A species of tapeworm (TAPEWORMS) infecting RATS and MICE but rarely causing disease in humans. Its life cycle involves RODENTS as the definitive host and BEETLES as the intermediate host.
A genus of small tapeworms of birds and mammals.
Infection with tapeworms of the genus Hymenolepis.
A subclass of segmented worms comprising the tapeworms.
The smallest species of TAPEWORMS. It is the only cestode that parasitizes humans without requiring an intermediate host.
An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
Infections with true tapeworms of the helminth subclass CESTODA.
A family of stalked bacteria that reproduces by budding. There are four genera: CAULOBACTER, Asticcacaulis, Brevundimonas, and Phenylobacterium.
Infestation of animals with parasitic worms of the helminth class. The infestation may be experimental or veterinary.
Infections of the INTESTINES with PARASITES, commonly involving PARASITIC WORMS. Infections with roundworms (NEMATODE INFECTIONS) and tapeworms (CESTODE INFECTIONS) are also known as HELMINTHIASIS.
Commonly known as parasitic worms, this group includes the ACANTHOCEPHALA; NEMATODA; and PLATYHELMINTHS. Some authors consider certain species of LEECHES that can become temporarily parasitic as helminths.
Infections with unicellular organisms formerly members of the subkingdom Protozoa.
A class of enzymes that catalyze the hydrolysis of one of the three ester bonds in a phosphotriester-containing compound.
A genus of gram-negative, aerobic, rod-shaped bacteria widely distributed in nature. Some species are pathogenic for humans, animals, and plants.

Overview of hymenolepis diminuta infection among Thai patients. (1/13)

CONTEXT: Hymenolepis diminuta infection is a very rare cestode infection. Until present, fewer than 500 cases have been observed worldwide. OBJECTIVE: The author performed a literature review on the reports of H diminuta in Thailand in order to summarize the characteristics of this infection among Thai patients. DESIGN: This study was designed as a descriptive retrospective study. A literature review of the papers concerning H diminuta infections in Thailand was performed. RESULTS: According to this study, there have been at least 6 reports in the literature of 10 individual cases of H diminuta infection, of which 1 case was lethal. Of 4 cases that documented patients' age, the ages ranged from 20 months to 55 years. Of 5 cases that documented patients' sex, 3 were males and 2 were females. Most (9/10) were asymptomatic; however, there was 1 inpatient case, concomitant with metastatic cholangiocarcinoma. Antiparasitic drugs were prescribed in 3 cases: niclosamide in 2 cases and praziquantel in 1 case. The 2 patients receiving niclosamide passed the parasites after treatment. CONCLUSION: In conclusion, the H diminuta infection is a rare cestode infection that is sporadically reported in Thailand. The diagnosis of H diminuta infection is usually by accident during a field survey. The prognosis outcome is usually good, and the treatment does not appear to affect outcome, as there is good survival without treatment.  (+info)

Costly resistance to parasitism: evidence from simultaneous quantitative trait loci mapping for resistance and fitness in Tribolium castaneum. (2/13)

Information on the molecular basis of resistance and the evolution of resistance is crucial to an understanding of the appearance, spread, and distribution of resistance genes and of the mechanisms of host adaptation in natural populations. One potential important genetic constraint for the evolution of resistance is fitness cost associated with resistance. To determine whether host resistance to parasite infection is associated with fitness costs, we conducted simultaneous quantitative trait loci (QTL) mapping of resistance to parasite infection and fitness traits using the red flour beetle (Tribolium castaneum) and the tapeworm parasite (Hymenolepis diminuta) system in two independent segregating populations. A genome-wide QTL scan using amplified fragment length polymorphism (AFLP) markers revealed three QTL for beetle resistance to tapeworm infection. These three QTL account for 44-58% variance in beetle infection intensity. We identified five QTL for fecundity and five QTL for egg-to-adult viability, which accounted for 36-57% and 36-49%, respectively, of the phenotypic variance in fecundity and egg-to-adult viability. The three QTL conferring resistance were colocalized with the QTL affecting beetle fitness. The genome regions that contain the QTL for parasite resistance explained the majority of the variance in fecundity and egg-to-adult viability in the mapping populations. Colocalization of QTL conferring resistance to parasite infection and beetle fitness may result from the pleiotropic effects of the resistance genes on host fitness or from tight linkages between resistance genes and adverse deleterious mutations. Therefore, our results provide evidence that the genome regions conferring resistance to tapeworm infection are partially responsible for fitness costs in the resistant beetle populations.  (+info)

Neutralizing anti-IL-10 antibody blocks the protective effect of tapeworm infection in a murine model of chemically induced colitis. (3/13)

There is increasing evidence that parasitic helminth infection has the ability to ameliorate other disease conditions. In this study the ability of the rat tapeworm, Hymenolepis diminuta, to modulate dinitrobenzene sulfonic acid (DNBS)-induced colitis in mice is assessed. Mice receiving DNBS (3 mg intrarectally) developed colitis by 72 h after treatment. Mice infected 8 days before DNBS with five H. diminuta larvae were significantly protected from the colitis, as gauged by reduced clinical disease, histological damage scores, and myeloperoxidase levels. This anticolitic effect was dependent on a viable infection and helminth rejection, because no benefit was observed in mice given killed larvae or in infected STAT6 knockout mice or rats, neither of which eliminate H. diminuta. The anticolitic effect of H. diminuta was associated with increased colonic IL-10 mRNA and stimulated splenocytes from H. diminuta- plus DNBS-treated mice produced more IL-10 than splenocytes from DNBS-only treated mice. Coadministration of an anti-IL-10 Ab blocked the anticolitic effect of prophylactic H. diminuta infection. Also, mice infected 48 h after DNBS treatment showed an enhanced recovery response. Finally, using a model of OVA hypersensitivity, we found no evidence of concomitant H. diminuta infection enhancing enteric responsiveness to subsequent ex vivo OVA challenge. The data show that a viable infection of H. diminuta in a nonpermissive system exerts a profound anticolitic effect (both prophylactically and as a treatment) that is mediated at least in part via IL-10 and does not predispose to enhanced sensitivity to bystander proteins.  (+info)

Hymenolepis diminuta in a child from rural area. (4/13)

We report a rare case of Hymenolepis diminuta infection in a 12-year-old girl from a rural area of Devghar.  (+info)

Increased glial-derived neurotrophic factor in the small intestine of rats infected with the tapeworm, Hymenolepis diminuta. (5/13)

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Infection with Hymenolepis diminuta is more effective than daily corticosteroids in blocking chemically induced colitis in mice. (6/13)

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Extracts of the rat tapeworm, Hymenolepis diminuta, suppress macrophage activation in vitro and alleviate chemically induced colitis in mice. (7/13)

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A human case of Hymenolepis diminuta in a child from eastern Sicily. (8/13)

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'Hymenolepis diminuta' is a species of tapeworm that infects rodents and, less commonly, humans. The adult worm typically measures 20-60 cm in length and inhabits the small intestine of its host. Infection in humans usually occurs through ingestion of infected transport hosts such as beetles or fleas, which can occur through the consumption of contaminated food or drink.

The medical definition of 'Hymenolepis diminuta' is a parasitic infection caused by the tapeworm Hymenolepis diminuta, also known as dwarf tapeworm. Symptoms of infection may include abdominal discomfort, diarrhea, and weight loss, although many infections are asymptomatic. Diagnosis is typically made through the identification of eggs or proglottids (segments of the worm) in the stool. Treatment usually involves administration of a medication called niclosamide, which kills the tapeworm. Preventive measures include practicing good hygiene and food safety habits to reduce the risk of ingesting infected transport hosts.

Hymenolepis is a genus of tapeworms that are commonly found in rodents and other small mammals, but can also infect humans. The two species that are most relevant to human health are Hymenolepis nana and Hymenolepis diminuta.

Hymenolepis nana, also known as the dwarf tapeworm, is the smallest tapeworm that infects humans. It is unique among tapeworms because it can complete its entire life cycle within a single host, without needing an intermediate host. This means that it can be transmitted directly from person to person through contaminated food or water.

Hymenolepis diminuta, on the other hand, requires an intermediate host, such as a beetle or grain moth, to complete its life cycle. Humans can become infected by accidentally ingesting these insects, which may be found in contaminated grains or other food products.

Both species of Hymenolepis can cause similar symptoms in humans, including abdominal pain, diarrhea, and weight loss. In severe cases, they can also lead to more serious complications such as intestinal obstruction or nutritional deficiencies.

It's worth noting that while Hymenolepis infections are not uncommon in certain parts of the world, they are relatively rare in developed countries with good sanitation and hygiene practices. Treatment typically involves taking medication to kill the tapeworms, such as niclosamide or praziquantel.

Hymenolepiasis is a parasitic infection caused by the tapeworms Hymenolepis nana (dwarf tapeworm) or Hymenolepis diminuta (rat tapeworm).

The dwarf tapeworm, H. nana, is the most common cause of hymenolepiasis and can complete its life cycle within a single host, making human-to-human transmission possible through the fecal-oral route. This means that eggs are ingested, often through contaminated food or water, and then hatched in the small intestine, where they develop into adult tapeworms.

On the other hand, H. diminuta requires an intermediate host, usually a rat or beetle, to complete its life cycle. Humans can become infected by ingesting the infected insect or contaminated food.

Symptoms of hymenolepiasis may include abdominal discomfort, diarrhea, loss of appetite, and weight loss. In severe cases, anemia and intestinal inflammation can occur. The infection is typically diagnosed through the identification of eggs or tapeworm segments in stool samples. Treatment usually involves administering a course of medication that targets the parasite, such as praziquantel or niclosamide.

Cestoda is a class of parasitic worms belonging to the phylum Platyhelminthes, also known as flatworms. Cestodes are commonly known as tapeworms and have a long, flat, segmented body that can grow to considerable length in their adult form. They lack a digestive system and absorb nutrients through their body surface.

Cestodes have a complex life cycle involving one or two intermediate hosts, usually insects or crustaceans, and a definitive host, which is typically a mammal, including humans. The tapeworm's larval stage develops in the intermediate host, and when the definitive host consumes the infected intermediate host, the larvae mature into adults in the host's intestine.

Humans can become infected with tapeworms by eating raw or undercooked meat from infected animals or through accidental ingestion of contaminated water or food containing tapeworm eggs or larvae. Infection with tapeworms can cause various symptoms, including abdominal pain, diarrhea, weight loss, and vitamin deficiencies.

Hymenolepis nana, also known as the dwarf tapeworm, is a small intestine-infecting cestode parasite that primarily affects humans and rodents. The adult worms are typically 15-40 mm in length and have a scolex (head) with four suckers but no hooks. The proglottids (segments) of the worm contain both male and female reproductive organs, allowing for self-fertilization.

The life cycle of Hymenolepis nana can be direct or indirect. In the direct life cycle, eggs are passed in the feces of an infected individual and ingested by another person through contaminated food, water, or fomites (inanimate objects). Once inside the human host, the eggs hatch in the small intestine, releasing oncospheres that invade the intestinal wall and develop into cysticercoids. The cysticercoids then mature into adult tapeworms within 10-15 days.

In the indirect life cycle, eggs are ingested by an intermediate host, usually a beetle or flea, where they hatch and develop into cysticercoids. When the infected insect is consumed by a rodent or human, the cysticercoids excyst in the small intestine and mature into adult tapeworms.

Symptoms of Hymenolepis nana infection can range from mild to severe and may include abdominal discomfort, diarrhea, loss of appetite, weight loss, and anemia. In some cases, particularly in children or individuals with weakened immune systems, the infection can lead to more serious complications such as intestinal obstruction or inflammation of the small intestine (enteritis).

Niclosamide is an antihelminthic medication, which means it is used to treat infections caused by parasitic worms. It works by disrupting the metabolism of the worms, leading to their elimination from the body. Niclosamide is specifically indicated for the treatment of tapeworm infections (such as Taenia saginata, Taenia solium, and Hymenolepis nana).

It's important to note that niclosamide is not typically absorbed into the human body when taken as directed, so it primarily affects the worms in the digestive tract. However, if you have any specific questions about niclosamide or its use, please consult a healthcare professional for medical advice tailored to your particular circumstances.

Cestode infections, also known as tapeworm infections, are caused by the ingestion of larval cestodes (tapeworms) present in undercooked meat or contaminated water. The most common types of cestode infections in humans include:

1. Taeniasis: This is an infection with the adult tapeworm of the genus Taenia, such as Taenia saginata (beef tapeworm) and Taenia solium (pork tapeworm). Humans become infected by consuming undercooked beef or pork that contains viable tapeworm larvae. The larvae then mature into adult tapeworms in the human intestine, where they can live for several years, producing eggs that are passed in the feces.
2. Hydatid disease: This is a zoonotic infection caused by the larval stage of the tapeworm Echinococcus granulosus, which is commonly found in dogs and other carnivores. Humans become infected by accidentally ingesting eggs present in dog feces or contaminated food or water. The eggs hatch in the human intestine and release larvae that migrate to various organs, such as the liver or lungs, where they form hydatid cysts. These cysts can grow slowly over several years and cause symptoms depending on their location and size.
3. Diphyllobothriasis: This is an infection with the fish tapeworm Diphyllobothrium latum, which is found in freshwater fish. Humans become infected by consuming raw or undercooked fish that contain viable tapeworm larvae. The larvae mature into adult tapeworms in the human intestine and can cause symptoms such as abdominal pain, diarrhea, and vitamin B12 deficiency.

Preventing cestode infections involves practicing good hygiene, cooking meat thoroughly, avoiding consumption of raw or undercooked fish, and washing fruits and vegetables carefully before eating. In some cases, treatment with antiparasitic drugs may be necessary to eliminate the tapeworms from the body.

Caulobacteraceae is a family of gram-negative, aerobic bacteria that are widely distributed in aquatic environments. These bacteria are known for their unique bipolar morphology, with one end (the "stalked" end) attached to surfaces and the other end (the "stalkless" end) free-swimming. The stalked end is used for attachment to surfaces and absorbing nutrients, while the stalkless end is used for movement and seeking out new surfaces to attach to.

Caulobacteraceae are important members of the microbial communities found in many aquatic environments, including freshwater, marine, and wastewater systems. Some species of Caulobacteraceae are capable of fixing nitrogen gas from the atmosphere, making them important contributors to the global nitrogen cycle.

One notable feature of Caulobacteraceae is their ability to form dormant, spore-like structures called "cysts" in response to environmental stressors such as nutrient limitation or desiccation. These cysts can remain viable for long periods of time and serve as a means of survival and dispersal for the bacteria.

Caulobacteraceae are also known for their complex life cycles, which involve a series of developmental stages that include cell division, differentiation, and motility. The study of Caulobacteraceae has provided important insights into the mechanisms of bacterial cell division, differentiation, and motility, as well as the regulation of gene expression in response to environmental cues.

Helminthiasis, in general, refers to the infection or infestation of humans and animals by helminths, which are parasitic worms. When referring to "Animal Helminthiasis," it specifically pertains to the condition where animals, including domestic pets and livestock, are infected by various helminth species. These parasitic worms can reside in different organs of the animal's body, leading to a wide range of clinical signs depending on the worm species and the location of the infestation.

Animal Helminthiasis can be caused by different types of helminths:

1. Nematodes (roundworms): These include species like Ascaris suum in pigs, Toxocara cati and Toxascaris leonina in cats, and Toxocara canis in dogs. They can cause gastrointestinal issues such as diarrhea, vomiting, and weight loss.
2. Cestodes (tapeworms): Examples include Taenia saginata in cattle, Echinococcus granulosus in sheep and goats, and Dipylidium caninum in dogs and cats. Tapeworm infestations may lead to gastrointestinal symptoms like diarrhea or constipation and may also cause vitamin deficiencies due to the worm's ability to absorb nutrients from the host animal's digestive system.
3. Trematodes (flukes): These include liver flukes such as Fasciola hepatica in sheep, goats, and cattle, and schistosomes that can affect various animals, including birds and mammals. Liver fluke infestations may cause liver damage, leading to symptoms like weight loss, decreased appetite, and jaundice. Schistosome infestations can lead to issues in multiple organs depending on the species involved.

Preventing and controlling Helminthiasis in animals is crucial for maintaining animal health and welfare, as well as ensuring food safety for humans who consume products from these animals. Regular deworming programs, good hygiene practices, proper pasture management, and monitoring for clinical signs are essential components of a comprehensive parasite control strategy.

Parasitic intestinal diseases are disorders caused by microscopic parasites that invade the gastrointestinal tract, specifically the small intestine. These parasites include protozoa (single-celled organisms) and helminths (parasitic worms). The most common protozoan parasites that cause intestinal disease are Giardia lamblia, Cryptosporidium parvum, and Entamoeba histolytica. Common helminthic parasites include roundworms (Ascaris lumbricoides), tapeworms (Taenia saginata and Taenia solium), hookworms (Ancylostoma duodenale and Necator americanus), and pinworms (Enterobius vermicularis).

Parasitic intestinal diseases can cause a variety of symptoms, including diarrhea, abdominal pain, bloating, nausea, vomiting, fatigue, and weight loss. The severity and duration of the symptoms depend on the type of parasite, the number of organisms present, and the immune status of the host.

Transmission of these parasites can occur through various routes, including contaminated food and water, person-to-person contact, and contact with contaminated soil or feces. Preventive measures include practicing good hygiene, washing hands thoroughly after using the toilet and before handling food, cooking food thoroughly, and avoiding consumption of raw or undercooked meat, poultry, or seafood.

Treatment of parasitic intestinal diseases typically involves the use of antiparasitic medications that target the specific parasite causing the infection. In some cases, supportive care such as fluid replacement and symptom management may also be necessary.

Helminths are a type of parasitic worm that can infect humans and animals. They are multi-cellular organisms that belong to the phyla Platyhelminthes (flatworms) or Nematoda (roundworms). Helminths can be further classified into three main groups: nematodes (roundworms), cestodes (tapeworms), and trematodes (flukes).

Helminth infections are typically acquired through contact with contaminated soil, food, or water. The symptoms of helminth infections can vary widely depending on the type of worm and the location and extent of the infection. Some common symptoms include abdominal pain, diarrhea, anemia, and malnutrition.

Helminths have complex life cycles that often involve multiple hosts. They can be difficult to diagnose and treat, and in some cases, may require long-term treatment with anti-parasitic drugs. Preventive measures such as good hygiene practices, proper sanitation, and access to clean water can help reduce the risk of helminth infections.

Protozoan infections are diseases caused by microscopic, single-celled organisms known as protozoa. These parasites can enter the human body through contaminated food, water, or contact with an infected person or animal. Once inside the body, they can multiply and cause a range of symptoms depending on the type of protozoan and where it infects in the body. Some common protozoan infections include malaria, giardiasis, amoebiasis, and toxoplasmosis. Symptoms can vary widely but may include diarrhea, abdominal pain, fever, fatigue, and skin rashes. Treatment typically involves the use of antiprotozoal medications to kill the parasites and alleviate symptoms.

Phosphoric triester hydrolases are a class of enzymes that catalyze the hydrolysis of phosphoric triesters into corresponding alcohols and phosphates. These enzymes play a crucial role in the detoxification of organophosphate pesticides and nerve agents, as well as in the metabolism of various endogenous compounds.

The term "phosphoric triester hydrolases" is often used interchangeably with "phosphotriesterases" or "organophosphorus hydrolases." These enzymes are characterized by their ability to cleave the P-O-C bond in phosphoric triesters, releasing a free alcohol and a diethyl phosphate moiety.

Phosphoric triester hydrolases have attracted significant interest due to their potential applications in bioremediation, biosensors, and therapeutics. However, it is important to note that the specificity and efficiency of these enzymes can vary widely depending on the structure and properties of the target compounds.

"Pseudomonas" is a genus of Gram-negative, rod-shaped bacteria that are widely found in soil, water, and plants. Some species of Pseudomonas can cause disease in animals and humans, with P. aeruginosa being the most clinically relevant as it's an opportunistic pathogen capable of causing various types of infections, particularly in individuals with weakened immune systems.

P. aeruginosa is known for its remarkable ability to resist many antibiotics and disinfectants, making infections caused by this bacterium difficult to treat. It can cause a range of healthcare-associated infections, such as pneumonia, bloodstream infections, urinary tract infections, and surgical site infections. In addition, it can also cause external ear infections and eye infections.

Prompt identification and appropriate antimicrobial therapy are crucial for managing Pseudomonas infections, although the increasing antibiotic resistance poses a significant challenge in treatment.

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