor hypertension). The Platt school took the view that essential hypertension ... Inflammation, Autoimmunity, and Hypertension: The Essential Role of Tissue Transglutaminase. Author(s): Chen Liu, Rodney E ... Essential hypertension is one of the most common chronic diseases, as well as one of the leading risk factors for cardio- ... The Impact of Vitamin D in the Treatment of Essential Hypertension. Author(s): Christian Legarth, Daniela Grimm, Markus Wehland ...
Management of Resistant Hypertension. Resistant hypertension is defined as an average office BP of 130/80 mm Hg or higher in ... Strategies to Improve Hypertension Treatment and Control. Every adult with hypertension should have an evidence-based care plan ... Secondary Hypertension. A secondary cause of hypertension can be identified in approximately 10% of hypertensive adults, and ... Isolated systolic hypertension is the predominant form of hypertension in older persons. Randomized trials of antihypertensive ...
Trends in Hypertension from Health,United States. *Tables of Summary Health Statistics from the National Health Interview ... Hypertension Prevalence and Control Among Adults: United States, 2015-2016. *Characteristics of Visits to Primary Care ... Urban-rural Differences in Visits to Office-based Physicians by Adults With Hypertension: United States, 2014-2016 pdf icon[PDF ... Percent of adults aged 20 and over with hypertension (measured high blood pressure and/or taking antihypertensive medication): ...
Trends in Hypertension from Health,United States. *Tables of Summary Health Statistics from the National Health Interview ... Hypertension Prevalence and Control Among Adults: United States, 2015-2016. *Characteristics of Visits to Primary Care ... Percent of adults aged 20 and over with hypertension (measured high blood pressure and/or taking antihypertensive medication): ... Number of deaths from essential hypertension and hypertensive renal disease: 35,316. *Deaths per 100,000 population from ...
Secondary hypertension (or, less commonly, inessential hypertension) is a type of hypertension which by definition is caused by ... Williams B et al.; British Hypertension Society; Michael Sutters, MD (2006). "Secondary Hypertension". Hypertension Etiology & ... Hypertension secondary to endocrine disorders[edit]. *Neurogenic hypertension - excessive secretion of norepinephrine and ... Perioperative hypertension is development of hypertension just before, during or after surgery. It may occur before surgery ...
"How Is Pulmonary Hypertension Diagnosed?". National Heart, Lung, and Blood Institute.. *^ a b c d e f g Frank Gaillard. " ... WHO Group I" - Persistent pulmonary hypertension of the newborn WHO Group II - Pulmonary hypertension secondary to left heart ... "Pulmonary Hypertension. About Pulmonary Hypertension , Patient". Patient. Archived from the original on 2016-01-02. Retrieved ... eMedicine: radio/583 med/1962 Secondary pulmonary hypertension Pediatric primary pulmonary hypertension Persistent newborn ...
... hypertension), metabolism disorders, immune system problems, based on Nobel Prize discovery in Physiology... ... Hypertension Explained Clearly - Causes, Diagnosis, Medications, Treatment - Duration: 19:53. MedCram - Medical Lectures ... This is the best method to heal high blood pressure(hypertension), metabolism disorders, immune system problems, based on Nobel ... This method demonstrates really good statistics for treatment diseases such as Hypertension, Arthritis, Diabetes, Back pain, ...
British and Irish Hypertension Society., accessed April 2019. *Hypertension. PatientPlus., ... High blood pressure (hypertension) is a common medical condition where the pressure inside your arteries is higher than it ... Hypertension. Medscape., updated February 2019. *Williams B, Mancia G, Spiering W, et al. 2018 ESC/ ... Both hypertension and diabetes increase the risk of kidney disease and cardiovascular disease. If you have diabetes, you should ...
Hypertension is abnormally high blood pressure in the arteries, which are the blood vessels that carry blood from the heart to ... Hypertension usually has no symptoms, and many affected individuals do not know they have the condition. However, hypertension ... Hypertension can have a variety of causes. Secondary hypertension results from other disorders that raise blood pressure in ... Hypertension tends to run in families. Individuals whose parents have hypertension have an elevated risk of developing the ...
Learn about hypertension causes, your risks, and prevention. ... Hypertension puts you at higher risk for heart disease -- a ... Slideshow: A Visual Guide to High Blood Pressure Hypertension, or high blood pressure, is a common condition that will catch up ... High Blood Pressure Risk Factors The exact cause of hypertension is unknown, but there are several factors and conditions that ... Health Check: Assess Your Chances of Getting Hypertension Evaluate your personal health and your risks for big health problems. ...
Diagnosing hypertension is important. Learn how doctors test for high blood pressure and even see a photo of how the test is ... Diagnosing hypertension is important. Learn how doctors test for high blood pressure and even see a photo of how the test is ...
... also called hypertension, is more common in adults, but it can happen at any age. Learn what it is, how to prevent it, and how ... Hypertension (High Blood Pressure). Resources. Please Note: By clicking a link to any resource listed on this page, you will be ...
Medscapes Pulmonary Arterial Hypertension News & Perspectives provides a comprehensive medium containing the most up-to-date ... and clinically relevant material relating to the diagnosis and treatment of Pulmonary Arterial Hypertension. ... Inhaled Nitric Oxide Eases COVID-19-Related Exacerbation of Pulmonary Arterial Hypertension ...
Visit our Hypertension category page for the latest news on this subject, or sign up to our newsletter to receive the latest ... In fact, there were already some clues: the prevalence of hypertension is over 20% in Northeastern China compared to 10-14% in ... Study reveals link between hypertension and brain changes in rats New research investigates the changes in brain activity and ... "Hypertension And Chili Peppers." Medical News Today. MediLexicon, Intl., 5 Aug. 2010. Web.. 19 Sep. 2019. ,https://www. ...
Pulmonary hypertension (PH) is high blood pressure in the arteries to your lungs. It makes your heart work harder, which can ... HIV and Pulmonary Hypertension (Pulmonary Hypertension Association) - PDF * Liver Disease and Pulmonary Hypertension (Pulmonary ... Diet and Nutrition (Pulmonary Hypertension Association) * Exercise and Pulmonary Hypertension (PH) (Pulmonary Hypertension ... Methamphetamine Use and Pulmonary Hypertension (Pulmonary Hypertension Association) - PDF * Pulmonary Hypertension in ...
... with a particular focus on difficult-to-treat and resistant hypertension. The selected clinical cases are representative of the ... The scenarios considered include not only cases in which arterial hypertension is truly resistant but also instances of pseudo- ... resistant hypertension, including cases in which resistance is related to comorbidities, concomitant treatments, or the use of ... with a particular focus on difficult-to-treat and resistant hypertension. The selected clinical cases are representative of the ...
... with a particular focus on difficult-to-treat and resistant hypertension. The selected clinical cases are representative of the ... The scenarios considered include not only cases in which arterial hypertension is truly resistant but also instances of pseudo- ... Adult Patient with PseudoResistant Hypertension High Blood Pressure Induced by Exogenous Substances ... resistant hypertension, including cases in which resistance is related to comorbidities, concomitant treatments, or the use of ...
... or hypertension - can cause damage to your blood vessels and internal organs including your heart. ... Additionally, non-Hispanic Black Americans also are at higher risk of developing pre-hypertension and hypertension than non- ... Hypertension: Understanding a Silent Killer Reviewed by Esther Ellis, MS, RDN, LDN Published March 9, 2021 ... Individuals at risk of high blood pressure may be advised to follow the Dietary Approaches to Stop Hypertension diet to lower ...
Pulmonary arterial hypertension.. Farber HW1, Loscalzo J.. Author information. 1. Evans Department of Medicine, Boston ...
Hexamethonium in Hypertension. Br Med J 1951; 1 doi: (Published 28 April 1951) Cite this ...
In patients with chronic bronchitis and emphysema, the lack of oxygen contributes to pulmonary hypertension. The manifestations ... Other articles where Pulmonary arterial hypertension is discussed: cardiovascular disease: Pulmonary heart disease (cor ... In patients with chronic bronchitis and emphysema, the lack of oxygen contributes to pulmonary hypertension. The manifestations ...
... and UWO have shown that performing supervised moderate-intensity exercise during pregnancy can prevent gestational hypertension ... Gestational hypertension is high blood pressure detected after the 20th week of pregnancy in previously normotensive women. ... The prevalence of all pregnancies with some form of hypertension can be up to 10%. In spite of that the risks associated can ... "Exercise to control gestational hypertension." Medical News Today. MediLexicon, Intl., 18 Feb. 2016. Web.. 18 Sep. 2019. ,https ...
... treatment and complications of high blood pressure during pregnancy and pregnancy-induced hypertension. ... Tags: blood, chronic, chronicle, disorder, gestational, high, hypertension, hypertensive, nonproteinuric, pregnancy, pregnancy- ... Gestational hypertension can also turn into PIH.. *PIH: High blood pressure is not the main problem, but it is one of the main ... Pregnancy-induced hypertension (PIH), also called toxemia or preeclampsia: This condition can cause serious problems for both ...
... of hypertension occurs, often called malignant hypertension, that results in damage to small blood vessels throughout the body ... Other articles where Malignant hypertension is discussed: cardiovascular disease: Hypertensive heart disease: … ... In hypertension. Malignant hypertension is present when there is a sustained or sudden rise in diastolic blood pressure ... of hypertension occurs, often called malignant hypertension, that results in damage to small blood vessels throughout the body ...
In patients with sporadically elevated blood pressure or white coat hypertension, a 24-h ambulatory BP monitoring is useful. ... White coat hypertension Isolated systolic hypertension Sodium sensitivity Hypertensive retinopathy Renal artery stenosis ... The 2008 Canadian Hypertension Education Program recommendations for the management of hypertension: part 2-therapy, Can J ... Guidelines for the management of hypertension. Report of the Third Working Party of the British Hypertension Society. BMJ. 1999 ...
... even if their hypertension doesnt show up on clinical tests, say researchers in the journal Psychosomatic Medicine. ... Hypertension People who believe they have high blood pressure are more likely to suffer from depression, ... People who believe they have high blood pressure are more likely to suffer from depression, even if their hypertension doesnt ...
Primary pulmonary hypertension.. Gaine SP1, Rubin LJ.. Author information. 1. Division of Pulmonary and Critical Care Medicine ... Primary pulmonary hypertension (PPH) is a progressive disease characterised by raised pulmonary vascular resistance, which ...
Treatments and Tools for hypertension. Find hypertension information, treatments for hypertension and hypertension symptoms. ... hypertension - MedHelps hypertension Center for Information, Symptoms, Resources, ... Smoking, Hypertension Diabetes lead to Dementia-Whats bad for the heart is bad for the Brain ... 17th December 2009: hypertension, felt dreadful so went to the doctor. BP 175/115. Given b-... ...
A possible prescription for Hypertension with stress as a major factor: Hawthorn -- 2 parts Linden Blossom -- 1 part Yarrow -- ... A possible prescription for Hypertension with associate headache: Hawthorn -- 2 parts Linden Blossom -- 1 part Yarrow -- 1 part ... A possible prescription for Hypertension with depression: Hawthorn -- 2 parts Linden Blossom -- 1 part Yarrow -- 1 part St. ... A possible prescription for Hypertension with palpitations: Hawthorn -- 2 parts Linden Blossom -- 1 part Yarrow -- 1 part ...
Hypertension or high blood pressure occurs when the blood vessels of the arterial system become constricted forcing the heart ... Understanding Hypertension. Guest Author - Dr. Denise Howard. Hypertension or high blood pressure occurs when the blood vessels ... Finally, medications such as birth control pills and steroids can contribute to the development of hypertension.. Hypertension ... Long term uncontrolled hypertension can lead to damage to the organs of the body. If the heart has to work harder to pump blood ...
  • Secondary hypertension (or, less commonly, inessential hypertension ) is a type of hypertension which by definition is caused by an identifiable underlying primary cause. (
  • Congenital adrenal hyperplasia , a group of autosomal recessive disorders of the enzymes responsible for steroid hormone production, can lead to secondary hypertension by creating atypically high levels of mineralocorticoid steroid hormones. (
  • [11] A 1973 World Health Organization meeting was the first attempt to classify pulmonary hypertension by its cause, and a distinction was made between primary PH (resulting from a disease of the pulmonary arteries) and secondary PH (resulting secondary to other, non-vascular causes). (
  • it is classified as secondary hypertension. (
  • Secondary hypertension results from other disorders that raise blood pressure in addition to other problems. (
  • Secondary objectives include evaluating the efficacy of community BP measurement and SMS messaging for diagnosing hypertension in Aboriginal Canadian and rural Tanzanian people at risk of developing this health problem. (
  • Most of the causes of secondary hypertension in the younger adult are relatively uncommon in the elderly with the exception of renal artery stenosis. (
  • Secondary hypertension evaluation and treatment. (
  • Onusko E. Diagnosis of secondary hypertension. (
  • Secondary Hypertension results from intrinsic and extrinsic causes. (
  • Secondary hypertension is the condition when one can pinpoint the exact cause of hypertension. (
  • Kidney diseases is the most common factor for secondary hypertension. (
  • The OHSU Adult Nephrology and Hypertension clinic offers evaluation and treatment of all forms of primary and secondary hypertension, using both traditional and non-drug approaches. (
  • The center also specializes in the assessment and treatment of secondary hypertension (high blood pressure that has been linked to a specific cause). (
  • There are two types of hypertension which are the primary (essential) hypertension and secondary hypertension. (
  • Essential hypertension is referred to patients with hypertension without any secondary identifiable cause. (
  • Elevation of systolic and/or diastolic BP, either primary (essential hypertension) or secondary. (
  • Secondary hypertension is caused by an underlying condition, which tends to appear suddenly3. (
  • This syndrome is recognized by the WHO as pulmonary hypertension (PH) secondary to intrinsic lung disease. (
  • The reasons for secondary hypertension can be identifiable. (
  • The classification of primary and secondary pulmonary hypertension has been reclassified, and now is based on the main underlying disease or condition, symptoms, and treatment options for pulmonary hypertension . (
  • However, secondary pulmonary hypertension may occur in many types of diseases including congenital heart disease, lung disease, various connective tissue diseases and sickle cell disease. (
  • If we have normal-weight adolescent with important hypertension or symptomatic adolescent without positive family history, the possibility of secondary hypertension has to be thinking of and extended, on possible cause focused and stepwise diagnostics performed. (
  • High blood pressure is classified as primary (essential) hypertension or secondary hypertension. (
  • Hypertension with certain specific additional signs and symptoms may suggest secondary hypertension, i.e. hypertension due to an identifiable cause. (
  • It is much less common than the other type, called essential hypertension , affecting only 5-10% of hypertensive patients. (
  • This book is designed to assist physicians in the everyday management of hypertensive patients, with a particular focus on difficult-to-treat and resistant hypertension. (
  • Hypertensive retinopathy together with left ventricular hypertrophy and renal impairment are considered as an indicator of target organ damage There is positive evidence that treating hypertension in the elderly and very elderly provides clinical benefits. (
  • Within the field of hypertension, Dr. Sperati's particular interests are in fibromuscular dysplasia, atherosclerotic renal arterial disease, hyperaldosteronism, and genetic hypertensive syndromes (most involve the kidney). (
  • Hypertensive emergencies were previously known, in some cases, as malignant hypertension. (
  • Identify changes that will improve the lives of your hypertensive patients, and your practice, through this METRIC hypertension module. (
  • The Division of Nephrology and Hypertension offers a full range of clinical nephrology services, including care for patients with hypertension and chronic kidney disease. (
  • The Division of Nephrology and Hypertension at Nationwide Children's provides comprehensive treatment to children and adolescents with kidney and urinary tract problems. (
  • As the leader in pediatric care, the Division of Nephrology and Hypertension at Nationwide Children's provides comprehensive acute and chronic nephrology services, urinary tract evaluation, dialysis, kidney transplantation, hypertension diagnostics and management, as well as treatment of metabolic bone disease. (
  • The Division of Nephrology and Hypertension is staffed by pediatric experts who provide patients and their families unparalleled and innovative care. (
  • John David Spencer, MD, is chief of the Division of Nephrology and Hypertension, Principal Investigator in the Center for Clinical and Translational Research in the Abigail Wexner Research Institute at Nationwide Children's Hospital and an Associate Professor of Pediatrics at the Ohio State University College of Medicine. (
  • Hiren Patel, MD, is section chief of the Division of Nephrology and Hypertension and medical director of the Kidney Transplant Program at Nationwide Children's Hospital. (
  • This chapter will provide an update in the clinical management of hypertension in the elderly. (
  • Management of hypertension in the elderly patient. (
  • Pimenta E, Oparil S. Management of hypertension in the elderly. (
  • Authoritative and eminently readable, Hypertension Medicine constitutes a highly practical account of the challenging issues faced daily by family physicians, internists, and general practitioners in the evaluation and optimal management of hypertension. (
  • Weight control in the management of hypertension. (
  • Finally, medications such as birth control pills and steroids can contribute to the development of hypertension. (
  • Autonomic nervous system also has a major role to play in development of hypertension. (
  • Hypertension usually has no symptoms, and many affected individuals do not know they have the condition. (
  • Renal Artery Stenosis and High Blood Pressure Learn about the causes, symptoms, and treatments of renal artery stenosis, which often leads to hypertension. (
  • Ocular hypertension has no noticeable signs or symptoms. (
  • Currently affecting nearly half of adults in the United States, hypertension has been called a silent threat because the condition itself has no symptoms. (
  • Besides, preeclampsia might lead to eclampsia which is an extreme complication in pregnant women and their fetus.Although the gestational hypertension origin is unknown, there are numerous theories that suggest that pathophysiological processes lead to gestational hypertension and preeclampsia from the beginning of the pregnancy, though the maternal symptoms do not appear until mid- to late pregnancy. (
  • Hypertension in its early stages doesn t cause any noticeable symptoms. (
  • What are the symptoms of pulmonary hypertension? (
  • Symptoms of pulmonary hypertension do not always appear right away. (
  • The hardest part is to convince patients to keep taking the pills, because hypertension has no painful symptoms until oops! (
  • What are signs and symptoms of diastolic hypertension? (
  • Diastolic hypertension or general hypertension may or may not cause signs or symptoms. (
  • Play media Hypertension is rarely accompanied by symptoms, and its identification is usually through screening, or when seeking healthcare for an unrelated problem. (
  • Total health care spending for those with hypertension grew by 18.3 percent from 2012 to 2016. (
  • In 2016, spending by hypertension patients was 3.2 times higher than those without the condition. (
  • Varda, N. (2016) Hypertension in Adolescent. (
  • [11] Coughing up of blood may occur in some patients, particularly those with specific subtypes of pulmonary hypertension such as heritable pulmonary arterial hypertension, Eisenmenger syndrome and chronic thromboembolic pulmonary hypertension . (
  • As a PHCC, we participate in the PHA Registry (PHAR), a multi-center, prospective, observational registry of newly evaluated patients diagnosed at accredited U.S. centers with either pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension (CTEPH). (
  • It is designed to improve the ability of patients with chronic thromboembolic pulmonary hypertension to exercise. (
  • Pediatric Care Online: AAP Guidelines for Childhood Hypertension (Webinar) - Dr. Flynn discusses changes to the new American Academy of Pediatrics childhood hypertension guideline and how these changes will affect the management of children and adolescents with high blood pressure. (
  • Neurogenic hypertension - excessive secretion of norepinephrine and epinephrine which promotes vasoconstriction resulting from chronic high activity of the sympathoadrenal system , the sympathetic nervous system and the adrenal gland . (
  • DOC has blood-pressure raising effects similar to aldosterone, and abnormally high levels result in hypokalemic hypertension. (
  • [16] At high concentrations cortisol can cross-react and activate the mineralocorticoid receptor, leading to aldosterone -like effects in the kidney , causing hypertension. (
  • High blood pressure (hypertension) is a common medical condition where the pressure inside your arteries is higher than it should be. (
  • Hypertension is abnormally high blood pressure in the arteries, which are the blood vessels that carry blood from the heart to the rest of the body. (
  • High blood pressure, also known as hypertension, affects millions -- including children and teens. (
  • Slideshow: A Visual Guide to High Blood Pressure Hypertension, or high blood pressure, is a common condition that will catch up with most people who live into older age. (
  • High Blood Pressure Risk Factors The exact cause of hypertension is unknown, but there are several factors and conditions that may contribute to its occurrence. (
  • Preventing High Blood Pressure About one in every four American adults has high blood pressure -- also know as hypertension. (
  • If you develop high blood pressure when you're pregnant , you have gestational hypertension . (
  • Adult patients with uncontrolled hypertension can be enrolled into the BP control study, and those without hypertension but at high risk of developing this condition into the BP screening study if they meet the study inclusion criteria and have none of the exclusion criteria. (
  • Pulmonary hypertension (PH) is high blood pressure in the arteries to your lungs. (
  • Pulmonary hypertension is a rare, life-threatening condition that causes high blood pressure in the lungs and right side of the heart. (
  • Chronically high blood pressure - or hypertension - can cause damage to your blood vessels and internal organs including your heart. (
  • Individuals at risk of high blood pressure may be advised to follow the Dietary Approaches to Stop Hypertension diet to lower their blood pressure. (
  • Gestational hypertension is high blood pressure detected after the 20th week of pregnancy in previously normotensive women. (
  • High blood pressure (also called hypertension) occurs when your blood moves through your blood vessels at a higher pressure than normal. (
  • is the condition known as malignant hypertension, or accelerated hypertension, which arises when the blood pressure attains extremely high levels, the diastolic figure (the blood pressure between heart contractions) being 140 millimetres of mercury or higher (the normal being around 80). (
  • People who believe they have high blood pressure are more likely to suffer from depression, even if their hypertension doesn't show up on clinical tests, say researchers in the journal Psychosomatic Medicine. (
  • Dr. Cingolani has been recognized by the Council for High Blood Pressure Research of the American Heart Association for his work in hypertension and is the 2011 recipient of the PJ Schafer Memorial Heart Research Award. (
  • High blood pressure or Hypertension is a leading cause of heart attack and stroke in the US. (
  • Hypertension or high blood pressure occurs when the blood vessels of the arterial system become constricted forcing the heart to work harder to pump the blood to the tissues of the body. (
  • Hypertension is also known as high blood pressure. (
  • White coat hypertension, sometimes called white coat syndrome, is a phenomenon where patients appear to have high blood pressure in a clinical setting, but not in other settings, such as at home. (
  • If you do have white coat hypertension, it's possible that you will go on to develop high blood pressure in the future. (
  • Although ocular hypertension is mostly asymptomatic, chronically high eye pressure can trigger glaucomatous optic neuropathy (disc changes and visual field defects). (
  • Given that medications can be expensive and side effects and poor adherence are possible, it is important to categorize patients with ocular hypertension as low, moderate, or high risk before initiating treatment. (
  • Pulmonary Hypertension is a simplified name for a complex health problem: high blood pressure in the lungs. (
  • Hypertension is word that is used to describe high blood pressure .Blood pressure is the force the blood produces against the arterial wall as your heart pumps. (
  • About 70 million people in the United States have hypertension (High Blood Pressure Frequently Asked Questions , 2015). (
  • Hypertension Sha'mes Lashawn Handford Moss Point High School November 16, 2012 Abstract Hypertension is the most chronic medical condition that adults have. (
  • Hypertension Hypertension, also known as high blood pressure is starting to become a very common cardio vascular diagnosis. (
  • High blood pressure, also known as hypertension, is the most common cardiovascular disease. (
  • Hypertension, or high blood pressure, is a common condition. (
  • Pulmonary hypertension means high blood pressure in the lungs. (
  • Idiopathic pulmonary arterial hypertension (IPAH) is a lung disorder characterized by high blood pressure in the pulmonary arteries. (
  • IPAH and other forms of pulmonary hypertension are dangerous because high blood pressure in your pulmonary arteries strains your heart and causes serious heart and lung problems. (
  • Pulmonary arterial hypertension (PAH) is a condition involving high blood pressure and structural changes in the walls of the pulmonary arteries, which are the blood vessels that connect the right side of the heart to the lungs. (
  • High blood pressure, or hypertension, afflicts an estimated 60 million Americans, and physicians routinely prescribe several drugs to lower blood pressure, but in 90 percent of the cases they have no idea what causes it. (
  • If you have a blood pressure reading of 140/90 or higher, you're considered to have high blood pressure (also known as hypertension). (
  • Pulmonary hypertension (pronounced PULL-mun-airy hi-per-TEN-shun) is high blood pressure in the lungs. (
  • A diet high in monounsaturated fatty acids (MUFAs) is found to significantly decrease the risk of new-onset hypertension. (
  • High blood pressure, or hypertension , is when the force of the blood pushing on the blood vessel walls is too high. (
  • COLUMBIA, S.C., May 20 (UPI) -- People who have a parent with high blood pressure can reduce their risk of hypertension with moderate exercise, U.S. researchers say. (
  • The study, published in the journal Hypertension, found high levels of fitness were associated with a 42 percent lower risk of developing hypertension, and moderate levels of fitness with a 26 percent lower risk. (
  • Working adults with hypertension - abnormally high blood pressure - have spent three times more on health care than those without it, the Health Care Cost Institute reported. (
  • When these pressures are abnormally high, the person is diagnosed as having high blood pressure (systemic hypertension). (
  • One of the obstacles in treating hypertension is getting people to take it seriously, partly because of myths such as these: * Myth: Hypertension only strikes people who eat high-cholesterol, high-sodium foods and who don't get enough exercise. (
  • About 50 million Americans--one in five--have high blood pressure, or hypertension, as it's more formally known. (
  • Predicting who will get high blood pressure is an inexact science, but two recent studies suggest that you are more likely to have hypertension if you are toothless or have trouble metabolizing sugar. (
  • Millions of people classified with high blood pressure may not really have the problem after all, according to a provocative UCLA study that counters the prevailing wisdom and questions government health guidelines for treating hypertension. (
  • Renal failure (kidney failure) is caused primarily by chronic high blood pressure (hypertension) over many years. (
  • In addition, many people with diabetes also have hypertension, thus high blood pressure plays an even larger role in kidney failure. (
  • Other families with high rates of hypertension have also been studied. (
  • African Americans are at particularly high risk for both hypertension and renal failure and have four times the number of ESRD cases as Caucasians. (
  • Elevated systolic or diastolic pressure is called hypertension or high blood pressure . (
  • The PHA PHCC Accreditation Program is a critical landmark, as patients now have a means to find high-quality pulmonary hypertension programs throughout the U.S. (
  • A new study reveals that bipolar patients with high blood pressure suffer higher levels of mania than individuals without hypertension. (
  • Researchers discovered nearly half of patients hospitalized with bipolar disorder may suffer from hypertension, and the younger a person is diagnosed with the psychiatric condition the more likely they are to develop high blood pressure. (
  • High anxiety and white coat hypertension. (
  • High blood pressure, or hypertension, may soon be able to be detected through genes. (
  • Published in the Feb. 11 issue of the journal Science, the study's findings identified two mutations in the KCNJ5 gene, which codes for the high secretion of aldosterone, a hormone that causes hypertension. (
  • What better way to celebrate your pregnancy than with high quality Hypertension Maternity T-Shirts. (
  • If the blood pressure is slightly above this, but not yet high enough to be called true hypertension, it is currently called "pre-hypertension. (
  • The U.S. Centers for Disease Control reports that nearly 33 percent of American adults live with hypertension or high blood pressure. (
  • The Hypertension Clinic specializes in the treatment of difficult to manage high blood pressure. (
  • Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. (
  • Paroxysmal hypertension is episodic and volatile high blood pressure, which may be due to stress of any sort, or from a pheochromocytoma, a type of tumor involving the adrenal medulla. (
  • The differential diagnosis of a renal tumor in a young patient with hypertension includes Juxtaglomerular cell tumor , Wilms' tumor , and renal cell carcinoma , all of which may produce renin. (
  • By presenting clear, insightful, balanced reviews that emphasize recently published papers of major importance, the journal elucidates current and emerging approaches to the diagnosis, treatment, management, and prevention of conditions associated with hypertension. (
  • Early diagnosis and treatment of hypertension can prevent significant morbidity and premature mortality. (
  • Percentage of patients aged 18-85 years of age with a diagnosis of hypertension whose blood pressure improved during the measurement period. (
  • Cardiac conditions to consider in the differential diagnosis of neonatal hypertension include thoracic aortic coarctation. (
  • Hypertension in infancy: diagnosis, management and outcome. (
  • Careful measurements of blood flows and pressures define the diagnosis of pulmonary hypertension. (
  • Time to Abandon Clinic Blood Pressure for the Diagnosis of Hypertension? (
  • Pulmonary hypertension is abnormally elevated pressure in the pulmonary circulation. (
  • Pulmonary hypertension occurs when the pressure in the pulmonary arteries increases abnormally. (
  • When pressure in the pulmonary circulation becomes abnormally elevated, it is referred to as pulmonary hypertension. (
  • Hypertension can also be produced by diseases of the renal arteries supplying the kidney. (
  • The focus of Dr. Appel's investigative career is the conduct of clinical, epidemiologic and translational research pertaining to the prevention of hypertension, cardiovascular disease, and kidney disease, especially through sodium reduction and weight control. (
  • SEATTLE -- Preclinical kidney dysfunction may identify patients who are destined to develop hypertension, providing an early opportunity for intervention, investigators here concluded. (
  • Hypertension affects approximately 75 million adults in the United States and is a major risk factor for stroke, myocardial infarction ( aka heart attack), Coronary artery disease (CAD) and other vascular diseases, diabetis II, and chronic kidney disease. (
  • We emphasize a holistic approach to patient-care and offer non-pharmacologic, as well as traditional, approaches to both hypertension and kidney failure. (
  • Concept 1: Renal Artery Stenosis as the Cause of Renovascular Hypertension Renovascular hypertension is most commonly caused by prerenal factors, which are conditions that result in a decrease in blood flow to the kidney, which is also known as hypoperfusion. (
  • It is believed that most cases of hypertension leading to kidney failure have a genetic element. (
  • Animal studies have been done to find genetic linkages to hypertension and kidney failure, but genetic studies on humans are in their infancy. (
  • People of all ages, races, and both sexes may develop kidney failure due to hypertension. (
  • Your doctor may order blood tests to assess your cholesterol levels , kidney function, etc. to determine the cause of your hypertension. (
  • Hypertension is a contributing risk factor in the development of heart disease, stroke, chronic kidney disease and peripheral vascular disease, but it is usually only detected incidentally during a routine physical exam. (
  • Finding the right clinical trial for Essential hypertension can be challenging. (
  • He is a fellow of the American Society of Hypertension (ASH) and a Designated ASH Specialist in clinical hypertension. (
  • Describe the clinical presentation of neonatal hypertension. (
  • The study, which appears today in the Lancet medical journal, drew sharp criticism from hypertension researchers, who said it ignored extensive clinical evidence on the benefits of controlling hypertension. (
  • There is a large clinical relevance to the finding hypertension could be linked to the severity of bipolar disorders," he said. (
  • Reuters) - Bayer AG's experimental drug to treat two types of pulmonary hypertension worked well in clinical trials and should be approved, but at lower doses than those proposed by the company, according to medical reviewers at the U.S. Food and Drug Administration. (
  • We have access to clinical research trials designed to treat uncontrolled hypertension and associated risk factors. (
  • citation needed] Patients with paroxysmal hypertension who test negative for pheochromocytoma are said to be suffering from a clinical entity called "pseudopheochromocytoma. (
  • In patients with sporadically elevated blood pressure or white coat hypertension, a 24-h ambulatory BP monitoring is useful. (
  • White coat hypertension may affect as many as 25 per cent of people in the UK and is more common if you're pregnant or as you get older. (
  • How can I reduce my risk of having white coat hypertension? (
  • A recent study cites white coat hypertension, a term coined for people whose blood pressure rises in the presence of a doctor. (
  • White coat hypertension is the increase in blood pressure experienced by many people, especially women ² when being tested at the local clinic . (
  • The Pulmonary Hypertension Association (PHA) is a non-profit health organization, serving patients with pulmonary hypertension, their family members and the medical professionals who treat them. (
  • Part of Cincinnati Children's Heart Institute , the Pulmonary Hypertension Clinic provides comprehensive diagnostic and long-term treatment and follow-up for patients with pulmonary hypertension. (
  • The drug is also being developed to improve exercise ability in patients with pulmonary arterial hypertension. (
  • If the doctor is not sure of the cause, it is called idiopathic pulmonary hypertension. (
  • In this instance, "idiopathic" means that the cause of the pulmonary artery hypertension is unknown. (
  • While many forms of pulmonary hypertension have known triggers, idiopathic pulmonary arterial hypertension is different. (
  • There is no readily available cure for idiopathic pulmonary hypertension. (
  • Rarely, the cause of pulmonary hypertension is not known, and then we call it idiopathic. (
  • Pulmonary hypertension can have no identifiable cause and is then referred to as idiopathic pulmonary hypertension (formerly called primary pulmonary hypertension). (
  • Pulmonary hypertension may be idiopathic. (
  • To receive news and publication updates for International Journal of Hypertension, enter your email address in the box below. (
  • Even with gestational hypertension, you have a good chance of having a healthy pregnancy and baby since most women with this condition do. (
  • Gestational hypertension can lead to preeclampsia . (
  • Researchers at UPM and UWO have shown that performing supervised moderate-intensity exercise during pregnancy can prevent gestational hypertension in pregnant women and overweight in newborns. (
  • The most important factors that predispose pregnant women to hypertension are prepregnancy obesity , excessive weight gain during pregnancy and gestational diabetes . (
  • The existence of hypertension may occur before being pregnant but eventually it develops to a pregnancy complication in the long run during pregnancy known as gestational hypertension (GH). (
  • Thus, chronic hypertension increases the risk for cardiovascular disease and other serious health issues. (
  • Running head: GARLIC IN PATIENTS WITH HYPERTENSION !2 Introduction Hypertension is one of the most influential risk factors for cardiovascular disease, which can quickly threaten human health. (
  • Hypertension is classified as a cardiovascular disease caused by elevated blood pressure (Mosby's, 2006, p. 923). (
  • Providing a comprehensive, multidisciplinary team approach to managing hypertension, this approach has been proven to slow the progression of cardiovascular disease. (
  • Pregnancy-induced hypertension (PIH), also called toxemia or preeclampsia: This condition can cause serious problems for both the mother and the baby if left untreated. (
  • In many cases, the prerenal factor that causes renovascular hypertension is renal artery stenosis. (
  • The calculator aims to improve the early identification and treatment of hypertension in the outpatient setting. (
  • People with neurogenic hypertension respond poorly to treatment with diuretics as the underlying cause of their hypertension is not addressed. (
  • This method demonstrates really good statistics for treatment diseases such as Hypertension, Arthritis, Diabetes, Back pain, Immune system pathology and others. (
  • Treatment of hypertension: Insights from the JNC-VI Report. (
  • MRC Trial of treatment of mild hypertension: principal results. (
  • Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomized trial. (
  • Duprez D. Treatment of isolated hypertension in the elderly. (
  • Research into the control of blood pressure and the pathogenesis of hypertension is progressing rapidly, and a wide range of treatment choices is now available. (
  • Also examined in detail are the principal underlying mechanisms of hypertension, particularly those that help explain treatment choices, as well as the best techniques for successfully evaluating patients before treatment. (
  • However the multi-factorial etiology of hypertension limit the value of the concept of a specific in its treatment. (
  • There are a plethora of factors that have been identified as being important in the cause and treatment of essential hypertension. (
  • Brinerdine is reserpine: a drug used for the treatment of hypertension , which has its mode of action on the central nervous system. (
  • For example, there is a German Reserpine in Hypertension Study Group that have done research on initiating treatment of mild to moderate hypertension with a low dose combination of reserpine and the thiazide diuretic, clopamide in comparison to other treatments. (
  • According to the Ocular Hypertension Treatment Study (OHTS) , about 2% of people with untreated ocular hypertension develop glaucoma in one year, and 9.5% develop glaucoma in 5 years. (
  • Resistant hypertension is defined in this study as a systolic blood pressure in the office above 160 despite treatment with at least three blood pressure drugs, one of which is a diuretic. (
  • The teaching plan provides the overall blueprint or outline for instructions that Cleary defines the relationship among the behavioral, objectives, instructional content, teaching strategies , time frame for teaching , and methods of evaluation"( Redman p335).We spoke about that there is no cure for hypertension and that it can be controlled with the appropriate treatment. (
  • Blowey DL, Duda PJ, Stokes P, Hall M. Incidence and treatment of hypertension in the neonatal intensive care unit. (
  • Sahu R, Pannu H, Yu R, Shete S, Bricker JT, Gupta-Malhotra M. Systemic hypertension requiring treatment in the neonatal intensive care unit. (
  • A protein with a role in sensing cell damage and viral infections is a new target for the treatment of pulmonary hypertension, or increased blood pressure in the lungs, according to research led by Virginia Commonwealth University and the University of Sheffield in the United Kingdom. (
  • During 1991 and 1992, three major interventional trials dealt with hypertension in older subjects and the value of antihypertensive treatment in the elderly. (
  • These were the American Systolic Hypertension in the Elderly Program [‎SHEP]‎, the Swedish Trial in Old Patients with Hypertension [‎STOP-Hypertension]‎, and the British Medical Research Council Trial on treatment of hypertension in older adults. (
  • Describe at 2 approaches for the treatment of neonatal hypertension. (
  • The treatment for pulmonary hypertension can include oxygen, diuretics, blood thinners, medications that open the pulmonary arteries, and treatments for any underlying disease. (
  • 2 Despite a wealth of treatment options, half of all hypertension patients struggle to keep blood pressure at target levels. (
  • Clinicians strive to work closely with primary care providers, providing expert, experienced treatment of hypertension cases of all degrees. (
  • of hypertension occurs, often called malignant hypertension, that results in damage to small blood vessels throughout the body but particularly affecting the heart, brain, and kidneys. (
  • Malignant hypertension is present when there is a sustained or sudden rise in diastolic blood pressure exceeding 120 mmHg, with accompanying evidence of damage to organs such as the eyes, brain, heart, and kidneys. (
  • An exciting and promising new procedure, which can help lower blood pressure in patients with resistant hypertension (hypertension not controlled by medication), is currently under study in 90 medical centers, including ours, throughout the U.S. The procedure, called renal denervation, involves interrupting nerves of the sympathetic nervous system that connect the brain and the kidneys as they course through the renal arteries (the arteries to the kidneys). (
  • It is said to be that only five percent of patients with hypertension have an identifiable cause5. (
  • EQIPP: Hypertension (Online course) - This course focuses on best practices in identifying and managing patients with hypertension, as well as on how children without hypertension can maintain a healthy blood pressure through proper nutrition, exercise, and other lifestyle behaviors. (
  • Hypertension Calculator - Designed to aid primary care pediatricians and subspecialists in determining blood pressure percentiles at the point of care. (
  • Pulmonary hypertension ( PH or PHTN ) is a condition of increased blood pressure within the arteries of the lungs . (
  • Rare, genetic forms of hypertension are caused by mutations in particular genes, many of which help control the balance of fluids and salts in the body and affect blood pressure. (
  • Because these genes play an integral role in normal blood pressure control, researchers suspect that variations in them might impair blood pressure control and contribute to hypertension. (
  • Other genes associated with essential hypertension are important for the normal function of the lining of blood vessels (the vascular endothelium ). (
  • Australian National Blood Pressure Management Committee: The Australian Therapeutic Trial in Mild Hypertension. (
  • He is an expert in non-pharmacologic therapy to lower blood pressure and improve hypertension control. (
  • If the blood pressure reaches 140/90 or higher on two separate occasions, the person is said to suffer from hypertension. (
  • When the blood pressure is slightly higher than 120/80, such condition is termed as pre-hypertension. (
  • This type of blood pressure where exact cause cannot be pinpointed is known as essential hypertension (or primary hypertension). (
  • IRVINE, Calif. -- Three of every four adults with symptomatic heart disease have hypertension and in one-half to two-thirds of those people blood pressure is uncontrolled or poorly controlled. (
  • Hypertension is defined as a systolic blood pressure (SBP) above 140 mm Hg, or a diastolic blood pressure (DBP) above 90 mm Hg at rest. (
  • PHA also funds cutting-edge research on pulmonary hypertension in collaboration with the National Heart, Lung, and Blood Institute, the American Thoracic Society and the American Heart Association. (
  • Hypertension is defined as a blood pressure reading of 140/90mmHg (millimeters of mercury) or above. (
  • Hypertension is defined as blood pressure greater than 140/90 mm Hg on two or more blood pressure readings taken at each of two or more visits after initial screening. (
  • So patients who have hypertension are at a possible risk to developing a serious disease caused by this increase in blood pressure. (
  • We do understand that injury to the lining of the blood vessels leads to specific chemical imbalances that participate in pulmonary hypertension. (
  • If you have pulmonary hypertension, increased blood pressure occurs in thickened and narrowed arterial blood vessels in your lungs and reduces blood flow. (
  • The main effect of pulmonary hypertension is that it causes the right ventricle to work harder to pump blood to the lungs. (
  • Some heart defects can cause pulmonary hypertension because they direct more blood than normal to the pulmonary artery. (
  • Blood pressure above 139/89 is considered hypertension. (
  • The opposite of Hypertension is Hypotension , referring to low blood pressure. (
  • In general, Hypertension is the direct result of thick blood. (
  • Of course, we shouldn't go overboard: Oregon only looked at hypertension , cholesterol, and blood sugar. (
  • Kids with severe hypertension should not do any weightlifting or power-lifting, bodybuilding, or strength training until their blood pressure is under control and a doctor says it's OK. (
  • Risk factors for pulmonary hypertension are liver failure, chronic lung disease, blood clotting disorders, and underlying diseases, such as scleroderma, dermatomyositis , and systemic lupus erythematosus . (
  • Less commonly, pulmonary hypertension results from constriction, or stiffening, of the pulmonary arteries that supply blood to the lungs, so called pulmonary arterial hypertension (PAH). (
  • Blood pressure is elevated, and even patients who did not have hypertension prior to the onset of ESRD will develop hypertension. (
  • Diastolic hypertension, where only your diastolic blood pressure is elevated, may be treated with lifestyle changes such as weight loss , reducing your sodium intake or alcohol consumption , and quitting smoking. (
  • Pulmonary hypertension results from increased resistance to blood flow through the pulmonary vasculature (due to progressive muscular thickening and fibrosis of the blood vessels in the lungs). (
  • Genetic hypertension affects many people, he said, and now, with a simple blood test, a person could find out if they have the genes for hypertension. (
  • Quantitative evaluation of myocardial layer-specific strain using two-dimensional speckle tracking echocardiography among young adults with essential hypertension in China. (
  • The myocardial wall of the left ventricle is a complex, multilayered structure, which is altered in young adults with hypertension. (
  • Hypertension affects an estimated 29 percent of adults in the United States. (
  • Most costly of all were patients approaching eligibility for Medicare, age 55 to 64, whose care accounted for more than half of all spending by adults with hypertension, the Institute found. (
  • Hypertension in adolescents is, as in other patients, one of the important cardiovascular risk factors, associated with hypertension in adults and with appearance of cardiovascular complications later in life. (
  • Ocular hypertension occurs when the pressure in your eyes is above the range considered normal with no detectable changes in vision or damage to the structure of your eyes. (
  • Ocular hypertension can occur in people of all ages, but it occurs more frequently in African Americans, people over age 40 and people with family histories of ocular hypertension and/or glaucoma. (
  • This most commonly occurs when the pulmonary venous pressure is elevated, so called pulmonary venous hypertension (PVH). (
  • In the genetic field, this discovery found the genes where mutation occurs, which code for the hormone that causes hypertension," Choi said. (
  • and the following partnering professional organizations: American Academy of Physician Assistants, Association of Black Cardiologists, American College of Preventive Medicine, American Geriatrics Society, American Pharmacists Association, American Society of Hypertension, American Society for Preventive Cardiology, National Medical Association, and Preventive Cardiovascular Nurses Association. (
  • Dr. Appel was named the 2006 Distinguished Researcher by the International Society of Hypertension in Blacks, and he was the 2010 Conner Lecturer at the American Heart Association Scientific Sessions. (
  • For a list of the members of the 2017 ACC/AHA Hypertension Guideline Writing Committee, see the Appendix . (
  • National Conference and Exhibition 2017: AAP Guidelines for Childhood Hypertension Highlights (Video) - An overview of the major changes in the 2017 guidelines, as well as implications for the practitioner. (
  • Hypertension, is called 'the silent killer' as it often asymptomatic. (
  • In the early stages, pulmonary hypertension may be asymptomatic. (
  • Results showed that pregnant women who did not exercise are 3 times more likely to develop hypertension. (
  • [1] Medications specifically used to treat pulmonary hypertension include epoprostenol , treprostinil , iloprost , bosentan , ambrisentan , macitentan , and sildenafil . (
  • Current Hypertension Reports provides in-depth review articles contributed by international experts on the most significant developments in the field. (
  • The scenarios considered include not only cases in which arterial hypertension is truly resistant but also instances of pseudo-resistant hypertension, including cases in which resistance is related to comorbidities, concomitant treatments, or the use of drugs. (
  • BIRMINGHAM, Ala. -- The American Heart Association has issued consensus guidelines for treating resistant hypertension, a common, difficult-to-manage condition. (
  • with hypertension that was resistant to pharmacologic techniques were selected for a surgical study to receive bilateral renal nerve ablation. (
  • Pulmonary hypertension (PULL-mun-ary HI-per-TEN-shun), or PH, is increased pressure in the pulmonary arteries. (
  • No applicant who has palpable arteries or hypertension can be considered a first class risk. (
  • A patient is deemed to have pulmonary hypertension if the pulmonary mean arterial pressure is greater than 25mmHg at rest, or greater than 30mmHg during exercise. (
  • [13] Pulmonary venous hypertension typically presents with shortness of breath while lying flat or sleeping ( orthopnea or paroxysmal nocturnal dyspnea ), while pulmonary arterial hypertension (PAH) typically does not. (
  • People with both a low level of fitness and a parent with hypertension had a 70 percent higher risk for developing hypertension, compared with highly fit people with no parental history, Shook said. (
  • Ethnicity: African Americans seem to be at a higher risk for developing hypertension as compared to other ethnic groups. (
  • In this view the person with essential hypertension is one who happens to inherit an aggregate of genes determining hypertension (and also is exposed to exogenous factors that favor hypertension). (
  • Following organizations serve the condition "Essential hypertension" for support, advocacy or research. (
  • The terms "Essential hypertension" returned 1018 free, full-text research articles on human participants. (
  • Association of angiotensin-converting enzyme 2 gene polymorphism and enzymatic activity with essential hypertension in different gender: A case-control study. (
  • Angiotensin-converting enzyme 2 (ACE2) plays an important role in the development of essential hypertension (EH). (
  • Renal resistive index and aortic knob width relationship as a predictor of renal prognosis in essential hypertension. (
  • These cases are classified as essential hypertension. (
  • The causes of essential hypertension, however, are not well understood. (
  • Essential hypertension is a complex condition with a variety of factors, both genetic and environmental, contributing to its development. (
  • More than 100 genetic variations have been associated with essential hypertension. (
  • While these variations have been found more commonly in people with essential hypertension than in unaffected individuals, none are common causes of the condition. (
  • The most-studied genetic association in essential hypertension is with genes involved in the renin-angiotensin-aldosterone system. (
  • Therefore, if you have ocular hypertension, it is essential to have regular comprehensive optometric examinations. (
  • Essential Hypertension is the most common type. (
  • The hereditary factor may be one reason for essential hypertension. (
  • This is called essential hypertension . (
  • There is mostly essential or obesity-related hypertension. (
  • Messerli FH, Williams B, Ritz E. Essential Hypertension. (
  • Therefore, while evaluating glaucoma risk factors, it is important to keep in mind that people with thinner corneas and ocular hypertension are more susceptible to glaucoma than those with thicker corneas and ocular hypertension. (
  • Hypertension is one of the major risk factors for the development of cardiovascular diseases including stroke and may also have a role in the development of vascular cognitive impairment and vascular dementia [1, 2]. (
  • Systemic hypertension in very low-birth weight infants with bronchopulmonary dysplasia: incidence and risk factors. (
  • Antenatal and postnatal risk factors for neonatal hypertension and infant follow-up. (
  • 2. Literature review This chapter reviews the literature on hypertension and hyperlipidaemia and their relation to risk factors including age, gender, genetics, diet and weight, alcohol, smoking, lack of activity and co-morbidity. (
  • Describe the risk factors for neonatal hypertension. (
  • A new RCT out of India suggests that sea buckthorn seed oil supplementation reduced dyslipidemia, cardiovascular risk factors, and hypertension in a human population. (
  • Our current preventive routine focuses on treating such cardiac risk factors as hypertension and cholesterol. (
  • What are risk factors for hypertension? (
  • BOSTON -- Albumin excretion at the upper end of the normal range significantly increases the risk of hypertension in otherwise low-risk patients, according to new analyses of the Nurses' Health Study. (
  • Ocular hypertension is defined as a higher than normal intraocular pressure (eye pressure) that significantly increases the risk of developing glaucoma. (
  • This is called Malignant Hypertension and could result in stroke, rupture of an aneurysm, and a heart attack. (
  • Several factors that are associated with ocular hypertension can further increase the risk of glaucoma onset. (
  • Some were elderly with underlying conditions like hypertension and diabetes. (
  • At the Hypertension Clinic, located within the Sanford Bemidji Heart and Vascular Center, we provide a risk factor reduction education program addressing: diet, exercise and medical management of comorbidities linked with coronary artery disease, heart attack, stroke, peripheral artery disease, diabetes and renal failure. (
  • NEW YORK -- Hypertension appears to increase the risk of mild cognitive impairment, primarily the nonamnestic form of the disorder in which memory is not significantly affected, researchers here said. (
  • In related work, Baltimore scientists collaborating with researchers from the UpJohn Co. in Kalamazoo, Mich., found that a substance that regulates sodium levels in cells also turns out to be ouabain, which may explain the link between salt consumption and hypertension in some people. (
  • If their findings hold up in future studies, the researchers expect it will change the way doctors treat hypertension. (
  • In another study, researchers studied an Israeli family of Iraqi-Jewish origin whose members suffered from hypertension and renal failure. (
  • For example, researchers observed a family of Old Order Amish in Lancaster, Pennsylvania and found a genetic link for hypertension to chromosome 2q31-34. (
  • The primary objective of the study is to assess the effect of SMS messages on BP control in aboriginal people in Canada and rural Tanzania with hypertension. (
  • Primary pulmonary hypertension. (
  • Primary pulmonary hypertension (PPH) is a progressive disease characterised by raised pulmonary vascular resistance, which results in diminished right-heart function due to increased right ventricular afterload. (
  • Often, but not always, pulmonary hypertension will improve after the congenital heart defect is repaired. (
  • In addition, our clinic has has particular interest in infants with congenital diaphragmatic hernias (CDH) with resulting pulmonary hypertension. (