Hyperplasia. Medical search

An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.

Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both.

Benign proliferation of the ENDOMETRIUM in the UTERUS. Endometrial hyperplasia is classified by its cytology and glandular tissue. There are simple, complex (adenomatous without atypia), and atypical hyperplasia representing also the ascending risk of becoming malignant.

A group of inherited disorders of the ADRENAL GLANDS, caused by enzyme defects in the synthesis of cortisol (HYDROCORTISONE) and/or ALDOSTERONE leading to accumulation of precursors for ANDROGENS. Depending on the hormone imbalance, congenital adrenal hyperplasia can be classified as salt-wasting, hypertensive, virilizing, or feminizing. Defects in STEROID 21-HYDROXYLASE; STEROID 11-BETA-HYDROXYLASE; STEROID 17-ALPHA-HYDROXYLASE; 3-beta-hydroxysteroid dehydrogenase (3-HYDROXYSTEROID DEHYDROGENASES); TESTOSTERONE 5-ALPHA-REDUCTASE; or steroidogenic acute regulatory protein; among others, underlie these disorders.

Non-inflammatory enlargement of the gingivae produced by factors other than local irritation. It is characteristically due to an increase in the number of cells. (From Jablonski's Dictionary of Dentistry, 1992, p400)

Enlargement of the thymus. A condition described in the late 1940's and 1950's as pathological thymic hypertrophy was status thymolymphaticus and was treated with radiotherapy. Unnecessary removal of the thymus was also practiced. It later became apparent that the thymus undergoes normal physiological hypertrophy, reaching a maximum at puberty and involuting thereafter. The concept of status thymolymphaticus has been abandoned. Thymus hyperplasia is present in two thirds of all patients with myasthenia gravis. (From Segen, Dictionary of Modern Medicine, 1992; Cecil Textbook of Medicine, 19th ed, p1486)

Solitary or multiple benign hepatic vascular tumors, usually occurring in women of 20-50 years of age. The nodule, poorly encapsulated, consists of a central stellate fibrous scar and normal liver elements such as HEPATOCYTES, small BILE DUCTS, and KUPFFER CELLS among the intervening fibrous septa. The pale colored central scar represents large blood vessels with hyperplastic fibromuscular layer and narrowing lumen.

The innermost layer of an artery or vein, made up of one layer of endothelial cells and supported by an internal elastic lamina.

Hyperplasia of the mucous membrane of the lips, tongue, and less commonly, the buccal mucosa, floor of the mouth, and palate, presenting soft, painless, round to oval sessile papules about 1 to 4 mm in diameter. The condition usually occurs in children and young adults and has familial predilection, lasting for several months, sometimes years, before running its course. A viral etiology is suspected, the isolated organism being usually the human papillomavirus. (Jablonski, Illustrated Dictionary of Dentistry; Belshe, Textbook of Human Virology, 2d ed, p954)

The new and thickened layer of scar tissue that forms on a PROSTHESIS, or as a result of vessel injury especially following ANGIOPLASTY or stent placement.

Solitary or multiple benign cutaneous nodules comprised of immature and mature vascular structures intermingled with endothelial cells and a varied infiltrate of eosinophils, histiocytes, lymphocytes, and mast cells.

An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP21 gene, converts progesterones to precursors of adrenal steroid hormones (CORTICOSTERONE; HYDROCORTISONE). Defects in CYP21 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).

Pathological processes that tend eventually to become malignant. (From Dorland, 27th ed)

A group of disorders having a benign course but exhibiting clinical and histological features suggestive of malignant lymphoma. Pseudolymphoma is characterized by a benign infiltration of lymphoid cells or histiocytes which microscopically resembles a malignant lymphoma. (From Dorland, 28th ed & Stedman, 26th ed)

A gland in males that surrounds the neck of the URINARY BLADDER and the URETHRA. It secretes a substance that liquefies coagulated semen. It is situated in the pelvic cavity behind the lower part of the PUBIC SYMPHYSIS, above the deep layer of the triangular ligament, and rests upon the RECTUM.

Two pairs of small oval-shaped glands located in the front and the base of the NECK and adjacent to the two lobes of THYROID GLAND. They secrete PARATHYROID HORMONE that regulates the balance of CALCIUM; PHOSPHORUS; and MAGNESIUM in the body.

Histochemical localization of immunoreactive substances using labeled antibodies as reagents.

Tumors or cancer of ENDOMETRIUM, the mucous lining of the UTERUS. These neoplasms can be benign or malignant. Their classification and grading are based on the various cell types and the percent of undifferentiated cells.

Removal of all or part of the PROSTATE, often using a cystoscope and/or resectoscope passed through the URETHRA.

Damages to the CAROTID ARTERIES caused either by blunt force or penetrating trauma, such as CRANIOCEREBRAL TRAUMA; THORACIC INJURIES; and NECK INJURIES. Damaged carotid arteries can lead to CAROTID ARTERY THROMBOSIS; CAROTID-CAVERNOUS SINUS FISTULA; pseudoaneurysm formation; and INTERNAL CAROTID ARTERY DISSECTION. (From Am J Forensic Med Pathol 1997, 18:251; J Trauma 1994, 37:473)

A benign epithelial tumor with a glandular organization.

A metabolite of PROGESTERONE with a hydroxyl group at the 17-alpha position. It serves as an intermediate in the biosynthesis of HYDROCORTISONE and GONADAL STEROID HORMONES.

Obstruction of flow in biological or prosthetic vascular grafts.

Veins in the neck which drain the brain, face, and neck into the brachiocephalic or subclavian veins.

A glandular epithelial cell or a unicellular gland. Goblet cells secrete MUCUS. They are scattered in the epithelial linings of many organs, especially the SMALL INTESTINE and the RESPIRATORY TRACT.

Large benign, hyperplastic lymph nodes. The more common hyaline vascular subtype is characterized by small hyaline vascular follicles and interfollicular capillary proliferations. Plasma cells are often present and represent another subtype with the plasma cells containing IgM and IMMUNOGLOBULIN A.

Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.

Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.

Pathological processes of the PARATHYROID GLANDS. They usually manifest as hypersecretion or hyposecretion of PARATHYROID HORMONE that regulates the balance of CALCIUM; PHOSPHORUS; and MAGNESIUM in the body.

Excess production of ADRENAL CORTEX HORMONES such as ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and/or ANDROSTENEDIONE. Hyperadrenal syndromes include CUSHING SYNDROME; HYPERALDOSTERONISM; and VIRILISM.

Drugs that inhibit 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE. They are commonly used to reduce the production of DIHYDROTESTOSTERONE.

The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.

The nonstriated involuntary muscle tissue of blood vessels.

All of the processes involved in increasing CELL NUMBER including CELL DIVISION.

General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).

Homopolymer of tetrafluoroethylene. Nonflammable, tough, inert plastic tubing or sheeting; used to line vessels, insulate, protect or lubricate apparatus; also as filter, coating for surgical implants or as prosthetic material. Synonyms: Fluoroflex; Fluoroplast; Ftoroplast; Halon; Polyfene; PTFE; Tetron.

A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)

The measurement of an organ in volume, mass, or heaviness.

Tumors or cancer of the PARATHYROID GLANDS.

Surgical insertion of BLOOD VESSEL PROSTHESES, or transplanted BLOOD VESSELS, or other biological material to repair injured or diseased blood vessels.

A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.

Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.

A pair of glands located at the cranial pole of each of the two KIDNEYS. Each adrenal gland is composed of two distinct endocrine tissues with separate embryonic origins, the ADRENAL CORTEX producing STEROIDS and the ADRENAL MEDULLA producing NEUROTRANSMITTERS.

A plant genus in the family ARECACEAE, order Arecales, subclass Arecidae. The fruit or the extract (Permixon) is used for PROSTATIC HYPERPLASIA.

Pathological processes of the BREAST.

An orally active 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE inhibitor. It is used as a surgical alternative for treatment of benign PROSTATIC HYPERPLASIA.

Tumors or cancer of the PROSTATE.

The external, nonvascular layer of the skin. It is made up, from within outward, of five layers of EPITHELIUM: (1) basal layer (stratum basale epidermidis); (2) spinous layer (stratum spinosum epidermidis); (3) granular layer (stratum granulosum epidermidis); (4) clear layer (stratum lucidum epidermidis); and (5) horny layer (stratum corneum epidermidis).

Pathological processes of the ADRENAL GLANDS.

A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane.

Non-striated, elongated, spindle-shaped cells found lining the digestive tract, uterus, and blood vessels. They are derived from specialized myoblasts (MYOBLASTS, SMOOTH MUSCLE).

The vessels carrying blood away from the capillary beds.

The mucous membrane lining of the uterine cavity that is hormonally responsive during the MENSTRUAL CYCLE and PREGNANCY. The endometrium undergoes cyclic changes that characterize MENSTRUATION. After successful FERTILIZATION, it serves to sustain the developing embryo.

Use of a balloon catheter for dilation of an occluded artery. It is used in treatment of arterial occlusive diseases, including renal artery stenosis and arterial occlusions in the leg. For the specific technique of BALLOON DILATION in coronary arteries, ANGIOPLASTY, BALLOON, CORONARY is available.

Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.

Steroidal compounds in which one or more carbon atoms in the steroid ring system have been substituted with nitrogen atoms.

Nuclear antigen with a role in DNA synthesis, DNA repair, and cell cycle progression. PCNA is required for the coordinated synthesis of both leading and lagging strands at the replication fork during DNA replication. PCNA expression correlates with the proliferation activity of several malignant and non-malignant cell types.

Elements of limited time intervals, contributing to particular results or situations.

Tests to experimentally measure the tumor-producing/cancer cell-producing potency of an agent by administering the agent (e.g., benzanthracenes) and observing the quantity of tumors or the cell transformation developed over a given period of time. The carcinogenicity value is usually measured as milligrams of agent administered per tumor developed. Though this test differs from the DNA-repair and bacterial microsome MUTAGENICITY TESTS, researchers often attempt to correlate the finding of carcinogenicity values and mutagenicity values.

MAMMARY GLANDS in the non-human MAMMALS.

Either of two large arteries originating from the abdominal aorta; they supply blood to the pelvis, abdominal wall and legs.

One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.

A condition of abnormally elevated output of PARATHYROID HORMONE (or PTH) triggering responses that increase blood CALCIUM. It is characterized by HYPERCALCEMIA and BONE RESORPTION, eventually leading to bone diseases. PRIMARY HYPERPARATHYROIDISM is caused by parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. SECONDARY HYPERPARATHYROIDISM is increased PTH secretion in response to HYPOCALCEMIA, usually caused by chronic KIDNEY DISEASES.

In humans, one of the paired regions in the anterior portion of the THORAX. The breasts consist of the MAMMARY GLANDS, the SKIN, the MUSCLES, the ADIPOSE TISSUE, and the CONNECTIVE TISSUES.

Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.

A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.

A benign epithelial tumor of the LIVER.

Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.

A common and benign breast disease characterized by varying degree of fibrocystic changes in the breast tissue. There are three major patterns of morphological changes, including FIBROSIS, formation of CYSTS, and proliferation of glandular tissue (adenosis). The fibrocystic breast has a dense irregular, lumpy, bumpy consistency.

Tumors or cancers of the ADRENAL CORTEX.

A condition in which there is a change of one adult cell type to another similar adult cell type.

A neoplastic disease in which the alveoli and distal bronchi are filled with mucus and mucus-secreting columnar epithelial cells. It is characterized by abundant, extremely tenacious sputum, chills, fever, cough, dyspnea, and pleuritic pain. (Stedman, 25th ed)

The main artery of the thigh, a continuation of the external iliac artery.

Blocked urine flow through the bladder neck, the narrow internal urethral opening at the base of the URINARY BLADDER. Narrowing or strictures of the URETHRA can be congenital or acquired. It is often observed in males with enlarged PROSTATE glands.

Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.

A malignant epithelial tumor with a glandular organization.

Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.

A subtype of enteroendocrine cells found in the gastrointestinal MUCOSA, particularly in the glands of PYLORIC ANTRUM; DUODENUM; and ILEUM. These cells secrete mainly SEROTONIN and some neuropeptides. Their secretory granules stain readily with silver (argentaffin stain).

The two principal arteries supplying the structures of the head and neck. They ascend in the neck, one on each side, and at the level of the upper border of the thyroid cartilage, each divides into two branches, the external (CAROTID ARTERY, EXTERNAL) and internal (CAROTID ARTERY, INTERNAL) carotid arteries.

A metabolite of 17-ALPHA-HYDROXYPROGESTERONE, normally produced in small quantities by the GONADS and the ADRENAL GLANDS, found in URINE. An elevated urinary pregnanetriol is associated with CONGENITAL ADRENAL HYPERPLASIA with a deficiency of STEROID 21-HYDROXYLASE.

An anterior pituitary hormone that stimulates the ADRENAL CORTEX and its production of CORTICOSTEROIDS. ACTH is a 39-amino acid polypeptide of which the N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Upon further tissue-specific processing, ACTH can yield ALPHA-MSH and corticotrophin-like intermediate lobe peptide (CLIP).

Discrete abnormal tissue masses that protrude into the lumen of the DIGESTIVE TRACT or the RESPIRATORY TRACT. Polyps can be spheroidal, hemispheroidal, or irregular mound-shaped structures attached to the MUCOUS MEMBRANE of the lumen wall either by a stalk, pedunculus, or by a broad base.

The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.

Pathological processes involving the PROSTATE or its component tissues.

The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.

A condition caused by the overproduction of ALDOSTERONE. It is characterized by sodium retention and potassium excretion with resultant HYPERTENSION and HYPOKALEMIA.

Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.

Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels.

The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.

Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.

A synthetic mineralocorticoid with anti-inflammatory activity.

RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.

Metabolites or derivatives of PROGESTERONE with hydroxyl group substitution at various sites.

Infiltration of inflammatory cells into the parenchyma of PROSTATE. The subtypes are classified by their varied laboratory analysis, clinical presentation and response to treatment.

Immunologic techniques based on the use of: (1) enzyme-antibody conjugates; (2) enzyme-antigen conjugates; (3) antienzyme antibody followed by its homologous enzyme; or (4) enzyme-antienzyme complexes. These are used histologically for visualizing or labeling tissue specimens.

Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.

Surgical shunt allowing direct passage of blood from an artery to a vein. (From Dorland, 28th ed)

Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

A noninvasive (noninfiltrating) carcinoma of the breast characterized by a proliferation of malignant epithelial cells confined to the mammary ducts or lobules, without light-microscopy evidence of invasion through the basement membrane into the surrounding stroma.

Pathological processes of the ADRENAL CORTEX.

Non-human animals, selected because of specific characteristics, for use in experimental research, teaching, or testing.

Diseases of LYMPH; LYMPH NODES; or LYMPHATIC VESSELS.

Removal and examination of tissue obtained through a transdermal needle inserted into the specific region, organ, or tissue being analyzed.

A species of gram-negative bacteria in the genus CITROBACTER, family ENTEROBACTERIACEAE. As an important pathogen of laboratory mice, it serves as a model for investigating epithelial hyperproliferation and tumor promotion. It was previously considered a strain of CITROBACTER FREUNDII.

A condition with multiple tumor-like lesions caused either by congenital or developmental malformations of BLOOD VESSELS, or reactive vascular proliferations, such as in bacillary angiomatosis. Angiomatosis is considered non-neoplastic.

Abnormally elevated PARATHYROID HORMONE secretion as a response to HYPOCALCEMIA. It is caused by chronic KIDNEY FAILURE or other abnormalities in the controls of bone and mineral metabolism, leading to various BONE DISEASES, such as RENAL OSTEODYSTROPHY.

Symptoms of disorders of the lower urinary tract including frequency, NOCTURIA; urgency, incomplete voiding, and URINARY INCONTINENCE. They are often associated with OVERACTIVE BLADDER; URINARY INCOMPETENCE; and INTERSTITIAL CYSTITIS. Lower urinary tract symptoms in males were traditionally called PROSTATISM.

The condition of an anatomical structure's being constricted beyond normal dimensions.

A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.

Tumors or cancer of the ADRENAL GLANDS.

The epizootiology and pathogenesis of thyroid hyperplasia in coho salmon (Oncorhynchus kisutch) in Lake Ontario. (1/4620)

The thyroid glands of coho salmon collected at different stages of their anadromous migration exhibited progressive and extensive hyperplasia and hypertrophy. The incidence of overt nodule formation rose from 5% in fish collected in August to 24% in fish collected in October. The histological picture of the goiters was similar to that found in thiourea-treated teleosts and thiouracil-treated mammals. There was a concomitant, significant decrease in serum thyroxine and triiodothyronine values between September and October (thyroxine, 1.0+/-0.3 mug/100 ml and 0.4 mug/100 ml in September and October, respectively; triiodothyronine, 400.3+/-51.6 ng/100 ml and 80.2 ng/100 ml in September and October, respectively) and marked hypertrophy and hyperplasia of thyrotrophs. These data indicate a progressive hypothyroid condition which, although it may be linked to iodide deficiency, may well be enhanced by other environmental factors. The evidence for involvement of other factors is discussed. (+info)

Natural history of papillary lesions of the urinary bladder in schistosomiasis. (2/4620)

Variable epithelial hyperplasia was observed in urinary bladder of nine capuchin monkeys (Cebus apella) when examined at cystotomy 94 to 164 weeks after infection with Schistosoma haematobium. These hosts were followed for 24 to 136 weeks postcystotomy to determine the status of bladder lesions in relation to duration of infection and to ascertain whether lesion samples removed at cystotomy reestablished themselves in autologous and heterologous transfers. There was involution of urothelial hyperplasia in eight of nine animals and no evidence for establishment of transplanted bladder lesions. (+info)

Ganglioneuromas and renal anomalies are induced by activated RET(MEN2B) in transgenic mice. (3/4620)

Multiple endocrine neoplasia type 2B (MEN2B) is an autosomal dominant syndrome characterized by the development of medullary thyroid carcinoma, pheochromocytomas, musculoskeletal anomalies and mucosal ganglioneuromas. MEN2B is caused by a specific mutation (Met918-->Thr) in the RET receptor tyrosine kinase. Different mutations of RET lead to other conditions including MEN2A, familial medullary thyroid carcinoma and intestinal aganglionosis (Hirschsprung disease). Transgenic mice were created using the dopamine beta-hydroxylase promoter to direct expression of RET(MEN2B) in the developing sympathetic and enteric nervous systems and the adrenal medulla. DbetaH-RET(MEN2B) transgenic mice developed benign neuroglial tumors, histologically identical to human ganglioneuromas, in their sympathetic nervous systems and adrenal glands. The enteric nervous system was not affected. The neoplasms in DbetaH-RET(MEN2B) mice were similar to benign neuroglial tumors induced in transgenic mice by activated Ras expression under control of the same promoter. Levels of phosphorylated MAP kinase were not increased in the RET(MEN2B)-induced neurolglial proliferations, suggesting that alternative pathways may play a role in the pathogenesis of these lesions. Transgenic mice with the highest levels of DbetaH-RET(MEN2B) expression, unexpectedly developed renal malformations analogous to those reported with loss of function mutations in the Ret gene. (+info)

Anti-monocyte chemoattractant protein-1/monocyte chemotactic and activating factor antibody inhibits neointimal hyperplasia in injured rat carotid arteries. (4/4620)

Monocyte chemoattractant protein-1 (MCP-1)/monocyte chemotactic and activating factor (MCAF) has been suggested to promote atherogenesis. The effects of in vivo neutralization of MCP-1 in a rat model were examined in an effort to clarify the role of MCP-1 in the development of neointimal hyperplasia. Competitive polymerase chain reaction analysis revealed maximum MCP-1 mRNA expression at 4 hours after carotid arterial injury. Increased immunoreactivities of MCP-1 were also detected at 2 and 8 hours after injury. Either anti-MCP-1 antibody or nonimmunized goat IgG (10 mg/kg) was then administered every 12 hours to rats that had undergone carotid arterial injury. Treatment with 3 consecutive doses of anti-MCP-1 antibody within 24 hours (experiment 1) and every 12 hours for 5 days (experiment 2) significantly inhibited neointimal hyperplasia at day 14, resulting in a 27.8% reduction of the mean intima/media ratio (P<0.05) in experiment 1 and a 43.6% reduction (P<0.01) in experiment 2. This effect was still apparent at day 56 (55.6% inhibition; P<0.05). The number of vascular smooth muscle cells in the neointima at day 4 was significantly reduced by anti-MCP-1 treatment, demonstrating the important role of MCP-1 in early neointimal lesion formation. However, recombinant MCP-1 did not stimulate chemotaxis of vascular smooth muscle cells in an in vitro migration assay. These results suggest that MCP-1 promotes neointimal hyperplasia in early neointimal lesion formation and that neutralization of MCP-1 before, and immediately after, arterial injury may be effective in preventing restenosis after angioplasty. Further studies are needed to clarify the mechanism underlying the promotion of neointimal hyperplasia by MCP-1. (+info)

Myometrial zonal differentiation and uterine junctional zone hyperplasia in the non-pregnant uterus. (5/4620)

Human non-gravid myometrium differentiates in response to ovarian sex steroids into a subendometrial layer or junctional zone and an outer myometrial layer. Compared to the outer myometrial layer, the junctional zone myocytes are characterized by higher cellular density and lower cytoplasmic-nuclear ratio. These structural differences allow in-vivo visualization of the myometrial zonal anatomy by T2-weighted magnetic resonance (MR) imaging. The human myometrium is also functionally polarized. Video-vaginosonography studies have shown that propagated myometrial contractions in the non-pregnant uterus originate only from the junctional zone and that the frequency and orientation of these contraction waves are dependent on the phase of the menstrual cycle. The mechanisms underlying zonal myometrial differentiation are not known, but growing evidence suggests that ovarian hormone action may be mediated through cytokines and uterotonins locally released by the basal endometrial layer and endometrio-myometrial T-lymphocytes. Irregular thickening of the junctional zone due to inordinate proliferation of the inner myometrium, junctional zone hyperplasia, is a common MR finding in women suffering from menstrual dysfunction. Preliminary data suggest that junctional zone hyperplasia is further characterized by loss of normal inner myometrial function. Although irregular thickening of the junctional zone has been associated with diffuse uterine adenomyosis, the precise relationship between subendometrial smooth muscle proliferation and myometrial invasion by endometrial glands and stroma remains to be established. (+info)

Mechanism of parathyroid tumourigenesis in uraemia. (6/4620)

Clonal analysis has shown that in renal hyperparathyroidism (2-HPT), parathyroid glands initially grow diffusely and polyclonally after which the foci of nodular hyperplasia are transformed to monoclonal neoplasia. There is a great deal of information about genetic abnormalities contributing to the tumourigenesis of parathyroid neoplasia in primary hyperparathyroidism. It is speculated that allelic loss of the MEN1 suppressor gene and overexpression of cyclin D1 induced by rearrangement of the parathyroid hormone gene may be the major genetic abnormality in sporadic parathyroid adenoma but not in 2-HPT. The pathogenesis of 2-HPT, abnormality of the Ca2+-sensing receptor (CaR) gene and the vitamin D receptor gene may possibly contribute to parathyroid tumourigenesis in 2-HPT. However, this is not yet clear and heterogeneous and multiple genetic abnormalities may be responsible for the progression of secondary parathyroid hyperplasia. (+info)

Accelerated intimal hyperplasia and increased endogenous inhibitors for NO synthesis in rabbits with alloxan-induced hyperglycaemia. (7/4620)

1. We examined whether endogenous inhibitors of NO synthesis are involved in the augmentation of intimal hyperplasia in rabbits with hyperglycaemia induced by alloxan. 2. Four weeks after the endothelial denudation of carotid artery which had been performed 12 weeks after alloxan, the intimal hyperplasia was greatly augmented with hyperglycaemia. The degree of hyperplasia was assessed using three different parameters of histopathological findings as well as changes in luminal area and intima: media ratio. 3. There were positive and significant correlations between intima:media ratio, plasma glucose, and concentrations of N(G)-monomethyl-L-arginine (L-NMMA) and N(G), N(G)-dimethyl-L-arginine (ADMA) in endothelial cells, that is, the intima:media ratio became greater as plasma glucose and endothelial L-NMMA and ADMA were increased. Furthermore, endothelial L-NMMA and ADMA were increased in proportion to the increase in plasma glucose. 4. In contrast, there were inverse and significant correlations between cyclic GMP production by carotid artery strips with endothelium and plasma glucose, between cyclic GMP production and endothelial L-NMMA and ADMA, and between the intima:media ratio and cyclic GMP production. 5. Exogenously applied L-NMMA and ADMA inhibited cyclic GMP production in a concentration-dependent manner. IC50 values were determined to be 12.1 microM for the former and 26.2 microM for the latter. The cyclic GMP production was abolished after the deliberate removal of endothelium from the artery strips. 6. These results suggest that the augmentation of intimal hyperplasia with hyperglycaemia is closely related to increased accumulation of L-NMMA and ADMA with hyperglycaemia, which would result in an accelerated reduction in NO production/release by endothelial cells. (+info)

Expression of relaxin-like factor is down-regulated in human testicular Leydig cell neoplasia. (8/4620)

In addition to their role in steroidogenesis in the male, testicular Leydig cells constitutively express large amounts of the peptide relaxin-like factor (RLF), also known as Ley-IL. The Leydig cell-derived RLF belongs to the insulin-like superfamily, which also includes relaxin, insulin and the insulin-like growth factors, and within the testis is a specific marker of Leydig cells. Little information is available either on the regulation of gene expression or on the function of this Leydig cell-derived peptide. In the present study we have investigated the expression pattern of human RLF in patients with rare Leydig cell hyperplasia and adenoma. The expression of both mRNA and protein appear to be decreased in hyperplastic Leydig cells, whereas in the Leydig cell adenomas studied, large central areas of the adenoma were devoid of RLF mRNA and protein. Only Leydig cells located at the periphery of the adenoma displayed expression of RLF, with full agreement between in-situ hybridization and immunohistochemistry. It thus appears that the expression of the RLF gene and its products are down-regulated in Leydig cell hyperplasia and adenoma, consistent with a concomitant dedifferentiation of these cells. (+info)

What Are the Signs & Symptoms of Congenital Adrenal Hyperplasia? (kidshealth.org)
What Causes Congenital Adrenal Hyperplasia? (kidshealth.org)
Who Gets Congenital Adrenal Hyperplasia? (kidshealth.org)
How Is Congenital Adrenal Hyperplasia Diagnosed? (kidshealth.org)
How Is Congenital Adrenal Hyperplasia Treated? (kidshealth.org)
Neurocrine Biosciences, Inc. announced today that NBI-77860, a proprietary corticotropin releasing factor 1 (CRF) receptor antagonist, has been granted orphan drug status by the United States Food and Drug Administration (FDA) for the treatment of congenital adrenal hyperplasia (CAH) a disease that affects approximately 20,000-30,000 people in the United States. (news-medical.net)
Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders caused by deficiency in one or more of the enzymes required for adrenal gland synthesis of cortisol, aldosterone, and the sex steroids. (questdiagnostics.com)
A mutation or deletion of any of the genes that code for enzymes involved in cortisol or aldosterone synthesis results in congenital adrenal hyperplasia. (medscape.com)
Congenital adrenal hyperplasia (CAH) is a form of adrenal insufficiency in which 21-hydroxylase, the enzyme that produces two important adrenal steroid hormones, cortisol and aldosterone, is deficient. (yourdictionary.com)
Congenital adrenal hyperplasia (CAH) is a genetic disorder characterized by a deficiency in the hormones cortisol and aldosterone and an over-production of the hormone androgen. (yourdictionary.com)
Congenital adrenal hyperplasia: lessons from a multinational study. (nih.gov)
A study group of paediatric endocrinologists was established in Austria, Czech Republic, Hungary, Slovenia and Slovakia in order to investigate various aspects in children with congenital adrenal hyperplasia (CAH). (nih.gov)
Congenital adrenal hyperplasia - Inherited disorder of gland (adrenal). (wikipedia.org)
Congenital Adrenal Hyperplasia: A Comprehensive Guide addresses how hydrocortisone works, what can go wrong, and how to correct it, also explaining why the timing of doses and measurement of cortisol from a dose is extremely important. (waterstones.com)
Individuals with congenital adrenal hyperplasia (CAH) require glucocorticoid therapy to replace cortisol and to control androgen excess. (medpagetoday.com)
Congenital Adrenal Hyperplasia (CAH) is a medical condition that has different types. (umich.edu)
Congenital adrenal hyperplasia ( CAH ) refers to any of several autosomal recessive conditions resulting from biochemical paths of the steroidogenesis of cortisol from cholesterol by the adrenal glands . (bionity.com)
The defects causing adrenal hyperplasia are congenital (i.e., present at birth). (bionity.com)
In all its forms, congenital adrenal hyperplasia due to 21-hydroxylase deficiency accounts for about 95% of diagnosed cases of CAH. (bionity.com)
Late-onset adrenal hyperplasia refers to a congenital endocrine disorder, associated with an enlargement of the adrenal glands, which causes increased aldosterone production and an insufficiency of cortisol. (wisegeek.com)
Congenital adrenal hyperplasia occurs when a genetic mutation causes the deficiency of an enzyme called 21-hydroxylase. (wisegeek.com)
Pseudohypoaldosteronism Masquerading as Congenital Adrenal Hyperplasia. (biomedsearch.com)
A 15-day- old male infant presented with features suggestive of congenital adrenal hyperplasia (CAH). (biomedsearch.com)
The Congenital Adrenal Hyperplasia Trust (New Zealand) (CAHNZ Trust) is a registered trust located in New Zealand. (rarediseases.org)
Founded in 1996, CAHNZ Trust provides support and information to New Zealanders affected by congenital adrenal hyperplasia (CAH). (rarediseases.org)

With atypical ductal hyperplasia (ADH), there are more cells than usual in the lining of the breast duct, the tube that carries milk from the lobules (milk sacs) to the nipple. (breastcancer.org)
Atypical ductal hyperplasia is an increase in abnormal cells growing in the breast ducts. (cancer.ca)
Hyperplasia of the breast - 'Hyperplastic' lesions of the breast include usual ductal hyperplasia , a focal expansion of the number of cells in a terminal breast duct, and atypical ductal hyperplasia , in which a more abnormal pattern of growth is seen, and which is associated with an increased risk of developing breast cancer. (bionity.com)
Despite this unusual appearance, the extra cells in atypical ductal hyperplasia are still dividing in a controlled way. (cancervic.org.au)
Women with a diagnosis of atypical ductal hyperplasia may think about taking hormone replacement therapy (HRT) if they're troubled by symptoms arising from menopause. (cancervic.org.au)
Atypical ductal hyperplasia (ADH) is not a form of breast cancer. (hopkinsmedicine.org)
If you have a biopsy that shows atypical ductal hyperplasia in one of your breasts, your doctor will want to follow your breast health very carefully. (hopkinsmedicine.org)
How is a diagnosis made for atypical ductal hyperplasia? (hopkinsmedicine.org)
After a core breast biopsy , an analysis will confirm the presence of atypical ductal hyperplasia cells in the breast tissue. (hopkinsmedicine.org)
What can I do if I'm diagnosed with atypical ductal hyperplasia? (hopkinsmedicine.org)
If the pathology findings are limited to atypical ductal hyperplasia, you do not have breast cancer - but you do have an increased risk of developing it in the future. (hopkinsmedicine.org)
It is believed that atypical ductal hyperplasia (ADH) is a direct precursor for low-grade mammary ductal carcinoma, whereas atypical lobular hyperplasia (ALH) serves as a risk indicator. (wikipedia.org)
Long term clinical follow-up of atypical ductal hyperplasia and lobular carcinoma in situ in breast core needle biopsies. (thefreedictionary.com)
Ductal hyperplasia without atypia, atypical ductal hyperplasia , intraductal hyperplasia with atypia, and ductal papillomatosis were the proliferative lesions. (thefreedictionary.com)
Rates of atypical ductal hyperplasia declined with less use of postmenopausal hormone treatment: findings from the Breast Cancer Surveillance Consortium. (thefreedictionary.com)
Previous studies have shown that women who are diagnosed with atypical ductal hyperplasia are at a three- to five-fold increased risk of developing breast cancer. (thefreedictionary.com)
Only about 60% of the breast cancers that develop in women with either atypical lobular hyperplasia or atypical ductal hyperplasia occur in the ipsilateral breast. (thefreedictionary.com)
Additional objectives included determining the incidence of significant pathologic findings (SPF), defined as occult carcinoma and atypical hyperplasia (including atypical ductal hyperplasia [ADH] and atypical lobular hyperplasia [ALH]), in RMP specimens. (thefreedictionary.com)
ADH-5 can solve multiple clinical problems including 1) differentiating hyperplasia of the usual type from atypical ductal hyperplasia , 2) identifying microinvasion and invasive ductal carcinoma, and 3) distinguishing basal phenotypes on triple negatives. (thefreedictionary.com)
Atypical ductal hyperplasia (ADH), lobular carcinoma in situ (LCIS) and atypical lobular hyperplasia (ALH) may also present with calcifications that may exhibit high density, clustered punctuate calcification and tending to lack the characteristic features of DCIS such as rod shapes, ductal distribution and branching. (thefreedictionary.com)

Benign prostatic hyperplasia symptoms are classified as storage or voiding. (princeton.edu)
What are signs and symptoms of endometrial hyperplasia? (acog.org)
People react in their own way to the symptoms of benign prostatic hyperplasia ( BPH ), a common condition for men as they age. (webmd.com)
Benign prostatic hyperplasia (BPH) is an age-related, nonmalignant condition that may lead to bothersome lower urinary tract symptoms. (springer.com)
In view of a normal ultrasound, the absence of any symptoms, and after review of the previously reported slides we regarded this case as endometrial stromal hyperplasia. (hindawi.com)
Re: A Prospective Randomised Placebo-Controlled Study of the Impact of Dutasteride/Tamsulosin Combination Therapy on Sexual Function Domains in Sexually Active Men with Lower Urinary Tract Symptoms (LUTS) Secondary to Benign Prostatic Hyperplasia (BPH). (tripdatabase.com)
Active Men with Lower Urinary Tract Symptoms (LUTS) Secondary to Benign Prostatic Hyperplasia (BPH). (tripdatabase.com)
Erratum: Efficacy of tamsulosin and tadalafil in relieving benign prostatic hyperplasia related symptoms: A randomized double blind placebo controlled cross-over study. (tripdatabase.com)
Re: rezÅ«m Water Vapor Thermal Therapy for Lower Urinary Tract Symptoms Associated with Benign Prostatic Hyperplasia: 4-Year Results from Randomized Controlled Study. (tripdatabase.com)
Influence of alpha-adrenoceptor antagonists therapy on stool form in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia. (tripdatabase.com)
Symptoms related to benign prostatic hyperplasia (BPH) are the most common reason why patients consult a urologist. (urotoday.com)
Benign prostatic hyperplasia (BPH) impacts quality of life in men by causing lower urinary tract symptoms. (urotoday.com)
Benign prostatic hyperplasia (BPH) is a term that refers to an enlargement of the prostate gland in older men, a condition that can cause a variety of urinary tract symptoms. (uspharmacist.com)
Atypical hyperplasia of the breast does not cause any symptoms. (cancer.ca)
Benign prostatic hyperplasia (BPH) is a nonmalignant enlargement of the prostate, which can lead to obstructive and irritative lower urinary tract symptoms (LUTS). (nih.gov)
In this study, researchers from Austria, Germany and Switzerland investigated the effects of a proprietary oil-free hydroethanolic pumpkin seed extract on the symptoms of benign prostatic hyperplasia (BPH). (medworm.com)
Natural News) Men who are suffering from a condition called benign prostatic hyperplasia (BPH) or enlarged prostate may find relief from their symptoms with the humble pumpkin seed, according to a study published in the Journal of Medicinal Food. (medworm.com)
Interactive Tool: How Bad Are Your Urinary Symptoms From Benign Prostatic Hyperplasia (BPH)? (northshore.org)
Many men with benign prostatic hyperplasia (BPH) have no symptoms. (northshore.org)
Flomax ( tamsulosin hydrochloride) and Cardura ( doxazosin ) are alpha-blockers used to treat the symptoms of a prostate gland condition called benign prostatic hyperplasia ( BPH , a noncancerous enlargement of the prostate gland ). (rxlist.com)
Cardura (doxazosin) is an alpha-1 adrenergic blocker prescribed for treating high blood pressure , and symptoms associated with benign prostatic hyperplasia (BPH, a noncancerous enlargement of the prostate gland). (rxlist.com)
Late-onset adrenal hyperplasia, or non-classical adrenal hyperplasia (NCAH), can produce symptoms after infancy or when an individual reaches prepubescence. (wisegeek.com)
Late-onset adrenal hyperplasia might not produce life-threatening symptoms, but adrenal crisis is a possibility. (wisegeek.com)
Children having late-onset adrenal hyperplasia may develop visible symptoms as early as the age of two, and physical maturity can appear five years ahead of chronological age with increased bone and muscle growth occurring in both boys and girls. (wisegeek.com)
The most common symptoms of hyperplasia are lumps on the breast, although these lumps do not necessarily indicate hyperplasia (or, for that matter, breast cancer). (floridahospital.com)
Even if there are no symptoms, however, hyperplasia may show up during a routine breast exam or mammogram. (floridahospital.com)

Benign prostatic hyperplasia ( BPH ), also called prostate enlargement , is a noncancerous increase in size of the prostate . (wikipedia.org)
Benign prostatic hyperplasia , also known as prostate enlargement. (wikipedia.org)
Benign prostatic hyperplasia ( BPH ) also known as benign prostatic hypertrophy (technically a misnomer), benign enlargement of the prostate (BEP) , and adenofibromyomatous hyperplasia , refers to the increase in size of the prostate in elderly men. (princeton.edu)
This episode discusses issues related to BPH, benign prostatic hyperplasia (or hypertrophy). (merlot.org)
You just viewed BPH: Benign Prostatic Hyperplasia . (merlot.org)
If you know the author of BPH: Benign Prostatic Hyperplasia , please help us out by filling out the form below and clicking Send. (merlot.org)
Benign prostatic hyperplasia refers to a condition in which the prostate enlarges. (medicalnewstoday.com)
Benign prostatic hyperplasia (BPH) is different from prostate cancer . (medicalnewstoday.com)
MADRID - Prostate artery embolization appears to be a safe and effective alternative to more traditional treatments for benign prostatic hyperplasia , according to two new studies. (medscape.com)
Both studies show "that prostate artery embolization is effective, in terms of both subjective and objective outcomes, as a treatment option in benign prostatic hyperplasia. (medscape.com)
Men with benign prostatic hyperplasia (BPH), a condition in which the prostate is enlarged but not cancerous, have a new, breakthrough treatment option that is less invasive and has fewer complications than other minimally invasive treatments, such as transurethral resection of the prostate and surgical options, according to research presented at the Society of Interventional Radiology's Annual Scientific Meeting. (news-medical.net)
EDITOR-Kirby's editorial on benign prostatic hyperplasia presented a simplistic view of medical treatment for suspected benign prostatic obstruction. (bmj.com)
Benign prostatic hyperplasia is a specific histological term often misused in general parlance. (bmj.com)
The importance of distinguishing between benign prostatic hyperplasia and benign prostatic enlargement and bladder outlet obstruction is fundamental. (bmj.com)
Benign prostatic hyperplasia (BPH) is a result of urogenital aging. (selfgrowth.com)
Benign prostatic hyperplasia (BPH) is an extremely common disease of older men, occurring in more than 70 percent of men over the age of 60. (bcm.edu)
A major factor in the pathogenesis of prostatic hyperplasia is the continuing growth of the transition zone of the prostate due to both epithelial and stromal proliferation. (bcm.edu)
Interleukin-8 expression is increased in senescent prostatic epithelial cells and promotes the development of benign prostatic hyperplasia. (bcm.edu)
Cellular senescence in the pathogenesis of benign prostatic hyperplasia. (bcm.edu)
IL-8 is a paracrine inducer of FGF2, a stromal and epithelial growth factor in benign prostatic hyperplasia. (bcm.edu)
Il-1α is a paracrine inducer of FGF-7, a key epithelial growth factor in benign prostatic hyperplasia. (bcm.edu)
FGF7 and FGF2 are increased in benign prostatic hyperplasia and are associated with increased proliferation. (bcm.edu)
The Benign Prostatic Hyperplasia (BPH) Devices market is expected to rise owing to an increasing prevalence of benign prostatic hyperplasia and growing geriatric population globally. (globenewswire.com)
DelveInsight's Benign Prostatic Hyperplasia (BPH) Devices Market Insights, Competitive Landscape and Market Forecast -2026 provides the current and forecast market of the Benign Prostatic Hyperplasia (BPH) Devices and comprises of market trends and key competitors of Benign Prostatic Hyperplasia (BPH) Devices. (globenewswire.com)
Benign prostatic hyperplasia also called the enlarged prostate or prostate gland enlargement is a very common disorder that is observed in older men. (globenewswire.com)
In the year 2018 , the total eligible patient population for benign prostatic hyperplasia in seven major markets was 7,92,10,572 in 2018 and is expected to increase by 2026. (globenewswire.com)
iTind device (Olympus Corporation), Butterfly Medical Device (Butterfly Medical), and UroLift System (Teleflex Incorporated) are some of the key market players in the Benign Prostatic Hyperplasia Devices market. (globenewswire.com)
COVID-19 impacted the Benign Prostatic Hyperplasia Devices market heavily in 2020 because BPH was positioned as one of the lowest priorities of non-oncological procedures. (globenewswire.com)
On January 27, 2021, Medeon Biodesign Inc. had announced positive clinical trial results for the XFLO minimally invasive Benign Prostatic Hyperplasia treatment device . (globenewswire.com)
On April 6, 2020, the FDA had granted the de novo classification for the iTind device to treat patients suffering from Benign Prostatic Hyperplasia. (globenewswire.com)
Complications of the holmium laser enucleation of prostate for benign prostatic hyperplasia]. (urotoday.com)
Some authors consider HoLEP a new gold standard for the surgical management of prostatic hyperplasia. (urotoday.com)
The risk of bladder cancer in patients with prostatic hyperplasia and strategies to manage this combination]. (urotoday.com)
The combination of bladder cancer with benign prostatic hyperplasia (BPH) occurs in 5-27% of cases. (urotoday.com)
The thulium laser is the most recently introduced technology for the surgical treatment of benign prostatic hyperplasia (BPH). (urotoday.com)
The etiology of benign prostatic hyperplasia (BPH) is multifactorial, and chronic inflammation plays a pivotal role in its pathogenesis. (urotoday.com)
Benign prostatic hyperplasia (BPH) is characterized by the occurrence of.disorders of urine storage and bladder emptying. (aerzteblatt.de)
Benign prostatic hyperplasia (BPH) is an enlarged prostate gland. (healthlinkbc.ca)
Benign prostatic hyperplasia (BPH) is also called benign prostatic hypertrophy. (uhhospitals.org)
Diagnosing benign prostatic hyperplasia (BPH) in its earlier stages can lower the risk of complications. (uhhospitals.org)
3+1' bladder function restoration combined with holmium laser enucleation of the prostate for benign prostatic hyperplasia with acontractile detrusor]. (urotoday.com)
To investigate the clinical effect of '3+1' bladder function restoration combined with holmium laser enucleation of the prostate (HoLEP) in the treatment of benign prostatic hyperplasia (BPH) with acontractile detrusor (ACD). (urotoday.com)
Age-related androgen deficiency and benign prostatic hyperplasia: how to improve the rehabilitation of patients after transurethral surgery? (urotoday.com)
Age-related androgen deficiency often coexists with benign prostatic hyperplasia (BPH), which requires surgical treatment. (urotoday.com)
Analysis of factors affecting the compliance with medical therapy for benign prostatic hyperplasia]. (urotoday.com)
To investigate factors affecting the compliance of patients with the combination therapy for benign prostatic hyperplasia. (urotoday.com)
Approaches to medical management of patients with high risk of progressing of benign prostatic hyperplasia depending on concomitant erectile dysfunction]. (urotoday.com)
To investigate the efficacy and safety of various medical treatment schemes in the management of patients at high risk of progression of benign prostatic hyperplasia (BPH), depending on concomitant erectile dysfunction (ED). (urotoday.com)
One of the risk factors for LUTS is an infravesical obstruction, which is most often caused by benign prostatic hyperplasia (BPH). (urotoday.com)
Combination therapy for benign prostatic hyperplasia in the light of clinical guidelines]. (urotoday.com)
The article reviews clinical trials on the effectiveness of combination therapy with 5-reductase inhibitors and -blockers in men with benign prostatic hyperplasia (BPH). (urotoday.com)
Surgery in patients with large prostates due to benign prostatic hyperplasia (BPH) results in severe dysuria manifesting as frequent or urgent need to urinate and urinary incontinence. (urotoday.com)
An enlarged prostate (benign prostatic enlargement (BPE) or benign prostatic hyperplasia (BPH)) is common in men after the age of about 50. (bioportfolio.com)
Alembic Pharmaceuticals on Tuesday said it has received final approval from the US health regulator for its generic Silodosin capsules used in treatment of benign prostatic hyperplasia. (medworm.com)
Parsemus Foundation) Physicians from Sapienza University in Rome have published promising results of a small prospective interventional trial using noninvasive pulsed electromagnetic field therapy (PEMF) to treat men suffering from benign prostatic hyperplasia (BPH). (medworm.com)
FDA has granted de novo classification to a non-surgical device for the minimally invasive treatment of Benign Prostatic Hyperplasia (BPH). (medworm.com)
Technavio's analysts forecast the Global Benign Prostatic Hyperplasia Devices Market to grow at a CAGR of 5.05% during the period 2018-2022. (benzinga.com)
The report covers the present scenario and the growth prospects of the benign prostatic hyperplasia devices market. (benzinga.com)
To calculate the market size, the report considers the revenue generated from sales of benign prostatic hyperplasia devices across the globe. (benzinga.com)
Technavio's report, benign prostatic hyperplasia devices market 2018-2022, has been prepared based on an in-depth market analysis with inputs from industry experts. (benzinga.com)
Benign prostatic hyperplasia (BPH), also known as enlarged prostate, is a noncancerous enlargement of the prostate gland that occurs when the cells of the prostate gland multiply. (upmc.com)
Benign prostatic hyperplasia (BPH) is a common type of noncancerous tumor that leads to enlargement of the prostate gland in men. (bidmc.org)
Blood tests to detect prostate-specific antigens (PSA), a protein that can be affected by benign prostatic hyperplasia. (bidmc.org)
Benign prostatic hyperplasia is also known as benign prostatic hypertrophy. (northshore.org)
Benign prostatic hyperplasia is probably a normal part of the aging process in men, caused by changes in hormone balance and in cell growth. (northshore.org)
Benign prostatic hyperplasia (BPH) is probably a normal part of the aging process in men. (northshore.org)
If you're a man and you live long enough, you will almost certainly develop benign prostatic hyperplasia (BPH). (epnet.com)
Doctors call the condition benign prostatic hyperplasia (BPH), or benign prostatic hypertrophy. (acupuncture.com)
The following products are considered to be alternative treatments or natural remedies for Benign Prostatic Hyperplasia. (drugs.com)
However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Benign Prostatic Hyperplasia. (drugs.com)
With growing interest for screening, early detection and newer treatment options for prostate cancer, one may have the impression that benign prostatic hyperplasia (BPH) is a declining academic and clinical topic in our everyday practice. (lww.com)

Missing Boy: What Is Adrenal Hyperplasia? (yahoo.com)
Adrenal hyperplasia is a rare genetic condition that involves the adrenal glands, which lie just above the kidneys. (yahoo.com)
What is Late-Onset Adrenal Hyperplasia? (wisegeek.com)
Despite the abnormal growth spurt, children afflicted with late-onset adrenal hyperplasia usually display stunted height by adulthood when compared with peers. (wisegeek.com)
The hormone disruption associated with late-onset adrenal hyperplasia might also produce severe cystic acne in both genders along with emotional and mental disorders. (wisegeek.com)
Children having late-onset adrenal hyperplasia typically have little or no cortisol present in these blood samples. (wisegeek.com)

Hyperplasia may be a sign of abnormal or precancerous changes. (medlineplus.gov)
The most common sign of hyperplasia is abnormal uterine bleeding. (acog.org)
If you have abnormal bleeding and you are 35 years or older, or if you are younger than 35 years and your abnormal bleeding has not been helped by medication, your health care provider may perform diagnostic tests for endometrial hyperplasia and cancer. (acog.org)
Usual hyperplasia" means there is excessive growth of benign cells in an area of the breast, but the cells don't look abnormal. (breastcancer.org)
The definition of hyperplasia is an abnormal increase in the number of cells in an organ or tissue. (yourdictionary.com)
Endometrial hyperplasia is an abnormal thickening of the uterine lining (endometrium) that causes heavy vaginal bleeding. (cigna.com)
Atypical hyperplasia means that the cells that are increasing in a tissue are abnormal. (cancer.ca)
Atypical lobular hyperplasia is an increase in abnormal cells growing in the groups of glands that make milk (called the lobules). (cancer.ca)
In atypical hyperplasia, the proliferating (dividing) cells look abnormal. (komen.org)
It remains uncertain whether there is any difference between metformin and megestrol acetate in reducing hysterectomy rates or abnormal uterine bleeding in women with endometrial hyperplasia. (cochrane.org)

Primary end points: This clinical trial is aimed to analyze the effectiveness of Levonorgestrel-Releasing Intrauterine System (LNG-IUS, Mirena) in the fertility-sparing treatment of atypical endometrial hyperplasia and early endometrial carcinoma, including pathology response and pregnancy outcome. (centerwatch.com)
416-8 Liebman W M WM Rosental E E eng Case Reports Journal Article United States West J Med 0410504 0093-0415 IM Colon pathology Female Humans Hyperplasia Infant Lymphatic System pathology 1977 11 1 1977 11 1 0 1 1977 11 1 0 0 ppublish 919544 PMC1237891 Fed Proc. (tripdatabase.com)

In addition, hyperplasia in the breast comes in two forms: duct epithelial hyperplasia (meaning the growth is in the milk ducts) or lobular hyperplasia (the growth is in the breast's lobules). (floridahospital.com)

In areas of inflammation or with the presence of calculi, the pathologist should use his or her judgment in deciding whether secondary urothelial hyperplasia is prominent enough to warrant a separate diagnosis. (nih.gov)

Women with atypical hyperplasia of the breast have a higher risk of developing breast cancer than previously thought, a Mayo Clinic study has found. (news-medical.net)
Women with atypical hyperplasia should talk to their doctor about a personal plan of testing for breast cancer, including regular mammography. (cancer.ca)
Women with atypical hyperplasia should talk to their healthcare team about the benefits and possible risks of taking SERMs to reduce their risk of breast cancer. (cancer.ca)
For women with atypical hyperplasia who also have a greater than 20 percent lifetime risk of invasive breast cancer, there are special breast cancer screening recommendations. (komen.org)
The NCCN recommends women with atypical hyperplasia who have a less than 20 percent lifetime risk of invasive breast cancer and women with usual hyperplasia get the same breast cancer screening as women at average risk . (komen.org)
The NCCN strongly recommends women with atypical hyperplasia (but not usual hyperplasia) take a risk-lowering drug (tamoxifen or raloxifene) to lower their risk of developing breast cancer [ 179 ]. (komen.org)
These drugs can lower the risk of breast cancer in women with atypical hyperplasia by 86 percent [ 179 ]. (komen.org)

The objective is to identify the utility of ultrasound as a screening test for endometrial hyperplasia and cancer in an 'at risk' cohort. (clinicaltrials.gov)

This risk is even higher in women who have a family history of breast cancer or who are diagnosed with atypical hyperplasia before they reach menopause . (cancer.ca)
One study found women diagnosed with atypical hyperplasia had about a 29 percent chance of developing breast cancer within 25 years [ 177 ]. (komen.org)

Similarly to physiological hyperplasia, cells that undergo pathologic hyperplasia are controlled by growth hormones , and cease to proliferate if such stimuli are removed. (wikipedia.org)
[10] That being said, the effects caused by pathologic hyperplasia can provide a suitable foundation from which neoplastic cells may develop. (wikipedia.org)
This is called pathologic hyperplasia. (medlineplus.gov)
The development of endometrial adenocarcinoma from endometrial hyperplasia is a typical example of how the effects of pathologic hyperplasia can lead to neoplasia, and females who exhibit hyperplasia of the endometrium are indeed more likely to develop cancer of these cells. (wikipedia.org)

Endometrial hyperplasia occurs when the endometrium , the lining of the uterus , becomes too thick. (acog.org)
If the endometrium is thick, it may mean that endometrial hyperplasia is present. (acog.org)
The hyperplastic process in the endometrium is, for the most part, diffuse involves both glands and stroma (simple hyperplasia), less frequently, is focal or multifocal, and affects exclusively endometrial glands (complex hyperplasia and usually atypical hyperplasia) [ 1 ]. (hindawi.com)
Endometrial hyperplasia - Hyperproliferation of the endometrium, usually in response to unopposed estrogen stimulation in the setting of polycystic ovary syndrome or exogenous administration of hormones. (bionity.com)

If you have atypical hyperplasia, especially complex atypical hyperplasia, the risk of cancer is increased. (acog.org)
PRIMARY OBJECTIVES: I. To determine if there is a decrease in proliferation index, measured by Ki-67 expression, in complex atypical hyperplasia (CAH)/endometrial intraepithelial neoplasia (EIN) or low grade (grade 1 and grade 2) endometrial cancer cells from baseline to post-exemestane treatment. (centerwatch.com)
PRIMARY OBJECTIVES: I. Estimate the efficacy of the levonorgestrel intrauterine device (LIUD) (levonorgestrel-releasing intrauterine system) alone to treat complex atypical hyperplasia or stage Ia grade 1 endometrioid endometrial carcinoma with response rate. (centerwatch.com)

In the case of endometrial hyperplasia usually a Pap smear is done, also a biopsy during the pelvic examination, may be done of the individuals endometrial tissue. (wikipedia.org)
The biopsy was reported as "endometrial stromal lesion "stromal hyperplasia" endometrial stromal nodule. (hindawi.com)
Histological assessment of the biopsy specimen revealed the hyperplasia of connective tissue, epithelial acanthosis, and elongated rete ridges along with few inflammatory cells. (isciii.es)
Microscopic inspection of the gingival biopsy specimens demonstrated a connective tissue hyperplasia, acanthosis of overlying epithelium, and elongated rete ridges together with few sparse inflammatory cells. (isciii.es)

Currently the standard treatment for early stage endometrial cancer or endometrial hyperplasia with atypia is a total hysterectomy (an operation to remove the uterus) and removal of both ovaries. (centerwatch.com)
Atypical hyperplasia is a benign (noncancerous) cellular hyperplasia in which cells show some atypia. (wikipedia.org)

We report here three such cases of stromal endometrial hyperplasia and reveal its subtle, but unique, features, for which this form of hyperplasia merits separate consideration. (hindawi.com)
In usual hyperplasia (the most common form of hyperplasia), the proliferating (dividing) cells look normal under a microscope. (komen.org)

Hyperplasia (from ancient Greek ὑπέρ huper , "over" + πλάσις plasis , "formation"), or hypergenesis , is an increase in the amount of organic tissue that results from cell proliferation . (wikipedia.org)
[11] Hyperplasia may be harmless and occur on a particular tissue. (wikipedia.org)
[14] With IGF use, one is able to cause hyperplasia which actually increases the number of muscle cells present in the tissue. (wikipedia.org)
Hyperplasia is increased cell production in a normal tissue or organ. (medlineplus.gov)
Hyperplasia is the increased cell production of normal tissue in the body which causes the organ to increase in size. (medlineplus.gov)
IRRADIATION TREATMENT OF LYMPHOID HYPERPLASIA OF THE NASOPHARYNX Irradiation is useful in the destruction of hypertrophied lymphoid tissue which cannot be surgically removed.Beta, gamma and roentgen rays have been used for this purpose. (tripdatabase.com)
A method is disclosed for inhibiting intimal hyperplasia in a warm-blooded mammal which comprises administering topically at the site and time of a vascular injury induced by arterial intervention in said mammal a small but inhibitorily effective amount of tissue factor pathway inhibitor (TFPI) sufficient. (google.com)
A method is disclosed for inhibiting intimal hyperplasia in a warm-blooded mammal which comprises administering topically at the site and time of a vascular injury induced by arterial intervention in said mammal a small but inhibitorily effective amount of tissue factor pathway inhibitor (TFPI) sufficient to inhibit said intimal hyperplasia. (google.com)
More particularly, the invention concerns a method for inhibiting intimal hyperplasia induced by arterial interventions by administering topically at the site and at the time of the vascular injury a blood coagulation inhibitor known as tissue factor pathway inhibitor (TFPI). (google.com)
Hyperplasia is an increase in the number of normal cells growing in a tissue. (cancer.ca)
Hyperplasia (or "hypergenesis") is a general term referring to the proliferation of cells within an organ or tissue beyond that which is ordinarily seen. (bionity.com)
Hyperplasia is a medical word for an organ or tissue growing too large. (umich.edu)

Whereas hypertrophy stems from an increase in cell size , hyperplasia results from an increase in cell number. (wikipedia.org)
[7] Hyperplasia is different from hypertrophy in that the adaptive cell change in hypertrophy is an increase in the size of cells , whereas hyperplasia involves an increase in the number of cells. (wikipedia.org)
To be accurate, the process is one of hyperplasia rather than hypertrophy , but the nomenclature is often interchangeable, even amongst urologists . (princeton.edu)

What are lymphoid polyps (lymphoid nodular hyperplasia)? (medscape.com)
In vitro and in vivo lymphocyte function was studied in six patients with primary hypogammaglobulinaemia and nodular lymphoid hyperplasia (NLH) of the bowel. (tripdatabase.com)
The study, Ileal-lymphoid-nodular hyperplasia , non-specific colitis, and pervasive developmental disorder in children concludes, "We have identified a chronic enterocolitis in children that may be related to neuropsychiatric dysfunction. (yourdictionary.com)

Pseudoangiomatous stromal hyperplasia (PASH) is a rare, benign (noncancerous) breast lesion. (healthline.com)
In this paper, we describe three examples of "endometrial stromal hyperplasia" which have a remarkable morphological similarity with the normally proliferating endometrial stroma and the endometrial stromal neoplasms, but which also possess subtle, but sufficient, differences to justify their taxonomic separation. (hindawi.com)
Endometrial stromal hyperplasia. (hindawi.com)
c) Endometrial stromal hyperplasia forming a small polyp composed of dense endometrial stroma with thick-walled vessels of the arteriolar type (H and E ×4). (hindawi.com)

A focus of urothelial hyperplasia is present in the renal pelvis adjacent to the renal papilla. (nih.gov)
Urothelial hyperplasia in the renal pelvis is associated with inflammation. (nih.gov)
Urothelial hyperplasia should be diagnosed and given a severity grade. (nih.gov)
Our current results show that ECS-exposed mice developed lung adenocarcinoma and bladder urothelial hyperplasia, indicating that ECS is a lung carcinogen and a potential bladder carcinogen in mice. (pnas.org)

As used herein, intimal hyperplasia (also referred to as neointimal hyperplasia) refers to the proliferative response to a vascular injury consisting almost entirely, although not exclusively, of smooth muscle cells (SMCs) which form an intimal lesion on the luminal surface around the inner circumference of a blood vessel (intima) following an arterial intervention such as, e.g., angioplasty or endarterectomy. (google.com)
The patented Spiral Luminal Flow[TM] technology was designed to prevent neointimal hyperplasia by decreasing turbulence and creating a spiral flow that mimics the blood flow of a native AV fistula into the venous system (Vascular Flow Technologies, 2017b). (thefreedictionary.com)
Neointimal hyperplasia in coronary vein grafts: pathophysiology and prevention of a significant clinical problem. (thefreedictionary.com)
Lycopene could remarkably alleviate neointimal hyperplasia and arteriosclerosis of the aortic grafts. (thefreedictionary.com)
The next steps in establishing the effect of the coating combinations on cell proliferation should include a revised method for viewing total number of cells within and determine optimal combinations to decrease cell proliferation and effectively neointimal hyperplasia once correlated in vivo. (thefreedictionary.com)
Metallic Surface Treatment Using Electrochemical Polishing Decreases Thrombogenicity and Neointimal Hyperplasia of Coronary Stents. (thefreedictionary.com)
Ariste has completed pre-clinical models demonstrating proof-of-concept using ePTFE grafts coated with rapamycin and has achieved a significant reduction in neointimal hyperplasia , or scarring within the graft. (thefreedictionary.com)
Conclusion: EPCs derived from human early fetal aorta were successfully transplanted into injured vessels and might inhibit neointimal hyperplasia after vascular injury. (thefreedictionary.com)

However, thymomas are nodular and compressing, whereas hyperplasias are not. (nih.gov)
Focal nodular hyperplasia (FNH) in liver is the second common benign hepatic tumor. (clinicaltrials.gov)

Hyperplasia may be due to any number of causes, including proliferation of basal layer of epidermis to compensate skin loss, chronic inflammatory response , hormonal dysfunctions , or compensation for damage or disease elsewhere. (wikipedia.org)

Prostate hyperplasia, also known as benign prostate hyperplasia (BPH), is a fairly common problem for men. (selfgrowth.com)

Hyperplasia may also occur abnormally, and is associated with a variety of clinical diseases. (bionity.com)
The histological and the clinical evidences were consistent with amlodipine-induced gingival hyperplasia. (isciii.es)
The lesion was diagnosed as amlodipine-induced gingival hyperplasia based on clinical and histological evidences. (isciii.es)

just google sebaceous hyperplasia treatment,its the one with the bearded man. (essentialdayspa.com)
Sebaceous hyperplasia - In this condition, small yellowish growths develop on the skin, usually on the face. (bionity.com)
What is sebaceous hyperplasia? (zocdoc.com)
Zocdoc › Answers › What is sebaceous hyperplasia? (zocdoc.com)
My girlfriend has this problem with her skin that she says is sebaceous hyperplasia - what is it? (zocdoc.com)
Sebaceous hyperplasia is a common condition. (zocdoc.com)
Sebaceous hyperplasia is a disorder of the sebaceous glands. (zocdoc.com)
In sebaceous hyperplasia, these glands overgrow and become enlarged and visible. (zocdoc.com)
While sebaceous glands exist everywhere there is hair, in sebaceous hyperplasia you often see them and are troubled by the ones located on the face. (zocdoc.com)

Focal epithelial hyperplasia (also known as Heck's disease) - This is a wart-like growth in the mucous tissues of the mouth or, rarely, throat that is caused by certain sub-types of the human papillomavirus (HPV). (bionity.com)
Thymic epithelial hyperplasia is found in the medulla and may be focal to diffuse. (nih.gov)

Endometrial hyperplasia usually occurs after menopause , when ovulation stops and progesterone is no longer made. (acog.org)
Hyperplasia occurs gradually over a period of days to several weeks following the arterial intervention, as distinguished from a thrombus, such as may occur in the circulating blood immediately at the time of intervention. (google.com)
Endometrial hyperplasia occurs more commonly than endometrial cancer. (cochrane.org)

What treatments are available for endometrial hyperplasia? (acog.org)
Minimally invasive procedures have gained great importance among the treatments for benign prostate hyperplasia (BPH) due to their low morbidity. (urotoday.com)

[ 1 ] It is characterized by hyperplasia of prostatic stromal and epithelial cells, resulting in the formation of large, fairly discrete nodules in the periurethral region of the prostate. (princeton.edu)

However, data comparing embolization with transurethral resection of the prostate, which is still the surgical gold standard in the treatment of benign hyperplasia, is still lacking and highly warranted," he added. (medscape.com)
The increasing utilization of holmium enucleation has led to the development of various modifications of this treatment modality, including the so-called enucleation as a single piece (HoLEP en bloc), which reduces the operative time and, according to some authors, facilitates acquiring new surgical technique by surgical trainees. (urotoday.com)
Treatment for endometrial hyperplasia includes taking hormones, having a dilation and curettage (D&C), having a procedure to destroy the inner lining of the uterus (endometrial ablation), or having surgery to remove the uterus (hysterectomy). (cigna.com)
Is metformin an effective and safe treatment for people with endometrial hyperplasia? (cochrane.org)
Successful treatment of women with endometrial hyperplasia can prevent endometrial cancer. (cochrane.org)
Also, progesterone tablets do not always work, and endometrial hyperplasia can return in up to 14% to 30% of women after treatment. (cochrane.org)
Therefore, an alternative treatment for endometrial hyperplasia is required. (cochrane.org)
At present, evidence is insufficient to support or refute the use of metformin alone or in combination with standard therapy - specifically, megestrol acetate - versus megestrol acetate alone, for treatment of endometrial hyperplasia. (cochrane.org)
Therefore, an alternative treatment for women with endometrial hyperplasia is needed. (cochrane.org)

This might reassure you that this is atypical hyperplasia and not an early form of breast cancer. (breastcancer.org)
In some cases, the hyperplasia cells can look exactly like normal, healthy breast cells. (breastcancer.org)
W. H. Kern and R. N. Brooks, "Atypical epithelial hyperplasia associated with breast cancer and fibrocystic disease," Cancer , vol. 24, no. 4, pp. 668-675, 1969. (hindawi.com)
It is the most common type of atypical hyperplasia of the breast. (cancer.ca)
Having atypical hyperplasia increases the risk for breast cancer. (cancer.ca)
Breast cancer is more likely to start in the breast where atypical hyperplasia is found. (cancer.ca)
The risk of developing breast cancer is greatest 10-15 years after atypical hyperplasia is diagnosed. (cancer.ca)
You may be offered chemoprevention if you have atypical hyperplasia of the breast, especially if you have a family history of breast cancer. (cancer.ca)
The most common type of proliferative breast condition is hyperplasia. (komen.org)
Women with usual hyperplasia have about twice the breast cancer risk of women without a proliferative breast condition [ 174-175 ]. (komen.org)
For a summary of research studies on hyperplasia and breast cancer, visit the Breast Cancer Research Studies section . (komen.org)
Atypical hyperplasia is a high-risk premalignant lesion of the breast. (wikipedia.org)

This condition, called hyperplasia, may lead to cancer in some women. (acog.org)
what is atypical melanocytic hyperplasia and is it a serious condition? (medhelp.org)
You might hear a doctor or nurse call that condition "benign prostate hyperplasia," or BPH . (webmd.com)
Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon, vasoproliferative, idiopathic condition that manifests in adults as isolated or grouped papules, plaques, or nodules in the skin of the head and neck. (medscape.com)
Endometrial hyperplasia is a precancerous condition in women that can lead to endometrial cancer, if left untreated. (cochrane.org)

Adenoid hyperplasia is an enlargement of the lymph glands located above the back of the mouth. (encyclopedia.com)
All MEN types are the result of inherited genetic mutations that predispose the individual to excessive growth of cells ( hyperplasia ) and tumor formation in multiple endocrine glands. (yourdictionary.com)

Compensatory liver hyperplasia - The liver undergoes cellular division after acute injury, resulting in new cells that restore liver function back to baseline. (bionity.com)
Pleomorphic variations of thymic epithelial hyperplasia are similar to the spectrum of cellular forms of thymoma. (nih.gov)

After diagnosed of endometrial atypical hyperplasia (EAH) by hysteroscopy, patients will be enrolled. (centerwatch.com)
Gingival hyperplasia with its potential cosmetic implications and also providing new niches for the growth of microorganisms is a serious concern for both the patients and clinician. (isciii.es)
In a series of 150 cardiac patients, it was found that amlodipine at a dose of 5 mg/day can not induce gingival hyperplasia even if taken more than 6 months (6). (isciii.es)
reported three patients with poor periodontal conditions who developed gingival hyperplasia upon a chronic usage (at least three moths) of amlodipine (3). (isciii.es)

The true incidence of adenoid hyperplasia is difficult to assess. (encyclopedia.com)
Although the incidence of nifedipine-induced gingival hyperplasia is about 10% (3), very few reports of amlodipine-related gingival hyperplasia does exist in the extant literature (3,5,6). (isciii.es)

If endometrial hyperplasia is not treated, it may progress to endometrial cancer. (cigna.com)
Although both studies provided data on progression of endometrial hyperplasia to endometrial cancer, there were no events in either arm, and study authors reported no data on adverse effects. (cochrane.org)

Anatomy23

Organisms8

Diseases49

Chemicals and Drugs13

Analytical, Diagnostic and Therapeutic Techniques and Equipment17

Phenomena and Processes4

Disciplines and Occupations1

Technology, Industry, Agriculture1

The epizootiology and pathogenesis of thyroid hyperplasia in coho salmon (Oncorhynchus kisutch) in Lake Ontario. (1/4620)

Natural history of papillary lesions of the urinary bladder in schistosomiasis. (2/4620)

Ganglioneuromas and renal anomalies are induced by activated RET(MEN2B) in transgenic mice. (3/4620)

Anti-monocyte chemoattractant protein-1/monocyte chemotactic and activating factor antibody inhibits neointimal hyperplasia in injured rat carotid arteries. (4/4620)

Myometrial zonal differentiation and uterine junctional zone hyperplasia in the non-pregnant uterus. (5/4620)

Mechanism of parathyroid tumourigenesis in uraemia. (6/4620)

Accelerated intimal hyperplasia and increased endogenous inhibitors for NO synthesis in rabbits with alloxan-induced hyperglycaemia. (7/4620)

Expression of relaxin-like factor is down-regulated in human testicular Leydig cell neoplasia. (8/4620)

Hyperplasia

Prostatic Hyperplasia

Endometrial Hyperplasia

Adrenal Hyperplasia, Congenital

Gingival Hyperplasia

Thymus Hyperplasia

Focal Nodular Hyperplasia

Tunica Intima

Focal Epithelial Hyperplasia

Neointima

Angiolymphoid Hyperplasia with Eosinophilia

Steroid 21-Hydroxylase

Precancerous Conditions

Pseudolymphoma

Prostate

Parathyroid Glands

Immunohistochemistry

Endometrial Neoplasms

Transurethral Resection of Prostate

Carotid Artery Injuries

Adenoma

17-alpha-Hydroxyprogesterone

Graft Occlusion, Vascular

Jugular Veins

Goblet Cells

Giant Lymph Node Hyperplasia

Disease Models, Animal

Mice, Transgenic

Parathyroid Diseases

Adrenocortical Hyperfunction

5-alpha Reductase Inhibitors

Cell Division

Muscle, Smooth, Vascular

Cell Proliferation

Hypertrophy

Polytetrafluoroethylene

Papilloma

Organ Size

Parathyroid Neoplasms

Vascular Grafting

Rats, Inbred F344

Cushing Syndrome

Carotid Arteries

Adrenal Glands

Serenoa

Breast Diseases

Finasteride

Prostatic Neoplasms

Epidermis

Adrenal Gland Diseases

Carcinoma in Situ

Myocytes, Smooth Muscle

Veins

Endometrium

Angioplasty, Balloon

Carcinogens

Azasteroids

Proliferating Cell Nuclear Antigen

Time Factors

Carcinogenicity Tests

Mammary Glands, Animal

Mice, Inbred C57BL

Iliac Artery

Epithelium

Hyperparathyroidism

Breast

Mice, Knockout

Rats, Sprague-Dawley

Adenoma, Liver Cell

Biopsy

Fibrocystic Breast Disease

Adrenal Cortex Neoplasms

Metaplasia

Adenomatosis, Pulmonary

Femoral Artery

Urinary Bladder Neck Obstruction

Catheterization

Adenocarcinoma

Cells, Cultured

Enterochromaffin Cells